CN102764209A - Cosmetic composition and preparation method thereof - Google Patents

Cosmetic composition and preparation method thereof Download PDF

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Publication number
CN102764209A
CN102764209A CN2012102132222A CN201210213222A CN102764209A CN 102764209 A CN102764209 A CN 102764209A CN 2012102132222 A CN2012102132222 A CN 2012102132222A CN 201210213222 A CN201210213222 A CN 201210213222A CN 102764209 A CN102764209 A CN 102764209A
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skin
weight
cosmetic composition
coenzyme
cosmetic
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王乃龙
谢志辉
罗嵘
李传茂
章志强
林新文
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Mentholatum China Pharmaceuticals Co Ltd
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Mentholatum China Pharmaceuticals Co Ltd
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Abstract

The invention relates to a cosmetic composition (i.e., D-3 skin activating ingredient (Derm-3Complex)). The cosmetic composition comprises 0.001-10.0 wt % of a wheat seed extract, 0.001-10.0 wt% of coenzyme Q10, 0.001-10.0 wt% of sodium hyaluronate; and an effective amount of cosmetically acceptable carrier. The invention also relates to a preparation method of the cosmetic composition. The cosmetic composition provided by the invention is a unique skin activating substance latest launched by Mentholatum company, contains three highly effective active ingredients, and has the following functions on the skin: defense: reducing damage on the skin by external environment and skin fine wrinkles, and fading aging marks of the skin; repair: effectively resisting against a variety of skin problems, such as drying, dullness and tiredness, enhancing repair function of the skin and restoring the skin to a young state; and improvement: promoting elasticity and tension of the skin, and realizing more flexible and elastic skin.

Description

A kind of cosmetic composition and preparation method thereof
Technical field
The present invention relates to cosmetic field, specifically, the present invention relates to a kind of cosmetic composition and preparation method thereof.
Background technology
The skin-active composition is one of emphasis problem of current cosmetics research; People hope to find a kind of efficient skin-active composition always; The influence that helps skin opposing surroundings and skin aging to bring, and replenish skin nutrition rapidly, let skin quickly recover to the healthy colour of skin.A lot of science and technology show that the main cause of skin ageing is exactly oxidation and saccharifying.Saccharification react and age, all it doesn't matter for skin matter, is the problem that all can face at any age, just as antioxidation; We begin oxidized once being born, just when we were young, skin can carry out normal metabolic; Can repair oxidation, saccharifying equivalent damage, but with age, the human body function fails gradually; Skin Cell is difficult to easily fall this part unnecessary free sugar metabolism, and saccharifying has just become the major reason of skin ageing.That skin after the saccharifying can become is coarse, do not have elasticity, dark yellow, speckle, lose transparent feel.
The skin-active composition of cosmetics aspect defying age mainly considered anti-oxidation efficacy at present, seldom studies for anti-saccharifying effect, and be often out in the cold.Emphasis of the present invention from skin ageing, preserve moisture, mechanism such as energy supplement sets about, and develops a kind of skin-active composition that simultaneously skin is had defence, maintenance, lifting and multi-efficiencies such as antioxidation, anti-saccharifying.
Summary of the invention
The object of the present invention is to provide a kind of cosmetic composition.
The present invention also aims to provide the method for preparing of this cosmetic composition.
In order to realize the object of the invention, the present invention provides a kind of cosmetic composition.Cosmetic composition of the present invention (promptly; D-3 skin-active composition (DERM-3 Complex)) be to use modern hard-core technology; And take into full account the safe and efficient of active component and mutual supplement with each other's advantages characteristic; Choose three kinds of high-efficiency activated compositions, be prepared into D-3 skin-active composition, skin is had defence, maintenance, lifting and multi-efficiencies such as antioxidation, anti-saccharifying.
Cosmetic composition of the present invention comprises: the Semen Tritici aestivi seed extract of 0.001 weight % to 10.0 weight %; 0.001 the coenzyme Q10 of weight % to 10.0 weight %; 0.001 the hyaluronate sodium of weight % to 10.0 weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
Preferably, cosmetic composition of the present invention comprises: the Semen Tritici aestivi seed extract of 0.001 weight % to 5.0 weight %; 0.001 the coenzyme Q10 of weight % to 5.0 weight %; 0.001 the hyaluronate sodium of weight % to 5.0 weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
More preferably, cosmetic composition of the present invention comprises: the Semen Tritici aestivi seed extract of 0.5 weight %; 0.2 the coenzyme Q10 of weight %; 0.05 the hyaluronate sodium of weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
More preferably, cosmetic composition of the present invention comprises: the Semen Tritici aestivi seed extract of 0.01 weight %; 0.01 the coenzyme Q10 of weight %; 0.001 the hyaluronate sodium of weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
As used herein, term " Semen Tritici aestivi seed extract " is a notion well-known to those skilled in the art, for example can commodity in use Phytoquintescine by name among the present invention TMSemen Tritici aestivi seed extract (available from ISP Vincience company).
In the present invention; Semen Tritici aestivi seed extract Phytoquintescine is a kind of for protecting skin to avoid ambient pressure; Minimizing also prevents skin elasticity from descending and antioxidation, compressive resistance, the defying age oligopeptide of design; Phytoquintescine derives from einkorn (Triticum monococcum L.), is rich in essential amino acid, the less allergy that causes.It has following effect:
1) recovers skin antioxidation balance, reduce the infringement of external environment, the vestige of desalination skin aging skin.When the generation of ROS (active oxygen) equated with decomposition amount, antioxidation reached balance.But be under pressure and when aging, the antioxidation balance is destroyed:
A) pressure: be exposed to the generation that can increase ROS under the pressure continually, destroy the antioxidation balance, cause skin function disorderly.
B) aging: aging be the anti-oxidation protection function further decline, cause the disorder of the unordered accumulation of ROS and skin.
Experiment showed, that Phytoquintescine can significantly strengthen the activity of antioxidase (SOD) and antioxidation hydrogen enzyme (Catalase).
2) reduce cell injury-protein carbonylation, reduce the skin smooth cut and produce
3) anti-glycosylation damage, the protection skin ageing
Glycosylation is that kind of a non-slowly enzyme touches reaction, occurs in the protein to dissociate between the reducing sugars such as amino and glucose.In skin, it is residual that glycosylation produces new AGE (advanced glycosylation end products), and in the protein of intercellular stroma, form crosslinked, this crosslinked be the reason that causes collagen protein hardening and elasticity reduction.In vitro tests shows that the damage that Phytoquintescine can make Methylglyoxal cause reduces 30-33%.
In the present invention, coenzyme Q10 has following effect:
1) makeup energy: coenzyme Q10 is the energy-producing essential thing of human body, makes energy through stimulating mitochondrion.Mitochondrion is just like intracellular slight power plant, and it can make ATP (ATP) makes health produce power, because coenzyme Q10 can promote the energy manufacturing, therefore also just helps burning to change the heat of fat originally into indirectly.
2) antioxidation: coenzyme Q10 has oxidation resistance, and active oxygen is had the powerful effect that stops.
In the present invention, hyaluronate sodium has following effect:
Hyaluronate sodium has brute force to be preserved moisture, efficiently locks the water effect, is the best material of finding at present of occurring in nature moisture retention, is called as ideal nature moisturizing factor, and its theoretical water retention value is up to more than the 1000ml/g.Hyaluronate sodium can change the function of regulating best moisture-holding capacity automatically according to ambient humidity, makes the water content of keratodermatitis remain on best physiological status.In Various Seasonal, under the varying environment humidity, skin all there is very strong moisture-keeping function.With after make the smooth delicacy of skin, pliable and tough and high resilience.
Compositions of the present invention can be processed skin protection cosmetics, lip care cosmetics or cleaning cosmetics.Preferably, said cleaning cosmetics are facial cream agent, clean agent, bath shampoo, shampoo or hair care agent.
The present invention also provides a kind of method for preparing of cosmetic composition, and this method comprises: at first prepare the aqueous solution of Semen Tritici aestivi seed extract, coenzyme Q10 and hyaluronate sodium, then together with the cosmetic conduct and learning on acceptable carrier mix.
Especially, this method is for directly to be mixed with water solution mixture with three kinds of active component.Be specially: in clean beaker or clean stainless steel cask, add a certain amount of purified water; The hyaluronate sodium that adds formula ratio more fully stirs and makes dissolving fully; The coenzyme Q10 that adds formula ratio then fully stirs and makes dissolving fully; The Semen Tritici aestivi seed extract that adds formula ratio at last fully stirs and makes dissolving fully, and sealing is preserved, and is denoted as D-3 skin-active composition, then together with the cosmetic conduct and learning on acceptable carrier mix.
In addition, the present invention provides a kind of method for preparing of cosmetic composition, and this method comprises: prepare the aqueous solution of Semen Tritici aestivi seed extract, coenzyme Q10 and hyaluronate sodium at first respectively, then together with the cosmetic conduct and learning on acceptable carrier mix.
Especially, this method is for to process aqueous solution respectively with three kinds of active component.Be specially: in clean beaker or clean stainless steel cask, add a certain amount of purified water, add the hyaluronate sodium of formula ratio, fully stir and make dissolving fully, sealing is preserved, and is denoted as D-3 skin-active composition 1 (hyaluronic acid solution), and is subsequent use; In clean beaker or clean stainless steel cask, add a certain amount of purified water, add the coenzyme Q10 of formula ratio, fully stir and make dissolving fully, sealing is preserved, and is denoted as D-3 skin-active composition 2 (coenzyme Q10 solution), and is subsequent use.The Semen Tritici aestivi seed extract this as aqueous solution, can be placed in clean beaker or the clean stainless steel cask, sealing is preserved, and is denoted as D-3 skin-active composition 3 (Semen Tritici aestivi seed extract solution), then together with the cosmetic conduct and learning on acceptable carrier mix.
Cosmetic composition of the present invention is the exclusive skin-active material of the up-to-date release of Mentholatum company; Contain three kinds of high-efficiency activated compositions; The effect that skin is had defence, maintenance, lifting: defence: reduce the infringement of external environment to skin; Reduce the skin smooth cut simultaneously and produce, the vestige of desalination skin aging; Maintenance: effectively to resist drying, various skin problem such as low and deep, tired, improve skin maintenance function, it is young to make skin reply; Promote: promote skin elastic force and tension force, make skin more pliable and tougher flexible.
The specific embodiment
Following examples are used to explain the present invention, but are not used for limiting scope of the present invention.
The preparation of embodiment 1 reinforcing gel cream agent of the present invention
Prescription (weight %):
Technology:
1. Phytoquintescine, coenzyme Q10, hyaluronate sodium are processed aqueous solution respectively with a small amount of purified water, subsequent use.
2. water: purified water, glycerol, carbomer are added container, mix, be heated to 75-80 ℃, subsequent use.
3. oil phase: Glyceryl stearate citrate, tristerin, coconut oil ethylhexyl ester, Dermol 105, polydimethyl siloxane fluid are added container, mix, be heated to 75-80 ℃, subsequent use.
4. water and oil phase are mixed, homogenizing 5-10 minute, stop homogenizing then, stir cooling.
5. be cooled to 60 ℃, add the L-arginine, continue to stir cooling.
6. be cooled to 40 ℃, add Methylisothiazolinone, essence, Phytoquintescine solution, coenzyme Q10 solution, sodium hyaluronate solution, continue to stir cooling.
7. be cooled to 28 ℃ of i.e. preparations and obtain the facial cream agent.
The preparation of embodiment 2 reinforcing gel cream agent of the present invention
According to preparing the reinforcing gel cream agent with embodiment 1 identical mode, difference is that the content of Phytoquintescine is that the content of 0.001 weight %, coenzyme Q10 is that the content of 10.0 weight %, hyaluronate sodium is 0.001 weight %.
The preparation of embodiment 3 reinforcing gel cream agent of the present invention
According to preparing the reinforcing gel cream agent with embodiment 1 identical mode, difference is that the content of Phytoquintescine is that the content of 10.0 weight %, coenzyme Q10 is that the content of 0.001 weight %, hyaluronate sodium is 10.0 weight %.
The preparation of embodiment 4 reinforcing gel cream agent of the present invention
According to preparing the reinforcing gel cream agent with embodiment 1 identical mode, difference is that the content of Phytoquintescine is that the content of 0.001 weight %, coenzyme Q10 is that the content of 10.0 weight %, hyaluronate sodium is 10.0 weight %.
The preparation of embodiment 5 reinforcing gel cream agent of the present invention
According to preparing the reinforcing gel cream agent with embodiment 1 identical mode, difference is that the content of Phytoquintescine is that the content of 0.001 weight %, coenzyme Q10 is that the content of 0.001 weight %, hyaluronate sodium is 10.0 weight %.
The preparation of embodiment 6 daily renewal cleanser agent of the present invention
Prescription (weight %):
Figure BSA00000739964400071
Technology:
1. Phytoquintescine, coenzyme Q10, hyaluronate sodium are processed aqueous solution with a small amount of purified water dissolving, subsequent use.
2. water: purified water, glycerol, 1,3 butylene glycol, EDTA-2Na, potassium hydroxide are added container, mix, be heated to 75-80 ℃, subsequent use.
3. oil phase: lauric acid, myristic acid, Palmic acid, stearic acid, glycol distearate are added container, mix, be heated to 75-80 ℃, subsequent use.
4. water and oil phase are mixed, homogenizing 5-10 minute, stop homogenizing then, insulated and stirred 60 minutes begins to cool down then.
5. be cooled to 40 ℃, add Methylisothiazolinone, essence, D-3 skin activating water solution, continue to stir cooling.
6. be cooled to 32 ℃ and promptly get the facial milk cleanser agent.
The preparation of embodiment 7 daily renewal cleanser agent of the present invention
According to preparing the daily renewal cleanser agent with embodiment 6 identical modes, difference is that the content of Phytoquintescine is that the content of 5.0 weight %, coenzyme Q10 is that the content of 0.001 weight %, hyaluronate sodium is 5.0 weight %.
The preparation of embodiment 8 daily renewal cleanser agent of the present invention
According to preparing the daily renewal cleanser agent with embodiment 6 identical modes, difference is that the content of Phytoquintescine is that the content of 0.001 weight %, coenzyme Q10 is that the content of 5.0 weight %, hyaluronate sodium is 0.001 weight %.
The preparation of embodiment 9 daily renewal cleanser agent of the present invention
According to preparing the daily renewal cleanser agent with embodiment 6 identical modes, difference is that the content of Phytoquintescine is that the content of 0.001 weight %, coenzyme Q10 is that the content of 5.0 weight %, hyaluronate sodium is 5.0 weight %.
The preparation of embodiment 10 daily renewal cleanser agent of the present invention
According to preparing the daily renewal cleanser agent with embodiment 6 identical modes, difference is that the content of Phytoquintescine is that the content of 5.0 weight %, coenzyme Q10 is that the content of 0.001 weight %, hyaluronate sodium is 0.001 weight %.
The preparation of embodiment 11 skin-active shower distillate medicinal waters of the present invention
Prescription (weight %):
Figure BSA00000739964400091
Technology:
1. Semen Tritici aestivi seed extract, coenzyme Q10, hyaluronate sodium are processed aqueous solution with a small amount of purified water dissolving, subsequent use.
2. purified water, dodecyl polyethers ammonium sulfate, glycol distearate, citric acid are added a suitable vessel, be heated to 75-80 ℃, mix.
3. add cocoyl CAB, sodium chloride then, mix, begin to cool down.
4. be cooled to 40 ℃, add Methylisothiazolinone, essence, D-3 skin activating water solution, continue to stir cooling.
5. be cooled to 30 ℃ and promptly get skin-active shower distillate medicinal water.
The coating of the reinforcing gel cream agent of experimental example 1 embodiment 1 preparation and the evaluation of use feeling
According to following (a) 5 grades of evaluation criterions, estimate (1) applicability (workability), (2) use feeling (freshness between the operating period), (3) use feeling (not thickness sense) of the reinforcing gel cream agent of embodiment 1 preparation by 10 members of expert group.According to following (b) 4 grades of criterions, use the average mark of the sample that obtains through 5 grades of evaluation criterions to judge.
Figure BSA00000739964400101
Find through (a) 5 grades of evaluation criterion tests:
The mark of applicability (workability) is respectively: 4,4,3,4,2,4,3,4,3,4;
The mark of use feeling (freshness between the operating period) is respectively: 3,4,4,4,3,4,4,3,4,4;
The mark of use feeling (not thickness sense) is respectively: 3,2,4,4,4,4,4,4,4,3.
Find according to (b) 4 grades of criterion tests:
The average mark of applicability (workability) is 3.5, and effect is excellent;
The average mark of use feeling (freshness between the operating period) is 3.7, and effect is excellent;
The average mark of use feeling (not thickness sense) is 3.6, and effect is excellent.
The wrinkle removing Evaluation on effect of the daily renewal cleanser agent of experimental example 2 embodiment 6 preparations
Wrinkle removing effect for the daily renewal cleanser agent of estimating embodiment 6 preparation; The daily renewal cleanser agent of embodiment 6 preparations is spread upon on 10 members' of expert group the skin; Twice of every day; Carried out one month, these experts estimate the wrinkle removing effect of the daily renewal cleanser agent of embodiment 6 preparations according to following (c) 4 grades of evaluation criterions.According to following (d) 4 grades of criterions, use the average mark of the sample that obtains through 4 grades of evaluation criterions to judge.
Figure BSA00000739964400111
Figure BSA00000739964400112
Find through (c) 4 grades of evaluation criterion tests: the mark of wrinkle removing effect is 4,3,4,4,3,4,4,4,3,4; Average mark is 3.7, and effect is excellent.
The evaluation of the freckle effect of the daily renewal cleanser agent of experimental example 3 embodiment 6 preparations
Freckle effect for the daily renewal cleanser agent of estimating embodiment 6 preparation; The daily renewal cleanser agent of embodiment 6 preparations is spread upon on 10 members' of expert group the skin; Twice of every day; Carried out one month, these experts estimate the freckle effect of the daily renewal cleanser agent of embodiment 6 preparations according to following (e) 4 grades of evaluation criterions.According to following (f) 4 grades of criterions, use the average mark of the sample that obtains through 4 grades of evaluation criterions to judge.
Figure BSA00000739964400121
Figure BSA00000739964400122
Find through (e) 4 grades of evaluation criterion tests: the mark of freckle effect is 4,3,3,4,4,4,3,4,4,4; Average mark is 3.7, and effect is excellent.

Claims (8)

1. a cosmetic composition is characterized in that, comprises: the Semen Tritici aestivi seed extract of 0.001 weight % to 10.0 weight %; 0.001 the coenzyme Q10 of weight % to 10.0 weight %; 0.001 the hyaluronate sodium of weight % to 10.0 weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
2. cosmetic composition according to claim 1 is characterized in that, comprises: the Semen Tritici aestivi seed extract of 0.001 weight % to 5.0 weight %; 0.001 the coenzyme Q10 of weight % to 5.0 weight %; 0.001 the hyaluronate sodium of weight % to 5.0 weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
3. cosmetic composition according to claim 2 is characterized in that, comprises: the Semen Tritici aestivi seed extract of 0.5 weight %; 0.2 the coenzyme Q10 of weight %; 0.05 the hyaluronate sodium of weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
4. cosmetic composition according to claim 2 is characterized in that, comprises: the Semen Tritici aestivi seed extract of 0.01 weight %; 0.01 the coenzyme Q10 of weight %; 0.001 the hyaluronate sodium of weight %; With acceptable carrier on the cosmetic conduct and learning of effective dose.
5. according to each described cosmetic composition in the claim 1 to 4, it is characterized in that said compositions can be processed skin protection cosmetics, lip care cosmetics or cleaning cosmetics.
6. cosmetic composition according to claim 5 is characterized in that, said cleaning cosmetics are facial cream agent, clean agent, bath shampoo, shampoo or hair care agent.
7. the method for preparing of a cosmetic composition, this method comprises: at first prepare the aqueous solution of Semen Tritici aestivi seed extract, coenzyme Q10 and hyaluronate sodium, then together with the cosmetic conduct and learning on acceptable carrier mix.
8. the method for preparing of a cosmetic composition, this method comprises: prepare the aqueous solution of Semen Tritici aestivi seed extract, coenzyme Q10 and hyaluronate sodium at first respectively, then together with the cosmetic conduct and learning on acceptable carrier mix.
CN2012102132222A 2012-06-27 2012-06-27 Cosmetic composition and preparation method thereof Pending CN102764209A (en)

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* Cited by examiner, † Cited by third party
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CN111329783A (en) * 2020-03-04 2020-06-26 华熙生物科技股份有限公司 Composition for instantly brightening skin color and application thereof
CN113143823A (en) * 2021-04-28 2021-07-23 段传利 Skin care product for removing and killing mites and preparation method thereof

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CN113143823A (en) * 2021-04-28 2021-07-23 段传利 Skin care product for removing and killing mites and preparation method thereof

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Application publication date: 20121107