CN102657819B - Drug combination for treating dysthymic disorder - Google Patents
Drug combination for treating dysthymic disorder Download PDFInfo
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- CN102657819B CN102657819B CN 201210150147 CN201210150147A CN102657819B CN 102657819 B CN102657819 B CN 102657819B CN 201210150147 CN201210150147 CN 201210150147 CN 201210150147 A CN201210150147 A CN 201210150147A CN 102657819 B CN102657819 B CN 102657819B
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Abstract
The invention relates to a drug combination for treating dysthymic disorder.. The drug combination is prepared by uncaria, Chinese magnoliavine fruit, barbary wolfberry fruit, radix curcumae, cortex albiziae, caltrop, poria cocos, spina date seed, white paeony root, gardenia, acorus gramineus, rhizoma paridis, rhizoma gastrodiae, medofenoxate and costus root. The drug combination for treating the dysthymic disorder, disclosed by the invention, has the advantages of simpleness in component, easiness in obtaining the component, significant curative effect and no obvious side effect.
Description
Technical field
The present invention relates to the psychosis prevention field, particularly, the present invention relates to a kind of pharmaceutical composition for the treatment of dysthymia.
Background technology
Dysthymia is class spirit excited and mental tired, normal the be in a bad mood neurosis disorder of worry and psychological physiological signs easily easily.Have 25% to be the dysthymia patient in the patients with depression that is in hospital undergoing treatment.Except the symptom of general depression, dysthymia also has the characteristics of oneself, as the hallucination illusion.
Clinical treatment is many based on Western medicine at present, but its side effect is bigger, and dependency is strong, has brought more hidden danger in for patient treatment.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of dysthymia.
In order to realize purpose of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of dysthymia, it is characterized in that it is the medicament of being made according to weight proportion by following ingredients:
Preferably, the pharmaceutical composition for the treatment of dysthymia of the present invention is the medicament of being made according to weight proportion by following ingredients:
The pharmaceutical composition for the treatment of dysthymia of the present invention can be made various dosage forms according to technological means well-known to those skilled in the art, for example tablet (dispersible tablet), capsule, hard capsule, decoction etc.
The drug regimen composition formula for the treatment of dysthymia of the present invention is reasonable, and composition is simple and easy to, and is evident in efficacy, and do not have significant side effects.
The specific embodiment
The following examples will give further instruction to the present invention, but not thereby limiting the invention.
The preparation of embodiment 1 tablet
Hook taking rattan 500 grams, Fructus Schisandrae Chinensis 300 grams, Fructus Lycii 2000 grams, Radix Curcumae 500 grams, Cortex Albiziae 2000 grams, Fructus Tribuli 500 grams, Poria 300 grams, Semen Ziziphi Spinosae 1000 grams, the Radix Paeoniae Alba 1500 grams, Fructus Gardeniae 300 grams, Rhizoma Acori Graminei 1500 grams, Rhizoma Paridis 300 grams, Rhizoma Gastrodiae 1000 grams, Radix Et Caulis Acanthopanacis Senticosi 300 grams, the Radix Aucklandiae 300 grams, pulverizer is pulverized, cross 80 mesh sieves, add microcrystalline Cellulose 3000 grams, mannitol 1000 grams, mix homogeneously, amidin pelletize with 10 weight %, dry back and crospolyvinylpyrrolidone 500 gram mix homogeneously are pressed 1000.
Experimental example
Diagnostic criteria
" International Classification of Diseases-Di ten editions " that announces according to WHO and APA,American Psychiatric Association " mental disorder Diagnostic Statistical Manual-Di four editions " and the classification of Chinese mental disorder are diagnosed dysthymia with the diagnostic criteria third edition (CCMD-3) about the diagnostic criteria of depression, and the eliminating organic disease.Depressed degree wherein＜8 is divided into normally according to Hamilton depressive scale (HAMD) scoring (24) totally, and 8～18 are divided into slight depression, and 18～24 are divided into the moderate depression, and＞24 are divided into severe depression.The HAMD scoring is referring to " psychiatric department evaluation scale " [M]. Changsha: Hunan science and technology publishing house, 1993, the 122～203 pages.
Choose patient's 60 examples that meet above-mentioned standard, male 30 examples wherein, women 30 examples; 29～57 years old age, average 41 years old.
Use the tablet that makes among the embodiment 1 to treat, wherein one day 3 times, each a slice, treating January is a course for the treatment of.
Criterion of therapeutical effect
HAMD scoring before and after the record treatment respectively.Being clinical recovery to subtract branch rate 〉=75%, is marked improvement to subtract branch rate 〉=50%, is progress to subtract branch rate 〉=30%, is invalid with＜30%.
Through the observation of a course for the treatment of, find that whole patients all meet the standard of clinical recovery, and during whole treatment, do not observe tangible untoward reaction.
Claims (1)
1. a pharmaceutical composition for the treatment of dysthymia is characterized in that, it is the medicament of being made according to weight proportion by following ingredients:
Ramulus Uncariae Cum Uncis 5 weight portion Fructus Schisandrae Chinensis 3 weight portion Fructus Lycii 20 weight portions
Radix Curcumae 5 weight portion Cortex Albiziaes 20 weight portion Fructus Tribulis 5 weight portions
The Poria 3 weight portion Semen Ziziphi Spinosaes 10 weight portion Radix Paeoniae Albas 15 weight portions
Fructus Gardeniae 3 weight portion Rhizoma Acori Graminei 15 weight portion Rhizoma Paridis 3 weight portions
The Rhizoma Gastrodiae 10 weight portion Radix Et Caulis Acanthopanacis Senticosis 3 weight portion Radix Aucklandiae 3 weight portions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210150147 CN102657819B (en) | 2012-05-16 | 2012-05-16 | Drug combination for treating dysthymic disorder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210150147 CN102657819B (en) | 2012-05-16 | 2012-05-16 | Drug combination for treating dysthymic disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657819A CN102657819A (en) | 2012-09-12 |
| CN102657819B true CN102657819B (en) | 2013-07-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201210150147 Active CN102657819B (en) | 2012-05-16 | 2012-05-16 | Drug combination for treating dysthymic disorder |
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| CN (1) | CN102657819B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836324B (en) * | 2012-09-20 | 2013-11-13 | 李龙飞 | Decoction for treating schizophrenia |
| CN105561141A (en) * | 2014-10-13 | 2016-05-11 | 黄名玉 | Medicine for treating depression |
| CN104383441A (en) * | 2014-11-12 | 2015-03-04 | 刘淑兰 | Method for preparing Chinese patent medicine for treating postpartum depression |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1830458A (en) * | 2005-03-11 | 2006-09-13 | 上海医药工业研究院 | New use of tribulus terrestris extraction |
| CN101168024A (en) * | 2007-10-25 | 2008-04-30 | 陈卫辉 | Proprietary Chinese medicine for treating depression and production method thereof |
| CN101496889A (en) * | 2008-01-28 | 2009-08-05 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for tranquilizing mind, quieting spirit, soothing liver and relieving depression, and preparation method thereof |
| CN101502608A (en) * | 2008-02-04 | 2009-08-12 | 北京凯瑞创新医药科技有限公司 | Chinese paris rhizome total sapogenin oral medication preparation as well as preparation method and application thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH048481A (en) * | 1990-04-27 | 1992-01-13 | Mitsutomo:Kk | Coupler |
| JPH09208481A (en) * | 1996-02-05 | 1997-08-12 | Hagino Nobuyoshi | Psychotropic composition |
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2012
- 2012-05-16 CN CN 201210150147 patent/CN102657819B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1830458A (en) * | 2005-03-11 | 2006-09-13 | 上海医药工业研究院 | New use of tribulus terrestris extraction |
| CN101168024A (en) * | 2007-10-25 | 2008-04-30 | 陈卫辉 | Proprietary Chinese medicine for treating depression and production method thereof |
| CN101496889A (en) * | 2008-01-28 | 2009-08-05 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for tranquilizing mind, quieting spirit, soothing liver and relieving depression, and preparation method thereof |
| CN101502608A (en) * | 2008-02-04 | 2009-08-12 | 北京凯瑞创新医药科技有限公司 | Chinese paris rhizome total sapogenin oral medication preparation as well as preparation method and application thereof |
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| CN102657819A (en) | 2012-09-12 |
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Owner name: LIYANG SHANGHUANG HOSPITALS Free format text: FORMER OWNER: GAO XINHUA Effective date: 20131126 |
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Free format text: CORRECT: ADDRESS; FROM: 272051 JINING, SHANDONG PROVINCE TO: 213314 CHANGZHOU, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20131126 Address after: 213314, Huang Zhen Town, Liyang, Jiangsu, Changzhou Patentee after: Liyang Huang Zhen Town Health Center Address before: 272051 Shandong province Jining city wear Zhuangji wearing No. 1 Shandong Road, Jining city mental hospital Patentee before: Gao Xinhua |