CN104399053A - Drug for treating schizophrenia and preparation method - Google Patents
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- CN104399053A CN104399053A CN201410773014.7A CN201410773014A CN104399053A CN 104399053 A CN104399053 A CN 104399053A CN 201410773014 A CN201410773014 A CN 201410773014A CN 104399053 A CN104399053 A CN 104399053A
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Abstract
The invention discloses a drug for treating schizophrenia and a preparation method, and belongs to the field of traditional Chinese drugs. The drug comprises the following raw materials as active ingredients: pine needle, oxalis, liquorice, calamus, amber, Asarum caulescens Maxim, shelled cedar seeds, broad-leaved epiphyllum, thomnolia vermicularis, Gymnadenia conopsea, ganoderma, wormseed mustard, rhizoma zingiberis, flowerbelge, costustoot and calculus bovis. The drug is good in drug compatibility, and as the functions of promoting blood circulation, removing blood stasis, promoting the circulation of qi and relieving depression, promotes the active ingredients directly to the nidus by combining the active ingredients, is obvious in curative effect on schizophrenia, less in number of the active ingredients, low in toxic and side effects, free of obvious adverse reactions, easy to release the active ingredients of the drug, fast to absorb, easy to fully exert the drug effect, convenient to carry, easy to take, favorable for mass production, safe and effective.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to one and be used for the treatment of schizoid medicine and preparation method.
Background technology
Schizophrenia is the not bright major psychosis of one group of cause of disease, many person between twenty and fifty slow or subacute onset, often show as the different syndrome of symptom clinically, relate to the inharmonious of many-sided obstacles such as sensory perception, thinking, emotion and behavior and ergasia.The general Clear consciousness of patient, intelligence is normal, but some patients there will be the infringement of cognitive function in lysis.The course of disease is generally delayed, and in recurrent exerbation, increases the weight of or worsens, and decline and mental handicap finally appear in some patients, but some patients can keep recovery from illness or the state that is almost recovered after treatment.
Schizoid clinical symptoms complexity is various, and can relate to the aspects such as sensory perception, thinking, emotion, volitional behavior and cognitive function, between individuality, symptom is widely different, even if same patient also may show different symptoms in different phase or stadium.The most outstanding sensory perception obstacle is hallucination; Thought disturbance is schizoid core symptom, mainly comprises form of thinking obstacle and content of thought obstacle, and vain hope is the most common, most important content of thought obstacle; Apathy and emotional responses is inharmonious is the modal affective symptom of schizophrenic; The hypobulia of most of patients even lacks, and show as movable minimizing, peel off and stay alone, behavior is passive, lacks due enthusiasm and initiative, to clearly not intending in the future; In schizophrenic, the incidence rate of cognitive defect is high, and cognitive dysfunction appears in about 85% patient.
Due to the feature of disease itself, schizophrenia is a kind of chronic persistent disease of recurrent exerbation, and the state of an illness easily repeatedly.Recur the permanent damage all likely causing brain in patients each time, cognitive function further impaired, social function declines further; For family numbers of patients, recurrence means deterioration and the repeatedly enforceable hospitalization of relatives' state of an illness, must bear larger financial burden and causalgia; For medical personnel, recurrence can increase the difficulty for the treatment of, and final prognosis is undesirable.Therefore the schizoid recurrence for the treatment of in time has become one needs the urgent problem solved.
Antipsychotic medications is the remedy measures of schizophrenia first-selection.But current therapeutic modality prognosis is poor, is difficult to reach ideal effect, brings huge mental burden to patient and patient household.Chinese medicine is the same with food is derive from the mineral of the Nature, plant, animal drugs, and do not have toxic and side effects, Chinese medicine does not have Drug resistance, can continue to use until radical curing of disease.Therefore, we are badly in need of developing Chinese medicine that a kind of safety has no side effect and help patient and break away from the misery of sitting schizophrenia and bringing.
Summary of the invention
The invention provides one and be used for the treatment of schizoid medicine and preparation method; Compatibility of drugs of the present invention is suitable, and all medicines are harmonious and reach effect of blood circulation promoting and blood stasis dispelling, promoting QI circulation for relieving depression, the focus and effective ingredient goes directly; definite to Stability of Schizophrenia, flavour of a drug number is less, and toxic and side effects is little; there are no obvious adverse reaction; effective ingredient easily discharges, and absorb fast, drug effect is easily not fully exerted; be easy to carry; being easy to take, being beneficial to large-scale production, is a kind of safe and effective medicine.
For achieving the above object, technical scheme of the present invention is implemented as follows:
One is used for the treatment of schizoid medicine, and raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for schizoid medicine, comprise following processing step:
(1) by adding the water of 8 times amount after Folium Pini, Radix Glycyrrhizae, Herba Swertiae heteranthae, Flos Epiphylli Oxypetali, Thamnolia vermicularis (Ach.) Asa-hina, Herba Cassiopes selaginoidis, Coagulum Opuntiae sucus and Radix Aucklandiae mixing, extracting 2-3 hour, filtering, taking liquid; In remaining residue, add the water of 6 times amount again, extract 1-2 hour, filter, taking liquid; Merge twice medicinal liquid, for subsequent use;
(2) Herba Oxalidis Corniculatae, Semen Platycladi, Rhizoma Gymnadeniae, Herba Erysimi Cheiranthoidis and Calculus Equi are ground into powder, cross 200 order fine powders, for subsequent use;
(3) Rhizoma Acori Calami and succinum are picked decontamination, clean, slightly soak, run through, section, selenium is done, and grinds 180 order fine powders into powder, for subsequent use;
(4) by Rhizoma Zingiberis stripping and slicing, put in pot urgent stir-fry of useing force and heave to foaming, crust is coke yellow, and interior in yellow, spray clear water is a little, takes out, dries, grind into powder, crosses 120 order fine powders, for subsequent use;
(5) by medicinal liquid obtained for step (1), the obtained fine powder of step (2), step (3) and step (4) mixes, and makes tablet, is of the present inventionly to be used for the treatment of schizoid medicine.
The property of medicine of the present invention's Chinese medicine used is as follows:
Folium Pini: bitter in the mouth, warm in nature; GUIXIN, spleen channel.Dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching, blood-promoting and mind-easing.Main air wets flaccidity syndrome and arthralgia syndrome, beriberi, eczema, tinea, rubella pruritus, traumatic injury, neurasthenia, chronic nephritis, hypertension.Preventing encephalitis, influenza.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " control neurasthenia, Vitamin C lacks, trophedema; Prevent and treat epidemic encephalitis, influenza." modern medicine study confirmation, Folium Pini has sedation to central nervous system.
Herba Oxalidis Corniculatae: sour in the mouth, cold in nature; Return large intestine, small intestine meridian.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For cold, fever, enteritis, urinary tract infection, lithangiuria, neurasthenia; Traumatic injury is controlled in external, venom, carbuncle furuncle, tinea pedis, eczema, burn and scald." medical center bun will " carries: " tonifying the lung eliminating pathogen in the liver, except steam, blood stasis removing blood, yin fluid astringing." modern medicine study confirmation, Herba Oxalidis Corniculatae has antibacterial action to staphylococcus aureus.
Radix Glycyrrhizae: sweet in the mouth, property is put down.Enter spleen, stomach, lung meridian.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, clear throat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Rhizoma Acori Calami: bitter in the mouth, pungent, warm in nature.Reduce phlegm, have one's ideas straightened out, spleen invigorating, dampness removing.Control epilepsy, palpitate with fear forgetful, mind is not asked, and humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies." Chinese herbal medicine is commonly used in Shanghai " carries: " tranquillizing and allaying excitement, reduces phlegm, stomach invigorating.Control epilepsy, tinnitus, be thick of hearing, breast abdominal distention is vexed.”
Succinum: sweet in the mouth, property is put down; GUIXIN, liver, small intestine meridian, bladder, lung, spleen channel.Tranquillizing the mind by relieving convulsion, dissipating blood stasis stops blooding, relieving stranguria by diuresis, removing nebula improving eyesight.Main palpitation with fear insomnia, infantile convulsion epilepsy, stranguria with blood hematuria, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal, lump in the abdomen, order is raw hides from view, carbuncle sore tumefacting virus." Bencao Jingshu " carries: " succinum specially enters blood system.The main blood of the heart, blood stored in the liver, the popular feeling enters liver, therefore energy repercussive blood also.This medicine is wear down the property of oozing profit after all, unfavorable empty people.Mostly from pungent temperature medicine then promoting the circulation of blood removing blood stasis, ooze the medicine then capable water of sharp key from what is said or talked about, from metal and stone town pendant medicine then tranquilizing mind." modern medicine study confirmation, succinum has the effect of tranquillizing and allaying excitement, diuresis.
Herba Swertiae heteranthae: sweet in the mouth, micro-hardship, property is put down; GUIXIN, Liver Channel.Suppressing the hyperactive liver sun, tranquilizing by nourishing the heart, nourishing blood for regulating menstruation.Main dizziness, neurasthenia, hypertension, anemia, menoxenia.
Semen Platycladi: sweet in the mouth, property is put down; GUIXIN, kidney, large intestine channel.Tranquilizing by nourishing the heart, hidroschesis, intestine moistening.For fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation." detailed outline " carries: " Semen Platycladi, property is flat and cold not dry, sweet in the mouth and mending, and Xin Erneng moistens, its gas delicate fragrance, can heart kidney thoroughly, strengthening the spleen stomach, and the product medicine of covering also, the agent of nourishing should use it.”
Flos Epiphylli Oxypetali: sweet in the mouth, property is put down; Return lung, heart channel.Clearing away lung-heat to relieve cough, cooling blood for hemostasis, tranquilizing by nourishing the heart.Main cough due to lung-heat, pulmonary tuberculosis, spitting of blood, metrorrhagia, cardiopalmus, insomnia." Luchuan book on Chinese herbal medicine " carries: " lung heat clearing, cough-relieving are reduced phlegm.”
Thamnolia vermicularis (Ach.) Asa-hina: sweet in the mouth, hardship, light, cool in nature; Return lung, stomach, the heart, Liver Channel.Clearing away heat and promoting production of body fluid, refreshment and tranquilization.Main heatstroke, restlessness and thirst, cough due to lung-heat, deficiency of YIN hectic fever, epilepsy, insomnia, order disease." Shaanxi Chinese herbal medicine " carries: " heat clearing away is quenched one's thirst, and calms the nerves and nourishes heart, improving eyesight.Control dysphoria with smothery sensation in the heart, asthenia hectic fever due to YIN-deficiency, pneumonia is coughed, and epilepsy is manic, neurasthenia, and order is puckery, heatstroke, hypertension.”
Rhizoma Gymnadeniae: sweet in the mouth, warm in nature, profit.Tonify Qi of the kidney, spermatogenesis lung moistening.For pneumonopathy, cough and asthma due to lung deficiency, meat poison, seminal emission sexual impotence.
Herba Cassiopes selaginoidis: acrid in the mouth, micro-hardship, property is put down; GUIXIN, liver, stomach warp.Circulation of qi promoting, invigorates blood circulation, and pain relieving is calmed the nerves.Main stagnation of liver-QI and stomach-QI, Xie Lei institute abdominal distention and pain, rheumatic arthralgia, traumatic injury, insomnia." Xinhua's book on Chinese herbal medicine outline " carries: " property is put down for Herb: acrid in the mouth, micro-hardship.There are promoting the circulation of QI to relieve pain, mind-easing function.For stomachache due to hyperactive liver-QI attacking the stomach, inappetence, neurasthenia.”
Herba Erysimi Cheiranthoidis: bitter in the mouth, pungent, cold in nature; Attach to the lung and stomach meridians.Invigorating the spleen and regulating the stomach, diuresis heart tonifying.Main incoordination between the spleen and stomach, accumulation of food in the stomach and intes tine due to indigestion, and the edema of heart failure." Chinese herbal medicine is commonly used in Tibet " carries: " clearing away heat from blood, antitussive, heart tonifying.Be in harmony empty infections heating, pulmonary tuberculosis cough, prolonged illness cardianeuria, can separate meat poisoning." modern medicine study confirmation, erysimoside shows as the feature of cardiotonic glycoside from above at electrocardio.
Rhizoma Zingiberis: acrid in the mouth, hot in nature; Return spleen, stomach, the heart, lung meridian.Coldness and pain in the epigastrium, vomiting, have loose bowels, YANG-depletion is fainted inverse, and cold fluid-retention is breathed with cough, arthralgia due to cold-dampnes." property of medicine opinion " carries: " control ache in waist kidney cold, cold air, removing blood stasis, removes wind, and logical extremities joint, opens the vital organs of the human body, go the cold numbness of pathogenic wind toxic, night many urine.Control and cough, main warming middle-JIAO, cholera is more than, stomachache, and the full cold-dysentery of relieving distension, controls blood and close.Patient is empty and cold, should add and use it." modern medicine study confirmation, Rhizoma Zingiberis preserved material has suppression tendency to mice autonomic movement, can extend the length of one's sleep of cyclobarbital.
Coagulum Opuntiae sucus: sweet in the mouth, cold in nature.Clearing away heat and cooling blood, tranquilizing by nourishing the heart.Main hemorrhoidal bleeding, has blood in stool, and furuncle swells, and scalds, palpitation with a distress feeling, acute infantile convulsion wind." Traditional Chinese Medicine in Sichuan will " carries: " antipyretic calmness.Soothe sore throat, furuncle swells, and scalds, has blood in stool, proctoptosis, and the ear heart is burst pus and acute infantile convulsion wind.”
The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature; Return spleen, large intestine, tri-jiao channel.Promoting the circulation of QI to relieve pain, intestinal stasis relieving in tune.Main born of the same parents coerce distension foot, and abdominal distention, tells and have loose bowels, heavy after dysentery.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia, and middle gas is not economized, sudden deafness, snake bite and insect sting, toothache."Nei Jing" cloud: " heart master is smelly, the medicine that all gas is strong, all enters the heart, and the Radix Aucklandiae is fragrant and do not fall apart, then gas can be assigned, therefore can lead to its gas in small intestinal also again." modern medicine study confirms, the volatile oil of Radix Aucklandiae of low concentration and from volatile oil isolated various lactone part all can suppress the activity of Cavia porcellus and rabbit isolated heart to some extent, also have inhibitory action to isolated frog heart.
Calculus Equi: sweet in the mouth, salty, micro-hardship, cool in nature, mild toxicity; GUIXIN, Liver Channel.Relieving convulsionly to reduce phlegm, heat-clearing and toxic substances removing.Main infantile convulsion is demented, the hot coma of expectorant, hematemesis and epistaxis, phlegm-heat cough, malignant boil toxic swelling." modern Practical Chinese medicinal " carries: " effective for diseases such as nerve insomnia, hysteria, spasmodic coughs.And can detoxify, treatment of smallpox skin ulcer danger disease.”
The present invention compared with prior art, has following beneficial effect:
Compatibility of drugs of the present invention is suitable, and all medicines are harmonious and reach effect of blood circulation promoting and blood stasis dispelling, promoting QI circulation for relieving depression, the focus and effective ingredient goes directly; definite to Stability of Schizophrenia, flavour of a drug number is less, and toxic and side effects is little; there are no obvious adverse reaction; effective ingredient easily discharges, and absorb fast, drug effect is easily not fully exerted; be easy to carry; being easy to take, being beneficial to large-scale production, is a kind of safe and effective medicine.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) by adding the water of 8 times amount after Folium Pini, Radix Glycyrrhizae, Herba Swertiae heteranthae, Flos Epiphylli Oxypetali, Thamnolia vermicularis (Ach.) Asa-hina, Herba Cassiopes selaginoidis, Coagulum Opuntiae sucus and Radix Aucklandiae mixing, extracting 2-3 hour, filtering, taking liquid; In remaining residue, add the water of 6 times amount again, extract 1-2 hour, filter, taking liquid; Merge twice medicinal liquid, for subsequent use;
(2) Herba Oxalidis Corniculatae, Semen Platycladi, Rhizoma Gymnadeniae, Herba Erysimi Cheiranthoidis and Calculus Equi are ground into powder, cross 200 order fine powders, for subsequent use;
(3) Rhizoma Acori Calami and succinum are picked decontamination, clean, slightly soak, run through, section, selenium is done, and grinds 180 order fine powders into powder, for subsequent use;
(4) by Rhizoma Zingiberis stripping and slicing, put in pot urgent stir-fry of useing force and heave to foaming, crust is coke yellow, and interior in yellow, spray clear water is a little, takes out, dries, grind into powder, crosses 120 order fine powders, for subsequent use;
(5) by medicinal liquid obtained for step (1), the obtained fine powder of step (2), step (3) and step (4) mixes, and makes tablet, is of the present inventionly to be used for the treatment of schizoid medicine.
Usage and dosage: oral, every day 3 times, each 3 10 days is a course for the treatment of, and the lighter can fully recover 2 to 3 courses for the treatment of, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight number are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the schizoid medicine for the treatment of, select the routine clinical observation of schizophrenic 120 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 60 example, wherein male 30 example, women 30 example, age 18-58 year, 42 years old mean age, the course of disease 4 months-20 years; Matched group 60 example, wherein male 30 example, women 30 example, age 17-50 year, 38 years old mean age, the course of disease 5 months-10 years.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes medicine of the present invention, every day 3 times, each 3, and warm water delivery service in half an hour after meal 10 days is a course for the treatment of, and taking 2 to 3 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes risperidone, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: delusion of persecution, laugh without reason, with lively distinct phobic photis, parathymia, have no the transference cures such as emotional responses, the speech mechanically repeating people around or behavior, insensitive, mental disorder, disturbance in thinking, feed be abnormal, physical recovery is normal.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 46 examples, effective 10 examples, invalid 4 examples, cure rate is 76.7%, total effective rate 93.3%.
Cure 10 examples in matched group, effective 25 examples, invalid 25 examples, cure rate is 16.7%, total effective rate 58.3%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, field, man, 56 years old, retired cadre, people from Jixi of Heilongjiang.Patient suffers from schizophrenia more than 5 years, treats, do not take a favorable turn always at local hospital, after see a doctor again in Duo Jia hospital, do not cure yet.To our hospital afterwards, take 4 courses for the treatment of of medicine of the present invention, pick body; Continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, and follows up a case by regular visits to and does not recur, thoroughly cure.
2, in certain, female, 40 years old, enterprise personnel, people from Chengde.Mrs Wang is because the dead spirit of husband is subject to serious stimulation before 3 years, and one deck shade has been coverd with in from then on life, has suffered from paranoid schizophrenia.Introduce to our hospital by friend.After taking 2 courses for the treatment of of medicine of the present invention, pick body; Continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, and follows up a case by regular visits to and does not recur, thoroughly cure.
3, Wang, female, 32 years old, engineer, people from Binzhou, Shandong.Patient is admitted to hospital because suspecting to be poisoned half a year.Before sick, individual character is unsociable and eccentric, suspicious, reticent, responsive.Usually healthy, without severe disease history.Mother is mentally ill 20 years.To our hospital afterwards, check and be diagnosed as schizophrenia.After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better; After continuing to take 3 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
4, in certain, man, 26 years old, soldier.Patient is careless and lazy gradually because of life, does not keep discipline 1 year and is in hospital.Patient is timid since the childhood, reticent few speech, unsocial.Often look in the mirror, think that " nose uprises, and the fine change of eye is large for oneself." often laugh alone.Diagnosis is schizophrenia, after give medicine, but invalid.For asking further diagnosis and treatment, to our hospital.After taking 3 courses for the treatment of of medicine of the present invention, above-mentioned symptom alleviates; Continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom all disappears, and follows up a case by regular visits to and does not recur, and thoroughly cures.
5, certain is become, female, 24 years old, postgraduate, people from Guangan, Sichuan.Because learning anxiety, there is symptoms such as having a sleepless night, suspicious in patient, then to our hospital, is diagnosed as schizophrenia.After take 2 courses for the treatment of of medicine of the present invention after, above-mentioned symptom takes a turn for the better, and after continuing to take 1 course for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
6, Huang, female, 20 years old, student, people from Zhangjiajie, Hunan.There is insomnia without obvious cause, noted upper class hour not concentrating in patient, murmur to oneself, play the part of ugly face, do strange action, look in the mirror, giggle, head inserts flower sometimes before 5 months, be even barely sent to me and institute treat.Its female Zeng Yin " schizophrenia " is in hospital, and father suffers from " neurasthenia " and often goes to a doctor in psychiatric outpatient department.After take 2 courses for the treatment of of medicine of the present invention after, above-mentioned symptom takes a turn for the better; After continuing to take 4 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
Claims (5)
1. be used for the treatment of a schizoid medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Pini 38-58 part Herba Oxalidis Corniculatae 35-55 part Radix Glycyrrhizae 30-50 part Rhizoma Acori Calami 25-45 part
Succinum 24-44 part Herba Swertiae heteranthae 22-42 part Semen Platycladi 20-40 part Flos Epiphylli Oxypetali 15-35 part
Thamnolia vermicularis (Ach.) Asa-hina 14-34 part Rhizoma Gymnadeniae 12-32 part Herba Cassiopes selaginoidis 12-32 part Herba Erysimi Cheiranthoidis 10-30 part
Rhizoma Zingiberis 10-30 part Coagulum Opuntiae sucus 8-28 part Radix Aucklandiae 5-20 part Calculus Equi 4-16 part.
2. one according to claim 1 is used for the treatment of schizoid medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Pini 53 parts of Herba Oxalidis Corniculataes 50 portions of Radix Glycyrrhizaes 45 parts of Rhizoma Acori Calamis 40 parts
Succinum 39 parts of Herba Swertiae heteranthaes 37 parts of Semen Platycladi 35 parts of Flos Epiphylli Oxypetalis 30 parts
Thamnolia vermicularis (Ach.) Asa-hina 29 parts of Rhizoma Gymnadeniae 27 parts of Herba Cassiopes selaginoidis 27 parts of Herba Erysimi Cheiranthoidiss 25 parts
Rhizoma Zingiberis 25 parts of Coagulum Opuntiae sucus 23 parts of Radix Aucklandiae 16 parts of Calculus Equis 13 parts.
3. one according to claim 1 is used for the treatment of schizoid medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Pini 48 parts of Herba Oxalidis Corniculataes 45 portions of Radix Glycyrrhizaes 40 parts of Rhizoma Acori Calamis 35 parts
Succinum 34 parts of Herba Swertiae heteranthaes 32 parts of Semen Platycladi 30 parts of Flos Epiphylli Oxypetalis 25 parts
Thamnolia vermicularis (Ach.) Asa-hina 24 parts of Rhizoma Gymnadeniae 22 parts of Herba Cassiopes selaginoidis 22 parts of Herba Erysimi Cheiranthoidiss 20 parts
Rhizoma Zingiberis 20 parts of Coagulum Opuntiae sucus 18 parts of Radix Aucklandiae 12 parts of Calculus Equis 10 parts.
4. one according to claim 1 is used for the treatment of schizoid medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Pini 43 parts of Herba Oxalidis Corniculataes 40 portions of Radix Glycyrrhizaes 35 parts of Rhizoma Acori Calamis 30 parts
Succinum 29 parts of Herba Swertiae heteranthaes 27 parts of Semen Platycladi 25 parts of Flos Epiphylli Oxypetalis 20 parts
Thamnolia vermicularis (Ach.) Asa-hina 19 parts of Rhizoma Gymnadeniae 17 parts of Herba Cassiopes selaginoidis 17 parts of Herba Erysimi Cheiranthoidiss 15 parts
Rhizoma Zingiberis 15 parts of Coagulum Opuntiae sucus 13 parts of Radix Aucklandiae 8 parts of Calculus Equis 7 parts.
5. the preparation method being used for the treatment of schizoid medicine as described in claim 1-4, is characterized in that: comprise following processing step:
(1) by adding the water of 8 times amount after Folium Pini, Radix Glycyrrhizae, Herba Swertiae heteranthae, Flos Epiphylli Oxypetali, Thamnolia vermicularis (Ach.) Asa-hina, Herba Cassiopes selaginoidis, Coagulum Opuntiae sucus and Radix Aucklandiae mixing, extracting 2-3 hour, filtering, taking liquid; In remaining residue, add the water of 6 times amount again, extract 1-2 hour, filter, taking liquid; Merge twice medicinal liquid, for subsequent use;
(2) Herba Oxalidis Corniculatae, Semen Platycladi, Rhizoma Gymnadeniae, Herba Erysimi Cheiranthoidis and Calculus Equi are ground into powder, cross 200 order fine powders, for subsequent use;
(3) Rhizoma Acori Calami and succinum are picked decontamination, clean, slightly soak, run through, section, selenium is done, and grinds 180 order fine powders into powder, for subsequent use;
(4) by Rhizoma Zingiberis stripping and slicing, put in pot urgent stir-fry of useing force and heave to foaming, crust is coke yellow, and interior in yellow, spray clear water is a little, takes out, dries, grind into powder, crosses 120 order fine powders, for subsequent use;
(5) by medicinal liquid obtained for step (1), the obtained fine powder of step (2), step (3) and step (4) mixes, and makes tablet, is described to be used for the treatment of schizoid medicine.
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| US10383910B2 (en) | 2016-04-27 | 2019-08-20 | King Abdulaziz University | Methods of increasing fertility of a male subject with costus speciosus extract |
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