CN102379724B - Device for collecting fluid samples - Google Patents

Device for collecting fluid samples Download PDF

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Publication number
CN102379724B
CN102379724B CN201010276019.0A CN201010276019A CN102379724B CN 102379724 B CN102379724 B CN 102379724B CN 201010276019 A CN201010276019 A CN 201010276019A CN 102379724 B CN102379724 B CN 102379724B
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China
Prior art keywords
collecting chamber
applicator
cavity
chamber
absorption piece
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CN201010276019.0A
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CN102379724A (en
Inventor
胡海鹏
杨华强
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ABON Biopharm Hangzhou Co Ltd
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ABON Biopharm Hangzhou Co Ltd
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Abstract

The invention provides a device for collecting fluid samples. The device comprises a sample collector, a sealing element and a collecting cavity, wherein the sample collector comprises a compressible absorbing part for collecting the samples; the sealing element is used for sealing the collecting cavity; the collecting cavity is used for receiving the sample collector; the sample collector is provided with a high position and a low position in the collecting cavity; when the sample collector is located at the high position, the sealing element and the side wall in the collecting cavity are in contact to form sealing; and the sealing element forms a cavity in the collecting cavity, and the absorbing part is arranged in the cavity. The invention also provides a device for detecting the fluid samples, comprising the device for collecting the samples and a detecting element; and the detecting device can be also provided with a fluid storage cavity so as to integrate collection, detection and fluid storage into a whole. The devices provided by the invention can be used for collecting enough fluid samples so as to complete collection, detection and sample storage smoothly.

Description

A kind of device for collecting fluid sample
Technical field
The present invention relates to fluid specimen collection device, and checkout gear, especially there is gathering-device and the checkout gear of the cavity of collected fluid sample.
Background technology
Background technology below for helping reader understanding the present invention, and can not be considered to prior art.
In our society, illicit drug use has become one and has generally acknowledged and the social problem increasingly worsened.2003, U.S. Department of Health and Human Service investigation found about have 1,950 ten thousand Americans or the crowd of 8.2% age more than 12 years old to suck illicit drugs." use illicit drugs recently " and refer to carry out investigating in the previous moon at U.S. Department of Health and Human Service and use a kind of illicit drugs.Fructus Cannabis is found to be the most frequently used illicit drugs, accounts for 6.2% (1,460 ten thousand).Estimate that 2,300,000 people (1.0%) use cocaine, 604 now, 000 people employs KUAIKE, and have 1,000,000 people to use hallucinogen, and estimate 119,000 people uses heroin.
In order to hit drug dependence and this social problem of monitoring, drug test is for example employed in every profession and trade, educate, physical culture, law enforcement etc. become standard test procedure.In order to promote this effort, drug test industry is formed.This industry provides various drug test product.The A urine sample collection device cup can analyzed sample is the test products of a classics.These devices may be complicated, difficulties or dirty concerning user, or for concealing the situation using illicit drugs recently, may cause the problem that sample is adulterated.In addition, urine sample cannot be collected in some occasion, such as in roadside or public arena.
Therefore better method and apparatus is needed to collect sample and detect.US Patent No. 2004/0184954 and US2004/0237674 disclose other and collect the device that salivas carrying out detect.In these two patents, both provide the apparatus and method of collecting and detecting saliva, in these devices, when sample is sampled after on catcher, by applying external force, the sample in absorption piece on catcher is expressed in collecting chamber, and then detects.But sample can not all be extruded in collecting chamber, especially saliva sample, and foam is many, and viscosity is high, and collecting amount reduces especially greatly; Thus affect the detection of this fluid sample, or be used for confirming without unnecessary sample after pattern detection.
Summary of the invention
In order to address this problem, the invention provides a kind of device of collection fluid sample newly, this device is by applicator, and potted component and collecting chamber form.Applicator comprises the compressible absorption piece for collecting fluid sample; Collecting chamber is for receiving applicator and fluid sample, and this collecting chamber is made up of sidewall and bottom; Applicator has a high position and low level in collecting chamber; When applicator is arranged in collecting chamber high-order, the sidewall contact in potted component and collecting chamber also forms sealing; Sealing element forms a cavity in collecting chamber, and absorption piece is positioned at this cavity.
When the absorption piece with fluid sample is put in collecting chamber, when namely catcher is positioned at a high position, potted component contacts with collecting chamber medial wall and is formed and seals, now, form a cavity by bottom potted component and collecting chamber medial wall and collecting chamber, absorption piece is positioned at this cavity, simultaneously, the fluid sample that absorption piece adsorbs also is positioned at this cavity, and now, absorption piece is not compressed.Seal because potted component and collecting chamber medial wall are formed, therefore, when using external force that the fluid sample on absorption piece is flow in collecting chamber, fluid sample can not flow out along collecting chamber medial wall or be exuded to outside cavity, ensures to collect enough sample sizes.
When applicator is arranged in the low level of collecting chamber, potted component still contacts with the sidewall in collecting chamber and is formed and seals; The cavity that potted component and collecting chamber are formed and absorption piece are compressed, and the fluid sample on absorption piece is received in collecting chamber.
When catcher moves to low level by a high position in collecting chamber, this cavity is compressed, and space reduces, and the air therefore in cavity and absorption piece are also compressed, and in absorption piece, fluid sample is squeezed out and flows out in collecting chamber because of the compression of absorption piece.In whole compression process, potted component moves along collecting chamber medial wall along with diminishing of cavity, and keeps the sealing with medial wall always.Therefore, in compression process, do not have fluid sample yet and be leaked to outside by potted component and collecting chamber medial wall sealing place, ensure that the abundant collection of fluid sample, thus solve the problem of fluid specimen collection deficiency.
In some embodiments, when applicator be arranged in collecting chamber high-order time, potted component is with the sidewall contact in collecting chamber and seal, bottom this collecting chamber and the cavity that forms of sidewall and potted component be a cavity sealed.Like this, be positioned at inner absorption piece after being compressed, namely after applicator moves to low level from a high position, absorption piece is compressed very thorough, and thus fluid sample is as much as possible is extruded.
In some embodiments, potted component can be positioned in applicator, along with applicator is moved together in collecting chamber.When applicator is positioned at a collection control high position and low level, the potted component be positioned in applicator contacts with collecting chamber medial wall and seals collecting chamber.
In a detailed description of the invention, a piston is positioned in applicator, and piston has a high position and low level; When piston is positioned at a high position, applicator is positioned at a high position for collecting chamber; When piston is positioned at low level, applicator is positioned at the low level of collecting chamber.In one more specifically embodiment, piston is positioned at above absorption piece, and potted component is positioned in piston circumferential exterior surface, and when piston is positioned at collecting chamber with collection well, the potted component on piston and collecting chamber medial wall are formed and seal.
Potted component used in the present invention is the parts that can play sealing function, can for having elastic sealed material.In an embodiment, potted component is O shape ring.
In order to ensure better sealing effectiveness, in some embodiments, collecting chamber medial wall can be designed with the gradient, and its gradient increases along a collecting chamber high position gradually to low level; Namely the cross section of this medial wall is trapezoidal wherein, trapezoidal top is that collecting chamber is high-order, and trapezoidal is collecting chamber low level below, and trapezoidal top is greater than trapezoidal following.Along with the increase of the gradient, potted component and collecting chamber medial wall seal tighter, thus sealing property is better.
In some embodiments, applicator can be locked during low level and remain in collecting chamber in collecting chamber.In a concrete embodiment, applicator comprises circumference and screws in screw thread, and collecting chamber comprises circumference and receives screw thread; When sample divider is in low level, screws in screw thread and receive engagement threads.
In further embodiments, applicator can also include a lid, lid there is circumference screw in screw thread, to accept screw thread supporting with the circumference on collecting chamber, when applicator is positioned at low level, on the screw thread of lid and collecting chamber, circumference accepts engagement threads, and applicator and collecting chamber are bonded together.
Absorption piece in the present invention can be suitable for being placed on the sponge in person under inspection's mouth; And fluid sample can be saliva.In one embodiment, mouth applicator being put into tester carries out sample collection, makes catcher be full of saliva.
The present invention also provides a kind of Sample fluid testing devices, comprises fluid collection device and testing element.Specifically comprise applicator, this applicator comprises the compressible absorption piece for collecting fluid sample; Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom; Potted component, for sealing collecting chamber; Testing element, is positioned in applicator or collecting chamber; Same, applicator has a high position and low level in collecting chamber; When applicator is arranged in collecting chamber high-order, potted component contacts with collecting chamber medial wall and is formed and seals; Potted component and collecting chamber form a cavity, and absorption piece is positioned at cavity.When applicator is arranged in the low level of collecting chamber, potted component still contacts with collecting chamber medial wall and is formed and seals; The cavity that potted component and collecting chamber are formed and absorption piece are compressed, and the fluid sample on absorption piece is received in collecting chamber.
In certain embodiments, testing element is positioned at collecting chamber, is connected with fluid sample by path.In further embodiments, testing element is positioned in applicator, and testing element is communicated with absorption piece fluid by connecting absorption piece and the passage in the applicator of testing element.
On the other hand, the present invention also provides the sample testing apparatus with liquid storage function, comprising: applicator, and this applicator comprises the compressible absorption piece for collecting fluid sample; Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom, and this collecting chamber also comprises test chamber outlet and reservoir outlet; Test chamber; A testing element is at least comprised in test chamber; Plug Division, cooperatively interacts with collecting chamber; Reservoir compartment; For storing the fluid sample of collection; Potted component, for sealing collecting chamber; Reservoir compartment is connected with collection well by outlet corresponding on collecting chamber with test chamber.Applicator has a high position and low level in collecting chamber; When applicator is arranged in collecting chamber high-order, potted component contacts with collecting chamber medial wall and is formed and seals; Potted component and collecting chamber form a cavity, and absorption piece is positioned at cavity.When applicator is arranged in the low level of collecting chamber, potted component still contacts with collecting chamber medial wall and is formed and seals; The cavity that potted component and collecting chamber are formed and absorption piece are compressed, and the fluid sample on absorption piece is received in collecting chamber.
In some embodiments, the cavity that potted component and collecting chamber are formed can be sealing.
In other modes, potted component can be positioned in applicator.In more excellent embodiment, a piston is also positioned in applicator, and is positioned at the top of absorption piece, and potted component is then in the circumferential exterior surface of piston.Piston, absorption piece is along with catcher has high-order to lower position in collecting chamber together with potted component, and when moving, potted component keeps sealing with collecting chamber medial wall always.
Equally, in some embodiments, collecting chamber medial wall also can be designed with the gradient, and its gradient increases along a collecting chamber high position gradually to low level.Namely the cross section of this medial wall is trapezoidal wherein, trapezoidal top is that collecting chamber is high-order, and trapezoidal is collecting chamber low level below.Along with the increase of the gradient, potted component and collecting chamber medial wall seal tighter, thus sealing property is better.
In certain embodiments, collection well and connector supporting with it can rotate, and when turning to primary importance, collecting chamber is connected with reservoir compartment, and now test chamber is not communicated with collecting chamber; When turning to the second position, collecting chamber is connected with test chamber, and reservoir compartment is communicated with collecting chamber.
Applicator and collection well can have supporting screw-in or screw out screw thread, and in order to fool proof, the screw-in direction of this matching thread is contrary with the direction that collecting chamber primary importance turns to the second position.
In order to more effective collection fluid sample, collection well can arrange upper and lower two cavitys, and centre plate washer separates, and absorption piece is positioned at the cavity that potted component and upper cavity are formed.Upper and lower cavity is provided with aperture and is connected.When absorption piece is compressed in upper cavity, fluid sample is extruded and flow to lower chamber by aperture, and the effective fluid sample that stops is back in absorption piece, ensure that and collects sample more fully.Lower chamber is provided with reservoir outlet and test chamber outlet.When collecting chamber turns to primary importance, collecting chamber lower chamber reservoir outlet is communicated with reservoir compartment, and collecting chamber inner fluid sample flow in reservoir compartment by this outlet; When collecting chamber turns to the second position, the outlet of collecting chamber lower chamber test chamber is communicated with test chamber, and collecting chamber sample after tested chamber outlet flow into test chamber, contacts, complete detection with testing element.
Conveniently take out the storage sample of reservoir compartment, on base, above reservoir compartment, corresponding position can arrange sample tap.In order to obtain abundant storage sample, can arrange a groove bottom the reservoir compartment that sample tap is corresponding, the sample in reservoir compartment more concentrates on groove, convenient sampling.
Beneficial effect
Gathering-device provided by the invention, because of the space of the Packed collection liquid sample of tool, increases compressing force and can effectively stop sample to leak, thus can collect abundant liquid sample.
Accompanying drawing explanation
Fig. 1 is the schematic perspective view of the present invention's device
Fig. 2 is the STRUCTURE DECOMPOSITION figure of Fig. 1 device
Fig. 3 to Fig. 6 is operation chart and the Operation Profile schematic diagram of device of the present invention
Fig. 3 a, Fig. 3 b are the schematic diagram before applicator puts into collecting chamber
Fig. 4 a, Fig. 4 b are the schematic diagram that applicator puts into collecting chamber (namely high-order)
Fig. 5 a, Fig. 5 b are the low level schematic diagram of applicator, and collecting chamber is positioned at primary importance schematic diagram simultaneously
Fig. 6 a, Fig. 6 b are that collection well is positioned at second position schematic diagram
Fig. 7 is the schematic diagram that testing element is positioned in applicator
Description of reference numerals
Applicator 110; Lid or be affectedly bashful portion 101; Pillar 102; Piston 103; Potted component 104; Absorption piece 105; Collecting chamber 120; With the Plug Division 130 that collecting chamber is supporting, comprise the base 140 of test chamber and liquid storage cylinder; Liquid storage cylinder 401; Test chamber 402; Testing element 403, sample tap 405, liquid storage cylinder groove 411, the high position 601 of catcher in collecting chamber; The low level 602 of catcher in collecting chamber; Collecting chamber medial wall 201; Collecting chamber primary importance 406, the collecting chamber second position 407; Reservoir outlet 412; Test chamber outlet 413; Collecting chamber upper cavity 202; Collecting chamber lower chamber 203
Below the technical term that structure or these of liquid-sample collection device use is described further.
sample
The sample of indication of the present invention refers to that those can be used for detecting, chemically examining or diagnose the material that whether there is interested analyte.Sample can be fluid sample, and such as, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise the liquid solution that solid sample and semi-solid samples are formed after anticipating.The sample that collection comes may be used for the methods such as immune detection, chemical detection, enzyme detection and detects whether there is analyte.
testing element
" testing element " is any element performing test.In one embodiment, testing element is test strip.This test strip can comprise thereon for the material pair with specific binding of immunoassay.Test strip can be a kind of change by color upon completion of the assays or the test chemical bar of other signal intensity judged results.Be suitable for the sample that the present invention carries out detecting and include but not limited to body fluid, the sample be separated from biological tissue or body fluid.Such as, sample can be saliva, blood, serum, blood plasma, urine, Excreta, spinal fluid, vaginal secretion, mucus and tissue.Testing element is not limited to one, can be that two or more testing element is arranged in checkout gear simultaneously, respectively different component in test sample book.
applicator
The present invention also provides applicator 110.In one embodiment, applicator 110 has an absorber element 105 and is affectedly bashful portion 101.Other sponge of medical grade that absorber element 105 is commonly used by this area usually or plastic foam material are made.But many other materials also can be made into absorber element, such as Cotton Gossypii or paper, or other any materials with water absorbing properties.Applicator can soaked containing stimulating in the salivary solution of tester in advance.Thus make more easily to collect saliva when catcher puts into tester's mouth.Be affectedly bashful portion's normally rigidity, be conducive to the operation to absorber element.The material that the portion of being affectedly bashful can be commonly used by this area is made, such as plastics, timber, metal or cardboard.In an embodiment, the portion top of being affectedly bashful can be a lid form, forms matching thread with collecting chamber.In another embodiment, testing element connects on the collector, and absorption piece and testing element are connected there being path.
Detailed description of the invention
In the following detailed description, accompanying drawing and corresponding explanatory note are only illustrate that the present invention can the mode of actable specific concrete scheme by way of example.We do not get rid of the present invention can also without prejudice to any other detailed description of the invention within the scope of the claims in the present invention.
Gathering-device advantage provided by the present invention fully collects liquid sample, and particularly viscosity is high, the saliva equal samples that foam is many.As depicted in figs. 1 and 2, this gathering-device basic structure is by applicator 110, and collection well 120 and potted component 104 are formed.Applicator 110 comprises absorption piece 105, is affectedly bashful portion 101 and the pillar 102 both connection, is affectedly bashful portion 101 and also can be designed to the lid supporting with collecting chamber 120.Potted component 104 can be placed in collecting chamber 120, such as invests the "O"-ring on collecting chamber 120 medial wall; Also can be connected in applicator 110, when potted component 104 is positioned in applicator 110, need to be placed on absorption piece 105 and to be affectedly bashful between portion or lid 101.In a specific embodiment, potted component 104 is attached on the pillar 102 of catcher 110, is connected together with absorption piece 105.
In a concrete embodiment, the absorption piece 105 of applicator 110 is put into tester's mouth and collects sample.As Fig. 3 a schematic diagram and Fig. 3 b generalized section, catcher 110 after sampling is put into collection well 120, now, absorption piece 105 and collecting chamber 120 bottom connection touch, and namely catcher 110 is positioned at a high position 601 for collecting chamber 120, as shown in fig. 4 a, specifically see shown in Fig. 4 b profile, now, potted component 104 contacts with collecting chamber medial wall 201 and is formed and seals, and forming a cavity, absorption piece 105 is not compressed in cavity.When catcher 110 is further bottom collecting chamber 120 internal motion to collecting chamber, namely during low level 602, as shown in Fig. 5 b profile, now, potted component 104 also moves to low level 602 by high-order 601 together along with catcher 110, and keeps contacting with collecting chamber medial wall 201 and sealing always.The cavity that potted component 104 and collecting chamber 120 are formed reduces along with the motion of catcher 110, and the absorption piece 105 being positioned at this intracavity is compressed, thus the fluid sample investing absorption piece 105 just enters in collection well 120.
In another detailed description of the invention, when applicator 110 in collecting chamber high-order 601 time, the cavity that potted component 104 and collecting chamber 120 are formed can be sealing.Like this when compressing this cavity, because of space sealing, intrinsic pressure increase, it is more thorough that absorption piece is extruded, and fluid sample then more to be extruded.
In other embodiments, in order to accelerate compression chamber or seal chamber, a piston 103 is positioned in applicator 110, as shown in Figure 2, move in collecting chamber 120 together with applicator 110, piston 103 is synchronous with applicator 110, and when piston 103 is positioned at a high position, applicator 110 is also arranged in a high position for collecting chamber 120; Equally, when piston 103 moves to low level, applicator 110 is also positioned at low level.In another more specifically embodiment, piston 103 is positioned on catcher pillar 102, adjacent with absorption piece 105 and be positioned at above absorption piece 105, and meanwhile, potted component 104 is positioned on piston 103; Such as potted component 104 is positioned in piston 103 circumferential exterior surface, as shown in Figure 2.When catcher 110 is arranged in collecting chamber 120, the potted component 104 be positioned on piston is formed with collecting chamber medial wall 201 and seals, and when catcher moves to low level 602 by high-order 601, potted component 104 contacts with collecting chamber medial wall 201 and formed always and seals.
In other embodiments, in order to ensure better sealing effectiveness, sample collection chamber inner sidewall 201 is designed with the gradient, and the gradient increases gradually along in outer course, namely increases gradually along the high position 601 of applicator 110 in collecting chamber to low level 602.Namely this collecting chamber cross section is ladder diagram, and the high-order trapezoidal side of this collecting chamber is greater than the trapezoidal side at collecting chamber low level place.Like this, have elastic potted component 104 when moving with collecting chamber medial wall 201, big-endian, the gradient increases gradually, and elastic potted component 104 is compressed more, seal tightr, thus sealing property is better with medial wall 102.
The present invention is providing on the basis of collecting fluid sample, also provides and detects the device that these collect sample, comprise applicator 110, potted component 104, collecting chamber 120 and testing element 403.Wherein, testing element 403 can be connected in applicator 110 and to be communicated with absorption piece 105 fluid-phase, as shown in Figure 7; Also directly can be placed in collecting chamber 120 or with collecting chamber 120 and be communicated with.When by catcher 110 in collecting chamber 120 from high-order 601 to the motion of low level 602 after, fluid sample is collected in collecting chamber 120, now, sample can enter into testing element 403 by the passage that applicator 110 is communicated with fluid-phase, completes detection.Also directly can enter into the testing element 403 be connected with collecting chamber 120, complete detection.
In some specific embodiments, after applicator 110 is positioned at collecting chamber 120 low level 602, can be kept and be locked in this position.Such as, applicator 110 and collecting chamber 120 there is respectively the circumference complemented one another screw in and circumference reception screw thread, when applicator 110 is at low level 602, the engagement threads of the two.Or can use the shutoff device complemented one another, when low level 602, padlock is sealed, ensure that applicator is kept and locks in collecting chamber.In one more specifically embodiment, the applicator portion of being affectedly bashful is replaced by a lid 101, as Fig. 2, this lid has the circumference supporting with collecting chamber screw in screw thread.When applicator 110 arrives collecting chamber low level 602, lid 101 screws on screw thread and collecting chamber 120 and receive the supporting joint of screw thread.
The present invention also provides collection to collect simultaneously, and detection and store fluid sample are in the device of one.This device comprises applicator 110, and catcher can be made up of piston 103 and absorption piece 105; Receive the collecting chamber 120 of fluid sample, collecting chamber comprises test chamber outlet 412 and reservoir outlet 413; With the Plug Division 130 that collecting chamber is supporting; Test chamber 402; A testing element 403 is at least comprised in test chamber 402; For reservoir compartment 401 and the base 140 of reservoir fluid sample; And potted component 104, sealing element 104 can be positioned on catcher 110, further, can be positioned on piston 103 outer surface of applicator.Same, applicator 110 has high-order 601 and low level 602 in collecting chamber 120; When applicator is positioned at high-order 601, collecting chamber 120 medial wall 201 contacts with potted component 104 and is formed and seals, and form a cavity, absorption piece 105 is positioned at this cavity.When applicator 110 is positioned at low level 602, cavity and the absorption piece 105 of collecting chamber 120 are compressed, and fluid sample is compressed in collecting chamber 120.This cavity also can be seal chamber, and such fluid sample is collected more abundant.
In order to realize storing sample, the function of sample can be detected again, in some embodiments, the supporting with it Plug Division 130 of collection well 120 can be rotated, when collecting chamber 120 is positioned at primary importance 406, as Fig. 3 a, shown in Fig. 4 a and Fig. 5 a, collecting chamber 120 is connected with reservoir compartment 401, and now test chamber 402 is not communicated with collecting chamber 120, and the sample being arranged in collecting chamber flow into reservoir compartment by reservoir outlet 412.When collecting chamber 120 is positioned at the second position 407, as shown in Figure 6 a, collecting chamber 120 is connected with test chamber 402, and now reservoir compartment 401 is closed, and is not communicated with collecting chamber 120; Fluid sample in collecting chamber 120 flows into test chamber 402 by test chamber outlet 413, is communicated with, completes corresponding detection with testing element 403.
In order to more effective collection fluid sample, in an embodiment, collecting chamber 120 can be divided into upper cavity 202 and lower chamber 203 by baffle plate, and upper and lower cavity is communicated with by aperture; Seal chamber and absorption piece 105 are positioned at upper cavity 202.Collecting chamber lower chamber 203 is provided with test chamber outlet 412 and reservoir outlet 413.After applicator moves to low level 602, as shown in figure 5 a and 5b, after fluid specimen collection to collecting chamber upper cavity 202, lower chamber 203 is flow into by aperture, in two outlets 412 by lower chamber, 413 are communicated with test chamber 402 with reservoir compartment 401 respectively, thus complete storage liquid and detection.After fluid sample flows into lower chamber 203, sample effectively can be stoped to be back to again in absorption piece, increase the collecting amount of sample.
In one more specifically embodiment, in order to ensure that fluid sample has enough reserves, simultaneously, also in order to ensure the accuracy of testing result, when collecting chamber 120 is when collecting fluid sample, namely, when catcher 110 moves by high-order 601 to low level 602 and compresses absorption piece 105 in collecting chamber 120 upper cavity 202, this collecting chamber 120 is positioned at primary importance 406, is namely connected with reservoir compartment 401.Now, the fluid sample be collected in upper cavity 202 is flow in lower chamber 203 by the aperture on baffle plate, then flow into reservoir compartment 401 by lower chamber reservoir outlet 413.In lower chamber 203, export 412 corresponding positions at test chamber, can be provided with part projection, when fluid sample flow in lower chamber 203, part sample is retained in test chamber and exports 412 regions because of projection.Then, after in lower chamber 203, the sample in other regions flow into reservoir compartment 401, rotate collecting chamber 120 to the second position 407, test chamber outlet 412 in lower chamber 203 is connected with test chamber 402, be retained in the fluid sample that lower chamber test chamber exports 412 regions and flow into test chamber 402 by test chamber outlet 412, infiltrate testing element 403, thus complete test.
In one embodiment, applicator 110 is contrary with the rotation direction that the primary importance 406 being threaded into direction and collecting chamber of supporting collecting chamber 120 turns to the second position 407.After applicator 110 puts into collecting chamber 120, after moving to low level 602 by high-order 601, the circumference of circumference screw-in screw thread on collecting chamber 120 namely on catcher 110 receives screw thread and is combined completely, and now, catcher 110 and collecting chamber 120 are connected as a single entity.Rotate catcher 110 or collecting chamber 120 along screw-in direction again, collecting chamber 120 can not rotate, and namely collecting chamber can not turn to the second position 407 from primary importance 406.Only have counter-rotation collecting chamber 120, it just can be made from primary importance 406 to the second position 407.Like this, can effectively prevent catcher 110 from engaging rear drive collecting chamber 120 with collecting chamber 120 to the second position 407, thus the testing result causing a large amount of fluid sample to enter test chamber in advance and produce is inaccurate.
Usually, after detection Different categories of samples, need again to carry out confirmation and detect, our reservoir compartment 401 is stored sample and is namely met this demand.Conveniently sample, in some embodiments, reservoir compartment 401 arranges a sample tap, as shown in Figure 2.In one more specifically embodiment, in order to once get enough confirmatory samples, bottom the reservoir compartment of sample tap 405 correspondence, there is a groove 411, as shown in Fig. 3 b profile.After sample flow into reservoir compartment 401, major part focuses on groove 411 place, like this, is sampled by sample tap on base 405, just can collect more fluid sample.

Claims (15)

1., for collecting a device for fluid sample, it comprises:
Applicator, this applicator comprises the compressible absorption piece for collecting fluid sample;
Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom;
Potted component;
Applicator has a high position and low level in collecting chamber; When applicator is positioned at a high position, the sidewall contact in potted component and collecting chamber also forms sealing, bottom this collecting chamber and the cavity that forms of sidewall and potted component be the cavity of a sealing, absorption piece is positioned at this cavity and is not compressed; When catcher moves to low level by a high position in collecting chamber, this cavity is compressed, and space reduces, and the air therefore in cavity and absorption piece are also compressed, and in absorption piece, fluid sample is squeezed out and flows out in collecting chamber because of the compression of absorption piece.
2. device as claimed in claim 1, it is characterized in that, when applicator is positioned at low level, potted component contacts with the medial wall of collecting chamber and is formed and seals; Cavity and absorption piece are compressed, and the fluid sample on absorption piece is collected in collecting chamber.
3. device as claimed in claim 2, it is characterized in that, potted component moves along collecting chamber medial wall along with diminishing of cavity, and keeps the sealing with medial wall always.
4. device as claimed in claim 3, it is characterized in that, potted component is positioned in applicator.
5. device as claimed in claim 4, it is characterized in that, a piston is positioned in applicator, and piston has a high position and low level; When piston is positioned at a high position, applicator is positioned at a high position for collecting chamber; When piston is positioned at low level, applicator is positioned at the low level of collecting chamber.
6. device as claimed in claim 5, it is characterized in that, piston is positioned at above absorption piece, and potted component is positioned in piston circumferential exterior surface.
7. device as claimed in claim 6, it is characterized in that, potted component is "O" ring.
8. device as claimed in claim 7, it is characterized in that, collecting chamber medial wall cross section is trapezium structure, and the trapezoidal side of a collecting chamber high position is greater than the trapezoidal side of low level.
9. preserve and a device for test fluid sample, comprising:
Applicator, this applicator comprises the compressible absorption piece for collecting fluid sample;
Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom, and it comprises test chamber outlet and reservoir outlet;
Test chamber, at least comprises a testing element in test chamber;
Plug Division, cooperatively interacts with collecting chamber;
Reservoir compartment, for storing the fluid sample of collection;
Potted component, for sealing collecting chamber;
Applicator has a high position and low level in collecting chamber, and when applicator is positioned at a high position, the sidewall contact in potted component and collecting chamber also forms sealing; The cavity formed with sidewall and potted component bottom this collecting chamber is the cavity of a sealing, and absorption piece is positioned at this cavity and is not compressed; When catcher moves to low level by a high position in collecting chamber, this cavity is compressed, and space reduces, and the air therefore in cavity and absorption piece are also compressed, and in absorption piece, fluid sample is squeezed out and flows out in collecting chamber because of the compression of absorption piece.
10. device as claimed in claim 9, is characterized in that, when applicator is positioned at low level, the sidewall contact in potted component and collecting chamber also forms sealing; Cavity and absorption piece are compressed, and the fluid sample on absorption piece is collected in collecting chamber.
11. devices as claimed in claim 10, is characterized in that, this collection well is rotatable, and when collecting chamber is positioned at primary importance, collecting chamber is connected with reservoir compartment; When collecting chamber turns to the second position, collecting chamber is connected with test chamber.
12. devices as claimed in claim 11, it is characterized in that, can be divided into upper cavity and lower chamber in collecting chamber, upper and lower cavity is communicated with by aperture; Seal chamber and absorption piece are positioned at upper cavity; Lower chamber is provided with test chamber outlet and reservoir outlet.
13. devices as claimed in claim 12, is characterized in that there is a groove in sample tap corresponding position bottom reservoir compartment.
14. devices as claimed in claim 11, is characterized in that, applicator comprises circumference and screws in screw thread, and collecting chamber comprises circumference reception screw thread; When applicator is in low level, screws in screw thread and receive engagement threads.
15. devices as claimed in claim 14, is characterized in that, collecting chamber is contrary with the screw-in direction of applicator and collecting chamber matching thread to the rotation direction of the second position by primary importance.
CN201010276019.0A 2010-09-06 2010-09-06 Device for collecting fluid samples Active CN102379724B (en)

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WO2022207890A1 (en) * 2021-04-02 2022-10-06 Ng Biotech Device for rapid analysis of a biological sample, for example a salivary biological sample
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