KR19980085889A - Obesity-controlled health food containing extracts of copper, red beans, multileaf and upper limb - Google Patents

Abstract

According to the present invention, powders, granules, which can inhibit and prevent obesity and various adult diseases, including copper, red beans, multi-leaf and upper limb as main ingredients, and various herbal medicines, food materials, vitamins and minerals as auxiliary ingredients. Tablets, capsules, beverages and porridge products are provided. The health food of the present invention can efficiently reduce body fat even without reducing the amount of meals and does not interfere with social life.

Description

Obesity-controlled health food containing extracts of copper, red beans, multileaf and upper limb

The present invention relates to a dietary health food for the control of obesity.

As the national economy develops, obesity is becoming a threat to national health as people consume more processed foods with high energy content and have less exercise. Obesity not only gives a bad image and uncomfortable appearance to the viewer, but also obesity, and the obesity rate of diabetes, arteriosclerosis, hypertension, heart disease, liver disease, gallstones, gout, kidney disease, etc. It is reported that the risk of surgery is high and generally short-lived. Therefore, obesity is a life issue for those who are over the middle age, and is considered seriously for young women, especially for cosmetic reasons.

Recently, with the appropriate exercise as a prevention and treatment of adult diseases such as obesity, there is a growing interest in the use of various food materials that have been proven safety and efficacy for many years. Currently, products containing dietary fiber, herbal medicines and various food ingredients have been developed as a health food for obese people.However, if you reduce the amount of meals and consume these products, normal life is difficult due to side effects due to lack of various nutrients. It is known to quickly become obese again.

The inventors of the present invention as a health food that can effectively prevent and suppress obesity and related diseases, even if ingested and reducing the amount of meals can effectively reduce body fat without disrupting normal social life, the health food for controlling obesity In order to develop obesity control health foods that do not return to the state of obesity within a certain period of time even if you stop taking, repeated experiments combining various herbal medicines, functional food materials, vitamins, and minerals in various ratios, The effect was demonstrated experimentally to complete the present invention.

That is, according to the present invention, there is provided a health food for controlling obesity and a method of manufacturing the same, by minimizing side effects by adding various auxiliary ingredients to extracts of copper, red beans, multileaf and upper limb.

Among the herbal components of the present invention, the gingiva is effective in treating several species and hepatic diseases, promotes diuretic action and strengthens the exercise function of the large intestine [Isijin, Herbal Tree, Torture History (1987)]. In general, it is known that dietary obesity requires strengthening the motor function of the small intestine, which suppresses diuretic function and constipation (Science Encyclopedia, Longevity Health, Ilwol Seokji (1990)).

Red beans act as a suppressant and diuretic effect of tree species and sorghum (Heo Jun, Dong Bogam, Namsan Dang (1988)), and tea leaves have sulfate action and prevent cardiovascular disease [Biol, Pharm. Bull. 18, 1006 (1995). In addition, the upper limb has a diuretic effect and hypertension suppression [新 文 豊 出版 公司 新編 中藥 大 辭典, 臺北 (中華民國 71 年)].

The present invention is explained in more detail below.

Copper, one of the main raw materials of the present invention is freeze, dried or hot-air dried at 40-80 ° C. together with the skin and seeds after removing foreign matters, or only the seeds are removed and used to cut or grind the living body. When cutting and using the copper fruit, it is preferable to cut so that the size of a piece may be 3 mm or less. The red beans are boiled, dried together with the juice and crushed. The multileaf is dried and ground to use, or hot water extracted and concentrated under reduced pressure, followed by powdering by adding 40% dextrin. The upper limbs are roasted so that the surface of the upper limb is pale yellow, or hot water extracted in the same way as the multileaf after roasting, concentrated under reduced pressure, and powdered.

The amount of the main ingredient to be blended in the obesity control health food according to the present invention, based on weight, 40 to 90% copper and 10 to 60% copper powder, 2 to 40% red beans, 5 to 25% or multi-leaf extract Preference is given to 1-6% of powder, 5-30% of roasted upper extremity or 1-15% of upper extremity extract powder.

Auxiliary components of the health food may include an appropriate amount of kelp, black beans, perilla, chitosan, garcinia cambogia extract, Angelica, propolis, pine needles, yeast, Seokchangpo, jujube, astronomical dong, baekbokyeong, yulmu, vitamins, minerals, etc., preferably Preferably it is included in an amount of 10% to 80% of the total weight of the health food. Auxiliary ingredients are extracted or pulverized by conventional methods or used in the same methods and conditions as those used in conventional health foods or herbal medicines. Kelp is immersed in water to remove salt and then dried and crushed.

Since the main ingredient and the auxiliary ingredient contained in the health food composition of the present invention have all been used as herbal medicines, food ingredients and food or pharmaceutical additives since ancient times, safety of the human body is excellent when taken or ingested.

The composition according to the present invention may be powdered or extracted according to a conventional method and formulated in the form of capsules, tablets, granules, powders, beverages, porridges and the like.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited to these Examples.

EXAMPLE

Example 1

After removing foreign matters, the fruit was cut into small pieces and dried in hot air at 80 ° C. together with shells and seeds to powder. The upper limb was roasted to make the surface of the upper limb pale yellow, hot water extracted, concentrated under reduced pressure, and powdered by adding 40% dextrin. The red beans were boiled, dried with the juice and powdered. The multileaf was dried and ground.

Example 2

Copper powder 25%, Red beans 10%, Multileaf extract powder 2%, Upper lichen extract powder 5%, Kelp 2%, Roasted black beans 23%, Roasted perilla 11%, Roasted roasted radish 13%, Baekboknyeong 5%, Vitamin and mineral mixture 4 The powder was prepared by mixing the%. [Composition of vitamin-mineral mixture (%): vitamin A 0.05, vitamin C 12.9, vitamin D 0.0003, vitamin B ₁ 0.09, vitamin B ₂ 0.1, vitamin B ₆ 0.1, vitamin B ₁₂ 0.0003, folic acid 0.01, niacin 1.2, seaweed Calcium 36.5, magnesium chloride 47.6, iron lactate 0.9, zinc oxide 0.5]

Example 3

Copper fruit powder 25%, the extract powder 5%, multi-leaf extract powder 3%, red beans 10%, Seokchangpo extract powder 5%, cheonmundong 5%, Garcinia cambogia extract (68% citric acid hydroxide) 5%, Baekbokyeong 5%, Yulmu 10 Granules were prepared according to a conventional method by mixing%, pine needles 5%, propolis 5%, Angelica extract 3%, vitamin-mineral mixture 12% and yeast 2%. [The composition of the vitamin-mineral mixture is the same as in Example 2]

Example 4

The granules prepared in Example 2 were compressed into tablets according to a conventional method to obtain tablets (200 mg each).

Example 5

The powder obtained in Example 1 was filled into hard gelatin capsules (400 mg each).

Example 6

20 times of water was added to a raw material mixture of 55% of living animals, 55% of upper limbs, 10% of multilobes, 5% of red beans, 10% of jujubes, and 10% of vitamin-mineral mixtures, and extracted at 70 ° C. for 1 hour. [The composition of the vitamin-mineral mixture is the same as in Example 2] After centrifugation, 20 times of water was added to the solid, extracted under the same conditions, and centrifuged. Discard the solid residue, combine the two extracts and concentrate under reduced pressure (30-50 mmHg) at 50 ° C to double the weight of the composition before extraction, filter with a 3 micron filter and sterilize at 75-80 ° C for 30 minutes, then filter 200 mesh Through the device, the filtrate is filled and sealed in a pre-sterilized container to be a beverage.

Example 7

83% of copper and biomedium cut to 3 mm or less, multi-leaf extract powder 1%, upper extremity extract powder 2%, boiled red beans 4%, red radish 4%, kelp powder 2%, rice 4% and vitamin-mineral mixture 10% The porridge was prepared according to a conventional method by the composition. [The composition of the vitamin-mineral mixture is the same as in Example 2]

Experimental Example 1

Obesity Inhibitory Effect Experiment (Animal Experiment)

(1) animal experiment

The animals used in this experiment were male Sprague-Dawley rats. Four-week-old rats were purchased, fed a commercial pellet feed for one week, and then divided into 10 groups. The normal control group continued to feed only pellets and all other groups fed the pellets with a cafeteria diet, which is known to cause obesity closest to the most common types of obesity in humans, and freed up all feed and water. . After feeding the cafeteria diet for 2 weeks, distilled water was added to each of the main ingredients of the health food obtained in Example 1 of the present invention, and a mixture of the four ingredients, so that the mixture was 0.4 ml, and orally administered twice a day. The control group was orally administered the same volume of saline. Samples were administered orally with a 6-week cafeteria diet. The doses were converted from the daily use of humans and the weight ratio of humans and rats. The cafeteria diet was fed cookies, biscuits, chocolate, peanuts, cheese, potato chips, almonds, sausages and ham.

After oral administration of the sample for 6 weeks, blood was collected from the heart, and liver, kidney fat tissue (perirenal fat pad) and epididymal fat tissue (epididymal fat pad) were cut and weighed.

(2) chemical analysis

To analyze hepatic triglycerides, hepatic lipids were extracted and neutral lipids were quantified by enzyme method. Serum total cholesterol, HDL-cholesterol and glucose content were analyzed using a dry chemistry system (manufactured by Daiichi, Japan).

(3) Test result

The results of the obesity inhibitory function of the health food main ingredient according to Example 1 are shown in Table 1 below. Compared with the obese control group, copper and powder among the four main components reduced the weight gain by 6% and the caloric intake. All four components inhibited abdominal fat accumulation, and multileaf powder and upper limb extract inhibited liver triglyceride accumulation. Red bean powder and upper extremity extracts decreased blood sugar levels, and copper powder, multileaf powder and upper extremity extracts reduced the risk of arteriosclerosis compared to the obese control group. When the four main ingredients were fed together, the weight gain decreased by 10% compared to the obese control group, and the weight gain was more suppressed than the copper and powder only diet, and all other measures were lower than the one ingredient alone. Content, arteriosclerosis risk index and blood glucose level were the same as the normal control. These results demonstrate that copper powder, red bean powder, multi-leaf powder and upper limb extract can all suppress weight gain and suppress obesity, as well as reduce calorie intake, abdominal fat accumulation and atherosclerosis risk index. Give it. In addition, when the above four components are combined in a certain ratio, the effect of inhibiting the obesity and related diseases of the composition of the composition is further increased to more effectively inhibit obesity and related diseases such as fatty liver, arteriosclerosis, and diabetes mellitus. Is showing.

TABLE 1

Obesity inhibitory effect ¹

1. Mean ± SE (standard error). 10 per group. Values with different superscripts in the same column are significantly different. (P0.05)

2. 5 days before slaughter

3. (Total Cholesterol-HDL-Cholesterol) / HDL-Cholesterol

In addition, the results of investigation of the anti-obesity function of the composition prepared in Examples 2, 3, 4, 6, and 7 of the present invention are shown in Table 2 below. All groups given the composition of the present invention significantly inhibited weight gain, calorie intake, abdominal fat accumulation and hepatic triglyceride accumulation as compared to the obesity control group, and also reduced atherosclerosis risk index and blood glucose concentration. These results demonstrate that the compositions prepared in each example can effectively inhibit obesity and related diseases such as fatty liver, arteriosclerosis, and diabetes. In particular, ingesting the composition according to Examples 2 and 3, despite the fact that the diet was fed a cafeteria diet sample, such as the obesity control, factors such as weight gain and body fat were inhibited to the extent comparable to the normal control did not cause obesity Able to know.

TABLE 2

Obesity Inhibitory Effect Experiment Results ¹

1. Mean ± SE (standard error). 10 per group. Values with different superscripts in the same column are significantly different (P0.05)

2. 5 days before slaughter

3. (Total Cholesterol-HDL-Cholesterol) / HDL-Cholesterol

Experimental Example 2

Obesity Inhibitory Effect Experiment (Clinical Experiment)

Standard weight (kg) = [height (cm)-100] × 0.9

Obesity degree (%) = (actual weight-standard weight) / (standard weight) × 100

Five adult men and women with obesity of 30% or more calculated by the above two formulas were given 8 g of granules according to Example 3 before breakfast and lunch, and 40 g of powder according to Example 2 in the evening. . The 28-day intake resulted in an average weight loss of 3.64 kg compared to before consumption. In addition, the average body weight gain for 28 days after ingestion was 0.72 kg. These results prove that the obesity control health food composition of the present invention can effectively suppress obesity in humans, and when the intake is stopped, yoyo phenomena that rapidly gain weight do not appear.

Obesity control as well as diseases associated with obesity, as shown in the results of the above experiments, as shown in the results of the experimental examples, the main ingredient of the fruit, red bean, multi-leaf and upper limb and containing herbal medicines, food ingredients, vitamins and minerals as auxiliary ingredients Phosphorus effectively suppresses fatty liver, arteriosclerosis, and diabetes.

Claims (5)

40-90% of the vesicles or 10-60% of the pods, red beans 2-40%, 5-20% of the multileaf, or 1-6% of the multileaf extract powder, 5-30% of the roasted upper extremity or 1-15% of the upper extremity extract powder. Obesity control health food composition containing the main ingredient. According to claim 1, at least one auxiliary selected from the group consisting of kelp, black beans, perilla, chitosan, garcinia cambogia extract, propolis, donkey, pine needles, yeast, Seokchangpo, jujube, astronomical dong, baekbokyeong, yulmu, vitamins, minerals The composition further comprises the component in an amount of 10-80%. The composition according to claim 1 or 2, wherein the copper powder is lyophilized with shells and seeds or powdered by hot air drying at 40-80 ° C. The composition of claim 1 or 2, wherein the extract powder is roasted so that the surface of the upper limb is pale yellow, hot water extracted, concentrated under reduced pressure, and powdered with 40% dextrin. The composition of claim 1 or 2, which is in the form of a powder, granule, tablet, capsule, beverage or porridge.