CN101766274B - Antioxidant functional food composition containing bamboo-leaves flavones - Google Patents
Antioxidant functional food composition containing bamboo-leaves flavones Download PDFInfo
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Abstract
The invention discloses an antioxidant functional food composition containing bamboo-leaves flavones, consisting of the following ingredients: bamboo-leaves flavones, antioxidant vitamin C groupe and antioxidant vitamin E groupe, wherein the weight ratio of bamboo-leaves flavones: antioxidant vitamin C groupe and antioxidant vitamin E groupe is equal to 2-20:1. The antioxidant vitamin C groupe is at least one of vitamin C, vitamin C salt and vitamin C esters, and the antioxidant vitamin E groupe is at least one of vitamin E, vitamin E salt and vitamin E esters. The composition has multiple effects of free radical resistance, oxidation resistance, antiatheroscloresis, pressure reduction, heart health protection and the like.
Description
Technical field
The invention belongs to functional food and healthy food field; The composition of specifically a kind of bamboo-leaves flavones and antioxidant vitamins and derivative thereof has remarkable Green Tea Extract, anti-oxidant, lipopenicillinase, step-down and heart health effect.
Background technology
Human body is an aerobe, is not coming into contacts with oxygen all the time.What aging course was played important progradation is various active oxygen radicals, and nearly all human diseases can both find the relation with free radical.The power of human body self anti-oxidative defense system ability depends on the meals composition to a great extent.Food is considered in following four kinds of main diseases, play an important role: angiocardiopathy, cancer, hypertension and obesity.Over nearly 30 years, a large amount of research proposals: the pathogenic factor of some unaccountable angiocardiopathies possibly be owing to the insufficiency of intake that has the micronutrient of antioxidation activity in the meals, like V
E, V
C, carotenoid and flavone compound etc.Thereby the natural inhibitor of supplemented with exogenous property, be to delay or reduce the human body oxidative damage, resist one of old and feeble important channel.
In China, include the control of cardiovascular and cerebrovascular disease in public health service.Hyperlipidemia is a kind of common clinical, in artery sclerosis, coronary heart disease, pathogenic mechanism of obesity, plays an important role.Recent two decades comes, and in use medicine is prevented and treated the hyperlipidemia aspect and done number of research projects, finds that existing more than 60 kind of Chinese herbal medicine has therapeutic action to hyperlipidemia.Modern study confirms that the oxidation of the cholesterol of free radical intermediary is to cause atherosclerotic committed step.LDL-C in the arterial wall (LDL-c) content is proportional to LDL-c concentration in the blood plasma; The dysbolism of LDL-c can make LDL-c rising in the blood plasma, and LDL-c raises then can invade arterial wall, again because of containing a large amount of cholesterol among the LDL-c; And protein phosphatide is less relatively; So extremely unstable, in ductus arteriosus wall, make cholesterinosis, cause atherosclerotic.Research shows that the various chemical modifications of LDL-c are to cause the pathogenetic main cause of lipoprotein striped in the blood plasma.This chemical modification meeting receives the inhibition of anti-oxidant in the blood plasma; Therefore, the oxidative modification that suppresses LDL-c effectively has great importance to preventing and treating atherosclerotic.
Bamboo-leaves flavones (bamboo leafflavonoids; BLF) be China's novel plant flavones preparation initiative, that have independent intellectual property right; Be derived from the phenol property position of medicine-food two-purpose " lophatherum gracile "; Main active is to be phenoloid (Zhang Ying etc., one of bamboo-leaves flavones latest Progress---the existence and the effect thereof of phenolic acid compound in the bamboo-leaves flavones preparation, the Food Additives Used in China of representative with flavone glycoside (Lutonaretin, orientoside, Saponaretin, Vitexina etc.) and phenolic acid (p-Coumaric Acid, chlorogenic acid, forulic acid and caffeic acid); 2009,4:46-53).The health food ZHUKANGNING (regulating blood fat, enhance immunity) that with the bamboo-leaves flavones is raw material has gone on the market for many years, obtains consumer's extensive favor.With leaf of bamboo phenol property position is that " AOB (AOB) " of characteristic component also used as food additives by Chinese Government approval in 2004.Bamboo-leaves flavones has multi-biological and learns effect, and outstanding behaviours is at the physiology and the pharmacologically active of cardiovascular and cerebrovascular, like Green Tea Extract, anti-oxidant; Anti-anoxic, antifatigue; Reducing blood lipid, increases myocardial contractive power, improves myocardial ischemia and dwindles the heart stalk scope coronary artery dilating blood vessel; Reduce the platelet aggregation degree, suppress blood coagulation and thrombosis, anti-cerebral ischemia etc.A large amount of researchs also show, bamboo-leaves flavones not only has good resistant activity oxygen radical and an anti peroxidation of lipid ability external, and; Can significantly promote the vigor of endogenous antioxidase system (SOD, GSH-Px, Cat) in animal body, be a kind of biological anti-oxidant of brilliance, and nontoxic, have no side effect; Can take for a long time; The ideal that is human body supplemented with exogenous property anti-oxidant is selected (Lu Baiyi, Zhang Ying, Wu Xiaoqin, the anti-oxidant and cardiovascular and cerebrovascular pharmacology activity research progress of bamboo-leaves flavones, chemistry of forest product and industry; 2005,23 (3): 120-124).
Cassia seed is the dry mature seed of legume Cassia tora Cassia obtusfolia L. or little Cassia tora C.toraL., is clinical conventional Chinese medicine, also is the natural plants of the medicine-food two-purpose of China Ministry of Public Health promulgation.Beginning is stated from Shennong's Herbal, and nature and flavor are sweet, bitter, salty, are slightly cold; Return liver, kidney, large intestine channel; Have and clear liver and improve vision, the effect that relaxes bowel.That modern study proof cassia seed has is antibacterial, hypotensive, reducing blood lipid, protect the liver, pharmacological action such as diuresis.Cassia seed contains number of chemical compositions such as the awake class of a species of orchid, naphthalene derivatives, carbohydrate, lipid, protein and trace element.Food, health food and natural medicine field in lipopenicillinase, step-down obtained using widely in recent years.
Red colouring agent for food, also used as a Chinese medicine (Red Kojic Rice) is that monascus is bred the goods on rice or other cereal crops, can make medicinal and food color, and its medicinal function is early on the books in Compendium of Material Medica and " Chinese medicine voluminous dictionary ".Japan rattan chapter professor far away in 1979 has caused whole world scientist's concern after from the monascus culture, isolating a kind of physiological activator that is Monacolin K (monacolin K).Functional red yeast rice is exactly a kind of abundant bioactive enzyme and several physiological active substances of containing; The metabolite of red colouring agent for food, also used as a Chinese medicine bacterium such as Monacolin-K, ergosterol, GABA, natural phytohormone; Have high nutrition, health care, medical value; Health food without any side effects, natural, safe and effective, pharmaceutical raw material.The mechanism of red colouring agent for food, also used as a Chinese medicine reducing blood lipid can be regarded as: apolipoprotein matter is the part of lipoprotein, and when apolipoprotein matter APO-AI and APO-B horizontal abnormality, the key enzyme of fat metabolic process just loses activity, thereby causes disorders of lipid metabolism.Experiment shows that the Monacolin compounds can reduce the APO-AI level of hyperlipidemia patient, and its APO-B level that raises is corrected disorders of lipid metabolism, thereby plays the effect of regulating blood fat.
(Tea Polyphenol is the come out complex of polyphenol compound of separation and Extraction from natural plants tealeaves TP) to Tea Polyphenols, contains four big materials such as catechin, flavones and flavonols, anthocyan, phenolic acid and depside.A large amount of researchs show; Tea Polyphenols has plurality of health care functions and pharmacodynamics effect, as antibiotic, antiviral, antitoxin, anti-cancer, anticancer, anti-sudden change, reducing blood lipid, hypotensive, hypoglycemic, prevent artery sclerosis and thrombosis, protection liver, anti-ageing, anti-carious tooth, antiallergy etc.In recent years research shows that Tea Polyphenols is the potent inhibitor of LDL-c oxidation, can suppress the oxidative modification of LDL-c effectively, thus the generation of prevention pulse atherosclerosis.Many researchs confirm that Tea Polyphenols also has anticoagulant, and short fibrinolytic and the effect of inhibition platelet aggregation more than must have positive effect to atherosclerotic prevention.
(Ascorbyl palmitate AP) by palmitate and the esterification of L-ascorbic acid and get, belongs to one of the strongest anti-oxidant, and is a kind of auxotype anti-oxidant vitamin(e) C palmitate.Its hydrolysate L-ascorbic acid and palmitate all are natural products, belong to green product.AP has obtained the international food and agricultural organization and the World Health Organization (FAO/WHO) approval in the world and has used since coming out, and every day, intake was the 1.25g/kg body weight.In the U.S., assert it is safe anti-oxidant, its addition is restriction not.At food additives legislative bodies of European Community approved as food antioxidant.In China, AP is unique anti-oxidant that allows to add in the baby food.
(d-α-Tocopheryl acid succinate VEs) is a kind of derivative of VE (alpha-tocopherol) to VE-succinate.In the VE series products, VEs has plurality of advantages, as: biologically active is high, stability is high than VE, has unique anticancer health-care function, can suppress the hyperplasia of kinds of tumor cells, promotes tumour cell to degenerate.In all members of group vitamins, anticancer effect is apparent that alpha-tocopherol and tocopherol succinate most, and VEs can not destroy normal cell, and Normocellular growth is not had influence, thereby as safe as a house.Become the most general raw material of the medicine of VE class healthy food and prevention and treatment tumour at present.
Do not see at present research that the functional food composition that contains bamboo-leaves flavones and antioxidant vitamins and derivative thereof is arranged and products thereof as yet.
Summary of the invention
The technical problem that the present invention will solve provides the functional food composition of a kind of bamboo-leaves flavones and antioxidant vitamins and derivative thereof, has multi-efficiencies such as Green Tea Extract, anti-oxidant, reducing blood lipid, step-down and heart health.
In order to solve the problems of the technologies described above; The present invention provides a kind of antioxidant functional food composition that contains bamboo-leaves flavones; Said composition is grouped into by following one-tenth: bamboo-leaves flavones, antioxidant vitamins C class and antioxidant vitamins E class, bamboo-leaves flavones: weight ratio=2～20 of (antioxidant vitamins C class+antioxidant vitamins E class): 1.
As the improvement that contains the antioxidant functional food composition of bamboo-leaves flavones of the present invention: the weight ratio of antioxidant vitamins C class and antioxidant vitamins E class is 1～6: 1.
As the further improvement that contains the antioxidant functional food composition of bamboo-leaves flavones of the present invention: antioxidant vitamins C class is at least a in vitamin C, vitamin C salt and the vitamin C ester class, and antioxidant vitamins E class is at least a in vitamin E, vitamin E salt and the vitamin-e ester class.
As the further improvement that contains the antioxidant functional food composition of bamboo-leaves flavones of the present invention: the vitamin C ester class is a vitamin(e) C palmitate, and the vitamin-e ester class is VE-succinate or Vitwas E.
The antioxidant functional food composition that contains bamboo-leaves flavones of the present invention can be various ways such as capsule, tablet, granule or pulvis.
The anti-oxidative defense system of known human body is the synergistic result of multiple oxidation-resistant active ingredient (comprising enzyme and non-enzyme compound, hydrophily, lipophilicity and middle polarity compound etc.).Research shows that bamboo-leaves flavones is the flavone sugar glycoside material of medium polarity bigger than normal, when itself and hydrophilic vitamin C and lipophilic vitamin E organic assembling, can form stable, " anti-oxidant Golden Triangle " efficiently, has remarkable role in synergy.Simultaneously; When bamboo-leaves flavones uses separately; The defective that the ubiquity bioavilability is not high, and the ester derivative of vitamin C and vitamin E has the molecular configuration of typical emulsifying agent, so when the ester derivative of vitamin C and vitamin E exists; Can promote bamboo-leaves flavones absorption in vivo and conversion greatly, improve bioavilability.Prescription the monarch and his subjects of the present invention are auxilliary mutually, bring out the best in each other, and gentle flat benefit, suitable crowd is extensive, and suitable especially the elderly is often edible.
In sum, the present invention compared with prior art, its advantage is: bamboo-leaves flavones and vitamin C and vitamin E and derivative thereof are composite, have formed stable, " anti-oxidant Golden Triangle " efficiently, show remarkable role in synergy.And because the existence of antioxidant vitamins ester derivative, improved the bioavilability of bamboo-leaves flavones greatly, made that in vivo Green Tea Extract of product, anti-oxidant and functions such as lipopenicillinase, step-down are strengthened.Antioxidant functional food composition of the present invention has that production technology is simple, constant product quality, function factor is clear, health-care efficacy is outstanding, bioavilability is high, taking dose is little, edible safety, advantage such as have no side effect.
The specific embodiment
Compositions all among the present invention all can obtain through commercial mode, are the food grade commercial goods; For example bamboo-leaves flavones can be selected the bamboo-leaves flavones (BLF-d24) of Hangzhou Youmeite Technology Co., Ltd. for use, and it includes general flavone >=24%, Lutonaretin >=2%, p-Coumaric Acid >=0.5%.
Embodiment 1, a kind of antioxidant functional food composition, said composition is made up of bamboo-leaves flavones, vitamin(e) C palmitate and Vitwas E.
Above-mentioned antioxidant functional food composition is processed compound, and this compound is made up of the prescription of following weight content:
Prescription is formed percentage by weight
Bamboo-leaves flavones 60%
Cassia seed (Powdered) 30%
Vitamin(e) C palmitate 6%
Vitwas E 4%
Its preparation method is following:
Commercial cassia seed is fried, pulverized through conventional roasting, sieve (80～100 order), thus obtain pulverous cassia seed; Mix mutually with the bamboo-leaves flavones that is powder, vitamin(e) C palmitate and Vitwas E according to above-mentioned weight proportion then.Capsule manufacture technology can according to routine becomes hard shell capsules.Every capsules content net weight 250mg, a day recommendation taking dose is 2～4.
Composition principle is following: with the bamboo-leaves flavones is monarch drug in a prescription, is ministerial drug with the cassia seed, with Vitwas E and vitamin(e) C palmitate as the function auxiliary element.The biological effectiveness outstanding behaviours of bamboo-leaves flavones exists: anti-oxidant, Green Tea Extract, antifatigue, accent fat, expand hat and protection cardiovascular and cerebrovascular; Cassia seed have good reducing blood lipid, hypotensive, clear liver and improve vision, relax bowel, diuresis and bacteria resistance function; Vitamin(e) C palmitate is a kind of auxotype anti-oxidant, and is composite with Flavonoid substances, has strong synergistic effect; Vitwas E is V
EActive stronger a kind of in the derivative, have unique health care.The combination of above component has formed stable " anti-oxidant Golden Triangle ", and has shown remarkable role in synergy.Simultaneously, because the emulsifying capacity of vitamin(e) C palmitate and Vitwas E has improved the bioavilability of bamboo-leaves flavones in human body greatly.
The contrast experiment 1:
Contemporary with 10% maltodextrin for vitamin(e) C palmitate and Vitwas E, process the capsule of same specification weight, as alternative capsule 1 (control group 1);
Maltodextrin with 4% replaces Vitwas E, processes the capsule of same specification weight, as alternative capsule 2 (control group 2).
Vitamin(e) C palmitate with 4% replaces Vitwas E, processes the capsule of same specification weight, as alternative capsule 3 (control group 3).
One, external antioxygenic activity evaluation
In order to prove the synergistic function of bamboo-leaves flavones and vitamin(e) C palmitate and Vitwas E in the present invention; With the foregoing description 1 gained capsule is test group; Substituting capsule 3 with above-mentioned alternative capsule 1-is control group, carries out the test and evaluation of antioxidation in vitro ability.
Wait respectively that to measure capsule 's content an amount of; With 30% (volume ratio) dissolve with ethanol solution, the ultrasonic wave hydrotropy filters the back is settled to sample with above-mentioned ethanolic solution general flavone content (aluminum nitrate-natrium nitrosum colorimetric method; In rutin) be 0.1mg/mL, measure it respectively and remove DPPH
.And ABTS
+Activity and TAC (rat blood serum is available from Beijing ancient cooking vessel state bio tech ltd; The TAC kit is that the bio tech ltd product is built up in Nanjing), the result sees table 1.
Table 1
| Group | DPPH inhibiting rate (%) (adding the 0.2mL sample) | ABTS +Inhibiting rate (%) (adding the 0.1mL sample) | TAC (units per ml serum) (adding the 0.1mL sample) |
| Control group 1 | 34.73±0.98 | 29.02±0.61 | 18.19±1.55 |
| Control group 2 | 45.13±0.84 ** | 49.76±0.69 ** | 21.34±1.32 |
| Control group 3 | 47.22±0.99 ** | 54.34±0.87 ** | 22.57±1.11 |
| Test group (the present invention) | 53.32±0.87 *** | 83.46±0.75 *** | 25.19±1.47 * |
Compare with contrast:
*P＜0.05;
*P＜0.01;
* *P＜0.001.
Can see from above test data; The compositions table of bamboo-leaves flavones and vitamin(e) C palmitate and Vitwas E reveals extremely strong collaborative antioxidation, and effect significantly is superior to using separately the combination of bamboo-leaves flavones and bamboo-leaves flavones and vitamin(e) C palmitate.
The contrast experiment 2: human feeding trial
Select the 81 routine lipid metabolisms unusual volunteer (serum cholesterol >=5.98mmol/L of age between 40～60 years old; Triglyceride >=2.2mmol/L) carry out test-meal to test; Be divided into 2 groups at random, take the test group that is of embodiment 1 capsule, take the control group that is that substitutes capsule 1; Dose is: 4 of every days, each 2 sooner or later; Take the content that cholesterol in serum (TC), triglyceride (TG) and HDL-C (HDL-c) are measured in 12 all backs continuously.Actual recovered result of laboratory test 64 examples, table 2 is seen in data statistics.
Table 2
The result of human feeding trial proves functional food of the present invention, and it transfers the fat effect significantly to be superior to control group, and the composition of bamboo-leaves flavones and vitamin(e) C palmitate and Vitwas E has extremely strong correction effect to the human body abnormalities of sugar/lipid metabolism.
In addition, the capsule of embodiment 1 gained has been collected 150 routine representational cases altogether through the test of crowd widely of more than half a year (in March, 2009～December), and the statistics classification of feedback effects is like table 3.
Table 3
Above-mentioned statistics proves: the present invention also shows significant anti-effect that cures cold and heart health effect (as to the control of premature beat, heart murmur, tachycardia etc. etc.) when bringing into play efficiently Green Tea Extract, anti-oxidant, lipopenicillinase, hypotensive effect.
Embodiment 2, a kind of antioxidant functional food composition, said composition is made up of bamboo-leaves flavones, vitamin C, vitamin(e) C palmitate and Vitwas E.
Above-mentioned antioxidant functional food composition is processed compound, and this compound is made up of the prescription of following weight content:
Prescription is formed percentage by weight
Bamboo-leaves flavones 30%
Vitamin C 2%
Vitamin(e) C palmitate 0.5%
Vitwas E 0.5%
Xylitol 27%
Polydextrose 40%
The preparation method is following:
The vitamin C of powdered, vitamin(e) C palmitate, Vitwas E mix with bamboo-leaves flavones, xylitol and polydextrose mutually; Process pulvis through conventional technology, every bag content net weight 5g, a day recommendation taking dose is bag every day 1, brews the back drink-service with warm boiling water.
When the characteristics of this prescription are the collaborative antioxidation of bamboo-leaves flavones and vitamin C and vitamin E, play whole intestines function with polydextrose as prebiotics, xylitol then plays liver protection effect when appropriate sweet taste is provided.This prescription particularly is fit to have the elderly of symptoms such as constipation, hyperglycaemia to take.
The contrast experiment 3:
Contemporary with the maltodextrin of 3% (weight ratio) for vitamin C, vitamin(e) C palmitate and Vitwas E, process the pulvis of same specification weight, as alternative pulvis 1 (control group 1); Vitamin(e) C palmitate with 0.5% (weight ratio) replaces Vitwas E, as alternative pulvis 2 (control group 2); Contemporary with the Vitwas E of 2.5% (weight ratio) for vitamin C and vitamin(e) C palmitate, as alternative pulvis 3 (control group 3); With embodiment 2 gained pulvis is test group, and substituting pulvis 3 with above-mentioned alternative pulvis 1-is control group, carries out the test and evaluation of antioxidation in vitro ability.Experimental technique is with contrast experiment 1, and the result sees table 4.
Table 4
| Group | DPPH inhibiting rate (%) (adding the 0.2mL sample) | ABTS +Inhibiting rate (%) (adding the 0.1mL sample) | TAC (units per ml serum) (adding the 0.1mL sample) |
| Control group 1 | 34.73±0.98 | 29.02±0.61 | 18.19±1.55 |
| Control group 2 | 39.25±0.78 * | 34.15±0.99 * | 21.04±1.12 |
| Control group 3 | 38.21±0.65 * | 33.72±0.77 * | 20.45±0.98 |
| Test group (the present invention) | 48.43±1.32 ** | 39.57±0.94 ** | 23.23±0.89 * |
Compare with contrast:
*P＜0.05;
*P＜0.01.
Can see from above test data; The compositions table of bamboo-leaves flavones and vitamin C, vitamin(e) C palmitate and Vitwas E reveals significant collaborative antioxidation, effect be superior to using separately bamboo-leaves flavones and bamboo-leaves flavones respectively with two two compsns of vitamin(e) C palmitate and Vitwas E.
The crowd who takes above-mentioned alternative pulvis 1 with the long period (about 1 year, every day 1, bag was taken during breakfast) withdraws above-mentioned alternative pulvis after 1 one weeks as subjects, changes the pulvis of clothes embodiment 2 gained, and every day 1, bag was taken during breakfast; 4 week backs are collected altogether and are returned feedback case 15 examples, and wherein 11 example reflection effects obviously are superior to substituting pulvis 1, mainly show antifatigue, improve sleep and relax bowel etc.; But 4 routine sensory differences are not obvious.
Embodiment 3, a kind of antioxidant functional food composition, said composition is made up of bamboo-leaves flavones, vitamin(e) C palmitate and Vitwas E.
Above-mentioned antioxidant functional food composition is processed compound, and this compound is made up of the prescription of following weight content:
Prescription is formed percentage by weight (%)
Bamboo-leaves flavones 10%
Vitamin(e) C palmitate 3%
Vitwas E 2%
Lactose 25%
Polydextrose 60%
The preparation method is following:
The vitamin(e) C palmitate of powdered and Vitwas E after bamboo-leaves flavones, lactose, polydextrose mix, are processed granule according to common process; Every bag of content net weight 5g; Recommending dose day is 1 bag, brews the back drink-service with warm boiling water, also dissolves in milk or the soya-bean milk with obeying.
The characteristics of this prescription are with the collaborative antioxidation of bamboo-leaves flavones and vitamin C ester and vitamin-e ester the time; With polydextrose as prebiotics; As sweetener, the children that particularly are fit to not like ingest capsule and tablet take with lactose, when breakfast with milk or soya-bean milk is same obeys.Children and population of adolescent that, vegetables too refining to food and fruit intake are not enough are the most effective.
The contrast experiment 4:
More contemporary for vitamin(e) C palmitate and Vitwas E with identical weight than the maltodextrin of (5%), process the granule of same specification weight, as the substitute particles agent.With the foregoing description 3 gained granules is test group, is control group with above-mentioned substitute particles agent, carries out the test and evaluation of antioxidation in vitro ability.Experimental technique is with contrast experiment 1, and the result sees table 5.
Table 5
| Group | DPPH inhibiting rate (%) (adding the 0.2mL sample) | ABTS +Inhibiting rate (%) (adding the 0.1mL sample) | TAC (units per ml serum) (adding the 0.1mL sample) |
| Control group | 34.73±0.98 | 29.02±0.61 | 18.19±1.55 |
| Test group (the present invention) | 81.32±0.87 *** | 73.26±2.75 *** | 45.19±2.37 *** |
Compare with contrast:
* *P＜0.001.
Can see that from above test data the compositions table of bamboo-leaves flavones vitamin(e) C palmitate and Vitwas E reveals extremely strong collaborative antioxidation, effect significantly is superior to using separately bamboo-leaves flavones.
With between the student of Senior Two and Senior Three (age 15-17 year) as the test crowd, 1 bag of ingesting during breakfast every day reclaims 18 parts of effective questionnaires altogether.After 2 weeks, the above reflection of 2/3rds people, take the granule of embodiment 3 gained after, sense of fatigue clearheaded, quick-minded, energetic, long-time, that high strength study produces obviously alleviates.
Embodiment 4, a kind of antioxidant functional food composition, said composition is made up of bamboo-leaves flavones, vitamin(e) C palmitate and VE-succinate.
Above-mentioned antioxidant functional food composition is processed compound, and this compound is made up of the prescription of following weight content:
Prescription is formed percentage by weight
Bamboo-leaves flavones 40%
Functional red yeast rice 5%
Vitamin(e) C palmitate 1%
VE-succinate 1%
Polydextrose 50%
Dolomol 3%
The preparation method is following: with the functional red yeast rice of powdered and vitamin(e) C palmitate, VE-succinate, and bamboo-leaves flavones, polydextrose, dolomol mix the back and process tablet according to common process.
The principle of this prescription is to be the major function composition with Herba Lophatheri extract (bamboo-leaves flavones), as function auxiliary element and Synergistic composition, has the function of remarkable accent fat, lipopenicillinase and heart health with functional red yeast rice and antioxidant vitamins ester.And, adopt the plastic-aluminum pressing plate with the form of plain sheet, and easy to carry, particularly be fit to the white collar crowd of frequent out of town trip.
The contrast experiment 5:
With maltodextrin replacement vitamin(e) C palmitate and the VE-succinate of identical weight, process the tablet of same specification weight, as alternative tablet than (2%).With the foregoing description 4 gained tablets is test group, is control group with above-mentioned alternative tablet, carries out the test and evaluation of antioxidation in vitro ability.Experimental technique is with contrast experiment 1, and the result sees table 6.
Table 6
| Group | DPPH inhibiting rate (%) (adding the 0.2mL sample) | ABTS +Inhibiting rate (%) (adding the 0.1mL sample) | TAC (units per ml serum) (adding the 0.1mL sample) |
| Control group | 34.73±0.98 | 29.02±0.61 | 18.19±1.55 |
| Test group (the present invention) | 38.12±0.89 * | 35±0.65 ** | 22.43±0.98 * |
Compare with contrast:
*P＜0.05;
*P＜0.05.
Can see that from above test data the compositions table of bamboo-leaves flavones and vitamin(e) C palmitate and VE-succinate reveals significant collaborative antioxidation, effect is superior to using separately bamboo-leaves flavones.
At last, it is also to be noted that what more than enumerate only is several specific embodiments of the present invention.Obviously, the invention is not restricted to above embodiment, many distortion can also be arranged.All distortion that those of ordinary skill in the art can directly derive or associate from content disclosed by the invention all should be thought protection scope of the present invention.
Claims (1)
1. antioxidant functional food composition that contains bamboo-leaves flavones; It is characterized in that said composition is grouped into by following one-tenth: bamboo-leaves flavones, antioxidant vitamins C class and antioxidant vitamins E class, said bamboo-leaves flavones: weight ratio=2～20 of (antioxidant vitamins C class+antioxidant vitamins E class): 1; Said antioxidant vitamins C class is a vitamin(e) C palmitate, and antioxidant vitamins E class is VE-succinate or Vitwas E; The weight ratio of said antioxidant vitamins C class and antioxidant vitamins E class is 1～6: 1.
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| CN113143962B (en) * | 2021-05-11 | 2022-08-05 | 四川九章生物科技有限公司 | A pharmaceutical composition for treating hyperlipidemia, and its preparation method |
| CN116211927A (en) * | 2023-04-13 | 2023-06-06 | 梓森科技股份有限公司 | Hypolipidemic composition containing natural lovastatin and application thereof |
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| CN101332167A (en) * | 2008-07-04 | 2008-12-31 | 山东省医药工业研究所 | Use of bamboo leaf flavone in preparing cosmetics and food additives |
| CN101422239A (en) * | 2007-11-02 | 2009-05-06 | 冷雪飞 | Combined partner capable of increasing edible rice, flour nutrition |
| CN101496588A (en) * | 2008-01-29 | 2009-08-05 | 北京康必得药业有限公司 | Chewing tablet for protecting sight |
| CN101611917A (en) * | 2009-07-28 | 2009-12-30 | 孙爱东 | A kind of novel natural food preservative that utilizes bamboo-leaves flavones to produce |
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| CN101422239A (en) * | 2007-11-02 | 2009-05-06 | 冷雪飞 | Combined partner capable of increasing edible rice, flour nutrition |
| CN101496588A (en) * | 2008-01-29 | 2009-08-05 | 北京康必得药业有限公司 | Chewing tablet for protecting sight |
| CN101332167A (en) * | 2008-07-04 | 2008-12-31 | 山东省医药工业研究所 | Use of bamboo leaf flavone in preparing cosmetics and food additives |
| CN101611917A (en) * | 2009-07-28 | 2009-12-30 | 孙爱东 | A kind of novel natural food preservative that utilizes bamboo-leaves flavones to produce |
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