CN102858347B - 用作胆汁酸螯合剂的聚咪唑 - Google Patents

用作胆汁酸螯合剂的聚咪唑 Download PDF

Info

Publication number
CN102858347B
CN102858347B CN201180020473.2A CN201180020473A CN102858347B CN 102858347 B CN102858347 B CN 102858347B CN 201180020473 A CN201180020473 A CN 201180020473A CN 102858347 B CN102858347 B CN 102858347B
Authority
CN
China
Prior art keywords
polymer
amine
purposes
medicine
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180020473.2A
Other languages
English (en)
Chinese (zh)
Other versions
CN102858347A (zh
Inventor
I·利斯
K·比亚尼
E·康纳
S·赫克
张洪敏
M·J·科普
E·戈卡
A·李
D·马德森
绍钧
张新南
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Relypsa Inc
Original Assignee
Relypsa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Relypsa Inc filed Critical Relypsa Inc
Priority to CN201610881008.2A priority Critical patent/CN106478948B/zh
Publication of CN102858347A publication Critical patent/CN102858347A/zh
Application granted granted Critical
Publication of CN102858347B publication Critical patent/CN102858347B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0273—Polyamines containing heterocyclic moieties in the main chain
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0605—Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0616—Polycondensates containing five-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only two nitrogen atoms in the ring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0622—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0627—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only one nitrogen atom in the ring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/18—Polybenzimidazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Resins (AREA)
CN201180020473.2A 2010-02-24 2011-02-24 用作胆汁酸螯合剂的聚咪唑 Expired - Fee Related CN102858347B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610881008.2A CN106478948B (zh) 2010-02-24 2011-02-24 用作胆汁酸螯合剂的聚咪唑

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30781910P 2010-02-24 2010-02-24
US30781610P 2010-02-24 2010-02-24
US61/307,819 2010-02-24
US61/307,816 2010-02-24
PCT/US2011/026102 WO2011106545A1 (en) 2010-02-24 2011-02-24 Polyimidazoles for use as bile acid sequestrants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201610881008.2A Division CN106478948B (zh) 2010-02-24 2011-02-24 用作胆汁酸螯合剂的聚咪唑

Publications (2)

Publication Number Publication Date
CN102858347A CN102858347A (zh) 2013-01-02
CN102858347B true CN102858347B (zh) 2016-11-02

Family

ID=43975199

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201180020473.2A Expired - Fee Related CN102858347B (zh) 2010-02-24 2011-02-24 用作胆汁酸螯合剂的聚咪唑
CN201610881008.2A Expired - Fee Related CN106478948B (zh) 2010-02-24 2011-02-24 用作胆汁酸螯合剂的聚咪唑

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201610881008.2A Expired - Fee Related CN106478948B (zh) 2010-02-24 2011-02-24 用作胆汁酸螯合剂的聚咪唑

Country Status (10)

Country Link
US (2) US20130189215A1 (cg-RX-API-DMAC10.html)
EP (2) EP3130343B1 (cg-RX-API-DMAC10.html)
JP (3) JP5964247B2 (cg-RX-API-DMAC10.html)
CN (2) CN102858347B (cg-RX-API-DMAC10.html)
AU (2) AU2011220745B2 (cg-RX-API-DMAC10.html)
BR (1) BR112012021448A2 (cg-RX-API-DMAC10.html)
CA (1) CA2790899C (cg-RX-API-DMAC10.html)
ES (1) ES2598500T3 (cg-RX-API-DMAC10.html)
GB (1) GB2490853B (cg-RX-API-DMAC10.html)
WO (1) WO2011106545A1 (cg-RX-API-DMAC10.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017106587A (ru) 2010-02-24 2019-01-21 Релипса, Инк. Аминосодержащие полимеры для применения в качестве секвестрантов желчных кислот
ES2549513T3 (es) 2010-02-24 2015-10-28 Relypsa, Inc. Polivinilamina, polialilamina y polietilenimina reticuladas para uso como secuestradores de ácidos biliares
US20130244234A1 (en) * 2012-01-23 2013-09-19 Glc Biotechnology, Inc. Stool collection methods for analysis of dna in stool
JP6227535B2 (ja) * 2012-08-30 2017-11-08 株式会社三和化学研究所 脂質異常症の予防又は治療薬
KR102633597B1 (ko) 2013-06-05 2024-02-06 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
WO2015161117A2 (en) 2014-04-16 2015-10-22 The Uab Research Foundation Msp nanopores and uses thereof
ES2908142T3 (es) 2014-06-13 2022-04-27 United Therapeutics Corp Formulaciones de treprostinil
IL322207A (en) 2014-12-10 2025-09-01 Tricida Inc Proton-binding polymers for oral administration
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
US11090354B2 (en) * 2015-08-06 2021-08-17 The Johns Hopkins University Composition and method for treatment of metabolic disorders
CN106967217A (zh) * 2016-01-14 2017-07-21 华南理工大学 聚咪唑类化合物及其原位制备方法和应用
IL262660B2 (en) 2016-05-06 2024-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
JP6792640B2 (ja) 2016-12-28 2020-11-25 富士フイルム株式会社 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法
EP3698799B1 (en) 2017-10-16 2022-01-26 FUJIFILM Corporation Hyperphosphatemia treatment agent
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
CN109932349B (zh) * 2019-04-04 2021-04-20 济南大学 一种检测次氯酸的有机硅小分子荧光探针
CN114340632B (zh) * 2019-08-30 2024-09-17 赛特瑞恩股份有限公司 用于治疗或预防非酒精性脂肪性肝炎（nash）的药物组合物
JP2022548699A (ja) 2019-09-20 2022-11-21 グライセンド， インコーポレイテッド 置換フェニルボロン酸含有ポリマーおよび使用方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900233A (en) * 1997-10-16 1999-05-04 Day; Charles E. Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and its use in treating irritable bowel syndrome
US6111056A (en) * 1997-09-15 2000-08-29 Basf Aktiengesellschaft Cyclic amine based polymers and process for their production
US6147183A (en) * 1997-09-15 2000-11-14 Basf Aktiengesellschaft Amphoteric amine based polymers having a net cationic charge and process for their production

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60209523A (ja) * 1984-04-03 1985-10-22 Mitsubishi Petrochem Co Ltd コレステロ−ル低下剤
US4600578A (en) * 1984-05-11 1986-07-15 Bristol-Myers Company Method of inhibiting diarrhea
US4649048A (en) * 1984-05-11 1987-03-10 Bristol-Myers Company Novel bile sequestrant resin
ATE130193T1 (de) * 1992-03-28 1995-12-15 Hoechst Ag Arzneimittel aus polyhydroxymethylenderivaten, verfahren zu deren herstellung und verwendung.
JPH066667A (ja) 1992-06-22 1994-01-14 Canon Inc ぶれ検出装置及びぶれ補正装置
US5631365A (en) 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5414068A (en) 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
CN1189168A (zh) * 1995-06-06 1998-07-29 吉尔特药品公司 用于清除胆固醇的含疏水杂原子的螯合剂
JP4156684B2 (ja) * 1996-03-05 2008-09-24 三菱化学株式会社 高リン血症予防および／または治療剤
EP1121408B1 (en) * 1998-10-13 2005-02-23 The Procter & Gamble Company Laundry detergent compositions with a combination of cyclic amine based copolymers and hydrophobically modified cellulose
US6472364B1 (en) * 1998-10-13 2002-10-29 The Procter & Gamble Company Detergent compositions or components
AU1906500A (en) * 1999-10-29 2001-05-14 Procter & Gamble Company, The Laundry detergent compositions with fabric care
JP2002068985A (ja) * 2000-08-30 2002-03-08 Mitsubishi-Tokyo Pharmaceuticals Inc 薬剤性肝障害治療薬
EP1348442A4 (en) * 2000-11-28 2005-02-02 Mitsubishi Pharma Corp ANTI-OBESITY AGENTS AND DIET FOOD
US7879869B2 (en) * 2001-07-30 2011-02-01 Mitsubishi Tanabe Pharma Corporation Drugs for ameliorating postcibal hyperglycemia
JP2003113091A (ja) * 2001-10-02 2003-04-18 Sekisui Chem Co Ltd 胆汁酸特異的認識ポリマー及びコレステロール低下剤
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
BRPI0508966A (pt) * 2004-03-26 2007-08-21 Lilly Co Eli composto, composição farmacêutica, e, uso de um composto
JP4896480B2 (ja) * 2004-10-01 2012-03-14 第一三共ヘルスケア株式会社 陰イオン交換樹脂の粒子状組成物
JP6218355B2 (ja) * 2011-02-10 2017-10-25 ソニー株式会社 濾材
CN105900233A (zh) * 2013-12-13 2016-08-24 Wow研究中心有限公司 半导体装置及其制造方法
CN106147183A (zh) * 2015-04-01 2016-11-23 合肥杰事杰新材料股份有限公司 一种pc/abs合金材料及其制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6111056A (en) * 1997-09-15 2000-08-29 Basf Aktiengesellschaft Cyclic amine based polymers and process for their production
US6147183A (en) * 1997-09-15 2000-11-14 Basf Aktiengesellschaft Amphoteric amine based polymers having a net cationic charge and process for their production
US5900233A (en) * 1997-10-16 1999-05-04 Day; Charles E. Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and its use in treating irritable bowel syndrome

Also Published As

Publication number Publication date
EP2538947B1 (en) 2016-08-17
JP2013520562A (ja) 2013-06-06
CN106478948B (zh) 2019-05-07
WO2011106545A1 (en) 2011-09-01
JP6431499B2 (ja) 2018-11-28
GB201216799D0 (en) 2012-11-07
ES2598500T3 (es) 2017-01-27
JP2017101258A (ja) 2017-06-08
AU2017201276A1 (en) 2017-03-16
BR112012021448A2 (pt) 2016-05-31
CA2790899C (en) 2018-12-18
JP5964247B2 (ja) 2016-08-03
US20130189215A1 (en) 2013-07-25
CN102858347A (zh) 2013-01-02
AU2011220745B2 (en) 2016-12-01
JP2016169388A (ja) 2016-09-23
US20190169342A1 (en) 2019-06-06
EP3130343B1 (en) 2018-05-09
GB2490853B (en) 2018-08-08
GB2490853A (en) 2012-11-14
CA2790899A1 (en) 2011-09-01
AU2011220745A1 (en) 2012-09-13
EP3130343A1 (en) 2017-02-15
EP2538947A1 (en) 2013-01-02
CN106478948A (zh) 2017-03-08
AU2017201276B2 (en) 2018-09-27

Similar Documents

Publication Publication Date Title
AU2017201276B2 (en) Polyimidazoles for use as bile acid sequestrants
CN102906159B (zh) 用作胆汁酸螯合剂的胺聚合物
CN102858817B (zh) 用作胆汁酸螯合剂的交联聚乙烯胺、聚烯丙胺和乙烯亚胺

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20161102