CN113181258A - A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea - Google Patents

A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea Download PDF

Info

Publication number
CN113181258A
CN113181258A CN202110687964.8A CN202110687964A CN113181258A CN 113181258 A CN113181258 A CN 113181258A CN 202110687964 A CN202110687964 A CN 202110687964A CN 113181258 A CN113181258 A CN 113181258A
Authority
CN
China
Prior art keywords
parts
amenorrhea
dysmenorrhea
irregular menstruation
traditional chinese
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202110687964.8A
Other languages
Chinese (zh)
Inventor
仲崇允
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN113181258A publication Critical patent/CN113181258A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicine for treating irregular menstruation, dysmenorrhea and amenorrhea, which is prepared from the following raw material medicines in parts by weight: eighteen symptoms, large-lung meridian grass, Chinese redbud bark, asiatic toddalia root, herba hyperici japonici, radix rubiae Yunnanensis, sargentgloryvine stem, morinda officinalis, herba cistanche, radix cynanchi glaucescentis and radix achyranthis bidentatae.

Description

A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating irregular menstruation, dysmenorrhea and amenorrhea.
Background
Menoxenia, a common gynecological disease, is manifested as abnormal menstrual cycle or bleeding volume, accompanied by abdominal pain and general symptoms before and during menstruation.
It is called as menstrual abdominal pain or dysmenorrhea when it occurs around or just during menstrual period, such as pain in the lower abdomen and lumbosacral region, which is accompanied by pale complexion, sweating, nausea, vomiting, cold limbs and syncope, which affects work and life and is attacked by menstrual cycle.
Amenorrhea refers to a pathological condition in which the woman has not yet started menstruation or has been interrupted for more than 3 months after 18 years of age. Amenorrhea is the external manifestation of pathophysiological changes in the female body caused by various diseases, and is a clinical symptom.
At present, no specific medicine for treating irregular menstruation, dysmenorrhea and amenorrhea exists.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for treating irregular menstruation, dysmenorrhea and amenorrhea, can effectively improve or even eliminate the clinical symptoms of patients, and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
The invention provides a traditional Chinese medicine for treating irregular menstruation, dysmenorrhea and amenorrhea, which is prepared from the following raw material medicines in parts by weight: 5-10 parts of morinda officinalis; eighteen symptoms, large-lung-grass and Chinese redbud bark 6-12 parts by weight; 9-18 parts of asiatic toddalia root, sweet potato vine and sargentgloryvine stem; 15-30 parts of herba hyperici japonici, radix rubiae Yunnanensis, radix achyranthis bidentatae and herba cistanche deserticola.
In a preferred embodiment, the traditional Chinese medicine composition for treating irregular menstruation, dysmenorrhea and amenorrhea consists of the following raw material medicines in parts by weight: 10 parts of morinda officinalis; eighteen symptoms, large-lung-grass and Chinese redbud bark 12 weight parts; 18 parts of asiatic toddalia root, sweet potato vine and sargentgloryvine stem; 30 parts of herba hyperici japonici, radix rubiae Yunnanensis, radix achyranthis bidentatae and herba cistanche deserticola.
Wherein, eighteen symptoms: pungent and warm in flavor. The liver meridian entered is mainly used for expelling wind and clearing away cold, and promoting blood circulation to restore menstrual flow; relieving swelling and pain. The research finds that the medicine has good curative effect on irregular menstruation, dysmenorrheal and amenorrhea.
Radix et rhizoma Rhei: slightly bitter, astringent and mild in taste. Clear heat and remove dampness, activate blood and regulate menstruation. The research finds that the medicine has good curative effect on irregular menstruation, dysmenorrheal and amenorrhea.
Herb of Bupleurum: 2, pungent taste; sweet; mild in nature. Entering the lung; the liver meridian. Dispelling pathogenic wind and relieving exterior syndrome; resolving phlegm and relieving cough; promoting blood circulation to regulate menstruation. The research finds that the medicine has good curative effect on irregular menstruation, dysmenorrheal and amenorrhea.
Rubia yunnanensis: sweet; slightly bitter and warm. It enters liver meridian. Promoting blood circulation and relaxing muscles and tendons; removing blood stasis and promoting tissue regeneration; regulating qi and blood. Researches show that the medicine has good curative effects on irregular menstruation, dysmenorrheal, amenorrhea and postpartum arthralgia.
Root of Toddalia asiatica: pungent, slightly bitter and warm in flavor. Disperse blood stasis, stop bleeding, dispel wind, remove dampness, relieve swelling and remove toxicity. The research finds that the medicine has good curative effect on irregular menstruation, dysmenorrheal and amenorrhea.
And (3) Marsdenia tenacissima: is bitter in taste; slightly bitter; and (4) temperature. Liver diseases entering; the stomach meridian. Promoting blood circulation to regulate menstruation; to enrich the blood and relax the muscles and joints. Researches show that the Chinese medicinal composition has good curative effects on irregular menstruation, dysmenorrheal, amenorrhea and postpartum blood deficiency.
Sargentgloryvine stem: bitter and astringent, entering large intestine and liver meridian. Clearing away heat and toxic material, dispelling wind and eliminating carbuncle, promoting blood circulation and dredging collaterals. The research finds that the medicine has good curative effect on irregular menstruation, dysmenorrheal and amenorrhea.
Chinese redbud bark: bitter and mild in taste. Promoting blood circulation, dredging channels, relieving swelling and pain, and removing toxic substance. The research finds that the medicine has good curative effect on irregular menstruation, dysmenorrheal and amenorrhea. It is contraindicated for pregnant women.
Sweet fruit vine: is bitter in taste; and (6) cooling. Promoting blood circulation to regulate menstruation; dispelling wind and eliminating dampness. Researches show that the Chinese medicinal composition has good curative effects on irregular menstruation, dysmenorrheal, amenorrhea and postpartum abdominal pain.
Morinda officinalis: sweet, pungent and slightly warm. It enters kidney and liver meridians. Tonify kidney yang, strengthen tendons and bones, dispel wind-damp. Researches show that the traditional Chinese medicine composition has good curative effects on abnormal menstruation, dysmenorrheal and amenorrhea caused by cold uterus.
Herba Boschniakiae Rossicae: sweet in taste; salty; and (4) temperature. Invigorating kidney and strengthening yang; loosening bowel to relieve constipation; stopping bleeding. Researches show that the traditional Chinese medicine composition has good curative effects on abnormal menstruation, dysmenorrheal and amenorrhea caused by cold uterus.
The Chinese medicine is prepared from Chinese traditional herbal medicines, and is a Chinese medicine for effectively treating irregular menstruation, dysmenorrheal and amenorrhea by orderly matching certain natural extracts with determined components and clear effects according to a plurality of principles of traditional Chinese medicine dialectical treatment and modern medicine.
The traditional Chinese medicine can be used for treating irregular menstruation, dysmenorrhea and amenorrhea in the whole process of irregular menstruation, dysmenorrhea and amenorrhea treatment, one dose of the medicine is decocted with 100 ml of water for one day and is divided into two parts, and the medicine is taken in the morning and evening respectively, so that the effects of treating irregular menstruation, dysmenorrhea and amenorrhea are remarkable, the treatment on both symptoms and root causes is quick, the cure rate is high, relapse is not easy, the medicine is safe and reliable, no obvious toxic or side reaction is caused, the medicine is convenient for a patient to insist on taking for a long time, the patient does not have any adverse reaction after taking the medicine for many years, and the blood examination is normally tracked.
The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.
The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for treating irregular menstruation, dysmenorrhea and amenorrhea, the oral preparation comprises oral liquid, tablets, capsules, pills and the like, preferably the dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.
The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.
The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.

Claims (4)

1. The traditional Chinese medicine for treating irregular menstruation, dysmenorrhea and amenorrhea is characterized by comprising the following raw material medicines in parts by weight: 5-10 parts of morinda officinalis; eighteen symptoms, large-lung-grass and Chinese redbud bark 6-12 parts by weight; 9-18 parts of asiatic toddalia root, sweet potato vine and sargentgloryvine stem; 15-30 parts of herba hyperici japonici, radix rubiae Yunnanensis, radix achyranthis bidentatae and herba cistanche deserticola.
2. The traditional Chinese medicine for treating irregular menstruation, dysmenorrhea and amenorrhea according to claim 1, which is characterized by comprising the following raw material medicines in parts by weight: 10 parts of morinda officinalis; eighteen symptoms, large-lung-grass and Chinese redbud bark 12 weight parts; 18 parts of asiatic toddalia root, sweet potato vine and sargentgloryvine stem; 30 parts of herba hyperici japonici, radix rubiae Yunnanensis, radix achyranthis bidentatae and herba cistanche deserticola.
3. An oral preparation for treating irregular menstruation, dysmenorrhea and amenorrhea, which is prepared from the traditional Chinese medicine composition of any one of claims 1 or 2.
4. The oral preparation for treating irregular menstruation, dysmenorrhea and amenorrhea according to claim 3, which is prepared from oral liquid, tablets, capsules and pills, preferably oral liquid and tablets.
CN202110687964.8A 2020-06-27 2021-06-22 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea Withdrawn CN113181258A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010593430.4A CN111643561A (en) 2020-06-27 2020-06-27 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea
CN2020105934304 2020-06-27

Publications (1)

Publication Number Publication Date
CN113181258A true CN113181258A (en) 2021-07-30

Family

ID=72341254

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202010593430.4A Pending CN111643561A (en) 2020-06-27 2020-06-27 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea
CN202110687964.8A Withdrawn CN113181258A (en) 2020-06-27 2021-06-22 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN202010593430.4A Pending CN111643561A (en) 2020-06-27 2020-06-27 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea

Country Status (1)

Country Link
CN (2) CN111643561A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643561A (en) * 2020-06-27 2020-09-11 仲崇允 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643561A (en) * 2020-06-27 2020-09-11 仲崇允 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111643561A (en) * 2020-06-27 2020-09-11 仲崇允 A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea

Also Published As

Publication number Publication date
CN111643561A (en) 2020-09-11

Similar Documents

Publication Publication Date Title
CN106266463B (en) Traditional Chinese medicine composition for treating hyperuricemia and application thereof
CN113181258A (en) A Chinese medicinal composition for treating menoxenia, dysmenorrhea, and amenorrhea
CN113318191A (en) A Chinese medicinal composition for treating male infertility, sexual impotence, and premature ejaculation
CN112933173A (en) Traditional Chinese medicine composition for treating prostatitis
CN111529665A (en) A Chinese medicinal composition for treating angiitis and varicosis
CN109078157A (en) A kind of anti-tumor drug and preparation method thereof
CN111714601A (en) A Chinese medicinal composition for treating fungal infection
CN106822674B (en) Pharmaceutical composition for treating hyperthyroidism, preparation containing pharmaceutical composition, preparation method and application of pharmaceutical composition
CN111759946A (en) Traditional Chinese medicine composition for treating hernia
CN101028421A (en) Chinese medicine for treating chronic kidney failure
CN105663850A (en) Traditional Chinese medicine composition for treating oral ulcer
CN113304227A (en) Traditional Chinese medicine composition for treating neurasthenia and insomnia
CN111700951A (en) Chinese medicinal composition for treating abdominal mass
CN113476512A (en) A Chinese medicinal composition for treating hemorrhoid, proctoptosis and anal fistula
CN111714548A (en) Traditional Chinese medicine composition for treating cervicitis
CN111759960A (en) Traditional Chinese medicine composition for miscarriage prevention
CN111658697A (en) Traditional Chinese medicine composition for treating chronic enteritis
CN113599423A (en) Traditional Chinese medicine composition for treating anemia
CN113425816A (en) Traditional Chinese medicine composition for promoting lactation
CN111759900A (en) Traditional Chinese medicine composition for treating uterine prolapse
CN116077568A (en) Traditional Chinese medicine composition for treating abdominal mass
CN112426456A (en) A Chinese medicinal composition for treating AIDS
CN111759925A (en) A Chinese medicinal composition for treating adnexitis and pelvic inflammatory disease
CN111759908A (en) Traditional Chinese medicine composition for treating urticaria
CN111419974A (en) Traditional Chinese medicine composition for treating constipation

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20210730