CN111773341A

CN111773341A - Compound Chinese herbal medicine external preparation for treating piglet mange

Info

Publication number: CN111773341A
Application number: CN202010838285.1A
Authority: CN
Inventors: 赵强; 杨劝生
Original assignee: Tianshui Normal University
Current assignee: Tianshui Normal University
Priority date: 2020-08-19
Filing date: 2020-08-19
Publication date: 2020-10-16

Abstract

The invention discloses a compound Chinese herbal medicine external preparation for treating piglet mange, which is prepared by the following steps: weighing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur, Alumen and oleum Lini respectively; respectively pulverizing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur and Alumen, mixing, adding oleum Lini, mixing, and making into soft extract. The external preparation is prepared from all natural Chinese herbal medicines, is used for treating the piglet mange tinea, has no toxic or side effect, and is safe and effective. The compound prescription is prepared, the medicine is applied and smeared for 3-5 days in the daytime and at night, and the total effective rate reaches more than 98 percent.

Description

Compound Chinese herbal medicine external preparation for treating piglet mange

Technical Field

The invention belongs to the technical field of traditional Chinese veterinary medicines, and relates to a compound Chinese herbal medicine external preparation for treating piglet mange.

Background

The tinea waiting is recorded: the dermatosis and the gizzard of the skin and the flesh are gradually growing, or round or oblique, itching and pain are in the form of check, such as the internal parasites and the juice of scratching. Scabies is commonly called scabies and is a chronic parasitic disease of the skin, and the whole growth period of the body from egg to adult is about 10 days, and the growth period is long. Scabies usually originate in the head, cheeks and ears and spread later to the back, sides of the trunk and inside the hind limbs. Local itching of pigs usually occurs by scratching the limbs or rubbing against the corners of the wall or the column. After several days, needle-sized nodules appear on the affected skin, followed by the formation of blisters or pustules. When the blisters and pustules break open, they form crusts. If the disease is serious, the body hair will fall off. The skin has increased keratinization, dryness, wrinkles or chaps, loss of appetite, growth retardation, gradual thinning, and even death. The piglets are weak and the disease is contagious and has strong repeatability, so effective prevention and treatment measures must be taken. At present, most of medicines and methods for treating the mange diseases of the piglets are quick kill, enemy kill, linden missible oil, trichlorfon and the like, or even medicines forbidden to treat the mange diseases are available such as Liuliu powder and the like, but the medicines have great toxic and side effects and cause poisoning problems due to licking of the piglets. Although most western medicines can take effect quickly after treatment, the diseases are easy to relapse, have large side effects and are difficult to eradicate after the medicines are stopped. According to traditional Chinese medicine, tinea corporis is caused by pathogenic wind, dampness, which can affect the striae of skin and muscle or contact with unclean substances. Therefore, a natural medicine for treating the piglet scabies, which has the advantages of high curative effect, safety, reliability, low price and convenient use, needs to be prepared.

Disclosure of Invention

The invention aims to provide a compound Chinese herbal medicine external preparation for treating piglet mange, which has the advantages of high curative effect, safety, reliability, low price and convenient use.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a compound Chinese herbal medicine external preparation for treating piglet mange diseases is prepared by the following steps:

1) respectively weighing 50-60 g of large cherry leaf, 20-30 g of pepper, 10-15 g of radix stemonae, 10-15 g of shrubalthea bark, 10-15 g of sulfur, 4-6 g of alum and 80-100 g of linseed oil;

2) respectively pulverizing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur and Alumen into powder with particle diameter of 90 μm or less, and mixing to obtain mixed medicinal powder;

3) adding oleum Lini into the mixed medicinal powder, concocting into paste to obtain soft extract, and making into compound Chinese herbal medicine external preparation for treating piglet scabies.

The medicinal performance of each component in the compound Chinese herbal medicine external preparation of the invention is as follows:

1. big cherry leaf: clearing away heat and toxic material, eliminating swelling, relieving pain, killing bacteria, and removing skin sore.

2. Chinese prickly ash: sterilizing, disinfecting, relieving pain, relieving itching and swelling.

3. Stemona root: it can be used for treating head louse, body louse, enterobiasis, and pudendum pruritus.

4. And (3) shrubalthea bark: killing parasites and curing tinea.

5. Sulfur: can be used for treating scabies, tinea pedis, carbuncle of yin type, and malignant boil.

6. Alum: detoxify, kill parasites, dry dampness and relieve itching.

7. Linseed oil: tinea, eczema, excipient.

The big cherry leaf is the leaf of big cherry of Rosaceae, is sweet, flat and nontoxic (compendium of materia Medica), is pungent and bitter in taste, warm in nature and nontoxic, enters liver and spleen channels, and is mainly used for warming stomach, invigorating spleen, stopping bleeding and detoxifying. It is indicated for stomach cold, food stagnation, diarrhea, hematemesis, and sore. Researches show that the large cherry leaf is rich in bacteriostatic volatile oil, polysaccharide and flavonoid compounds, the minimum bacteriostatic concentration (MIC) of the extract on staphylococcus aureus and escherichia coli is 0.1056mg/mL and 0.1862mg/mL respectively, the 50000-time transmission electron microscope observation shows that the large cherry leaf extract has a destructive effect on the cell structure of bacteria, so that cell membranes are not layered clearly, liquid overflows from the periphery, bacterial fragments lacking any intracellular structures can be observed, and the antibacterial effect is obvious. The compound Chinese herbal medicine external preparation for treating the piglet scabies is prepared by using the functions of sterilizing and diminishing inflammation of the large cherry leaves and treating carbuncle furuncle and the like and matching Chinese herbal medicines with the antibacterial and anti-inflammatory effects of pepper, radix stemonae, sulfur, alum, linseed oil and the like.

The Chinese herbal medicine compound external preparation is compounded according to the Chinese veterinary medicine theory and the inherent properties of Chinese herbal medicines such as large cherry leaves and the like for resisting bacteria and killing insects. Wherein the monarch drug is big cherry leaf, and has effects of sterilizing and removing sore toxin; the ministerial drugs are pepper, stemona root and shrubalthea bark, and have the effects of clearing heat, relieving itching and removing lice; the adjuvant is sulfur, and has effects of removing scabies, tinea and tinea capitis; the guiding drug is alum, and has the effects of detoxifying, killing parasites, eliminating dampness and relieving itching.

The medicine composition has the effects of resisting bacteria, killing insects, detoxifying and relieving itching. Is suitable for external treatment of various scabies, and particularly has more obvious effects on symptoms such as itchiness, dandruff increase, inflammation and the like of the skin of the piglets caused by tinea corporis.

The compound Chinese herbal medicine external preparation of the invention has the usage and dosage that: dipping with cotton swab during the day, and applying to affected part several times a day. Dipping with cotton swab at night, and applying to affected part for 1 time.

The compound Chinese herbal medicine external preparation is prepared from all natural Chinese herbal medicines and is used for treating piglet mange. Has no toxic and side effects, and is safe and effective. The compound prescription is prepared, the medicine is applied and smeared for 3-5 days in the daytime and at night, and the total effective rate reaches more than 98 percent.

Detailed Description

In order to better understand the invention, the results of the curative effect of the drug formula on the piglets suffering from the mange ringworm disease are described below, the new application of the drug formula in the field of Chinese herbal medicine pharmacy is described, and the experimental method and the results are as follows.

Example 1

Respectively weighing 50g of naturally dried large cherry leaf, 20g of pepper, 10g of radix stemonae, 10g of shrubalthea bark, 10g of sulfur, 4g of alum and 80g of linseed oil; pulverizing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur and Alumen into powder with particle size of 90 μm or less, mixing, adding oleum Lini, and concocting into soft extract to obtain compound Chinese herbal medicine external preparation for treating piglet scabies.

Curative effect comparison test: 50 20-day-old piglets suffering from mange ringworm and weighing about 5kg are selected, randomly divided into 5 groups of 10 piglets each, and treated by different treatment preparations: group 1, the compound Chinese herbal medicine external preparation of the invention is used for treatment, and the patient is externally rubbed with a cotton swab for 3 times in the daytime. Group 2, the compound Chinese herbal medicine external preparation of the invention is used for treatment, and the patient is externally rubbed with a cotton swab for 1 time only at night. Group 3, the compound Chinese herbal medicine external preparation of the invention is used for treatment, and cotton swabs are externally applied to the affected part for 3 times in the daytime and 1 time at night. Group 4, the decoction of large cherry leaves with crude drug concentration of 20% is applied externally to the patient 3 times a day. Group 5, the affected part was smeared with tap water 3 times a day as a control. The results are shown in Table 1.

TABLE 1 therapeutic effect of the compound Chinese herbal medicine external preparation of the present invention on the mange of piglets

As can be seen from Table 1, the compound Chinese herbal medicine external preparation is applied and administrated in the daytime and at night, has a remarkable treatment effect on the mange of the domestic piglets, and can be cured within 3-5 days generally.

The clinical curative effect is as follows: 100 piglets suffering from the mange diseases are treated in a flourishing pig farm in Gansu province, Gansu province and valley in 3 months to 2020 and 6 months in 2019, and the compound Chinese herbal medicine external preparation is used for clinical treatment of the mange diseases of the piglets. The medicine is prepared by single compound prescription, is applied and smeared for treatment in the daytime, and is healed after 6-8 days, and the total effective rate reaches 90 percent; the compound prescription is prepared, the medicine is applied and applied for treatment in the daytime and at night, the disease is cured within 3-5 days, and the total effective rate reaches more than 98%. The treatment time, the cost and other factors are combined, 5 days are selected as a treatment course, and the treatment effect is most obvious.

Example 2

Respectively weighing 55g of naturally dried large cherry leaf, 25g of pepper, 12g of radix stemonae, 12g of shrubalthea bark, 12g of sulfur, 5g of alum and 90g of linseed oil; respectively pulverizing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur and Alumen into powder with particle size of 90 μm or less, mixing, adding oleum Lini, and concocting into soft extract to obtain compound Chinese herbal medicine external preparation for treating piglet scabies.

Example 3

Respectively weighing 60g of naturally dried large cherry leaves, 30g of pepper, 15g of radix stemonae, 15g of shrubalthea bark, 15g of sulfur, 6g of alum and 100g of linseed oil; respectively pulverizing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur and Alumen into powder with particle size of 90 μm or less, mixing, adding oleum Lini, and concocting into soft extract to obtain compound Chinese herbal medicine external preparation for treating piglet scabies.

Claims

1. A compound Chinese herbal medicine external preparation for treating piglet mange is characterized in that the compound Chinese herbal medicine external preparation is prepared by the following steps:

1) weighing 50-60 g of large cherry leaf, 20-30 g of pepper, 10-15 g of radix stemonae, 10-15 g of shrubalthea bark, 10-15 g of sulfur, 4-6 g of alum and 80-100 g of linseed oil;

2) respectively pulverizing folium Pruni Pseudocerasi, fructus Zanthoxyli, radix Stemonae, cortex Hibisci, Sulfur and Alumen, and mixing to obtain mixed medicinal powder;

3) adding linseed oil into the mixed medicinal powder obtained in the step 2), mixing into paste, and preparing into a compound Chinese herbal medicine external preparation for treating the piglet mange sickness.

2. The compound Chinese herbal medicine external preparation for treating the piglet scabies according to claim 1, wherein in the step 2), the large cherry leaf, the pepper, the stemona root, the shrubalthea bark, the sulfur and the alum are respectively crushed into powder with the particle size of less than or equal to 90 μm.