CN102807511B - 一种从贻贝中提取牛磺酸的方法 - Google Patents
一种从贻贝中提取牛磺酸的方法 Download PDFInfo
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- CN102807511B CN102807511B CN 201210199181 CN201210199181A CN102807511B CN 102807511 B CN102807511 B CN 102807511B CN 201210199181 CN201210199181 CN 201210199181 CN 201210199181 A CN201210199181 A CN 201210199181A CN 102807511 B CN102807511 B CN 102807511B
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- CN
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- Prior art keywords
- taurine
- extracting
- elutriant
- solution
- distilled water
- Prior art date
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- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 title claims abstract description 174
- 229960003080 taurine Drugs 0.000 title claims abstract description 86
- 238000000034 method Methods 0.000 title claims abstract description 29
- 241000237536 Mytilus edulis Species 0.000 title claims abstract description 24
- 235000020638 mussel Nutrition 0.000 title claims abstract description 24
- 238000000605 extraction Methods 0.000 claims abstract description 26
- 238000001035 drying Methods 0.000 claims abstract description 13
- 238000002425 crystallisation Methods 0.000 claims abstract description 7
- 230000008025 crystallization Effects 0.000 claims abstract description 7
- 238000000926 separation method Methods 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 31
- 239000012153 distilled water Substances 0.000 claims description 26
- 239000012043 crude product Substances 0.000 claims description 25
- 238000000108 ultra-filtration Methods 0.000 claims description 22
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 20
- 239000013078 crystal Substances 0.000 claims description 16
- 238000001953 recrystallisation Methods 0.000 claims description 16
- 239000000706 filtrate Substances 0.000 claims description 14
- 235000013372 meat Nutrition 0.000 claims description 12
- 239000000126 substance Substances 0.000 claims description 12
- YCPXWRQRBFJBPZ-UHFFFAOYSA-N 5-sulfosalicylic acid Chemical compound OC(=O)C1=CC(S(O)(=O)=O)=CC=C1O YCPXWRQRBFJBPZ-UHFFFAOYSA-N 0.000 claims description 11
- 238000004809 thin layer chromatography Methods 0.000 claims description 11
- 239000011347 resin Substances 0.000 claims description 10
- 229920005989 resin Polymers 0.000 claims description 10
- 239000006228 supernatant Substances 0.000 claims description 10
- 239000012528 membrane Substances 0.000 claims description 9
- 238000010828 elution Methods 0.000 claims description 8
- 239000002253 acid Substances 0.000 claims description 7
- 125000002091 cationic group Chemical group 0.000 claims description 6
- 238000004587 chromatography analysis Methods 0.000 claims description 6
- 239000000047 product Substances 0.000 claims description 6
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 5
- 238000009835 boiling Methods 0.000 claims description 5
- 239000003729 cation exchange resin Substances 0.000 claims description 5
- 238000005119 centrifugation Methods 0.000 claims description 5
- 230000014759 maintenance of location Effects 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 238000002525 ultrasonication Methods 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 2
- 238000000265 homogenisation Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 7
- 238000003786 synthesis reaction Methods 0.000 description 5
- 239000012535 impurity Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 235000015170 shellfish Nutrition 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 238000009388 chemical precipitation Methods 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 238000013467 fragmentation Methods 0.000 description 2
- 238000006062 fragmentation reaction Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 206010004542 Bezoar Diseases 0.000 description 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
- 241000238424 Crustacea Species 0.000 description 1
- 241000237852 Mollusca Species 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- WBWWGRHZICKQGZ-UHFFFAOYSA-N Taurocholic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCCS(O)(=O)=O)C)C1(C)C(O)C2 WBWWGRHZICKQGZ-UHFFFAOYSA-N 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004641 brain development Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 229940094952 green tea extract Drugs 0.000 description 1
- 235000020688 green tea extract Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- WBWWGRHZICKQGZ-GIHLXUJPSA-N taurocholic acid Chemical compound C([C@@H]1C[C@H]2O)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)[C@H](O)C1 WBWWGRHZICKQGZ-GIHLXUJPSA-N 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 201210199181 CN102807511B (zh) | 2012-06-18 | 2012-06-18 | 一种从贻贝中提取牛磺酸的方法 |
Applications Claiming Priority (1)
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CN 201210199181 CN102807511B (zh) | 2012-06-18 | 2012-06-18 | 一种从贻贝中提取牛磺酸的方法 |
Publications (2)
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CN102807511A CN102807511A (zh) | 2012-12-05 |
CN102807511B true CN102807511B (zh) | 2013-12-25 |
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CN 201210199181 Active CN102807511B (zh) | 2012-06-18 | 2012-06-18 | 一种从贻贝中提取牛磺酸的方法 |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103342668B (zh) * | 2013-07-08 | 2016-06-01 | 集美大学 | 一种从鲍鱼内脏中提取天然牛磺酸的简易方法 |
WO2016153363A1 (en) * | 2015-03-24 | 2016-09-29 | The New Zealand Institute For Plant And Food Research Limited | Water-soluble mussel extract |
CN105949088B (zh) * | 2016-07-14 | 2018-09-14 | 大连民族大学 | 从虾中提取天然牛磺酸的方法 |
CN105949089B (zh) * | 2016-07-14 | 2018-09-14 | 大连民族大学 | 从贻贝中提取天然牛磺酸的方法 |
CN106986795B (zh) * | 2017-05-22 | 2018-08-24 | 南宁学院 | 一种从牛肝脏中提取牛磺酸的方法 |
CN107325027B (zh) * | 2017-06-19 | 2019-05-14 | 南宁学院 | 一种从牛心中提取牛磺酸的方法 |
CN113200889A (zh) * | 2020-12-18 | 2021-08-03 | 浙江经贸职业技术学院 | 用贻贝制备牛磺酸的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1137267C (zh) * | 2001-03-20 | 2004-02-04 | 石子聪 | 天然牛磺酸生产方法 |
JP3819000B2 (ja) * | 2003-12-17 | 2006-09-06 | 日本クリニック株式会社 | タウリンの抽出方法 |
CN100339364C (zh) * | 2006-01-18 | 2007-09-26 | 厦门东海洋水产品进出口有限公司 | 利用膜分离技术从章鱼下脚料中提取天然牛磺酸的方法 |
CN102477004A (zh) * | 2010-11-22 | 2012-05-30 | 河北农业大学 | 一种利用超滤技术从牡蛎中提取天然牛磺酸的方法 |
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Application publication date: 20121205 Assignee: ZHOUSHAN JUNYAO TECHNOLOGY DEVELOPMENT Co.,Ltd. Assignor: ZHEJIANG MARINE DEVELOPMENT Research Institute Contract record no.: X2022330000116 Denomination of invention: A method for extracting taurine from mussels Granted publication date: 20131225 License type: Common License Record date: 20220525 |
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Application publication date: 20121205 Assignee: ZHOUSHAN NATIONAL OCEANIC FISHERY BASE TECHNOLOGY DEVELOPMENT Co.,Ltd. Assignor: ZHEJIANG MARINE DEVELOPMENT Research Institute Contract record no.: X2022330000185 Denomination of invention: A method for extracting taurine from mussels Granted publication date: 20131225 License type: Common License Record date: 20220609 |
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Application publication date: 20121205 Assignee: SHENGSI COUNTY GUANDAO AQUATIC PRODUCTS Co.,Ltd. Assignor: ZHEJIANG MARINE DEVELOPMENT Research Institute Contract record no.: X2022330000404 Denomination of invention: A method of extracting taurine from mussels Granted publication date: 20131225 License type: Common License Record date: 20220811 |
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Application publication date: 20121205 Assignee: ZHOUSHAN HAILISHENG MARINE ORGANISM RESEARCH INSTITUTE CO.,LTD. Assignor: ZHEJIANG MARINE DEVELOPMENT Research Institute Contract record no.: X2023980044131 Denomination of invention: A Method for Extracting Taurine from Mussels Granted publication date: 20131225 License type: Common License Record date: 20231023 |