CN102823606B - Acaricidal composition containing bifenazate - Google Patents
Acaricidal composition containing bifenazate Download PDFInfo
- Publication number
- CN102823606B CN102823606B CN201210360484.1A CN201210360484A CN102823606B CN 102823606 B CN102823606 B CN 102823606B CN 201210360484 A CN201210360484 A CN 201210360484A CN 102823606 B CN102823606 B CN 102823606B
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- CN
- China
- Prior art keywords
- bifenazate
- propargite
- mite
- pyridaben
- avermectin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
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Abstract
The invention discloses an acaricidal composition containing bifenazate. Active ingredients comprise the bifenazate and propargite, and the weight ratio of the bifenazate to the propargite is (0.125-0.5): 1. The acaricidal composition has the advantages of being reasonable in components, good in acaricidal effect and low in medication cost, the activity and the insecticidal effect are not obtained by easy superposition of the activities of the components, the significant synergy is realized, and the acaricidal composition further has the effects of high rapid acting, long lasting effect, capability of slowing down the generation of resistance and good safety for crops, and is also can meet the safety requirements of pesticide preparations. The acaricidal composition disclosed by the invention can be used for preparing water dispersible granules, suspension concentrate, wettable powder, and missible oil or aqueous emulsion formulations so as to be used for controlling citrus red mites, European red mites and mites on cotton crops.
Description
Technical field
The present invention relates to a kind of miticide composition, particularly a kind of Bifenazate is as the first active component, and Avermectin, pyridaben or propargite, as miticide composition and the application thereof of the second active component, belong to technical field of compounded pesticide.
Background technology
Bifenazate english common name bifenazate, chemical molecular formula C
17h
20n
2o
3.Bifenazate is a kind of γ-aminobutyric acid (GABA) antagonist, mainly prevents and treats active stage tetranychid, and quick-acting is good, if to young mite with to become mite effective, to some other mite classes, especially Tetranychus urticae is had to ovicidal action.Experimental study shows, Bifenazate does not have negative effect to predatism benefit mite; To the low (LD of mammalian toxicity
50be 5 000mg/kg); Lasting period short (DT50<1d) in environment.The Bifenazate of selling is in the market the suspending agent of 480 grams per liters, is mainly used in preventing and treating apple tree two spotted spider mite.As a kind of new hydrazine ester class specialty miticide, it is high that Bifenazate in use exists use cost, the risk that resistance increases gradually, the defect that lasting period is short, and it is rationally mixed with dissimilar miticide, for fully effectively promoting Bifenazate, extend its service life and there is important function.
Avermectin, has another name called acarid element, acetamiprid, and the evil utmost point goes out, desinsection fourth, english common name fabamectin, chemical molecular formula C
48h
72o
14(B1a) C
47h
70o
14(B1b), be a kind of macrolide disaccharide compounds.Be natural products separated from edaphon, insects and mites had and tags with stomach poison function and have faint fumigation action, without systemic action.But it has very strong osmosis to blade, can kill subepidermal insect, and the longevity of residure is long.It is ovicidal not.What its mechanism of action was different from general insecticide is that it disturbs neurophysiology movable, stimulates and discharges
r-aminobutyric acid, and
r-aminobutyric acid has inhibitory action to arthropodan nerve conduction, if mite class occurs paralysis symptom after becoming mite to contact with medicament with larva with insect, inertia does not take food, dead after 2-4 days.Because not causing that insect dewaters rapidly, so its lethal effect is slower.But though predatism and parasite are had to direct killing effect, because plant surface is residual few, therefore little to the damage of beneficial insect.But as a kind of miticide of long-term use, Avermectin has produced resistance in various degree in long-term use procedure, has control efficiency decline defect.
Pyridaben, has another name called pyridaben, pyridaben, and the mite of rattling away is clean, english common name pyridaben, molecular formula C
19h
25clN
2oS.Pyridaben is wide spectrum, tagging property miticide, can be used for preventing and treating multiple food vegetalitas evil mite.If to being the whole vegetative period of mite ovum, young mite mite and becoming mite to have good effect, to the one-tenth mite of mobile phase, there is equally obvious speed to kill effect.This medicine is not acted upon by temperature changes, and no matter uses in early spring or autumn, all can reach promising result.But pyridaben is longer service time, and resistance increases gradually.
Propargite, has another name called Aomei spy, propargite, english common name propargite, molecular formula C
19h
26o
4s.Propargite is low toxicity broad spectrum activity organosulfur acaricide, has and tags and stomach poison function, without interior suction and infiltration conduction, if to becoming mite mite effective, the weak effect of ovicidal, this medicine temperature more than 20 ℃ under condition drug effect can improve, but below 20 ℃, with low temperature, falling progressively, propargite can be used for preventing and treating cotton, vegetables, apple, citrus, tea, the harmful mite of the various crop such as flowers, safer to most natural enemies, but want strict controlled concentration, too high easy generation poisoning while using on tender little crop.Propargite is as a kind of miticide of long-term use, and service time is longer, and resistance increases gradually, without ovicidal effect.
At present, the pesticidal preparations that the Bifenazate of take is effective ingredient be take 480 grams per liter Bifenazate suspending agents as main, and in actual use, quick-acting is good, but lasting effect is general, and use cost is high; Avermectin, pyridaben and propargite are as domestic conventional miticide kind, miticidal effect and cost performance are user all the time and accept, but resistance is rising year by year, inventor surprisingly finds the use that is mixed of Bifenazate and Avermectin, pyridaben or propargite, there is significant synergistic effect, can reduce use cost, slow down the generation of pest resistance.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, significantly synergy, miticidal effect is good, and drug cost is low, the miticide composition containing Bifenazate that is difficult for developing immunity to drugs.
Another object of the present invention is to provide the application containing the miticide composition of Bifenazate.
In order to overcome the defect of existing unitary agent, technical scheme of the present invention is to solve like this:
Miticide composition containing Bifenazate, comprising:
A) the first active component Bifenazate;
B) the second active component Avermectin, pyridaben or propargite;
The weight ratio of the first active component and the second active component is: Bifenazate and Avermectin are (5 ~ 40): 1; Bifenazate and pyridaben are (0.5 ~ 8): 1; Bifenazate and propargite are (0.125 ~ 0.5): 1.
The cumulant of the first active component and the second active component is 5%～90% of described composition total weight, is preferably 10%～50%, and the size of active component cumulant is also closely related with formulation, as the active component cumulant of suspending agent is no more than 50%.
The preparation formulation that the present invention can prepare according to the known method of those skilled in the art of the present technique containing the miticide composition of Bifenazate is water dispersible granules, suspending agent, wetting powder, missible oil or aqueous emulsion.
For water dispersible granules, those skilled in the art are familiar with the corresponding auxiliary agent of use and complete the present invention very much.Dispersant as in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate one or more; Wetting agent as in alkyl sulfate, alkylsulfonate, naphthalene sulfonate one or more; Disintegrant as in ammonium sulfate, urea, sucrose, glucose one or more; Binding agent is as one or more in diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family; Filler as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To suspending agent, spendable auxiliary agent has: dispersant is produced as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, TERSPERSE 2425(U.S. Huntsman Corporation, alkyl naphthalene sulfonic acid salt) in one or more; Emulsifier is as Nongru-700 #(common name: alkyl phenol formaldehyde resin polyoxyethylene ether, agriculture breast 2201, this dish-60#(common name sorbitan monostearate), emulsifier T-60(common name: sorbitan monostearate APEO), agriculture breast 1601#(common name: phenethyl phenol polyoxyethylene poly-oxygen propylene aether), TERSPERSE 4894(U.S. Huntsman Corporation produces) TERSPERSE 2500(U.S. Huntsman Corporation produces) in one or more; Wetting agent is produced as alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500(U.S. Huntsman Corporation) in one or more; Thickener as in xanthans, polyvinyl alcohol, bentonite one or more; Preservative as in formaldehyde, benzoic acid, Sodium Benzoate one or more; Defoamer is as organic silicon defoamer; Antifreezing agent as ethylene glycol, propane diols, glycerine, urea, inorganic salts as in sodium chloride one or more.
To wetting powder, spendable auxiliary agent has: dispersant as in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate one or more; Wetting agent as in alkyl sulfate, alkylsulfonate, naphthalene sulfonate one or more; Filler as ammonium sulfate, urea, sucrose, glucose diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
For missible oil, spendable auxiliary agent has: emulsifier is as calcium dodecyl benzene sulfonate (agriculture breast 500#), Nongru-700 #(common name: alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201#, Span-60#(common name sorbitan monostearate), emulsifier T-60(common name: sorbitan monostearate APEO), TX-10(common name: octyl phenol polyoxy ethene (10) ether), agriculture breast 1601#(common name: phenethyl phenol polyoxyethylene poly-oxygen propylene aether), in agriculture breast 600#, agriculture breast 400# one or more; Solvent as in dimethylbenzene, solvent naphtha (S-150, S-180, S-200), toluene, methyl alcohol, dimethyl formamide, cyclohexanone, acetone, diesel oil one or more; Stabilizing agent as in triphenyl phosphite, epoxychloropropane, aceticanhydride one or more.
To aqueous emulsion, spendable auxiliary agent has: emulsifier is as Nonyl pheno (EO=10) ether phosphate, triphen ethyl-phenol polyoxyethylene ether phosphate (agriculture breast 600# phosphate), Nongru-700 #(common name: alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201#, Span-60#(common name sorbitan monostearate), emulsifier T-60(common name: sorbitan monostearate APEO), TX-10(common name: octyl phenol polyoxy ethene (10) ether), agriculture breast 1601(common name: phenethyl phenol polyoxyethylene poly-oxygen propylene aether), agriculture breast 600#, in agriculture breast 400# one or more, solvent as dimethylbenzene, toluene, solvent naphtha (trade mark: S-150, S-180, S-200) one or more, stabilizing agent as in triphenyl phosphite, epoxychloropropane, aceticanhydride one or more, antifreezing agent: ethylene glycol, propane diols, glycerine, urea, inorganic salts as in sodium chloride one or more, thickener as in xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate one or more, preservative as in formaldehyde, benzoic acid, Sodium Benzoate one or more.
Component of the present invention is reasonable, and miticidal effect is good, and drug cost is low, and its activity and insecticidal effect are not the simple superposition of each composition activity, but have significant synergistic effect, and quick-acting is high, lasting effect is long, slow down the generation of resistance, good to crop safety, meet the security requirement of pesticidal preparations.The present invention has good control efficiency to the mite class on citrus red mite, European red mite, cotton crop.
Embodiment
In order to prevent and treat the insects such as citrus red mite in agricultural production, inventor has carried out mutual composite synergy research with compositions such as Bifenazate, Avermectin, pyridaben and propargites.It is tested object that test adopts citrus red mite, and concrete grammar is: citrus red mite (panonychus citri, formal name used at school
panonychus citfimcGregor) the former medicine that the former medicine of test medicine Bifenazate adopts U.S. Chemtura Corporation to produce, the former medicine that the former medicine of Avermectin adopts Zhejiang Hisun Chemical Co., Ltd to produce, the former medicine that the former medicine of pyridaben adopts Kesheng Group Co., Ltd., Jiangsu Prov. to produce, the former medicine that propargite medicine adopts Zhejiang Prov HeBen pesticide Chemical Co., Ltd to produce, test method is with reference to the agricultural industry criteria NY/T1282-2007 > > of the < < People's Republic of China (PRC).First single dose and each Mixed Pharmacy are arranged to 5 variable concentrations gradients (on the basis of preliminary experiment result, citrus red mite becomes mite lethality to set by geometric progression in 5%～90% scope).Examination worm is the one-tenth mite of picking up from field, in laboratory, select the one-tenth mite of uniformity in the length of time, put into blade-carrying culture dish, every ware 40 cephalont, 4 culture dishes of every processing, repeat 3 times, with potter spray tower, under 50PSI pressure, spray, spray a ware at every turn, every ware spraying liquid 3ml, then the culture dish of processing is put into 12H/12H illumination box and cultivate, within 48 hours, check dead borer population, calculate lethality.Blank spray equivalent clear water.
The co-toxicity coefficient of mixture (CTC value) calculates by following formula:
ATI-mixture actual measurement toxicity index;
S-standard insecticide LC
50, unit is milligrams per liter (mg/L);
The LC of M-mixture
50, unit is milligrams per liter (mg/L);
TTI=TI
a* P
a+ TI
b* P
b, in formula:
The theoretical toxicity index of TTI-mixture;
TI
a-A medicament toxicity index;
P
athe percentage composition of-A medicament in mixture, unit is percentage (%);
TI
b-B medicament toxicity index;
P
bthe percentage composition of-B medicament in mixture, unit is percentage (%);
CTC-co-toxicity coefficient;
ATI-mixture actual measurement toxicity index;
The theoretical toxicity index of TTI-mixture;
The co-toxicity coefficient of complex preparation (CTC) >=120 shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
2) measurement result of citrus red mite is respectively in Table A, table B, table C.
Toxicity Determination result shows: Bifenazate is respectively mixed and becomes mite to have good toxic effect to citrus red mite with Avermectin, pyridaben and propargite, and Bifenazate and Avermectin are (5 ~ 40): 1; Bifenazate and pyridaben are (0.5 ~ 8): 1; Bifenazate and propargite are (0.125 ~ 0.5): between 1, all have remarkable synergistic effect.
Below in conjunction with specific embodiment, content of the present invention is described further.
fORMULATION EXAMPLE 1:
Taking mass percent is 40% Bifenazate, 8% Avermectin, 3% TERSPERSE 2700(polycarboxylate, and U.S. Huntsman Corporation produces), 2% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 2%K-12(lauryl sodium sulfate), 3% White Carbon black, 5% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 48% Bifenazate Avermectin water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 48%, form new embodiment.
fORMULATION EXAMPLE 2:
Take 40% Bifenazate, 4% Avermectin, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 2% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 2% K-12(lauryl sodium sulfate), 3% White Carbon black, 5% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 44% Bifenazate Avermectin water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 44%, form new embodiment.
fORMULATION EXAMPLE 3:
Take 40% Bifenazate, 1% Avermectin, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 4% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 5% K-12(lauryl sodium sulfate), 3% White Carbon black, 5% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 41% Bifenazate Avermectin water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 41%, form new embodiment.
fORMULATION EXAMPLE 4:
Take 60% Bifenazate, 3% Avermectin, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 2% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 2% K-12(lauryl sodium sulfate), 3% White Carbon black, 5% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 63% Bifenazate Avermectin water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 63%, form new embodiment.
fORMULATION EXAMPLE 5:
Take 40% Bifenazate, 10% pyridaben, 4% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 4%K-12(lauryl sodium sulfate), 3% White Carbon black, 8% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 50% Bifenazate pyridaben water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (0.5 ~ 8): between 1, change, both total weight items are still 50%, form new embodiment.
fORMULATION EXAMPLE 6:
Take 40% Bifenazate, 20% pyridaben, 4% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 4%K-12(lauryl sodium sulfate), 3% White Carbon black, 8% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 60% Bifenazate pyridaben water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (0.5 ~ 8): between 1, change, both total weight items are still 60%, form new embodiment.
fORMULATION EXAMPLE 7:
Take 40% Bifenazate, 5% pyridaben, 3% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 2% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 2% K-12(lauryl sodium sulfate), 3% White Carbon black, 5% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 45% Bifenazate Avermectin water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (5 ~ 40): between 1, change, both total weight items are still 45%, form new embodiment.
fORMULATION EXAMPLE 8:
Take 20% Bifenazate, 40% pyridaben, 4% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% Nekal BX (nekal), 4%K-12(lauryl sodium sulfate), 3% White Carbon black, 8% sulphur ammonium, diatomite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 60% Bifenazate pyridaben water dispersible granules.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (0.5 ~ 8): between 1, change, both total weight items are still 60%, form new embodiment.
fORMULATION EXAMPLE 9:
Taking 40% Bifenazate, 2% Avermectin, 3%TERSPERSE 4894(U.S. Huntsman Corporation produces), 2%TERSPERSE 2500(U.S. Huntsman Corporation produces), 3%TERSPERSE 2425(U.S. Huntsman Corporation produces), 0.2% xanthans, 3% white carbon, 5% ethylene glycol, 0.3% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces) deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with the Bifenazate Avermectin suspending agent that makes 42% after sand mill sand milling.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 42%, form new embodiment.
fORMULATION EXAMPLE 10:
Taking 30% Bifenazate, 2% Avermectin, 3%TERSPERSE 4894(U.S. Huntsman Corporation produces), 2%TERSPERSE 2500(U.S. Huntsman Corporation produces), 3%TERSPERSE 2425(U.S. Huntsman Corporation produces), 0.2% xanthans, 3% white carbon, 5% ethylene glycol, 0.3% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces) deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with the Bifenazate Avermectin suspending agent that makes 32% after sand mill sand milling.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 32%, form new embodiment.
fORMULATION EXAMPLE 11:
Taking 30% Bifenazate, 10% pyridaben, 3%TERSPERSE 4894(U.S. Huntsman Corporation produces), 1.5%TERSPERSE 2500(U.S. Huntsman Corporation produces), 3%TERSPERSE 2425(U.S. Huntsman Corporation produces), 0.15% xanthans, 5% white carbon, 5% ethylene glycol, 0.3% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces) deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with the Bifenazate Damanling suspension agent that makes 40% after sand mill sand milling.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (0.5 ~ 8): between 1, change, both total weight items are still 40%, form new embodiment.
fORMULATION EXAMPLE 12:
Taking 30% Bifenazate, 15% pyridaben, 3%TERSPERSE 4894(U.S. Huntsman Corporation produces), 1.5%TERSPERSE 2500(U.S. Huntsman Corporation produces), 3%TERSPERSE 2425(U.S. Huntsman Corporation produces), 0.15% xanthans, 5% white carbon, 5% ethylene glycol, 0.3% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29, Nanjing "four news" (new ideas applied chemistry product company produces) deionized water add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with the Bifenazate Damanling suspension agent that makes 45% after sand mill sand milling.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (0.5 ~ 8): between 1, change, both total weight items are still 45%, form new embodiment.
fORMULATION EXAMPLE 13:
Take 30% Bifenazate, 2% Avermectin, 5% calcium lignosulfonate, 2% Nekal BX (nekal), 2%K-12(lauryl sodium sulfate), 5% White Carbon black, kaolin add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 32% Bifenazate Avermectin wetting powder after air-flow crushing.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 32%, form new embodiment.
fORMULATION EXAMPLE 14:
Take 60% Bifenazate, 20% pyridaben, 5% calcium lignosulfonate, 2% Nekal BX (nekal), 1%K-12(lauryl sodium sulfate), 3% White Carbon black, kaolin add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 80% Bifenazate pyridaben wetting powder after air-flow crushing.
In the present embodiment, the part by weight of Bifenazate and pyridaben can be in (0.5 ~ 8): between 1, change, both total weight items are still 80%, form new embodiment.
fORMULATION EXAMPLE 15:
Take 15% Bifenazate, 30% propargite, 4% agriculture breast 500#, 2% agriculture breast 600#, 3% agriculture breast 2201#, 3% triphenyl phosphite, 15% cyclohexanone, solvent naphtha S-180 add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 45% Bifenazate propargite missible oil after stirring and dissolving is complete.
In the present embodiment, the part by weight of Bifenazate and propargite can be in (0.125 ~ 0.5): between 1, change, both total weight items are still 45%, form new embodiment.
fORMULATION EXAMPLE 16:
Take 10% Bifenazate, 40% propargite, 5% agriculture breast 500#, 2% agriculture breast 400#, 3% Nongru-700 #, 2% epoxychloropropane, 10% cyclohexanone, dimethylbenzene add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 50% Bifenazate propargite missible oil after stirring and dissolving is complete.
In the present embodiment, the part by weight of Bifenazate and propargite can be in (0.125 ~ 0.5): between 1, change, both total weight items are still 50%, form new embodiment.
fORMULATION EXAMPLE 17:
Take 30% Bifenazate, 1.5% Avermectin, 3% agriculture breast 2201#, 2% Nonyl pheno (EO=10) ether phosphate, 2% triphen ethyl-phenol polyoxyethylene ether phosphate (agriculture breast 600# phosphate), 2%Span-60#, 1% epoxychloropropane, 5% ethylene glycol, 25% dimethylbenzene, 0.3% xanthans, 0.5% benzoic acid, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear emulsification makes 31.5% Bifenazate abamectin aqueous emulsion.
In the present embodiment, the part by weight of Bifenazate and Avermectin can be in (5 ~ 40): between 1, change, both total weight items are still 31.5%, form new embodiment.
fORMULATION EXAMPLE 18:
Take 10% Bifenazate, 25% propargite, 3% agriculture breast 2201#, 1.5% Nonyl pheno (EO=10) ether phosphate, 2.5% triphen ethyl-phenol polyoxyethylene ether phosphate (agriculture breast 600# phosphate), 2%Span-60#, 1% epoxychloropropane, 5% ethylene glycol, 20% dimethylbenzene, 0.3% xanthans, 0.5% benzoic acid, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear emulsification makes 35% Bifenazate propargite aqueous emulsion.
In the present embodiment, the part by weight of Bifenazate and propargite can be in (0.125 ~ 0.5): between 1, change, both total weight items are still 35%, form new embodiment.
biological Examples 1: control citrus red mite field trial
In Deqing County, Zhaoqing City of Guangdong Province, carried out the field control effectiveness test of 32% Bifenazate Avermectin (30+2) suspending agent control citrus red mite of FORMULATION EXAMPLE 10, verified that this medicament is to the control efficiency of citrus red mite, effective dose and the safety to mandarin tree.Trial crops is oranges and tangerines, controlling object citrus red mite (
panonychus citri Me Gregor).Test medicine and dosage are 2000 times, 3000 times, 4000 times of 32% Bifenazate Avermectin suspending agents, and 480g/ rises 2000 times of Bifenazate suspending agents, and 2% 1500 times of abamectin emulsifiable concentrates, adopt conventional spray-on process.Investigation insect population radix before dispenser, after medicine, 3d, 7d, 14d, 30d, 45d investigate respectively residual borer population alive, and 2 strains are looked in investigation Shi Mei community, every strain is looked into respectively 5 leaves by orientation, 4 of the four corners of the world, every community is looked into 40 leaves altogether, records the mite number of living, and carries out control efficiency statistics.Preventive effect computational methods
，
In formula: Pt
0---before treatment region medicine; Pt
1---after treatment region medicine; CK
0---before the medicine of check plot; CK
1---after the medicine of check plot.
Table 1 carries out biostatistics Epidemiological Analysis for 14Tian Shige community preventive effect after medicine, and analysis result shows: between processing, difference reaches utmost point significance level, and district's group difference is not remarkable.Significance of difference comparative result shows: consistent with the significance of difference in 0.01 level in 0.05 level, 32% 2000 times, 3000 times of Bifenazate Avermectin suspending agents and other each process between difference all reach utmost point significance level, to rise between 2000 times of Bifenazate suspending agents, 1500 times of 3 processing between two of 2% abamectin emulsifiable concentrate comparing difference all not remarkable with contrasting medicament 480g/ for 32% 4000 times of Bifenazate Avermectin suspending agents.
Field trial shows: 32% Bifenazate Avermectin suspending agent has more significant control efficiency to citrus red mite, its 2000 times, the control efficiency of 3000 times is obviously better than contrasting medicament 480g/ and rises 2000 times of Bifenazate suspending agents, the control efficiency of 2% 1500 times of abamectin emulsifiable concentrates, its 4000 times rise 2000 times of Bifenazate suspending agents with 480g/, the control efficiency of 2% 1500 times of abamectin emulsifiable concentrates is substantially suitable, after result of the test shows that Bifenazate and Avermectin are mixed, obviously improved the quick-acting of citrus red mite and lasting period, greatly reduce dosage, to mandarin tree growth safety.
Biological Examples 2: control European red mite field trial
In Liquan County, Shaanxi Province, carried out the field control effectiveness test of 60% Bifenazate pyridaben water dispersible granules (40+20) control European red mite of FORMULATION EXAMPLE 6, verified that this medicament is to the control efficiency of European red mite, effective dose and the safety to apple tree.Trial crops is apple tree, controlling object European red mite (
tetranychus viennensis Zacher).Test medicine and dosage are 5000 times, 6000 times, 7000 times of 60% Bifenazate pyridaben water dispersible granules, and 480g/ rises 3000 times of Bifenazate suspending agents, and 20% 2000 times of pyridaben wetting powders, adopt conventional spray-on process.Investigation insect population radix before dispenser, after medicine, 3d, 7d, 14d, 30d, 45d investigate respectively residual borer population alive, and 2 strains are looked in investigation Shi Mei community, every strain is looked into respectively 5 leaves by orientation, 4 of the four corners of the world, every community is looked into 40 leaves altogether, records the mite number of living, and carries out control efficiency statistics.
Table 2 carries out biostatistics Epidemiological Analysis for 14Tian Shige community preventive effect after medicine, and analysis result shows: between processing, difference reaches extremely outstanding level, and district's group difference is not remarkable.Significance of difference comparative result shows: consistent with the significance of difference in 0.01 level in 0.05 level, between 60% 5000 times, 6000 times of Bifenazate pyridaben water dispersible granules, 7000 times of 3 processing, compare between two difference and all reach utmost point significance level, 3 process all with contrasting medicament 480g/ and rise difference between 3000 times of Bifenazate suspending agents, 2000 times of processing of 20% pyridaben wetting powder and reach utmost point significance level, and contrasting medicament 480g/, to rise between 3000 times of Bifenazate suspending agents and 2000 times of two processing of 20% pyridaben wetting powder difference not remarkable.
Field trial shows: 60% Bifenazate pyridaben water dispersible granules has more significant control efficiency to European red mite, the control efficiency of its 5000 times, 6000 times, 7000 times is obviously better than contrasting the control efficiency that medicament 480g/ rises 3000 times of Bifenazate suspending agents, 2000 times of 20% pyridaben wetting powders, result of the test shows: after Bifenazate and pyridaben are mixed, obviously improved the quick-acting of European red mite and lasting period, dosage and drug cost have been reduced, to Apple Growth safety.
Biological Examples 3: control citrus red mite field trial
In area, Yangjiang, Guangdong Province, carried out the field control effectiveness test of 35% Bifenazate propargite aqueous emulsion (10+25) control citrus red mite of FORMULATION EXAMPLE 18, verified that this medicament is to the control efficiency of citrus red mite, effective dose and the safety to mandarin tree.Trial crops is oranges and tangerines, controlling object citrus red mite (
panonychus citri Me Gregor).Test medicine and dosage are 1000 times, 1500 times, 2000 times of 35% Bifenazate propargite aqueous emulsions, and 480g/ rises 2000 times of Bifenazate suspending agents, and 73% 2000 times of propargite missible oil, adopt conventional spray-on process.Investigation insect population radix before dispenser, after medicine, 3d, 7d, 14d, 30d, 45d investigate respectively residual borer population alive, and 2 strains are looked in investigation Shi Mei community, every strain is looked into respectively 5 leaves by orientation, 4 of the four corners of the world, every community is looked into 40 leaves altogether, records the mite number of living, and carries out control efficiency statistics.
Table 3 carries out biostatistics Epidemiological Analysis for the 7th Tian Shige community preventive effect after medicine, and analysis result shows: between processing, difference reaches extremely outstanding level, and district's group difference is not remarkable.Significance of difference comparative result shows: consistent with the significance of difference in 0.01 level in 0.05 level, 35% 1000 times, 1500 times of Bifenazate propargite aqueous emulsions and other each process between difference all reach utmost point significance level, to rise between 2000 times of Bifenazate suspending agents, 2000 times of processing of 73% propargite missible oil difference not remarkable with contrasting medicament 480g/ for 35% 2000 times of Bifenazate propargite aqueous emulsions.
Field trial shows: 35% Bifenazate propargite aqueous emulsion has more significant control efficiency to citrus red mite, its 1000 times, the control efficiency of 1500 times is obviously better than contrasting medicament 480g/ and rises 2000 times of Bifenazate suspending agents, the control efficiency of 73% 2000 times of propargite missible oil, its 2000 times rise 2000 times of Bifenazate suspending agents with 480g/, the control efficiency of 73% 2000 times of propargite missible oil is substantially suitable, after result of the test shows that Bifenazate and propargite are mixed, obviously improved the control efficiency to citrus red mite, greatly reduce dosage, to mandarin tree growth safety.
Biological Examples 4: control cotton red spider field trial
In the solid town of Shaanxi Province's Weinan City, carried out the field control effectiveness test of 50% Bifenazate propargite missible oil (10+40) control cotton red spider of FORMULATION EXAMPLE 16, verified that this medicament is to the control efficiency of cotton red spider, effective dose and the safety to cotton.Trial crops is cotton, controlling object cotton red spider (Tetranychuscinnabarinus (Boisduval)).Test medicine and dosage are 2000 times, 2500 times, 3000 times of 50% Bifenazate propargite missible oil, and 480g/ rises 3000 times of Bifenazate suspending agents, and 73% 2500 times of propargite missible oil, adopt conventional spray-on process.Investigation insect population radix before dispenser, after medicine, 3d, 7d, 14d, 30d investigate respectively residual borer population alive, and investigation 5 of Shi Mei communities sampling is fixed 2 strain cotton investigation at every, and every strain fixedly upper blade has 5, and the two spotted spider mite number on investigation fixed blade, records the mite number of living.
Table 4 carries out biostatistics Epidemiological Analysis for the 7th Tian Shige community preventive effect after medicine, and analysis result shows: between processing, difference reaches extremely outstanding level, and district's group difference is not remarkable.Significance of difference comparative result shows: consistent with the significance of difference in 0.01 level in 0.05 level, 50% 2000 times, 2500 times of Bifenazate propargite missible oil processing and other each process between difference all reach utmost point significance level, to rise between 3000 times of Bifenazate suspending agents, 2500 times of processing of 73% propargite missible oil difference not remarkable with contrasting medicament 480g/ in its 3000 times of processing.
Field trial shows: 50% Bifenazate propargite missible oil has significant control efficiency to cotton red spider, and the control efficiency of its 2000 times, 2500 times is obviously better than contrasting the control efficiency that medicament 480g/ rises 3000 times of Bifenazate suspending agents, 2500 times of 73% propargite missible oil.Result of the test shows: after Bifenazate and propargite are mixed, obviously improved the quick-acting of cotton red spider and lasting period, reduced dosage and drug cost, to cotton growth safety.
Visible, the present composition adopts two kinds of active component compound schemes, its activity and miticidal effect are not the simple superposition of each composition activity, compare, except having significant miticidal effect with existing unitary agent, and there is a significant synergistic effect, quick-acting is high, lasting effect is long, slows down the generation of resistance, good to crop safety, dosage reduces, and meets the security requirement of pesticidal preparations.
Claims (5)
1. containing a miticide composition for Bifenazate, it is characterized in that: active component is comprised of Bifenazate and propargite, the weight ratio of Bifenazate and propargite is (0.125 ~ 0.5): 1.
2. the miticide composition containing Bifenazate according to claim 1, is characterized in that: the cumulant of Bifenazate and propargite is described composition total weight 5%～90%.
3. the miticide composition containing Bifenazate according to claim 2, is characterized in that: the cumulant of Bifenazate and propargite is described composition total weight 10%～50%.
4. according to one of any described miticide composition containing Bifenazate of claims 1 to 3, it is characterized in that: described composition is water dispersible granules, suspending agent, wetting powder, missible oil or aqueous emulsion.
5. the application of one of any described miticide composition containing Bifenazate of claims 1 to 3 in control citrus red mite, European red mite, cotton red spider.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000002453A1 (en) * | 1998-07-07 | 2000-01-20 | Novartis Ag | Pesticidal composition comprising emamectin |
| CN101489388A (en) * | 2006-07-11 | 2009-07-22 | 拜尔农作物科学股份公司 | Active ingredient combinations with insecticidal and acaricidal properties |
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| WO2000002453A1 (en) * | 1998-07-07 | 2000-01-20 | Novartis Ag | Pesticidal composition comprising emamectin |
| CN101489388A (en) * | 2006-07-11 | 2009-07-22 | 拜尔农作物科学股份公司 | Active ingredient combinations with insecticidal and acaricidal properties |
Non-Patent Citations (1)
| Title |
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| 仵均祥.棉花害螨.《农业昆虫学》.中国农业出版社,2003,第170-171页. * |
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