CN201417273Y

CN201417273Y - Diagnostic test device

Info

Publication number: CN201417273Y
Application number: CN2009201157599U
Authority: CN
Inventors: 胡海鹏; 吴银飞; 高飞
Original assignee: ABON Biopharm Hangzhou Co Ltd
Current assignee: ABON Biopharm Hangzhou Co Ltd
Priority date: 2009-03-18
Filing date: 2009-03-18
Publication date: 2010-03-03
Anticipated expiration: 2019-03-18

Abstract

The utility model relates to a diagnostic test device, which comprises an opening, a bottom and a cup body formed by a side wall. The cup body comprises a collection cavity used for receiving collection element and a test cavity for accommodating a test reagent strip; the collection cavity is communicated with the liquid in the test cavity; the diagnostic test device further comprises a cover usedfor sealing the opening of the cup body and connected with the collection element; the cover is provided with a first position and a second position; when the cover is positioned in the first position, the test reagent strip is not tested; and when the cover is positioned in the second position, the liquid sample is transferred from the collection cavity to the test cavity. The diagnostic test device has the advantages that the use is convenient; the collection and test can be finished at one time; the sample can not overflow to pollute the environment; and the safety of an operator can be ensured.

Description

The diagnostic detection device

Technical field

The utility model relates to a kind of diagnostic detection device, especially a kind of diagnostic detection device that detects illegal drug.

Background technology

Diagnostic detection device relatively more commonly used at present, especially the diagnostic detection device of illegal drug is collected usually and is detected separately and carry out, and needs to deposit or transport and detect after collecting, this mode program is loaded down with trivial details, and may influence the sensitivity or the accuracy of test.The diagnostic detection device of integral type, as the pick-up unit of describing among U.S. Pat 2005/0180882 A1, comprise reservoir compartment, test chamber, and with the matching used Plug Division of collecting chamber, this pick-up unit is by rotating collection well, arrives sample is transferred to purpose in the test chamber from reservoir compartment.

Summary of the invention

The utility model relates to a kind of diagnostic detection device, comprises the cup of being made up of opening, bottom and sidewall, and this cup comprises the test chamber that is used to accept the collecting chamber of gathering element and holds the detectable bar, wherein collecting chamber and test chamber fluid connection.In one embodiment, this diagnostic detection device also comprises and is used to the lid that seals the cup opening and link to each other with gathering element.In a concrete example, this lid has the primary importance and the second place, and when lid was positioned at primary importance, the detectable bar did not detect, and when lid was positioned at the second place, liquid was transferred to test chamber and start detection generation from collecting chamber.

Lid can be used to seal the cup opening of diagnostic detection device.The mode of its sealing preferably, can adopt the lid of press-button type.Specifically, a clasp is installed on lid, a clasp is installed on the sidewall of cup, clasp and clasp are worked in coordination, and can reach the purpose of sealing cup opening during cooperation.Preferred in addition, the mode of closed with covers, screw type in addition.In a specific embodiment, be respectively arranged with screw thread on the sidewall inwall of lid and cup, working in coordination between the screw thread reaches the purpose of sealing cup opening.

Lid links to each other with gathering element, therefore can realize the change of gathering element position by the change of position of cap, and liquid sample is transferred in the test chamber from gathering element.The mode of this transfer sample, the mode of preferred extruding.In one embodiment, this gathering element directly links to each other with lid, can be directly the variation of position by lid reach liquid sample is pushed the purpose of coming out from gathering element.In a concrete example, lid has two positions, and when lid was positioned at primary importance, gathering element was positioned at the bottom of cup but change of shape does not take place, and does not also have liquid sample to be squeezed out from gathering element; When lid was positioned at the second place, when just moving down, the absorbent material on the gathering element can be stopped and be extruded owing to be soft by bottom of cup, and the liquid sample of extruding is transferred in the test chamber from collecting chamber.Be more preferably, the absorbent material of lid and gathering element can link to each other indirectly by other media.Wherein preferred, be to connect absorbent material and lid with rigid material.In one embodiment, between absorbent material and lid, increase a handle, can absorbent material be connected with lid by handle.In concrete example, shown in Fig. 1-5, this handle can weld with lid, so that more firmly must fix each element.In addition, when using this handle, the tester only need contact absorbent material with sample, because the existence of handle, handled easily, and avoid other materials such as hand of operator directly to touch absorbent material, cause pollution to sample.In another concrete example, this handle can with the lid buckle on, as shown in Figure 3, handle is connected with absorbent material, the buckle of handle can be inserted in the draw-in groove in the lid, formation relatively is fixedly coupled.More preferred, the gathering element of being made up of handle and absorbent material can independent packaging, when detection needs, by handle gathering element is connected on the lid earlier, puts into cup then and detects.Very convenient in the production run of reality, this diagnostic detection device easy to use once finished from collecting detection, and sample can not overflow contaminated environment, and is relatively safe to the operator.

Description of drawings

Fig. 1 is the stereographic map of a specific embodiment of the utility model;

Fig. 2 is the three-dimensional exploded view of diagnostic detection device among Fig. 1;

Fig. 3 is the structure explosive view of diagnostic detection device among Fig. 1;

Fig. 4 is the sectional view before the diagnostic detection device detects among Fig. 1;

Sectional view when Fig. 5 carries out for diagnostic detection device among Fig. 1 detects;

Fig. 6 is that the back up pad of another embodiment is launched synoptic diagram;

Fig. 7 is the diagrammatic cross-section of another embodiment;

Fig. 8 is the diagrammatic cross-section of the 3rd embodiment.

Reference numeral:

Diagnostic detection device 1; Cup 10, cup opening 101, collecting chamber 102, test chamber 103, test chamber groove 104, baffle plate 11, through hole 110, cup inwall 12, bottom of cup 13, base projections 14, projection right side 141, projection left side 142, pore 15, detectable bar 16, back up pad 17, support column 170, draw-in groove 171, cup outer wall 18, cup screw thread 19; Lid 20, handle 21, handle holder 22, spongy top 23, buckle 24, lid screw thread 25, gathering element 26.

Embodiment

Structure or these employed technical terms to the diagnostic detection device is described further below.

Detect the expression chemical examination or test a kind of material or whether material exists, such as, but be not limited to this, the metabolin of chemical substance, organic compound, mineral compound, metabolism product, medicine or drug metabolite, organic organization or organic organization, nucleic acid, protein or polymkeric substance.In addition, detect the quantity of expression test substances or material.Furtherly, immune detection, chemical detection, enzyme detection etc. are also represented in chemical examination.

The sample of the utility model indication refers to that those can be used for detecting, chemically examining or diagnose the material that whether has analyte of interest matter.Liquid or sample can be that for example, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise that solid sample and semi-solid samples are through anticipating the liquid solution that the back forms.The sample of collecting can be used for methods such as immune detection, chemical detection, enzyme detection and detect whether there is analyte.

Diagnostic detection device 1 can comprise cup 10 and lid 20 in the utility model.In one embodiment, cup 10 is made up of opening 101, bottom 13 and sidewall 18.Preferably, cup 10 can comprise collecting chamber 102 and test chamber 103.Wherein collecting chamber 102 can be accepted gathering element 26, and test chamber 103 is used for detecting sample and whether contains analyte, collecting chamber 102 and test chamber 103 fluid connections.In one embodiment, between collecting chamber 102 and the test chamber 103, can directly communicate.Preferred mode has the bottom 13 of collecting chamber 102 and test chamber 103 shared cups.Gathering element 26 directly is inserted into bottom of cup 13, serves as to stop carrying out the extruding of liquid sample with bottom of cup 13, and the liquid sample that squeezes out is stayed bottom of cup 13, also stays in the test chamber 103.The diagnostic detection device 1 of this mode, it is very convenient to operate.In another embodiment, bottom of cup 13 has baffle plate 11, the main effect of baffle plate 11, and the one, can stop gathering element 26 to move down, the 2nd, gathering element 26 can push out with liquid sample on baffle plate.More particularly, baffle plate 11 relative bottom of cup 13 projections 14.As shown in Figure 7, the right side 141 of projection 14 and left side 142, and bottom of cup 13 also have sidewall 18 can form the groove 104 of test chamber jointly.When the gathering element 26 that will have liquid sample places on the baffle plate 11, extruding downwards then, liquid sample in the gathering element 26 can be extruded out, because baffle plate 11 exceeds bottom of cup 13 parts, sample can flow in the groove 104 of test chamber along the both sides 141,142 of projection 14.In particular, the evolution by lid 20 just varies to the second place from primary importance, makes sample in the gathering element 26 transfer to the groove 104 of test chamber.Preferably, the sample region of acceptance that detectable bar 16 and bottom of cup 13 vertical placements, the sample in the test chamber groove 104 can detected reagent strips 16 absorbs, start detection reaction then.The diagnostic detection device 1 of this mode has more succinct operating process, and is very convenient in actual applications.

In the another one specific embodiment, baffle plate 11 is formed collecting chamber 102 with the sidewall 12 and the opening 101 of cup.Wherein preferred, have the through hole 110 of circulation for liquid on the baffle plate 11.When the liquid sample collection finishes, gathering element 26 can be placed in the collecting chamber 102, after gathering element 26 is stopped by baffle plate 11, and extruding downwards again, liquid sample can be extruded from gathering element 26, be arrived test chamber 103 by the through hole in the baffle plate 11 110 then.More preferred, baffle plate 11 projections and bottom of cup 13.Test chamber 103 and collecting chamber 102 can be two cavitys of spatially isolating.The sidewall of cup comprises outer wall 18 and inwall 12.Cup inwall 12, the opening 101 of baffle plate 11 and cup is formed collecting chamber 102.As shown in Figure 3, the diagnostic detection device 1 of this form, collect liquid sample with gathering element 26 earlier, the lid 20 of gathering element 26 of will ining succession is then inserted in the collecting chamber 102, along with the threaded engagement of lid 20 and collecting chamber 102, when lid 20 thoroughly and cup when cooperating closely, the liquid sample in the gathering element 26 is owing to being extruded, just the passage between collecting chamber 102 and test chamber 103 arrives test chamber 103, and start detection reagent strip 16 detects.

Gathering element 26 can be absorptive material, and this absorbent material can be independent, also can be connected with rigid medium.In preferred mode, gathering element 26 can be the absorbent material that links to each other with lid 20, and this gathering element 26 is water wettabilities, the reasonable material of water absorptivity and water-retaining property, and liquid is extruded out again easily simultaneously.Such as some super-strong moisture absorbing macromolecular materials etc., also claim super absorbent resin, super strength water absorbent or high water absorbency polymer, comprise polyvinyl alcohol (PVA) (PVA), resin, sodium polyacrylate cross-linking agent, the AA-E acid copolymer, acrylonitrile polymerization is saponified, and vinyl alcohol all is the new functional macromolecule material with excellent water-intake capacity and water holding capacity.These materials are in water absorption course, at first by few capillary absorption and peptizaiton suction, pass through the effect of Van der Waals force between hydrogen bond and hydrophilic radical then, the hydrophilic radical disassociation, electrostatic repulsion forces between the ion makes the network expansion of hydrophilic radical, the inside and outside osmotic pressure that produces of network, moisture further infiltrates.Along with the increase of water absorbing capacity, the inside and outside osmotic pressure of network trends towards zero, and the expansion of hydrophilic radical network the time, its elastic contractile force is also increasing, and offsets anionic Coulomb repulsion gradually, finally reaches the suction balance.The macromolecular material of polyvinyl alcohol especially wherein, though water absorbent rate is not high, absorption speed is than very fast, half of the water absorbing capacity that can reach capacity in 2-3 minute.Constituting the absorbent material of gathering element 26, can also be sponge, agarose, starch based natural polymer product of chitin and so on or cellulose family natural polymer product or polysaccharide natural polymer product or protein-based natural polymer producing region etc.The gathering element 26 that this material constitutes not only can be drawn a large amount of liquid easily, and simultaneously when being subjected to the external force extruding, liquid is easy to be extruded out and detects chemical examination.

Can also comprise support component 17 in the test chamber 103.The effect of support component 17 is to make detectable bar 16 fixing and be in erectility in diagnostic detection device 1.The sample region of acceptance of detectable bar 16 is positioned at the below of marked region and surveyed area.More preferred, the sample region of acceptance of detectable bar 16 is positioned at the upstream of liquid flow direction.This support component 17 is that the specification according to detectable bar 16 is provided with.In one embodiment, support component 17 can have the draw-in groove 171 suitable with detectable bar 16 width, and detectable bar 16 can be fixed in the draw-in groove 171.In concrete example, support component 17 can paste the cup interior of diagnostic detection device 1 and settle.Preferably, according to the quantity of detectable bar 16, the quantity of draw-in groove 171 is set.More preferred, support component 17 can also comprise the support column 170 that is used to prevent 16 bendings of detectable bar, sample region of acceptance one end of detectable bar is near support column 170, support column 170 can be against the bottom 13 of diagnostic detection device 1, parallel with detectable bar 16, like this, even the sample region of acceptance of detectable bar 16 is because the absorption of liquid sample becomes soft, thereby can not influence the carrying out that reacts by bending yet.

On test chamber 103, can also comprise that one stops sample to surpass on the detectable bar 16 the obstruction ring of high scale.The existence of this obstruction ring makes liquid sample can not avoid liquid sample too much to cause the mighty torrent phenomenon above the MAX line on the reagent strip, causes the inaccurate of testing result.In specific embodiment, this obstruction ring can be selected non-water-absorbing material for use, shuts fully between the inwall 12 with support component 17 and test chamber 103, in order to avoid cause the excessive absorption of liquid sample.In another embodiment, this obstruction ring can also be the water absorptivity material, as filter paper etc., the sample of excess enthalpy is stayed stop in the ring.

Below in conjunction with concrete accompanying drawing examples of implementation of the present utility model are described in detail.These specific embodiment only are limited the enumerating under the utility model spirit, do not get rid of one of ordinary skill in the art prior art and the utility model in conjunction with and other specific embodiments of producing.

Embodiment 1

Shown in Fig. 1-5, the profile of diagnostic detection device 1 is cylindraceous, and the detection sample is a saliva.Diagnostic detection device 1 is made up of lid 20 and cup 10, and lid 20 and cup 10 can threaded engagement.Wherein be connected with the gatherer 26 of collecting saliva on the lid 20, comprise handle 21 and spongy top 23, the top of handle 21 is connected with lid buckle 24, and the bottom is that handle holder 22 and spongy top 23 are bonding.Cup 10 has double-deck wall, is divided into inwall 12 and outer wall 18.Cup 10 is divided into two chambeies, and test chamber 103 and collecting chamber 102 are respectively applied for and collect sample and detect sample.Test chamber 103 is by cup outer wall 18, and cup inwall 12 and bottom of cup 13 both sides are formed.Collecting chamber 102 comprises a baffle plate 11, includes the through hole 110 of circulation for liquid on the baffle plate 11.Collecting chamber 102 is by cup inwall 12, and baffle plate 11 and cup opening 101 are formed.Comprise detectable bar 16 and the back up pad 17 that is used for fixing detectable bar 16 in the test chamber 103, wherein detectable bar 16 is used for detecting saliva sample and whether contains the drug abuse material.The inwall of lid 20 has screw thread 25, the outer wall 18 on cup 10 tops has the screw thread that matches with lid 20 inwalls, be in primary importance at lid 20, when just screw thread is mismatched the position, sample in the spongy top 23 still exists wherein, when lid 20 is in the second place, just screw thread cooperatively interacts when tightening, and the sample in the spongy top 23 is extruded.The top of test chamber 103 is 101 1 pores 15 of opening also, make in air pressure in the test chamber 103 and the collecting chamber 102 quite, so that the unobstructed of liquid flows.The bottom 13 of test chamber is groove 104 parts of test chamber, can accept sample, so that the detectable bar 16 in the test chamber 103 touches sample.Detectable bar 16 is vertically placed, and along test chamber 103 annular arrangements, its sample region of acceptance just is positioned at the groove 104 of test chamber, in addition, cup 10 bottoms 13 are the elements that can separate with cup 10, and the bottom 13 of cup has the projection 14 of an arc, when convenience sample entered test chamber 103 from collecting chamber 102, the guiding sample flow was to the groove 104 of test chamber.

The gathering element 26 of this diagnostic detection device 1 comprises handle 21, and spongy top 23 even lid 20 can be independent of packing outside the cup 10, also can place collecting chamber 102 unitizings.When using diagnostic detection device 1, collect the saliva sample of capacity with gathering element 26 earlier, the gathering element 26 of lid 20 of will ining succession then vertically is placed in the collecting chamber 102, tighten lid 20 along screw thread, at this moment, saliva sample in the spongy top 23 can enter test chamber 103 along the through hole in the baffle plate 11 110, and the sample region of acceptance of detectable bar 16 can contact start detection with the sample in the groove 104 of test chamber.

Embodiment 2

As shown in Figure 6 and Figure 7, as different from Example 1, the test chamber 103 of the diagnostic detection device 1 in the present embodiment is built-in with back up pad 17, and this back up pad 17 comprises draw-in groove 171 that can fixed test reagent strip 16 and is used to prevent the support column 170 of detectable bar bending.The bottom 13 of back up pad 17 and cup 10 and the sidewall 18 of cup 10 have been formed test chamber 103 jointly.Also there is a projection 14 in the bottom 13 of cup.The top of projection 14 is a baffle plate 11.Baffle plate 11, the right side 141 of sidewall and bottom of cup projection 14, the left side of the projection 142 common grooves 104 of forming test chamber.Support column 170 is parallel with detectable bar 16, and is common vertical with the bottom 13 of cup 10, and sample region of acceptance one end of detectable bar 16 is near support column.Detectable bar 16 is along inwall 12 annular arrangements of back up pad 17, and the bottom of detectable bar 16 is the sample region of acceptance, sample can be absorbed in the detectable bar 16 to detect.The lid 20 of diagnostic detection device 1 and the sidewall 18 on cup top can spiral cooperate, and when lid 20 was positioned at primary importance, when just not have to screw with cup 10, sample also was present in the spongy top 23; When lid 20 is positioned at the second place, just with cup 10 close-fitting the time, 11 extruding of spongy top 23 baffle plates, saliva sample flows in the groove 104 of test chamber 103 along baffle plate 11, start detection.

Embodiment 3

As shown in Figure 8, as different from Example 1, the diagnostic detection device in the present embodiment comprises cup 10 and lid 20.Lid 20 is connected with gathering element 26 buckles and can shirks.Cup 20 is formed for two layers of walls, comprises inwall 12 and outer wall 18.Wherein, collecting chamber 102 is formed in the bottom 13 of inwall 12 and cup.Test chamber 104 is formed in the outer wall 18 of cup and cup inwall 12 and bottom 13.The opening of collecting chamber up, the position that communicates between collecting chamber and the test chamber is in opening 101 both sides.When using this diagnostic detection device, equally, collect sample with gathering element 26 earlier, the spongy top 23 of gathering element 26 is full of after the sample, place the collecting chamber 102 of cup 10, extruding gathering element 26 makes saliva sample isolate and be stored in the bottom of collecting chamber 102 from spongy top 23.Remove gathering element 26, and will shirk from lid 20 with the gathering element 26 of handle 21 and spongy top 23.Then, add the sample pretreatment solution of capacity, cover tight lid, reverse the diagnostic detection device then, the saliva sample in the collecting chamber 102 is flow in the groove 104 of test chamber, thus start detection.

Claims

1. diagnostic detection device, comprise the cup of forming by opening, bottom and sidewall, cup comprises the test chamber that is used to accept the collecting chamber of gathering element and holds the detectable bar, wherein collecting chamber and test chamber fluid connection, it is characterized in that this diagnostic detection device also comprises and is used to the lid that seals the cup opening and link to each other with gathering element.

2. diagnostic detection device as claimed in claim 1 is characterized in that described collecting chamber comprises the baffle plate that is used to stop gathering element.

3. diagnostic detection device as claimed in claim 2 is characterized in that described baffle plate is projected on the bottom of cup.

4. diagnostic detection device as claimed in claim 3 is characterized in that described test chamber comprises the groove of accepting sample from collecting chamber, and described groove comprises the part bottom and the partial sidewall of cup.

5. diagnostic detection device as claimed in claim 3 is characterized in that described test chamber comprises the support component of fixed test reagent strip.

6. diagnostic detection device as claimed in claim 5 is characterized in that, described support component comprises the draw-in groove that holds the detectable bar and prevents the support column of detectable bar bending.

7. diagnostic detection device as claimed in claim 6 is characterized in that, described detectable bar comprises the sample region of acceptance, and sample region of acceptance one end of detectable bar is near support column.

8. diagnostic detection device as claimed in claim 2 is characterized in that the sidewall of described cup comprises inner and outer wall, and the inwall of cup and opening and described baffle plate are formed described collecting chamber.

9. diagnostic detection device as claimed in claim 8 is characterized in that, has the through hole of circulation for liquid on the described baffle plate.

10. diagnostic detection device as claimed in claim 9 is characterized in that, bottom of cup comprises that also a guiding liquids flows to the projection of described test chamber.

11. diagnostic detection device as claimed in claim 2 is characterized in that, the bottom of described cup is removable lining element.

12., it is characterized in that being shaped as of described cup is cylindric as the described diagnostic detection device of one of claim 1 to 11.

13., it is characterized in that described detectable bar is positioned at cup and arranges in the form of a ring as the described diagnostic detection device of one of claim 1 to 11.

14., it is characterized in that described gathering element comprises the absorption region of fluid as the described diagnostic detection device of one of claim 1 to 11.

15., it is characterized in that described gathering element comprises spongy top that absorbs liquid and the handle that is connected with described lid as the described diagnostic detection device of one of claim 1 to 11.

16., it is characterized in that the open-top screw thread sealing of described lid and cup as the described diagnostic detection device of one of claim 1 to 11.

17. diagnostic detection device as claimed in claim 1 is characterized in that, described test chamber comprises an obstruction ring that stops sample to surpass the highest scale on the detectable bar.

18. diagnostic detection device as claimed in claim 17 is characterized in that the material of described obstruction ring comprises filter paper.