CN102731333B - 一种丁卡因的制备方法 - Google Patents
一种丁卡因的制备方法 Download PDFInfo
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- CN102731333B CN102731333B CN201210242596.7A CN201210242596A CN102731333B CN 102731333 B CN102731333 B CN 102731333B CN 201210242596 A CN201210242596 A CN 201210242596A CN 102731333 B CN102731333 B CN 102731333B
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CN201210242596.7A CN102731333B (zh) | 2012-07-13 | 2012-07-13 | 一种丁卡因的制备方法 |
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CN102731333A CN102731333A (zh) | 2012-10-17 |
CN102731333B true CN102731333B (zh) | 2014-12-03 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105646259A (zh) * | 2014-11-18 | 2016-06-08 | 上海朝晖药业有限公司 | 高纯度4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯盐酸盐的制备方法 |
CN106518697A (zh) * | 2016-09-20 | 2017-03-22 | 北京万全德众医药生物技术有限公司 | 一种制备盐酸丁卡因的方法 |
CN109180511A (zh) * | 2018-08-22 | 2019-01-11 | 辽宁东科药业有限公司 | 一种盐酸丁卡因的制备方法 |
CN109761835B (zh) * | 2018-12-29 | 2021-10-15 | 常州市阳光药业有限公司 | 盐酸丁卡因的制备方法 |
CN115466190A (zh) * | 2021-10-13 | 2022-12-13 | 浙江孚诺医药股份有限公司 | 一种丁卡因的制备方法及其应用 |
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2012
- 2012-07-13 CN CN201210242596.7A patent/CN102731333B/zh active Active
Non-Patent Citations (5)
Title |
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A NEW METHOD OF DICAINE SYNTHESIS FROM p-NITROBENZOIC ACID ETHYLATE;M. G. Abdullaev;《Pharmaceutical Chemistry Journal》;20020131;第36卷(第1期);第28-31页 * |
M. G. Abdullaev.A NEW METHOD OF DICAINE SYNTHESIS FROM p-NITROBENZOIC ACID ETHYLATE.《Pharmaceutical Chemistry Journal》.2002,第36卷(第1期), * |
Medicinal Chemistry Letters》.2007,第18卷 * |
Timothy Strassmaier et al..Block of cyclic nucleotide-gated channels by tetracaine derivatives: Role of apolar interactions at two distinct locations.《Bioorganic & Medicinal Chemistry Letters》.2007,第18卷 * |
Timothy Strassmaier et al..Block of cyclic nucleotide-gated channels by tetracaine derivatives: Role of apolar interactions at two distinct locations.《Bioorganic & * |
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Effective date of registration: 20190222 Address after: 253100 North Second Ring Road, West First Road, Dezhou Plain Economic Development Zone, Shandong Province Patentee after: Shandong Yunjia Pharmaceutical Co. Ltd. Address before: 250101 2350 development road, hi tech Development Zone, Ji'nan, Shandong Patentee before: Jinan Chenghui Shuangda Chemical Co., Ltd. |
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Denomination of invention: A preparation method of tetracaine Effective date of registration: 20220616 Granted publication date: 20141203 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |
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