CN102811610B - 无刺激性眼科聚维酮碘组合物 - Google Patents

无刺激性眼科聚维酮碘组合物 Download PDF

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Publication number
CN102811610B
CN102811610B CN201080057483.9A CN201080057483A CN102811610B CN 102811610 B CN102811610 B CN 102811610B CN 201080057483 A CN201080057483 A CN 201080057483A CN 102811610 B CN102811610 B CN 102811610B
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CN
China
Prior art keywords
approximately
preparation
ophthalmic preparation
pvp
ophthalmic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080057483.9A
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English (en)
Chinese (zh)
Other versions
CN102811610A (zh
Inventor
B·梁
J·A·卡普里奥蒂
C·M·桑森
J·施泰因
M·魏泽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Foresight Biotherapeutics Inc
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Application filed by Foresight Biotherapeutics Inc filed Critical Foresight Biotherapeutics Inc
Priority to CN201510348236.9A priority Critical patent/CN104906580A/zh
Publication of CN102811610A publication Critical patent/CN102811610A/zh
Application granted granted Critical
Publication of CN102811610B publication Critical patent/CN102811610B/zh
Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201080057483.9A 2009-12-15 2010-12-15 无刺激性眼科聚维酮碘组合物 Expired - Fee Related CN102811610B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510348236.9A CN104906580A (zh) 2009-12-15 2010-12-15 无刺激性眼科聚维酮碘组合物

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28669709P 2009-12-15 2009-12-15
US61/286697 2009-12-15
US61/286,697 2009-12-15
PCT/US2010/060489 WO2011084473A1 (en) 2009-12-15 2010-12-15 Non-irritating ophthalmic povidone-iodine compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510348236.9A Division CN104906580A (zh) 2009-12-15 2010-12-15 无刺激性眼科聚维酮碘组合物

Publications (2)

Publication Number Publication Date
CN102811610A CN102811610A (zh) 2012-12-05
CN102811610B true CN102811610B (zh) 2016-05-18

Family

ID=44305700

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201510348236.9A Pending CN104906580A (zh) 2009-12-15 2010-12-15 无刺激性眼科聚维酮碘组合物
CN201080057483.9A Expired - Fee Related CN102811610B (zh) 2009-12-15 2010-12-15 无刺激性眼科聚维酮碘组合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201510348236.9A Pending CN104906580A (zh) 2009-12-15 2010-12-15 无刺激性眼科聚维酮碘组合物

Country Status (16)

Country Link
US (1) US20130177522A1 (es)
EP (1) EP2512230A4 (es)
JP (3) JP2013514373A (es)
KR (2) KR20120112537A (es)
CN (2) CN104906580A (es)
AR (1) AR079479A1 (es)
AU (1) AU2010339993A1 (es)
BR (1) BR112012014260A2 (es)
CA (1) CA2784492C (es)
CL (1) CL2012001583A1 (es)
EC (1) ECSP12012037A (es)
HK (1) HK1211216A1 (es)
MX (1) MX364441B (es)
PE (2) PE20160526A1 (es)
TW (3) TWI561239B (es)
WO (1) WO2011084473A1 (es)

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US7767217B2 (en) * 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
MX364441B (es) * 2009-12-15 2019-04-26 Foresight Biotherapeutics Inc Composiciones de povidona-yodo oftalmicas no irritantes.
CN103957922A (zh) * 2011-05-12 2014-07-30 前瞻生物治疗公司 含有甾体或非甾体抗炎药的稳定的聚维酮-碘组合物
GB201114725D0 (en) * 2011-08-25 2011-10-12 Altacor Ltd Ophthalmic formulations
TW201808311A (zh) * 2011-09-16 2018-03-16 遠景生物製藥股份有限公司 安定之普維酮-碘組成物
CN102429862B (zh) 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
JP6161500B2 (ja) * 2012-10-05 2017-07-12 ロート製薬株式会社 ブロムフェナク含有組成物
JP6304475B2 (ja) * 2013-01-31 2018-04-04 ロート製薬株式会社 点眼剤
JP6304474B2 (ja) * 2013-01-31 2018-04-04 ロート製薬株式会社 点眼剤
SI3517100T1 (sl) * 2013-02-01 2021-02-26 Allergan, Inc. Umetne solze, ki vsebujejo natrijev hialuronat in karboksimetilcelulozo
WO2014160579A1 (en) * 2013-03-25 2014-10-02 Insite Vision Incorporated Combination anti-inflammatory ophthalmic compositions
EP3013790A1 (en) 2013-06-27 2016-05-04 Mylan Laboratories Ltd. Process for the preparation of nepafenac
US20150064129A1 (en) * 2013-09-04 2015-03-05 Taiwan Biotech Co., Ltd. Wound healing composition
CN103877120B (zh) * 2014-04-02 2017-07-21 程予良 一种膏药
CN107847604B (zh) * 2015-10-25 2020-11-10 艾威药业(珠海)有限公司 眼用原位凝胶处方
JP6255134B1 (ja) * 2016-11-02 2017-12-27 ヴェローチェ・バイオファーマ・エルエルシー 耳炎の治療のための組成物および方法
CA3058097C (en) 2017-04-21 2024-01-02 Novaliq Gmbh Iodine compositions
CN108853074A (zh) * 2017-05-10 2018-11-23 武汉先路医药科技股份有限公司 一种含有溴芬酸钠水合物的药物水性滴眼液及其制备方法
WO2020061249A2 (en) * 2018-09-21 2020-03-26 Ps Therapies Ltd. Artificial tear, contact lens and drug vehicle compositions and methods of use thereof
CA3203779A1 (en) * 2021-01-21 2022-07-28 Joon Youb Lee Ophthalmic composition
US20230181625A1 (en) * 2021-12-14 2023-06-15 Harrow Ip, Llc Method and composition for treating infectious conjunctivitis
CN117338787A (zh) * 2023-11-24 2024-01-05 南京恒道医药科技股份有限公司 一种眼用药物组合物及其制备方法

Citations (6)

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US20080075790A1 (en) * 2006-09-21 2008-03-27 Alcon Manufacturing, Ltd. Self preserved aqueous pharmaceutical compositions
US20080132444A1 (en) * 2004-10-09 2008-06-05 Xiaoling Li Ocular Agent Delivery Systems
US20080172032A1 (en) * 2007-01-11 2008-07-17 James Pitzer Gills Method for preventing tissue damage associated with irrigation of tissue with an antimicrobial solution
CN101400355A (zh) * 2006-03-14 2009-04-01 Cls制药公司 包含聚维酮碘的眼用组合物
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
US20090314628A1 (en) * 2008-06-20 2009-12-24 Baxter International Inc. Methods for processing substrates comprising metallic nanoparticles

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MX364441B (es) * 2009-12-15 2019-04-26 Foresight Biotherapeutics Inc Composiciones de povidona-yodo oftalmicas no irritantes.
CN102429862B (zh) * 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080132444A1 (en) * 2004-10-09 2008-06-05 Xiaoling Li Ocular Agent Delivery Systems
CN101400355A (zh) * 2006-03-14 2009-04-01 Cls制药公司 包含聚维酮碘的眼用组合物
US20080075790A1 (en) * 2006-09-21 2008-03-27 Alcon Manufacturing, Ltd. Self preserved aqueous pharmaceutical compositions
US20080172032A1 (en) * 2007-01-11 2008-07-17 James Pitzer Gills Method for preventing tissue damage associated with irrigation of tissue with an antimicrobial solution
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
US20090314628A1 (en) * 2008-06-20 2009-12-24 Baxter International Inc. Methods for processing substrates comprising metallic nanoparticles

Also Published As

Publication number Publication date
CA2784492C (en) 2020-06-30
TWI618539B (zh) 2018-03-21
MX2012006881A (es) 2012-07-04
CA2784492A1 (en) 2011-07-14
TW201717973A (zh) 2017-06-01
EP2512230A1 (en) 2012-10-24
TWI620569B (zh) 2018-04-11
PE20121498A1 (es) 2012-11-30
TWI561239B (en) 2016-12-11
ECSP12012037A (es) 2012-08-31
TW201630614A (zh) 2016-09-01
CN104906580A (zh) 2015-09-16
BR112012014260A2 (pt) 2015-09-15
KR20120112537A (ko) 2012-10-11
MX364441B (es) 2019-04-26
CL2012001583A1 (es) 2013-01-11
PE20160526A1 (es) 2016-05-29
CN102811610A (zh) 2012-12-05
US20130177522A1 (en) 2013-07-11
NZ751915A (en) 2020-09-25
AU2010339993A1 (en) 2012-07-26
WO2011084473A1 (en) 2011-07-14
KR20190049931A (ko) 2019-05-09
AR079479A1 (es) 2012-01-25
HK1211216A1 (en) 2016-05-20
JP2016028101A (ja) 2016-02-25
EP2512230A4 (en) 2013-05-22
JP2018030871A (ja) 2018-03-01
JP2013514373A (ja) 2013-04-25
TW201143783A (en) 2011-12-16

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Effective date of registration: 20210106

Address after: Osaka City, Osaka Prefecture, Japan

Patentee after: TAKEDA PHARMACEUTICAL Co.,Ltd.

Address before: New York, USA

Patentee before: FORESIGHT BIOTHERAPEUTICS, Inc.

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Granted publication date: 20160518

Termination date: 20211215