CN111529579A

CN111529579A - A Chinese medicinal composition for relieving hangover and treating alcoholic liver

Info

Publication number: CN111529579A
Application number: CN202010464483.6A
Authority: CN
Inventors: 仲崇允
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-05-28
Filing date: 2020-05-28
Publication date: 2020-08-14
Also published as: CN112494550A

Abstract

The invention discloses a traditional Chinese medicine for sobering up and treating alcoholic liver, which is prepared from the following raw material medicines in parts by weight: 4.5-9 parts by weight of ginseng; 9-18 parts by weight of kudzu root, hovenia dulcis thunb, bupleurum chinense and dandelion root; 15-30 parts of kalimeris indica.

Description

A Chinese medicinal composition for relieving hangover and treating alcoholic liver

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for sobering up and treating alcoholic liver.

Background

Alcoholic liver is a liver disease caused by long-term heavy drinking. According to epidemiological investigation data, liver damage caused by alcohol has a threshold effect, namely, a certain drinking capacity or drinking age limit is reached, and the risk of liver damage is greatly increased. At present, no specific medicine for treating alcoholic liver is available.

Disclosure of Invention

The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for sobering up and treating alcoholic liver, which can effectively improve and even eliminate the clinical symptoms of patients and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.

The harm of alcoholism in traditional Chinese medicine is recognized for a long time, and the golden lack, the jaundice pulse syndrome and the treatment have the name of alcoholic jaundice, and alcoholic jaundice is the existing alcoholic liver. At present, the traditional Chinese medicine considers that the main pathogenesis of alcoholic liver disease is that internal dampness is a disease, cold-dampness is accumulated in the interior or dampness stagnation is transformed into heat, and further spleen deficiency and liver depression and liver dysfunction are caused, heat and toxic materials are cleared away, liver soothing and stomach harmonizing are performed, spleen tonifying and lung benefiting are performed, dampness is promoted, and fluid is generated.

Based on the theory, the invention provides a traditional Chinese medicine for sobering up and treating alcoholic liver, which is prepared from the following raw material medicines in parts by weight: 4.5-9 parts by weight of ginseng; 9-18 parts by weight of kudzu root, hovenia dulcis thunb, bupleurum chinense and dandelion root; 15-30 parts of kalimeris indica.

In a preferred embodiment, the traditional Chinese medicine composition for sobering up and treating alcoholic liver is composed of the following raw material medicines in parts by weight: 9 parts of ginseng; 18 parts by weight of kudzu root, hovenia dulcis thunb, bupleurum chinense and dandelion root; and 30 parts of Indian kalimeris herb.

Wherein, root of kudzu vine: sweet and pungent with mild flavor enter spleen and stomach meridians. Expelling pathogenic factors from muscles and skin, allaying fever, promoting salivation, promoting eruption, invigorating yang, and relieving diarrhea. The kudzu root can promote metabolism, strengthen the detoxification function of the liver, obviously resist chronic alcoholic liver injury, improve the regeneration capacity of liver cells and restore normal liver function.

Ginseng: sweet, slightly bitter and neutral. It enters spleen, lung and heart meridians. Tonify primordial qi, recover pulse to stop collapse, tonify spleen and lung, promote fluid production, and induce tranquilization. The ginseng has obvious detoxification effect on ethanol, can shorten the duration of ethanol anesthesia and accelerate the recovery time, can reduce the contents of GOT, GPT, ALP, bilirubin and the like in serum, can increase the activities of alcohol dehydrogenase and aldehyde dehydrogenase related to ethanol metabolism, can quickly discharge toxic substance acetaldehyde generated by ethanol metabolism out of the body, and can effectively protect the liver suffering from ethanol poisoning because excessive hydrogen participates in saponin synthesis.

Raisin tree seed: sweet and neutral. Clearing away heat, promoting urination, quenching thirst, relieving restlessness, relieving alcoholism, and promoting urination and defecation. Can be used for treating constipation and alcoholism. Semen Hoveniae has effects of relieving hangover, accelerating ethanol metabolism, enhancing alcohol dehydrogenase activity, shortening hangover relieving time, and significantly inhibiting accumulation of ALT (glutamic-pyruvic transaminase), AST (glutamic-oxalacetic transaminase), MDA (malondialdehyde), TG (triglyceride), and TC (serum total cholesterol) caused by ethanol + LPS.

Dandelion root: bitter, sweet and cold. It enters liver and stomach meridians. Clearing away heat and toxic material, dispersing swelling and dissipating stagnation, inducing diuresis and treating stranguria. Has excellent liver cleaning and strengthening effects, and has effects in tonifying liver and gallbladder, and improving blood circulation.

And (3) kalimeris indica: 2, pungent taste; is cool in nature. Entering the lung; liver; the stomach; the large intestine channel. Cool blood, clear heat, promote diuresis, remove toxicity, break old blood, nourish new blood, relieve alcoholic jaundice.

Bupleurum tenue: 2, pungent taste; bitter; is cool in nature. Enter liver and gallbladder meridians. Soothing liver, regulating stomach, dispelling wind and clearing heat; detoxify and detumescence. Bupleurum tenue has effects of relieving alcoholism, protecting liver and stomach, improving anti-stress effect of human body and decomposition capability of liver on alcohol, and relieving intoxication symptoms after drinking, such as fullness in chest and hypochondrium, vexation and vomiting, bitter taste in mouth, dry throat, dizziness and headache.

The invention is prepared from Chinese traditional herbal medicines, and the traditional Chinese medicine for effectively treating the alcoholic liver is combined by orderly matching certain natural extracts with determined components and clear efficacies according to a plurality of principles of traditional Chinese medicine treatment based on syndrome differentiation and modern medicine.

The invention can run through the whole process of alcoholic liver treatment, treats both principal and secondary aspects of diseases, is not easy to relapse, is safe and reliable, has no obvious toxic and side effects, is convenient for patients to insist on taking for a long time, has no adverse reaction for the patients after taking the medicine for years, and tracks the blood examination to be normal.

The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.

The traditional Chinese medicine composition has remarkable effect of treating alcoholic liver, and clinical experiment results show that the prescription is used for treatment, one dose is taken every day, 100 ml of water is decocted, the dose is divided into two parts, one part is taken in the morning and at night, one month is taken as a treatment course, the effect is obviously improved after one treatment course, and the treatment course is basically cured after two to four treatment courses. The cure rate is 96 percent, and the total effective rate is 100 percent.

The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for sobering up and treating alcoholic liver, which comprises oral liquid, tablets, capsules, pills and the like, preferably the dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.

The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.

The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.

Claims

1. The traditional Chinese medicine for sobering up and treating alcoholic liver is characterized by comprising the following raw material medicines in parts by weight: 4.5-9 parts by weight of ginseng; 9-18 parts by weight of kudzu root, hovenia dulcis thunb, bupleurum chinense and dandelion root; 15-30 parts of kalimeris indica.

2. The traditional Chinese medicine for sobering up and treating alcoholic liver as claimed in claim 1, which is characterized by comprising the following raw material medicines in parts by weight: 9 parts of ginseng; 18 parts by weight of kudzu root, hovenia dulcis thunb, bupleurum chinense and dandelion root; and 30 parts of Indian kalimeris herb.

3. An oral preparation for sobering and treating alcoholic liver, which is prepared from the Chinese medicinal composition as claimed in any one of claims 1 or 2.

4. The oral preparation for sobering and treating alcoholic liver as claimed in claim 3, which comprises oral liquid, tablet, capsule and pill, preferably oral liquid and tablet.