CN102883713B - 耐醇型制剂 - Google Patents

耐醇型制剂 Download PDF

Info

Publication number
CN102883713B
CN102883713B CN201180023415.5A CN201180023415A CN102883713B CN 102883713 B CN102883713 B CN 102883713B CN 201180023415 A CN201180023415 A CN 201180023415A CN 102883713 B CN102883713 B CN 102883713B
Authority
CN
China
Prior art keywords
weight
amount
dosage form
film former
granule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180023415.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN102883713A (zh
Inventor
伊哈勃·哈米德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cima Labs Inc
Original Assignee
Cima Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cima Labs Inc filed Critical Cima Labs Inc
Publication of CN102883713A publication Critical patent/CN102883713A/zh
Application granted granted Critical
Publication of CN102883713B publication Critical patent/CN102883713B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
CN201180023415.5A 2010-05-11 2011-05-09 耐醇型制剂 Expired - Fee Related CN102883713B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33352110P 2010-05-11 2010-05-11
US61/333,521 2010-05-11
PCT/US2011/035767 WO2011143118A2 (en) 2010-05-11 2011-05-09 Alcohol-resistant formulations

Publications (2)

Publication Number Publication Date
CN102883713A CN102883713A (zh) 2013-01-16
CN102883713B true CN102883713B (zh) 2016-08-03

Family

ID=44344024

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180023415.5A Expired - Fee Related CN102883713B (zh) 2010-05-11 2011-05-09 耐醇型制剂

Country Status (10)

Country Link
US (2) US20130202705A1 (enExample)
EP (1) EP2568969A2 (enExample)
JP (1) JP5894720B2 (enExample)
CN (1) CN102883713B (enExample)
AU (1) AU2011253216B2 (enExample)
CA (1) CA2798700C (enExample)
IL (1) IL222637A (enExample)
MX (1) MX2012013021A (enExample)
NZ (1) NZ603531A (enExample)
WO (1) WO2011143118A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
CN103893146A (zh) * 2012-12-25 2014-07-02 天津药物研究院 含福多司坦缓释剂型
WO2014197744A1 (en) * 2013-06-05 2014-12-11 Synchroneuron, Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
US9561187B1 (en) * 2014-02-03 2017-02-07 CMAX Technologies, Inc. Sustained release metoprolol formulations
DK3164117T3 (da) 2014-07-03 2023-12-04 SpecGx LLC Misbrugssikre formuleringer med øjeblikkelig frigivelse omfattende ikke-cellulose-polysaccharider
US20180344649A1 (en) 2015-09-29 2018-12-06 Acorda Therapeutics, Inc. Sustained release compositions of 4-aminopyridine
WO2017145146A1 (en) 2016-02-25 2017-08-31 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
AR113993A1 (es) 2017-12-21 2020-07-08 Faes Farma Sa Formulación una vez al día de hidrosmina
CN110812337B (zh) * 2018-08-08 2022-04-12 上海宣泰医药科技股份有限公司 一种通过流化床制粒法制备氨基己酸片剂的方法
CN110812332B (zh) * 2018-08-10 2022-09-02 北京普德康利医药科技发展有限公司 一种双氯芬酸钠咽部滞留颗粒
US11478426B2 (en) 2018-09-25 2022-10-25 SpecGx LLC Abuse deterrent immediate release capsule dosage forms
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311582A1 (en) * 1987-10-08 1989-04-12 Aktiebolaget Hässle Pharmaceutical preparation with extended release of a dihydropyridine and a beta-adrenoreceptor antagonist and a process for the preparation thereof
US20070009598A1 (en) * 2003-10-10 2007-01-11 Ethypharm Sustained-release microgranules containging gingko biloba extract and the process for manufacturing these

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178878A (en) 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
US5223264A (en) 1989-10-02 1993-06-29 Cima Labs, Inc. Pediatric effervescent dosage form
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US20070092573A1 (en) * 2005-10-24 2007-04-26 Laxminarayan Joshi Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist
WO2007048223A2 (en) * 2005-10-25 2007-05-03 Pharmascience Inc. A gastric retention drug delivery system
US20080069891A1 (en) * 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
JP2008007293A (ja) * 2006-06-30 2008-01-17 Komori Corp 搬送装置
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
DK2200593T5 (en) * 2007-09-13 2016-12-12 Cima Labs Inc Hog-resistant pharmaceutical formulation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311582A1 (en) * 1987-10-08 1989-04-12 Aktiebolaget Hässle Pharmaceutical preparation with extended release of a dihydropyridine and a beta-adrenoreceptor antagonist and a process for the preparation thereof
US20070009598A1 (en) * 2003-10-10 2007-01-11 Ethypharm Sustained-release microgranules containging gingko biloba extract and the process for manufacturing these

Also Published As

Publication number Publication date
JP2013526521A (ja) 2013-06-24
NZ603531A (en) 2014-08-29
AU2011253216A1 (en) 2012-11-29
EP2568969A2 (en) 2013-03-20
US20130202705A1 (en) 2013-08-08
CA2798700C (en) 2018-08-21
WO2011143118A2 (en) 2011-11-17
MX2012013021A (es) 2012-12-17
CN102883713A (zh) 2013-01-16
JP5894720B2 (ja) 2016-03-30
AU2011253216B2 (en) 2016-10-20
WO2011143118A3 (en) 2012-07-05
IL222637A0 (en) 2012-12-31
US20190133924A1 (en) 2019-05-09
IL222637A (en) 2017-04-30
CA2798700A1 (en) 2011-11-17

Similar Documents

Publication Publication Date Title
CN102883713B (zh) 耐醇型制剂
CN102770127B (zh) 抗滥用制剂
US9474721B2 (en) Abuse-resistant formulations
CN102325526B (zh) 延长释放的药物制剂
JP5052602B2 (ja) 制御用量薬物送達システム
EP2405900A2 (en) A novel sustained release composition of compounds selected from the class of centrally acting muscle relaxants
US8927025B2 (en) Alcohol-resistant metoprolol-containing extended-release oral dosage forms
CN101472561A (zh) 去氧肾上腺素脉冲释放制剂和药物组合物
US20130171256A1 (en) Alcohol-resistant extended release dosage forms comprising venlafaxine
Dulin Oral targeted drug delivery systems: enteric coating
JP5919173B2 (ja) 徐放性塩酸アンブロキソール口腔内崩壊錠
WO2009135520A1 (en) Sustained release microtablets comprising tolterodine tartrate

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160803

Termination date: 20180509

CF01 Termination of patent right due to non-payment of annual fee