CN102861309A - Preparation method of composition consisting of herba agrimoniae and rhizoma zingiberis - Google Patents
Preparation method of composition consisting of herba agrimoniae and rhizoma zingiberis Download PDFInfo
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- CN102861309A CN102861309A CN201210352400XA CN201210352400A CN102861309A CN 102861309 A CN102861309 A CN 102861309A CN 201210352400X A CN201210352400X A CN 201210352400XA CN 201210352400 A CN201210352400 A CN 201210352400A CN 102861309 A CN102861309 A CN 102861309A
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- herba agrimoniae
- rhizoma zingiberis
- zingiberis recens
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of a preparation technology of a natural health-care food and a traditional Chinese medicine, in particular to a preparation method of a composition consisting of herba agrimoniae and rhizoma zingiberis. A herba agrimoniae dry extract, a herba agrimoniae and rhizoma zingiberis dry extract or a herba agrimoniae and rhizoma zingiberis water extraction dry extract or a rhizoma zingiberis water extraction dry extract and the like are obtained by decompression, vacuum drying or spray drying through the extraction methods of adding water for extraction or adding water for extraction, alcohol precipitation or ethanol heating and refluxing extraction, or ethanol soaking, and the like. The extracts are prepared into granules by adding 90% ethanol or 90% ethanol for conventional sugar-free adjuvants to pelletize, granulating and drying; or the soft capsules are obtained by grinding or screening the extracts to obtain dry paste powder, and adding soybean oil, beewax and soyabean lecithin according to a preparation technology of a soft capsule; or the extracts are ground and screened to obtain the dry paste powder, the conventional sugar-free adjuvants are added to be prepared into capsules or pressed to tablets. The product has the effects of reducing blood sugar and urine sugar, and is free from toxic and side effects.
Description
Technical field
The present invention relates to natural health care and preparation technique of traditional Chinese medicine technical field, be specifically related to a kind of preparation method of the compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens.
Background technology
The report that many Herba Agrimoniaes are used for diabetes had appearred in recent years clinically, the fundamental Chinese medicine of Herba Agrimoniae treatment diabetes is: but the Herba Agrimoniae tonify deficiency, be widely used in the treatment impairment caused by overstrain and take off power, therefore, the Herba silenes fortunei of more generally being called among the people, the Herba silenes fortunei of Shanghai and Zhejiang pharmacy prescription usefulness is this product now.Impairment caused by overstrain is taken off power and is claimed again general edema with yellowish tinge of the skin, and " Chinese medicine voluminous dictionary " carries: " general edema with yellowish tinge of the skin, due to this card is injured by forced labour, sick like malnutrition with jaundice due to indigestion and overstrain. and it is easily hungry to have a liking for food, and idle feelings are unable, and coolie people suffers from it more." main suit's symptom of diabetics, also be bulimia, idle unable, therefore can treat diabetes.
Clinical Chinese medical discrimination thinks, the pathogenesis of diabetes mainly with the deficiency of YIN scorching be crucial, and Herba Agrimoniae character is mild, can the tonify deficiency righting, again can clearing away deficiency-heat, therefore can treat " quenching one's thirst ".The deficiency of YIN must be answered, scorching clearly, the spontaneous recovery of quenching one's thirst.
Also confirmation of modern pharmacology research, Herba Agrimoniae can promote the hypoglycemic activity of insulin release and similar insulin really.Tian Limei etc. adopt alloxan to induce experimental rabbit hyperglycemia level take rabbit as experimental subject, continuous irrigation stomach Herba Agrimoniae decoct 10 days, and rabbit blood glucose significantly reduces.Fan Shangtan etc. confirm that further Herba Agrimoniae can significantly reduce normal white mice blood glucose.Herba Agrimoniae is similar to insulin to glycometabolic effect, can promote the picked-up of the peripheral tissues such as muscle and utilize glucose, the enzymatic synthesis of inducing hepatocyte glucokinase, impel glyconeogenesis and the saccharide oxidation of muscle and liver, ATP/ADP ratio is raise, thereby the body vigor is increased, receive the effect of strong body; But the white mice blood sugar increasing that the Herba Agrimoniae inhibited adrenaline is induced illustrates that Herba Agrimoniae has pair antiadrenergic drug to decompose the effect of liver glycogen; Herba Agrimoniae has obvious hypoglycemic activity to the alloxan diabetes white mice, and the prompting Herba Agrimoniae has certain protective role to beta Cell of islet, promotes the beta Cell of islet excreting insulin, improves defect of insulin secretion.The employing Streptozocins (STZ) such as Wang Sigong and epinephrine (Adr) copy the diabetes mice model, with Herba Agrimoniae granule gavage, observe its hypoglycemic activity, find that this medicine can resist the blood sugar increasing that STZ and Adr cause, improve carbohydrate tolerance, increase liver glycogen synthetic, mechanism of action may be relevant to sugared trans-utilization with its promotion insulin secretion or increase tissue.
Rhizoma Zingiberis Recens in the compositions mainly is to play after the patient takes this product, utilizes the effect of its relieving the exterior syndrome by diaphoresis, makes blood sugar reducing component in the Herba Agrimoniae extract can bring into play more rapidly the effect of its blood sugar lowering and urine glucose lowering.
Herba Agrimoniae extract has certain bitter taste, and the volatile oil of Rhizoma Zingiberis Recens can strengthen the secretion of gastric juice and the wriggling of intestinal wall, thereby helps digest; The zingiberene of separating in the Rhizoma Zingiberis Recens, the mixture of zingiberone have obvious preventing or arresting vomiting to tell effect, utilize its warming middle-JIAO to arrest vomiting, the effect of warming the lung to relieve cough, alleviation user's vomiting reaction.
The present invention has selected namely can the Chinese medicine Herba Agrimoniae of very good effect be arranged again to blood sugar lowering as the food long-term taking, is equipped with Rhizoma Zingiberis Recens, and by rational prescription, the processes of science has been made health food and Chinese medicine with auxiliary hyperglycemic.
The present invention provides a kind of preparation method of the compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens, is used for adjuvant therapy of diabetes.This product has blood sugar lowering, promotes blood circulation in reduction glucose in urine, optical fundus, and vision is recovered lost eyesight, rehabilitation flesh skin, Yin Yang balancing, the effect of balance internal organs, and nontoxic, side effect.
Summary of the invention
The present invention provides a kind of preparation method of the compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens, is used for adjuvant therapy of diabetes.This product has blood sugar lowering, promotes blood circulation in reduction glucose in urine, optical fundus, and vision is recovered lost eyesight, rehabilitation flesh skin, Yin Yang balancing, the effect of balance internal organs.
Technical scheme provided by the invention is: a kind of preparation method of the compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens, and it is the compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens, and said composition is made with the following method, and its step is as follows:
With after the garbled Herba Agrimoniae drying or with after the garbled Herba Agrimoniae drying and Rhizoma Zingiberis Recens, being crushed to particle diameter is 2～4cm.Add 10～6 times of amounts of water at every turn, extract 2 times, each 0.2～3 hour, filtered while hot, merging filtrate is concentrated, and the relative density that is evaporated to extractum is 1.20～1.50.Adding 95% amount of alcohol is 2～6 times of amounts of concentrated solution, and alcohol was analysed 8～48 hours, filters, and the relative density that is evaporated to extractum is 1.20～1.50, and vacuum drying or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 2～10 times of amounts that 20%～95% amount of alcohol is raw material at every turn, heating and refluxing extraction 0.2～5 hour, filter, getting the relative density that supernatant is evaporated to extractum is 1.20～1.50, and vacuum drying or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 2～10 times of amounts that 20%～95% amount of alcohol is raw material at every turn, and flooded 0.1～20 hour, volatilize extracting solution, vacuum drying or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
With after the garbled Herba Agrimoniae drying and Rhizoma Zingiberis Recens, being crushed to particle diameter is 2～4cm, add 6～10 times of amounts of water at every turn, extract 2 times, each 0.2～5 hour, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.20～1.50, and vacuum drying or spray drying namely get the Herba Agrimoniae gingerade and promote extractum.
With garbled Rhizoma Zingiberis Recens, being crushed to particle diameter is 2～4cm, adds 6～10 times of amounts of water at every turn, extract 2 times, each 0.2～5 hour, filtered while hot, merging filtrate, the relative density that is evaporated to extractum is 1.20～1.50, vacuum drying or spray drying namely get gingerade and promote extractum.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promotion extractum 90% alcohol granulation, granulate, drying, packing, granulation agent.Or add conventional sugar-free adjuvant 90% alcohol granulation, granulate, drying, packing, granulation agent.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract powder; With soybean oil, Cera Flava and soybean phospholipid, stir, grind, suppress soft capsule by the preparation technology of soft capsule, through typing, wash ball, the operation such as dry is made soft capsule.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract powder; Adding conventional sugar-free adjuvant makes capsule or is pressed into tablet.
Technical problem to be solved by this invention can also further realize by following technical scheme
Be characterized in, wherein the weight proportion of plant material is:
Raw material: Herba Agrimoniae 1～10000g, Rhizoma Zingiberis Recens 1～10000g
Wherein the weight proportion of preferred plant material is:
Raw material: 1, Herba Agrimoniae 5750g, Rhizoma Zingiberis Recens 1500g
2, Herba Agrimoniae 1150g Rhizoma Zingiberis Recens 300g
Below be the preferred technical scheme of the present invention: with 5750g after the garbled Herba Agrimoniae drying or with 5750g and Rhizoma Zingiberis Recens 1500g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is 2～4cm.Add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, and the relative density that is evaporated to extractum is 1.20～1.25.Adding 95% amount of alcohol is 2 times of amounts of concentrated solution, alcohol was analysed 8 hours, filter, getting the relative density that supernatant is evaporated to extractum is 1.45～1..47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 6 times of amounts that 60% amount of alcohol is raw material at every turn, heating and refluxing extraction 2 hours, filter, getting the relative density that supernatant is evaporated to extractum is 1.45～1..47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 8 times of amounts that 70% amount of alcohol is raw material at every turn, and flooded 3 hours, volatilize extracting solution, 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
With 5750g Rhizoma Zingiberis Recens 1500g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1..47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get the Herba Agrimoniae gingerade and promote extractum.
With garbled Rhizoma Zingiberis Recens 1500g, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1..47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get gingerade and promote extractum.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promotion extractum, use 90% alcohol granulation, granulate, drying, packing, granulation agent.Or add conventional sugar-free adjuvant 90% alcohol granulation, granulate, drying, packing, granulation agent.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract approximately 1000g of powder; Add dried cream powder approximately 1000g, soybean oil 1125g, Cera Flava 75g, soybean phospholipid 50g stir, grind, suppress soft capsule by the preparation technology of soft capsule, through typing, wash ball, the operation such as dry is made soft capsule.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract approximately 1000g of powder; Approximately 1000g and sugar-free adjuvant commonly used are made capsule or are pressed into tablet to add dried cream powder.
Technical problem to be solved by this invention also can be come further realization by the following technical programs, is characterized in, wherein the weight proportion of plant material is:
Raw material: Herba Agrimoniae 1～10000g, Rhizoma Zingiberis Recens 1～10000g
Wherein the weight proportion of preferred feedstock is:
Raw material: 1, Herba Agrimoniae 5750g, Rhizoma Zingiberis Recens 1500g
2, Herba Agrimoniae 1150g Rhizoma Zingiberis Recens 300g
The specific embodiment:
The present invention will be further described below by specific embodiment, and each embodiment only is used for explanation the present invention, does not limit the present invention:
Example 1
" Herba Agrimoniae hypoglycemic granule " prescription:
Raw material: Herba Agrimoniae 5750g, Rhizoma Zingiberis Recens 1500g
The sugar-free right amount of auxiliary materials
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Make 1000g
With 5750g after the garbled Herba Agrimoniae drying or with 5750g and Rhizoma Zingiberis Recens 1500g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is 2～4cm.Add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, and the relative density that is evaporated to extractum is 1.20～1.25.Adding 95% amount of alcohol is 2 times of amounts of concentrated solution, and alcohol was analysed 8 hours, filters, and getting the relative density that supernatant is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 6 times of amounts that 60% amount of alcohol is raw material at every turn, heating and refluxing extraction 2 hours, filter, getting the relative density that supernatant is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 8 times of amounts that 70% amount of alcohol is raw material at every turn, and flooded 3 hours, volatilize extracting solution, 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
With 5750g and Rhizoma Zingiberis Recens 1500g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get the Herba Agrimoniae gingerade and promote extractum.
With garbled Rhizoma Zingiberis Recens 1500g, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get gingerade and promote extractum.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promotion extractum, use 90% alcohol granulation, granulate, drying, packing, granulation agent.Or add microcrystalline Cellulose 4-8% 90% alcohol granulation, granulate, drying, packing, granulation agent.
Example 2
" Herba Agrimoniae blood-sugar lowering soft capsule " prescription:
Raw material: Herba Agrimoniae 1150g Rhizoma Zingiberis Recens 300g
Vegetable oil, gelatin, glycerol are an amount of
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Make 1000
With 1150g after the garbled Herba Agrimoniae drying or with 1150g and Rhizoma Zingiberis Recens 300g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is that 2～4cm. adds water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, and the relative density that is evaporated to extractum is 1.20～1.25.Adding 95% amount of alcohol is 2 times of amounts of concentrated solution, and alcohol was analysed 8 hours, filters, and getting the relative density that supernatant is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 6 times of amounts that 60% amount of alcohol is raw material at every turn, heating and refluxing extraction 2 hours, filter, getting the relative density that supernatant is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 8 times of amounts that 70% amount of alcohol is raw material at every turn, and flooded 3 hours, volatilize extracting solution, 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
With 1150g and Rhizoma Zingiberis Recens 300g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get the Herba Agrimoniae gingerade and promote extractum.
With garbled Rhizoma Zingiberis Recens 300g, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get gingerade and promote extractum.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract approximately 200g of powder; Add dried cream powder approximately 200g, soybean oil 225g, Cera Flava 15g, soybean phospholipid 10g stir, grind, suppress soft capsule by the preparation technology of soft capsule, through typing, wash ball, the operation such as dry is made soft capsule.
Example 3
" Herba Agrimoniae Jiangtang capsule " prescription
Raw material: Herba Agrimoniae 1150g Rhizoma Zingiberis Recens 300g
The sugar-free right amount of auxiliary materials
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Make 1000
With 1150g after the garbled Herba Agrimoniae drying or with 1150g and Rhizoma Zingiberis Recens 300g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is that 2～4cm. adds water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, and the relative density that is evaporated to extractum is 1.20～1.25.Adding 95% amount of alcohol is 2 times of amounts of concentrated solution, and alcohol was analysed 8 hours, filters, and getting the relative density that supernatant is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 6 times of amounts that 60% amount of alcohol is raw material at every turn, heating and refluxing extraction 2 hours, filter, getting the relative density that supernatant is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.Or add 8 times of amounts that 70% amount of alcohol is raw material at every turn, and flooded 3 hours, volatilize extracting solution, 80 ℃ of vacuum dryings or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
With 1150g and Rhizoma Zingiberis Recens 300g after the garbled Herba Agrimoniae drying, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get the Herba Agrimoniae gingerade and promote extractum.
With garbled Rhizoma Zingiberis Recens 300g, being crushed to particle diameter is 2～4cm, add water 10,6 times of amounts at every turn, extract 2 times, each 1.5,1.5 hours, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.45～1.47 or 1.20～1.25, and 80 ℃ of vacuum dryings or spray drying namely get gingerade and promote extractum.
Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract approximately 200g of powder; Approximately 200g and sugar-free adjuvant commonly used are made capsule or are pressed into tablet to add dried cream powder.
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Claims (12)
1. the preparation method of a compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens, it is characterized in that take Herba Agrimoniae, Rhizoma Zingiberis Recens as raw material, its step is as follows:
(1) with after the garbled Herba Agrimoniae drying or with after the garbled Herba Agrimoniae drying and Rhizoma Zingiberis Recens, being crushed to particle diameter is 2～4cm.
2. add 10～6 times of amounts of water at every turn, extract 2 times, each 0.2～3 hour, filtered while hot, merging filtrate is concentrated, and the relative density that is evaporated to extractum is 1.20～1.50.
3. adding 95% amount of alcohol is 2～6 times of amounts of concentrated solution, and alcohol was analysed 8～48 hours, filters, and the relative density that is evaporated to extractum is 1.20～1.50, and vacuum drying or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
4. or at every turn adding 20%～95% amount of alcohol is 2～10 times of amounts of raw material, heating and refluxing extraction 0.2～5 hour, filter, getting the relative density that supernatant is evaporated to extractum is 1.20～1.50, and vacuum drying or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
5. or at every turn adding 20%～95% amount of alcohol is 2～10 times of amounts of raw material, floods 0.1～20 hour, volatilizes extracting solution, and vacuum drying or spray drying namely get Herba Agrimoniae dry extract and Herba Agrimoniae Rhizoma Zingiberis Recens dry extract.
6.(2) with garbled Herba Agrimoniae and Rhizoma Zingiberis Recens, being crushed to particle diameter is 2～4cm, add 6～10 times of amounts of water at every turn, extract 2 times, each 0.2～5 hour, filtered while hot, merging filtrate is concentrated, the relative density that is evaporated to extractum is 1.20～1.50, and vacuum drying or spray drying namely get the Herba Agrimoniae gingerade and promote extractum.
7.(3) with garbled Rhizoma Zingiberis Recens, being crushed to particle diameter is 2～4cm, adds 6～10 times of amounts of water at every turn, extract 2 times, each 0.2～5 hour, filtered while hot, merging filtrate, the relative density that is evaporated to extractum is 1.20～1.50, vacuum drying or spray drying namely get gingerade and promote extractum.
8.(4) Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promotion extractum 90% alcohol granulation, granulate, drying, packing, granulation agent.
9. or add conventional sugar-free adjuvant 90% alcohol granulation, granulate, drying, packing, granulation agent.
10.(5) Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract powder; With soybean oil, Cera Flava and soybean phospholipid, stir, grind, suppress soft capsule by the preparation technology of soft capsule, through typing, wash ball, the operation such as dry is made soft capsule.
11.(6) Herba Agrimoniae dry extract and gingerade are promoted extractum or Herba Agrimoniae Rhizoma Zingiberis Recens dry extract or Herba Agrimoniae gingerade promote extractum, pulverize, sieve, mix homogeneously gets dry extract powder; Adding conventional sugar-free adjuvant makes capsule or is pressed into tablet.
12. the preparation method of a kind of compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens according to claim 1, it is characterized in that take Herba Agrimoniae, Rhizoma Zingiberis Recens as raw material, and wherein the weight proportion of plant material is:
Raw material: Herba Agrimoniae 1～10000g, Rhizoma Zingiberis Recens 1～10000g
The preparation method of a kind of compositions that is formed by Herba Agrimoniae, Rhizoma Zingiberis Recens according to claim 1, it is characterized in that take Herba Agrimoniae, Rhizoma Zingiberis Recens as raw material, wherein the weight proportion of plant material is:
Raw material: 1, Herba Agrimoniae 5750g, Rhizoma Zingiberis Recens 1500g
2, Herba Agrimoniae 1150g, Rhizoma Zingiberis Recens 300g.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106261446A (en) * | 2016-08-19 | 2017-01-04 | 上海世道健康科技有限公司 | A kind of medicinal and edible plant Granular formulations with damp eliminating effect and preparation method |
| CN106581626A (en) * | 2017-02-07 | 2017-04-26 | 王传金 | Medicine formula capable of reducing blood sugar of diabetic patients and preparation method of medicine formula |
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2012
- 2012-09-21 CN CN201210352400XA patent/CN102861309A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106261446A (en) * | 2016-08-19 | 2017-01-04 | 上海世道健康科技有限公司 | A kind of medicinal and edible plant Granular formulations with damp eliminating effect and preparation method |
| CN106581626A (en) * | 2017-02-07 | 2017-04-26 | 王传金 | Medicine formula capable of reducing blood sugar of diabetic patients and preparation method of medicine formula |
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Application publication date: 20130109 |