CN106668295A - Externally-used medicine for treating psoriasis, and preparation method of externally-used medicine - Google Patents

Abstract

The invention belongs to the field of traditional Chinese medicine preparations, aiming at providing an externally-used medicine for treating psoriasis according to the know mechanism of the psoriasis of traditional Chinese medicine. The externally-used medicine is prepared from the following components in parts by mass: 12-20g of Japanese dock root, 12-20g of cortex pseudolaricis, 0.3-1g of semen hydnocarpi anthelmiticae, 10-45g of radix rehmanniae, 2-5g of centipede, 0.06-0.18g of large blister beetle, 3-30g of radix et rhizoma rhei, 1-3g of calomel, 1-6g of alumen, 8-18g of fructus toosendan, 3-8g of pericarpium zanthoxyli, 8-16g of radix sophorae flavescentis, 8-16g of cortex moutan, 3-12g of folium artemisiae argyi, 5-16g of fructus cnidii, 10-26g of cortex dictamni and 6-16g of cortex erythrinae. The medicine provided by the invention is a good traditional Chinese medicine formula.

Description

One kind treats psoriasic external used medicine and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to its one kind treats psoriasic external used medicine, particularly for ox The field of the external used medicine that psoriasis patient uses and preparation method thereof.

Background technology

Psoriasis, equivalent to white scar, white shell sore, psoriasis, snake lice, the stubborn dermatitis etc. of the traditional Chinese medical science, is a kind of chronic inflammatory, non-sense Metachromia skin disease.The disease passes through slow, with tendency of recurrence.Its pathogenesis may with infection, dysbolism, immunologic function, Heredity and its factor such as spirit are relevant, but not yet illustrate completely so far, and the traditional Chinese medical science thinks that the generation of this disease and blood-head, blood be dry, blood stasis Etc. relevant.Psoriatic's throughout world various regions, different nationalities, sex, age can fall ill.According to the literature, it is psoriasic The incidence of disease accounts for the 0.1%~3% of world population, and yellow's incidence of disease is 0.1%~0.3%, incidence of disease white race of the disease in crowd People takes second place apparently higher than yellow, black race, and by the end of the end of the year 2000, China psoriatic increased one than 1994 Times；The illness rate in the north is higher than again south, and China psoriatic is at least 1,300,000~4,000,000 or so.Psoriasis can be divided into Homeliness type, pustule type, arthropathica, erythrodermic, most commonly seen with homeliness type psoriasis, clinical manifestation is with the white scales of skin that peel off, thin Film phenomenon, petechial hemorrhage are characterized.Although psoriasis does not threaten the life security of people, the disease because its is chronic, touching repeatedly, Obstinate refractory, high recurrence rate, the social life for having a strong impact on patient, cause great body and psychological pain, to patient Physically and mentally healthy influence it is very big.Simultaneously as the sick recurrent exerbation, need to often treat repeatedly, also heavy economy is brought to patient Burden.

So, with regard to how to find one kind can effective antipsoriatics thing, be our current problems in urgent need to solve.

The content of the invention

With continuing to develop for China's traditional Chinese medicine, in treatment psoriasis, people gradually appreciate Chinese traditional treatment Psoriasic advantage, and the advantage such as good effect, instant effect, toxic and side effect be small over the course for the treatment of, for existing western medical treatment ox The present situation of psoriasis, it is to provide one kind to treat psoriasic external used medicine that the purpose of the present invention is, to solve psoriatic's morning Day restorative problem.The medicine is that, with common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can have The above-mentioned psoriasis of effect treatment.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats psoriasic outer With medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

12~20g of rumex root, 12~20g of Golden Larch Bark, 0.3~1g of chaulmoogra benevolence, 10~45g of radix rehmanniae recen, 2~5g of centipede, Chinese blister beetle 0.06~0.18g, 3~30g of rheum officinale, 1~3g of calomel mercurous chloride, 1~6g of alum, 8~18g of Fructus meliae toosendan, 3~8g of Chinese prickly ash, 8~16g of kuh-seng, 8~16g of moutan bark, 3~12g of folium artemisiae argyi, 5~16g of frutus cnidii, 10~26g of the root bark of shaggy-fruited dittany, 6~16g of erythrina bark.

One kind treats psoriasic external used medicine and preparation method thereof, it is characterised in that each component of the medicine and Its mass parts is than as follows：

13~17g of rumex root, 13~17g of Golden Larch Bark, 0.4~0.8g of chaulmoogra benevolence, 12~40g of radix rehmanniae recen, 3~4.5g of centipede, 0.08~0.16g of Chinese blister beetle, 5~26g of rheum officinale, 1.5~2.5g of calomel mercurous chloride, 2~5.5g of alum, 10~16g of Fructus meliae toosendan, 5~7g of Chinese prickly ash, 10~14g of kuh-seng, 10~14g of moutan bark, 5~11g of folium artemisiae argyi, 8~14g of frutus cnidii, 11~23g of the root bark of shaggy-fruited dittany, 8~14g of erythrina bark.

One kind treats psoriasic external used medicine and preparation method thereof, it is characterised in that the medicine of " preferred plan " Each component and its mass parts than as follows：

Rumex root 15g, Golden Larch Bark 15g, chaulmoogra benevolence 0.6g, radix rehmanniae recen 35g, centipede 4g, Chinese blister beetle 0.15g, rheum officinale 23g, calomel mercurous chloride 2.3g, alum 5g, Fructus meliae toosendan 14g, Chinese prickly ash 6g, kuh-seng 12g, moutan bark 12g, folium artemisiae argyi 10g, frutus cnidii 12g, root bark of shaggy-fruited dittany 20g, sea Paulownia skin 12g.

One kind treats psoriasic external used medicine and preparation method thereof, it is characterised in that methods described comprises the following steps It is prepared from：

A, above-mentioned raw materials Chinese medicine is picked into impurity, dust and drying after, it is more stand-by than being ground into coarse altogether according to mass parts；

B, the coarse medicine that will be crushed are contained to tying in cloth bag, while the cloth bag that will tie mouth is placed with the medicine device of lid In, add the medicinal alcohol that concentration is 70~75% appropriate, Mi Gai is stirred or shaken, and is impregnated 125 hours, is inclined after taking supernatant, then The secondary alcohol for adding 70~75% is appropriate, it is to be impregnated fully leached to active ingredient after, pull the cloth bag for containing medicine out, merge leaching Go out liquid, stand 12 hours, filtering gets product tincture dose medicament.

One kind treats psoriasic external used medicine and preparation method thereof, it is characterised in that the application method is：By tincture Final drug cotton swab is uniformly applied to site of disease, while rubbing 5~8 minutes, three times per day, the morning, noon and afternoon respectively apply ointment once, control Treating 2~3 months can recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine Record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Rumex root, nature and flavor：It is bitter, acid, cold in nature（It is cool）, it is slightly poisonous, with dampness removing, cholagogic, detumescence move back Huang, spleen benefiting and stimulating the appetite, purging intense heat, The effect of defaecation, antibacterial of expelling the heat-evil, for treating oxyhepatitis, chronic bronchitis, lung heat hemoptysis, haematemesis, nosebleed epistaxis, hemorrhoid blood, function Property uterine hemorrhage, leucopaenia purpura disease, big constipation, skin disease, anal inflammation, nameless sores or boils, stranguria with turbid discharge, jaundice, carbuncle swells, head Lice is considered to be worth doing in vain, scabies, stubborn dermatitis；

Golden Larch Bark, nature and flavor：Pungent, temperature, it is poisonous, with dispelling wind and eliminating dampness, desinsection is antipruritic the effect of, for treating mange, eczema, nerve Property various tinea cards such as dermatitis, ringworm of the body, tinea of feet and hands, favus of the scalp；

Chaulmoogra benevolence, nature and flavor：Taste is pungent, property heat, it is very toxic, with dispelling pathogenic wind and remove dampness, detoxicating and destroying parasites the effect of, belong to desinsection antipruritic, It is clinical main sick with lepra lepromatosa is controlled；

Radix rehmanniae recen, nature and flavor：It is sweet, bitter, cold in nature, the effect of with heat-clearing, cool blood, ying blood, high fever are entered for treating warm heat disease heat Coma, dry tongue are deep red；

Centipede, nature and flavor：Pungent, temperature, it is poisonous, with wind-dispelling, calm the frightened, attack poison, dissipating bind the effect of, for treating apoplexy, frightened epilepsy, broken wound The disease such as wind, pertussis, scrofula, tuberculosis, disease buildup block, sore swollen toxin, wind tinea, white bald, anal fistula, scald；

Chinese blister beetle, nature and flavor：Pungent, heat, it is very toxic, with Po Xue Xiao wei, work(poison phagedenoma, draw red foaming the effect of, for Zhi Liao wei lumps in the abdomen Lump, for many years stubborn dermatitis, scrofula, wart, ulcer are not burst, dislike the dead flesh of sore；

Rheum officinale, nature and flavor：It is bitter, cold, the effect of with real heat, broken stagnant, row hemostasis is rushed down, stagnated for treating real heat constipation, dyspepsia, Stomachache, acute appendicitis, acute infectious hepatitis, blood stasis is through closing, toothache, bleeding from five sense organs or subcutaneous tissue, acute conjunctivitis, external application are controlled burn and scald, are changed The diseases such as purulence skin disease, carbuncle swells sore；

Calomel mercurous chloride, nature and flavor：It is pungent, cold, it is poisonous, with desinsection, attack poison, rotten, antipruritic, eliminating the phlegm of dispelling, relieve oedema or abdominal distension through diuresis or purgation, defaecation the effect of, for controlling Treat that sore festers, mange pruigo, scrofula, syphilis, infantile malnutrition due to digestive disturbances or intestinalparasites sore, wine Zha nose, acne, anxious chronic infantile convulsion, phlegm are stopped up and breathes heavily inverse, oedema turgor, two Just it is unfavorable to wait disease；

Alum, nature and flavor：It is sour and astringent, cold, it is poisonous, the effect of hemostasis with eliminating the phlegm eliminating dampness, removing toxic substances desinsection, antidiarrheal, for treat apoplexy, Polyp, sore hemorrhoid in epilepsy, larynx numbness, mange wet sore, swollen ulcer drug, scald, aphthae, belepharitis ciliaris eye, Ting discharging ear, nose Pain, uterine bleeding, bleeding from five sense organs or subcutaneous tissue, bleeding due to trauma, the dysentery of chronic diarrhea nine, under band pruritus vulvae, prolapse of the anus, metroptosis；

Fructus meliae toosendan, nature and flavor：It is bitter, cold, it is poisonous, the effect of with except damp and hot, clearing away the liver-fire, analgesic, desinsection, for treating the heat jue heart Bitterly, hypochondriac pain, colic, abdominal pain due to enterositosis；

Chinese prickly ash, nature and flavor：Pungent, temperature, it is poisonous, the effect of with warming spleen and stomach for dispelling cold, dehumidifying, analgesic, desinsection, solution fish raw meat poison, for treating Having indigestion stop drink, trusted subordinate's crymodynia, vomiting, oh, cough with dyspnea, wind-cold-dampness arthralgia, diarrhea, dysentery, colic, dentalgia, roundworm disease, pinworm The diseases such as disease, pruritus vulvae, sore scabies；

Kuh-seng, nature and flavor：It is bitter, cold, the effect of with heat-clearing, eliminating dampness, desinsection, for treat toxic-heat and blood stasis, discharging fresh blood stool, jaundice, Leukorrhea with reddish discharge, infantile pneumonia, infantile malnutrition due to digestive disturbances or intestinalparasites, acute tonsillitis, anal fistula, prolapse of the anus, pruitus, scabies leprosy dislike sore, the erosion of vulva it is wet itch, scrofula Scrofula, scald, control outward trichomonas vaginitis；

Moutan bark, nature and flavor：It is arduous, cool, the effect of with heat-clearing, cool blood and blood, dispersing blood stasis, for treat heat invading xuefen, hair spot, Frightened epilepsy, tell, be defeated in battle, having blood in stool, hectic fever due to yin labor heat, Amenorrhea, abdominal mass, large carbuncle, flutter damage etc. disease；

Folium artemisiae argyi, nature and flavor：Acrid, bitter, warm, it is slightly poisonous, the effect of with eliminating cold to stop pain, warming channel for arresting bleeding, for treating few abdomen crymodynia, warp Cold uncomfortable, uterus cold infertile, haematemesis, bleeding from five sense organs or subcutaneous tissue, uterine bleeding pass through many, gestation hemorrhage, control pruitus outward, vinegar Chinese mugwort charcoal warming channel for arresting bleeding, are used for Deficient cold type bleeding；

Frutus cnidii, nature and flavor：Arduous, temperature, the effect of with warming kidney and enhancing yang, wind-dispelling, eliminating dampness, desinsection, for treating impotence in male, the moon The diseases such as capsule is wet to itch, woman's under band pruritus vulvae, infertile cold uterus, arthralgia pain due to rheumatism, mange wet sore；

The root bark of shaggy-fruited dittany, nature and flavor：It is bitter salty, cold, the effect of with wind-dispelling, eliminating dampness, heat-clearing, removing toxic substances, for treat wind-heat sore, mange, Itchy skin eruption, arthralgia pain due to rheumatism, jaundice；

Erythrina bark, nature and flavor：It is bitter, pungent, flat, the effect of with dispelling wind and eliminating dampness, channels sootheing and network vessel quickening, antipruritic desinsection, for treating rheumatism numbness Bitterly, the disease such as podomere contraction, traumatic injury, mange, eczema.

Medicine of the present invention is, based on the psoriasic principle of Chinese traditional treatment, to think from pharmacological action and its mechanism of action：With regard to ox Psoriasis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at above-mentioned psoriasis treatment, the medicine prepared using the formula Thing good drug efficacy, instant effect is a Chinese prescription treated both principal and secondary aspect of disease, and is particularly suitable for Clinical practice.With reference to tool of the invention Body implementation method is described in further detail：

Embodiment 1：

One kind treats psoriasic external used medicine, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

Rumex root 15g, Golden Larch Bark 15g, chaulmoogra benevolence 0.6g, radix rehmanniae recen 35g, centipede 4g, Chinese blister beetle 0.15g, rheum officinale 23g, calomel mercurous chloride 2.3g, alum 5g, Fructus meliae toosendan 14g, Chinese prickly ash 6g, kuh-seng 12g, moutan bark 12g, folium artemisiae argyi 10g, frutus cnidii 12g, root bark of shaggy-fruited dittany 20g, sea Paulownia skin 12g.

Embodiment 2：

One kind treats psoriasic external used medicine, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

It is rumex root 17g, Golden Larch Bark 17g, chaulmoogra benevolence 0.8g, radix rehmanniae recen 40g, centipede 4.5g, Chinese blister beetle 0.16g, rheum officinale 26g, light Powder 2.5g, alum 5.5g, Fructus meliae toosendan 16g, Chinese prickly ash 7g, kuh-seng 14g, moutan bark 14g, folium artemisiae argyi 11g, frutus cnidii 14g, the root bark of shaggy-fruited dittany 23g, erythrina bark 14g.

Embodiment 3：

One kind treats psoriasic external used medicine, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

Rumex root 20g, Golden Larch Bark 20g, chaulmoogra benevolence 1g, radix rehmanniae recen 45g, centipede 5g, Chinese blister beetle 0.18g, rheum officinale 30g, calomel mercurous chloride 3g, Alum 6g, Fructus meliae toosendan 18g, Chinese prickly ash 8g, kuh-seng 16g, moutan bark 16g, folium artemisiae argyi 12g, frutus cnidii 16g, root bark of shaggy-fruited dittany 26g, erythrina bark 16g。

Model case

Through clinical conditions psoriatic totally 605, the age is 305 of more than 20 years old, only 300 be 20 years old with Under.580 fully recovered in 605 patients, effective 23, total effective rate is up to 100%.

Claims (3)

1. one kind treats psoriasic external used medicine, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

12~20g of rumex root, 12~20g of Golden Larch Bark, 0.3~1g of chaulmoogra benevolence, 10~45g of radix rehmanniae recen, 2~5g of centipede, Chinese blister beetle 0.06~0.18g, 3~30g of rheum officinale, 1~3g of calomel mercurous chloride, 1~6g of alum, 8~18g of Fructus meliae toosendan, 3~8g of Chinese prickly ash, 8~16g of kuh-seng, 8~16g of moutan bark, 3~12g of folium artemisiae argyi, 5~16g of frutus cnidii, 10~26g of the root bark of shaggy-fruited dittany, 6~16g of erythrina bark.

2. the psoriasic external used medicine for the treatment of according to claim 1, it is characterised in that each component of the medicine and Its mass parts is than as follows：

13~17g of rumex root, 13~17g of Golden Larch Bark, 0.4~0.8g of chaulmoogra benevolence, 12~40g of radix rehmanniae recen, 3~4.5g of centipede, 0.08~0.16g of Chinese blister beetle, 5~26g of rheum officinale, 1.5~2.5g of calomel mercurous chloride, 2~5.5g of alum, 10~16g of Fructus meliae toosendan, 5~7g of Chinese prickly ash, 10~14g of kuh-seng, 10~14g of moutan bark, 5~11g of folium artemisiae argyi, 8~14g of frutus cnidii, 11~23g of the root bark of shaggy-fruited dittany, 8~14g of erythrina bark.

3. the psoriasic external used medicine for the treatment of according to claim 1 to 2, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

Rumex root 15g, Golden Larch Bark 15g, chaulmoogra benevolence 0.6g, radix rehmanniae recen 35g, centipede 4g, Chinese blister beetle 0.15g, rheum officinale 23g, calomel mercurous chloride 2.3g, alum 5g, Fructus meliae toosendan 14g, Chinese prickly ash 6g, kuh-seng 12g, moutan bark 12g, folium artemisiae argyi 10g, frutus cnidii 12g, root bark of shaggy-fruited dittany 20g, sea Paulownia skin 12g.