Summary of the invention
The technical problem to be solved in the present invention is: overcome and only have at present the HPV vaccine to prevent and can not treat that HPV infects and existing medicine and physiotherapy are treated the problem of not good enough, the easy recurrence of cervical erosion curative effect, damaged tissue organ, provide a kind of and the HPV sun is turned out cloudy and effect a radical cure cervical erosion, medicine simple, that have no side effect without high and low temperature, to human body and preparation method thereof.
In order to solve the problems of the technologies described above, the present invention proposes following technical scheme: a kind of human papillomavirus's of making sun is turned out cloudy and is treated the medicine of cervical erosion, and it comprises following component and content (percentage by weight):
Exocarpium Juglandis Immaturus 30%-40%;
Radix Arnebiae (Radix Lithospermi) 10%-15%;
Ramulus Mori ash 5%-10%;
Cortex Phellodendri 5%-10%;
Radix Sophorae Flavescentis 7%-10%;
Fructus Cnidii 7%-10%;
Methylcellulose 2-5%;
Agar 2-5%;
Arabic gum 8-12%.
The further restriction of technique scheme is: this medicine comprises following component and content (percentage by weight): Exocarpium Juglandis Immaturus 30%; Radix Arnebiae (Radix Lithospermi) 15%; Ramulus Mori ash 10%; Cortex Phellodendri 10%; Radix Sophorae Flavescentis 10%; Fructus Cnidii 10%; Methylcellulose 5%; Agar 2%; Arabic gum 8%.
The further restriction of technique scheme is: this medicine comprises following component and content (percentage by weight): Exocarpium Juglandis Immaturus 40%; Radix Arnebiae (Radix Lithospermi) 10%; Ramulus Mori ash 7%; Cortex Phellodendri 5%; Radix Sophorae Flavescentis 9.5%; Fructus Cnidii 9.5%; Methylcellulose 2%; Agar 5%; Arabic gum 12%.
The further restriction of technique scheme is: this medicine comprises following component and content (percentage by weight): Exocarpium Juglandis Immaturus 39%; Radix Arnebiae (Radix Lithospermi) 14%; Ramulus Mori ash 5%; Cortex Phellodendri 9%; Radix Sophorae Flavescentis 7%; Fructus Cnidii 7%; Methylcellulose 4%; Agar 4%; Arabic gum 11%.
In order to solve the problems of the technologies described above, the present invention proposes following technical scheme: a kind of turn out cloudy preparation method of medicine for the treatment of cervical erosion of the above-mentioned human papillomavirus's of making sun for preparing, it comprises the steps:
Step 1: pulverize, get Exocarpium Juglandis Immaturus, Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash, Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii according to above-mentioned content, utilize to add mechanical force, the cohesiveness between the destruction material molecule is that the piece grain of medicine reduces, and surface area is increased, and is prepared into medicinal powder;
Step 2: leach, the medicinal powder that taking-up step 1 prepares places container with lid to add the 1000ml purified water, sealing lid is jolting constantly, flooded 3-5 days in the room temperature dark place, effective ingredient is fully leached, get upper strata liquid and filter with cloth, get in the filtrate adding vaporizer and be concentrated into 900ml with evaporation;
Step 3: emulsifying, the concentrated solution that step 2 is obtained adds methylcellulose, agar, the arabic gum of above-mentioned content, carries out forming gel after the emulsifying;
Step 4: fill to administrator, seals the gel fill, and get final product.
Compared with prior art, the present invention has following beneficial effect: this product can make the HPV sun turn out cloudy, and effectively prevents the generation of cervical cancer, and can effect a radical cure cervical erosion, recover cervix uteri form, function, can once kill varicella zoster virus, pain relieving, antiinflammation are arranged.This product externally treating herpes zoster can be removed virus fast, and obvious analgesic effect is arranged.
The specific embodiment
A kind of human papillomavirus's of making sun is turned out cloudy and is treated the medicine of cervical erosion, and it comprises following component and content (percentage by weight):
Exocarpium Juglandis Immaturus 30%-40%;
Radix Arnebiae (Radix Lithospermi) 10%-15%;
Ramulus Mori ash 5%-10%;
Cortex Phellodendri 5%-10%;
Radix Sophorae Flavescentis 7%-10%;
Fructus Cnidii 7%-10%;
Methylcellulose 2-5%;
Agar 2-5%;
Arabic gum 8-12%.
(please note that I have revised numerical range here, please your department be confirmed whether to agree to revise?)
The preparation method of said medicine comprises the steps:
Step 1: pulverize, get Exocarpium Juglandis Immaturus, Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash, Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii according to above-mentioned content, utilize to add mechanical force, the cohesiveness between the destruction material molecule is that the piece grain of medicine reduces, and surface area is increased, and is prepared into medicinal powder.
Step 2: leach, the medicinal powder that taking-up step 1 prepares places container with lid to add the 1000ml purified water, and sealing lid is jolting constantly, floods 3-5 days in the room temperature dark place, and effective ingredient is fully leached, and gets upper strata liquid and filters with cloth.Get in the filtrate adding vaporizer and be concentrated into 900ml with evaporation.
Step 3: emulsifying, the concentrated solution that step 2 is obtained adds methylcellulose, agar, the arabic gum of above-mentioned content, carries out forming gel after the emulsifying.
Step 4: fill to administrator, seals the gel fill, and get final product.
The using method of said medicine is: (1) takes out the administrator protecgulum, opens the medicated cap lid; (2) lie on the back, the administrator main body slowly sent into the vagina depths, as feel uncomfortable or obstruction is arranged, namely stop to advance, protecgulum as push rod gently with the disposable injection vagina of medicine; (3) extract gently administrator, kept back floating position 15 minutes.
Medicine of the present invention is the sepia gel, take Exocarpium Juglandis Immaturus as monarch drug, with Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash compatibility, the heat-clearing and toxic substances removing double effects is arranged, with Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii three flavor is used for the treatment of the skin ulcer toxic swelling of itching for ministerial drug, does not hold back after routed, has more heat clearing away, detoxifcation, anticorrosion, granulation promoting four effects.
Exocarpium Juglandis Immaturus, Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash, Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii ginseng have heat clearing away, sterilization, anticorrosion, sterilization, antiviral, antitumaous effect, and merceration does not damage its various sterilization antiviral functions.After mixing slough virus, antibacterial there are stronger removing power and can stimulate tissue regeneration, to removing HPV and the good curative effect of radical cure cervical erosion.
Compendium of Material Medica is being put down in writing blue or green Semen Juglandis and is being had analgesic effect.In proved recipe of traditional Chinese medicine, Exocarpium Juglandis Immaturus can be used for treating the diseases such as skin pruritus and pain Exocarpium Juglandis Immaturum, and Exocarpium Juglandis Immaturus is steep in wine, and can be used for the treating the liver peratodynia, gastralgia, acute and chronic stomachache.The blue or green Semen Juglandis of domestic and international usefulness among the people the 1950's steep in wine agent treatment stomachache, dysmenorrhea, cancer pain etc. to replace the analgesic such as morphine, tinctura opii, have been received good analgesic effect.Contain multiple bioactive ingredients in the Exocarpium Juglandis Immaturus, before its immaturity, contain vitamin C.Adopting BSLB(brine shrimp lethelity bioassay) method active component that Exocarpium Juglandis Immaturus the is extracted result that carries out Preliminary screening shows: its ethyl acetate extract all has obvious cytotoxicity, is expected further research and makes new antitumor drug.
The present invention uses traditional Chinese medicine theory, and is antitoxin as monarch drug take the Exocarpium Juglandis Immaturus pain relieving, adds Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash removing heat from blood, the poison of invigorating blood circulation, purify the blood, controls skin ulcer and itch, and more is accompanied by Cortex Phellodendri, Radix Sophorae Flavescentis, and Fructus Cnidii sterilization antiinflammatory has embodied the powerful effect of Chinese medicine.These six kinds of compatibility of drugss, between without eighteen incompatible medicaments, nineteen medicaments of mutual restraint phenomenon.More because this medicine compatibility, implementation medicine for external use 10-15 service time minute, without the systemic Absorption effect, so safety, have no side effect.
Medicine of the present invention can effect a radical cure cervical erosion, recovers cervix uteri form, function, selectively removes virus and slough, enhancer cervix uteri regeneration capacity.Herpes zoster is controlled in this product external, condyloma acuminatum, and verruca plana etc. can be removed the viruses such as HSV, HPV fast, and obvious analgesic effect is arranged.Medicine of the present invention is that the modulation of Purely natural edible plant forms, and human body is had no side effect.
The below introduces several concrete Preparation Examples
Embodiment one
Component |
Weight (gram) |
Percentage ratio (%) |
Exocarpium Juglandis Immaturus |
300 |
30% |
Radix Arnebiae (Radix Lithospermi) |
150 |
15% |
The Ramulus Mori ash |
100 |
10% |
Cortex Phellodendri |
100 |
10% |
Radix Sophorae Flavescentis |
100 |
10% |
Fructus Cnidii |
100 |
10% |
Methylcellulose |
50 |
5% |
Agar |
20 |
2% |
Arabic gum |
80 |
8% |
Gross weight |
1000 |
100% |
Pulverize: get Exocarpium Juglandis Immaturus, Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash, Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii according to the weight of upper table, utilize to add mechanical force, the cohesiveness between the destruction material molecule is that the piece grain of medicine reduces, and surface area is increased, and is prepared into medicinal powder.
Leach: the medicinal powder that taking-up step 1 prepares places container with lid to add the 1000ml purified water, sealing lid is jolting constantly, floods 3-5 days in the room temperature dark place, and effective ingredient is fully leached, get upper strata liquid and filter with cloth, get in the filtrate adding vaporizer and be concentrated into 900ml with evaporation.
Emulsifying: the concentrated solution that step 2 is obtained adds upper methylcellulose, agar, the arabic gum of showing weight, carries out forming gel after the emulsifying.
Fill: the gel fill to administrator, is sealed, and get final product.
Embodiment two
Component |
Weight (gram) |
Percentage ratio (%) |
Exocarpium Juglandis Immaturus |
400 |
40% |
Radix Arnebiae (Radix Lithospermi) |
100 |
10% |
The Ramulus Mori ash |
70 |
7% |
Cortex Phellodendri |
50 |
5% |
Radix Sophorae Flavescentis |
95 |
9.5% |
Fructus Cnidii |
95 |
9.5% |
Methylcellulose |
20 |
2% |
Agar |
50 |
5% |
Arabic gum |
120 |
12% |
Gross weight |
1000 |
100% |
Pulverize: get Exocarpium Juglandis Immaturus, Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash, Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii according to the weight of upper table, utilize to add mechanical force, the cohesiveness between the destruction material molecule is that the piece grain of medicine reduces, and surface area is increased, and is prepared into medicinal powder.
Leach: the medicinal powder that taking-up step 1 prepares places container with lid to add the 1000ml purified water, sealing lid is jolting constantly, floods 3-5 days in the room temperature dark place, and effective ingredient is fully leached, get upper strata liquid and filter with cloth, get in the filtrate adding vaporizer and be concentrated into 900ml with evaporation.
Emulsifying: the concentrated solution that step 2 is obtained adds upper methylcellulose, agar, the arabic gum of showing weight, carries out forming gel after the emulsifying.
Fill: the gel fill to administrator, is sealed, and get final product.
Embodiment three
Component |
Weight (gram) |
Percentage ratio (%) |
Exocarpium Juglandis Immaturus |
390 |
39% |
Radix Arnebiae (Radix Lithospermi) |
140 |
14% |
The Ramulus Mori ash |
50 |
5% |
Cortex Phellodendri |
90 |
9% |
Radix Sophorae Flavescentis |
70 |
7% |
Fructus Cnidii |
70 |
7% |
Methylcellulose |
40 |
4% |
Agar |
40 |
4% |
Arabic gum |
110 |
11% |
Gross weight |
1000 |
100% |
Pulverize: get Exocarpium Juglandis Immaturus, Radix Arnebiae (Radix Lithospermi), Ramulus Mori ash, Cortex Phellodendri, Radix Sophorae Flavescentis, Fructus Cnidii according to the weight of upper table, utilize to add mechanical force, the cohesiveness between the destruction material molecule is that the piece grain of medicine reduces, and surface area is increased, and is prepared into medicinal powder.
Leach: the medicinal powder that taking-up step 1 prepares places container with lid to add the 1000ml purified water, sealing lid is jolting constantly, floods 3-5 days in the room temperature dark place, and effective ingredient is fully leached, get upper strata liquid and filter with cloth, get in the filtrate adding vaporizer and be concentrated into 900ml with evaporation.
Emulsifying: the concentrated solution that step 2 is obtained adds upper methylcellulose, agar, the arabic gum of showing weight, carries out forming gel after the emulsifying.
Fill: the gel fill to administrator, is sealed, and get final product.
The below introduces the treatment situation of the part clinical patient that uses medicine of the present invention:
1. go into business so-and-so, woman, 38 years old, Jiangxi, native place, Shenzhen, address, dysmenorrhea always, menoxenia, the frequent pruritus of vagina, lower abdomen distending pain, urine urgency-frequency.Be diagnosed as moderate and severe cervical in 2009 and infect high-risk HPV virus.She has gone to a lot of hospitals, has used a lot of different therapeutic modalities, but always again and again can not cure fully.After half a year, symptom fades away through Drug therapy of the present invention, and hospital again examining report proves: the HPV positive has turned negative cervical erosion, recovers fully, and indices is all normal.
Lee so-and-so, woman, 29 years old, Guangdong, native place, the Guangzhou, address, consultation time on May 16th, 2010, waist and sacrum pain, the hypogastric region pendant is swollen, leucorrhea is undesired, and the people is very wan and sallow, checks that finding is cervical erosion and high-risk HPV viral infection, and further checks the precancerous lesion of confirming as cervical cancer.Through Drug therapy of the present invention, recovery from illness in three months.Follow up a case by regular visits to 2 years without recurrence.
History so-and-so, woman, 42 years old, Sichuan Province, native place, Guangzhou, address.On April 5th, 2009 is medical, and the gynecologial examination result: vaginal wall swelling, cervix uteri can contact the cervix uteri of enlargement apart from the about 3CM of vaginal orifice place, about cervix uteri diameter 6.2CM, and a large amount of purulent secretions.Cervix uteri is uneven, is graininess, and iodine test is negative, belongs to the severe uterine erosion.Remove examination in hospital behind Drug therapy two wheat harvesting periods of the present invention, the pleasantly surprised discovery of doctors for many years gynecological is healed, the cervical erosion rehabilitation, vagina becomes flexibly, obviously shrinks.
4. Zhu, woman, 24 years old, Changsha, native place, address Changsha.Do inspection to Hunan Province healthcare hospital for women ﹠ children in June, 2011, and HPV DNA detection value is 287.82Pg/ml, and cervix uteri, neck tube histopathology are diagnosed as: the squamous epithelial cancer that becomes between the fragmentation of (neck tube) small pieces meets the tired gland of CIN III level.(10 °) chronic cervicitis, special mess CIN II-III level companion viral infection.(2 ° 12 °) chronic cervicitis, special mess CIN II level companion viral infection.(4 °) chronic cervicitis.Treatment has now transferred CIN I level to through this patent product.
5, Ao so-and-so, the woman, 48 years old, Jiangxi, native place, the Guangzhou, address, consultation time on May 16th, 2011, the yellow-white leucorrhea more than ten years, dyspareunia, hemorrhage, the lower abdomen pendant is swollen, fat, facial black speck, is cervical erosion through many hospital diagnosis, fail to respond to any medical treatment.After Drug therapy of the present invention 50 days, it was clean to look into vagina, and cervical erosion disappears, the cervix uteri smooth surface, and the cervix uteri prolapsus disappears, and the cervix uteri reduced is to about the 3CM, and vagina contraction is good.Cure and follow up a case by regular visits to after 2 years, have no leucorrhea, have no recurrence.Facial melanin speckle also disappeared with Chinese medicine in 20 days.
6, Wu so-and-so, the woman, 32 years old, people from Hebei, native place, Beijing, address, consultation time on May 18th, 2009, hemorrhage when a large amount of yellow leucorrhea, stench, sexual intercourse are often arranged, through gynecologial examination, cervix uteri three degree are rotten to the corn.The physics treatment is done in private prosecution once many hospitals, sanguinous leukorrhea occurs again after one to two month upward swing is arranged.Through medicine liquid medicine treatment of the present invention recovery from illness in 65 days.After follow up a case by regular visits to 2 years without the recurrence.
7, the king so-and-so, woman, 34 years old, Sichuan Province, native place, the Guangzhou, address, consultation time on January 14th, 2010, main suit's vagina is bled for a long time, hemorrhage increasing when anemia, sexual intercourse, leucorrhoea grow in quantity, frowziness, the disappearance of colpedema wrinkle arm, mucosal bleeding, vagina elasticity disappear, and many hospitalizes are invalid.Through medicine liquid medicine treatment of the present invention recovery from illness in 68 days, follow up a case by regular visits to 2 years without recurrence.
8, military so-and-so, woman, 46 years old, Guangdong Province, native place, Shenzhen, address, consultation time: on January 12nd, 2008, check cervical erosion Ⅲ degree through the united family hospital, Shenzhen, gynecologial examination vulvovaginal redness, mucosal bleeding, the contracting of vagina flaccidity, cervical mucosa necrosis area 3x2CM.Through Drug therapy of the present invention recovery from illness in 58 days.
A large amount of healing statements of facts, medicine of the present invention has extraordinary curative effect for the treatment HPV positive and cervical erosion.
This product can make the HPV sun turn out cloudy, and effectively prevents the generation of cervical cancer, and can effect a radical cure cervical erosion, recovers cervix uteri form, function, can once kill varicella zoster virus, and pain relieving, antiinflammation are arranged.This product externally treating herpes zoster can be removed virus fast, and obvious analgesic effect is arranged.