CN102846740B - Navel-applied plaster for reducing high blood pressure caused by hyperactivity of liver-yang and preparation method thereof - Google Patents

Navel-applied plaster for reducing high blood pressure caused by hyperactivity of liver-yang and preparation method thereof Download PDF

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Publication number
CN102846740B
CN102846740B CN201210307568.9A CN201210307568A CN102846740B CN 102846740 B CN102846740 B CN 102846740B CN 201210307568 A CN201210307568 A CN 201210307568A CN 102846740 B CN102846740 B CN 102846740B
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parts
weight
radix
liver
vaseline
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CN102846740A (en
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孙霞
孙红
王茜
仪伟
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Qingdao Municipal Hospital
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Qingdao Municipal Hospital
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Abstract

A navel-applied plaster for reducing high blood pressure caused by hyperactivity of liver-yang provided by the invention comprises the following components, by weight: bulk medicines comprising 100-140 parts of chrysanthemum, 120-180 parts of Radix Paeoniae Alba, 80-120 parts of Ligusticum wallichii, 150-200 parts of Cortex Moutan Radicis, 80-120 parts of the root of straight ladybell and 80-120 parts of oriental wormwood; and auxiliary comprising 305-440 parts of vaseline and 305-440 parts of beeswax. The preparation method of the navel-applied plaster comprises the following steps: a. mixing chrysanthemum, Radix Paeoniae Alba, Ligusticum wallichii, Cortex Moutan Radicis, the root of straight ladybell and oriental wormwood according to the weight ratio, and crushing the mixture into a powder of higher than 100 mesh; and b. melting vaseline of the above weight parts at 38-60 DEG C, adding beeswax of the above weight parts, heating to 62-67 DEG C until complete melting, adding the medicinal powder according to the weight, rapid stirring, and cooling.

Description

Excessive rising of liver-YANG blood pressure lowering umbilica sticking plaster and preparation method thereof
Technical field
The invention belongs to Chinese medicine external umbilica sticking plaster field, be specially a kind of liver-heat rise the headache feeling of fullness in the head, the vertigo and tinnitus that cause, excessive rising of liver-YANG blood pressure lowering umbilica sticking plaster of the symptoms such as vascular hypertension and preparation method thereof of curing mainly.
Background technology
Hypertension belongs to the categories such as Chinese medicine " dizzy, headache ", and with cardiopalmus, palpitation with a distress feeling, apoplexy close association, patient's the five internal organs deficiency, decline of either YIN or YANG.Deficiency of both QI and blood is the intrinsic factor of morbidity, simultaneously, due to eating and drinking without temperance, the extrinsic factor such as excited, life style is bad, causes deficiency of the kidney, deficiency of kidney yin, the moon sun not processed.The kidney failing to nourish the liver, liver is lost bar and reaches, dysfunction of the spleen in transportation, according to statistics, in hypertension, syndrome of upper hyperactivity of liver yang ratio accounts for 87.33%.The hypertensive medicine of western medicine is numerous, and its curative effect also obtains certainly.But, the erious adverse reaction of western medicine, drug withdrawal is easily recurred, satisfied not to the utmost to the improvement of patients ' life quality.
Summary of the invention
The object of this invention is to provide a kind of determined curative effect, have no side effect, the simple excessive rising of liver-YANG blood pressure lowering of technique umbilica sticking plaster and preparation method thereof.
Excessive rising of liver-YANG blood pressure lowering umbilica sticking plaster of the present invention is by the crude drug of following parts by weight: 100~140 parts of Flos Chrysanthemis, 120~180 parts of the Radix Paeoniae Albas, 80~120 parts of Rhizoma Chuanxiongs, 150~200 parts of Cortex Moutans, 80~120 parts of Radix Adenophorae (Radix Glehniae), 80~120 parts of Herba Artemisiae Scopariaes; Be equipped with adjuvant: 305~440 parts, 305~440 parts, vaseline, Cera Flava are made.
The preparation method of this umbilica sticking plaster comprises the following steps: a, Flos Chrysanthemi, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Cortex Moutan, Radix Adenophorae (Radix Glehniae), Herba Artemisiae Scopariae are mixed according to described parts by weight, be ground into medicated powder more than 100 orders; B, the vaseline of described parts by weight is melted at 38 DEG C~60 DEG C, add the Cera Flava of described parts by weight, heat and completely after fusing, add the medicated powder of described parts by weight to 62 DEG C~67 DEG C, rapid stirring is even, cooling and get final product.。
Preferably, umbilica sticking plaster of the present invention can be by the crude drug of following parts by weight: 120 parts of Flos Chrysanthemis, 150 parts of the Radix Paeoniae Albas, 100 parts of Rhizoma Chuanxiongs, 180 parts of Cortex Moutans, 100 parts of Radix Adenophorae (Radix Glehniae), 100 parts of Herba Artemisiae Scopariaes; Be equipped with adjuvant: 375 parts, 375 parts, vaseline, Cera Flava are made.
Flos Chrysanthemi is refrigerant property wind-heat-dispersing medicinal, function dispelling wind heat, and clear the rank and file of outlaws, pathogenic fire reducing and removing toxic substances, cure mainly headache dizzy, and blood pressure is hyperfunction, nervous headache etc., also effect of favourable liver improving eyesight; The Radix Paeoniae Alba cures mainly pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, cold and heat, hernia abdominal mass, pain relieving, diuresis, QI invigorating; Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia; Cortex Moutan heat clearing away, removing heat from blood, and blood, repercussive, controls the pathogenic heat attacking blood system in febrile diseases, sends out speckle, and infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage; Radix Adenophorae (Radix Glehniae) nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, thirsty for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound; Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis, jaundice eliminating, for jaundice, dysuria, eczema pruritus, infectious jaundice type hepatitis.All medicine compatibilities, heat clearing away suppressing the hyperactive liver, treatment liver-heat rise the headache feeling of fullness in the head, the vertigo and tinnitus that cause, vascular hypertension texts is remarkable.
The present invention makes umbilica sticking plaster by said medicine and uses; compared with prior art there is following characteristics: Cera Flava has effect of astringent therapy, granulation promoting, pain relieving, removing toxic substances; vaseline has water proofing property, is a kind of extraordinary moisturizing articles for use, the raw material of using for preparing medical ointment and skin care ointment.The substrate (adjuvant) that it adopts as umbilica sticking plaster, chemical stabilization, and this umbilica sticking plaster has the feature of principal agent high volatility, preparation technology is easy, be conducive to umbilicus penetrates and absorbs, especially to skin of umbilicus place without anaphylaxis, more have no side effect.In addition the bad toxic and side effects that can avoid some oral drugs to bring generations such as patient's liver kidneys.
Relevant clinical data is as follows: in 120 routine cases, oldest 60 years old, minimum 32 years old, be divided at random three groups every group 40 examples.Three groups of cases are Epidemiological Analysis difference not statistically significant by statistics at aspects such as ages, has comparability.All cases, all with reference to Western medicine diagnose standard, are made a definite diagnosis according to " new Chinese medicine guideline of clinical investigations " criterion of therapeutical effect of the Diagnosing Hypertension of WHO revision in 1999 and grade scale and the dialectical standard of syndrome of upper hyperactivity of liver yang and Ministry of Public Health issue in 1993.
Diagnostic criteria: ideal bp: systolic pressure < 120mmHg, diastolic pressure < 80mmHg; Normal arterial pressure: systolic pressure < 130mmHg, diastolic pressure < 85mmHg; Normal high limit: systolic pressure 130~139mmHg, diastolic pressure 85~89mmHg; 1 grade of hypertension: systolic pressure 140~159mmHg, diastolic pressure 90~99mmHg (subgroup: borderline hypertension, systolic pressure 140~149mmHg, diastolic pressure 90~94mmHg); 2 grades of hypertension: systolic pressure 160~179mmHg, diastolic pressure 100~109mmHg.The dialectical standard of syndrome of upper hyperactivity of liver yang: 1. dizzy.2. headache.3. flush.4. irritated irritability.5. bitter taste and thirsty.6. stringy pulse.7. constipation.Possessing above-mentioned 4 persons can distinguish as liver-Yang sthenia type.
Therapeutic Method: three groups of each 45 examples, accept respectively embodiment 1, embodiment 2, embodiment 3 umbilicus patch clinical treatments, external (stance) is affixed on umbilical part and changes once for 48 hours, and manifold card is taken a day off for six days.It within 30 days, is a course for the treatment of.
Criterion of therapeutical effect: effective: diastolic pressure decline > 10mmHg is also down to normal or more than decline > 20mmHg, dizzy, headache symptom disappears substantially, and other symptoms obviously alleviate; Effective: though diastolic pressure declines and do not reach 10mmHg and be down to the normal or 10~19mmHg that declines, dizzy, headache symptom disappears substantially, but have dizziness, headache when excited, press ascensional range to be no more than 150/95mmHg; Invalid: not reach above-mentioned curative effect person.
After three groups of case treatments, curative effect comparative statistics result is as follows:
Group Embodiment 1 Embodiment 2 Embodiment 3
Number of cases 40 40 40
Effective (n%) 12(30%) 11(27.5%) 11(27.5%)
Effectively (n%) 23(57.5%) 23(57.5%) 22(55%)
Invalid (n%) 5(12.5%) 6(15%) 7(17.5%)
Anaphylaxis (n%) 0(0%) 0 (0%) 0 (0%)
Total effective rate (n%) 87.5% 85% 82.5%
Detailed description of the invention
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; according to the present invention, content, to nonessential improvement and adjustment more of the present invention, still belongs to protection scope of the present invention to those skilled in the art.
Embodiment 1: get 120 grams of Flos Chrysanthemis, 150 grams of the Radix Paeoniae Albas, 100 grams of Rhizoma Chuanxiongs, 180 grams of Cortex Moutans, 100 grams of Radix Adenophorae (Radix Glehniae), 100 grams of Herba Artemisiae Scopariaes, mix after drying at 35 DEG C, grinding and processing becomes medicated powder more than 100 orders.
First 375 grams of vaseline are melted at 50 DEG C, add 375 grams of Cera Flavas, heat to 63 DEG C completely fusing after, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted to ring size 2cm in 6cm × 7cm() the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, 1.5 grams of doses.8cm × 12cm compound membrane bag for the finished product processing is packed, and one pastes one bag.
Embodiment 2: get 100 grams of Flos Chrysanthemis, 120 grams of the Radix Paeoniae Albas, 80 grams of Rhizoma Chuanxiongs, 150 grams of Cortex Moutans, 80 grams of Radix Adenophorae (Radix Glehniae), 80 grams of Herba Artemisiae Scopariaes, mix after drying at 67 DEG C, grinding and processing becomes medicated powder more than 100 orders.
First 305 grams of vaseline are melted at 60 DEG C, add 305 grams of Cera Flavas, heat to 65 DEG C completely fusing after, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted to 7cm × 8cm(internal ring and is of a size of 2.5cm) the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose is 3 grams.8cm × 12cm compound membrane bag for the finished product processing is packed, and one pastes one bag.
Embodiment 3: get 140 grams of Flos Chrysanthemis, 180 grams of the Radix Paeoniae Albas, 120 grams of Rhizoma Chuanxiongs, 200 grams of Cortex Moutans, 120 grams of Radix Adenophorae (Radix Glehniae), 120 grams of Herba Artemisiae Scopariaes, mix after drying at 50 DEG C, grinding and processing becomes medicated powder more than 100 orders.
First 440 grams of vaseline are melted at 38 DEG C, add 440 grams of Cera Flavas, heat to 62 DEG C completely fusing after, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted to 7cm × 8cm(internal ring and is of a size of 2.5cm) the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose is 3.1 grams.8cm × 12cm compound membrane bag for the finished product processing is packed, and one pastes one bag.

Claims (3)

1. excessive rising of liver-YANG blood pressure lowering umbilica sticking plaster; It is characterized in that the crude drug by following parts by weight: 100~140 parts of Flos Chrysanthemis, 120~180 parts of the Radix Paeoniae Albas, 80~120 parts of Rhizoma Chuanxiongs, 150~200 parts of Cortex Moutans, 80~120 parts of Radix Adenophorae (Radix Glehniae), 80~120 parts of Herba Artemisiae Scopariaes; Be equipped with adjuvant: 305~440 parts, 305~440 parts, vaseline, Cera Flava are made.
2. umbilica sticking plaster according to claim 1, is characterized in that the crude drug by following parts by weight: 120 parts of Flos Chrysanthemis, 150 parts of the Radix Paeoniae Albas, 100 parts of Rhizoma Chuanxiongs, 180 parts of Cortex Moutans, 100 parts of Radix Adenophorae (Radix Glehniae), 100 parts of Herba Artemisiae Scopariaes; Be equipped with adjuvant: 375 parts, 375 parts, vaseline, Cera Flava are made.
3. a method of preparing umbilica sticking plaster described in claim 1, is characterized in that comprising the following steps:
A, Flos Chrysanthemi, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Cortex Moutan, Radix Adenophorae (Radix Glehniae), Herba Artemisiae Scopariae are mixed according to described parts by weight, be ground into medicated powder more than 100 orders;
B, the vaseline of described parts by weight is melted at 38 DEG C~60 DEG C, add the Cera Flava of described parts by weight, heat and completely after fusing, add the medicated powder of described parts by weight to 62 DEG C~67 DEG C, rapid stirring is even, cooling and get final product.
CN201210307568.9A 2012-08-28 2012-08-28 Navel-applied plaster for reducing high blood pressure caused by hyperactivity of liver-yang and preparation method thereof Expired - Fee Related CN102846740B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152338A (en) * 2006-09-25 2008-04-02 李一龙 Anti-hypertension spray agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152338A (en) * 2006-09-25 2008-04-02 李一龙 Anti-hypertension spray agent

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