KR20210048993A - Hair cosmetic composition comprising Lactobacillus fermentation - Google Patents

Abstract

The present invention relates to a hair cosmetic composition comprising a Lactobacillus fermented product. The Lactobacillus fermented product according to the present invention is a natural product, and can be usefully used as a hair cosmetic composition by showing effects of preventing and alleviating canities.

Description

Hair cosmetic composition comprising Lactobacillus fermentation

The present invention relates to a hair cosmetic composition comprising a Lactobacillus fermented product.

White hair generally occurs as aging progresses, and since it gives a strong impression of old age, many studies have been conducted on dyeing agents that dye white hair black to hide the generated white hair. However, dyeing is a temporary method and must be re-dyed by the growth of white hair, and the oxidizing type black hair dye, which is currently widely used, damages the skin by the use of an oxidizing agent or the like.

In addition, when gray hair occurs, it looks older than the age, styling is difficult, and personal appearance satisfaction is lowered. As a complementary measure for this, a method such as wig, dyeing, or taking medicine can be used, but there are disadvantages of high cost, hassle, and side effects. In particular, in the case of hair dyeing, not only the health of the hair is deteriorated, but also allergic or inflammatory reactions caused by chemicals, and hair loss may be caused. In addition, there is an inconvenience that must be performed periodically, and there is a problem that an unnatural color is often produced.

As the cause of white hair, the loss of stem cells of melanocytes and a decrease in white activity of melanocytes have been proposed. In particular, it is known that white hair caused by aging is mainly caused by the loss of stem cells, and the occurrence of white hair, including marlin, is known to be due to the decrease in the activity of melanocytes due to environmental and mental stress in modern society. The melanin synthesis activity of melanocytes is greatly influenced by the activity of MITF.

As a white hair inhibitor, black sesame seeds, walnut meat, nasturtium, and honey are mixed with Sukjihwang, Cheonmundong, and Maekmundong as auxiliary ingredients. Put it together in a container and boil it at a temperature of 50℃ so that the chemical solution keeps black beans black, using black sesame, black pine leaves, and kelp, using extract of oleander extract, using pituitary hormones, cAMP(3'-5 '-cyclic adenosine monophosphate), vitamin D3, and the like have been disclosed, but the tangible effect has not been exhibited.

Under this background, the present inventors have made great efforts to develop an excellent hair cosmetic composition for preventing white hair and improving alopecia, as a result of researching and confirming that the Lactobacillus fermented product is effective in improving white hair, thereby completing the present invention.

0001) Publication Patent No. 10-2015-0124193 0002) Publication Patent No. 10-2003-0052066

An object of the present invention is to provide a hair cosmetic composition comprising a Lactobacillus fermented product.

Hereinafter, the present invention will be described in more detail.

Meanwhile, each description and embodiment disclosed herein may be applied to each other description and embodiment. That is, all combinations of various elements disclosed herein fall within the scope of the present invention. In addition, it cannot be said that the scope of the present invention is limited by the specific description described below.

In addition, those of ordinary skill in the art can recognize or ascertain using only routine experimentation a number of equivalents to the specific aspects of the invention described in this application. Also, such equivalents are intended to be included in the present invention.

As an aspect of the present invention for solving the above problems, the present invention provides a hair cosmetic composition comprising a Lactobacillus fermented product as an active ingredient.

The term "Lactobacillus fermented product" of the present invention refers to a mixture of fermented products obtained by fermenting a strain of Lactobacillus spp. on a medium containing an energy source such as skim milk powder.

The "fermentation" refers to a process of decomposing organic matter using enzymes possessed by microorganisms.

The term "fermentation" of the present invention refers to a strain obtained by culturing a microorganism in a medium for a certain period of time, a medium containing its metabolites, extra nutrients, and the like, and a culture solution obtained by removing the strain from the medium. Or it may include a concentrate, or a dried product thereof.

The Lactobacillus is Lactobacillus pentosus, Lactobacillus brevis, Lactobacillus plantarum, Lactobacillus casei and Lactobacillus acidophilus It may be one or more selected from the group consisting of, but is not limited thereto.

Specifically, the "lactobacillus fermented product" defined in the present invention is not limited thereto, but may be included in 0.2 to 20% by weight, preferably 0.2 to 10% by weight, more preferably 0.2 to 5 It may be included in weight percent. If the content is less than 0.2% by weight, it is not preferable because the originally desired activity cannot be sufficiently achieved, and if it exceeds 20% by weight, it may be uneconomical because a distinct increase in effect is not expected as much as an increasing content.

For example, the fermentation of Lactobacillus may be performed in a glucose (glucose) or peptone medium at a temperature of 30 to 39° C. for 12 to 120 hours. Specifically, it may be performed at 35° C. for 40 hours, but is not limited thereto. This is because fermentation does not easily occur at temperatures below 30°C, and Lactobacillus bacteria, which are weak to heat, die at temperatures above 39°C. The fermentation of the lactobacillus may be performed, for example, for 12 to 120 hours or for 24 to 72 hours. For example, if the fermentation time is less than 12 hours, the decomposition time of the peptonated proteolytic product may be insufficient, so that the content of the peptide having a low molecular weight may be too small, and if the fermentation time exceeds 120 hours, economic feasibility may be deteriorated.

The lactobacillus fermented product may be a fermented product containing a large amount of carboxyl groups. Specifically, the carboxyl group may be substituted by 50 to 95%, but is not limited thereto. The carboxyl group of the fermentation product reacts with the amino acid inside the hair to change the color of the hair through an external reaction in the hair at room temperature, thereby improving and preventing scratching.

The present invention is a hair cosmetic composition, characterized in that it prevents white hair and improves alopecia.

The composition of the present invention is a hair cosmetic composition, characterized in that it prevents white hair and improves alopecia, and the term "white hair disease" refers to melanocytes in hairs such as hair, eyebrows, and eyelashes. This is the graying and whitening of hair due to the reduction of melanin produced by ). The mechanism of occurrence of alopecia is known to be due to the fact that the number of melanocytes forming melanin pigment in hair follicles decreases, and melanin cannot be transferred to surrounding keratinocytes, resulting in a deficiency of the pigment.

In the present invention, the composition is not particularly limited in formulation, but hair conditioner, hair tonic, hair cream, hair lotion, hair face, hair gel, hair pack, hair massage, hair liquid, hair spray, hair mousse , Treatment, non-aerosol mousse, non-aerosol spray, aerosol mousse, aerosol spray, perm, bleaching agent, shampoo, rinse, shampoo and rinse mixed type, soap, powder and oil. The cosmetic composition of each of these formulations may contain various components that are blended in a conventional cosmetic composition according to the above-described various formulations or suitable for the final purpose, and the types and amounts of these components can be easily selected by those skilled in the art.

In the present invention, the composition may contain other ingredients that are usually blended in cosmetics. At this time, the blending ingredients include fats and oils, moisturizers, emollients, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, fungicides, antioxidants, plant extracts, pH adjusters, alcohols, pigments, fragrances, and blood circulation accelerators. , Cooling agents, limiting agents, purified water, etc. can be used.

In a specific example, as a result of comparing an example in which a shampoo and a serum were prepared by including the fermented product of the present invention as an active ingredient and a comparative example in which a shampoo and a serum were prepared without including the fermented product of lactobacillus, the present invention It was confirmed that the hair cosmetic composition of was effective in improving the gray teeth.

Taken together, the present invention suggests that by including the fermented Lactobacillus as an active ingredient to increase the melanin pigment, it is possible to improve the marlin.

The Lactobacillus fermented product according to the present invention can be usefully used as an active ingredient in a cosmetic composition for preventing white hair and improving alopecia by confirming that it is a natural product and has an effect on improving and preventing white hair.

1 is a photograph showing the results of Experimental Example 2 by applying the composition of the present invention to white and gray hair.
2 is a photograph showing the results of Experimental Example 2 by applying the composition of the present invention to white and gray hair.
3 is a photograph showing the results of Experimental Example 2 by applying the composition of the present invention to Subject 1.
4 is a photograph showing the results of Experimental Example 2 by applying the composition of the present invention to Subject 2.
5 is a photograph showing the results of Experimental Example 2 by applying the composition of the present invention to Subject 3.
6 is a photograph showing the results of Experimental Example 2 by applying the composition of the present invention to Subject 4.

Hereinafter, the present invention will be described in more detail by the following examples. However, the following examples are for illustrative purposes only, and the scope of the present invention is not limited thereto.

Preparation Example 1. Preparation of fermented product of Lactobacillus strain

1.1 Lactobacillus culture

Microorganism seed culture: A strain selected from a total of 4,000 species was used.

The screening period took 10 years.

1.2 Fermentation of culture broth

Lactobacillus culture broth was fermented at 35° C. for 40 hours in glucose (glucose) and peptone medium.

1.3 Fermentation purification

^Two 400 m 2 filters were used twice, and a 200 nm filter was used for the first purification.

The purification time took 36 hours.

1.4 Concentration and acquisition of fermented products

At the initial culture concentration of 20%, more than 76% was obtained after the concentration process through water evaporation for 20 hours.

Preparation Example 2. Preparation of hair shampoo

A hair shampoo was prepared by a conventional method according to the prescription shown in Table 1 below, including the fermented product obtained in Preparation Example 1 of the present invention.

Raw material name weight% Purified water Remaining To 100 EDTA-2Na Appropriate amount PEG-7 Glyceryl cocoate 0.40 Cetrimonium chloride 0.50 Sodium Citrate Appropriate amount Glycerin 1.20 Citric Acid Appropriate amount Cocamidopropyl betaine 4.50 Ammonium laureth sulfate 15.00 Ammonium lauryl sulfate 5.00 Lauramide DEA 1.00 Phenoxyethanol Appropriate amount Sensiva SC-50 Appropriate amount incense Appropriate amount Sodium Chloride 0.30 LACTOBACILLUS
FERMENT 0 to 20.0

Preparation Example 3. Preparation of hair serum

A hair shampoo was prepared by a conventional method according to the prescription shown in Table 2 below, including the fermented product obtained in Preparation Example 1 of the present invention.

Raw material name weight % Purified water Remaining To 100 Glycerin 4.00 Dex-Panthenol 0.25 Sodium Hydroxide Appropriate amount Ethanol 18.00 L-Menthol 0.30 Salicylic Acid 0.25 Solubilizer 1.10 incense Appropriate amount Lactobacillus ferment 0 to 20.0

Comparative Examples 1 and 2 and Examples 1 to 5

The formulations of Comparative Examples 1 and 2 and Examples 1 to 5 were prepared by varying the lactobacillus fermented product in the formulation of Table 1 as shown in Table 3 below.

Raw material name Comparative Example 1 Comparative Example 2 Example 1 Example 2 Example 3 Example 4 Example 5 Purified water Remaining To 100 Balance
To 100 Balance
To 100 Balance
To 100 Balance
To 100 Balance
To 100 Balance
To 100 EDTA-2Na Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount PEG-7 Glyceryl cocoate 0.40 0.40 0.40 0.40 0.40 0.40 0.40 Cetrimonium chloride 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Sodium Citrate Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Glycerin 1.20 1.20 1.20 1.20 1.20 1.20 1.20 Citric Acid Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Cocamidopropyl betaine 4.50 4.50 4.50 4.50 4.50 4.50 4.50 Ammonium laureth sulfate 15.00 15.00 15.00 15.00 15.00 15.00 15.00 Ammonium lauryl sulfate 5.00 5.00 5.00 5.00 5.00 5.00 5.00 Lauramide DEA 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Phenoxyethanol Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Sensiva SC-50 Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount incense Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Sodium Chloride 0.30 0.30 0.30 0.30 0.30 0.30 0.30 LACTOBACILLUS
FERMENT -
0.010
1.00
2.00
5.00
10.00
20.00

Comparative Examples 3 and 4 and Examples 6 to 10

The formulations of Comparative Examples 3 and 4 and Examples 6 to 10 were prepared by varying the lactobacillus fermented product in the formulation of Table 2 as shown in Table 4 below.

Raw material name Comparative Example 3 Comparative Example 4 Example 6 Example 7 Example 8 Example 9 Example 10 Purified water Remaining To 100 Balance
To 100 Balance
To 100 Balance
To 100 Balance
To 100 Balance
To 100 Balance
To 100 Glycerin 4.00 4.00 4.00 4.00 4.00 4.00 4.00 Dex-panthenol 0.25 0.25 0.25 0.25 0.25 0.25 0.25 Sodium Hydroxide Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Ethanol 18.00 18.00 18.00 18.00 18.00 18.00 18.00 L-Menthol 0.30 0.30 0.30 0.30 0.30 0.30 0.30 Salicyclic Acid 0.25 0.25 0.25 0.25 0.25 0.25 0.25 Solubilizer 1.10 1.10 1.10 1.10 1.10 1.10 1.10 incense Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Appropriate amount Lactobcillus Ferment - 0.010 0.50 1.00 5.00 10.00 20.00

Experimental Example 1: White hair improvement evaluation

To conduct comparative evaluation, wet the hair of Comparative Examples 1, 2 and Examples 1 to 5 using lukewarm water, take an appropriate amount and massage the hair and scalp to foam sufficiently, leave for 3 minutes, rinse clean, and dry the hair dryer. After drying the hair by using, Comparative Examples 3 and 4 and Examples 6 to 10 hair serum was sufficiently sprayed onto the hair for absorption, and then dried using a hair dryer.

The experiment period was conducted for at least 4 weeks, and 20 adults with white hairs aged 30 to 60 were studied. To determine the effect, the condition of the scalp and hair was checked under a microscope after the final clinical trial was completed, and the scalp white hair test, visual evaluation, and individual findings of the subject were selected as an evaluation scale and evaluated in 5 steps, and the score was made out of 5 points in units of 1 point. The judgment score was taken as (Table 5), and the results are shown in Table 6 below.

Judgment score Visual evaluation Personal opinion White parameter One weakening weakening increase 2 No change No change No change 3 Slightly improved Slightly improved Slightly reduced 4 Usually improved Usually improved Usually decrease 5 A lot of improvements A lot of improvements Decrease a lot

Judgment score Comparative example
1+3 Comparative example
2+4 Example
1+6 Example
2+7 Example
3+8 Example
4+8 Example
5+8 Visual evaluation 2.2 2.4 4.1 4.2 4.7 4.8 4.8 Personal opinion 2.8 2.9 3.9 4.4 4.9 4.7 4.8 White parameter 2.1 2.2 4.0 4.2 4.8 4.8 4.9 Comprehensive improvement 2.37 2.50 4.00 4.27 4.80 4.76 4.83

Compared with Comparative Examples 1 to 4 in which the Lactobacillus ferment was not added, it was confirmed that the ability to improve white hair was improved as a result of a combination experiment of shampoo Examples 1 to 5 and Serum Examples 6 to 10 to which the fermented product was added. In the case of shampoo or serum in which the weight% of the lactobacillus fermented product was 0.50 or more, the overall improvement evaluation result of white hair was 4 or more. On the other hand, in the case of Example 4+8 and Example 5+8, it was found that the difference in effect from Example 3+8 was insignificant. The above results suggested that when the lactobacillus fermented product exceeded 5% by weight, a distinct effect was not expected to increase as much as the increased content, which could be uneconomical.

Experimental Example 2: White and gray hair swatch test

To conduct the test, moisten the hair with lukewarm water, apply an appropriate amount of shampoo and massage to create a foam, leave for 3 minutes, rinse thoroughly, dry the hair with a dryer, and apply a comparative hair mist sufficiently to the hair. After spraying and absorbing, it was dried using a hair dryer. This was carried out at 8 hour intervals up to 40 times at 8 hour intervals.

As a result, as shown in FIGS. 1 to 6, it was confirmed that the temporary marlin cover was clearly revealed when Example 5+8 was applied, and as the content of the Lactobacillus fermented product exceeded 0.5% by weight, the color change was more pronounced. It was confirmed that it appeared.

Comprising Experimental Examples 1 to 2 of the present invention, it was confirmed that the composition of the present invention is effective in improving and preventing marlin as a natural product, including fermented Lactobacillus, and the fermented Lactobacillus exceeded 0.5% by weight. Accordingly, it was confirmed that the color change provided more pronounced.

From the above description, those skilled in the art to which the present invention pertains will understand that the present invention can be implemented in other specific forms without changing the technical spirit or essential features thereof. In this regard, it should be understood that the embodiments described above are illustrative in all respects and not limiting. The scope of the present invention should be construed as including the meaning and scope of the claims to be described later rather than the above detailed description, and all changes or modifications derived from the equivalent concepts within the scope of the present invention.

Claims (7)

A hair cosmetic composition comprising fermented Lactobacillus as an active ingredient.
The method of claim 1,
The hair cosmetic composition comprising 0.5 to 20% by weight of the fermented Lactobacillus.
The method of claim 1,
The fermentation will be fermented for 24 to 72 hours at 30 to 39 ℃, hair cosmetic composition.
The method of claim 1,
The Lactobacillus is Lactobacillus pentosus, Lactobacillus brevis, Lactobacillus plantarum, Lactobacillus casei and Lactobacillus acidophilus Any one or more selected from the group consisting of, hair cosmetic composition.
The method of claim 1,
The Lactobacillus fermented product is a carboxyl group is 50 to 95% substituted, hair cosmetic composition.
The method of claim 1,
The composition is characterized in that for preventing white hair and improving alopecia, hair cosmetic composition.
The method of claim 1
The formulation of the cosmetic composition is hair conditioner, hair tonic, hair cream, hair lotion, hair face, hair gel, hair pack, hair massage, hair liquid, hair spray, hair mousse, treatment, non-aerosol mousse , Non-aerosol spray, aerosol mousse, aerosol spray, perm, bleaching agent, shampoo, conditioner, shampoo and rinse mixed type, soap, powder, and oil.

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