JP2004329047A - Dietary supplement - Google Patents
Dietary supplement Download PDFInfo
- Publication number
- JP2004329047A JP2004329047A JP2003126366A JP2003126366A JP2004329047A JP 2004329047 A JP2004329047 A JP 2004329047A JP 2003126366 A JP2003126366 A JP 2003126366A JP 2003126366 A JP2003126366 A JP 2003126366A JP 2004329047 A JP2004329047 A JP 2004329047A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- dietary supplement
- intake
- effect
- daily intake
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000015872 dietary supplement Nutrition 0.000 title claims abstract description 42
- 239000000284 extract Substances 0.000 claims abstract description 29
- 240000000249 Morus alba Species 0.000 claims abstract description 24
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 24
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 10
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims abstract description 10
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims abstract description 10
- 229940106189 ceramide Drugs 0.000 claims abstract description 10
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims abstract description 10
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000000661 sodium alginate Substances 0.000 claims abstract description 10
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 10
- 229940005550 sodium alginate Drugs 0.000 claims abstract description 10
- 241000209140 Triticum Species 0.000 claims abstract description 8
- 235000021307 Triticum Nutrition 0.000 claims abstract description 8
- 241001474374 Blennius Species 0.000 claims abstract description 7
- 239000000843 powder Substances 0.000 claims description 10
- 229920001353 Dextrin Polymers 0.000 claims description 8
- 239000004375 Dextrin Substances 0.000 claims description 8
- 235000019425 dextrin Nutrition 0.000 claims description 8
- 235000019674 grape juice Nutrition 0.000 claims description 8
- 229940087603 grape seed extract Drugs 0.000 claims description 8
- 235000002532 grape seed extract Nutrition 0.000 claims description 8
- 235000012054 meals Nutrition 0.000 claims description 8
- 239000001717 vitis vinifera seed extract Substances 0.000 claims description 8
- 229940032591 grape seed extract 50 mg Drugs 0.000 claims 1
- 239000008280 blood Substances 0.000 abstract description 21
- 210000004369 blood Anatomy 0.000 abstract description 21
- 235000000346 sugar Nutrition 0.000 abstract description 18
- 208000008589 Obesity Diseases 0.000 abstract description 17
- 235000020824 obesity Nutrition 0.000 abstract description 17
- 235000005911 diet Nutrition 0.000 abstract description 12
- 230000037213 diet Effects 0.000 abstract description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 12
- 201000010099 disease Diseases 0.000 abstract description 11
- 239000004615 ingredient Substances 0.000 abstract description 6
- 239000000203 mixture Substances 0.000 abstract description 6
- 230000007423 decrease Effects 0.000 abstract description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 abstract 1
- 235000012333 Vitis X labruscana Nutrition 0.000 abstract 1
- 240000006365 Vitis vinifera Species 0.000 abstract 1
- 235000014787 Vitis vinifera Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 25
- 235000001916 dieting Nutrition 0.000 description 9
- 230000037228 dieting effect Effects 0.000 description 9
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 8
- 210000003491 skin Anatomy 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000003078 antioxidant effect Effects 0.000 description 5
- 230000006378 damage Effects 0.000 description 5
- 230000000968 intestinal effect Effects 0.000 description 5
- 230000003020 moisturizing effect Effects 0.000 description 5
- 235000013824 polyphenols Nutrition 0.000 description 5
- 206010003210 Arteriosclerosis Diseases 0.000 description 4
- 208000011775 arteriosclerosis disease Diseases 0.000 description 4
- 206010012601 diabetes mellitus Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000037406 food intake Effects 0.000 description 4
- 150000008442 polyphenolic compounds Chemical class 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- 239000003613 bile acid Substances 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 3
- 235000013325 dietary fiber Nutrition 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 108010071584 oxidized low density lipoprotein Proteins 0.000 description 3
- 208000019553 vascular disease Diseases 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- JPFCOVZKLAXXOE-XBNSMERZSA-N (3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2r,3r,4r)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-4-yl]-3,4-dihydro-2h-chromene-3,5,7-triol Chemical compound C1=C(O)C(OC)=C(O)C=C1C1[C@H](O)CC(C(O)=CC(O)=C2[C@H]3C4=C(O)C=C(O)C=C4O[C@@H]([C@@H]3O)C=3C=CC(O)=CC=3)=C2O1 JPFCOVZKLAXXOE-XBNSMERZSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 206010009944 Colon cancer Diseases 0.000 description 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 description 2
- 206010013786 Dry skin Diseases 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 108010007622 LDL Lipoproteins Proteins 0.000 description 2
- 229920001991 Proanthocyanidin Polymers 0.000 description 2
- 230000009102 absorption Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 235000019577 caloric intake Nutrition 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 235000020805 dietary restrictions Nutrition 0.000 description 2
- 230000037336 dry skin Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000001596 intra-abdominal fat Anatomy 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 235000020095 red wine Nutrition 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 241000512259 Ascophyllum nodosum Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010008132 Cerebral thrombosis Diseases 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 206010012438 Dermatitis atopic Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 208000022072 Gallbladder Neoplasms Diseases 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 208000035150 Hypercholesterolemia Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020710 Hyperphagia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 208000012659 Joint disease Diseases 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- 102100024295 Maltase-glucoamylase Human genes 0.000 description 1
- 206010049565 Muscle fatigue Diseases 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 241000241413 Propolis Species 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 102000004139 alpha-Amylases Human genes 0.000 description 1
- 108090000637 alpha-Amylases Proteins 0.000 description 1
- 108010028144 alpha-Glucosidases Proteins 0.000 description 1
- 229940024171 alpha-amylase Drugs 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000010208 anthocyanin Nutrition 0.000 description 1
- 239000004410 anthocyanin Substances 0.000 description 1
- 229930002877 anthocyanin Natural products 0.000 description 1
- 150000004636 anthocyanins Chemical class 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000005487 catechin Nutrition 0.000 description 1
- 150000001765 catechin Chemical class 0.000 description 1
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 201000001883 cholelithiasis Diseases 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 229920002770 condensed tannin Polymers 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- HVQAJTFOCKOKIN-UHFFFAOYSA-N flavonol Natural products O1C2=CC=CC=C2C(=O)C(O)=C1C1=CC=CC=C1 HVQAJTFOCKOKIN-UHFFFAOYSA-N 0.000 description 1
- 150000002216 flavonol derivatives Chemical class 0.000 description 1
- 235000011957 flavonols Nutrition 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 201000010175 gallbladder cancer Diseases 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 230000002414 glycolytic effect Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 208000006575 hypertriglyceridemia Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000020845 low-calorie diet Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 235000020830 overeating Nutrition 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 125000004402 polyphenol group Chemical group 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229940069949 propolis Drugs 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 210000004003 subcutaneous fat Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【０００１】
【発明の属する技術分野】
本発明は、栄養補助食品に関し、特に血糖値を下げ、ダイエットに効果がある桑の葉を用いた栄養補助食品に関する。
【０００２】
【従来の技術】
主として桑の葉を用いた栄養補助食品として、桑の葉とアガリスクの抽出物を用いたもの（特許文献１参照。）、桑の葉の抽出液をプロポリス加工したもの（特許文献２参照。）、桑の葉の粉末とカキの粉末を用いたもの（特許文献３参照。）、桑の葉とキトサンを用いたもの（特許文献４参照。）、桑の葉と蚕の糞に酒を含ませた後乾燥して粉末としたもの（特許文献５参照。）、桑の葉と梅肉などを素材としたもの（特許文献６参照。）などが報告されており、そのほか多数の組成物のひとつとして桑の葉を用いたものなどは多数報告されている。
【０００３】
しかしながら、従来の報告には、治療の初期から最終段階まで一貫して用いることができるという視点が欠けており、また、各組成物が有効に働くために１日あたりどのぐらいの量を用いればよいかがあまり明確になっていない。
【０００４】
【特許文献１】
特開２００１−２１３７９６号公報（第２−５頁、第１図）
【特許文献２】
特開２００１−１０３９４３号公報（第２頁）
【特許文献３】
特開２００１−４８７９４号公報（第２−７頁）
【特許文献４】
特開２０００−２８１５８３号公報（第３−４頁）
【特許文献５】
特開２０００−１５７２０６号公報（第２−３頁、第１図）
【特許文献６】
特開平１０−１２７２５３号公報（第３−８頁、第１図）
【０００５】
【発明が解決しようとする課題】
以上述べたように、従来報告されている桑の葉を主要組成とする栄養補助食品には、栄養補助食品摂取の初期段階から最終段階まで一貫して用いることができるという視点が欠けており、また、各組成物が有効に働くためには１日あたりどのぐらいの量を摂取すればよいかがあまり明確になっていなかった。
本発明は、桑の葉抽出物を主成分とした複数の成分を含んだ栄養補助食品で、生活習慣病の予防、血糖値の降下、ダイエット、肥満回避の目的に安全に用いることができ、かつ、その栄養補助食品摂取の初期段階から最終段階まで一貫して利用でき、複数の成分がそれぞれ単体で用いた場合よりも有効に働き、口当たりがよくて摂取に無理がなく、かつ含まれる各成分が充分な効果を生むに必要な１日の摂取量と各組成の含有比率とが明確な栄養補助食品の提案を課題とする。
【０００６】
【課題を解決するための手段】
上記課題を解決するため、本発明の栄養補助食品は、桑の葉抽出物と、ぶどう種子抽出物と、セラミド含有小麦抽出物と、アルギン酸ナトリウム含有海藻抽出物とを有して構成されることを特徴とする。
これにより、生活習慣病の予防、血糖値の降下、ダイエット、肥満回避の目的で、栄養補助食品摂取の初期段階から最終段階まで一貫して用いることができ、健康を害することなく無理なくダイエットを行うことができる栄養補助食品を実現することができる。
【０００７】
また、本発明の栄養補助食品は、ぶどう果汁末と、デキストリンとをさらに含むことを特徴とする。
これにより、口当たりがよく無理なく継続した摂取が可能な栄養補助食品を実現することができる。
【０００８】
また、本発明の栄養補助食品は、１日摂取量４．５ｇ〜１０ｇ中に桑の葉抽出物９００ｍｇ〜２０００ｍｇ、ぶどう種子抽出物５０ｍｇ〜２００ｍｇ、セラミド含有小麦抽出物１５ｍｇ〜３５ｍｇ、アルギン酸ナトリウム含有海藻抽出物５０ｍｇ〜２５０ｍｇが含まれていることを特徴とする。
これにより、各成分がそれぞれ有効に働くとともに、かつ各成分が単体で用いた場合よりも有効に働く生活習慣病の予防、血糖値の降下、ダイエット、肥満回避などに有効な栄養補助食品を実現することができる。
【０００９】
また、本発明の栄養補助食品は、１日摂取量４．５ｇ〜１０ｇ中にぶどう果汁末５０ｍｇ〜５００ｍｇと、デキストリン適当量とをさらに含むことを特徴とする。
これにより、口当たりがよく無理なく継続した摂取が可能な栄養補助食品で、各成分の摂取量の配合比のよいものを実現することができる。
【００１０】
さらに、本発明の栄養補助食品は、１日摂取量４．５ｇ〜１０ｇを３回分〜５回分に分けて朝、昼、夕の各食事直前または食事中か間食を取った際に摂取するようにすることを特徴とする。
これにより、本発明の栄養補助食品の各組成が無理なく摂取、吸収され、その都度、糖の分解を抑制して血糖値を降下させるなど、その効果が大きくなる。
【００１１】
【発明の実施の形態】
近年、日本人にも肥満が多くなってきているのは、食生活の欧米化（飽和脂肪酸の摂取量の増加）、過食（摂取カロリーの増加）、運動不足（消費カロリーの不足）が原因と考えられる。
肥満は脂肪がどこに蓄積されているかによって内蔵脂肪型肥満と皮下脂肪型肥満に区別される。内蔵脂肪型肥満は内臓に脂肪が蓄積されたもので、このような肥満の人は、かつては成人病として考えられていた生活習慣病になりやすいため、病的肥満と言われている。生活習慣病の中でも特に多いのが、血液血管系疾患と糖尿病である。血液血管系疾患では高脂血症（高コステロール血症、高中性脂肪血症）や高血圧を引き起こし易く、これからやがて二次的な循環器傷害としての動脈硬化症、狭心症や心筋梗塞などの心臓病、脳梗塞や脳血栓などの脳血管疾患などの重大な障害をもたらすことになる。さらに、脂肪肝、胆石症、関節障害、大腸癌、胆のう癌、前立腺癌などの発症率も高くなる。したがって、速やかなダイエットがどうしても必要になる。
一方、皮下脂肪型肥満はすぐに病気を招くわけではないが内蔵脂肪型肥満に変わる場合が多いので、やはり解消する必要がある。
【００１２】
このような血液血管系疾患や糖尿病を誘発する可能性が高い肥満防止を目的として、食事療法が採用されたり、或いは多種の薬物や健康補助商品が提案されている。基本的には食べる量を減らす食事療法が確実であるが、食事療法は過度な制限食になることが多く、欧風の食事になれた現代社会において、長期に亙る食事制限を実行するには非常に困難を伴い、食欲に負けてしまうとリバウンドという結果になりやすく、減食とリバウンドを繰り返すとかえって内蔵に脂肪を蓄えることになってしまう。
【００１３】
このような食事療法に変わるものとして、肥満を防止するための薬剤の投与も行われているが、これらの薬剤は、医師の管理下において投与されるものであって一般的に使用できるものではない。
医師の管理を必要とせず、減食を行わないダイエットの方法として、食事を低カロリー食に切り替える方法があるが、嗜好に合わないものを摂取する方法ではやはり脱落者が出やすい。比較的容易な肥満防止の方法として栄養補助食品を用いる方法が優れている。このような栄養補助食品であれば、肥満や血糖値が高い人は便秘になりやすいがそれに対処した整腸作用をもつ成分や、ダイエットに伴う皮膚の乾きなどに対処できる成分を一緒に含めることもできる。
【００１４】
本発明は、糖質（炭水化物）の吸収を阻害する桑の葉を主成分として、整腸作用、抗酸化作用、皮膚の保湿作用を有する組成を含み、生活習慣病の予防、血糖値の降下、ダイエット、肥満回避を目的として、その初期段階から最終段階まで継続して用いることができる栄養補助食品を提供することを目的にしている。
【００１５】
以下本発明の栄養補助食品の各組成として用いられる桑の葉抽出物、ぶどう種子抽出物、セラミド含有小麦抽出物、アルギン酸ナトリウム含有海藻抽出物、ぶどう果汁末、デキストリンの各々に付いて説明する。
【００１６】
１）桑の葉抽出物
桑の葉には、ショ糖、果糖、ブドウ糖などの糖類、アスパラギン酸、グルタミン酸などのアミノ酸、各種ビタミンおよびカルシウム、鉄分、亜鉛などの金属類が含有されている。これらは、ダイエット中に栄養のバランスをとるうえに欠かすことができないビタミン、ミネラル類である。また、桑の葉は血糖値降下作用を有し、糖尿病を予防する効果があることが知られており、昔から漢方薬として用いられている。これは、植物では桑の葉だけに見られるＤＮＪ（デオキシノジマリマイシン）という成分が化学構造がブドウ糖に非常に似ているので、糖質の消化吸収にかかわるα−アミラーゼ、α−グルコシターゼなどの糖分解酵素がブドウ糖よりも先にＤＮＪと結合してしまい、糖の分解を抑制するためである。したがって、血糖値が下がり、ダイエットの効果も生まれる。ＤＮＪのために分解されなかった糖類は大腸に運ばれ、腸内細菌はこれを元に２酸化炭素や有機酸を生成する。これにより大腸は刺激を受け運動が高まり、これによっても便秘が改善され整腸の効果が生まれる。
桑の葉抽出物の一日の摂取量は９００ｍｇ以上２０００ｍｇ以下が好ましい。この値よりも小さいと糖の分解を抑制する効果が薄く、これ以上の値を摂取しても排出されてそれ以上の効果はない。
【００１７】
２）ぶどう種子抽出物
ぶどう種子抽出物にはポリフェノール中でも抗酸化力の最も強いプロアントシアニジンが９０％以上含まれている。
体内にはもともと酸化を抑える機能が備わっているが、何らかの作用で活性酸素などの発生と消去のバランスが崩れると、血液中のＬＤＬ（悪玉コレステロールを血中で運ぶ粒子）が酸化ＬＤＬに変化し、動脈硬化発症の引き金となる。さらに酸化ＬＤＬは血管自体を傷害し、血管の弾力性を奪い、血液の流れを悪化させる。ビタミン類やポリフェノールなどの抗酸化物質は、活性酸素による酸化ＬＤＬの発生やこれに伴う血管の傷害を防いで動脈硬化の進行を抑制する抗酸化力を有している。
【００１８】
ポリフェノールにはたくさんの種類がある。例えば、赤ワインにはフラボノールやカテキン、タンニン、アントシアニンなどの何種類ものポリフェノールが含まれていて、これにより、赤ワインには、ＬＤＬを酸化から守る働き以外に、血栓をできにくくする作用がある。ぶどう種子抽出物中のプロアントシアニジンは抗酸化作用の最も強いタイプのポリフェノールであり、血管治療薬（医薬品）としても使用され、人体に対する有効性と安全性が確認されている。さらに、プロアントシアニジンには動脈硬化、大腸癌、糖尿病といった生活習慣病の予防効果のほかに、白内障予防作用、胃潰瘍予防作用、筋肉疲労予防作用があることが確かめられている。
ぶどう種子抽出物の一日の摂取量は５０ｍｇ以上２００ｍｇ以下が好ましい。この値よりも小さいと抗酸化の効果が薄く、これ以上の値を摂取しても排出されてそれ以上の効果はない。
【００１９】
３）セラミド含有小麦抽出物
セラミドは、人の皮膚にも含まれる複合脂質であり、肌のみずみずしさと張りを保つ効果があるとされている。化粧品や肌の治療薬など外用で保湿効果を向上させるために用いられるが、このような例では、塗布した部分だけにしか効果がない。
しかし、食品として吸収すると、身体の中から全身の皮膚に保湿のバリアーを張る効果があり、肌のみずみずしさを保って乾燥肌やアトピー性皮膚炎の改善に効果があることが認められている。また、ダイエットを続けた場合に失われる細胞の水分を補い、皮膚細胞を活性化させる効果も知られている。したがって、本発明の栄養補助食品摂取のことに後期に必要とされる成分である。
セラミド含有小麦抽出物の一日の摂取量は１５ｍｇ以上３５ｍｇ以下が好ましい。この値よりも小さいと皮膚の保湿効果が薄くなり、これ以上の値を摂取してもそれ以上の効果はない。
【００２０】
４）アルギン酸ナトリウム含有海藻抽出物
アルギン酸ナトリウムはコンブなどに含まれる水溶性食物繊維であって、小腸で胆汁酸と結合して便として排泄され、胆汁酸の再吸収を抑制するため、胆汁酸が失われる。これを補うために血中コレステロールから胆汁酸を作る過程が活発になり、血中コレステロールを減らすことができる。また、便を適度に柔らかくしてボリュームを持たせる機能があり、これが腸を刺激して腸を整える作用がある。
アルギン酸ナトリウム含有海藻抽出物の一日の摂取量は５０ｍｇ以上２５０ｍｇ以下が好ましい。この値よりも小さいと血中コレステロールを減らす効果が薄い。
【００２１】
５）ぶどう果汁末
本発明の栄養補助食品には、摂取を容易にするため、味付けの目的でぶどう果汁末が加えられている。ぶどう果汁末の一日の摂取量は５０ｍｇ以上５００ｍｇ以下が好ましい。
【００２２】
６）デキストリン
デキストリンは、馬鈴薯澱粉から抽出した食物繊維で現代人に不足がちな食物繊維を補い、整腸作用を有しており、また、糖の吸収を穏やかにするため、血糖値の改善にも役立つ。さらに、本発明の栄養補助食品の口当たりをよくする効果もある。デキストリンの一日の摂取量は特に限定しないが本発明の栄養補助食品の他の成分の合計重量と同等かその倍程度の量が好ましいものと考えられる。
【００２３】
本発明の栄養補助食品は、以上のような各成分を含んでおり、それぞれの成分の血糖値降下機能、整腸する機能、血中コステロールを減らす機能、生活習慣病の予防効果、肌の保湿機能などは相互に作用しあって複合され、単体で用いた場合よりも大きな効果をあげることができる。
さらに、これらの成分には、桑の葉抽出物の糖の分解を抑制する効果のように摂取を始めた初期段階から直接効果をあげる機能と、永続的に摂取することによって体質が改善されたあとに特に必要となるセラミドなどの成分が組み合わされているので、栄養補助食品摂取の初期段階から最終段階まで一貫して用いることができる。
【００２４】
また、各成分が自然食品から抽出される成分であるので、長期に摂取しても安全であり、本発明の栄養補助食品を用いて健康を害することなく無理なくダイエットを行うことができる。
本発明の栄養補助食品の摂取は、以上に述べた各成分の一日の摂取量を組み合わせて４．５ｇないし１０ｇとし、これを３回ないし５回程度に分けて朝、昼、夕の各食事の直前か食事中および食間時にとるようにするのが望ましい。これによって、楽に摂取することができるし、本発明の栄養補助食品の各組成が無駄なく吸収される。
【００２５】
【発明の効果】
以上述べたように、本発明の栄養補助食品は、生活習慣病の予防、血糖値の降下、ダイエット、肥満回避の効果を有し、口当たりがよく無理なく継続した摂取が可能で、摂取の初期段階から最終段階まで一貫して用いることができ、これを用いることで、健康を害することなく無理なくダイエットを行うことができる。[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a dietary supplement, and more particularly, to a dietary supplement using mulberry leaves that is effective in lowering blood sugar levels and dieting.
[0002]
[Prior art]
As a dietary supplement mainly using mulberry leaves, those using extracts of mulberry leaves and agarisk (see Patent Document 1) and those obtained by subjecting mulberry leaf extracts to propolis processing (see Patent Document 2). Mulberry leaf powder and oyster powder (see Patent Literature 3), mulberry leaf and chitosan (see Patent Literature 4), and mulberry leaf and silkworm feces containing sake. And dried and powdered (see Patent Document 5), and those using mulberry leaves and plum meat as materials (see Patent Document 6). As one of them, many reports using mulberry leaves have been reported.
[0003]
However, previous reports lack the perspective that they can be used consistently from the beginning to the end of treatment, and how much per day should be used for each composition to work effectively. It is not so clear what is good.
[0004]
[Patent Document 1]
JP 2001-213796 A (Page 2-5, FIG. 1)
[Patent Document 2]
JP 2001-103943 A (page 2)
[Patent Document 3]
JP 2001-48794 A (pages 2 to 7)
[Patent Document 4]
JP-A-2000-281584 (page 3-4)
[Patent Document 5]
JP-A-2000-157206 (page 2-3, FIG. 1)
[Patent Document 6]
JP-A-10-127253 (page 3-8, FIG. 1)
[0005]
[Problems to be solved by the invention]
As mentioned above, dietary supplements containing mulberry leaves as a main component, which have been reported so far, lack the viewpoint that they can be used consistently from the initial stage to the final stage of dietary supplement intake, In addition, it has not been clear how much each composition should take in order to work effectively.
The present invention is a dietary supplement containing a plurality of components mainly composed of mulberry leaf extract, which can be used safely for the purpose of preventing lifestyle-related diseases, lowering blood sugar levels, dieting, avoiding obesity, In addition, it can be used consistently from the initial stage to the final stage of ingestion of the dietary supplement, multiple ingredients work more effectively than when used alone, and they are more palatable and easier to consume, and each An object of the present invention is to propose a dietary supplement in which the daily intake and the content ratio of each component necessary for producing a sufficient effect of the components are clear.
[0006]
[Means for Solving the Problems]
In order to solve the above problems, the dietary supplement of the present invention comprises a mulberry leaf extract, a grape seed extract, a ceramide-containing wheat extract, and a sodium alginate-containing seaweed extract. It is characterized by.
As a result, it can be used consistently from the initial stage to the final stage of dietary supplement intake for the purpose of preventing lifestyle-related diseases, lowering blood sugar levels, dieting, and avoiding obesity. A dietary supplement that can be performed can be realized.
[0007]
In addition, the dietary supplement of the present invention is characterized in that it further contains grape juice powder and dextrin.
This makes it possible to achieve a dietary supplement that is palatable and can be taken without difficulty.
[0008]
In addition, the dietary supplement of the present invention contains 900 mg to 2000 mg of mulberry leaf extract, 50 mg to 200 mg of grape seed extract, 15 mg to 35 mg of ceramide-containing wheat extract, and sodium alginate in 4.5 g to 10 g of daily intake. It is characterized by containing 50 mg to 250 mg of seaweed extract.
As a result, each component works effectively, and each component works more effectively than when used alone.It is a dietary supplement that is effective in preventing lifestyle-related diseases, lowering blood sugar levels, dieting, avoiding obesity, etc. can do.
[0009]
Further, the dietary supplement of the present invention is characterized by further comprising 50 mg to 500 mg of grape juice powder in a daily intake of 4.5 g to 10 g and an appropriate amount of dextrin.
As a result, it is possible to realize a dietary supplement that is palatable and can be ingested without difficulty and that has a good mixing ratio of the intake amounts of the respective components.
[0010]
Furthermore, the dietary supplement of the present invention may be divided into three to five doses of the daily intake of 4.5 g to 10 g and taken immediately before each meal in the morning, afternoon, and evening, or during or during a meal. It is characterized by the following.
As a result, each composition of the dietary supplement of the present invention is reasonably ingested and absorbed, and each time the effect is increased, such as suppressing the decomposition of sugar and lowering the blood sugar level.
[0011]
BEST MODE FOR CARRYING OUT THE INVENTION
In recent years, obesity has also increased in Japanese people due to Westernization of dietary habits (increased intake of saturated fatty acids), overeating (increased calorie intake), and lack of exercise (lack of calorie consumption). Conceivable.
Obesity is classified into visceral fat obesity and subcutaneous fat obesity depending on where fat is accumulated. Visceral fat type obesity is the accumulation of fat in the visceral organs, and such obese people are said to be morbidly obese because they tend to develop lifestyle-related diseases that were once considered as adult diseases. Blood vascular diseases and diabetes are particularly common among lifestyle-related diseases. It is easy to cause hyperlipidemia (hypercholesterolemia, hypertriglyceridemia) and hypertension in blood vascular diseases, and in the future, secondary circulatory injuries such as arteriosclerosis, angina pectoris and myocardial infarction It can cause serious disorders such as heart disease, cerebral infarction and cerebrovascular disease such as cerebral thrombosis. Furthermore, the incidence of fatty liver, cholelithiasis, joint disorders, colorectal cancer, gallbladder cancer, prostate cancer and the like also increases. Therefore, a quick diet is absolutely necessary.
On the other hand, subcutaneous fat-type obesity does not immediately lead to illness but often changes to visceral fat-type obesity, so that it is necessary to eliminate it.
[0012]
For the purpose of preventing obesity, which is highly likely to induce such blood vascular diseases and diabetes, diet therapy has been adopted, or various kinds of drugs and health supplement products have been proposed. Basically, diets that reduce the amount of food eaten are certain, but diets often lead to excessive dietary restrictions, and it is extremely difficult to implement long-term dietary restrictions in a modern society that has become a European-style diet. If you lose your appetite, you can easily end up rebounding, and if you repeatedly reduce and rebound, you will end up storing fat inside.
[0013]
As an alternative to such a diet, administration of drugs for preventing obesity has also been performed, but these drugs are administered under the control of a physician and are not generally available. Absent.
As a dieting method that does not require the management of a doctor and does not reduce meals, there is a method of switching the diet to a low-calorie diet. However, a method of ingesting foods that do not suit the taste tends to cause dropouts. As a relatively easy method for preventing obesity, a method using dietary supplements is excellent. If such a dietary supplement is used, people who have obesity or high blood sugar levels tend to have constipation but have an intestinal action that can cope with constipation, and an ingredient that can cope with dry skin caused by dieting. You can also.
[0014]
The present invention comprises mulberry leaves that inhibit the absorption of carbohydrates (carbohydrates) as a main component, and has a composition having an intestinal action, an antioxidant action, and a skin moisturizing action, preventing lifestyle-related diseases, lowering blood sugar levels. It is an object of the present invention to provide a dietary supplement that can be used continuously from the initial stage to the final stage for the purpose of dieting and avoiding obesity.
[0015]
The mulberry leaf extract, grape seed extract, ceramide-containing wheat extract, sodium alginate-containing seaweed extract, grape juice powder, and dextrin used as the components of the dietary supplement of the present invention will be described below.
[0016]
1) Mulberry leaf extract Mulberry leaves contain sugars such as sucrose, fructose and glucose, amino acids such as aspartic acid and glutamic acid, various vitamins and metals such as calcium, iron and zinc. These are the vitamins and minerals that are essential to balance nutrition during a diet. Also, mulberry leaves are known to have a blood sugar lowering effect and have an effect of preventing diabetes, and have been used as a Chinese medicine since ancient times. This is because the chemical structure of DNJ (deoxynojimarimycin), which is found only in mulberry leaves, is very similar to glucose in plants, so that α-amylase, α-glucosidase, etc. involved in the digestion and absorption of carbohydrates This is because the glycolytic enzyme binds to DNJ before glucose and suppresses the decomposition of sugar. Therefore, the blood sugar level decreases, and a diet effect is also produced. Sugars that are not decomposed due to DNJ are transported to the large intestine, from which intestinal bacteria produce carbon dioxide and organic acids. This stimulates the large intestine to increase movement, which also improves constipation and produces an intestinal effect.
The daily intake of mulberry leaf extract is preferably 900 mg or more and 2000 mg or less. If the value is smaller than this value, the effect of suppressing the decomposition of sugar is weak, and even if the value is taken beyond this value, it is excreted and has no further effect.
[0017]
2) Grape seed extract Grape seed extract contains 90% or more of proanthocyanidins having the strongest antioxidant power among polyphenols.
The body originally has a function of suppressing oxidation, but if the balance between the generation and elimination of active oxygen is lost by some action, LDL (particles that carry bad cholesterol in the blood) in the blood changes to oxidized LDL. Triggers the development of arteriosclerosis. In addition, oxidized LDL damages blood vessels themselves, deprives blood vessels of elasticity and impairs blood flow. Antioxidants, such as vitamins and polyphenols, have antioxidant power to prevent the generation of oxidized LDL due to active oxygen and the resulting damage to blood vessels and to suppress the progress of arteriosclerosis.
[0018]
There are many types of polyphenols. For example, red wine contains several types of polyphenols, such as flavonols, catechins, tannins, and anthocyanins. Thus, red wine has an effect of preventing blood clots from being formed, in addition to an effect of protecting LDL from oxidation. Proanthocyanidin in grape seed extract is a polyphenol having the strongest antioxidant activity, and is also used as a vascular treatment drug (medicine), and its efficacy and safety on the human body have been confirmed. Furthermore, it has been confirmed that proanthocyanidin has an effect of preventing cataract, an effect of preventing gastric ulcer, and an effect of preventing muscle fatigue in addition to an effect of preventing lifestyle-related diseases such as arteriosclerosis, colorectal cancer, and diabetes.
The daily intake of grape seed extract is preferably 50 mg or more and 200 mg or less. If the value is smaller than this value, the antioxidant effect is weak, and if a value higher than this value is ingested, it is excreted and has no further effect.
[0019]
3) Ceramide-containing wheat extract Ceramide is a complex lipid also contained in human skin, and is said to have an effect of keeping the skin fresh and firm. It is used to improve the moisturizing effect in external applications such as cosmetics and skin remedies, but in such an example, it is effective only on the applied portion.
However, it is recognized that when absorbed as food, it has the effect of providing a moisturizing barrier from the inside of the body to the skin of the whole body, keeping the freshness of the skin and improving dry skin and atopic dermatitis . It is also known that the effect of supplementing the water lost in cells when dieting is continued and activating skin cells is known. Therefore, it is a component that is required at a later stage in the dietary supplement intake of the present invention.
The daily intake of the ceramide-containing wheat extract is preferably from 15 mg to 35 mg. If the value is smaller than this value, the moisturizing effect of the skin is reduced, and if a value higher than this value is taken, there is no further effect.
[0020]
4) Sodium alginate extract containing sodium alginate Sodium alginate is a water-soluble dietary fiber contained in kelp and the like, which binds to bile acids in the small intestine and is excreted as stool, thereby suppressing bile acid reabsorption. Lost. To make up for this, the process of making bile acids from blood cholesterol becomes active and blood cholesterol can be reduced. In addition, the stool has a function of appropriately softening the stool to have a volume, and this function has a function of stimulating the intestine and preparing the intestine.
The daily intake of the seaweed extract containing sodium alginate is preferably 50 mg or more and 250 mg or less. If it is lower than this value, the effect of reducing blood cholesterol is weak.
[0021]
5) Grape Juice Powder Grape juice powder is added to the dietary supplement of the present invention for the purpose of seasoning to facilitate ingestion. The daily intake of grape juice powder is preferably 50 mg or more and 500 mg or less.
[0022]
6) Dextrin Dextrin is a dietary fiber extracted from potato starch that supplements dietary fiber, which is deficient in modern humans, and has an intestinal action. Also helps. Further, there is also an effect of improving the palatability of the dietary supplement of the present invention. Although the daily intake of dextrin is not particularly limited, it is considered that an amount equivalent to or twice the total weight of the other components of the dietary supplement of the present invention is preferable.
[0023]
The dietary supplement of the present invention contains each of the above components, and each component has a blood sugar lowering function, a bowel regulating function, a function of reducing blood costosterol, a preventive effect on lifestyle-related diseases, The moisturizing function and the like interact with each other and are combined, and can provide a greater effect than when used alone.
In addition, these components have a direct effect from the initial stage of ingestion, such as the effect of mulberry leaf extract on inhibiting sugar degradation, and improved constitution by ingesting permanently Since components such as ceramide, which are particularly required later, are combined, they can be used consistently from the initial stage to the final stage of dietary supplement intake.
[0024]
Moreover, since each component is a component extracted from natural foods, it is safe even if it is taken for a long period of time, and it is possible to use a dietary supplement of the present invention to make a diet without harm to health.
Ingestion of the dietary supplement of the present invention is performed by combining the daily intake of each component described above to 4.5 g to 10 g, and dividing this into about 3 to 5 times each in the morning, afternoon, and evening. It is desirable to take it just before meals, during meals, and between meals. Thereby, it can be easily taken, and each composition of the dietary supplement of the present invention is absorbed without waste.
[0025]
【The invention's effect】
As described above, the dietary supplement of the present invention has the effects of preventing lifestyle-related diseases, lowering blood sugar levels, dieting, and avoiding obesity. It can be used consistently from the stage to the final stage, and by using this, it is possible to carry out a diet without harm to health.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003126366A JP2004329047A (en) | 2003-05-01 | 2003-05-01 | Dietary supplement |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003126366A JP2004329047A (en) | 2003-05-01 | 2003-05-01 | Dietary supplement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2004329047A true JP2004329047A (en) | 2004-11-25 |
Family
ID=33503327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003126366A Pending JP2004329047A (en) | 2003-05-01 | 2003-05-01 | Dietary supplement |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2004329047A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006035700A1 (en) * | 2004-09-27 | 2006-04-06 | Suntory Limited | Composition containing proanthocyanidin and sphingolipid |
| WO2006068041A1 (en) * | 2004-12-20 | 2006-06-29 | Okayasu Shoten Co., Ltd. | Composition having effect of promoting the decomposition of body fat and food or food additive containing the same |
| JP2011057707A (en) * | 2010-12-21 | 2011-03-24 | Nagasakiken Koritsu Daigaku Hojin | Composition for suppressing blood glucose level increase, food for suppressing blood glucose level increase, and composition for inhibiting disaccharide hydrolase activity |
| JP2016052290A (en) * | 2014-09-04 | 2016-04-14 | 株式会社日清製粉グループ本社 | Dietary fiber-fitted non-dry or half-dry small pasta |
| JP2016188180A (en) * | 2015-03-30 | 2016-11-04 | 株式会社東洋新薬 | Composition containing specific component |
| JP2018027021A (en) * | 2016-08-15 | 2018-02-22 | アサヒビール株式会社 | Composition for trans-2-hexenal generation, trans-2-hexenal generation flavor composition and product containing the same |
| JP2021061789A (en) * | 2019-10-15 | 2021-04-22 | サムライ金沢株式会社 | Food composition and feed composition |
| WO2021132053A1 (en) * | 2019-12-27 | 2021-07-01 | サントリーホールディングス株式会社 | Tea beverage containing sodium |
-
2003
- 2003-05-01 JP JP2003126366A patent/JP2004329047A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006035700A1 (en) * | 2004-09-27 | 2006-04-06 | Suntory Limited | Composition containing proanthocyanidin and sphingolipid |
| WO2006068041A1 (en) * | 2004-12-20 | 2006-06-29 | Okayasu Shoten Co., Ltd. | Composition having effect of promoting the decomposition of body fat and food or food additive containing the same |
| JP2011057707A (en) * | 2010-12-21 | 2011-03-24 | Nagasakiken Koritsu Daigaku Hojin | Composition for suppressing blood glucose level increase, food for suppressing blood glucose level increase, and composition for inhibiting disaccharide hydrolase activity |
| JP2016052290A (en) * | 2014-09-04 | 2016-04-14 | 株式会社日清製粉グループ本社 | Dietary fiber-fitted non-dry or half-dry small pasta |
| JP2016188180A (en) * | 2015-03-30 | 2016-11-04 | 株式会社東洋新薬 | Composition containing specific component |
| JP2018027021A (en) * | 2016-08-15 | 2018-02-22 | アサヒビール株式会社 | Composition for trans-2-hexenal generation, trans-2-hexenal generation flavor composition and product containing the same |
| JP2021061789A (en) * | 2019-10-15 | 2021-04-22 | サムライ金沢株式会社 | Food composition and feed composition |
| WO2021132053A1 (en) * | 2019-12-27 | 2021-07-01 | サントリーホールディングス株式会社 | Tea beverage containing sodium |
| JP2021103999A (en) * | 2019-12-27 | 2021-07-26 | サントリーホールディングス株式会社 | Tea beverage containing sodium |
| JP7337687B2 (en) | 2019-12-27 | 2023-09-04 | サントリーホールディングス株式会社 | tea drinks containing sodium |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6413545B1 (en) | Diet composition and method of weight management | |
| US6638542B2 (en) | Reducing appetite in mammals by administering procyanidin and hydroxycitric acid | |
| CN104872504A (en) | Meal-replacing powder capable of replacing daily diet and having balanced nutrition and preparation method of meal-replacing powder | |
| AU2001241762A1 (en) | Nutritional intervention composition for enhancing and extending satiety | |
| CN101507494A (en) | Special diet food for patient with hyperlipidemia and hypertension | |
| US20060045924A1 (en) | Dried fruit composition with laxative effects and method for administration thereof | |
| CA2316671A1 (en) | Nutritional products and method for treating and preventing cancer and other degenerative diseases | |
| KR20040095949A (en) | Composition comprising herb with usage to prevent obeseness | |
| JP2004329047A (en) | Dietary supplement | |
| KR100336644B1 (en) | The composites of raw-type tea with anti-obese function | |
| KR20200043555A (en) | Supplement food composition for diet | |
| KR20060024766A (en) | Food for improving clinical conditions capable of lowering the concentration of low-molecular weight nitrogen-containing compounds in blood | |
| US6506420B2 (en) | Combinations of psyllium and chitosan for synergistic adsorption of triglyceride | |
| KR19980085889A (en) | Obesity-controlled health food containing extracts of copper, red beans, multileaf and upper limb | |
| WO2014016265A1 (en) | Hawthorn and phytosterols and their effect on metabolic disorders | |
| CN1307826A (en) | Functional food and its use | |
| JP2006020606A (en) | Composition for health food for obesity prevention and amelioration | |
| KR20140065924A (en) | Onion peel powder material by creating supplements | |
| JP2009034017A (en) | Diet food | |
| KR100336646B1 (en) | The composites of raw-type tea containing arabinoxylane | |
| KR20040031398A (en) | Diet-food Composition characterized as blocking to absorb carbohydrate and lipid | |
| CN109007662A (en) | A kind of weight-reducing preparation having both beautifying face and moistering lotion | |
| KR20160084091A (en) | A manufacturing method of functional foods using glutinous as main material | |
| CN101011565A (en) | Health food with oxidation resistance and compact bone substance density intensification functions | |
| KR20020079065A (en) | How to make porridge using seaweed, seaweed, seaweed, and seaweed |