CN102680276A - Detection device - Google Patents
Detection device Download PDFInfo
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- CN102680276A CN102680276A CN2011100641933A CN201110064193A CN102680276A CN 102680276 A CN102680276 A CN 102680276A CN 2011100641933 A CN2011100641933 A CN 2011100641933A CN 201110064193 A CN201110064193 A CN 201110064193A CN 102680276 A CN102680276 A CN 102680276A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/08—Ergonomic or safety aspects of handling devices
- B01L2200/082—Handling hazardous material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/025—Displaying results or values with integrated means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0825—Test strips
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to a detection device. The detection device comprises a sample collecting cavity and a detecting cavity, wherein the sample collecting cavity comprises an opening capable of collecting fluid samples, a cavity bottom and a lateral wall capable of connecting the opening with the cavity bottom; the detecting cavity comprises at least one testing element; the testing element comprises a sample applying area and a testing area; the sample applying area is close to the opening of the collecting cavity; the position of the detecting cavity close to the opening of the sample collecting cavity also comprises a through hole; and the sample applying area is communicated with fluid of the sample collecting cavity through the through hole. The detection device can avoid a tester behaving affectedly through substituting the fluid samples; simultaneously, the detection device has the advantages of convenience for use, and safe and reliable performance.
Description
Technical field
The present invention relates to detect the device of sample, especially integrate the device of collecting and detecting sample.
Background technology
In the medical diagnosis field, it is more common detection that body fluid detects.Utilizing pick-up unit or detection cup to collect the tracer liquid sample, and judge whether contain analyte in the liquid sample, is a kind of commonplace method.Such pick-up unit or detection cup generally require sample cup to be collected in the sample container, and person skilled is inserted the detectable bar also is immersed in the sample part of reagent strip, take out reagent strip after the some time and read testing result.The detection of this mode, the technician may touch sample, and crisis is healthy or make sample contaminated.
At present, there are " step " method proving installation, for example United States Patent (USP) 7560272 described devices; During use; In case people to be tested is at the following fluid sample of hidden situation, for example urine is collected fluid sample in the collecting chamber of proving installation; Fluid sample carries out test assay, for example drugs examination with regard to contacting with the interior testing element of test chamber.This device but has its intrinsic defective, and for example, the testee is for certain purpose; Do not hope the own real result of going out to be tested, under hidden situation, the testee can be earlier nonself fluid samples such as water; Tap water for example; Join proving installation, carry out abandoning dummy copy after the dummy copy test, and then join the person that gives the professional test in the collecting chamber to the fluid sample of oneself.The test result that obtains like this is because testee " playing tricks " but not authentic and valid.
International patent application, publication number WO2010/12119 also discloses another kind of proving installation, and this device also can obtain test smoothly in order to solve under the sample situation seldom of collecting.But such device is under sample size situation normal or on the high side, and the rocking of device can let fluid sample splash or part is splashed and carries out improper test in advance on the testing element.
This can be avoided the testee to play tricks and make test result authentic and valid with regard to being necessary to provide a kind of, and proving installation is simple in structure simultaneously, low preparation cost, and operation steps simple " step " method proving installation also can be avoided testing in advance in addition.
Summary of the invention
In order to address the above problem, to the invention provides a kind of improved sample and receive pick-up unit.Use this pick-up unit can avoid the testee " to play tricks ", for example replace sample or carry out the dummy copy test earlier, replacing with own real sample then.
On the one hand, the present invention provides a kind of pick-up unit, and this device comprises collection well and the test chamber that is used to collect fluid sample, can comprise one or more testing elements in the test chamber.
In a mode, collection well comprises the opening that is used to collect fluid sample, at the bottom of the chamber, and the sidewall at the bottom of connection opening and the chamber; Testing element comprises that fluid sample applies zone and test zone, also comprises a through hole near the place of collecting chamber opening, and collecting chamber applies regional fluid through this through hole with the sample of testing element and is communicated with.Preferably, through hole is opened on the wall that constitutes test chamber.Preferably, proving installation also comprises a protective cover, and when collecting fluid sample, protective cover can be avoided fluid sample directly to contact with testing element through the through hole on the test chamber or apply regional the contact with the sample of testing element.Preferably, the sample of testing element apply the zone be positioned at through hole on the test chamber near.
In one embodiment, this proving installation also comprises a lid that covers opening, and after proving installation was squeezed, the fluid sample that is positioned at collecting chamber contacted with the testing element of test chamber through the through hole of test chamber.Preferably, through hole is between collecting chamber maximum collection fluid level and opening.
In another embodiment, test chamber is positioned at collecting chamber.In another mode, this device also comprises a cushion chamber, and test chamber is communicated with collecting chamber through cushion chamber.Preferably, cushion chamber also comprises a through hole, and the interior fluid of collecting chamber can get in the cushion chamber through the through hole in the cushion chamber, and the fluid that gets in the cushion chamber can contact through the entering test chamber of the through hole on the test chamber and with testing element.In another mode, the fluid in the collecting chamber gets in the cushion chamber through the through hole of cushion chamber earlier, and the through hole through test chamber gets in the test chamber then.In preferred mode, the parallel collecting chamber that is arranged in side by side of cushion chamber with test chamber, perhaps cushion chamber abuts against with test chamber and is arranged in collecting chamber.Optional, cushion chamber and/or test chamber can all be positioned at outside the collecting chamber.Preferred, the through hole on the test chamber is parallel substantially with test chamber with the formed passage of the through hole on the cushion chamber.In a preferred mode, through hole is positioned at testing element on through hole on the cushion chamber and the test chamber both sides or they are not located along the same line, and perhaps are positioned at the both sides of the plate that maintains testing element.In some modes, the partial sidewall of collecting chamber constitutes the partial sidewall of test chamber, and perhaps the partial sidewall of test chamber constitutes the partial sidewall of cushion chamber.In other modes; Test chamber is a rectangular parallelepiped; Cushion chamber abuts against with test chamber, and size shape is similar with test chamber, wherein the through hole on the test chamber be positioned at rectangular parallelepiped near long limit; Through hole on the cushion chamber is positioned near another long limit, and two each through holes are all near the opening near collecting chamber simultaneously.
Can comprise one or more testing elements in the test chamber, be used for detecting the multiple detection composition of sample.In some embodiments, testing element is a test strips.In some modes, testing element is set on the test board.
On the other hand, the present invention provides a kind of pick-up unit, and this device comprises the collecting chamber that is used to collect fluid sample, and collecting chamber comprises opening, at the bottom of the chamber and the sidewall at the bottom of connection opening and the chamber; Test chamber comprises at least one testing element in the test chamber, testing element comprises that sample applies zone and test zone; A lid that covers the collecting chamber opening; Wherein, device also comprises that one can let liquid in the collecting chamber get into the through hole that sample on the testing element applies the zone near near opening, wherein sample apply the zone be positioned at through hole near.Preferably, this through hole is positioned on the test chamber.
In a preferred mode, test chamber be positioned at collecting chamber and with collecting chamber common sparing sidewall.Preferably, proving installation also comprises a protective cover, and when collecting fluid sample, protective cover can be avoided fluid sample directly to contact with testing element through the through hole on the test chamber or apply regional the contact with the sample of testing element.
In another preferred mode, pick-up unit also comprises a cushion chamber, and cushion chamber comprises a through hole that is communicated with collecting chamber on the cushion chamber between test chamber and collecting chamber simultaneously.Preferred, in test chamber, comprise a test board, arranged at least one testing element on the test board, the through hole of cushion chamber is positioned at the downstream of test chamber through hole simultaneously.Preferably, the through hole of the through hole of cushion chamber and test chamber is positioned at the both sides of test board.Preferably, proving installation also comprises a protective cover, and when collecting fluid sample, protective cover can avoid fluid sample directly to get in the cushion chamber through the through hole on the cushion chamber.The purpose that increases a cushion chamber in the outside of test chamber is when having collected fluid sample behind collecting chamber; The mobile test device possibly cause that the fluid sample in the collecting chamber rocks and spatters and into cause antedating response in the test chamber; Even if because there is liquid to spill; Also at first got in the cushion chamber by the liquid that spilt, and the liquid that gets into cushion chamber is positioned at cushion chamber and can not get into test chamber, indirect like this test chamber is played a protective role.Preferably, test chamber and cushion chamber are arranged in collecting chamber.
On the other hand, the present invention provides a kind of method that detects sample, and this method comprises:
A pick-up unit is provided, and this device comprises appearance: the fluid sample collecting chamber, comprise the opening that is used to collect fluid sample, and at the bottom of the chamber, and the sidewall at the bottom of connection opening and the chamber; Test chamber comprises at least one testing element; This testing element comprises that sample applies zone and test zone; Wherein sample applies the zone near described collecting chamber opening; Wherein, test chamber also comprises a through hole in the place near the collection well opening, and sample applies this through hole of zone passage and is communicated with the collection well fluid;
Opening through collecting chamber is collected fluid sample;
Cover lid and to opening, seal collecting chamber;
The reversing pick-up unit is by standing upside down between collecting chamber and test;
Test result in the read test element test district.
Beneficial effect
The present invention is provided with and can prevents effectively that the testee from " playing tricks " and simple to operate, as long as " once the step " can be accomplished whole detection.
Description of drawings
Fig. 1 is the decomposing schematic representation of the device in the embodiment of the present invention;
Fig. 2 is the collecting chamber that assembles in Fig. 1 device and the structural drawing of seal; And with the synoptic diagram that separates of lid;
Fig. 3 A is Fig. 1 Device Testing chamber or cushion chamber structural representation; Fig. 3 B is the three-dimensional structure diagram of obturator;
Fig. 4 is the sectional view of Fig. 1 device;
Fig. 5 is the sectional view that device of the present invention is tested;
Fig. 6 is that device of the present invention carries out testing process process flow diagram figure, and wherein D representes that liquid level must change.
The explanation of accompanying drawing sign
Apparatus of the present invention 100, lid 10, seal 20; Testing element 40 applies zone 41, test zone 42, absorption region 43, test board 30, collecting chamber 54, collecting chamber opening 51; Sidewall 50, at the bottom of the chamber 52, test result reads window 53; At the bottom of the cushion chamber chamber 68, at the bottom of the test chamber chamber 78, cushion chamber sidewall 62, test chamber sidewall 63, test chamber sidewall 64, test chamber 70; Cushion chamber 60, seal 20, shield element 21, the part 25 of sealing cushion chamber, the part 24 in sealing detection chamber; Face of weld 85,86,88; Liquid level D; Handstand fulcrum A, B, C.
Describe in detail
Do some concrete embodiments of further explanation in the face of structure or these employed technical terms of liquid-sample collection device down, these explanations are not to further restriction of the present invention.
Sample
" sample " that the present invention refers to refer to needs chemical examinations whether exist with (or) analyze any material of analyte concentration; Maybe need confirm one or more samples whether exist with (or) material of the analyte of quantity, maybe need carry out the material of qualitative evaluation.Sample can be fluid sample, for example liquid sample.Liquid sample comprises body fluid, such as blood, serum, blood plasma, saliva, urine, tears, seminal fluid and marrow; Liquid sample also can be a water sample, such as seawater, river, river etc., perhaps from domestic water, municipal water use or service water resource, runoff water or sewage; Sample can be a food sample, such as milk and wine.Mucus, semisolid or solid sample can be used for making liquid, eluate, suspending liquid or leachate equal samples.For example, throat or genitals sample may be dipped in and process sample in the liquid.Sample can comprise potpourri or any relevant potpourri of liquid, solid and gas, such as the cell suspending liquid in dilution or the solution.Sample comprises biological substance, such as cell, microorganism, organelle and biochemical complexes.Liquid sample can be from producing such as solid, semisolid or high-viscosity materials such as soil, ight soil, tissue, organ, biological fluid or other occurring in nature non-liquid samples.For example, these solids or semi-solid samples can be mixed with one type of suitable solution of dilution.Sample can be macerated, freezing and thaw, perhaps other method for distilling form liquid samples.Remaining particulate material can use traditional method such as filtration or deposition to remove.In the specific embodiment, this sample is a urine, and this device is used for detecting the content of urine drugs.
Testing element
" testing element " is any element of carrying out test.In one embodiment, testing element is a test-strips.This test-strips can comprise that the material with specificity combination that is used for immunoassay above that is right.Test-strips can be a kind of test chemical bar that after detecting completion, passes through change color or other signals variation judged results.The sample that suitable the present invention detects includes but not limited to body fluid, separated sample from biological tissue or body fluid.For example, sample can be a saliva, blood, serum, blood plasma, urine, excreta, spinal fluid, vaginal secretion, mucus and tissue.Testing element is not limited to one, can be that two or more testing elements are arranged in pick-up unit simultaneously, respectively different component in the test sample book.Testing element can also be set on the test board.
Embodiment
In following detailed description, the explanation of accompanying drawing and corresponding character only is a mode of explaining that by way of example the present invention can actable specific concrete scheme.We do not get rid of the present invention can also be in any other embodiment in claim scope of the present invention.
Like Fig. 1-5 is embodiments more of the present invention.In the specific embodiment of the present invention, this device 100 comprises test chamber 70, collection well 54, and test chamber 70 is positioned at collection well 54.Collection well comprises the opening 51 of collecting fluid sample, at the bottom of the connection chamber 52 with the sidewall 50 of opening 51.On device, also comprise a through hole 80, for example through hole 80 is positioned on the wall of test chamber, let collecting chamber 54 interior fluid samples flow in the test chamber 70 through this through hole 80, and through hole 80 is near the opening 51 of collecting chamber.Here said " near opening " can be that through hole is positioned at below the opening, and the optional position that collecting chamber bottom is above can be at 1/2,2/3,3/4 place of collecting chamber height to the optional position between the opening; Through hole can be positioned on the sidewall 63 of test chamber.Certainly, the position of through hole 80 preferably is provided with maximum some positions of collecting on the fluid sample height at collecting chamber in advance, and after collecting fluid sample, fluid sample can just get in the test chamber before device is squeezed like this.In a preferred mode, comprise a testing element in the test chamber 70, the sample of testing element applies zone 41 through holes 80 near test chamber 70.Here the sample of said testing element apply the district 41 territories are settings of a relative position near through hole 80; Its refer to is squeezed or after whole detection device is squeezed when test chamber; Fluid sample in the test chamber directly or indirectly gets in the test chamber through the through hole 80 together with test chamber; Fluid sample elder generation contact sample applies zone 41 after getting into test chamber, and then contact detection zone 42.Preferably, last absorbing contacting regional 43.Testing element test chamber can with the test chamber opposing parallel, be arranged in test chamber vertically or other modes are arranged in test chamber.
In a preferred mode; Getting into test chamber for fear of the sample of when collecting sample, avoiding receiving causes the pollution of testing element or is splashed on the testing element and detect in advance; Can comprise a shield element 21 in the outside of through hole; Shield element 21 can be positioned on the test chamber, forms a protective cover like this.Shield element 21 can be taper, hat, ligulate.In addition, after being inverted pick-up unit, shield element can play the effect that compiles fluid sample.Certainly, joint detection chamber 70 can be one or more with the through hole 80 of collecting chamber 54, can Any shape with the shape in hole.Have reason to think that when the through hole 80 that is communicated with collecting chamber 54 and test chamber 70 when being a plurality of, each through hole can be provided with a barrier structure 21, perhaps several through holes are set under the barrier structure.In addition, testing element can be one, also can be a plurality of testing elements that are directed against different analytes respectively, and these testing elements can be placed on the test board 30, and test board is arranged in test chamber.Certainly, shield element 21 can be located immediately on the wall of test chamber.
In a preferred mode, the test result on the test chamber build-in test element can be observed so from the outside for transparent in the position of the corresponding testing element detection zone of the sidewall of collecting chamber.Preferred, the collecting chamber sidewall of corresponding testing element is planar structure rather than common circular shape, like this can be so that after test is accomplished, use the test result on the scanning machine sweep test element.Certainly, the whole sidewall that surrounds collecting chamber is a transparent material, for example is transparent plastic.
In addition, can also comprise a cushion chamber 60 in the outside near test chamber, cushion chamber 60 also comprises a through hole 90 that connects cushion chamber and test chamber 54 near test chamber 70 on cushion chamber, and the wall 62 that constitutes cushion chamber 60 is in the face of collecting chamber 54.Like this, test chamber 70 is crossed cushion chamber 60 with regard to turned and is connected with collecting chamber 54.Same, cushion chamber 60 can only be communicated with collecting chamber 54 fluids through through hole 90.Preferably; Through hole 90 preferably is positioned near near the opening 51, for example is positioned near the testing element sample to apply near the zone, and the position of the position of through hole 90 and through hole 80 has various selection equally; Certainly, it preferably also be positioned at maximum that collecting chamber is provided with collect fluid sample the top.Certainly, after the position height of through hole 90 set, being provided with respect to the position of the through hole 80 that is communicated with cushion chamber and test chamber can be much free.Outside test chamber 70, increase mainly acting as of a cushion chamber 60: if do not cushion cavity; After collecting chamber has been collected liquid; Owing to regular need be transported to chemical examination to the collecting chamber that fills fluid sample 54 short distances (for example from the lavatory to the laboratory); Fluid sample may be shaken in the transportation, so the fluid of fluctuation may directly get into the through hole 80 on the test chamber, thus the testing element in pollution detection chamber or the test chamber.For head it off, when a cushion chamber was set, the fluid of fluctuation then was introduced in the cushion chamber 60, because the Fluid Volume of fluctuation is smaller, so if the fluid of fluctuation is arranged, then they collect in 68 places at the bottom of the cushion chamber.Be positioned at place owing to connect the through hole 80 of cushion chamber and test chamber, just can not overflow and pollution detection chamber or testing element because of a spot of fluid near opening 51.
In addition, owing in operation, need be inverted whole detection device, sometimes be not the inversion of rule.Because proving installation integral body is cylindrical, inverse manner is random, and the optional position on the lid can be used as fulcrum and is inverted, and Fig. 6 is presented at a mode that causes when operating, and the C point is as inverted fulcrum in this mode.On the one hand; In carrying out inverted process; Fluid sample maybe be earlier through the through hole on the cushion chamber 90 enter into cushion chamber (when the through hole on the cushion chamber 90 be positioned at the below and as inverted fulcrum B the time), but the fluid that enters into cushion chamber can not get into the test chamber chamber.On the contrary, under the situation of collecting chamber shown in Figure 3, if leaning on into the place of through hole 80 to be inverted, because cushion chamber has liquid just to get into relatively safety as fulcrum A.
Preferably, on the through hole 90 of cushion chamber, also comprise shield element 21, certainly can understand, in such setting, just there is no need to be provided with again shield element 21 on the through hole 80 on the test chamber 70.Certainly, on the through hole 90 of cushion chamber, also shield element 21 can be set.Because the effect of cushion chamber also not too can impact the testing element in the test chamber in the absence of shield element.
In some preferred modes, for convenient making device of the present invention and the device of assembling this invention, the present invention also provides a method of producing this proving installation.This method comprises the steps: the collecting chamber shown in Fig. 3 B is provided, and in collecting chamber, isolates the test chamber 70 that test chamber 70 perhaps has cushion chamber 60.At the bottom of shared one of the end 68 of test chamber and the end of cushion chamber 78 and the collecting chamber (as shown in Figure 4).And in the place near opening 51, test chamber 70 be rectangular opening with cushion chamber 60, and test chamber and cushion chamber be by sidewall 64,63 simultaneously, 62 and the partial sidewall 50 of collecting chamber encircle a city.On the wall of cushion chamber, open a breach 91, on the public wall 63 of test chamber and cushion chamber, open a gap 80.These two breach are sealed the through hole 90 on the through hole 80 that forms respectively after lid 20 sealing on the test chamber and the cushion chamber; In Fig. 3 B, they are positioned at the both sides of test board or are positioned at the opposition both sides of cushion chamber.Be inserted into the test board that has testing element 40 30 that assembles in the test chamber then, letting the sample of testing element apply the zone and be positioned near near the breach 81.The partial devices that Fig. 3 B is shown can once injection moulding or is repeatedly carried out the seal group dress after the moulding.A seal 20 is provided in addition, and his shape and test chamber or similar with the test chamber that has cushion chamber can be sealed in the local of test chamber upper shed or while sealing detection chamber and cushion chamber.Seal 30 also can be plastic material; Form sealing detection chamber and cushion chamber opening through welding; Two independently cavitys have just been formed: two through holes 80 and 90 connections (Fig. 2,4) of test chamber 70 and 60, two chambeies of cushion chamber through forming in breach 801 and 91 regional centers.Concretely, like Fig. 3 A, seal comprises the opening of two plane domains 24 and 25 corresponding cushion chambers of difference and test chamber, and two plane domains and sidewall 62,63,64 contacts also are welded to connect face of weld 85,86,88 sealing detection chamber and cushion chambers.Certainly better in the mode, seal can comprise a shield element 21 corresponding with through hole 91, and seal and shield element 21 can disposal moldings.
Such device in use at first receives fluid sample with collecting chamber, and the height of the fluid sample of preferably collecting does not surpass the place of the through hole 90 on the cushion chamber 60.Certainly; If do not note overcharging a little and collected fluid sample; Urine for example, unnecessary fluid sample also can flow in the cushion chamber 60 through through hole 90, again because the through hole 80 on the test chamber is positioned at the place near opening 51; Just away from 52 place at the bottom of the chamber, the liquid that gets into 60 li of cushion chambers can not get in the test chamber 70 yet.After collecting well; The transmission or deliver to the laboratory and chemically examine; The assayer covers (Fig. 4,2) on the opening 51 to lid 10, is inverted pick-up unit then; This time fluid sample through being communicated with cushion chamber 60 and collecting chamber 54 through hole 90 and be communicated with cushion chamber 60 and the through hole 80 of test chamber 70 and get into and apply zone 41 with the sample of testing element in the test chamber 70 and contact, get into and apply regional sample and pass through surveyed area 42 and sample absorption region 43 (if any) successively; The final completion tested, and whole flow process is as shown in Figure 6.
Claims (15)
1. pick-up unit comprises:
Collection well comprises the opening that is used to collect fluid sample, at the bottom of the chamber, and the sidewall at the bottom of connection opening and the chamber;
Test chamber comprises at least one testing element; This testing element comprises that sample applies zone and test zone; Wherein sample applies the zone near described collecting chamber opening;
Wherein, test chamber also comprises a through hole in the place near the collection well opening, and sample applies this through hole of zone passage and is communicated with the collection well fluid.
2. device as claimed in claim 1, after this pick-up unit was squeezed, the fluid in the collecting chamber flow in the test chamber through this through hole and applies regional the contact with the sample of testing element.
3. pick-up unit as claimed in claim 1 is characterized in that said test chamber is positioned at collection well.
4. sample testing apparatus as claimed in claim 1, described testing element is set on the test board, and test board is arranged in test chamber.
5. sample testing apparatus as claimed in claim 1, the through hole on the described test chamber also comprises a barrier structure.
6. like claim 1 or 3 described sample testing apparatus, it is characterized in that this device also comprises cushion chamber, collecting chamber is communicated with test chamber through cushion chamber.
7. pick-up unit as claimed in claim 6 is characterized in that cushion chamber is positioned at collecting chamber, and is positioned at the homonymy of collecting chamber with test chamber.
8. pick-up unit as claimed in claim 7 is characterized in that cushion chamber comprises a through hole in the place near the collecting chamber opening, and the through hole on the cushion chamber is communicated with vented liquid on the test chamber.
9. pick-up unit as claimed in claim 8; It is characterized in that; Outside the through hole of cushion chamber, comprise a protective cover, this protective cover can avoid collecting chamber when receiving fluid sample fluid sample through cushion chamber the through hole sample that gets into test chamber and engaged test element apply the zone.
10. pick-up unit as claimed in claim 6, wherein, the interior fluid sample of collecting chamber gets into cushion chamber through the through hole of cushion chamber earlier, and then through contacting with testing element in the entering of the through hole on the test chamber test chamber.
11. a pick-up unit, this device comprises:
Be used to collect the collecting chamber of fluid sample, collecting chamber comprises opening, at the bottom of the chamber, and the sidewall at the bottom of connection opening and the chamber;
Test chamber comprises at least one testing element in the test chamber, testing element comprises that sample applies zone and test zone;
Cover the lid of collecting chamber opening;
Wherein, device also comprises that a sample that can let liquid in the collecting chamber get into testing element applies the through hole in zone near near opening, wherein sample apply the zone be positioned at through hole near.
12. pick-up unit according to claim 11; Wherein proving installation also comprises a protective cover; When collecting fluid sample, protective cover can be avoided fluid sample directly to contact with testing element through the through hole on the test chamber or apply regional the contact with the sample of testing element.
13. pick-up unit according to claim 11, wherein pick-up unit also comprises a cushion chamber, and cushion chamber comprises a through hole that is communicated with collecting chamber on the cushion chamber between test chamber and collecting chamber simultaneously.
14. pick-up unit according to claim 13, wherein testing element is positioned on the test board, and the through hole of cushion chamber and the through hole of test chamber are positioned at the both sides of test board.
15. a method that detects sample, this method comprises:
A pick-up unit is provided, and this device comprises appearance: the fluid sample collecting chamber, comprise the opening that is used to collect fluid sample, and at the bottom of the chamber, and the sidewall at the bottom of connection opening and the chamber; Test chamber comprises at least one testing element; This testing element comprises that sample applies zone and test zone; Wherein sample applies the zone near described collecting chamber opening; Wherein, test chamber also comprises a through hole in the place near the collection well opening, and sample applies this through hole of zone passage and is communicated with the collection well fluid;
Opening through collecting chamber is collected fluid sample;
Cover lid and to opening, seal collecting chamber;
The reversing pick-up unit is by standing upside down between collecting chamber and test;
Test result in the read test element test district.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
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| CN2011100641933A CN102680276A (en) | 2011-03-15 | 2011-03-15 | Detection device |
| PCT/CN2012/071858 WO2012122899A1 (en) | 2011-03-15 | 2012-03-02 | Detection device |
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| CN2011100641933A CN102680276A (en) | 2011-03-15 | 2011-03-15 | Detection device |
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| CN102680276A true CN102680276A (en) | 2012-09-19 |
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| CN2011100641933A Pending CN102680276A (en) | 2011-03-15 | 2011-03-15 | Detection device |
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| CN (1) | CN102680276A (en) |
| WO (1) | WO2012122899A1 (en) |
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| WO2014177927A3 (en) * | 2013-04-30 | 2015-03-05 | Microtri Limited | Bodily fluid specimen collection and assay device |
| CN105842434A (en) * | 2016-03-16 | 2016-08-10 | 杭州安旭科技有限公司 | Sample collection and detection apparatus |
| WO2017201723A1 (en) * | 2016-05-27 | 2017-11-30 | 卓金星 | Microorganism detection system |
| CN107782883A (en) * | 2016-08-26 | 2018-03-09 | 艾博生物医药(杭州)有限公司 | A kind of collection and detection device of fluid sample |
| WO2020128480A3 (en) * | 2018-12-21 | 2020-07-30 | Waterscope Limited | Cartridge |
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| WO2014177927A3 (en) * | 2013-04-30 | 2015-03-05 | Microtri Limited | Bodily fluid specimen collection and assay device |
| CN105842434A (en) * | 2016-03-16 | 2016-08-10 | 杭州安旭科技有限公司 | Sample collection and detection apparatus |
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| CN113242768A (en) * | 2018-12-21 | 2021-08-10 | 水景有限公司 | Box |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012122899A1 (en) | 2012-09-20 |
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Application publication date: 20120919 |