CN102379724A - Device for collecting fluid samples - Google Patents

Device for collecting fluid samples Download PDF

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Publication number
CN102379724A
CN102379724A CN2010102760190A CN201010276019A CN102379724A CN 102379724 A CN102379724 A CN 102379724A CN 2010102760190 A CN2010102760190 A CN 2010102760190A CN 201010276019 A CN201010276019 A CN 201010276019A CN 102379724 A CN102379724 A CN 102379724A
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China
Prior art keywords
collecting chamber
applicator
chamber
cavity
absorption piece
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CN2010102760190A
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Chinese (zh)
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CN102379724B (en
Inventor
胡海鹏
杨华强
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ABON Biopharm Hangzhou Co Ltd
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ABON Biopharm Hangzhou Co Ltd
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Abstract

The invention provides a device for collecting fluid samples. The device comprises a sample collector, a sealing element and a collecting cavity, wherein the sample collector comprises a compressible absorbing part for collecting the samples; the sealing element is used for sealing the collecting cavity; the collecting cavity is used for receiving the sample collector; the sample collector is provided with a high position and a low position in the collecting cavity; when the sample collector is located at the high position, the sealing element and the side wall in the collecting cavity are in contact to form sealing; and the sealing element forms a cavity in the collecting cavity, and the absorbing part is arranged in the cavity. The invention also provides a device for detecting the fluid samples, comprising the device for collecting the samples and a detecting element; and the detecting device can be also provided with a fluid storage cavity so as to integrate collection, detection and fluid storage into a whole. The devices provided by the invention can be used for collecting enough fluid samples so as to complete collection, detection and sample storage smoothly.

Description

A kind of device that is used to collect fluid sample
Technical field
The present invention relates to the fluid sample gathering-device, and checkout gear, especially have the gathering-device and the checkout gear of the cavity of collected fluid sample.
Background technology
Following background technology is used to help reader understanding the present invention, and can not be considered to prior art.
In our society, illicit drug use has become a social problem that generally acknowledges and worsen day by day.2003, the U.S. Department of Health and Human Service investigation found have 1,950 ten thousand Americans or 8.2% age sucking illegal medicine the crowd more than 12 years old approximately." use illegal medicine recently " and be meant to investigate in previous month and used a kind of illegal medicine at U.S. Department of Health and Human Service.Fructus Cannabis is found to be the most frequently used illegal medicine, accounts for 6.2% (1,460 ten thousand).Estimate that 2,300,000 people (1.0%) are using cocaine now, 604,000 people have used KUAIKE, have 1,000,000 people to use hallucinogen, and estimate that 119,000 people are using heroin.
In order to hit drug dependence and this social problem of monitoring, drug test is for example employed in every profession and trade, education, physical culture, law enforcement etc. have become the standard detection program.In order to promote this effort, the drug test industry forms.This industry provides various drug test product.Can to the A urine sample collection device cup that sample is analyzed the test products of a classics.These devices possibly be complicated, difficulty or dirty concerning user, or for concealing the situation of using illegal medicine recently, the problem that may cause sample to mingle.In addition, urine sample can't be collected in some occasion, for example in the roadside or the public arena.
Therefore need better method and device that sample is collected and detected.U.S. Pat 2004/0184954 just discloses other devices of collecting saliva and detecting with US2004/0237674.In these two patents, the apparatus and method of collecting and detect saliva all are provided, in these devices, after sample is sampled on the catcher, through applying external force the sample in the absorption piece on the catcher is expressed in the collecting chamber, and then detects.But sample can not all be extruded in the collecting chamber, saliva sample especially, and foam is many, and viscosity is high, and collecting amount reduces especially greatly; Thereby influence the detection of this fluid sample, perhaps no unnecessary sample is used for confirming after the pattern detection.
Summary of the invention
In order to address this problem, the present invention provides a kind of device of new collection fluid sample, and this installs by applicator, and potted component and collecting chamber are formed.Applicator comprises the compressible absorption piece that is used to collect fluid sample; Collecting chamber is used to receive applicator and fluid sample, and this collecting chamber is made up of sidewall and bottom; Applicator has a high position and low level in collecting chamber; When applicator was arranged in collecting chamber high-order, potted component contacted and forms sealing with sidewall in the collecting chamber; The sealing element forms a cavity in collecting chamber, absorption piece is positioned at this cavity.
When the absorption piece that has fluid sample is put in the collecting chamber, when just catcher was positioned at a high position, potted component contacted with the collecting chamber medial wall and forms sealing; At this moment, bottom potted component and collecting chamber medial wall and collecting chamber, form a cavity, absorption piece is positioned at this cavity; Simultaneously; The fluid sample that adsorbs on the absorption piece also is positioned at this cavity, and at this moment, absorption piece is not compressed.Because potted component and collecting chamber medial wall form sealing, therefore, when use external force made the fluid sample on the absorption piece flow in the collecting chamber, fluid sample can not flow out along the collecting chamber medial wall or be exuded to the cavity outside, guarantees the sample size that collection is enough.
When applicator was arranged in the low level of collecting chamber, potted component still contacted and forms sealing with the interior sidewall of collecting chamber; Cavity and absorption piece that potted component and collecting chamber form are compressed, and the fluid sample on the absorption piece is received in the collecting chamber.
When catcher moved to low level by a high position in collecting chamber, this cavity was compressed, and the space reduces, so the intravital air in chamber and absorption piece also be compressed, and fluid sample is squeezed out and flows out in the collecting chamber because of the compression of absorption piece in the absorption piece.In whole compression process, potted component moves along the collecting chamber medial wall along with diminishing of cavity, and the sealing of maintenance always and medial wall.Therefore, in compression process, do not have fluid sample yet and be leaked to the outside, guaranteed the abundant collection of fluid sample, collect insufficient problem thereby solved fluid sample through potted component and collecting chamber medial wall seals at.
In some embodiments, when applicator was arranged in a collecting chamber high position, potted component contacted and seals with the interior sidewall of collecting chamber, and the cavity that this collecting chamber bottom and sidewall and potted component constitute is a hermetic cavity body.Like this, be positioned at inner absorption piece after being compressed, promptly after applicator moved to low level from a high position, absorption piece was compressed very thoroughly, thereby fluid sample is as much as possible is extruded.
In some embodiments, potted component can be positioned on the applicator, along with applicator is moved in collecting chamber together.When applicator is positioned at when collecting a control high position and low level, is positioned at potted component on the applicator and contacts with the collecting chamber medial wall and seal collecting chamber.
In a specific embodiment, a piston is positioned on the applicator, and piston has a high position and low level; When piston was positioned at a high position, applicator was positioned at the high position of collecting chamber; When piston was positioned at low level, applicator was positioned at the low level of collecting chamber.Piston is positioned at the absorption piece top more specifically in the embodiment at one, and potted component is positioned on the piston circumferential exterior surface, and when piston was positioned at collecting chamber with collection well, the potted component on the piston formed with the collecting chamber medial wall and seals.
Potted component used in the present invention can be the rubber-like sealed material for playing the parts of sealing function.In the embodiment, potted component is O shape ring.
In order to guarantee better sealing effectiveness, in some embodiments, the collecting chamber medial wall can be designed with the gradient, and its gradient increases along a collecting chamber high position to low level gradually; Promptly the cross section of this medial wall be trapezoidal
Figure BSA00000261921800031
wherein; Trapezoidal top is that collecting chamber is high-order; Trapezoid bottom is the collecting chamber low level, and trapezoid top is greater than trapezoid bottom.Along with the increase of the gradient, potted component and the sealing of collecting chamber medial wall are tighter, thereby sealing property is better.
In some embodiments, applicator can be locked and remain in the collecting chamber during low level in collecting chamber.In a concrete embodiment, applicator comprises circumferential screw-in screw thread, and collecting chamber comprises circumferential reception screw thread; When sample divider is in low level, screws in screw thread and receive engage threads.
In further embodiments; Applicator can also include a lid; Circumferential screw-in screw thread is arranged on the lid, with on the collecting chamber circumferentially to accept screw thread supporting, when applicator is positioned at low level; Circumferentially accept engage threads on the screw thread of lid and the collecting chamber, applicator and collecting chamber are bonded together.
Absorption piece among the present invention is to be suitable for being placed on the sponge in person under inspection's mouth; And fluid sample can be a saliva.In one embodiment, the mouth of applicator being put into the tester carries out sample collection, makes catcher be full of saliva.
The present invention also provides a kind of fluid sample checkout gear, comprises fluid collection device and testing element.Specifically comprise applicator, this applicator comprises the compressible absorption piece that is used to collect fluid sample; Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom; Potted component is used to seal collecting chamber; Testing element is positioned on the applicator or collecting chamber; Same, applicator has a high position and low level in collecting chamber; When applicator was arranged in collecting chamber high-order, potted component contacted and forms sealing with the collecting chamber medial wall; Potted component and collecting chamber form a cavity, and absorption piece is positioned at cavity.When applicator was arranged in the low level of collecting chamber, potted component still contacted and forms sealing with the collecting chamber medial wall; Cavity and absorption piece that potted component and collecting chamber form are compressed, and the fluid sample on the absorption piece is received in the collecting chamber.
In certain embodiments, testing element is positioned at collecting chamber, is connected with fluid sample through path.In further embodiments, testing element is positioned on the applicator, and testing element is communicated with the absorption piece fluid through the passage in the applicator that connects absorption piece and testing element.
On the other hand, the present invention also provides the sample testing apparatus with liquid storage function, comprising: applicator, this applicator comprise the compressible absorption piece that is used to collect fluid sample; Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom, and this collecting chamber also comprises test chamber outlet and reservoir compartment outlet; Test chamber; At least comprise a testing element in the test chamber; The Plug Division cooperatively interacts with collecting chamber; Reservoir compartment; Be used to store the fluid sample of collection; Potted component is used to seal collecting chamber; Reservoir compartment and test chamber are connected with collection well through corresponding outlet on the collecting chamber.Applicator has a high position and low level in collecting chamber; When applicator was arranged in collecting chamber high-order, potted component contacted and forms sealing with the collecting chamber medial wall; Potted component and collecting chamber form a cavity, and absorption piece is positioned at cavity.When applicator was arranged in the low level of collecting chamber, potted component still contacted and forms sealing with the collecting chamber medial wall; Cavity and absorption piece that potted component and collecting chamber form are compressed, and the fluid sample on the absorption piece is received in the collecting chamber.
In some embodiments, the cavity of potted component and collecting chamber formation can seal.
In other modes, potted component can be positioned on the applicator.In the more excellent embodiment, a piston also is positioned on the applicator, and is positioned at the top of absorption piece, and potted component is then on the circumferential exterior surface of piston.Piston, absorption piece and potted component have a high position to the low level motion along with catcher together in collecting chamber, and when motion, potted component keeps sealing with the collecting chamber medial wall always.
Equally, in some embodiments, the collecting chamber medial wall also can be designed with the gradient, and its gradient increases along a collecting chamber high position to low level gradually.Promptly the cross section of this medial wall be trapezoidal
Figure BSA00000261921800041
wherein; Trapezoidal top is that collecting chamber is high-order, and trapezoid bottom is the collecting chamber low level.Along with the increase of the gradient, potted component and the sealing of collecting chamber medial wall are tighter, thereby sealing property is better.
In certain embodiments, collection well and supporting with it connector can rotate, and when turning to primary importance, collecting chamber is connected with reservoir compartment, and this moment, test chamber was not communicated with collecting chamber; When turning to the second position, collecting chamber is connected with test chamber, and reservoir compartment is communicated with collecting chamber.
Applicator and collection well can have supporting screw-in or screw out screw thread, and for fool proof, the screw-in direction of this matching thread and collecting chamber primary importance turn to the in the opposite direction of the second position.
For more effective collection fluid sample, collection well can be provided with two cavitys up and down, and the centre separates with plate washer, and absorption piece is positioned at the cavity of potted component and upper cavity formation.Cavity is provided with aperture and is connected up and down.When absorption piece is compressed in the upper cavity, fluid sample is extruded and flow to lower chamber through aperture, effectively stops fluid sample to be back in the absorption piece, has guaranteed to collect more fully sample.Lower chamber is provided with reservoir compartment outlet and test chamber outlet.When collecting chamber turned to primary importance, the outlet of collecting chamber lower chamber reservoir compartment was communicated with reservoir compartment, and collecting chamber inner fluid sample flow in the reservoir compartment through this outlet; When collecting chamber turned to the second position, the outlet of collecting chamber lower chamber test chamber was communicated with test chamber, and the collecting chamber sample flow into test chamber through the test chamber outlet, contacts with testing element, accomplishes and detects.
Take out the storage sample of reservoir compartment for ease, the corresponding position can be provided with sample tap above reservoir compartment on the base.In order to obtain abundant storage sample, the reservoir compartment bottom corresponding at sample tap can be provided with a groove, and the sample in the reservoir compartment more concentrates on groove, convenient sampling.
Beneficial effect
Gathering-device provided by the invention increases compressing force and can effectively stop sample to leak, thereby can collect abundant liquid sample because of the space of collection liquid sample with sealing.
Description of drawings
Fig. 1 is the schematic perspective view of a device of the present invention
Fig. 2 is the STRUCTURE DECOMPOSITION figure of Fig. 1 device
Fig. 3 to Fig. 6 is the operation chart and the Operation Profile sketch map of device according to the invention
Fig. 3 a, Fig. 3 b are the sketch map before applicator is put into collecting chamber
Fig. 4 a, Fig. 4 b are the sketch map that applicator is put into collecting chamber (promptly high-order)
Fig. 5 a, Fig. 5 b are the low level sketch map of applicator, and collecting chamber is positioned at the primary importance sketch map simultaneously
Fig. 6 a, Fig. 6 b are that collection well is positioned at second position sketch map
Fig. 7 is that testing element is positioned at the sketch map on the applicator
Description of reference numerals
Applicator 110; Lid or be affectedly bashful portion 101; Pillar 102; Piston 103; Potted component 104; Absorption piece 105; Collecting chamber 120; With the supporting Plug Division 130 of collecting chamber, comprise the base 140 of test chamber and liquid storage cylinder; Liquid storage cylinder 401; Test chamber 402; Testing element 403, sample tap 405, liquid storage cylinder groove 411, the catcher high position 601 in collecting chamber; The low level 602 of catcher in collecting chamber; Collecting chamber medial wall 201; Collecting chamber primary importance 406, the collecting chamber second position 407; Reservoir compartment outlet 412; Test chamber outlet 413; Collecting chamber upper cavity 202; Collecting chamber lower chamber 203
Do further explanation in the face of structure or these employed technical terms of liquid-sample collection device down.
Sample
The sample of indication of the present invention refers to that those can be used for detecting, chemically examining or diagnose the material that whether has analyte of interest matter.Sample can be a fluid sample, and for example, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise that solid sample and semi-solid samples are through anticipating the liquid solution that the back forms.The sample of collecting can be used for methods such as immune detection, chemical detection, enzyme detection and detect whether there is analyte.
Testing element
" testing element " is any element of carrying out test.In one embodiment, testing element is a test strip.This test strip can comprise be used for above that immunoassay to have a bonded material of specificity right.Test strip can be a kind of test chemical bar that after detecting completion, passes through change color or other signals variation judged results.The sample that suitable the present invention detects includes but not limited to body fluid, separated sample from biological tissue or body fluid.For example, sample can be a saliva, blood, serum, blood plasma, urine, Excreta, spinal fluid, vaginal secretion, mucus and tissue.Testing element is not limited to one, can be that two or more testing elements are arranged in checkout gear simultaneously, respectively different component in the test sample book.
Applicator
The present invention also provides applicator 110.In one embodiment, applicator 110 has an absorber element 105 and is affectedly bashful portion 101.Absorber element 105 is processed by this area other sponge of medical grade or plastic foam material commonly used usually.But many other materials also can be made into absorber element, for example Cotton Gossypii or paper, perhaps other any materials with water absorbing properties.Applicator can be in advance soaked containing can stimulate in the salivary solution of tester.Thereby make and when catcher is put into tester's mouth, collect saliva more easily.The portion of being affectedly bashful is normally inflexible, helps the operation to absorber element.The portion of being affectedly bashful can be processed by this area material commonly used, for example plastics, timber, metal or cardboard.Among the embodiment, the portion top of being affectedly bashful can be a lid form, forms matching thread with collecting chamber.Among another embodiment, a testing element is connected on the catcher, and absorption piece is having path to be connected with testing element.
The specific embodiment
In following detailed description, the explanation of accompanying drawing and corresponding character only is a mode of explaining that by way of example the present invention can actable specific concrete scheme.We do not get rid of the present invention can also be in any other specific embodiment in claim scope of the present invention.
Gathering-device advantage provided by the present invention is fully to collect liquid sample, and particularly viscosity is high, the saliva equal samples that foam is many.As depicted in figs. 1 and 2, this gathering-device basic structure is by applicator 110, and collection well 120 and potted component 104 constitute.Applicator 110 comprises absorption piece 105, and the pillar 102 of being affectedly bashful portion 101 and connecting the two is affectedly bashful portion 101 and also can be designed to the lid supporting with collecting chamber 120.Potted component 104 can be placed in the collecting chamber 120, such as " O " type circle that invests on collecting chamber 120 medial walls; Also can be connected on the applicator 110, when potted component 104 is positioned at 110 last times of applicator, need be placed on absorption piece 105 and be affectedly bashful portion or lid 101 between.In the specific embodiment, potted component 104 is attached on the pillar 102 of catcher 110, is connected together with absorption piece 105.
In a concrete embodiment, the absorption piece 105 of applicator 110 is put into tester's mouth collect sample.Like Fig. 3 a sketch map and Fig. 3 b generalized section, the catcher 110 after the sampling is put into collection well 120, at this moment; Absorption piece 105 and collecting chamber 120 pig, promptly catcher 110 is positioned at the high position 601 of collecting chamber 120, shown in Fig. 4 a; See specifically shown in Fig. 4 b profile that at this moment, potted component 104 contacts and form sealing with collecting chamber medial wall 201; And forming a cavity, absorption piece 105 is not compressed in cavity.When catcher 110 further to collecting chamber 120 internal motions to collecting chamber bottom; When being low level 602, shown in Fig. 5 b profile, at this moment; Potted component 104 also moves to low level 602 by high-order 601 along with catcher 110 together, and keeps contacting and sealing with collecting chamber medial wall 201 always.Potted component 104 dwindles along with the motion of catcher 110 with the cavity that collecting chamber 120 forms, and the absorption piece 105 that is positioned at this intracavity is compressed, thereby the fluid sample that invests absorption piece 105 just enters in the collection well 120.
In another specific embodiment, high-order 601 the time in collecting chamber when applicator 110, potted component 104 can seal with the cavity that collecting chamber 120 forms.Like this in compression during this cavity, because of space sealing, intrinsic pressure increase, it is more thorough that absorption piece is extruded, and fluid sample then more to be extruded.
In other embodiments; In order to accelerate compression chamber or seal chamber, a piston 103 is positioned on the applicator 110, and is as shown in Figure 2; Move in collecting chamber 120 with applicator 110; Piston 103 is synchronous with applicator 110, and when piston 103 was positioned at a high position, applicator 110 also was arranged in the high position of collecting chamber 120; Equally, when piston 103 moved to low level, applicator 110 also was positioned at low level.More specifically among the embodiment, piston 103 is positioned on the catcher pillar 102 at another, and is adjacent with absorption piece 105 and be positioned at absorption piece 105 tops, and simultaneously, potted component 104 is positioned on the piston 103; Be positioned on piston 103 circumferential exterior surface such as potted component 104, as shown in Figure 2.When catcher 110 was arranged in collecting chamber 120, the potted component 104 that is positioned on the piston formed sealing with collecting chamber medial wall 201, and when catcher moved to low level 602 by high-order 601, potted component 104 contacted and form sealing with collecting chamber medial wall 201 always.
In other embodiments, in order to guarantee better sealing effectiveness, collection well medial wall 201 is designed with the gradient, and the gradient promptly increases to low level 602 along the high position 601 of applicator 110 in collecting chamber along increasing gradually in the outer course gradually.Just this collecting chamber cross section is a ladder diagram, and the high-order trapezoidal side of this collecting chamber is greater than the trapezoidal side at collecting chamber low level place.Like this, rubber-like potted component 104 with collecting chamber medial wall 201 motion the time, big-endian, the gradient increases gradually, elastic potted component 104 is compressed more, and is tightr with medial wall 102 sealings, thus sealing property is better.
The present invention is providing on the basis of collecting fluid sample, also provides and detects the device that these collect sample, comprises applicator 110, potted component 104, collecting chamber 120 and testing element 403.Wherein, testing element 403 can be connected on the applicator 110 and with absorption piece 105 fluids and be connected, and is as shown in Figure 7; Also can directly be placed in the collecting chamber 120 or and be communicated with collecting chamber 120.When through catcher 110 in collecting chamber 120 from high-order 601 after the motion of low level 602; Fluid sample is collected in the collecting chamber 120; At this moment, sample can enter into testing element 403 through the passage that is connected with fluid on the applicator 110, accomplishes and detects.Also can directly enter into the testing element 403 that links to each other with collecting chamber 120, accomplish and detect.
In some concrete embodiment, applicator 110 can be held and be locked in this position after being positioned at collecting chamber 120 low levels 602.For example, the circumferential screw-in that complements one another is arranged respectively on applicator 110 and collecting chamber 120 and circumferentially receive screw thread, when applicator 110 during at low level 602, the engage threads of the two.Perhaps, can use the shutoff device that complements one another, when low level 602, padlock is sealed, has guaranteed that applicator is held in collecting chamber and locks.At one more specifically in the embodiment, a lid 101 is replaced by in the applicator portion of being affectedly bashful, and like Fig. 2, the circumferential screw-in screw thread supporting with collecting chamber is arranged on this lid.When applicator 110 arrives collecting chamber low levels 602, screw on screw thread and the collecting chamber 120 reception on the lid 101 screw thread is supporting and engage.
The present invention also provides collection to collect simultaneously, and detection and store fluid sample are in the device of one.This device comprises applicator 110, and catcher can be made up of piston 103 and absorption piece 105; Receive the collecting chamber 120 of fluid sample, collecting chamber comprises test chamber outlet 412 and reservoir compartment outlet 413; With the supporting Plug Division 130 of collecting chamber; Test chamber 402; At least comprise a testing element 403 in the test chamber 402; The reservoir compartment 401 and base 140 that are used for the reservoir fluid sample; And potted component 104, sealing element 104 can be positioned on the catcher 110, further, can be positioned on piston 103 outer surfaces of applicator.Same, applicator 110 has a high position 601 and low level 602 in collecting chamber 120; When applicator is positioned at high-orderly 601 the time, collecting chamber 120 medial walls 201 contact and form sealing with potted component 104, form a cavity, and absorption piece 105 is positioned at this cavity.When applicator 110 was positioned at low level 602, the cavity of collecting chamber 120 and absorption piece 105 were compressed, and fluid sample is compressed in the collecting chamber 120.This cavity also can be a seal chamber, and fluid sample is collected more fully like this.
In order to realize to store sample, can detect the function of sample again, in some embodiments; The supporting with it Plug Division 130 of collection well 120 can be rotated, when collecting chamber 120 is positioned at primary importance 406, like Fig. 3 a; Shown in Fig. 4 a and Fig. 5 a; Collecting chamber 120 is connected with reservoir compartment 401, and this moment, test chamber 402 was not communicated with collecting chamber 120, and the sample that is arranged in collecting chamber flow into reservoir compartment through reservoir compartment outlet 412.When collecting chamber 120 was positioned at the second position 407, shown in Fig. 6 a, collecting chamber 120 was connected with test chamber 402, and this moment, reservoir compartment 401 was closed, and was not communicated with collecting chamber 120; Fluid sample in the collecting chamber 120 flows into test chamber 402 through test chamber outlet 413, is communicated with testing element 403, accomplishes relevant detection.
For more effective collection fluid sample, in the embodiment, collecting chamber 120 can be divided into upper cavity 202 and lower chamber 203 by baffle plate, and cavity is communicated with through aperture up and down; Seal chamber and absorption piece 105 are positioned at upper cavity 202.Collecting chamber lower chamber 203 is provided with test chamber outlet 412 and reservoir compartment outlet 413.After applicator moves to low level 602; Shown in Fig. 5 a and Fig. 5 b; After fluid sample is collected collecting chamber upper cavity 202, flow into lower chamber 203, in two outlets 412 through lower chamber through aperture; 413 are communicated with reservoir compartment 401 and test chamber 402 respectively, thereby accomplish storage liquid and detection.After fluid sample flows into lower chamber 203, can effectively stop sample to be back to again in the absorption piece, increase the collecting amount of sample.
At one more specifically in the embodiment; In order to guarantee that fluid sample has enough reserves, simultaneously, also in order to guarantee the accuracy of testing result; When collecting chamber 120 when collecting fluid sample; Promptly when catcher 110 in collecting chamber 120 upper cavities 202 by high-order 601 during to low level 602 motions and compression absorption piece 105, this collecting chamber 120 is positioned at primary importance 406, promptly is connected with reservoir compartment 401.At this moment, the fluid sample that is collected in the upper cavity 202 flow in the lower chamber 203 through the aperture on the baffle plate, flow into reservoir compartment 401 through lower chamber reservoir compartment outlet 413 again.In lower chamber 203, export 412 corresponding positions at test chamber, can be provided with the part projection, when fluid sample flow in the lower chamber 203, the part sample exported 412 zones because of projection is retained in test chamber.Then; After other regional samples flow into reservoir compartment 401 in the lower chamber 203; Rotate collecting chamber 120 to the second position 407, test chamber outlet in the lower chamber 203 412 is connected with test chamber 402, and the fluid samples that are retained in lower chamber test chamber outlet 412 zones export 412 through test chamber and flow into test chamber 402; Soak into testing element 403, thereby accomplish test.
In one embodiment, applicator 110 and the primary importance that is threaded into direction and collecting chamber 406 of supporting collecting chamber 120 turn to the direction of rotation of the second position 407.After applicator 110 is put into collecting chamber 120, move to low level 602 by high-order 601 after, promptly the circumferential screw-in screw thread on the catcher 110 combines with circumferential reception screw thread on the collecting chamber 120 fully, at this moment, catcher 110 and collecting chamber 120 are connected as a single entity.Rotate catcher 110 or collecting chamber 120 along screw-in direction again, collecting chamber 120 can not rotate, and promptly collecting chamber can not turn to the second position 407 from primary importance 406.Have only counter-rotation collecting chamber 120, just can make it from primary importance 406 to the second position 407.Like this, can prevent effectively that catcher 110 from engaging the back and driving collecting chamber 120 to the second position 407 with collecting chamber 120, thereby cause the quantity of liquid sample to get into test chamber in advance and the testing result that produces is inaccurate.
Usually, after detecting all kinds of samples, need confirm once more to detect, our reservoir compartment 401 storage samples have promptly satisfied this demand.Sampling in some embodiments, is provided with a sample tap on reservoir compartment 401 for ease, and is as shown in Figure 2.At one more specifically in the embodiment,, in sample tap 405 corresponding reservoir compartment bottoms one groove 411 is arranged, shown in Fig. 3 b profile in order once to get enough affirmation samples.After sample flow into reservoir compartment 401, major part focused on groove 411 places, like this, through 405 samplings of sample tap on the base, just can collect the more fluid sample.

Claims (16)

1. device that is used to collect fluid sample, it comprises:
Applicator, this applicator comprise the compressible absorption piece that is used to collect fluid sample;
Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom;
Potted component;
Applicator has a high position and low level in collecting chamber; When applicator was positioned at a high position, potted component contacted and forms sealing with the interior sidewall of collecting chamber, and the sealing element forms a cavity in collecting chamber simultaneously, and absorption piece is positioned at this cavity.
2. device as claimed in claim 1 is characterized in that, when applicator was positioned at low level, potted component contacted and form sealing with the medial wall of collecting chamber; Cavity and absorption piece are compressed, and the fluid sample on the absorption piece is collected in the collecting chamber.
3. device as claimed in claim 2 is characterized in that, this cavity that includes absorption piece is a seal chamber.
4. device as claimed in claim 3 is characterized in that potted component is positioned on the applicator.
5. device as claimed in claim 4 is characterized in that a piston is positioned on the applicator, and piston has a high position and low level; When piston was positioned at a high position, applicator was positioned at the high position of collecting chamber; When piston was positioned at low level, applicator was positioned at the low level of collecting chamber.
6. device as claimed in claim 5 is characterized in that, piston is positioned at the absorption piece top, and potted component is positioned on the piston circumferential exterior surface.
7. device as claimed in claim 6 is characterized in that, potted component is a "O.
8. device as claimed in claim 7 is characterized in that, collecting chamber medial wall cross section is a trapezium structure, and the elevated trapezoidal side of collecting chamber is greater than the trapezoidal side of low level.
9. like the described device of one of claim 1-8, it is characterized in that catcher is positioned at elevated the time, absorption piece is not compressed.
10. preserve the also device of test fluid sample for one kind, comprise
Applicator, this applicator comprise the compressible absorption piece that is used to collect fluid sample;
Receive the collecting chamber of fluid sample, this collecting chamber is made up of sidewall and bottom, and it comprises test chamber outlet and reservoir compartment outlet;
Test chamber comprises a testing element at least in the test chamber;
The Plug Division cooperatively interacts with collecting chamber;
Reservoir compartment is used to store the fluid sample of collection;
Potted component is used to seal collecting chamber;
Applicator has a high position and low level in collecting chamber, when applicator was positioned at a high position, potted component contacted and form sealing with the interior sidewall of collecting chamber; The sealing element forms a cavity in collecting chamber simultaneously, and absorption piece is positioned at this cavity.
11. device as claimed in claim 10 is characterized in that, when applicator was positioned at low level, potted component contacted and forms sealing with the interior sidewall of collecting chamber; Cavity and absorption piece are compressed, and the fluid sample on the absorption piece is collected in the collecting chamber.
12. device as claimed in claim 11 is characterized in that, this collection well is rotatable, and when collecting chamber was positioned at primary importance, collecting chamber was connected with reservoir compartment; When collecting chamber turned to the second position, collecting chamber was connected with test chamber.
13. device as claimed in claim 12 is characterized in that, can be divided into upper cavity and lower chamber in the collecting chamber, cavity is communicated with through aperture up and down; Seal chamber and absorption piece are positioned at upper cavity; Lower chamber is provided with test chamber outlet and reservoir compartment outlet.
14. device as claimed in claim 13 is characterized in that, there is a groove reservoir compartment bottom in the sample tap corresponding position.
15. device as claimed in claim 12 is characterized in that, applicator comprises circumferential screw-in screw thread, and collecting chamber comprises circumferential reception screw thread; When applicator is in low level, screws in screw thread and receive engage threads.
16. device as claimed in claim 15 is characterized in that, collecting chamber is opposite by the screw-in direction of the rotation direction of primary importance to the second position and applicator and collecting chamber matching thread.
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