CN102798623A - Double-signal lung cancer exhaled air detection method - Google Patents
Double-signal lung cancer exhaled air detection method Download PDFInfo
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- CN102798623A CN102798623A CN2012103318854A CN201210331885A CN102798623A CN 102798623 A CN102798623 A CN 102798623A CN 2012103318854 A CN2012103318854 A CN 2012103318854A CN 201210331885 A CN201210331885 A CN 201210331885A CN 102798623 A CN102798623 A CN 102798623A
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Abstract
The invention discloses a double-signal lung cancer exhaled air detection method which comprises the following steps of: A, arranging a porphyrin sensor film into an air reaction chamber; B, applying a plurality of excitation light sources to exciting a porphyrin sensor before reaction, and sending detected spectral data into an ARM (Advanced RISC Machines) chip; C, sending image data before reaction, which is detected, by a camera into the ARM chip; D, sending lung cancer exhaled air to be detected into the air reaction chamber, and carrying out reaction on the lung cancer exhaled air and the porphyrin sensor; E, sending image data detected by a camera into the ARM chip; F, applying the plurality of excitation light sources to exciting the porphyrin sensor after reaction, and sending detected spectral data into the ARM chip; and G, carrying out analysis treatment by the ARM chip. According to the double-signal lung cancer exhaled air detection method disclosed by the invention, a fluorescence spectrum signal and a visible light color signal are adopted to carry out simultaneous measurement and carry out detection through crossing response, so that detection is rapid, the sensitivity is high, the accuracy of detection is greatly improved, the cost is low, and the operation is simple.
Description
Technical field
The present invention relates to a kind of lung cancer breath detection method, relate in particular to a kind of dual signal lung cancer breath detection method.
Background technology
Lung cancer is one of modal malignant tumour in the world at present.Since nearly 30 years, although people are greatly improved to the diagnosis and the treatment of lung cancer, lung cancer is still the disease of serious threat health of people and life.
Traditional lung cancer detection method mainly contains: use large-scale instrument 1.: X sheet, CT, PET etc., cost an arm and a leg, and the ordinary people is difficult to accept; 2. phlegm inspection: accuracy rate is very low; 3. biopsy: wound is arranged, generally be that large-scale instrument such as CT detects and just considers after doubtful; 4. conventional breath detects: clinically also do not see application,, needs to use gas chromatography (GC), gas-technology such as matter coupling also in the experimental phase, and complicated operation, consuming time longer, equipment is also very expensive, and error is bigger.
Summary of the invention
To weak point of the prior art, the object of the present invention is to provide a kind of low price, simple to operate, detection is fast, and is highly sensitive, can effectively improve the dual signal lung cancer breath detection method of accuracy in detection.
In order to solve the problems of the technologies described above, the present invention has adopted following technical scheme:
Dual signal lung cancer breath detection method; Adopted a kind of dual signal lung cancer breath detection system in the method, this dual signal lung cancer breath detection system comprises fluorescence detection device, visible light pick-up unit, gas reaction device, spectrometer and ARM chip;
Said fluorescence detection device comprises fibre-optical probe, motor I, excitation source transfer table, optical filter installing plate and turning axle I; Said turning axle I pass excitation source transfer table and optical filter installing plate and with excitation source transfer table and optical filter installing plate secure fit, the turning axle I is driven by the motor I and rotates; Said excitation source transfer table is provided with the excitation source of at least three and different wave lengths equidistant with the turning axle I; On the optical filter installing plate, be provided with the optical filter that equates with excitation source quantity, the excitation source on the optical filter on the said optical filter installing plate and the excitation source transfer table the turning axle I axially on corresponding one by one; The rotational trajectory of the optical filter on said fibre-optical probe and the optical filter installing plate is corresponding, and fibre-optical probe is connected with spectrometer through optical fiber;
Said visible light pick-up unit comprises led light source plate and camera; One side of said led light source plate is provided with a semicircle orifice, and said led light source plate is provided with a plurality of and the equidistant LED lamp of semicircle orifice, said camera be positioned at the LED light source board directly over;
Said gas reaction device comprises motor II, gas reaction chamber, reaction bench and turning axle II; It is indoor that said reaction bench is positioned at gas reaction, and the turning axle II passes the bottom of gas reaction chamber and with its rotation and be sealed and matched, said reaction bench is fixed on the end of turning axle II, and the turning axle II is driven by the motor II; The bottom of said gas reaction chamber and the top cover of gas reaction chamber are processed by transparent material;
Said gas reaction chamber is between fluorescence detection device and visible light pick-up unit, and the position height of gas reaction chamber is higher than led light source plate and excitation source transfer table, and the position height of said gas reaction chamber is lower than camera and optical filter installing plate.
This dual signal lung cancer breath detection method comprises the steps:
A, porphyrin sensor slice, thin piece is put on the indoor reaction bench of gas reaction, porphyrin sensor slice, thin piece upper edge circumferencial direction is laid with several porphyrin sensors;
B, gas reaction chamber is moved to fluorescence detection device; Open excitation source; Excitation source uses a plurality of excitation sources that the porphyrin sensor on the porphyrin sensor slice, thin piece before reacting is excited under the drive of motor I, and the preceding spectroscopic data of reaction that uses spectrometer to record is sent into the ARM chip;
C, gas reaction chamber is moved to the visible light pick-up unit, turn on the LED lamp on the led light source plate, and the view data of opening before the reaction that camera will record is sent into the ARM chip; The motor II drives reaction bench and porphyrin sensor slice, thin piece Rotate 180 degree, and the preceding view data of reaction of using camera to record is sent into the ARM chip, closes the LED lamp;
D, the lung cancer breath to be detected that will collect are sent into gas reaction chamber; Drive reaction bench through the motor II and rotated several minutes, make lung cancer breath to be detected be uniformly distributed in the gas reaction chamber and fully react with porphyrin sensor on the porphyrin sensor slice, thin piece with porphyrin sensor slice, thin piece;
E, turn on the LED lamp on the led light source plate, and open the reacted view data that camera will record and send into the ARM chip; The motor II drives reaction bench and porphyrin sensor slice, thin piece Rotate 180 degree, and the reacted view data of using camera to record is sent into the ARM chip, closes the LED lamp;
F, gas reaction chamber is moved to fluorescence detection device; Open excitation source; Excitation source excites the porphyrin sensor on the reacted porphyrin sensor slice, thin piece at a plurality of excitation sources of utilization under the drive of motor I, and the reacted spectroscopic data that uses spectrometer to record is sent into the ARM chip;
G, close all light sources, the ARM chip carries out analyzing and processing to fluorescence and visible light dual signal, and provides testing result.
Compared with prior art, dual signal lung cancer breath detection method of the present invention has following advantage:
1, the present invention adopts fluorescence spectrum and two kinds of signals of visible light colors to measure simultaneously, detects through cross response, detects fast, and is highly sensitive, improved the accuracy that detects greatly, and low price, simple to operate.
2, adopt the motor-driven reaction bench to rotate in this gas detection method; Lung cancer breath to be measured is evenly distributed in gas reaction chamber, and the reaction chamber that need not complex design as other some gas-detecting devices come the flow velocity, advection of pilot-gas etc. and then gas can be evenly distributed in the reaction chamber.
3, the porphyrin sensor on the porphyrin sensor slice, thin piece is the multiple porphyrin that designs to lung cancer exhalation gas marker specially, can anti-change of giving birth to corresponding fluorescence and visible light after these porphyrins and the reaction of lung cancer symbolic gas.Use different sensitive materials to can be used for detecting different gas on the porphyrin sensor slice, thin piece; Be not limited to the lung cancer breath; Also can be that other escaping gas of industry, Environmental securities etc. such as ammonia, sulphuric dioxide, formaldehyde detects, system's detected gas concentration can reach the ppb level.
Description of drawings
Fig. 1 is the structural representation of dual signal lung cancer breath detection system;
Fig. 2 is the structural representation of shell;
Fig. 3 is the structural representation of excitation source brace table;
Fig. 4 is the structural representation of motor I;
Fig. 5 is the structural representation of excitation source coupling shaft;
Fig. 6 is the structural representation that excitation source transfer table, optical filter installing plate and turning axle I cooperate;
Fig. 7 is the structural representation of excitation source;
Fig. 8 is the structural representation of led light source plate;
Fig. 9 is the structural representation that reaction bench and turning axle II cooperate;
Figure 10 is the structural representation of porphyrin sensor slice, thin piece;
Figure 11 is the structural representation of gas reaction chamber;
Figure 12 is the structural representation of gas reaction chamber top cover;
Figure 13 is the structural representation that base, guide pole and screw mandrel cooperate;
Figure 14 is the structural representation of sliding table.
In the accompanying drawing: 1-fibre-optical probe; 2-excitation source brace table; 3-motor I; 4-excitation source; 5-excitation source transfer table; 6-optical filter installing plate; 7-turning axle I; 8-optical filter; 9-spectrometer; 10-led light source plate; 11-camera; 12-semicircle orifice; 13-LED lamp; 14-motor II; 15-gas reaction chamber; 16-reaction bench; 17-turning axle II; 18-porphyrin sensor slice, thin piece; 19-air pump; 20-porphyrin sensor; 21-top cover; 22-air intake opening; 23-gas outlet; 24-motor III; 25-base; 26-slide block; 27-nut block; 28-guide pole; 29-screw mandrel; 30-sliding table; 31-laser diode; 32-photoelectric tube; 33-magnetic patch; 34-shell; 35-liquid crystal display; 36-removable cover; 37-fibre-optical probe installing plate; 38-motor mounting plate; 39-web joint; 40-planetary reduction gear; 41-excitation source coupling shaft; 42-PTO; 43-dowel hole; 44-round platform; 45-planetary reduction gear; 46-shaft coupling; 47-slice, thin piece register pin; 48-pilot hole; 49-planetary reduction gear; 50-shaft coupling; 51-back up pad; 52-spectrometer fixed station.
Embodiment
Below in conjunction with accompanying drawing and embodiment the present invention is done to describe in further detail.
As shown in Figure 1; Dual signal lung cancer breath detection method; Adopted a kind of dual signal lung cancer breath detection system in the method, this dual signal lung cancer breath detection system comprises fluorescence detection device, visible light pick-up unit, gas reaction device, spectrometer 9, ARM chip and shell 34.The structure of shell 34 is as shown in Figure 2, and fluorescence detection device, visible light pick-up unit, gas reaction device and ARM chip are installed in the shell 34, and spectrometer 9 is fixed on the inwall of shell 34 through spectrometer fixed station 52.Be equipped with on the front plate of shell 34 and be used to the liquid crystal display 35 that touches, control and show, be provided with a cavity at the top of shell 34, be provided with in the cavity one change porphyrin sensor slice, thin piece 18 removable cover 36 (can accomplish change blade technolgy through this removable cover 36).Liquid crystal display 35 is used for man-machine interaction, is connected with the ARM chip, if use USB that system is connected with computing machine, then liquid crystal display 35 will be closed automatically, and relevant data analysis also will be carried out analyzing and processing by the software of installing on computers.
Wherein, fluorescence detection device comprises fibre-optical probe 1, excitation source brace table 2, motor I 3, excitation source transfer table 5, optical filter installing plate 6, turning axle I 7 and excitation source coupling shaft 41.The structure of excitation source brace table 2 is as shown in Figure 3; The top of excitation source brace table 2 is a fibre-optical probe installing plate 37; The bottom of excitation source brace table 2 is a motor mounting plate 38; Have a plate 39 at the back side of excitation source brace table 2, the bolt hole through this web joint 39 is fixedly connected on this excitation source brace table 2 on the inwall of shell 34.Motor I 3 adopts stepper motor, and as shown in Figure 4, this stepper motor has planetary reduction gear 40, and motor I 3 is installed on the motor mounting plate 38, and the PTO 42 of planetary reduction gear 40 upwards.Excitation source coupling shaft 41 is a hollow structure; As shown in Figure 5; The bottom of excitation source coupling shaft 41 is enclosed within on the PTO 42 of planetary reduction gear 40; Turning axle I 7 pass excitation source transfer table 5 and optical filter installing plate 6 and with excitation source transfer table 5 and optical filter installing plate 6 secure fit; Insert in the top-portion apertures of excitation source coupling shaft 41 bottom of turning axle I 7, and through inserting the locking positioning pin in the dowel hole 43 that on excitation source coupling shaft 41, is provided with and turning axle I 7 being fixed on the excitation source coupling shaft 41, turning axle I 7 is driven by motor I 3 and rotates.The structure of excitation source transfer table 5 and optical filter installing plate 6 is as shown in Figure 6; In the cavity that excitation source transfer table 5 and optical filter installing plate 6 all form between fibre-optical probe installing plate 37 and motor mounting plate 38, fibre-optical probe installing plate 37 is parallel to each other with motor mounting plate 38.Excitation source transfer table 5 is provided with the excitation source 4 of at least three and different wave lengths equidistant with turning axle I 7 (in the present embodiment; On excitation source transfer table 5, be provided with three excitation sources 4); The structure of excitation source is as shown in Figure 7, and all excitation sources 4 all are positioned on the semi-circumference on the excitation source transfer table 5.On optical filter installing plate 6, be provided with the optical filter 8 that equates with excitation source 4 quantity (in the present embodiment; On optical filter installing plate 6, be provided with three optical filters 8); All optical filters 8 all are positioned on the semi-circumference on the optical filter installing plate 6, the excitation source 4 on the optical filter 8 on the optical filter installing plate 6 and the excitation source transfer table 5 turning axle I 7 axially on corresponding one by one.On fibre-optical probe installing plate 37, be provided with the round platform 44 that is threaded the hole, fibre-optical probe 1 is installed on the round platform 44 and is corresponding with the rotational trajectory in the vertical direction of optical filter 8 on the optical filter installing plate 6, and fibre-optical probe 1 is connected with spectrometer 9 through optical fiber.Will be through fibre-optical probe 1 through the fluorescence spectrum signal input spectrum appearance 9 of filter plate 8, spectrometer 9 is sent the spectroscopic data that records into the ARM chip.
The visible light pick-up unit comprises led light source plate 10 and camera 11.The structure of led light source plate is as shown in Figure 8; One side of led light source plate 10 is provided with a semicircle orifice 12; Led light source plate 10 is provided with a plurality of and semicircle orifice 12 equidistant LED lamps 13; Camera 11 be positioned at LED light source board 10 directly over, camera 11 is connected with the ARM chip, camera 11 is sent visible light colors signal (being view data) into the ARM chip.
Gas reaction device comprises the driving mechanism that motor II 14, gas reaction chamber 15, reaction bench 16, turning axle II 17, porphyrin sensor slice, thin piece 18, air pump 19 and drive motor II 14 move horizontally.Reaction bench 16 is positioned at gas reaction chamber 15; Turning axle II 17 is passed the bottom of gas reaction chamber 15 and the bottom through sealing bearing and gas reaction chamber 15 and is rotated and be sealed and matched; Reaction bench 16 is fixed on the end of turning axle II 17, and reaction bench 16 is as shown in Figure 9 with the structure that turning axle II 17 is connected.Motor II 14 adopts stepper motor, and this stepper motor has planetary reduction gear 45, and the bottom of turning axle II 17 is connected with the PTO of planetary reduction gear 45 through shaft coupling 46, and turning axle II 17 is driven by motor II 14.On the upper surface of reaction bench 16, be provided with three slice, thin piece register pins 47; The structure of porphyrin sensor slice, thin piece 18 is shown in figure 10; On porphyrin sensor slice, thin piece 18, be provided with the pilot hole 48 that is used with three slice, thin piece register pins 47; This porphyrin sensor slice, thin piece 18 is placed on the reaction bench 16; Three slice, thin piece register pins 47 insert respectively in the corresponding pilot hole 48, and then make porphyrin sensor slice, thin piece 18 dismountable being arranged on the reaction bench 16, are laid with several and turning axle II 17 equidistant porphyrin sensors 20 on the porphyrin sensor slice, thin piece 18.The bottom of gas reaction chamber 15 and the top cover of gas reaction chamber 21 are processed by transparent material; The structure of gas reaction chamber 15 is shown in figure 11; The structure of top cover 21 is shown in figure 12, on the sidewall of gas reaction chamber 15, is provided with air intake opening 22 and gas outlet 23, and air pump 19 is connected with air intake opening 22.In this gas reaction chamber 15, feed the lung cancer breath; Step motor drive gas reaction chamber 15 rotates; Lung cancer breath to be measured is evenly distributed in gas reaction chamber 15, and this gas reaction device can make lung cancer breath and porphyrin sensor 20 react.
Driving mechanism comprises motor III 24 (employing stepper motor), planetary reduction gear 49, shaft coupling 50, base 25, slide block 26, nut block 27, guide pole 28 (in the present embodiment, guide pole 28 is two), screw mandrel 29 and sliding table 30.The two ends of two guide poles 28 are fixed on the back up pad 51 that the two ends of base 25 are provided with; On the back up pad 51 that the two ends of screw mandrel 29 are provided with through the rotating two ends that are arranged on base 25 of bearing; Screw mandrel 29 is between two guide poles 28; Guide pole 28 is parallel with screw mandrel 29, and is shown in figure 13, and motor III 24 drives screw mandrel 29 through planetary reduction gear 49 and shaft coupling 50 and rotates.Slide block 26 and nut block 27 are fixed on the below of sliding table 30; Motor II 14 is installed on the sliding table 30; Slide block 26 all is slidingly matched with base 25 with nut block 27; All be with slide block 26 on two guide poles 28, slide block 26 is slidingly matched with guide pole 28, nut block 27 rotation sets on screw mandrel 29 and with screw mandrel 29 threaded engagement.On a side of base 25, be provided with three laser diodes 31, the side of sliding table 30 is provided with photoelectric tube 32 (shown in figure 14), and photoelectric tube 32 can be corresponding successively with three laser diodes 31 in sliding table 30 moving process.Two laser diode 31 in the vertical directions near two ends on fluorescence detection device and visible light pick-up unit and the base 25 are corresponding one by one.
On the top circumference of gas reaction chamber 15, be provided with four grooves; Magnet is installed in the groove; On the top cover 21 of gas reaction chamber 15, be provided with four with groove in the magnet 33 inhaled mutually of the magnet installed, the magnet 33 of the top cover 21 of gas reaction chamber 15 through mutual absorption is adsorbed on the gas reaction chamber 15 and through encapsulant and cooperates with the top seal of gas reaction chamber 15.
The ARM chip is connected with spectrometer 9, camera 11 and PIC single-chip microcomputer (adopting PIC16F877A) respectively, and motor I 3, motor II 14, motor III 24, air pump 19, excitation source 4, LED lamp 13 and laser diode 31 are by the PIC Single-chip Controlling.ARM chip and PIC single-chip microcomputer are installed on the circuit board, and circuit board is installed in the shell 34, and the ARM chip uses serial ports communication with it as the host computer of PIC single-chip microcomputer.Embedded system ARM adopts ARM9 chip S3C2440, also can adopt other embedded system chips.System reserves 2 USB interfaces, and one of which is used for ARM result and related data are copied out, another can be used for and computing machine between communication.
This dual signal lung cancer breath detection method comprises the steps:
A, startup self-detection are put into porphyrin sensor slice, thin piece 18 on the reaction bench 16 of gas reaction chamber 15 through removable cover 36
B, motor III 24 drive screw mandrels 29 drive sliding tables 30 and on parts move to the fluorescence detection device (fluoroscopic examination station) on right side from initial station (middle laser diode position); Open excitation source 4; Excitation source 4 uses each the porphyrin sensor 20 on the porphyrin sensor slice, thin piece 18 before 4 pairs of reactions of a plurality of excitation sources to excite under the drive of motor I 3, and the preceding spectroscopic data of reaction that uses spectrometer 9 to record is sent into the ARM chip;
C, motor III 24 drive screw mandrels 29 drive sliding tables 30 and on parts move to the visible light pick-up unit (visible light detection station) in left side from the fluoroscopic examination station; Automatically turn on the LED lamp 13 on the led light source plate 10, and the view data of opening before the reaction that camera 11 will record is sent into the ARM chip; Motor II 14 drives reaction bench 16 and porphyrin sensor slice, thin piece 18 Rotate 180 degree, and the preceding view data of reaction of using camera 11 to record is sent into the ARM chip, closes the LED lamp;
D, will collect and standardized lung cancer breath to be detected send into gas reaction chamber 15 through air pump 19; Drive reaction bench 16 and porphyrin sensor slice, thin piece 18 rotations several minutes through motor II 14, make lung cancer breath to be detected be uniformly distributed in the gas reaction chamber 15 and with porphyrin sensor slice, thin piece 18 on fully reaction of sensitive spot (being porphyrin sensor 20);
E, turn on the LED lamp 13 on the led light source plate 10, and open the reacted view data that camera 11 will record and send into the ARM chip; Motor II 14 drives reaction bench 16 and porphyrin sensor slice, thin piece 18 Rotate 180 degree, and the reacted view data of using camera 11 to record is sent into the ARM chip, closes LED lamp 13;
F, motor III 24 drive screw mandrels 29 drive sliding tables 30 and on parts detect station from visible light and move to the fluoroscopic examination station; Open excitation source 4; Excitation source 4 excites the sensitive spot on the reacted porphyrin sensor slice, thin piece 18 (being porphyrin sensor 20) at a plurality of light sources of utilization under the drive of motor I 3, and the reacted data of using spectrometer 9 to record are sent into the ARM chip;
G, close all light sources; Air pump 19 logical whole gas reaction chamber 15 of nitrogen purge and gas circuits reclaim waste gas; Motor III 24 drive screw mandrels 29 drive sliding tables 30 and on parts get back to initial station; The ARM chip carries out analyzing and processing to fluorescence and visible light dual signal, and provides testing result.
Explanation is at last; Above embodiment is only unrestricted in order to technical scheme of the present invention to be described; Although with reference to preferred embodiment the present invention is specified, those of ordinary skill in the art should be appreciated that and can make amendment or be equal to replacement technical scheme of the present invention; And not breaking away from the aim and the scope of present technique scheme, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (1)
1. dual signal lung cancer breath detection method; It is characterized in that: adopted a kind of dual signal lung cancer breath detection system in the method, this dual signal lung cancer breath detection system comprises fluorescence detection device, visible light pick-up unit, gas reaction device, spectrometer (9) and ARM chip;
Said fluorescence detection device comprises fibre-optical probe (1), motor I (3), excitation source transfer table (5), optical filter installing plate (6) and turning axle I (7); Said turning axle I (7) pass excitation source transfer table (5) and optical filter installing plate (6) and with excitation source transfer table (5) and optical filter installing plate (6) secure fit, turning axle I (7) is driven by motor I (3) and rotates; Said excitation source transfer table (5) is provided with the excitation source (4) of at least three and different wave lengths equidistant with turning axle I (7); On optical filter installing plate (6), be provided with the optical filter (8) that equates with excitation source (4) quantity, the excitation source (4) on the optical filter (8) on the said optical filter installing plate (6) and the excitation source transfer table (5) turning axle I (7) axially on corresponding one by one; The rotational trajectory of the optical filter (8) on said fibre-optical probe (1) and the optical filter installing plate (6) is corresponding, and fibre-optical probe (1) is connected with spectrometer (9) through optical fiber;
Said visible light pick-up unit comprises led light source plate (10) and camera (11); One side of said led light source plate (10) is provided with a semicircle orifice (12), and said led light source plate (10) is provided with a plurality of and the equidistant LED lamp of semicircle orifice (12) (13), said camera (11) be positioned at LED light source board (10) directly over;
Said gas reaction device comprises motor II (14), gas reaction chamber (15), reaction bench (16) and turning axle II (17); Said reaction bench (16) is positioned at gas reaction chamber (15); Turning axle II (17) is passed the bottom of gas reaction chamber (15) and with its rotation and be sealed and matched; Said reaction bench (16) is fixed on the end of turning axle II (17), and turning axle II (17) is driven by motor II (14); The top cover (21) of the bottom of said gas reaction chamber (15) and gas reaction chamber is processed by transparent material;
Said gas reaction chamber (15) is between fluorescence detection device and visible light pick-up unit; The position height of gas reaction chamber (15) is higher than led light source plate (10) and excitation source transfer table (5), and the position height of said gas reaction chamber (15) is lower than camera (11) and optical filter installing plate (6);
This dual signal lung cancer breath detection method comprises the steps:
A, porphyrin sensor slice, thin piece (18) is put on the reaction bench (16) of gas reaction chamber (15), along the circumferential direction be laid with several porphyrin sensors (20) on the porphyrin sensor slice, thin piece (18);
B, gas reaction chamber (15) is moved to fluorescence detection device; Open excitation source (4); Excitation source (4) uses a plurality of excitation sources (4) that the porphyrin sensor (20) on the porphyrin sensor slice, thin piece (18) before reacting is excited under the drive of motor I (3), and the preceding spectroscopic data of reaction that uses spectrometer (9) to record is sent into the ARM chip;
C, gas reaction chamber (15) is moved to the visible light pick-up unit, turn on the LED lamp (13) on the led light source plate (10), and the view data of opening before the reaction that camera (11) will record is sent into the ARM chip; Motor II (14) drives reaction bench (16) and porphyrin sensor slice, thin piece (18) Rotate 180 degree, and the preceding view data of reaction of using camera (11) to record is sent into the ARM chip, closes the LED lamp;
D, the lung cancer breath to be detected that will collect are sent into gas reaction chamber (15); Drive reaction bench (16) and porphyrin sensor slice, thin piece (18) rotation several minutes through motor II (14), make lung cancer breath to be detected be uniformly distributed in the gas reaction chamber (15) and fully react with porphyrin sensor (20) on the porphyrin sensor slice, thin piece (18);
E, turn on the LED lamp (13) on the led light source plate (10), and open the reacted view data that camera (11) will record and send into the ARM chip; Motor II (14) drives reaction bench (16) and porphyrin sensor slice, thin piece (18) Rotate 180 degree, and the reacted view data of using camera (11) to record is sent into the ARM chip, closes LED lamp (13);
F, gas reaction chamber (15) is moved to fluorescence detection device; Open excitation source (4); Excitation source (4) excites the porphyrin sensor (20) on the reacted porphyrin sensor slice, thin piece (18) at a plurality of excitation sources of utilization (4) under the drive of motor I (3), and the reacted spectroscopic data that uses spectrometer (9) to record is sent into the ARM chip;
G, close all light sources, the ARM chip carries out analyzing and processing to fluorescence and visible light dual signal, and provides testing result.
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