CN201166662Y - Full-automatic biochemical analysizer with outlay type reaction disk signal sampling apparatus - Google Patents
Full-automatic biochemical analysizer with outlay type reaction disk signal sampling apparatus Download PDFInfo
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- CN201166662Y CN201166662Y CNU2008200319619U CN200820031961U CN201166662Y CN 201166662 Y CN201166662 Y CN 201166662Y CN U2008200319619 U CNU2008200319619 U CN U2008200319619U CN 200820031961 U CN200820031961 U CN 200820031961U CN 201166662 Y CN201166662 Y CN 201166662Y
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Abstract
The utility model discloses an external automatic biochemistry analyzer of a reaction disk signal sampling device, which belongs to a medical instrument. The external automatic biochemistry analyzer comprises reaction disk parts, all of which are arranged in the chassis of the biochemistry analyzer. The external automatic biochemistry analyzer is characterized in that the reaction disk parts comprise a reaction disk bottom board (1), a reaction disk (2), a driving motor (3), a synchronous belt (4), a synchronous pulley (5), a reaction disk shaft (6), a reaction disk thermal container (7) and a reaction cup frame (8), wherein, an annular reaction cup groove (11) is formed on the reaction cup frame (8); a source inlet (12) is formed on the outer side of the reaction cup groove (11); one end of each of eight optical fibers matched with eight color filters is respectively arranged in an optical fiber mounting hole (13), the other ends of the eight optical fibers are correspondingly fixed in eight optical fiber locating sleeves (16) by passing through the reaction disk thermal container (7); the optical fiber locating sleeves (16) are arranged on a signal plate fixed mount (15); and the signal plate fixed mount (15) is fixed on the reaction disk bottom board (1), and is positioned on the outer side of the reaction disk thermal container (7). The external automatic biochemistry analyzer has the advantages of good pollution preventing effect and simple structure.
Description
Technical field
The utility model relates to a kind of medicine equipment, especially a kind of Biochemical Analyzer, specifically a kind of external type full-automatic biochemical analysizer for response disk signal sampling apparatus.
Background technology
Biochemical Analyzer (Chemistry Analyzer) is one of important analysis instrument that often uses in the clinical examination, and it is by measuring various biochemical indicators to the analysis of blood or other body fluid: as transaminase, haemoglobin, albumin, total protein, cholesterol, flesh liver, glucose, Phos, diastase, calcium etc.In conjunction with other clinical datas, carry out analysis-by-synthesis, can the assisted diagnosis disease, organ dysfunction is made evaluation, differentiate the concurrent factor, and the benchmark of decision treatment from now on etc.
In Biochemical Analyzer, analytical approach commonly used is to utilize eight color filters to carry out signal sampling and analyzed according to the signal that collects by computing machine, draw corresponding physical and chemical index, in order to obtain the sampled signal of eight different-wavebands, eight color filters need be installed on reaction tray, each color filter links to each other with corresponding signal sampling plate, must on the reaction plate rail, process eight mounting holes for this reason, be directed on the reaction plate rail by the light of optical fiber eight corresponding color filters that mounting hole passed through, handle by sending into computer processing system after the sampling of signal sampling plate again, because signal plate and color filter are installed on the reaction plate rail, its mounting groove next-door neighbour reaction box, therefore at the blood sample of in reaction box, annotating, be easy to blood sample in reactant liquor and the cleaning process, reactant liquor or cleaning fluid spread and splash in the signal plate mounting groove, color filter and signal plate are polluted, and color filter and signal plate contaminated after, light then influence the accuracy of data, heavy then cause its damage, must in time change, make use cost increase, must be very careful when therefore using, simultaneously because each reaction box must be through eight samplings, therefore there is the time difference in the sampling, also can has influence on the consistance and the repeatability of data.
Summary of the invention
The purpose of this utility model is in use to be subject to blood sample, reactant liquor or contaminated cleaning solution and to analyze the problem of data poor repeatability at the color filter of existing Biochemical Analyzer and signal plate, design a kind of can eight wave band datas of disposable detection and color filter and the signal plate external type full-automatic biochemical analysizer for response disk signal sampling apparatus that can not be polluted fully.
The technical solution of the utility model is:
A kind of external type full-automatic biochemical analysizer for response disk signal sampling apparatus, comprise the reaction tray parts, these reaction tray parts are installed in the casing of Biochemical Analyzer, it is characterized in that described reaction tray parts comprise reaction tray base plate 1, reaction tray 2, drive motor 3, be with 4 synchronously, synchronous pulley 5, reaction tray axle 6, reaction tray insulation can 7, reaction glass stand 8, drive motor 3 is installed in the bottom of reaction tray base plate 1, reaction tray axle 6 is installed on the reaction tray base plate 1, synchronous pulley 5 is installed on the lower end of reaction tray axle 6, reaction tray 2 is installed on the upper end of reaction tray axle 6 and with its synchronous rotation, synchronous pulley 5 is by being with 4 to link to each other with drive motor 3 synchronously, reaction tray insulation can 7 is installed on the reaction tray base plate 1, reaction tray 2, the upper end of reaction tray axle 6 all is arranged in reaction tray insulation can 7; Reaction glass stand 8 is paid for 10 first by the reaction tray that links to each other with reaction tray base plate 1 and is installed in the reaction tray insulation can 7, reaction glass stand 8 is provided with an annular reaction cup groove 11, be provided with light source inlet 12 in the outside of reaction cup groove 11, be provided with an optical fiber mounting hole 13 at the inboard of reaction cup groove 11 and the described light source 12 relative position places that enter the mouth, one end of eight optical fiber 17 that match with eight color filters 14 is installed in the described optical fiber mounting hole 13, the other end of eight optical fiber 17 passes reaction tray insulation can 7 and is fixed in eight corresponding fiber orientation covers 16, described fiber orientation cover 16 is installed on the signal plate fixed mount 15, and signal plate fixed mount 15 is fixed on the reaction tray base plate 1 and is positioned at the outside of reaction tray insulation can 7; On signal plate fixed mount 15, a side of fiber orientation cover 16 installs color filter 14 and the signal dash receiver that promising analytic system provides signal.
Described signal plate fixed mount 15 curved structures, described eight fiber orientation cover 16 is distributed on the described signal plate fixed mount 15.
Be provided with removable cover 18 on the top of described reaction tray insulation can 7, on its sidewall, be provided with light source mounting hole 19 with the described light source 12 relative position places that enter the mouth.
The beneficial effects of the utility model:
The utility model has at first adopted the method that color filter and signal plate are separated with reaction tray on Biochemical Analyzer, by optical fiber light signal is directed to outside the reaction tray, from according to pollution and the damage avoided as the color filter and the signal of the most important parts of analyser, can save the operation and maintenance expense (about 1000 yuan of the replacement cost of each color filter) of equipment greatly, and can reduce the sealing grade and the manufacture difficulty of equipment greatly, reduce the device fabrication expense.
The utility model first will be originally need divide 8 times same sample to be sampled respectively and changed disposable sampling into, promptly by original eight-in-one, change one minute eight into, the accuracy of sampling and the repeatability of data have been improved greatly, because blood sample can be subjected to the interference of various factors at any time in rotation process, 8 data that the data that 8 time gathers and time gather have certain difference, can influence the accuracy of data to a certain extent.
The utility model can prevent from still to carry out because of color filter or signal plate are contaminated data acquisition the data that may cause inaccurate, and the false diagnosis that causes thus prevents the generation of related medical accident.
Of the present utility model simple in structure, the installation of color filter and signal plate, change also more convenient, original because the mounting groove in the reaction plate rail is very little, very inconvenient during replacing, and behind the utility model employing external structure, even need replacing also very convenient, the operating space is bigger.
Use reaction tray parts of the present utility model can on the reaction tray support, save the mounting groove that originally is used to install color filter and signal plate, make that the structure of reaction plate rail is also more simple, make convenient.
Description of drawings
Fig. 1 is the structural representation of reaction tray parts of the present utility model.
Fig. 2 is the structural representation of signal plate fixed mount of the present utility model.
Fig. 3 is the plan structure synoptic diagram of Fig. 2.
Fig. 4 is the A-A cut-open view rotation diagram of Fig. 3.
Embodiment
Below in conjunction with drawings and Examples the utility model is further described.
Shown in Fig. 1,2,3,4.
A kind of external type full-automatic biochemical analysizer for response disk signal sampling apparatus, comprise the reaction tray parts, these reaction tray parts are installed in the casing of Biochemical Analyzer, described reaction tray parts comprise reaction tray base plate 1, reaction tray 2, drive motor 3, be with 4 synchronously, synchronous pulley 5, reaction tray axle 6, reaction tray insulation can 7, reaction glass stand 8 etc., as shown in Figure 1, reaction tray base plate 1 is installed on the bottom plate stanchions 20,20 of bottom plate stanchions are fixed in the casing of Biochemical Analyzer, drive motor 3 is installed in the bottom of reaction tray base plate 1, reaction tray axle 6 is installed on the reaction tray base plate 1 by the axle sleeve 9 that is installed on the reaction tray base plate 1, earlier axle sleeve 9 is fixed on the reaction tray base plate 1 during installation, bearing holder (housing, cover) is contained on the reaction tray axle 9 again, at last reaction tray axle 9 is adorned together with bearing and axle sleeve 9 in get final product, synchronous pulley 5 is installed on the lower end of reaction tray axle 6, reaction tray 2 is installed on the upper end of reaction tray axle 6 and with its synchronous rotation, synchronous pulley 5 is by being with 4 to link to each other with drive motor 3 synchronously, reaction tray insulation can 7 is installed on the reaction tray base plate 1, its top is provided with removable cover 18, reaction tray 2, the upper end of reaction tray axle 6 all is arranged in reaction tray insulation can 7; Reaction glass stand 8 is paid for 10 first by the reaction tray that links to each other with reaction tray base plate 1 and is installed in the reaction tray insulation can 7, reaction glass stand 8 is provided with an annular reaction cup groove 11, the concrete mounting structure of reaction cup can adopt the structure identical with existing equipment, being about to reaction plate is installed in one by one on the arcuation mounting blocks arcuation mounting blocks and blocks and be inserted on the reaction tray 2, when reaction tray 2 is rotated like this, promptly having reaction cup rotates in reaction cup groove 11 successively by reacting on the glass stand 8, the light source inlet 12 of the arranged outside of reaction cup groove 11, have the light source mounting hole 19 that light source is installed at reaction tray insulation can 7 sidewall relative position places, be provided with an optical fiber mounting hole 13 at the inboard of reaction cup groove 11 and the described light source 12 relative position places that enter the mouth, one end of eight optical fiber 17 that match with eight color filters 14 is installed in the described optical fiber mounting hole 13, the other end of eight optical fiber 17 passes reaction tray insulation can 7 and is fixed in eight corresponding fiber orientation covers 16, described 8 fiber orientation cover 16 is installed on the arc signal plate fixed mount 15 equably, as Fig. 2,3, shown in 4, signal plate fixed mount 15 is fixed on the reaction tray base plate 1 and is positioned at the outside of reaction tray insulation can 7; On signal plate fixed mount 15, a side of fiber orientation cover 16 installs color filter 14 and the signal dash receiver that promising analytic system provides signal.
The prior aries that maybe can adopt all same as the prior art such as the installation and positioning structure of the color filter that Biochemical Analyzer of the present utility model does not relate to, signal plate and mounting means thereof and light source, monochromator, detecting device, sample adding system, purging system, temperature control system and interpretation software are realized.Respectively these parts and system are done a simply introduction below.
1. light source
Desirable light source should produce the constant light intensity degree in whole wavelength coverage, noise is low, long-term stability.Regrettably in fact do not have such light source, therefore, need choose different light sources according to the difference of service band.Deuterium lamp can produce the continuous spectrum of certain intensity in the ultraviolet region, also can provide the light intensity of usefulness in the visible range.Although present deuterium lamp noise is very low, the noise of lamp is still the principal element of restriction whole instrument noise level.Halogen tungsten lamp can produce stronger continuous spectrum in part ultraviolet region and whole visible-range, noise is low, and it is little to drift about.Therefore Biochemical Analyzer of the present utility model is the best to adopt halogen tungsten lamp as light source.
2. monochromator
Monochromator is the assembly that the light of different wave length is dispersed with different angles, and the difference of pressing dispersion element can be divided into prism monochromator, grating monochromator and optical filtering chip monochromator.
Prism not only simply but also cheap, but its chromatic dispersion is crooked and nonlinear, the long wave dispersive power is little, therefore shortwave dispersive power height wishes to get identical spectra intensity, slit width will change with wavelength, and each spectrum line is different at interval, is non-normal spectrum.
The dispersive power of grating is big, and dispersion angle and wavelength are linear, the resolution height, and spectral range is wide.But, must note the influence of the folded level of spectrum, detection sensitivity and optical layout factors such as (preceding beam split or back beam split) when adopting the instruments design of grating.
The optical filter low price by scientific and rational design, adopt optical filter beam split mode can obtain the effect equal with grating beam splitting fully, so the monochromator that the utility model adopts is an optical filter.
3. detecting device
The effect of detecting device is that light signal is converted to electric signal.It is wide that desirable detecting device should have the range of linearity, and noise is low, highly sensitive.So the detecting device of Biochemical Analyzer is generally photomultiplier or photodiode.The character of photomultiplier cathode material has determined its spectrum sensitivity.Photomultiplier has good sensitivity in the ultraviolet-visible scope, it is very high to the sensitivity of the low light level.But in spectroscopy applications, high sensitivity is used to measure the low concentration material, is accurately to detect the minute differences of blank and sample room, and detecting device necessary noise when strong signal is low.Photodiode (or photodiode array) is widely used in Biochemical Analyzer, is the mainstream technology that present medium-to-high grade Biochemical Analyzer adopts.Photodiode detects wide dynamic range, and is more durable than photomultiplier as solid-state components.Early stage photodiode is lower in ultraviolet region sensitivity, but this problem overcomes, the sensing range of silicon photoelectric diode is 170nm～1100nm approximately, therefore, can adopt photodiode as detecting device of the present utility model during concrete enforcement, utilize its spectral signal to change, make it become the electric signal that calculates function identification and handle the corresponding wave band sensed.
4. sample adding system
The precision of sample adding system directly influences measurement result, and therefore, sample adding system also is one of vitals of Biochemical Analyzer.
Sample adding system is divided into blood sample sample adding system and reagent sample adding system, and both are on principle and structure and indistinction.The application of sample process is made up of initialization procedure, suction sample process, stock layout process and cleaning process.
The application of sample precision is generally by following technique guarantee:
(1) reasonably the liquid road is designed and interconnection technique;
(2) level detection technology: sampling needle can be responded to liquid level, detects can stop after inserting appropriate depth behind the liquid level;
(3) whatever you like tracking technique: sampling needle is according to how many automatic decline degree of depth of adjusting of institute's dispense liquid;
(4) stop up detection: probe can detect celloglobulin or the stifled pin of other foreign material in blood or the reagent automatically, handles according to built-in pressoreceptor behind the stifled pin.
And these technology all have proven technique to adopt for using for reference with direct in existing blood sample analysis instrument.
5. purging system
In Biochemical Analyzer, reaction cup is cleaned and can be passed through two kinds of schemes realizations, i.e. interior cleaning reaction cup of machine and replacing reaction cup automatically.
Cleaning reaction cup mode in the employing machine, reaction cup is used repeatedly.Cleaning process comprises and blots reactant liquor, injects acidic cleaner, blots acidic cleaner, injects alkaline cleaner, blots alkaline cleaner, injects steps such as deionized water (having repeatedly), dry reaction cup.The effect of cleaning is directly determining the pollution of carrying of instrument.The disadvantage of cleaning in the machine is be difficult to guarantee reaction cup is thoroughly cleaned up, so the error that the reaction cup pollution causes to be inevitable; And water consumption more also is a problem.
Automatically changing the reaction cup mode is to adopt disposal reaction cup, so the pollution meeting of carrying of instrument reduces greatly; Simultaneously, owing to reduced the process of repeated washing, can further improve the reliability of instrument, simultaneously, the water consumption of instrument also can reduce greatly.For the utility model, owing to will easily pollute with flimsy optical filter and signal-processing board and move apart reaction cup, can not pollute and damage even therefore there is cleaning fluid to flow in the reaction cup groove in the cleaning process yet, therefore, specifically adopt which kind of cleaning way to be determined as required.
6. temperature control system
All kinds of biochemical reactions especially enzyme are very responsive to temperature fluctuation, need a stationary temperature, just can obtain reliably, result accurately, generally require the temperature fluctuation of reaction chamber is controlled at ± 0.1 ℃.The method of present more employing is free vapour method, thermostatic water-bath method, constant temperature liquid heating etc.Therefore, the heating of insulation casing 7 of the present utility model can adopt in the said method any to be realized.
7. software systems
The target of software systems is to be user provide convenience practicality, easily study, friendly interface, maneuverable software.
The function that software should possess mainly contains: the one, for the user provides the interface of operating instrument, to realize the editor of project, sample/reagent setting, the application of project, execution, result's output and historical record inquiry etc.; The 2nd, the work of control instrument various piece realizes various biochemical analysis methods and some subsidiary functions, and for a biochemical analyzer, automaticity is high more, and the function of instrument is also strong more; The 3rd, the analyzing and processing of data and calculating, as patient information and original data storage, result of laboratory test summary report, report out of control, the drawing of Quality Control data computation, the analysis of Quality Control retrospective examination, Quality Control thing and Quality Control data management, or the like.
The utility model other do not relate to the part prior art that maybe can adopt all same as the prior art realized.
Claims (3)
1, a kind of external type full-automatic biochemical analysizer for response disk signal sampling apparatus, comprise the reaction tray parts, these reaction tray parts are installed in the casing of Biochemical Analyzer, it is characterized in that described reaction tray parts comprise reaction tray base plate (1), reaction tray (2), drive motor (3), be with synchronously (4), synchronous pulley (5), reaction tray axle (6), reaction tray insulation can (7), reaction glass stand (8), drive motor (3) is installed in the bottom of reaction tray base plate (1), reaction tray axle (6) is installed on the reaction tray base plate (1), synchronous pulley (5) is installed on the lower end of reaction tray axle (6), reaction tray (2) is installed on the upper end of reaction tray axle (6) and with its synchronous rotation, synchronous pulley (5) links to each other with drive motor (3) by being with (4) synchronously, reaction tray insulation can (7) is installed on the reaction tray base plate (1), reaction tray (2), the upper end of reaction tray axle (6) all is arranged in reaction tray insulation can (7); Reaction glass stand (8) is paid for (10) first by the reaction tray that links to each other with reaction tray base plate (1) and is installed in the reaction tray insulation can (7), reaction glass stand (8) is provided with an annular reaction cup groove (11), be provided with light source inlet (12) in the outside of reaction cup groove (11), inboard and described light source inlet (12) relative position place at reaction cup groove (11) are provided with an optical fiber mounting hole (13), one end of eight optical fiber (17) that match with eight color filters (14) is installed in the described optical fiber mounting hole (13), the other end of eight optical fiber (17) passes reaction tray insulation can (7) and is fixed in corresponding eight fiber orientation covers (16), described fiber orientation cover (16) is installed on the signal plate fixed mount (15), and signal plate fixed mount (15) is fixed on the outside that reaction tray insulation can (7) were gone up and be positioned to reaction tray base plate (1); One side last at signal plate fixed mount (15), fiber orientation cover (16) is installed color filter (14) and the signal dash receiver that promising analytic system provides signal.
2, external type full-automatic biochemical analysizer for response disk signal sampling apparatus according to claim 1, it is characterized in that the curved structure of described signal plate fixed mount (15), described eight fiber orientation covers (16) are distributed on the described signal plate fixed mount (15).
3, external type full-automatic biochemical analysizer for response disk signal sampling apparatus according to claim 1, it is characterized in that being provided with removable cover (18), on its sidewall, be provided with light source mounting hole (19) with described light source inlet (12) relative position place on the top of described reaction tray insulation can (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200319619U CN201166662Y (en) | 2008-03-06 | 2008-03-06 | Full-automatic biochemical analysizer with outlay type reaction disk signal sampling apparatus |
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| Application Number | Priority Date | Filing Date | Title |
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| CNU2008200319619U CN201166662Y (en) | 2008-03-06 | 2008-03-06 | Full-automatic biochemical analysizer with outlay type reaction disk signal sampling apparatus |
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| CNU2008200319619U Expired - Fee Related CN201166662Y (en) | 2008-03-06 | 2008-03-06 | Full-automatic biochemical analysizer with outlay type reaction disk signal sampling apparatus |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108061809A (en) * | 2017-11-27 | 2018-05-22 | 桂林优利特医疗电子有限公司 | Biochemical instruments react cup holding rack and reaction tray movement accuracy-control system |
| CN108562543A (en) * | 2018-05-03 | 2018-09-21 | 方余 | A kind of routine biochemistry analytical instrument |
| CN109269998A (en) * | 2018-11-16 | 2019-01-25 | 宁波普瑞柏生物技术股份有限公司 | A kind of light path system and detection device of specific protein analyzer |
-
2008
- 2008-03-06 CN CNU2008200319619U patent/CN201166662Y/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108061809A (en) * | 2017-11-27 | 2018-05-22 | 桂林优利特医疗电子有限公司 | Biochemical instruments react cup holding rack and reaction tray movement accuracy-control system |
| CN108562543A (en) * | 2018-05-03 | 2018-09-21 | 方余 | A kind of routine biochemistry analytical instrument |
| CN108562543B (en) * | 2018-05-03 | 2019-06-28 | 广东冉盛科学仪器有限公司 | A kind of routine biochemistry analysis instrument |
| CN109269998A (en) * | 2018-11-16 | 2019-01-25 | 宁波普瑞柏生物技术股份有限公司 | A kind of light path system and detection device of specific protein analyzer |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20081217 Termination date: 20110306 |