CN102793167A - Rosemary antioxidant coenzyme Q10 capsule and its preparation method - Google Patents

Abstract

The invention discloses a rosemary antioxidant coenzyme Q10 capsule, which is composed of a capsule shell and contents. The capsule is characterized in that: the contents consist of the following raw materials: a rosemary antioxidant, coenzyme Q10, and rice bran oil that are in a mass ratio of 2-5:3-6:30-80. The invention also discloses a preparation method of the rosemary antioxidant coenzyme Q10 capsule. The rosemary antioxidant coenzyme Q10 capsule disclosed in the invention has the following outstanding advantages that: employment of the rosemary antioxidant which has oxidation resistance obviously superior to that of vitamin E and a low price as an adding raw material not only reduces the product cost, but also can achieve a good oxidation resisting effect, and the rosemary antioxidant is a powerful antioxidant and has an especially strong aging delaying effect; the rosemary antioxidant and the coenzyme Q10 have an excellent synergistic effect, the health care function of the coenzyme Q10 is improved and its action range is expanded; the rosemary antioxidant coenzyme Q10 capsule can be effective in treatment of heart diseases and hypertension; and the capsule can also strengthen the immune system and destroy pathogenic bacteria invading the body.

Description

Anti-oxidant coenzyme Q10 capsule of a kind of rosemary, and preparation method thereof

Technical field

The present invention relates to coenzyme Q10 capsule, anti-oxidant coenzyme Q10 capsule of particularly a kind of rosemary, and preparation method thereof.

Background technology

Rosemary, is a kind of multiduty industrial crops, therefrom can extract anti-oxidant, Rosemary Oil and medicine intermediate.Rosemary antioxidant is from rosemary plant, to extract the powdered substance that obtains, and main component is phenol, acid, the flavones ingredient with anti-oxidation function.Rosmarinus officinalis extract has efficient, nontoxic antioxidant effect; Its antioxidant effect is chemical synthesis anti-oxidant butylated hydroxyanisole (BHA) (BHA) and dibutyl hydroxy toluene (BHT) 2-4 a times; 2 times that are Tea Polyphenols also obviously are superior to vitamin E; Be best natural, can be widely used in the industries such as food, functional food, spices and flavouring and daily-use chemical industry.

In recent years, domestic and international research confirms that rosemary, has stronger inhibition killing action to staphylococcus aureus, Escherichia coli etc.; Strengthen corticocerebral process of inhibition, have good sedative, hypnosis, anticonvulsant action; Regulate blood pressure, make low blood pressure recover normal; Reduce permeability capillaceous, antiasthmatic-antitussive, treatment asthma attack and chronic bronchitis; Be used to treat in the intestines and infect, diarrhoea etc.The high antioxygenic property of rosemary, more lets the researcher extremely excited in the prospect that is demonstrated aspect the research and development cancer therapy drug, and same, the exploitation potential quality of Rosmarinus officinalis extract in the functional food field also caused scientific research personnel's abundant attention.Such as: 1) eliminate too much free radical in the human body, the structure of protection cell membrane, delaying human body caducity.A large amount of tests show that the antioxygenic property of rosemary antioxidant obviously is better than vitamin E, if be used with vitamin C and vitamin E, also have synergistic effect.The expert points out; Because rosemary antioxidant has the strong effect of dispeling free radical, can remove free radical, the quencher creating singlet oxygen by using; Can compare favourably with superoxide dismutase (SOD); And overcome these deadly defects of enzyme material unstable chemcial property such as SOD, be used for products such as health drink, oral liquid, had very big potentiality.2) reduce cholesterol, suppress atherosclerotic, the active ingredient in the Rosmarinus officinalis extract produces important function to the fat metabolism of body, can obviously suppress the rising of cholesterol level in blood plasma and the liver, prevents and treats atherosclerotic.3) lose weight, rely on its antioxidation activity, Rosmarinus officinalis extract stimulates the fat metabolism of also quickening human body, promotes lipoid substance from ight soil, to discharge, and reaches the effect of fat-reducing, and anthraquinone components such as cooperation archen can be developed the good diet products of effect.

Rice bran oil is claimed rice bran oil again, is a kind of of edible oil, with fur clothing (rice bran) refining of brown rice processing back Mi Gu.Rice bran oil has very high nutritive value, and eighty per cant unrighted acid (monounsaturated fatty acid accounts for 47%, and polybasic unsaturated fatty acid accounts for 33%) is arranged, and abundant vitamin e and other polyphenoils are arranged.Rice bran oil food back absorptivity reaches more than 90%; Aliphatic acid wherein, vitamin E, sterol, oryzanol etc. help absorption by human body; Have the cholesterol removed in the blood, reduce blood fat, promote human body beneficial effect such as grow, thereby rice bran oil is the nutrient health oil of generally acknowledging both at home and abroad.

Co-Q10 is a kind of fat-soluble antioxidant; It is one of indispensable important element of human life; The nutrition of ability human activin cell and cellular energy; Have improve body immunity, strengthen anti-oxidant, delay senility and function such as enhances human body vigor, medically be widely used in the treatment of disease of cardiovascular system.In recent years, extensively use it for nutrient and healthcare products and food additives both at home and abroad.The Co-Q10 structure is similar with vitamin E, and its content in human body can reduce with advancing age.Increasing medical research shows that Co-Q10 helps: (1) protection heart: Co-Q10 helps for cardiac muscle provides sufficient oxygen, prevention sudden heart disease, especially Co-Q10 performance key effect in the myocardial anoxia process; (2) promote energy to transform, promote energy: it is the essential energy of cells survival (like ATP) that Co-Q10 helps food conversion, makes cell keep optimum state, makes the people feel that energy is more abundant; (3) improve immunity, delay senility: Co-Q10 is the natural that cell self produces, and can stop the formation of free radical, helps to safeguard immune normal operation and delays senility.Research in recent years shows, Co-Q10 is alleviated periodontitis in prevention coronary heart disease, and also there is remarkable result treatment duodenal ulcer and gastric ulcer and allevating angina pectoris aspect, also has antitumor action simultaneously, clinical for late period metastatic cancer certain curative effect is arranged.

Just because of Co-Q10 has so numerous good effect and curative effects, there is diversified coenzyme Q10 capsule on sale on the market at present.What a kind of soft capsule employing was wherein arranged is that Co-Q10, natural VE and rice bran oil mix for three kinds, has alleviating physical fatigue, the health care of enhance immunity power.But because costing an arm and a leg of vitamin E causes product cost obviously to improve after the interpolation; In addition, the antioxygenic property of vitamin E is not very outstanding, causes this soft capsule product to have certain shortcoming yet.

Summary of the invention

To the problems referred to above, the object of the present invention is to provide the anti-oxidant coenzyme Q10 capsule of a kind of rosemary,, the raw material of use all is pure naturals, and it is that the cardiopathic best nutritional of control is plain, and especially the curative effect spy is good in unable etc. the treatment of heart failure, heart.

For achieving the above object; Technical scheme proposed by the invention is: the anti-oxidant coenzyme Q10 capsule of a kind of rosemary; Form by capsule shells and content; It is characterized in that: described content is made up of according to mass ratio following raw material, rosemary antioxidant: Co-Q10: rice bran oil=2-5:3-6:30-80.

Further, described capsule shells is the soft capsule material of commercially available edible.

A kind of rosemary, according to the invention is anti-oxidant coenzyme Q10 capsule preparation method may further comprise the steps:

Step 1: add rosemary antioxidant, Co-Q10 and rice bran oil in the container, stir, get content;

Step 2: adopt the pressing preparation, wrap into content wherein, get the anti-oxidant coenzyme Q10 capsule of rosemary, with capsule shells.

Further, in step 1, described mixing time is 15-20min.

The anti-oxidant coenzyme Q10 capsule of a kind of rosemary, of the present invention has following outstanding advantage:

1) adopt antioxygenic property obviously to be superior to vitamin E and low-cost rosemary antioxidant for adding raw material, not only reduced product cost, also obtained good antioxidant effect simultaneously, be strong anti-oxidant, to the effect extra-heavy of delaying aging;

2) rosemary antioxidant and Co-Q10 have excellent synergy, have improved and enlarged the health care and the sphere of action of Co-Q10;

3) can effectively treat heart disease, hypertension, effective in cure to patient's Zhuo that heart enlarges, cardio-pulmonary function is bad;

4) ability enhance immunity system eliminates the germ in the intrusive body, and anti-curing cancers, chronic infection, beads germ and HIV are benefited;

5) can effectively prevent obesity, multiple sclerosis, periodontitis and diabetes etc.

The specific embodiment

Below in conjunction with specific embodiment, the present invention is further specified.

Embodiment 1

Rosemary antioxidant, Co-Q10 and rice bran oil are added in the container, stir 15-20min, get content; The preparation of employing pressing wraps into content wherein with capsule shells, gets the anti-oxidant coenzyme Q10 capsule of rosemary.Each raw material is counted rosemary antioxidant 30mg by quality, Co-Q10 30mg, rice bran oil 400mg.

Embodiment 2

Rosemary antioxidant, Co-Q10 and rice bran oil are added in the container, stir 15-20min, get content; The preparation of employing pressing wraps into content wherein with capsule shells, gets the anti-oxidant coenzyme Q10 capsule of rosemary.Each raw material is counted rosemary antioxidant 20mg by quality, Co-Q10 40mg, rice bran oil 300mg.

Embodiment 3

Rosemary antioxidant, Co-Q10 and rice bran oil are added in the container, stir 15-20min, get content; The preparation of employing pressing wraps into content wherein with capsule shells, gets the anti-oxidant coenzyme Q10 capsule of rosemary.Each raw material is counted rosemary antioxidant 40mg by quality, Co-Q10 50mg, rice bran oil 600mg.

Embodiment 4

Rosemary antioxidant, Co-Q10 and rice bran oil are added in the container, stir 15-20min, get content; The preparation of employing pressing wraps into content wherein with capsule shells, gets the anti-oxidant coenzyme Q10 capsule of rosemary.Each raw material is counted rosemary antioxidant 50mg by quality, Co-Q10 60mg, rice bran oil 800mg.

Embodiment 5

Rosemary antioxidant, Co-Q10 and rice bran oil are added in the container, stir 15-20min, get content; The preparation of employing pressing wraps into content wherein with capsule shells, gets the anti-oxidant coenzyme Q10 capsule of rosemary.Each raw material is counted rosemary antioxidant 30mg by quality, Co-Q10 60mg, rice bran oil 700mg.

Embodiment 6

Rosemary antioxidant, Co-Q10 and rice bran oil are added in the container, stir 15-20min, get content; The preparation of employing pressing wraps into content wherein with capsule shells, gets the anti-oxidant coenzyme Q10 capsule of rosemary.Each raw material is counted rosemary antioxidant 50mg by quality, Co-Q10 30mg, rice bran oil 600mg.

Embodiment 7: the zoopery interpretation of result

Adopt the anti-oxidant coenzyme Q10 capsule of rosemary, of the present invention also to carry out zoopery; Use small white mouse to be experimental subjects; To normal feeding, add and feed Co-Q10, add the testing result of feeding commercially available vitamin E coenzyme Q10 capsule and the anti-oxidant coenzyme Q10 capsule of rosemary, and compare; Specifically be small white mouse to be added fed 5 days; Every day, feeding Co-Q10 amount was the 20mg/Kg body weight, and the content, atpase activity and the radical damage product that detect myocardial mitochondria combination Co-Q10 simultaneously are the growing amount of lipid peroxidation product MDA, concrete outcome such as following table:

Experimental result shows that the feeding Co-Q10 can obviously improve the combination content of Co-Q10 in the small white mouse mitochondria, makes ATP thereby more help mitochondria, and therefore detecting the ATP synthase activity too has significant raising.Also explanation of experiment; Replenish the anti-oxidant coenzyme Q10 capsule of rosemary; Co-Q10 in the small white mouse mitochondria combines content and ATP synthase activity all than additional commercially available vitamin E coenzyme Q10 capsule significant raising to be arranged; This explanation is because the adding of rosemary antioxidant more helps Co-Q10 to be absorbed by animal.The supplemented with exogenous Co-Q10 can make animal mitochondria receive the damage of oxygen radical, the side effect of Here it is Co-Q10, and the degree of its damage can be judged according to the growing amount of the fat peroxidating product MDA that produces because of damage.According to detection to radical damage product MDA growing amount; We also are easy to and can find; Replenish anti-oxidant coenzyme Q10 capsule of rosemary, and commercially available vitamin E coenzyme Q10 capsule, all can alleviate additional caused radical damage greatly, but the effect of the anti-oxidant coenzyme Q10 capsule of rosemary, still significantly is superior to commercially available vitamin E coenzyme Q10 capsule owing to Co-Q10; Can cause radical damage hardly; Its basic reason should be because rosemary antioxidant has the oxidation resistance more much better than than vitamin E, can effectively remove the oxygen radical in the body, avoids taking in the external source Co-Q10 and the radical damage that brings.

Although specifically show and introduced the present invention in conjunction with preferred embodiment; But the those skilled in the art should be understood that; In the spirit and scope of the present invention that do not break away from appended claims and limited; In form with on the details the present invention is made various variations, be protection scope of the present invention.

Claims (4)

1. the anti-oxidant coenzyme Q10 capsule of rosemary, is made up of capsule shells and content, and it is characterized in that: described content is made up of according to weight ratio following raw material: rosemary antioxidant: Co-Q10: rice bran oil=2-5:3-6:30-80.

2. the anti-oxidant coenzyme Q10 capsule of a kind of rosemary, according to claim 1 is characterized in that: described capsule shells is the soft capsule material of commercially available edible.

3. anti-oxidant coenzyme Q10 capsule preparation method of rosemary, is characterized in that: adopt claim 1 or 2 described capsule shells and content raw material composition, further comprising the steps of:

Step 1: add rosemary antioxidant, Co-Q10 and rice bran oil in the container, stir, get content;

Step 2: adopt the pressing preparation, wrap into content wherein, get the anti-oxidant coenzyme Q10 capsule of rosemary, with capsule shells.

4. the anti-oxidant coenzyme Q10 capsule preparation method of a kind of rosemary, according to claim 3 is characterized in that: in step 1, described mixing time is 15-20min.