CN102698012B - Externally applied traditional Chinese medicine for treating oral lichen planus - Google Patents
Externally applied traditional Chinese medicine for treating oral lichen planus Download PDFInfo
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- CN102698012B CN102698012B CN201210148194.0A CN201210148194A CN102698012B CN 102698012 B CN102698012 B CN 102698012B CN 201210148194 A CN201210148194 A CN 201210148194A CN 102698012 B CN102698012 B CN 102698012B
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- 239000003814 drug Substances 0.000 title claims abstract description 34
- 206010030983 oral lichen planus Diseases 0.000 title claims abstract description 11
- 239000000843 powder Substances 0.000 claims abstract description 6
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 5
- 239000009286 sanguis draxonis Substances 0.000 claims description 4
- 241000545442 Radix Species 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 10
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- 229910021538 borax Inorganic materials 0.000 abstract description 2
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- 239000003440 toxic substance Substances 0.000 description 3
- 208000007117 Oral Ulcer Diseases 0.000 description 2
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- 244000179560 Prunella vulgaris Species 0.000 description 1
- 241000219780 Pueraria Species 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to the field of a traditional Chinese medicine, in particular to an externally applied traditional Chinese medicine for treating oral lichen planus, which is prepared from the following raw material medicines by weight parts: 30g of radix astragali, 15g of radix zanthoxyli, 5g of resina draconis, 15g of borax, 1g of cinnabar and 2g of radix glycyrrhizae; and the medicines are ground and screened by a screen of 100-120 meshes to obtain fine powder, and then the fine powder is filled into a bottle to further use after being sterilized at high temperature. According to the externally applied traditional Chinese medicine, the local drug delivery is carried out, the function is direct and both principal and secondary aspects of disease are treated, so that the externally applied traditional Chinese medicine has the characteristics of short course of treatment, definite curative effect and uneasy relapse; and the cure rate reaches up to 89.29% and the effective ratio reaches up to 96.25%.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of external application Chinese medicine for the treatment of oral lichen planus.
Background technology
Oral lichen planus is a kind of betide oral mucosa and agnogenic chronic shallow change of the keratinization sexually transmitted disease (STD) in property inflammation of skin.The typical case in oral cavity shows as pearly-lustre white stripes and interweaves, extends, and forms the mucosal injury of the variforms such as bar rope, netted, dendroid, ring-type and speckle shape.Its sickness rate is about 0.51%.Patient feels oral cavity partial causalgia, gargalesthesia, coarse, rotten to the corn, impact feed.Doctor trained in Western medicine is thought may be relevant with (1) Nervous and Mental Factors, (2) endocrine factors, (3) immune factor, (4) infective agent, (5) microcirculation disturbance factor, (6) inherited genetic factors etc.; The traditional Chinese medical science thinks that oral lichen planus is many because of internal injury caused by excess of seven emotions, plain body weakness, the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, cause hot and suffocating, hyperactivity of deficient fire stifling and send out.At present clinically, western medical treatment adopts antiinflammatory antibiotic to treat more, this therapy instant effect, but side effect is very big, easily makes Relapse rate, can not eradicate.
Summary of the invention
The present invention is directed to prior art deficiency, provide a kind of evident in efficacy, and the external application Chinese medicine of the treatment oral lichen planus having no side effect.
Technical scheme of the present invention is: a kind of external application Chinese medicine for the treatment of oral lichen planus, is characterized in that it is comprised of the material medicine of following weight: 30 grams of the Radixs Astragali, 15 grams of Radix Zanthoxylis, 5 grams of Sanguis Draxonis, 15 grams of Boraxs, 1 gram, Cinnabaris, 2 grams, Radix Glycyrrhizae; Said medicine was ground to 100～120 mesh sieves and obtain fine powder, high temperature sterilize processing packs in bottle standby.
Pharmacology analysis: the Radix Astragali sweet in the mouth in the present invention, slightly warm in nature.Return lung, spleen, liver, kidney channel.There is the effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, tonifying the lung spleen invigorating, wind dispelling fortune poison, inducing diuresis to remove edema; Radix Zanthoxyli bitter in the mouth, pungent, property is flat; Slightly poisonous.Return liver, stomach warp.There are promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, the effect of dispelling wind and removing obstruction in the collateral.Borax sweet in the mouth, salty, cool in nature.Attach to the lung and stomach meridians.External heat-clearing and toxic substances removing, detumescence, anticorrosion; Sanguis Draxonis sweet-salty, property is flat.Enter the heart, liver, spleen channel.External hemostasia and promoting granulation, sore.Cinnabaris is sweet, is slightly cold, slightly poisonous; GUIXIN warp; Have clear away heart-fire relieving convulsion, the detoxicating functions of calming the nerves.Radix Glycyrrhizae property is flat, and sweet in the mouth, returns 12 warps.Have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic be so that the pharmacological action such as anticancer.Above Chinese medicine, mutually collaborative, given prominence to sore hemostasia and promoting granulation, heat-clearing and toxic substances removing, the effect of the silt pain relieving of dispelling, spleen reinforcing lung moistening.
The present invention is take removing the necrotic tissue and promoting granulation, yin nourishing detoxicating, function of spleen and stomach regulating, strengthening vital QI to eliminate pathogenic factors as Therapeutic Principle.This medicine external directly acts on affected part, absorbs soon, and nonirritant, pain relieving is fast, and pain relieving in 10 minutes after medication, can fully recover for 3-5 days, and effective percentage reaches 96.25%, and cure rate reaches 89.29%.
The specific embodiment:
Embodiment 1: a kind of external application Chinese medicine for the treatment of oral lichen planus, its material medicine by following weight forms: 30 grams of the Radixs Astragali, 15 grams of Radix Zanthoxylis, 5 grams of Sanguis Draxonis, 15 grams of Boraxs, 1 gram, Cinnabaris, 2 grams, Radix Glycyrrhizae; Said medicine was ground to 100～120 mesh sieves and obtain fine powder, high temperature sterilize processing packs in bottle standby.
Every day 3 times, is directly applied to affected part, oral cavity by Chinese medicine fine powder after meal, or with Oleum sesami, is adjusted to pasty state and is applied to affected part, oral cavity, and being used in conjunction 3-5 days can cure.
The present invention treats the external application Chinese medicine clinical efficacy of oral lichen planus and sums up:
Clinical treatment observation 56 people, wherein male 27 people, age 18-50 year, female 29 people, age 16-49 year.
One, clinical diagnosis Signs: oral mucosa and lingual margin, the tip of the tongue initial stage SHENGHUANG white ulcer point that differs in size, then there is ulcer, erosion, there is yellow pseudomembrane on surface, edge blush pain, number single-shot or multiple, light disease 7-10 days, serious symptom does not heal all the year round, and has periodical attack.
Two, medication and dosage: medicine of the present invention, be directly applied to affected part or be adjusted to pasty state with Oleum sesami and be applied to affected part, oral cavity, with medicine, cover trouble face and be as the criterion, three times on the one, medication behind its chamber of gargling clearly after meal, best results.
Three, efficacy assessment standard:
Cure: transference cure;
Effective: symptom is obviously improved;
Effective: symptom has larger improvement;
Invalid: symptom is without improvement.
Four, therapeutic effect: the present invention organically combines convergence granulation promoting, detoxicating, relieving inflammation, reducing swelling and alleviating pain, reparation mucosa, local application, effect is direct, treating both the principal and secondary aspects of a disease, thereby there is short treating period, determined curative effect, the difficult feature recurring, through 56 routine patients are treated to observation, cure 50 examples, cure rate reaches 89.29%, invalid 2 examples, account for 3.57%, effective percentage reaches 96.25%.
Five, model case:
1, Pueraria lobota × ×, man, 48 years old, oral cavity pain, took food difficult one week, took stomatocase-treating capsule treatment and had no improvement.Check that respectively there is 2 × 2mm visible tongue both sides
2large aphtha, surperficial HUANGBAI(sic), around there is 3 × 3mm slightly red right cheek inner side
2large aphtha, with every day of the present invention 3 times, after 24 hours, pain relief can be taken food, and within 48 hours, ulcer is dwindled, and connects and is coated with medication recovery from illness in 5 days.Follow up a case by regular visits to and within 1 year, have no recurrence.
2, Yan, female, 35 years old, the oral ulcer of repeatedly showing effect over 3 years, recurrence period 2-5 month is not etc., once arrived many hospital therapies, took multi-medicament, still frequently outbreak, has area 0.21cm × 0.5cm ulcer 3 places while treating with the present invention, be coated with 12 recoveries from illness of medicine of the present invention, follow up a case by regular visits to 8 months without recurrence.
3, Zhang, man, 22 years old, during treatment, there are area 0.2cm × 0.3cm ulcer 3 places, with 9 (3 days) recoveries from illness of medicine of the present invention, follow up a case by regular visits to June without recurrence.
4, Wu, female, 49 years old, suffer from oral ulcer 10 years, whenever fever, mistake eye, fatigue show effect, oral cavity pain during outbreak, eat badly, not sleep well, check and see that end opening disgrace inner side mucosa has the large aphtha of a diameter 6mm, inside left cheek, mucosa has the large aphtha of a diameter 4mm, congested, local pain around, and ulcer surface has yellow-white pseudomembrane, affected part is coated with medicine of the present invention, pain relieving in 3 days, recovery from illness in 8 days, follows up a case by regular visits to and within 2 years, has no recurrence.
Claims (1)
1. treat an external application Chinese medicine for oral lichen planus, it is characterized in that it is comprised of the material medicine of following weight: 30 grams of the Radixs Astragali, 15 grams of Radix Zanthoxylis, 5 grams of Sanguis Draxonis, 15 grams of Boraxs, 1 gram, Cinnabaris, 2 grams, Radix Glycyrrhizae; Said medicine was ground to 100～120 mesh sieves and obtain fine powder, high temperature sterilize processing packs in bottle standby.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210148194.0A CN102698012B (en) | 2012-05-09 | 2012-05-09 | Externally applied traditional Chinese medicine for treating oral lichen planus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210148194.0A CN102698012B (en) | 2012-05-09 | 2012-05-09 | Externally applied traditional Chinese medicine for treating oral lichen planus |
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| Publication Number | Publication Date |
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| CN102698012A CN102698012A (en) | 2012-10-03 |
| CN102698012B true CN102698012B (en) | 2014-04-30 |
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| CN103736028A (en) * | 2014-01-11 | 2014-04-23 | 秦泽淼 | Traditional Chinese medicine composition for treating oral lichen planus |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073657A (en) * | 2006-04-20 | 2007-11-21 | 程岗 | 'Yu Chuang Dan' Chinese-medicinal preparation for treating recurrent oral exulceratio |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073657A (en) * | 2006-04-20 | 2007-11-21 | 程岗 | 'Yu Chuang Dan' Chinese-medicinal preparation for treating recurrent oral exulceratio |
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| CN102698012A (en) | 2012-10-03 |
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Owner name: RUDONG TECHNOLOGY CENTER Free format text: FORMER OWNER: LIU LIHUA Effective date: 20150618 |
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