CN102836324B - Decoction for treating schizophrenia - Google Patents

Decoction for treating schizophrenia Download PDF

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Publication number
CN102836324B
CN102836324B CN2012103504491A CN201210350449A CN102836324B CN 102836324 B CN102836324 B CN 102836324B CN 2012103504491 A CN2012103504491 A CN 2012103504491A CN 201210350449 A CN201210350449 A CN 201210350449A CN 102836324 B CN102836324 B CN 102836324B
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parts
radix
decoction
rhizoma
grams
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CN102836324A (en
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李龙飞
张焕君
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Abstract

The invention relates to decoction for treating schizophrenia. The decoction is prepared from the following materials in parts by weight: 3 parts of liquorice, 2 parts of radix asparagi, 3 parts of glossy privet fruit, 2 parts of costustoot, 5 parts of fructus schisandrae, 2 parts of rhizoma cimicifugae, 4 parts of radix morindae officinalis, 2 parts of cortex eucommiae, 4 parts of nightshade, 3 parts of seville orange flower, 2 parts of white atractylodes rhizome, 6 parts of radix clematidis, 10 parts of gansui root, 2 parts of white paeony root, 8 parts of albizia flower and 10 parts of rhizoma acori graminei. The decoction is convenient to take orally, has obvious effect and is suitable for large-scale clinical popularization.

Description

A kind ofly treat schizoid decoction
Technical field
The present invention relates to the psychosis prevention field, relate in particular to a kind of decoction for the treatment of schizophrenia.
Background technology
Schizophrenia is a kind of mental sickness that the cause of disease it be unclear that, and a lot of diseases are in person between twenty and fifty, and onset is slow, and the many protracteds course of disease of patient's natural history, be and repeatedly increase the weight of or worsen.At present, treat clinically schizophrenia medicine loxapine class commonly used, the not ideal and easy recurrence of curative effect, side effect is also very large.
Summary of the invention
The purpose of this invention is to provide a kind of decoction for the treatment of schizophrenia.
In order to realize purpose of the present invention, the invention provides a kind of schizoid decoction for the treatment of, it is to be made by the material of following weight proportioning: 10 parts of 3 parts, Radix Glycyrrhizae, 2 parts of Radix Asparagis, 3 parts of Fructus Ligustri Lucidi, 2 parts of the Radix Aucklandiae, 5 parts of Fructus Schisandrae Chinensis, 2 parts of Rhizoma Cimicifugaes, 4 parts of Radix Morindae Officinaliss, 2 parts of the Cortexs Eucommiae, 4 parts of Herba Solani Nigris, 3 parts of CitrusaurantiumL.Var.amara Engl.s, 2 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Radix Clematidis, 10 parts of Radix Kansuis, 2 parts of the Radix Paeoniae Albas, 8 parts of Flos Albiziaes and Rhizoma Acori Graminei.
The schizoid decoction convenient oral for the treatment of of the present invention, effect is remarkable, is suitable for large-scale promotion clinically.
The specific embodiment
Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for explanation the present invention rather than limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Except as otherwise noted, otherwise the percent in the present invention is percetage by weight.
Embodiment 1
Take Radix Glycyrrhizae 30 grams, Radix Asparagi 20 grams, Fructus Ligustri Lucidi 30 grams, the Radix Aucklandiae 20 grams, Fructus Schisandrae Chinensis 50 grams, Rhizoma Cimicifugae 20 grams, Radix Morindae Officinalis 40 grams, the Cortex Eucommiae 20 grams, Herba Solani Nigri 40 grams, CitrusaurantiumL.Var.amara Engl. 30 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Radix Clematidis 60 grams, Radix Kansui 100 grams, the Radix Paeoniae Alba 20 grams, Flos Albiziae 80 grams and Rhizoma Acori Graminei 100 grams, add 1000 milliliters, water, depressed reflux 3 hours at 1 standard atmosphere, be cooled to 25 ℃, filter, collect filtrate and namely obtain decoction of the present invention.
Experimental example
Schizophrenic's 65 examples that selection is made a definite diagnosis are as treatment group, wherein the patient all meets " Chinese Spirit classification of diseases and diagnostic criteria (third edition) " schizoid diagnostic criteria, the positive and scale for the assessment of negative symptoms (PANSS) scoring be not less than 60 minutes (psychiatric department branch of Chinese Medical Association. Chinese Spirit Obstacles classification and diagnostic criteria (third edition) [M]. Jinan: Shandong science tech publishing house, 2002:75.).Get rid of the patient with physical diseases such as severe cardiac, liver and kidneys, get rid of ethanol or drug dependence patient, disturbance of intelligence person and just using other antischizophrinic things person.Male 39 examples wherein, female's 26 examples; 19~59 years old age, average 32.1 years old.
Prepare decoction in use embodiment 1 and treat, three times on the one, each 50 milliliters, treated continuously for 10 weeks.
Curative effect determinate standard
Adopt the positive and scale for the assessment of negative symptoms (PANSS), untoward reaction scale (TESS) evaluation curative effect and untoward reaction, respectively evaluated 1 time in 2,4,8,10 weeks before treatment and after treatment.Take PANSS subtract minute rate greater than 75% as curing; Subtract minute rate and be marked improvement greater than 50%; Subtract minute rate and be progress greater than 25%; Subtract minute rate less than 25% for failing to respond to any medical treatment.Healing, marked improvement, progressive always adding up to effectively.
Result
Therapeutic outcome sees the following form.
PANSS scoring before and after table 1 patient treatment (n=65,
Figure BSA00000780243000031
)
Figure BSA00000780243000032
Table 2 patient clinical curative effect [example (%)]
TESS scoring after table 3 patient treatment
Figure BSA00000780243000034
Figure BSA00000780243000035
In therapeutic process, the less appearance of adverse effect.

Claims (1)

1. treat schizoid decoction for one kind, it is characterized in that, it is to be made by the material of following weight proportioning: 10 parts of 3 parts, Radix Glycyrrhizae, 2 parts of Radix Asparagis, 3 parts of Fructus Ligustri Lucidi, 2 parts of the Radix Aucklandiae, 5 parts of Fructus Schisandrae Chinensis, 2 parts of Rhizoma Cimicifugaes, 4 parts of Radix Morindae Officinaliss, 2 parts of the Cortexs Eucommiae, 4 parts of Herba Solani Nigris, 3 parts of CitrusaurantiumL.Var.amara Engl.s, 2 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Radix Clematidis, 10 parts of Radix Kansuis, 2 parts of the Radix Paeoniae Albas, 8 parts of Flos Albiziaes and Rhizoma Acori Graminei.
CN2012103504491A 2012-09-20 2012-09-20 Decoction for treating schizophrenia Expired - Fee Related CN102836324B (en)

Priority Applications (1)

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CN102836324B true CN102836324B (en) 2013-11-13

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10383910B2 (en) 2016-04-27 2019-08-20 King Abdulaziz University Methods of increasing fertility of a male subject with costus speciosus extract

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101579511A (en) * 2009-07-02 2009-11-18 陈雪梅 Drug combination used for treating schizophrenia
CN102078559A (en) * 2009-12-01 2011-06-01 王小华 Chinese medicinal composition with functions of tonifying kidney and strengthening brain
CN102319406A (en) * 2011-10-10 2012-01-18 张运林 Medicament for treating tristimania
CN102657819A (en) * 2012-05-16 2012-09-12 高新华 Drug combination for treating dysthymic disorder

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101579511A (en) * 2009-07-02 2009-11-18 陈雪梅 Drug combination used for treating schizophrenia
CN102078559A (en) * 2009-12-01 2011-06-01 王小华 Chinese medicinal composition with functions of tonifying kidney and strengthening brain
CN102319406A (en) * 2011-10-10 2012-01-18 张运林 Medicament for treating tristimania
CN102657819A (en) * 2012-05-16 2012-09-12 高新华 Drug combination for treating dysthymic disorder

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