CN102869353A - 自身免疫疾病的治疗 - Google Patents

自身免疫疾病的治疗 Download PDF

Info

Publication number
CN102869353A
CN102869353A CN2011800224469A CN201180022446A CN102869353A CN 102869353 A CN102869353 A CN 102869353A CN 2011800224469 A CN2011800224469 A CN 2011800224469A CN 201180022446 A CN201180022446 A CN 201180022446A CN 102869353 A CN102869353 A CN 102869353A
Authority
CN
China
Prior art keywords
alkyl
alkoxy
formula
halogen
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800224469A
Other languages
English (en)
Chinese (zh)
Inventor
P·盖尔格利
E·沃尔斯特罗姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42199281&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102869353(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN102869353A publication Critical patent/CN102869353A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/24Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C07C321/28Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C07C321/30Sulfides having the sulfur atom of at least one thio group bound to two carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN2011800224469A 2010-05-06 2011-05-05 自身免疫疾病的治疗 Pending CN102869353A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10162079 2010-05-06
EP10162079.7 2010-05-06
PCT/EP2011/057203 WO2011138393A1 (en) 2010-05-06 2011-05-05 Treatment of autoimmune diseases

Publications (1)

Publication Number Publication Date
CN102869353A true CN102869353A (zh) 2013-01-09

Family

ID=42199281

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800224469A Pending CN102869353A (zh) 2010-05-06 2011-05-05 自身免疫疾病的治疗

Country Status (24)

Country Link
US (1) US20130172297A1 (enExample)
EP (1) EP2566470A1 (enExample)
JP (1) JP2013530937A (enExample)
KR (1) KR20130066630A (enExample)
CN (1) CN102869353A (enExample)
AU (1) AU2011249784B2 (enExample)
BR (1) BR112012028190A2 (enExample)
CA (1) CA2795394A1 (enExample)
CL (1) CL2012003091A1 (enExample)
CR (1) CR20120566A (enExample)
CU (1) CU20120154A7 (enExample)
EA (1) EA201201514A1 (enExample)
EC (1) ECSP12012312A (enExample)
IL (1) IL222690A0 (enExample)
MA (1) MA34285B1 (enExample)
MX (1) MX2012012926A (enExample)
NZ (1) NZ603999A (enExample)
PE (1) PE20130612A1 (enExample)
PH (1) PH12012502418A1 (enExample)
SG (1) SG185746A1 (enExample)
TN (1) TN2012000509A1 (enExample)
TW (1) TW201201814A (enExample)
WO (1) WO2011138393A1 (enExample)
ZA (1) ZA201207710B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI519539B (zh) 2010-12-21 2016-02-01 Kyorin Seiyaku Kk Diphenyl sulfide derivatives and pharmaceuticals as an active ingredient thereof
US9289494B2 (en) 2013-11-20 2016-03-22 RestorTears, LLC Method of treating ocular disorders with compounds found in Harderian gland secretions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003029184A1 (en) 2001-09-27 2003-04-10 Kyorin Pharmaceutical Co., Ltd. Diaryl ether derivative, addition salt thereof, and immunosuppressant
AU2002332289B2 (en) * 2001-09-27 2007-05-10 Kyorin Pharmaceutical Co., Ltd. Diaryl sulfide derivative, addition salt thereof, and immunosuppressant
US7482491B2 (en) 2002-09-19 2009-01-27 Kyorin Pharmaceutical Co., Ltd. Amino alcohol derivative, addition salt thereof, and immunosuppressant
WO2004074297A1 (ja) * 2003-02-18 2004-09-02 Kyorin Pharmaceutical Co., Ltd. アミノホスホン酸誘導体とその付加塩及びs1p受容体調節剤
ES2351393T3 (es) * 2003-05-26 2011-02-03 Takeda Pharmaceutical Company Limited Sulfopirroles.
MXPA06002349A (es) 2003-08-28 2006-05-22 Novartis Ag Derivados de aminopropanol.
CN1918148B (zh) * 2004-02-11 2012-09-05 巴斯利尔药物股份公司 取代的苯并咪唑和它们诱导细胞凋亡的用途
JPWO2006041015A1 (ja) * 2004-10-12 2008-05-15 杏林製薬株式会社 アミノアルコール誘導体とその付加塩及び免疫抑制剤
GB0504544D0 (en) * 2005-03-04 2005-04-13 Novartis Ag Organic compounds
CA2820510A1 (en) * 2005-09-09 2007-03-15 Novartis Ag Treatment of autoimmune diseases

Also Published As

Publication number Publication date
EA201201514A1 (ru) 2013-05-30
ECSP12012312A (es) 2012-12-28
AU2011249784A1 (en) 2012-12-20
TN2012000509A1 (en) 2014-04-01
CA2795394A1 (en) 2011-11-10
KR20130066630A (ko) 2013-06-20
TW201201814A (en) 2012-01-16
AU2011249784B2 (en) 2014-03-06
WO2011138393A1 (en) 2011-11-10
PH12012502418A1 (en) 2018-03-21
SG185746A1 (en) 2013-01-30
ZA201207710B (en) 2013-06-26
NZ603999A (en) 2014-06-27
PE20130612A1 (es) 2013-06-06
CU20120154A7 (es) 2013-03-27
MA34285B1 (fr) 2013-06-01
IL222690A0 (en) 2012-12-31
US20130172297A1 (en) 2013-07-04
CR20120566A (es) 2013-01-09
CL2012003091A1 (es) 2013-03-22
BR112012028190A2 (pt) 2016-08-02
MX2012012926A (es) 2012-12-17
JP2013530937A (ja) 2013-08-01
EP2566470A1 (en) 2013-03-13

Similar Documents

Publication Publication Date Title
KR101698028B1 (ko) 수용성 아세트아미노펜 유사체
CN110305095A (zh) 色甘酸衍生物以及成像和治疗的相关方法
CN103619330A (zh) 用于治疗糖尿病的选择性雄激素受体调节剂
CN107001806B (zh) 用于治疗心肺疾病的鞘氨醇-1-磷酸盐受体调节剂
JP2017019854A (ja) 自己免疫性疾患の処置剤
CN105985295B (zh) 一种旋光纯的硫代乙酸类化合物
WO2022140397A1 (en) Methods of treating cancer
CN102869353A (zh) 自身免疫疾病的治疗
CN112118843B (zh) 使用吲哚化合物治疗疼痛或间质性膀胱炎的方法
EP4349341A1 (en) Pharmaceutical preparation for preventing or treating pulmonary fibrosis
JP6290963B2 (ja) ジアリールスルフィド誘導体の投与レジメン
WO2018013625A1 (en) Deuterated miconazole
US20080207667A1 (en) Use of nalbuphine and related compounds to treat symptoms of respiratory problems
JP4829478B2 (ja) 医薬組成物
BR112021013637A2 (pt) Inibidores da síntese de leucotrieno
US20250002512A1 (en) Novel anti-depressant and neuroplastic agents and therapeutic uses thereof
JP5765650B2 (ja) インフルエンザウイルス感染症の予防および/または治療剤
TW201806601A (zh) σ受體配體在皰疹後遺疼痛中的用途
CN114874202A (zh) 一种用于治疗阿尔茨海默症的药物及其用途
JP2024536229A (ja) Irhom2阻害剤及びその使用
JP2004331661A (ja) 医薬組成物
HK40049577A (en) Indole compound for treating interstitial cystitis
HK40049577B (en) Indole compound for treating interstitial cystitis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Address after: Basel

Applicant after: Novartis Ag

Address before: Basel

Applicant before: Novartis AG

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: NOVARTIS AG TO: NOVARTIS CO., LTD.

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20130109