CN101297954B - Unbilical medicament for treating cough and preparation thereof - Google Patents

Unbilical medicament for treating cough and preparation thereof Download PDF

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CN101297954B
CN101297954B CN2008100315379A CN200810031537A CN101297954B CN 101297954 B CN101297954 B CN 101297954B CN 2008100315379 A CN2008100315379 A CN 2008100315379A CN 200810031537 A CN200810031537 A CN 200810031537A CN 101297954 B CN101297954 B CN 101297954B
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parts
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medicine
cover
rhizoma
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CN101297954A (en
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李德敏
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Abstract

The invention discloses an umbilicus applying drug for the treatment of tussis, and a preparation method thereof. The medicament of the invention is prepared by raw materials with the following weight portions: 10 to 20 portions of flos farfarae, 10 to 20 portions of rhizoma pinelliae, 10 to 25 portions of herba ephedrae, 4 to 8 portions of fructus papaveris, 4 to 8 portions of fructus schizandrae, 4 to 8 portions of asarum, 0.5 to 1.5 portions of erythromycin, 0.01 to 0.03 portions of chlortrimeton, 0 to 16 portions of cassia twig and 0 to 16 portions of radix paeoniae alba, etc. The Chinese medicine raw materials are firstly put into a pot according to portions, then added with water to cover the Chinese medicine, heated up and boiled for 5 minutes to 8 minutes, and cooled to obtain liquid medicine; the Chinese medicine materials are repeatedly decocted for 2 times to 3 times, and the liquid medicine is filtered after being mixed to be condensed into paste; the erythromycin and the chlortrimeton are added, 3 percent of sodium benzoate are added for antisepsis, and 1 percent of honey or vaseline is prepared to be refined into plaster. About 2g plaster is placed at the center of an applying cloth which is 8 multiplied by 5cm, and coated by a film. The umbilicus applying drug of the invention can treat various non-organic tussis caused by cold, allergen and mycoplasma infection, etc. and can be plastered on the umbilicus in the onset of a cold, with faster effect and safe medication and no toxic and side effect.

Description

The cover-navel medicine and the preparation method of treatment cough
Technical field
The present invention relates to a kind of cover-navel medicine for the treatment of cough, add Western medicine by the Chinese medicine mixing and make plaster.
The invention still further relates to the preparation method of this medicine.
Background technology
Cough is a kind of common frdquently encountered disease, and comparatively common have cough and a cough allergic asthma that causes because of cough, allergic cough, mycoplasma infection that flu causes.Usually the method for handling above-mentioned cough is: antiinflammatory adds agent or the propellant etc. of reducing phlegm of relievining asthma.Bad because of the oral drugs absorption, because of southern therapeutic effect owes satisfied, and treatment time is longer relatively.Therefore, treat the medicine of cough and the extensive concern that technology also is subjected to medical circle always.Consult contemporary pharmacopeia, the medicine of treatment cough has ketelin capsule, JIZHI TANGJIANG, Chinese ephedra and almond containing cough stopping syrup, carbetapentane citrate tablet, capital of a country MILIAN CHUANBEI PIPA GAO etc., and these all are the medicines that oral administration is treated cough.Consult relevant patent documentation, application number is that 200510123780.X discloses a kind of acupoint selection strapping medicine and compound method thereof for the treatment of chronic bronchitis, bronchial asthma, mainly is made up of drug components such as Rhizoma Dioscoreae Nipponicae, Moschus, Rhizoma Pinelliae Preparata, Arisaema Cum Bile, Herba Asari, Semen Sinapis Albae, Radix Kansuis; Through pulverizing, sieve and make medicated powder and Rhizoma Zingiberis Recens juice, azone are mixed with paste by 5: 1: 0.3 weight proportions.Medicine differentiation of symptoms and signs for classification of syndrome of the present invention is in conjunction with point selection treatment based on syndrome differentiation medicine application method treatment cough, asthma, the purpose that reaches regulating yin and yang, resists pathogenic factor by stimulating acupoint, dredging the meridian, QI and blood regulating, by the dispersing of medicine, walk to scurry, percutaneous absorbs, and makes the medicine sick institute that go directly, brings into play pharmacological action.
Summary of the invention
The purpose of this invention is to provide a kind of cover-navel medicine for the treatment of cough.Another purpose provides the preparation method of this medicine.
The objective of the invention is to be achieved through the following technical solutions: cover-navel medicine is the medicament of being made by the following weight proportion raw material:
10~20 parts of Flos Farfaraees, 10~20 parts of the Rhizoma Pinelliaes, 10~25 parts in Herba Ephedrae, 4~8 parts on foxtail millet shell,
4~8 parts of Fructus Schisandrae Chinensis, 4~8 parts of Herba Asaris, 0.5~1.5 part in erythromycin, 0.01~0.03 part of chlorphenamine,
0~16 part of Ramulus Cinnamomi, 0~16 part of the Radix Paeoniae Alba, 0~6 part of Rhizoma Zingiberis, 0~6 part of Rhizoma Belamcandae, 0~6 part in Radix Glycyrrhizae.
Preparation method is: earlier raw material of Chinese medicine is put into jar by deal, add water cover and live Chinese medicine, heat and boil 5~8 parts of clocks, the cooling taking liquid; Decoct repeatedly 2~3 times, with medicinal liquid mixing after-filtration, reconcentration becomes cream; Add erythromycin, chlorphenamine, the sodium benzoate of adding 3% is anticorrosion, transfers Mel or vaseline with 1% to be refined into plaster again.The about 2g of ointment is placed the central authorities of applying ointment or plaster of 8 * 5cm, cover with thin film.Place aeration-drying place preservation.
The present invention has following good effect: can treat various because of the cough of non-organics such as flu, anaphylactogen, mycoplasma infection.Cough is affixed on the umbilicus place and gets final product from the beginning of removing thin film, subsides in a day.Instant effect, curative effect is sure, and drug safety has no side effect.
The clinical observation on the therapeutic effect of cover-navel medicine treatment cough 60 examples:
(1) physical data
Observe 120 routine patients altogether, patient's symptom is cough, expectoration or first dry cough or a small amount of sputum crudum.Serious companion's dyspnea, uncomfortable in chest or asthma.Sign has respiratory murmur to increase thick or hears to reach and do moist rale or be dispersed in dried moist rale, and part has wheezing sound.Be divided into two groups at random, every group 60 example.60 examples are organized in treatment, 3 months to 76 years old age, 38 years old mean age; Matched group 60 examples, 2 months to 75 years old age, 37 years old mean age.Be a week course of treatment.
(2) Therapeutic Method
Two groups of all oral Roxithromycins of patient give antiinflammatory, and the adult produces roxithromycin capsules with Zhejiang, and children's produces the Roxithromycin granule with Tianjin.The JIZHI TANGJIANG that relieving cough and removing sputum all produces with Tai Ji group, dose by specification regulation.The treatment group adds cover-navel medicine and applies ointment or plaster at the umbilicus place.
(3) efficacy determination and therapeutic effect
1, criterion of therapeutical effect: the complete obiteration of patient's symptom and sign is for curing; Patient's symptom and sign partly disappears for turning for the better by and large; It is invalid that patient treatment front and back symptom and sign does not have significant change.
2, therapeutic outcome: see the following form.Treatment group total effective rate is 86.7%, and the matched group effective percentage is 56.7%, two group relatively has notable difference (P<0.05) to illustrate that treatment group curative effect obviously is better than matched group.
The Comparison of therapeutic table
Group example number is cured enabledisable total effective rate (%)
Treatment organizes 60 36 16 8 86.7
Matched group 60 18 16 26 56.7
3, untoward reaction: 2 examples are arranged with after applying 3 subsides of umbilicus plaster in the treatment group, pasting the medicine position has slight pruritus and redness, the pruritus redness occurs after 1 routine application 1 is pasted, the above-mentioned untoward reaction disappearance in the back of stopping using.
4, discussion: using and applying umbilicus (SHENQUE acupoint) treatment cough is to use academic principle of motherland's tradition meridian point and blood in the pulmonary circulation rule, medicine is affixed on SHENQUE acupoint, with ionic species by channels and collaterals running to pulmonary, performance is eliminated the phlegm, and wet dissipation, calmness are allayed excitement, poly-unit consolidates, the effect of lung qi dispersing cough-relieving.Simultaneously; medicine is by umbilical part skin; after going into blood capillary, subcutaneous tissue imports umbilical vein; going into liver by portal vein (has avoided because of the rapid elimination effect of oral drugs at liver; make the unlikely reduction of drug effect) flow to heart to pulmonary circulation through postcava again; act on each gas official of body, bronchus and target organ; that suppresses each gas official, bronchial mucosa organizes congestion and edema, glandular secretion; promote body of gland and lung dirt to discharge rapidly; protection gas official, tubular breathing passage are steadily unobstructed, separate degasification official, bronchospasm.Work along both lines by above-mentioned, treat variously rapidly, reach the inner disease outer treat that the traditional Chinese medical science thinks, the effect of eliminating pathogen for dispersing lung-QI because of non-organics such as flu, anaphylactogen, mycoplasma infection coughs.
Pharmacodynamic analysis: Herba Ephedrae has the relieving asthma effect of diuresis of diaphoresis, the effect of Rhizoma Pinelliae removing dampness and eliminating phlegm stopping nausea and vomiting by lowering the adverse flow of QI, and the Flos Farfarae eliminating phlegm and stopping cough can be described as monarch drug; The Ramulus Cinnamomi warming the meridian that induces sweat, the effect that Herba Asari dispersing cold for relieving pain, Rhizoma Belamcandae have the heat clearing away sending down the abnormal ascending QI to remove expectorant, the Rhizoma Zingiberis Recens warming middle-JIAO eliminates the phlegm, and can be described as ministerial drug; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver pain relieving, and Fructus Schisandrae Chinensis has the calm the nerves effect of hidroschesis of the nourishing kidney of astringing the lung, but foxtail millet shell tranquillizing and allaying excitement can be described as adjuvant drug, and Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI heat-clearing and toxic substances removing coordinating the actions of various ingredients in a prescription, can be described as messenger drug.The right effect that nourishing the lung to loosen bowels is arranged with Mel of transferring.Erythromycin is macrolide antibiotic, has to suppress the synthetic of bacterioprotein, and chlorphenamine is the H1 receptor blocking agent, has antianaphylactic effect.
The cooperation of said medicine, thus make the effect of medicine and curative effect more effective, and it is more thorough, more lasting to calm down symptom, also explores more convenient, quick, an effective new method for the treatment cough.
The specific embodiment
Embodiment 1, choose 10~20 parts of Chinese medicine Flos Farfaraees, 10~20 parts of the Rhizoma Pinelliaes, 10~25 parts in Herba Ephedrae, 4~8 parts on foxtail millet shell, 4~8 parts of Fructus Schisandrae Chinensis, 4~8 parts of Herba Asaris, 0~16 part of Ramulus Cinnamomi, 0~16 part of the Radix Paeoniae Alba, 0~6 part of Rhizoma Zingiberis, 0~6 part of Rhizoma Belamcandae, 0~6 part in Radix Glycyrrhizae.Earlier raw material of Chinese medicine is put into jar by deal, add water cover and live Chinese medicine, heat and boil 5~8 parts of clocks, the cooling taking liquid; Decoct repeatedly 2~3 times, with medicinal liquid mixing after-filtration, reconcentration becomes cream; Add 0.5~1.5 part in erythromycin, 0.01~0.03 part of chlorphenamine, the sodium benzoate of adding 3% is anticorrosion, and 1% adding Mel or the vaseline by the ointment total amount is refined into plaster again.The about 2g of ointment is placed the central authorities of applying ointment or plaster of 8 * 5cm, cover with thin film.Place aeration-drying place preservation.
Embodiment 2, choose each 18 parts of Chinese medicine Flos Farfaraees, the Rhizoma Pinelliae, Herba Ephedrae, foxtail millet shell, Fructus Schisandrae Chinensis, Herba Asari each, each 6 parts in Radix Glycyrrhizae.Add 1.2 parts in erythromycin, 0.03 part of chlorphenamine.Preparation method is the same.
Embodiment 3, choose each 15 parts of Chinese medicine Flos Farfaraees, the Rhizoma Pinelliae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Herba Ephedrae, each 5 parts on foxtail millet shell, Fructus Schisandrae Chinensis, Rhizoma Zingiberis, Herba Asari, Rhizoma Belamcandae, Radix Glycyrrhizae.Add 1 part in erythromycin, 0.02 part of chlorphenamine.Preparation method is the same.
Suitable cough, the allergic cough who causes because of flu of this ointment, cough that is caused by mycoplasma infection and cough allergic asthma etc. (except dense swollen, the cough that bronchiectasis causes of lung) are in addition, also can be used for chronic bronchitis, bronchial asthma, during use, remove thin film, be affixed on that (SHENQUE acupoint) gets final product on the umbilicus.

Claims (4)

1. treat the cover-navel medicine of cough, it is characterized in that it is the medicament of being made by the following weight proportion raw material:
10~20 parts of Flos Farfaraees, 10~20 parts of the Rhizoma Pinelliaes, 10~25 parts in Herba Ephedrae, 4~8 parts on foxtail millet shell,
4~8 parts of Fructus Schisandrae Chinensis, 4~8 parts of Herba Asaris, 0.5~1.5 part in erythromycin, 0.01~0.03 part of chlorphenamine,
0~16 part of Ramulus Cinnamomi, 0~16 part of the Radix Paeoniae Alba, 0~6 part of Rhizoma Zingiberis, 0~6 part of Rhizoma Belamcandae, 0~6 part in Radix Glycyrrhizae.
2. the cover-navel medicine of treatment cough according to claim 1 is characterized in that it is the medicament of being made by the following weight proportion raw material:
15 parts of Flos Farfaraees, 15 parts of the Rhizoma Pinelliaes, 15 parts in Herba Ephedrae, 5 parts on foxtail millet shell,
5 parts of Fructus Schisandrae Chinensis, 5 parts of Herba Asaris, 1 part in erythromycin, 0.02 part of chlorphenamine,
15 parts of Ramulus Cinnamomi, 15 parts of the Radix Paeoniae Albas, 5 parts of Rhizoma Zingiberiss, 5 parts of Rhizoma Belamcandae, 5 parts in Radix Glycyrrhizae.
3. the cover-navel medicine of treatment cough according to claim 1 and 2 is characterized in that medicine is the paste patch.
4. the preparation method of the cover-navel medicine of claim 1 or 2 described treatment coughs is characterized in that, earlier raw material of Chinese medicine is put into jar according to quantity, add water cover and live Chinese medicine, heat and boil 5~8 minutes, the cooling taking liquid, decoct taking liquid repeatedly 2~3 times, with medicinal liquid mixing after-filtration, reconcentration becomes cream; Add erythromycin, chlorphenamine, the sodium benzoate of adding 3% is anticorrosion, transfers Mel or vaseline with 1% to be refined into plaster again.
CN2008100315379A 2008-06-13 2008-06-13 Unbilical medicament for treating cough and preparation thereof Expired - Fee Related CN101297954B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823624A (en) * 2017-12-19 2018-03-23 李宁 A kind of plaster
CN109010536A (en) * 2018-09-12 2018-12-18 赖庭荣 A kind of plaster for cold and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103589A (en) * 1993-12-09 1995-06-14 卜荣安 Plaster for treating respiratory system diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103589A (en) * 1993-12-09 1995-06-14 卜荣安 Plaster for treating respiratory system diseases

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