CN102698053B - Nacre Chinese herbal preparation for relieving depression and preparation method of same - Google Patents
Nacre Chinese herbal preparation for relieving depression and preparation method of same Download PDFInfo
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- CN102698053B CN102698053B CN2012102089839A CN201210208983A CN102698053B CN 102698053 B CN102698053 B CN 102698053B CN 2012102089839 A CN2012102089839 A CN 2012102089839A CN 201210208983 A CN201210208983 A CN 201210208983A CN 102698053 B CN102698053 B CN 102698053B
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Abstract
The invention discloses a nacre Chinese herbal preparation for relieving depression, which is prepared by the following traditional Chinese medicine raw materials according to weight portion: 200 to 400 portions of nacre, 100 to 300 portions of tuber fleeceflower stem, 40 to 200 portions of white paeony root, 40 to 200 portions of dogberry-tree, 40 to 200 portions of cortex albiziae, 50 to 250 portions of asparagus, and 50 to 250 portions of lily, and all the medicines have the effects of nourishing yin, reducing fever, and calming the nerves, the Chinese herbal preparation provided by the invention has an obvious curative effect to fire excess from yin deficiency type depression patients, can rapidly relieve the symptoms of dizziness, cardiopalmus, less sleep, upsetting and crossness, or spermatorrhea and soreness of waist, and the preparation provided by the invention is nontoxic and has no side effect, has an obvious curative effect, and can relieve the pain of patients fundamentally.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation of Concha Margaritifera for alleviate depression disease and preparation method.
Background technology
Depression be a kind of take depressed, slowness of thinking and speech action reduce, the slow will of feelings as main feature obstacle mental disease.A people is depressed more than continuing for two weeks, can't regulate voluntarily, just can be considered the pathological depression state.If lasting 1～3 month depressed, no matter which kind of reason all can be considered depression.Depression belongs to the traditional Chinese medical science " melancholia " category, belongs to YIN syndrome, relates to the heart, lung, liver,spleen,kidney.Main manifestations for feeling depressed, distending pain over the hypochondrium or irritability is kind cries and the various complicated symptoms such as insomnia.Depressed main pathogenesis is because feelings will is hindered, due to depression of liver-QI causes that gradually the five internal organs mechanism of qi gets along well.But be mainly liver, spleen, the heart is got involved and disorder of QI and blood forms.The traditional Chinese medical science is thought the generation of melancholia because of the institute of disgruntled, grieved, worried seven emotions wound in a word, causes that the liver failing to maintain the normal flow of QI, spleen lose transporting, the internal organs yin and yang qi and blood disorder forms.The just cause of disease stagnation of QI and hold damp-phlegm, food stagnation, heat stagnation person under the arm, how true card; Prolonged illness is by gas and blood, and Sthenia is transforming into asthenia, as for a long time strongly fragrant, overtaxes one's nerves, and hyperactivity of fire caused by deficiency of YIN etc. all belong to deficiency syndrome.Emotional disorder is the not normal a kind of external reaction of function, with the closely-related internal organs of feelings will be the heart, liver, spleen, wherein, the effect of taste is more outstanding." here gods go out for heart person, the viscus likened to the monarch in the body " is the main internal organs that carry out thinking activities.Liver controlling conveyance and dispersion, harmonizing emotions, play an important role to keeping happy.Taste, as the foundation of acquired constitution, are brought into play its regulation of mental activities function by many-side.On physiology, spleen is source of generating QI and blood, is the material base of feelings will activity; Be the pivot of rising and falling of QI again, and then affect the normal operation of body fluid; Moreover The spleen and the stomach are interior-exteriorly related, by large stomach collateral and the heart, gets in touch with communication, thereby affect the function of heart storing spirit." the meteorological opinion of Plain Questions normal person " cloud: " large stomach collateral, life is said in void, passes through diaphragm network lung, under left breast." on pathology, " anxiety making QI depressed ", stagnation of QI causing fluid-retention, damp contamination, and spleen preferring dryness to dampness, dysfunction of the spleen in transportation, water Tianjin cloth not, poly-and give birth to expectorant.Zhang Congzheng " Confucian's Duties to Their Parents " cloud: " the spleen master thinks, and thinks for a long time endlessly spleen knot, therefore be also prolonged fluid-retention." expectorant is evil causes a disease extensively, therefore saying of " strange illness is expectorant all " arranged, stagnation of phlegm converting into fire, hoodwink the mind, on disturb key clearly, can show as abnormal mind.In general the process of western medical treatment depression is exactly for its symptom treatment, adopts antidepressants or calm class Western medicine to carry out mitigate the disease.On the whole, western medical treatment depression advantage is that therapeutic effect is obvious, instant effect, but also exist huge shortcoming simultaneously, because the western medical treatment depression has been ignored the treatment of depression cause of disease old complaint just for disease, make treatment only rest on surface, can not tackle the problem at its root.Simultaneously, the life-time service of Western medicine makes toxic and side effects large, and easily recurrence, produce drug resistance, and these are all that Western medicine is unavoidable.Adopt the means of Chinese medicine to carry out Cure of depression, giving consideration to both the incidental and fundamental, be a channel extremely leaved for development, and applied widely, there is its original effect the treatment aspect.
Summary of the invention
Purpose of the present invention is exactly in order to overcome the above-mentioned defect of prior art, and a kind of advantages of perfect compatibility that has is provided, have no side effect, and Concha Margaritifera Chinese medicine preparation and the preparation method of the reliable alleviate depression disease of curative effect.
For achieving the above object, the present invention is achieved by the following technical solutions:
The Concha Margaritifera Chinese medicine preparation of alleviate depression disease, made by the raw material of Chinese medicine of following weight portion:
Concha Margaritifera 200-400 part, Caulis Polygoni Multiflori 100-300 part, Radix Paeoniae Alba 40-200 part, Fructus Corni 40-200 part, Cortex Albiziae 40-200 part, Radix Asparagi 50-250 part, Bulbus Lilii 50-250 part.
The Concha Margaritifera Chinese medicine preparation of described alleviate depression disease, made by the raw material of Chinese medicine of following weight portion:
300 parts of Concha Margaritiferas, 200 parts of Caulis Polygoni Multiflori, 120 parts of the Radix Paeoniae Albas, 120 parts of Fructus Corni, 120 parts of Cortex Albiziaes, 150 parts of Radix Asparagis, 150 parts of Bulbus Liliies.
The preparation method of the Concha Margaritifera Chinese medicine preparation of described alleviate depression disease, its preparation method is:
get the raw material of Chinese medicine Concha Margaritifera powder and be broken into 40 order fine powders, take in proportion 300 parts of raw material of Chinese medicine Concha Margaritiferas, 200 parts of Caulis Polygoni Multiflori, 120 parts of the Radix Paeoniae Albas, 120 parts of Fructus Corni, 120 parts of Cortex Albiziaes, 150 parts of Radix Asparagis, 150 parts of Bulbus Liliies, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, the water that adds for the first time 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filter, the water that adds for the second time 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, after meal half an hour, 4 weeks were 1 course for the treatment of.
The pharmacological action of crude drug of the present invention is as follows, Concha Margaritifera: salty, cold, return liver, heart channel, suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving; Caulis Polygoni Multiflori: sweet, flat, enter the heart, Liver Channel, tranquilizing by nourishing the heart; The Radix Paeoniae Alba: bitter, acid, be slightly cold, return liver, spleen channel, the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG; Fructus Corni: acid, tepor, return liver, kidney channel, liver and kidney tonifying, the convergence astringent or styptic treatment for spontaneous sweating; Cortex Albiziae: sweet, flat, GUIXIN, Liver Channel, the resolving depression of calming the nerves, promoting blood circulation and detumescence; Radix Asparagi: sweet, bitter, Great Cold, return lung, kidney channel, lung heat clearing pathogenic fire reducing, nourshing Yin and drynsessmoistening prescription; Bulbus Lilii: sweet, cold, return lung, heart channel, nourishing YIN and moistening the lung cough-relieving, clearing away heart-fire for tranquillization; All medicines are played the merit that nourishing YIN and clearing away heat is calmed the nerves altogether, Chinese medicine preparation of the present invention has remarkable therapeutic effect to the type of hyperactivity of fire caused by deficiency of YIN patients with depression, can alleviate rapidly dizzy, cardiopalmus, sleep less, susceptible to lose temper due to restlessness, or the symptom of the seminal emission soreness of waist, this preparation has no side effect, and therapeutic effect is remarkable, has fundamentally removed patient's misery.
The specific embodiment
EXAMPLE l:
Raw material of Chinese medicine: 300 parts of Concha Margaritiferas, 200 parts of Caulis Polygoni Multiflori, 120 parts of the Radix Paeoniae Albas, 120 parts of Fructus Corni, 120 parts of Cortex Albiziaes, 150 parts of Radix Asparagis, 150 parts of Bulbus Liliies.
preparation method: get the raw material of Chinese medicine Concha Margaritifera powder and be broken into 40 order fine powders, take in proportion 300 parts of raw material of Chinese medicine Concha Margaritiferas, 200 parts of Caulis Polygoni Multiflori, 120 parts of the Radix Paeoniae Albas, 120 parts of Fructus Corni, 120 parts of Cortex Albiziaes, 150 parts of Radix Asparagis, 150 parts of Bulbus Liliies, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, the water that adds for the first time 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filter, the water that adds for the second time 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 2
Raw material of Chinese medicine: 400 parts of Concha Margaritiferas, 300 parts of Caulis Polygoni Multiflori, 200 parts of the Radix Paeoniae Albas, 200 parts of Fructus Corni, 200 parts of Cortex Albiziaes, 250 parts of Radix Asparagis, 250 parts of Bulbus Liliies.
preparation method: get the raw material of Chinese medicine Concha Margaritifera powder and be broken into 40 order fine powders, take in proportion 400 parts of raw material of Chinese medicine Concha Margaritiferas, 300 parts of Caulis Polygoni Multiflori, 200 parts of the Radix Paeoniae Albas, 200 parts of Fructus Corni, 200 parts of Cortex Albiziaes, 250 parts of Radix Asparagis, 250 parts of Bulbus Liliies, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, the water that adds for the first time 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filter, the water that adds for the second time 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 3:
Raw material of Chinese medicine: 200 parts of Concha Margaritiferas, 100 parts of Caulis Polygoni Multiflori, 40 parts of the Radix Paeoniae Albas, 40 parts of Fructus Corni, 40 parts of Cortex Albiziaes, 50 parts of Radix Asparagis, 50 parts of Bulbus Liliies.
preparation method: get the raw material of Chinese medicine Concha Margaritifera powder and be broken into 40 order fine powders, take in proportion 200 parts of raw material of Chinese medicine Concha Margaritiferas, 100 parts of Caulis Polygoni Multiflori, 40 parts of the Radix Paeoniae Albas, 40 parts of Fructus Corni, 40 parts of Cortex Albiziaes, 50 parts of Radix Asparagis, 50 parts of Bulbus Liliies, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, the water that adds for the first time 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filter, the water that adds for the second time 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 4:
Clinical trial
1) physical data:
Adopt Chinese medicine preparation of the present invention to treat altogether 27 routine patients, male 10 examples wherein, female's 17 examples; Age is 40-70 years old, average 55 years old, and medical history 1-7.
2) diagnostic criteria: primary symptom: dizzy, cardiopalmus, sleep less, susceptible to lose temper due to restlessness, or the seminal emission soreness of waist.The few tongue of red tongue, stringy,thready and rapid pulse.
3) Therapeutic Method: the oral embodiment of the present invention 1 Chinese medicine decoction, each 180ml, every day 2 times, after meal half an hour, 4 weeks were 1 course for the treatment of, evaluated therapeutic outcome 3 courses for the treatment of.
4) the standard of curative effect evaluation:
Recovery from illness: above-mentioned primary symptom disappears;
Produce effects: above-mentioned primary symptom disappears substantially;
Effectively: above-mentioned primary symptom is improved;
Invalid: above-mentioned primary symptom is without obvious improvement.
5) therapeutic outcome: 27 3 of routine patients result course for the treatment of recovery from illness, 20 examples, produce effects 4 examples, effective 3 examples, invalid 0 example, total effective rate 100%.
Embodiment 5:
Model case: history, 44 years old, the female, dizzy, cardiopalmus, sleep less, susceptible to lose temper due to restlessness, the few tongue of red tongue, stringy,thready and rapid pulse, the Chinese medicine preparation of taking embodiment 1 takes effect 1 course for the treatment of, 3 recoveries from illness courses for the treatment of.
Embodiment 6:
Model case: Tan, 55 years old, the man, dizzy, cardiopalmus, sleep less, susceptible to lose temper due to restlessness, the soreness of waist, the few tongue of red tongue, stringy,thready and rapid pulse, the Chinese medicine preparation of taking embodiment 1 takes effect 1 course for the treatment of, 3 recoveries from illness courses for the treatment of.
Claims (2)
1. the Concha Margaritifera Chinese medicine preparation of alleviate depression disease, it is characterized in that: the raw material of Chinese medicine by following weight portion is made:
Concha Margaritifera 200-400 part, Caulis Polygoni Multiflori 100-300 part, Radix Paeoniae Alba 40-200 part, Fructus Corni 40-200 part, Cortex Albiziae 40-200 part, Radix Asparagi 50-250 part, Bulbus Lilii 50-250 part.
2. the Concha Margaritifera Chinese medicine preparation of alleviate depression disease described according to claim l, it is characterized in that: the raw material of Chinese medicine by following weight portion is made:
300 parts of Concha Margaritiferas, 200 parts of Caulis Polygoni Multiflori, 120 parts of the Radix Paeoniae Albas, 120 parts of Fructus Corni, 120 parts of Cortex Albiziaes, 150 parts of Radix Asparagis, 150 parts of Bulbus Liliies.
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| CN103720791B (en) * | 2013-12-19 | 2015-11-18 | 王晓源 | A kind of strong medicine preventing and treating post-stroke depression and preparation method thereof |
| CN104606558A (en) * | 2015-02-13 | 2015-05-13 | 臧海阳 | Traditional Chinese medicine composition for treating yin-deficiency and fire-hyperactivity type depression |
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| CN101121016A (en) * | 2006-08-09 | 2008-02-13 | 厦门桂龙投资管理有限公司 | Traditional Chinese medicine composition for treating neurasthenia and its preparation method |
| CN101658627A (en) * | 2009-08-10 | 2010-03-03 | 黄山 | Granules for tranquillization |
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| CN101121016A (en) * | 2006-08-09 | 2008-02-13 | 厦门桂龙投资管理有限公司 | Traditional Chinese medicine composition for treating neurasthenia and its preparation method |
| CN101658627A (en) * | 2009-08-10 | 2010-03-03 | 黄山 | Granules for tranquillization |
Non-Patent Citations (2)
| Title |
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| 朱丹溪心身医学思想初探;黄健等;《山西中医》;20070630;第23卷(第3期);第1-2页 * |
| 黄健等.朱丹溪心身医学思想初探.《山西中医》.2007,第23卷(第3期),第1-2页. |
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Effective date of registration: 20140627 Address after: 226100 Jiangsu city of Nantong Province Haimen town Sijia bridge village head sixteen Group No. 16 Patentee after: Jiang Xixiong Address before: 523120, 702, room 1, Peony Pavilion, Dongcheng business garden, Dongguan, Guangdong, Dongcheng District Patentee before: Chen Huiting |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131113 |
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| CF01 | Termination of patent right due to non-payment of annual fee |