CN102743433A - Composition for treating dermatitis and symptoms caused by mosquito bites and preparation method thereof - Google Patents
Composition for treating dermatitis and symptoms caused by mosquito bites and preparation method thereof Download PDFInfo
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- CN102743433A CN102743433A CN2012102124813A CN201210212481A CN102743433A CN 102743433 A CN102743433 A CN 102743433A CN 2012102124813 A CN2012102124813 A CN 2012102124813A CN 201210212481 A CN201210212481 A CN 201210212481A CN 102743433 A CN102743433 A CN 102743433A
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Abstract
The invention discloses a composition for treating dermatitis and symptoms caused by mosquito bites and a preparation method thereof. The composition comprises: by mass, 20 to 30 parts of diphenhydramine hydrochloride, 10 to 20 parts of camphor, 60 to 70 parts of peppermint oil and 2 to 3 parts of glycyrrhetinic acid. The preparation method comprises the following steps of 1, crushing and uniformly mixing the raw materials according to the mass ratio to obtain a mixture, and 2, dissolving the mixture as a solute obtained by the step 1 in an ethanol solution having an ethanol concentration of 60 to 65% by stirring to obtain a mixed solution having a mass ratio of 8.2 to 10%, wherein the mixed solution is the composition. The composition can prevent mosquito bites and treat dermatitis caused by mosquito bites. A large amount of experiments prove that the composition has good effects of repelling mosquitos and treating symptoms such as pain and itch, skin redness and swelling, and dermatitis caused by mosquito bites, and is safe and convenient in use.
Description
Technical field
The present invention relates to a kind of composition and method of making the same of treating symptom behind dermatitis and the mosquito bite.
Background technology
Summer, mosquito was more, also was the morbidity season of common dermatitis, and especially the weather conditions of southern high-temperature high humidity make mosquito multiply; A large amount of mosquito proof articles for use have appearred in the life, such as floral water etc., and can expelling mosquito; But can't alleviate because symptoms such as the caused dermatitis of mosquito bite or papular urticarias, but people are usually to the use of floral water mistake, behind mosquito bite in the life; Directly smear floral water at the place of biting, recuperate under medical treatment by a certain percentage and form, bite though have mosquito proof because floral water is some Chinese crude drugs and spice; The effect of calming the nerves, but Diazolidinyl Urea directly smeared on the skin; Responsive skin matter causes allergy easily, and especially skin such as infant uses floral water very easily skin to be caused damage.The medicament that has also occurred symptom behind some treatment mosquito bite simultaneously in the life, but XILEI SAN or antiinflammatory and analgesic paste etc., but this type drug use inconvenience also can't play the effect of prevention mosquito bite.Therefore in the actual life, the drug product of the symptom that occurs behind prevention mosquito bite and the treatment mosquito bite is relatively more rare, needing to demand urgently the summer that mosquito multiplies such can preventing mosquito bite, can treat the medicine that occurs symptom behind the mosquito bite again.
Summary of the invention
The object of the present invention is to provide a kind of composition and method of making the same of treating symptom behind dermatitis and the mosquito bite, it has the prevention mosquito bite, the symptom that occurs behind the treatment mosquito bite, and easy to use.
The present invention realizes like this; A kind of composition and method of making the same of treating symptom behind dermatitis and the mosquito bite; It is characterized in that said compositions by the quality proportioning is: diphhydramine hydrochloride 20-30 part, Camphora 10-20 part, Oleum menthae 60-70 part and enoxolone 2-3 part; Described method for preparing may further comprise the steps: 1) pulverize mix homogeneously by the quality proportioning of compositions; Obtain mixture, 2) get the alcoholic solution that alcohol concentration is 60-65%, with alcoholic solution as solvent; With the mixture that obtains in the step 1) as solute; After the stirring and dissolving, finally obtain quality, promptly get product very than being the mixed solution of 8.2-10%.
Technique effect of the present invention is: the present invention can not only prevent mosquito bite; Can also treat the scytitis of the appearance behind the mosquito bite; Through a large amount of experiments; Prove its good mosquito dispersing effect and treated the symptoms such as sufferings, red swelling of the skin and dermatitis that occur behind the mosquito bite, safety easy to use.
The specific embodiment
Through embodiment the present invention is done further elaboration below,
Embodiment one, get diphhydramine hydrochloride 21g, Camphora 10g, Oleum menthae 66g and enoxolone 2g; After pulverizing mixing to above-mentioned composition in proportion earlier; Be dissolved into alcohol concentration and be in 60% the alcoholic solution, finally make quality very than the mixed solution that is 8.5%.
Embodiment two, get diphhydramine hydrochloride 25g, Camphora 12g, Oleum menthae 60g and enoxolone 2.5g; After pulverizing mixing to above-mentioned composition in proportion earlier; Be dissolved into alcohol concentration and be in 62% the alcoholic solution, finally make quality very than the mixed solution that is 9.2%.
Embodiment three, get diphhydramine hydrochloride 29g, Camphora 18g, Oleum menthae 62g and enoxolone 2.8g; After pulverizing mixing to above-mentioned composition in proportion earlier; Be dissolved into alcohol concentration and be in 64% the alcoholic solution, finally make quality very than the mixed solution that is 9.8%.
The mosquito dispersing contrast test is following, random choose 100 subjects, with the left and right sides arm of the experimental subject ratio of opposing; In this 100 routine subjects, wherein an arm is not taked any mosquito dispersing measure, and an other arm is smeared a kind of mixed solution that obtains of embodiment; After 8 hours, by inquiry, do not take the arm of mosquito proof measure to have 89 examples to receive mosquito bite in 100 examples; Erubescence swell and itch symptom behind the appearance mosquito bite; Smear the arm of mixed solution in other 100 examples, only have 2 examples the symptom of mosquito bite to occur, the inventor to the summary of test data is: choosing object all is at random; Because two arms of a people are in the identical environment basically; Therefore the test data that draws has the scientific basis of very strong comparative fully, and the arm that does not have safeguard procedures up to 89%, is merely 2% and be coated with the ratio of being bitten of the present invention by the ratio of mosquito bite.
The test of scytitis behind the treatment mosquito bite; 100 people at random, the experimenter all has the red and swollen symptom of the skin sufferings that occurred behind the mosquito bite, and the inventor is in order to prove absolutely effect of the present invention; Be divided into two contents to test; Among the first, the 100 routine experimenter, red and swollen position after it is by mosquito bite, occurs and smear the mixed solution that embodiment two obtains; Among the second, the 100 routine experimenter, smear the mixed solution that embodiment two obtains at its healthy skin place.About 10 minutes, 100 routine experimenters all represent the obviously elimination of sufferings sensation, observe its affected part at last, and red and swollen phenomenon is obviously eliminated; In 60 minutes, observe the healthy skin place that 100 routine experimenters are coated with embodiment two mixed solutions and irritated red and swollen phenomenon do not occur, the experimenter representes not occur the zest sensation simultaneously, and the experimenter also representes the use initial stage, and the refreshing sensation of refrigerant ice is only arranged.
As everyone knows, the ethanol of high concentration can make protein denaturation, has the sterilizing effect; If alcohol concentration is higher than 70%; Will produce zest sensation to skin, and along with the increase of alcohol concentration, the zest of ethanol is big more; Therefore in order to reduce the skin allergy that ethanol possibly cause, the concentration that reduces ethanol is effective and efficient manner; Diphhydramine hydrochloride is claimed benadryl again, can eliminate various allergic symptoms, and its central inhibitory action is remarkable, still has calmness, anti-cinetosis and antiemetic effect, is used for various allergic skin diseases, like urticaria, insect bite disease; Enoxolone is the natural extract of Radix Glycyrrhizae; Enoxolone is structurally similar with hydrocortisone, is used for various treating for skin disease, and enoxolone is classical anti-inflammatory drug; The immunologic function of scalable skin; Strengthen the resistance against diseases of skin, diminish inflammation, Polyglucan, cleaning skin, can also remove the toxic and side effects of other factors simultaneously skin; Camphora is applied to skin has gentle stimulation and antisepsis, and refrigerant sense is arranged, and it also has slight local anesthesia effect, can be used as local anti-inflammatory and antipruritic varnish clinically, has killing parasites for relieving itching; The effect of reducing swelling and alleviating pain, simultaneously Camphora mosquito dispersing effect is remarkable, and Mentholum has refrigerant itching relieving effect, and the Oleum menthae in the Mentholum not only can be driven away mosquito, and effective kill mosquitoes larva.Camphora uses with Mentholum simultaneously, can significantly improve the effect of anti-inflammatory anti-itch, has also improved the effect of mosquito dispersing.
Claims (2)
1. a composition and method of making the same of treating symptom behind dermatitis and the mosquito bite is characterized in that said compositions by the quality proportioning is: diphhydramine hydrochloride 20-30 part, Camphora 10-20 part, Oleum menthae 60-70 part and enoxolone 2-3 part.
2. as claimed in claim 1 a kind of treat dermatitis and mosquito bite cause and the composition and method of making the same of symptom it is characterized in that described method for preparing may further comprise the steps: 1) pulverize mix homogeneously by the quality proportioning of compositions; Obtain mixture, 2) get the alcoholic solution that alcohol concentration is 60-65%, with alcoholic solution as solvent; With the mixture that obtains in the step 1) as solute; After the stirring and dissolving, finally obtain quality, promptly get product very than being the mixed solution of 8.2-10%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102124813A CN102743433A (en) | 2012-06-26 | 2012-06-26 | Composition for treating dermatitis and symptoms caused by mosquito bites and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2012102124813A CN102743433A (en) | 2012-06-26 | 2012-06-26 | Composition for treating dermatitis and symptoms caused by mosquito bites and preparation method thereof |
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| CN102743433A true CN102743433A (en) | 2012-10-24 |
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| CN2012102124813A Pending CN102743433A (en) | 2012-06-26 | 2012-06-26 | Composition for treating dermatitis and symptoms caused by mosquito bites and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142619A (en) * | 2013-03-01 | 2013-06-12 | 邵武市美菰林卫生用品有限公司 | Pharmaceutical composition for treating dermatitis and preparation method thereof |
| CN104825353A (en) * | 2015-04-30 | 2015-08-12 | 柳州立洁科技有限公司 | Infant reddish sudamen scream |
| CN105534849A (en) * | 2015-12-30 | 2016-05-04 | 耿威 | Chicken embryo peptide as well as preparation method and application thereof in preparation of anti-inflammation, acne removal and black hair generation products |
| CN108295105A (en) * | 2018-04-09 | 2018-07-20 | 广东工业大学 | The new application of Yi Zhong le dish extracts |
-
2012
- 2012-06-26 CN CN2012102124813A patent/CN102743433A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142619A (en) * | 2013-03-01 | 2013-06-12 | 邵武市美菰林卫生用品有限公司 | Pharmaceutical composition for treating dermatitis and preparation method thereof |
| CN103142619B (en) * | 2013-03-01 | 2014-09-17 | 邵武市美菰林卫生用品有限公司 | Pharmaceutical composition for treating dermatitis and preparation method thereof |
| CN104825353A (en) * | 2015-04-30 | 2015-08-12 | 柳州立洁科技有限公司 | Infant reddish sudamen scream |
| CN105534849A (en) * | 2015-12-30 | 2016-05-04 | 耿威 | Chicken embryo peptide as well as preparation method and application thereof in preparation of anti-inflammation, acne removal and black hair generation products |
| CN105534849B (en) * | 2015-12-30 | 2018-11-20 | 耿威 | A kind of chicken embryo peptide and preparation method thereof and the application in preparation anti-inflammatory, anti-acne, the regenerated product of dark hair |
| CN108295105A (en) * | 2018-04-09 | 2018-07-20 | 广东工业大学 | The new application of Yi Zhong le dish extracts |
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Application publication date: 20121024 |