CN203981588U - A kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle - Google Patents
A kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle Download PDFInfo
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- CN203981588U CN203981588U CN201420409350.9U CN201420409350U CN203981588U CN 203981588 U CN203981588 U CN 203981588U CN 201420409350 U CN201420409350 U CN 201420409350U CN 203981588 U CN203981588 U CN 203981588U
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- 238000001917 fluorescence detection Methods 0.000 title claims abstract description 22
- 238000012360 testing method Methods 0.000 claims abstract description 52
- 230000005284 excitation Effects 0.000 claims abstract description 45
- 230000003287 optical effect Effects 0.000 claims abstract description 38
- 238000001514 detection method Methods 0.000 claims description 20
- 230000007246 mechanism Effects 0.000 claims description 11
- 230000003993 interaction Effects 0.000 claims description 8
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 7
- 230000005540 biological transmission Effects 0.000 claims description 6
- 230000003321 amplification Effects 0.000 claims description 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 abstract description 17
- 230000007613 environmental effect Effects 0.000 abstract description 14
- 230000008901 benefit Effects 0.000 abstract description 4
- 239000000758 substrate Substances 0.000 abstract description 4
- 239000000463 material Substances 0.000 description 11
- 230000008569 process Effects 0.000 description 9
- 230000002452 interceptive effect Effects 0.000 description 7
- 239000012535 impurity Substances 0.000 description 5
- 239000003550 marker Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000003317 immunochromatography Methods 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 238000004043 dyeing Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012921 fluorescence analysis Methods 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 239000007844 bleaching agent Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model relates to a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle, by control circuit is set in housing, test strips is inserted from the test strips insert port of housing, the fluorescence intensity that control circuit control optical detecting module is treated survey subject matter detects, scanning sample, by control circuit, fluorescence intensity is analyzed, obtain the concentration of subject matter, wherein be located at photoelectric sensor both sides excitation source entrance port relative closure and be symmetrical arranged centered by the axis of the entrance port of photoelectric sensor, the interference that ensures fluoroscopic examination is as far as possible little, and fluorescence excitation intensity is larger.The fluorescence that the utility model not only can be eliminated substrate in sample equally disturbs, can also eliminate the signal such as environmental background light, space electromagnetic wave power frequency interference, promote and detect fluorescent measure signal intensity, possess the advantage that conventional fluorescence detection method cannot complete, the fluorescence intensity that can be applicable to the field subject matters such as biology, chemistry, medical science detects.
Description
Technical field
The utility model belongs to by means of measuring the chemistry of material or physical property is tested or the technical field of analysis of material, and particularly a kind of fluorescence that can eliminate substrate in sample disturbs, eliminates environmental background light, eliminates the fluorescence detection device based on mutually balanced multiple-frequency modulation principle that the signals such as space electromagnetic wave power frequency interference detect fluorescent measure signal intensity to promote, improve fluoroscopic examination precision.
Background technology
The specific operation process of fluorescence analysis is: in test strips, carry out fluorchrome dyeing and process; Test strips is put into detection sample, in the time detecting the detection subject matter that contains energy and fluorchrome combination in sample, can carry out fluorchrome dyeing to the measurement subject matter of sample; Then utilize exciting light to irradiate sample, fluorescence excitation pigment sends fluorescence, is analyzed the information such as kind, concentration of measuring subject matter by the intensity level of final fluorescence.This technical requirement is carried out correct analysis according to fluorescence information to measuring subject matter at short notice.
At present, immunochromatography (lateral flow immunoassay, LFIA) Rapid detection test strip is more conventional in fluorescence analysis field, and the field of immunochromatography fluoroscopic examination in recent years makes a breakthrough technically, have that highly sensitive, high specificity, fluorescence lifetime are long, the feature such as good stability and no radioactivity pollute, can be widely used in situ quantitation and detect, be the important directions of following instant detection technique development.
But, exciting light irradiates and inspires in the process of fluorescence, except measuring the fluorescence of subject matter transmitting, that is to say outside the fluorescence information that is marked at the fluorchrome on sample, also comprise two large classes interference fluorescence, disturb fluorescence to comprise environmental background fluorescence and impurity fluorescence excitation.So-called environmental background fluorescence, includes the wider fluorescence of the wave band of autofluorescence, reflection of liquid at the bottom of sample or test strips itself, light leak and the electromagnetic interference (EMI) etc. of detection system; Impurity fluorescence excitation is mainly due to the material that comprises non-measurement subject matter in sample, and the optical excitation that also may be excited of this class material goes out fluorescence, just this class fluorescence excite different with measurement subject matter fluorescence process with cancellation process.When above-mentioned these disturb the fluorescence wave band overlaid that fluorescence wave bands and fluorchrome send, if the fluorescence phase specific strength of disturbing fluorescence and fluorchrome to send is extremely faint, utilize general fluorescence detection method detection fluorescent intensity just can measure the concentration information of subject matter, when but the undercapacity of the fluorescence sending when fluorchrome is enough strong, can produce larger error, have a strong impact on the result of Measurement and analysis.
In general fluoroscopic examination, exciting light irradiates sample excitation fluorescent emission, by optical filter filtering reflected light and impurity fluorescence, only detects the fluorescent intensity of subject matter emitting fluorescence wavelength coverage to be measured, thereby obtains the relatively accurate information of subject matter of measuring.Although this kind detects the impact that can eliminate interfering material fluorescence excitation, but because interfering material has uncertainty, environmental background disturbs also has uncertainty, therefore can not affirm and eliminate all interfering material fluorescence excitations completely, and said method can not be eliminated the environmental background light interference that same fluorchrome wave band overlaps completely, also has the problems such as detection system light leak and electromagnetic interference (EMI).
Utility model content
The technical matters that the utility model solves is, in prior art, exciting light irradiates and inspires in the process of fluorescence, except measuring the fluorescence of subject matter transmitting, that is to say outside the fluorescence information that is marked at the fluorchrome on sample, also comprise the large class interference of environmental background fluorescence and impurity fluorescence excitation two fluorescence, and cause because interfering material has uncertainty, environmental background disturbs also has uncertainty, therefore can not affirm and eliminate all interfering material fluorescence excitations completely, and most methods can not be eliminated the environmental background light interference that same fluorchrome wave band overlaps completely, also has the problem of detection system light leak and electromagnetic interference (EMI) etc., and then provide a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle of optimizing structure.
The technical scheme that the utility model adopts is, a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle, comprise housing, described housing sidepiece is provided with test strips insert port, in described housing, be provided with optical de-tection means and control circuit, described optical de-tection means is connected with control circuit, described optical de-tection means also comprises the test strips mounting table being equipped with described test strips insert port and is located in turn guiding mechanism and the optical detecting module of test strips mounting table top, and described optical detecting module is connected with stepper motor by screw pair; Described optical detecting module comprises detection pedestal, and described detection pedestal is provided with photoelectric sensor and is located at the excitation source entrance port of photoelectric sensor both sides, and described excitation source entrance port is symmetrical arranged centered by the axis of the entrance port of photoelectric sensor; Described stepper motor, photoelectric sensor are connected with described control circuit.
Preferably, described photoelectric sensor is perpendicular to described test strips mounting table, and the axis of the axis of the entrance port of described photoelectric sensor and 2 excitation source entrance ports is intersected on test strips mounting table.
Preferably, described photoelectric sensor is photodiode.
Preferably, described excitation source is light emitting diode.
Preferably, described excitation source entrance port place is provided with inserted slot.
Preferably, described guiding mechanism is guide rail, and the guide direction of described guide rail is consistent with the guide direction of test strips mounting table.
Preferably, described control circuit comprises fluoroscopic examination circuit, and described fluoroscopic examination circuit comprises CPU, and described CPU is connected with photosignal IV modular converter, signal amplification filtering module and AD modular converter in turn, and described photoelectric sensor is connected with described CPU.
Preferably, described control circuit also comprises mutual circuit, described mutual circuit comprises the signal acquisition module, data memory module, data transmission module, result display module and the human-computer interaction module that are connected with described CPU, and described housing is provided with the scanning window that is equipped with described signal acquisition module, the display screen being equipped with described result display module and the button portion being equipped with described human-computer interaction module.
Preferably, described fluoroscopic examination circuit is located on fluoroscopic examination circuit board, and described mutual circuit is located on mutual circuit board, and described fluoroscopic examination circuit board and mutual circuit board are located in housing.
The utility model provides a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle of optimizing structure, by optical de-tection means and control circuit are set in housing, test strips is inserted from the test strips insert port of housing, control circuit control optical detecting module detects the fluorescence intensity of the subject matter to be measured in test strips, scanning sample, gather the fluorescent marker transmitting light intensity on fluorescent test paper strip, spectra re-recorded sample information curve also shows, by control circuit, fluorescence intensity is analyzed, obtain the concentration of subject matter, wherein be located at photoelectric sensor both sides excitation source entrance port relative closure and be symmetrical arranged centered by the axis of the entrance port of photoelectric sensor, the interference that has ensured fluoroscopic examination is as far as possible little, and fluorescence excitation intensity is larger.The fluorescence that equipment of the present utility model not only can be eliminated substrate in sample equally disturbs, can also eliminate the signal such as environmental background light, space electromagnetic wave power frequency interference, promote and detect fluorescent measure signal intensity, possess the advantage that conventional fluorescence detection method cannot complete, the fluorescence intensity that can be applicable to the field subject matters such as biology, chemistry, medical science detects.
Brief description of the drawings
Fig. 1 is front view structural representation of the present utility model;
Fig. 2 is side view structural representation of the present utility model;
Fig. 3 is vertical view structural representation of the present utility model;
Fig. 4 is the stereographic map structural representation of optical de-tection means of the present utility model.
Embodiment
Below in conjunction with embodiment, the utility model is described in further detail, but protection domain of the present utility model is not limited to this.
As shown in the figure, the utility model relates to a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle, comprise housing 1, described housing 1 sidepiece is provided with test strips insert port 2, in described housing 1, be provided with optical de-tection means and control circuit, described optical de-tection means is connected with control circuit, described optical de-tection means also comprises the test strips mounting table 3 being equipped with described test strips insert port 2 and is located in turn guiding mechanism 4 and the optical detecting module of test strips mounting table 3 tops, and described optical detecting module is connected with stepper motor 5 by screw pair; Described optical detecting module comprises detection pedestal 6, described detection pedestal 6 is provided with photoelectric sensor 7 and is located at the excitation source entrance port 8 of photoelectric sensor 7 both sides, and described excitation source entrance port 8 is symmetrical arranged centered by the axis of the entrance port of photoelectric sensor 7; Described stepper motor 5, photoelectric sensor 7 are connected with described control circuit.
In the utility model, fluorescence detection device mainly comprises housing 1, interior optical de-tection means and the control circuit of arranging of housing 1, test strips is inserted from the test strips insert port 2 of housing 1, control circuit control optical detecting module to the fluorescence intensity of the subject matter to be measured in test strips detect, scanning sample, gather the fluorescent marker transmitting light intensity on fluorescent test paper strip, spectra re-recorded sample information curve also shows, by control circuit, fluorescence intensity is analyzed, obtained the concentration of subject matter.
In the utility model, optical de-tection means comprises test strips mounting table 3 and is located in turn guiding mechanism 4 and the optical detecting module of test strips mounting table 3 tops, test strips mounting table 3 is for placing the test strips that is provided with subject matter to be measured, and optical detecting module is located at guiding mechanism 4 tops and is driven the propelling of taking exercises in direction by screw pair by control circuit control step motor 5 on guiding mechanism 4.
In the utility model, described optical detecting module comprises detection pedestal 6, detects the excitation source entrance port 8 that pedestal 6 is provided with photoelectric sensor 7 and is located at photoelectric sensor 7 both sides.Optical detecting module of the present utility model is two light source reflecting typed optical detecting modules, relate to the light path design of biconjugate structure, in practical work process, taking the LED of high stability as excitation source, by 8 incidents of excitation source entrance port, and detect the fluorescent intensity of current scanning position to be located at photoelectric sensor 7 in the middle of excitation source, photoelectric sensor 7 is by control circuit control, communication is returned to control circuit and carry out analyzing and processing, finally obtain the concentration data of subject matter.
In the utility model, in order to ensure that photoelectric sensor 7 is perpendicular to test strips mounting table 3, and the axis of the axis of the entrance port of photoelectric sensor 7 and 2 excitation source entrance ports 8 is intersected on test strips mounting table 3, therefore when excitation source entrance port 8 is symmetrical arranged centered by the axis of the entrance port of photoelectric sensor 7, the design of entirety is the most reasonable, also can reach best fluorescence excitation and scanning sample and obtain the effect of fluorescence intensity.
In the utility model, the angle of the axis of the axis of the entrance port of photoelectric sensor 7 and excitation source entrance port 8 is set to 15 °～45 °, simultaneously, consider interference of light, in the utility model, the angle of the axis of the axis of the entrance port of photoelectric sensor 7 and excitation source entrance port 8 is set to 45 °.
Described photoelectric sensor 7 is perpendicular to described test strips mounting table 3, and the axis of the axis of the entrance port of described photoelectric sensor 7 and 2 excitation source entrance ports 8 is intersected on test strips mounting table 3.
In the utility model, photoelectric sensor 7, perpendicular to the test strips mounting table 3 as plane to be measured, is in order to ensure the accurate of sampled scan and feedback result; As entrance port 8 central axis of excitation source of two light sources and the central axis of photoelectric sensor 7 be intersected in test strips mounting table 3 be detection plane a bit, ensure the consistent of the occurrence positions of fluorescence and sampled scan position, can utilize more accurately photoelectric sensor 7 to detect the fluorescence intensity level of current scanning position.
Described photoelectric sensor 7 is photodiode.
In the utility model, photoelectric sensor 7 is the employing photovalve commonly used sensors as detecting element, and it can convert the variation of light signal to electric signal by photovalve by light signal.In the utility model, be all suitable for as long as light signal can be converted to the photoelectric sensor of electric signal, generally, adopt photodiode to satisfy the demands.
Described excitation source is light emitting diode.
In the utility model, excitation source can be the ordinary light source as light emitting diode.Meanwhile, laser is also suitable for.
In the utility model, employing LED completes the operation of excitation source, because of advantages such as LED have band width, and temperature coefficient is low, and scattering angle is little.
8 places, described excitation source entrance port are provided with inserted slot.
In the utility model, need to change according to the specific demand of fluorescent marker LED and the optical filter of different wave length, then detect the fluorescent intensity of current scanning position with photoelectric sensor 7, in excitation source entrance port, 8 places arrange inserted slot, can change at any time according to specific demand LED and the optical filter of different wave length, the fluorescence that completes different subject matters to be measured triggers operation.
Described guiding mechanism 4 is guide rail, and the guide direction of described guide rail is consistent with the guide direction of test strips mounting table 3.
In the utility model, guiding mechanism 4 can be set to the form that leads arbitrarily, only need complete guiding operation.Because the position of test strips mounting table 3 is certain and direction is single, therefore generally, guiding mechanism 4 is set to guide rail, and the guide direction of guide rail is consistent with the guide direction of test strips mounting table 3, ensures optical detecting module each point motion directly over test strips mounting table 3 always.
Described control circuit comprises fluoroscopic examination circuit, and described fluoroscopic examination circuit comprises CPU, and described CPU is connected with photosignal IV modular converter, signal amplification filtering module and AD modular converter in turn, and described photoelectric sensor 7 is connected with described CPU.
In the utility model, owing to still having certain undesired signal by the result of photoelectric sensor 7 scanning samples, therefore need to transfer to fluoroscopic examination circuit to do certain filtering and conversion.In the utility model, the information of scanning sample is fed back to CPU by photoelectric sensor 7, and by photosignal IV modular converter by the optical signal modulation of light source to certain frequency and change into effective voltage signal, then disturb and finally convert digital signal by AD modular converter fluorescence intensity signals to by simulating signal by signal amplification filtering module filtering low-frequency noise and power frequency, obtain being converted to the fluorescence intensity of digital signal and carry out analytical calculation, finally obtaining the actual concentrations value of subject matter to be measured.
Described control circuit also comprises mutual circuit, described mutual circuit comprises the signal acquisition module, data memory module, data transmission module, result display module and the human-computer interaction module that are connected with described CPU, and described housing 1 is provided with the scanning window 9 that is equipped with described signal acquisition module, the display screen 10 being equipped with described result display module and the button portion 11 being equipped with described human-computer interaction module.
In the utility model, the mutual circuit that control circuit comprises comprises signal acquisition module, data memory module, data transmission module, result display module and human-computer interaction module, scanning window 9 on signal acquisition module cooperation housing 1 can be for gathering one dimension code, the signals such as Quick Response Code, data memory module and data transmission module are for managing data message and can carrying out data transmission by USB or com interface and host computer, result display module is engaged in housing 1 and is provided with display screen 10, for showing current fluorescence triggering situation, fluorescence intensity level etc., human-computer interaction module can offer the real-time process information of user or default value by be equipped with button portion 11 on housing 1.
In the utility model, arranging of hardware mutual circuit and that coordinate can provide the utility model product more extending space, even if be more conducive to the mutual of data and preserve.
Described fluoroscopic examination circuit is located on fluoroscopic examination circuit board, and described mutual circuit is located on mutual circuit board, and described fluoroscopic examination circuit board and mutual circuit board are located in housing 1.
In the utility model, for layout rationally, fluoroscopic examination circuit is located on fluoroscopic examination circuit board, mutual circuit is located on mutual circuit board, be divided into two circuit boards, fluoroscopic examination circuit board and mutual circuit board are located in housing 1, have rationally been utilized the space in housing 1, be also convenient to maintenance and the maintenance of circuit.
In the utility model, can be by selecting the chromatograph test strip based on immunochromatography fluorescent technique, add the detection sample of variable concentrations, treat test strips bone dry its control line of repeated detection (C), slotted line signal (T) afterwards, investigate the stability of its T/C value, due to fluorescent bleach effect, C line, the absolute light intensity of T line all can decay, and T/C value keeps relative stability, can reach 0.5% detection sensitivity index.
The utility model has solved in prior art, exciting light irradiates and inspires in the process of fluorescence, except measuring the fluorescence of subject matter transmitting, that is to say outside the fluorescence information that is marked at the fluorchrome on sample, also comprise the large class interference of environmental background fluorescence and impurity fluorescence excitation two fluorescence, and cause because interfering material has uncertainty, environmental background disturbs also has uncertainty, therefore can not affirm and eliminate all interfering material fluorescence excitations completely, and most methods can not be eliminated the environmental background light interference that same fluorchrome wave band overlaps completely, also has the problem of detection system light leak and electromagnetic interference (EMI) etc., by optical de-tection means and control circuit are set in housing, test strips is inserted from the test strips insert port of housing, control circuit control optical detecting module detects the fluorescence intensity of the subject matter to be measured in test strips, scanning sample, gather the fluorescent marker transmitting light intensity on fluorescent test paper strip, spectra re-recorded sample information curve also shows, by control circuit, fluorescence intensity is analyzed, obtain the concentration of subject matter, wherein be located at photoelectric sensor both sides excitation source entrance port relative closure and be symmetrical arranged centered by the axis of the entrance port of photoelectric sensor, the interference that has ensured fluoroscopic examination is as far as possible little, and fluorescence excitation intensity is larger.The fluorescence that equipment of the present utility model not only can be eliminated substrate in sample equally disturbs, can also eliminate the signal such as environmental background light, space electromagnetic wave power frequency interference, promote and detect fluorescent measure signal intensity, possess the advantage that conventional fluorescence detection method cannot complete, the fluorescence intensity that can be applicable to the field subject matters such as biology, chemistry, medical science detects.
Claims (9)
1. the fluorescence detection device based on mutually balanced multiple-frequency modulation principle, comprise housing, described housing sidepiece is provided with test strips insert port, in described housing, be provided with optical de-tection means and control circuit, described optical de-tection means is connected with control circuit, it is characterized in that: described optical de-tection means also comprises the test strips mounting table being equipped with described test strips insert port and be located in turn guiding mechanism and the optical detecting module of test strips mounting table top, described optical detecting module is connected with stepper motor by screw pair; Described optical detecting module comprises detection pedestal, and described detection pedestal is provided with photoelectric sensor and is located at the excitation source entrance port of photoelectric sensor both sides, and described excitation source entrance port is symmetrical arranged centered by the axis of the entrance port of photoelectric sensor; Described stepper motor, photoelectric sensor are connected with described control circuit.
2. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 1, it is characterized in that: described photoelectric sensor is perpendicular to described test strips mounting table, and the axis of the axis of the entrance port of described photoelectric sensor and 2 excitation source entrance ports is intersected on test strips mounting table.
3. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 1, is characterized in that: described photoelectric sensor is photodiode.
4. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 1, is characterized in that: described excitation source is light emitting diode.
5. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 1, is characterized in that: described excitation source entrance port place is provided with inserted slot.
6. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 1, is characterized in that: described guiding mechanism is guide rail, and the guide direction of described guide rail is consistent with the guide direction of test strips mounting table.
7. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 1, it is characterized in that: described control circuit comprises fluoroscopic examination circuit, described fluoroscopic examination circuit comprises CPU, described CPU is connected with photosignal IV modular converter, signal amplification filtering module and AD modular converter in turn, and described photoelectric sensor is connected with described CPU.
8. a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle according to claim 7, it is characterized in that: described control circuit also comprises mutual circuit, described mutual circuit comprises the signal acquisition module, data memory module, data transmission module, result display module and the human-computer interaction module that are connected with described CPU, and described housing is provided with the scanning window that is equipped with described signal acquisition module, the display screen being equipped with described result display module and the button portion being equipped with described human-computer interaction module.
9. according to a kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle described in claim 7 or 8, it is characterized in that: described fluoroscopic examination circuit is located on fluoroscopic examination circuit board, described mutual circuit is located on mutual circuit board, and described fluoroscopic examination circuit board and mutual circuit board are located in housing.
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| CN201420409350.9U CN203981588U (en) | 2014-07-23 | 2014-07-23 | A kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle |
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| CN201420409350.9U CN203981588U (en) | 2014-07-23 | 2014-07-23 | A kind of fluorescence detection device based on mutually balanced multiple-frequency modulation principle |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105259148A (en) * | 2015-11-02 | 2016-01-20 | 深圳市锦瑞电子有限公司 | Fluorescence immunoassay quantitative analyzer |
| CN109828104A (en) * | 2019-03-05 | 2019-05-31 | 中国科学院合肥物质科学研究院 | A kind of the reagent bar detection device and detection method of without motion mechanism |
| CN113325184A (en) * | 2021-05-10 | 2021-08-31 | 棒糖科技(杭州)股份有限公司 | Multi-hormone detection equipment and method of movable sensing acquisition system |
| CN113376384A (en) * | 2021-05-19 | 2021-09-10 | 棒糖科技(杭州)股份有限公司 | Method for calculating hormone concentration of fluorescent test paper |
-
2014
- 2014-07-23 CN CN201420409350.9U patent/CN203981588U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105259148A (en) * | 2015-11-02 | 2016-01-20 | 深圳市锦瑞电子有限公司 | Fluorescence immunoassay quantitative analyzer |
| CN109828104A (en) * | 2019-03-05 | 2019-05-31 | 中国科学院合肥物质科学研究院 | A kind of the reagent bar detection device and detection method of without motion mechanism |
| CN113325184A (en) * | 2021-05-10 | 2021-08-31 | 棒糖科技(杭州)股份有限公司 | Multi-hormone detection equipment and method of movable sensing acquisition system |
| CN113376384A (en) * | 2021-05-19 | 2021-09-10 | 棒糖科技(杭州)股份有限公司 | Method for calculating hormone concentration of fluorescent test paper |
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Granted publication date: 20141203 |