CN101474373B - Chinese medicine for treating acute pharyngitis - Google Patents
Chinese medicine for treating acute pharyngitis Download PDFInfo
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Abstract
The invention relates to a Chinese medicine for the treatment of acute pharyngitis, which can effectively overcome the problems of poor medicinal effect and the acute pharyngitis treatment, the method thereof comprises the steps as follows: preparing by raw materials such as 140-160g of perilla leaf, 110-130g of mint, 200-240g of dark plum, 65-85g of Chinese white olive, 65-85g of root of kudzu vine, 65-85g of reed rhizome, 65-85g of balloon flower, 35-45g of licorice, 18-22g of borax, 0.18-0.22g of borneol, 365-445g of sucrose and 49-59g of dextrin; adding water into the wumei, perilla leaf,Chinese white olive, reed rhizome, mint, root of kudzu vine, balloon flower and licorice followed by extraction of volatile oils; using the distilled aqueous solution as a backup; adding the water into dregs for being decocted three times; combining and filtering the decoction to be combined with the distilled aqueous solution followed by reduced pressure concentration; adding alcohol, centrifugally removing precipitate, filtering the supernatant fluid, and decompressing the filtrate to recover the alcohol for being concentrated; adding the sucrose and the dextrin to prepare granules for being dried; adding borax for being mixed uniformly and dried with the alcohol-dissolved borneol and the volatile oils; and preparing tablets. The invention has excellent therapeutic effect, convenient medicine use and enormous economic and social benefits.
Description
One, technical field
The present invention relates to field of medicaments, particularly a kind of Chinese medicine for the treatment of acute pharyngitis (claim again Su Mei feel well buccal tablet).
Two, technical background
Acute pharyngitis is one of common clinical, and throat occupy on the lung stomach, is the door of lung stomach, the following speech of throat the five internal organs are the moon of brothers, the following speech of throat six internal organs, be brothers' sun, so the throat planted agent vital organs of the human body, pharynx person swallow also, main water flowing paddy, for stomach is to reach the passage of gastric qi, larynx person sky also, main breath is the passage of lung, six gas in the external world are invariably about this, and gas and his like works in the five internal organs, water paddy take the photograph Na Da in six internal organs, the whole body of the old friend only ground of throat is the most critical, if internal organs enrich, the lung stomach is gentle, and the not well-behaved then health of six gas is safe and sound, one has wind heat to attack outward, evil poison accumulates long-pending, interior transmission from one channel to another network, airsetting stasis, the internal resistance of the expectorant stasis of blood, evil poison follow through on burn, malicious intrinsic heat is tied in throat, then makes all diseases of throat all and send out.Particularly, the quickening with process of industrialization of improving constantly along with people's living standard, the variation of environmental aspect and tobacco and wine stimulation etc., the sickness rate of acute pharyngitis rises gradually in recent years, acute pharyngitis belongs to motherland's medical science " sore throat " more, " pharyngalgia ", the category of " pharyngeal swelling ", throat is the door of lung stomach, the interior logical vital organs of the human body, outward should natural six gas, so deficiency and excess cold and heat of the vital organs of the human body, having of nature six gas is too late, and the product of pungent stimulation are attacked the people, the chief criminal is in pharynx invariably, so the traditional Chinese medical science has saying of " ten people, nine pharyngopathies ", acute pharyngitis is attacked outward with wind heat clinically, exuberant lung-stomach heat for seeing more, the western medical treatment acute pharyngitis is many based on antibiotic, and the method for Chinese traditional treatment acute pharyngitis is more, on route of administration, how with oral, external is blown deposited, contains to turn to the master, and wherein external application dispels class, though onset is fast, but medication inconvenience is arranged, and the shortcoming that taste is not easy for patients to accept is though oral class is easy for patients to accept, but drug effect is difficult to play a role pharyngeal, onset is slower, and containing class acts on local rapid-action, though several dosage forms are arranged at present, but how to form with the product of heat-clearing and toxic substances removing, so the not good regret of flavour of a drug is arranged, more cold and cool because of these property of medicine, the rapid wear sun injures one's stomach, very the person has the cold fraud of icing volt of holding back, thereby limited its clinically extensive use and the breakthrough on the curative effect, therefore can develop a kind of good effect, and the Chinese medicine of easier treatment acute pharyngitis for extensive patients acceptance?
Three, summary of the invention
At above-mentioned situation, for overcoming the prior art defective, the present invention's purpose just provides a kind of Chinese medicine for the treatment of acute pharyngitis, can effectively overcome existing medicine medication inconvenience, taste is not easy for patients to accept, onset is slower, drug effect is not good, thereby solve effective treatment problem of acute pharyngitis, the technical scheme of its solution is, according to theory of Chinese medical science, acute pharyngitis belongs to " sore throat ", " pharyngalgia ", the category of " pharyngeal swelling ", gastric qi is unclear, clearly with sweet cold, lung qi is unclear, clearly with Liang Run, wind heat is attacked outward, the throat susceptible, scorching in the stagnated fire, it is thin that the product that sweet cold is moistened are feared its power, the kind person of controlling directly must lead evil in outside, in order to do heresy outlet is arranged, so Chinese medicine of the present invention adopts by Folium Perillae 140-160g, Herba Menthae 110-130g, Fructus Mume 200-240g, Fructus Canarii 65-85g, Radix Puerariae 65-85g, Rhizoma Phragmitis 65-85g, Radix Platycodonis 65-85g, Radix Glycyrrhizae 35-45g, Borax 18-22g, Borneolum Syntheticum 0.18-0.22g, sucrose 365-445g and dextrin 49-59g make as raw material, wherein, get the Fructus Mume of above-mentioned recipe quantity, Folium Perillae, Fructus Canarii, Rhizoma Phragmitis, Herba Menthae, Radix Puerariae, Radix Platycodonis and Radix Glycyrrhizae eight flavor medicines, the water that adds 15 times of weight of above-mentioned 8 herbal medicines, extract volatile oil with the steam distillation method, steam the aqueous solution device collection in addition after slipping, standby, the decocting that medicinal residues add medicinal residues 15-10 times weight boils three times, three decoction liquor are merged, filter, the aqueous solution after filtrate and above-mentioned steaming are slipped merges, and gets mixed liquor, being evaporated to 50 ℃ of following relative densities is 1.1, adding ethanol makes mixed liquor contain the alcohol amount to reach 20%, left standstill the centrifugal precipitation of removing 24 hours, supernatant filters, decompression filtrate recycling ethanol, and to be condensed into 50 ℃ of following relative densities be 1.4 extractum, adds sucrose and dextrin, make granule, drying is got the Borneolum Syntheticum dissolve with ethanol, and above-mentioned granule is added Borax, Borneolum Syntheticum after the dissolving and volatile oil, mixing, cold drying, compacting are in flakes.Prescription science of the present invention, therapeutic effect is good, taking convenience, compatibility is reasonable, and it is succeeded in developing, and is that one on the Chinese medicine is innovated greatly, and economic and social benefit is huge.
Four, the specific embodiment
Below in conjunction with practical situation the specific embodiment of the present invention is elaborated.
Provide by technical scheme, the present invention in the specific implementation, by Folium Perillae 140-160g, Herba Menthae 110-130g, Fructus Mume 200-240g, Fructus Canarii 65-85g, Radix Puerariae 65-85g, Rhizoma Phragmitis 65-85g, Radix Platycodonis 65-85g, Radix Glycyrrhizae 35-45g, Borax 18-22g, Borneolum Syntheticum 0.18-0.22g, sucrose 365-445g and dextrin 49-59g make as raw material, wherein, get the Fructus Mume of above-mentioned recipe quantity, Folium Perillae, Fructus Canarii, Rhizoma Phragmitis, Herba Menthae, Radix Puerariae, Radix Platycodonis and Radix Glycyrrhizae eight flavor medicines, the water that adds 15 times of weight of above-mentioned 8 herbal medicines, extract volatile oil with the steam distillation method, steam the aqueous solution device collection in addition after slipping, standby, medicinal residues decoct with water three times, the water that adds for the first time 15 times of amounts of medicinal residues gross weight, decocted 1.5 hours, the water that adds for the second time 10 times of amounts of medicinal residues gross weight, decocted 1 hour, the water that adds 10 times of amounts of medicinal residues gross weight for the third time, decocted 0.5 hour, three decoction liquor are merged, filter, aqueous solution after filtrate and above-mentioned steaming are slipped merges, and gets mixed liquor, and being evaporated to 50 ℃ of following relative densities is 1.1, add ethanol, make mixed liquor contain the alcohol amount and reach 20%, left standstill the centrifugal precipitation of removing 24 hours, supernatant filters, decompression filtrate recycling ethanol, and to be condensed into 50 ℃ of following relative densities be 1.4 extractum, adds sucrose and dextrin, make granule, drying is got the Borneolum Syntheticum dissolve with ethanol, and above-mentioned granule is added Borax, Borneolum Syntheticum after the dissolving and volatile oil, mixing, cold drying, compacting are in flakes.
Embodiment 1: by Folium Perillae 150g, Herba Menthae 120g, Fructus Mume 220g, Fructus Canarii 75g, Radix Puerariae 75g, Rhizoma Phragmitis 75g, Radix Platycodonis 75g, Radix Glycyrrhizae 40g, Borax 20g, Borneolum Syntheticum 0.2g, sucrose 405g and dextrin 54g make as raw material, get the Fructus Mume of above-mentioned recipe quantity, Folium Perillae, Fructus Canarii, Rhizoma Phragmitis, Herba Menthae, Radix Puerariae, Radix Platycodonis and Radix Glycyrrhizae eight flavor medicines, the water that adds 15 times of weight of above-mentioned 8 herbal medicines, extract volatile oil with the steam distillation method, steam the aqueous solution device collection in addition after slipping, standby, medicinal residues decoct with water three times, the water that adds for the first time 15 times of amounts of medicinal residues gross weight, decocted 1.5 hours, the water that adds for the second time 10 times of amounts of medicinal residues gross weight, decocted 1 hour, the water that adds 10 times of amounts of medicinal residues gross weight for the third time, decocted 0.5 hour, three decoction liquor are merged, filter, aqueous solution after filtrate and above-mentioned steaming are slipped merges, get mixed liquor, being evaporated to 50 ℃ of following relative densities is 1.1, add ethanol, make mixed liquor contain the alcohol amount and reach 20%, left standstill 24 hours, the centrifugal precipitation of removing, supernatant filters, decompression filtrate recycling ethanol, and be condensed into extractum 50 ℃ of following relative densities to 1.4, add sucrose and dextrin, make granule, drying is got the Borneolum Syntheticum dissolve with ethanol, above-mentioned granule is added Borax, Borneolum Syntheticum after the dissolving and volatile oil, mixing, cold drying, with pelleter be pressed into 1000, every heavy 0.6g.
In said medicine, wherein,
Folium Perillae: clean, dry, this product is the leaf of labiate wrinkle Folium Perillae, sharp Folium Perillae etc., the cold expelling that can induce sweat, relieving QI stagnancy in the stomach.
Herba Menthae: dry, the time spent drenches, and is vexed slightly, and cutting is dried, and dispelling wind and heat pathogens is arranged, the clear sharp head, the effect of rash sore-throat relieving.
Fructus Mume: dry, enucleation is pounded in the time spent moistening, astringes the lung, and astringing intestine to stop diarrhea promotes the production of body fluid, the effect of relieving colic caused by ascaris.
Fructus Canarii: claim Fructus Canarii albi again, clean, dry, lung heat clearing, sore-throat relieving promotes the production of body fluid, and laryngopharynx swelling and pain is controlled in detoxifcation, excessive thirst, cough is spitted blood, bacillary dysentery.
Radix Puerariae: rossing, to cut open, section is dried, and expelling pathogenic factors from muscles for reducing heat is arranged, and promoting the production of body fluid to quench thirst is sent out the effect of varioliform exanthema thoroughly.
Rhizoma Phragmitis: clean, moistening, cutting is dried, the effect that has clearing away heat and promoting production of body fluid to quench the thirst.
Radix Platycodonis: get root, clean, remove rough bark, shine soft straightening, dry, the dispersing and elevation lung qi is arranged, the effect of the evacuation of pus of eliminating the phlegm.
Radix Glycyrrhizae: clean and to remove earth, section is dried, invigorating the spleen and replenishing QI, and coordinating the actions of various ingredients in a prescription, heat-clearing and toxic substances removing is used for coordinating the actions of various ingredients in a prescription, makes it out of question, relaxes that it is high.
Borax: decontamination, industry is refined, the white crystal that congeals into give birth to or forge usefulness, external erosion prevention and muscle growing, the effect of interior usefulness heat clearing away clearing away phlegm.
Borneolum Syntheticum: levigation, causing resuscitation with aromatic drugs, the nebula of dispelling makes eye bright, and reducing swelling and alleviating pain cures mainly the coma convulsion and faints, various skin infection scabies of external curing and larynx disease, ophthalmic.
By above medicine as can be known, the Folium Perillae Herba Menthae, acrid in the mouth gas is clear, kind wind-dispelling heat-dissipating, its power can in saturating muscles and bones, reach the flesh table outward, the logical internal organs of a surname, run through meridians, kind treating the liver gas gallbladder fire stagnation knot is had a pain, laryngopharynx swelling and pain, the two mutually 5, the loose merit of heresy of dispelling wind is arranged; Fructus Mume, Fructus Canarii, sweet in the mouth and acid, sweet acid can be changed and gives birth to cloudy liquid, fill in the cloudy liquid, and then gastric heat gets and swallows supreme hardship of burning clearly, and it is respectful clearly that lung gets, the evil of the few fire of larynx inflammation; Radix Puerariae, Rhizoma Phragmitis are gone into lung, spleen, stomach warp, Gan Xin and putting down, kind stagnated fire and the expelling pathogenic factors from muscles heat of loosing, its gas is frivolous, can inspire gastric qi up, and its root is dark, can draw down that the water of the netherworld holds in last, play cloudy gas and relieving restlessness is quenched the thirst.More than four flavors, replenishing YIN and removing heat, Radix Platycodonis is arduous, can open the lung knot and eliminates the phlegm, and treats the pharynx detumescence and sound producing; Borneolum Syntheticum is arduous and cool, logical all keys, the stagnated fire of loosing, reducing swelling and alleviating pain.So beat a drum to swing the evil teacher that must rely guiding, Borax is sweet salty and cool, and Se Bai and body is light separates the expectorant heat of part of the body cavity above the diaphragm housing the heart and lungs chest and diaphragm, leads all medicines to reach on the chest and diaphragm, to the institute of pharynx, and wonderful in changing the decomposition poison, though that amount is lacked its meaning is also dark; The Radix Glycyrrhizae sweet in the mouth is flat, the old title of state is arranged, be intended to the lung moistening emergency, transfer all medicines and separate all poison, last four flavors are to make for assistant, full side is totally ten flavors, and its department is respectively arranged, the loose merit of heresy, heat-clearing and toxic substances removing, cleaning oral cavity, relieving sore throat to recover voice of the dispelling wind that gathers altogether, be effective to treat acute pharyngitis, and, obtained good result through clinical practice, its interrelated data is as follows:
One, selects the standard of case
The acute pharyngitis clinical manifestation is heating pharyngalgia, dryness and heat, dysphagia, mouthful little thirsty, halitosis, hoarseness and other pharynx, oral cavity portion discomfort, and therefore, all have an above symptom, all as the standard of selection case.
Two, diagnostic criteria
1, Western medicine diagnose standard
(1) medical history: often have suffer from cold, tired, tobacco and wine are excessive or the inducements such as stimulation of various physics and chemistry.
(2) symptom: onset is more anxious, pharyngeal drying, scorching hot, pain or odynophagia, heating, fear of cold, inappetence, extremities aching pain.
(3) check: pharyngeal mucosa hyperemia, color are scarlet, and pharynx rear wall lymph follicle and lateral pharyngeal band redness are local or have Huang, white secretions to adhere to, uvula, soft palate edema, and the sub-cultivation of pharynx examination can have pathogenic bacterium or feminine gender.
Possess above part or all of symptom, and inspection finding positive sign more than 1 or 1 is arranged, promptly diagnosable;
2, differential diagnosis in tcm
Wind heat disease: pharyngalgia, dryness and heat, dysphagia, mouthful little thirsty, heating, slight chill, pharyngeal red slightly or scarlet, edema, uvula redness, pharynx rear wall follicle hypertrophy, tongue tip side of red, white and thin fur or BOHUANG, floating and rapid pulse.
3, safety observation
(1) general health check-up project: temperature pulse respiration, blood pressure;
(2) blood, urine, just routine test;
(3) heart, liver, kidney function test;
4, health giving quality observation
(1) symptom: pharyngeal pain, odynophagia, dry pain, burning sensation or other senses of discomfort, heating and aversion to cold etc.
(2) pharyngeal sign: the degree of pharyngeal mucous membrane hyperemia, edema, pharyngeal and cervical region lymphoid tissue situation, uvula and soft palate edema situation.
(3) temperature taking.
(4) pharynx examination is cultivated.
More than (1), (2), (3) must do, other can be done according to the condition choosing.
5, observation procedure: adopt the single blind trial method, only the executor understands the grouping situation.
6, get rid of case standard (comprising incompatibility or rejecting standard)
(1) confirms on inspection by measles, scarlet fever, influenza, infectious monocytosis, causers such as agranulocytosis and leukemia.
(2) gestation or women breast-feeding their children are to this medicine allergy sufferers at under-18s or over-65s the age.
(3) be associated with serious primary disease person such as cardiovascular, liver, kidney and hemopoietic system, psychotic.
(4) do not meet the standard of including in, not medication in accordance with regulations can't be judged that curative effect or data are not congruent to affect the treatment or safety judgement person.
Three, therapeutic scheme
Oral Chinese medicine of the present invention every day 6 times, each 2, every 0.6g, 5 days is a course of treatment, the stop using medicine of other treatment pharyngitis of viewing duration, the state of an illness increases the weight of in 3 days, uses other medicines or other treatment measure instead, is considered as invalid case.
Four, curative effect determinate standard
3,5 days is a course of treatment, finishes back evaluation curative effect the course of treatment:
(1) clinical recovery: treat that various symptoms all disappear after 5 days;
(2) produce effects: treat 5 days symptom integral values and descend 〉=2/3;
(3) effective: as to treat after 5 days between the symptom integral value decline 2/3-1/3;
(4) invalid: as to treat the too late I/3 of symptom integral value decline after 5 days.
Five, statistical disposition
1, contrast according to the variation of every index before and after the medication and with matched group, utilize statistical method to judge that this medication imitates, pharyngitis 60 examples, and contrast with randomized and GUILIN XIGUA SHUANG buccal tablet, interrelated data is as follows:
Test group: containing Chinese medicine tablet of the present invention (grain), every day 6 times, each 2,5 days courses of treatment;
Matched group: containing Waterelon Frost Lozenges, every day 6 times, each 2, to produce by Guilin herbal pharmaceutical factory 5 days courses of treatment, authentication code: No. (1985) 1409, the accurate word of medicine, date of manufacture: 950420 are defended in osmanthus.
60 examples are observed in test altogether, and all patients divide it into test group and matched group by randomized, test group 40 examples wherein, and matched group 20 examples:
In test group 40 examples, male 21 examples, women 19 examples, the age is all at 18-60 between year, 18-29 year 10 examples wherein, 30-39 year 14 examples, 40-49 year 10 examples, 50-59 year 2 examples, the elder of the course of disease 8 days, the shortest person 3 days, hot aversion to cold person 16 examples occur together;
In matched group 20 examples, male 12 examples, women 8 examples, the age is also all at 18-60 between year, 18-29 year 5 examples, 30-39 year 7 examples, 40-49 year 5 examples, 50 1 59 years old 3 example, the elder of the course of disease 9 days, the shortest person 4 days, hot none example of aversion to cold person occurs together.
Test group 40 examples all are the treatment group, inpatient's 18 examples wherein, clinic case 22 examples, the inpatient accounts for male 32 examples among 45%, the 40 routine patient of whole number, woman's 8 examples, men and women's ratio is 4: 1, the oldest 56 years old, and minimum 19 years old, mean aves 36 example, the course of disease: prescription on individual diagnosis person 22 people in 1 day, 2 days 32 people, 3 days 20 people, 4 days 2 people, 5 days 2 people account for respectively and observe 30%, 40%, 25%, 2.5%, 2.5% of total number of persons, case classification: acute simple pharyngitis 28 examples, acute episode of chronic pharyngitis person 12 examples account for 70% and 30% of total inspection number respectively; Associated disease: companion oral ulcer person 8 examples account for 20%; The etiology classification: high bacterial infection person 16 examples that merge of hemogram account for 40%, and the other factors person accounts for 60%.The result is test group, clinical cure 18 people, produce effects 14 people, effective 6 people, invalid 2 people, total effective rate is 95%, matched group, clinical cure 1 people, produce effects 6 people, effective 9 people, invalid 4 people, total effective rate 80% is learned by statistics and is handled, and two groups of curative effects have utmost point significant difference, and two groups of cure rates compare X
2=9.858798 P＜0.005 liang group is relatively comprehensive: U=3.643, P＜0.001.
2, according to acute pharyngitis patient's symptom, pharyngeal sign, temperature taking, be divided into light, in, weigh three grades, quantitative criterion is carried out with reference to symptom hierarchical table (table 1), judges that according to the variation of (own control) every index before and after the medication this medication imitates then.If test group (medicine of the present invention) and matched group (Waterelon Frost Lozenges).
Table 1 tcm symptom is light, in, the weight classification standard scale
Observed result: two groups of total effectses compare: in test group 120 examples, clinical cure 54 examples account for 45%, produce effects 38 examples, account for 31.67%, 23 examples that take a turn for the better account for 19.17%, invalid 5 examples, account for 4.17%, total effective rate 95.84%, in matched group 40 examples, clinical cure 4 examples, account for 10%, produce effects 13 examples account for 32.5%, and 17 examples take a turn for the better, account for 42.5%, invalid 6 examples account for 15%, total effective rate 85%, test group is better than matched group, two groups of X
2Check, the result has significant difference (P＜0.05), and two groups of results of comparison see Table 2.
Table 2: two groups of total effectses relatively
| Group n | Clinical recovery (%) | Produce effects (%) | Take a turn for the better (%) | Invalid (%) | Total effective rate |
| Test group 120 | 54 | 38(31.67) | 23(19.17) | 5(4.17) | 95.84％ |
| Matched group 40 | 4(10) | 13(32.5) | 17(42.5) | 6(15) | 85％ |
As seen from the above table, total effective rate of the present invention is more than 95%, satisfactory effect.
With regard to the symptom of concrete position, as table 3.
Table 3: Chinese medicine tablet of the present invention (grain) improves the effect of cardinal symptom:
| Symptom | Before the treatment | After the treatment | The improvement rate |
| Pharyngalgia | 116 examples | 7 examples | 94％ |
| Dysphagia | 100 examples | 5 examples | 95％ |
| Parched throat is scorching hot | 96 examples | 3 examples | 97％ |
As seen from the above table, the present invention has significantly curative effect to the cardinal symptom of acute pharyngitis.
3, leukocyte situation of change before and after the treatment, the leukocyte person of increasing 32 examples in test group 120 examples, treatment back 26 examples recover normal, the leukocyte person of increasing 5 examples in matched group 40 examples, treatment back 3 examples recover normal, and (seeing Table 4) illustrates that the present invention has certain effect to reducing leukocyte.
Table 4: two groups of leukocyte change before and after the treatment
| Group | The example number | Before the treatment＞10 * 10 9/L | Treatment back＞10 * 10 9/L |
| Test group | 120 | 32 | 6 |
| Matched group | 40 | 5 | 2 |
4, body temperature, hemogram, tongue pulse condition are improved the influence of situation.
Table 5: buccal tablet antipyretic effect of the present invention
| Body temperature | Before the treatment (example) | Treatment back (example) | Curative effect shows (%) |
| 37-38℃ | 12 | 2 | 83 |
| 38-39℃ | 4 | 2 | 50 |
| More than 39 ℃ | 0 | 0 |
As seen from the above table, centering calentura people effect of the present invention is general, but better to low grade fever patient effect.
Table 6: hemogram, tongue pulse condition improve situation
| Body temperature | Before the treatment (example) | Treatment back (example) | Improvement rate (%) |
| WBC＞10×10 9/L | 16 | 8 | 50 |
| The tongue tip side of red white and thin fur | 34 | 11 | 68 |
| Floating and rapid pulse | 36 | 10 | 72 |
As seen from the above table, the present invention has certain effect to reducing leukocyte, and is better to improving the effect of tongue pulse condition.
Before and after the treatment two groups of patients urine, stool routine and BUN, GPT inspection and Electrocardioscopy have all been carried out, two groups of patient BUN, GPT, electrocardiogram results all in normal range, illustrated that this medicine does not have influence, safe and reliable to the heart, liver, renal function before and after the result showed treatment.
Six, conclusion
Show by above-mentioned situation, the present invention is safe and reliable, does not find a routine untoward reaction during the observation patient, and hepatic and renal function is had no adverse effects, the present invention is the active drug of treatment acute pharyngitis, the curative effect height, up to more than 95%, no toxicity, easy to use, actual clinical meaning is arranged, for the acute pharyngitis patient provides the good curing condition, and Chinese medicine of the present invention is also to cleaning oral cavity, the halitosis of dispelling, the treatment oral ulcer has curative effect preferably, functions of prevention and health care of the present invention is obvious, and dry mouth and throat patient's a slice holding in the mouth for dissolving drug is profusely salubrious, the patient takes like a shot, having the good clinical DEVELOPMENT PROSPECT, is that one on the Chinese medicine and pharmacy created greatly, makes and benefits society.
Claims (2)
1. Chinese medicine for the treatment of acute pharyngitis, it is characterized in that, by Folium Perillae 140-160g, Herba Menthae 110-130g, Fructus Mume 200-240g, Fructus Canarii 65-85g, Radix Puerariae 65-85g, Rhizoma Phragmitis 65-85g, Radix Platycodonis 65-85g, Radix Glycyrrhizae 35-45g, Borax 18-22g, Borneolum Syntheticum 0.18-0.22g, sucrose 365-445g and dextrin 49-59g make as raw material, wherein, get the Fructus Mume of above-mentioned recipe quantity, Folium Perillae, Fructus Canarii, Rhizoma Phragmitis, Herba Menthae, Radix Puerariae, Radix Platycodonis and Radix Glycyrrhizae eight flavor medicines, the water that adds 15 times of weight of above-mentioned 8 herbal medicines, extract volatile oil with steam distillation, aqueous solution after distillation device is in addition collected, standby, the decocting that medicinal residues add medicinal residues 15-10 times weight boils three times, three decoction liquor are merged, filter, aqueous solution after filtrate and the above-mentioned distillation merges, get mixed liquor, being evaporated to 50 ℃ of following relative densities is 1.1, adding ethanol makes mixed liquor contain the alcohol amount to reach 20%, left standstill 24 hours, the centrifugal precipitation of removing, supernatant filters, decompression filtrate recycling ethanol, and to be condensed into 50 ℃ of following relative densities be 1.4 extractum, add sucrose and dextrin, make granule, drying; get the Borneolum Syntheticum dissolve with ethanol; above-mentioned granule is added Borax; Borneolum Syntheticum after the dissolving and volatile oil, mixing; cold drying, compacting in flakes.
2. a kind of Chinese medicine for the treatment of acute pharyngitis according to claim 1, it is characterized in that, by Folium Perillae 150g, Herba Menthae 120g, Fructus Mume 220g, Fructus Canarii 75g, Radix Puerariae 75g, Rhizoma Phragmitis 75g, Radix Platycodonis 75g, Radix Glycyrrhizae 40g, Borax 20g, Borneolum Syntheticum 0.2g, sucrose 405g and dextrin 54g make as raw material, get the Fructus Mume of above-mentioned recipe quantity, Folium Perillae, Fructus Canarii, Rhizoma Phragmitis, Herba Menthae, Radix Puerariae, Radix Platycodonis and Radix Glycyrrhizae eight flavor medicines, the water that adds 15 times of weight of above-mentioned 8 herbal medicines, extract volatile oil with steam distillation, aqueous solution after distillation device is in addition collected, standby, medicinal residues decoct with water three times, the water that adds for the first time 15 times of amounts of medicinal residues gross weight, decocted 1.5 hours, the water that adds for the second time 10 times of amounts of medicinal residues gross weight, decocted 1 hour, the water that adds 10 times of amounts of medicinal residues gross weight for the third time, decocted 0.5 hour, three decoction liquor are merged, filter, aqueous solution after filtrate and the above-mentioned distillation merges, get mixed liquor, being evaporated to 50 ℃ of following relative densities is 1.1, adds ethanol, make mixed liquor contain the alcohol amount and reach 20%, left standstill 24 hours, the centrifugal precipitation of removing, supernatant filters, decompression filtrate recycling ethanol, and to be condensed into 50 ℃ of following relative densities be 1.4 extractum, adds sucrose and dextrin, makes granule, dry; as to get the Borneolum Syntheticum dissolve with ethanol, above-mentioned granule is added Borax; Borneolum Syntheticum after the dissolving and volatile oil, mixing; cold drying; with pelleter be pressed into 1000, every weight 0.6g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100641033A CN101474373B (en) | 2009-01-19 | 2009-01-19 | Chinese medicine for treating acute pharyngitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100641033A CN101474373B (en) | 2009-01-19 | 2009-01-19 | Chinese medicine for treating acute pharyngitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101474373A CN101474373A (en) | 2009-07-08 |
| CN101474373B true CN101474373B (en) | 2011-03-16 |
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| CN103444968A (en) * | 2013-01-05 | 2013-12-18 | 胡素芳 | Production method of soft palate health care sugar |
| CN103585415B (en) * | 2013-11-19 | 2015-12-30 | 许江 | A kind of Chinese medicine composition and preparation method thereof and purposes |
| CN103656410B (en) * | 2013-12-13 | 2016-01-13 | 广西桂西制药有限公司 | A kind of Chinese medicine preparation for the treatment of cough and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1135908A (en) * | 1995-12-20 | 1996-11-20 | 铁萱 | Medical food for curing acute and chronic pharyngitis |
| CN101041009A (en) * | 2007-04-20 | 2007-09-26 | 孙晓波 | Chinese traditional medicine compound for treating faucitis |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1135908A (en) * | 1995-12-20 | 1996-11-20 | 铁萱 | Medical food for curing acute and chronic pharyngitis |
| CN101041009A (en) * | 2007-04-20 | 2007-09-26 | 孙晓波 | Chinese traditional medicine compound for treating faucitis |
Non-Patent Citations (1)
| Title |
|---|
| 国家药品监督管理局.《甘桔冰梅片》.《中成药地方标准上升国家标准部分 眼科 耳鼻喉科 皮肤科分册》.2002,第GYB-64页. * |
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