CN102793728A - High-frequency oscillation wall-broken ganoderma lucidum spore powder - Google Patents

High-frequency oscillation wall-broken ganoderma lucidum spore powder Download PDF

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Publication number
CN102793728A
CN102793728A CN2012103045448A CN201210304544A CN102793728A CN 102793728 A CN102793728 A CN 102793728A CN 2012103045448 A CN2012103045448 A CN 2012103045448A CN 201210304544 A CN201210304544 A CN 201210304544A CN 102793728 A CN102793728 A CN 102793728A
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CN
China
Prior art keywords
spore powder
ganoderma spore
oscillation
broken
order
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN2012103045448A
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Chinese (zh)
Inventor
王其初
张洪彦
魏吉香
范翠玲
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ANHUI HARBAUGH PHARMACEUTICAL Co Ltd
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ANHUI HARBAUGH PHARMACEUTICAL Co Ltd
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Priority to CN2012103045448A priority Critical patent/CN102793728A/en
Publication of CN102793728A publication Critical patent/CN102793728A/en
Pending legal-status Critical Current

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Abstract

Disclosed is a high-frequency oscillation wall-broken ganoderma lucidum spore powder. The high-frequency oscillation wall-broken ganoderma lucidum spore powder is prepared by the following steps: step one, preparing ganoderma lucidum spore powder; step two, drying the ganoderma lucidum spore powder; and step three, breaking the ganoderma lucidum walls with a high frequency oscillation wall-breaker to get high-frequency oscillation wall-broken ganoderma lucidum spore powder. The high frequency oscillation wall-breaker in the present invention is used for wall breaking with a wall-broken rate of no less than 98%. Due to the prevention of acid and base and high temperature, active ingredients are maximally maintained, and the absorption rate of human bodies is significantly increased. Without using chemical agents and biological preparations, new impurities are not introduced, and high purity is maintained.

Description

Higher-order of oscillation Ganoderma spore powder with cellular wall broken
Technical field
The present invention relates to a kind of Ganoderma spore powder, be specifically related to a kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken.
Background technology
Ganoderma spore powder with cellular wall broken derives from Ganoderma, and Ganoderma spore powder with cellular wall broken is after Ganoderma sporophore is reached maturity, and collects the spore of being hit by a bullet and penetrating from tube, behind breaking cellular wall, obtains.
Ganoderma spore has been assembled the elite of Ganoderma; Contain effective ingredient such as polysaccharide, triterpene; But the hard outer wall of Ganoderma spore has hindered these nutritional labelings to be absorbed by the body, and the Ganoderma spore powder behind breaking cellular wall has then improved the utilization of these bioactive ingredients greatly, and effect is optimized.
Liu Keming etc. adopt serum hemolysin algoscopy (blood clotting method), delayed allergy method (two swelling methods), Turnover of Mouse Peritoneal Macrophages to engulf the chicken red blood cell test respectively and NK cytoactive algoscopy (determination of lactate dehydrogenase method) is investigated the immunoregulation effect of Ganoderma spore powder with cellular wall broken to mice; The result shows that per os gives broken shell Ganoderma spore powder with various dose after 20 days; With matched group mutually specific energy significantly improve spleen/body weight, thymus/body weight, coagulation antibody product, mice left and right sides ear difference and macrophage phagocytic percentage rate; The prompting Ganoderma spore powder with cellular wall broken can promote the mouse immune allelotaxis, strengthens the effect of humoral immunization, cellular immunization, mononuclear-macrophage phagocytic function and NK cytoactive simultaneously again.Hence one can see that, and Ganoderma spore powder with cellular wall broken has immunoregulation effect, is a kind of more effective immunomodulator.
Wu Mingzhong etc. can strengthen dinitrofluorobenzene mice delayed hypersensitivity that causes and the effect that strengthens the reaction of mice serum hemolysin through the evidence Ganoderma spore powder with cellular wall broken; And have the effect that strengthens the reaction of mice serum hemolysin, prove that Ganoderma spore powder with cellular wall broken has immunoregulation effect.
Therefore, for the crowd of hypoimmunity, take the health care that Ganoderma spore powder with cellular wall broken can enhancing immunity.
The sporoderm-broken rate of present breaking trachytectum of glossy ganoderma mode is not high; Perhaps owing to use high temperature and soda acid to cause the active component of Ganoderma spore to be destroyed; Perhaps in chemical reagent or enzyme breaking cellular wall process, introduced new impurity, these have all caused the result of use of Ganoderma spore powder with cellular wall broken to be affected.
Summary of the invention
The invention provides a kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken; The sporoderm-broken rate of Ganoderma spore powder with cellular wall broken provided by the invention >=98% keeps active component not to be destroyed to greatest extent, has significantly improved the absorption by human body rate; And do not introduce new impurity, kept its high-purity.
The present invention realizes through following technical scheme:
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3 with the broken machine breaking cellular wall of higher-order of oscillation wall, obtains higher-order of oscillation Ganoderma spore powder with cellular wall broken.
Preferably, in said step 3, use the working form of the broken machine breaking cellular wall of higher-order of oscillation wall convertible for automatically, charge is 20L, and inlet amount is 2500~4000g/ time, and amplitude is 4~5.5mm, and grinding mode is a vibro-grinding, and the dielectric rod impact force is 5~6G.
Preferably, after said step 3, also comprise the steps: to pack said higher-order of oscillation Ganoderma spore powder with cellular wall broken and carry out cobalt 60 sterilizations, further preferred, the dosage of said cobalt 60 sterilizations is 6kGy.
The present invention adopts the broken machine of higher-order of oscillation wall to carry out breaking cellular wall, sporoderm-broken rate >=98%; Owing to avoided soda acid and high temperature, kept its active component not to be destroyed to greatest extent, significantly improved the absorption by human body rate; Do not use chemicals and biological preparation, therefore do not introduce new impurity, kept its high-purity.
Description of drawings
Fig. 1 is the technological process of production figure of higher-order of oscillation Ganoderma spore powder with cellular wall broken.
The specific embodiment
Below in conjunction with specific embodiment the present invention is elaborated.Following examples will help those skilled in the art further to understand the present invention, but not limit the present invention in any form.Should be pointed out that to those skilled in the art, under the prerequisite that does not break away from the present invention's design, can also make some distortion and improvement.These all belong to protection scope of the present invention.
Embodiment 1
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3, with the broken machine breaking cellular wall of higher-order of oscillation wall, working form is convertible for automatically, and charge is 20L, and inlet amount is 2500g/ time, and amplitude is 4mm, and grinding mode is a vibro-grinding, and the dielectric rod impact force is 5G, can obtain higher-order of oscillation Ganoderma spore powder with cellular wall broken.
Embodiment 2
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3, with the broken machine breaking cellular wall of higher-order of oscillation wall, working form is convertible for automatically; Charge is 20L, and inlet amount is 3250g/ time, and amplitude is 4.7mm; Grinding mode is a vibro-grinding, and the dielectric rod impact force is 5.5G, can obtain higher-order of oscillation Ganoderma spore powder with cellular wall broken.
Embodiment 3
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3, with the broken machine breaking cellular wall of higher-order of oscillation wall, working form is convertible for automatically, and charge is 20L, and inlet amount is 4000g/ time, and amplitude is 5.5mm, and grinding mode is a vibro-grinding, and the dielectric rod impact force is 6G, can obtain higher-order of oscillation Ganoderma spore powder with cellular wall broken.
Embodiment 4
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3, with the broken machine breaking cellular wall of higher-order of oscillation wall, working form is convertible for automatically, and charge is 20L, and inlet amount is 2500g/ time, and amplitude is 4mm, and grinding mode is a vibro-grinding, and the dielectric rod impact force is 5G;
Step 4 is packed said higher-order of oscillation Ganoderma spore powder with cellular wall broken and is carried out cobalt 60 sterilizations, and the dosage of said cobalt 60 sterilizations is 6kGy.
Embodiment 5
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3, with the broken machine breaking cellular wall of higher-order of oscillation wall, working form is convertible for automatically, and charge is 20L, and inlet amount is 3250g/ time, and amplitude is 4.7mm, and grinding mode is a vibro-grinding, and the dielectric rod impact force is 5.5G;
Step 4 is packed said higher-order of oscillation Ganoderma spore powder with cellular wall broken and is carried out cobalt 60 sterilizations, and the dosage of said cobalt 60 sterilizations is 6kGy.
Embodiment 6
A kind of higher-order of oscillation Ganoderma spore powder with cellular wall broken, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3, with the broken machine breaking cellular wall of higher-order of oscillation wall, working form is convertible for automatically, and charge is 20L, and inlet amount is 4000g/ time, and amplitude is 5.5mm, and grinding mode is a vibro-grinding, and the dielectric rod impact force is 6G;
Step 4 is packed said higher-order of oscillation Ganoderma spore powder with cellular wall broken and is carried out cobalt 60 sterilizations, and the dosage of said cobalt 60 sterilizations is 6kGy.

Claims (4)

1. a higher-order of oscillation Ganoderma spore powder with cellular wall broken is characterized in that, said higher-order of oscillation Ganoderma spore powder with cellular wall broken prepares through following method:
Step 1 is prepared Ganoderma spore powder;
Step 2, dry said Ganoderma spore powder;
Step 3 with the broken machine breaking cellular wall of higher-order of oscillation wall, obtains said higher-order of oscillation Ganoderma spore powder with cellular wall broken.
2. higher-order of oscillation Ganoderma spore powder with cellular wall broken according to claim 1 is characterized in that, in said step 3; Use the working form of the broken machine breaking cellular wall of higher-order of oscillation wall convertible for automatically; Charge is 20L, and inlet amount is 2500~4000g/ time, and amplitude is 4~5.5mm; Grinding mode is a vibro-grinding, and the dielectric rod impact force is 5~6G.
3. higher-order of oscillation Ganoderma spore powder with cellular wall broken according to claim 1 and 2 is characterized in that, after said step 3, also comprises the steps: to pack said higher-order of oscillation Ganoderma spore powder with cellular wall broken and carries out cobalt 60 sterilizations.
4. higher-order of oscillation Ganoderma spore powder with cellular wall broken according to claim 3 is characterized in that, the dosage of said cobalt 60 sterilizations is 6kGy.
CN2012103045448A 2012-08-24 2012-08-24 High-frequency oscillation wall-broken ganoderma lucidum spore powder Pending CN102793728A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103392450A (en) * 2013-08-07 2013-11-20 无锡求是生物农业有限公司 Method for collecting rice anther
CN105125595A (en) * 2015-08-07 2015-12-09 重庆市生物技术研究所有限责任公司 Ganoderma lucidum spore powder wall breaking method
CN106963790A (en) * 2017-04-24 2017-07-21 孙继勇 A kind of manufacture craft of use ultra micro nanometer technology ganoderma spove powder
CN107080759A (en) * 2017-04-28 2017-08-22 中国科学院化学研究所 The ganoderma spove powder and application of a kind of method for breaking trachytectum of glossy ganoderma and its preparation
CN109276581A (en) * 2018-09-25 2019-01-29 江苏农林职业技术学院 A kind of processing method of cicada fungus lucidium spore powder wall breaking
CN114699434A (en) * 2022-04-08 2022-07-05 抚松宇辰长白山野灵芝科技有限公司 Method for preparing ultramicro nano wall-broken ganoderma lucidum spore powder

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CN1307899A (en) * 2000-12-19 2001-08-15 高俊山 Normal temperature sporoderm crushing process of glossy ganoderma spore powder
CN1345585A (en) * 2000-09-29 2002-04-24 何煜 Process for preparing micropowder of cell rupture cable for raising Chinese medicine availability
CN1468947A (en) * 2003-06-20 2004-01-21 列 陈 Glossy ganoderma spore oil extracting and refining process
CN1471966A (en) * 2003-07-02 2004-02-04 广州宝兴生物科技有限公司 Glossy ganoderma spore powder preparing method
CN1621185A (en) * 2004-12-10 2005-06-01 华东理工大学 Method and apparatus for preparing superfine powder by super high pressure supercritical fluid micro jetting technology
CN1896221A (en) * 2006-04-24 2007-01-17 南昌大学 Persussion cavity for breaking cell wall
CN1907569A (en) * 2006-04-24 2007-02-07 南昌大学 Fluid impact cavity
CN101006856A (en) * 2006-01-25 2007-08-01 江苏省桑茧丝资源综合利用工程技术研究中心 Sterilization method of ganderoma lucium spores powder and ganderoma lucidum fruitbody
CN101239081A (en) * 2007-02-06 2008-08-13 周窑生 Composition for treating cancer and preparation thereof
CN102379908A (en) * 2011-11-11 2012-03-21 全国供销合作总社济南果蔬华德公司 Wall breaking method for fresh and live ganoderma lucidum spores

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1345585A (en) * 2000-09-29 2002-04-24 何煜 Process for preparing micropowder of cell rupture cable for raising Chinese medicine availability
CN1307899A (en) * 2000-12-19 2001-08-15 高俊山 Normal temperature sporoderm crushing process of glossy ganoderma spore powder
CN1468947A (en) * 2003-06-20 2004-01-21 列 陈 Glossy ganoderma spore oil extracting and refining process
CN1471966A (en) * 2003-07-02 2004-02-04 广州宝兴生物科技有限公司 Glossy ganoderma spore powder preparing method
CN1621185A (en) * 2004-12-10 2005-06-01 华东理工大学 Method and apparatus for preparing superfine powder by super high pressure supercritical fluid micro jetting technology
CN101006856A (en) * 2006-01-25 2007-08-01 江苏省桑茧丝资源综合利用工程技术研究中心 Sterilization method of ganderoma lucium spores powder and ganderoma lucidum fruitbody
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CN1907569A (en) * 2006-04-24 2007-02-07 南昌大学 Fluid impact cavity
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103392450A (en) * 2013-08-07 2013-11-20 无锡求是生物农业有限公司 Method for collecting rice anther
CN103392450B (en) * 2013-08-07 2015-11-04 无锡哈勃生物种业技术研究院有限公司 A kind of collection method of Rice Anther
CN105125595A (en) * 2015-08-07 2015-12-09 重庆市生物技术研究所有限责任公司 Ganoderma lucidum spore powder wall breaking method
CN105125595B (en) * 2015-08-07 2018-06-12 重庆市生物技术研究所有限责任公司 Ganoderma lucidium spore powder wall breaking method
CN106963790A (en) * 2017-04-24 2017-07-21 孙继勇 A kind of manufacture craft of use ultra micro nanometer technology ganoderma spove powder
CN107080759A (en) * 2017-04-28 2017-08-22 中国科学院化学研究所 The ganoderma spove powder and application of a kind of method for breaking trachytectum of glossy ganoderma and its preparation
CN107080759B (en) * 2017-04-28 2021-05-04 北京福纳康生物技术有限公司 Ganoderma lucidum spore wall breaking method, wall-broken ganoderma lucidum spore powder prepared by same and application of wall-broken ganoderma lucidum spore powder
CN109276581A (en) * 2018-09-25 2019-01-29 江苏农林职业技术学院 A kind of processing method of cicada fungus lucidium spore powder wall breaking
CN114699434A (en) * 2022-04-08 2022-07-05 抚松宇辰长白山野灵芝科技有限公司 Method for preparing ultramicro nano wall-broken ganoderma lucidum spore powder

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Application publication date: 20121128