Summary of the invention
It is a kind of effective that technical problem to be solved by this invention is to provide, the safe and reliable Chinese medicine composition for skin whitening.
Technical problem to be solved by this invention realizes by the following technical solutions:
For a Chinese medicine composition for skin whitening, by the crude drug of following weight, formed,
Colla Corii Asini 19-21 gram, Arillus Longan 14-16 gram, Fructus Citri Limoniae 19-21 gram, Semen Coicis 19-21 gram, Radix Scutellariae 14-16 gram, Fructus Lycii 14-16 gram, Fructus Crataegi 19-21 gram, Semen Persicae 11-13 gram, Rhizoma Dioscoreae 14-16 gram, Fructus Mori 14-16 gram, Exocarpium Citri Rubrum 11-13 gram, Rhizoma Polygonati 14-16 gram, Fructus Jujubae 19-21 gram.
Preferred weight part of each crude drug is:
20 grams, Colla Corii Asini, 15 grams of Arillus Longans, 20 grams, Fructus Citri Limoniae, 20 grams of Semen Coicis, 15 grams of Radix Scutellariaes, 15 grams of Fructus Lycii, 20 grams of Fructus Crataegis, 12 grams, Semen Persicae, 15 grams of Rhizoma Dioscoreaes, 15 grams of Fructus Mori, 12 grams of Exocarpium Citri Rubrums, 15 grams of Rhizoma Polygonatis, 20 grams, Fructus Jujubae.
The present invention's crude drug used can be bought and obtain from common Chinese shop, and its specification meets national Chinese crude drug standard.
Another object of the present invention is to provide a kind of method of preparing the present composition, comprises the steps,
1) by the described weight of prescription, take each taste crude drug;
2) by above-mentioned each taste crude drug pulverization, incapsulate.
1, pharmacology analysis:
Colla Corii Asini: the YIN nourishing of enriching blood, moisturize hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Arillus Longan: invigorating the heart and spleen, nourishing blood to tranquillize the mind.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.
Fructus Citri Limoniae: sour in the mouth is sweet, property is flat, enters liver, stomach warp.There is preventing phlegm from forming and stopping coughing, promote the production of body fluid, the effect of spleen invigorating.
Semen Coicis: revisal gas, sharp the intestines and stomach, detumescence, removes pathogen in the heart.
Radix Scutellariae: heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.
Fructus Lycii: regulate body's immunity, can effectively suppress tumor growth and cell mutation, there is slow down aging, the effect of the aspect such as anti-fatty liver, adjusting blood fat and blood glucose.
Fructus Crataegi: the immunity of enhancing body, has anti-aging, anticancer effect.
Semen Persicae: blood stasis removing and clots absorbing; Moisturize laxation.
Rhizoma Dioscoreae: sweet, flat.Strengthening the spleen and stomach, lung benefiting kidney, tonify deficiency are won.
Fructus Mori: nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Exocarpium Citri Rubrum: cold expelling, dampness, promoting the circulation of QI, expectorant.
Rhizoma Polygonati: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.
Fructus Jujubae: there is the effects such as tonify deficiency QI invigorating, nourishing blood to tranquillize the mind, invigorating the spleen and regulating the stomach.
2, usage and consumption:
The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as age of patient, body weight, health status.
Instruction: each 6, every day 3 times, the morning, noon and afternoon take, be 1 month a course for the treatment of.
3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and treatment disease, and the use link that this medicine is dropped into treatment disease provides science and objective foundation.
Its test method and result of the test are as follows respectively:
1) capsule of being prepared by the present invention carries out animal acute toxicity test:
Medicine: the present invention's crude drug used is bought and obtained from common Chinese shop, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is in 50g left and right, and male and female are selected at random, by market, are bought.
Method and result: get 30 of white mice, hungry about 20 hours, by filling with several times every every day, feed 50g, feed one week continuously, to observe 10 days, mice is movable normal, and non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) capsule of being prepared by the present invention carries out long-term toxicity test for animals:
Experimental animal: rat, body weight is at 120-130g, and male and female are selected at random, by market, are bought.
Method and result: get 20 of rat, be divided into 2 groups, every group 10, wherein the 1st group as administration group, by filling with several times every every day, feed 40-50g, the 2nd group of normal feeding as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the variation of tissues observed form, observe the effect of dosage, observe diet, movable variation, experimental results show that administration group and matched group are relatively without significant change, equal non-toxic reaction, a kind of safe drugs.
4, diagnostic criteria
1) clinical diagnosis: face has chloasma in various degree, xerosis cutis,, easily ftracture, senile plaque, freckle, the symptoms such as pigmentation.
2) in order to verify clinical efficacy, this prescription is tried out in First People's Hospital, Jieshou City, Anhui Province respectively, chooses at random wherein 50 routine female patients.
3) Therapeutic Method: take capsule of the present invention, divide for each person every day and take for three times, one time 6, take continuously 1 month.
4) efficacy determination:
Recovery from illness: mottle all disappears, skin smooth, seamless.
Effective: mottle disappears more than 80%.
Effective: mottle disappears more than 10%, part color is thin out.
Invalid: the symptoms such as mottle are unchanged or worsen.
Concrete therapeutic outcome is referring to table 1;
Table 1
Number of cases |
Recovery from illness |
Effective |
Effectively |
Invalid |
Effective percentage (%) |
50 |
10 |
20 |
19 |
1 |
98 |
5, points for attention:
1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.
2. child, women breast-feeding their children, elderly and infirm should take under doctor instructs.
3. driver, work high above the ground person are cautious use of.
4. strictly by usage and dosage, take.
5. pair this medicine and ethanol allergy sufferers are forbidden, and allergic constitution person be cautious use of.
6. when this property of drug changes, ban use of.
7. please this medicine is placed on to the place that child can not contact.
8. as use other medicines, using please Ref Dr or pharmacist before this medicine.
The invention has the beneficial effects as follows: the present invention is formed by multiple prepared from traditional Chinese medicines, can dredging the meridian, benefiting qi and nourishing blood blood stasis dispelling, invigorating kidney, promoting blood circulation, reinforce insufficiency and reduce excessiveness, soothing the liverly repose, internal organs integral body is carried out to dynamic equilibrium, reverse endocrine regulation, improve hemorheology index, take good care of combination, there is taking convenience, feature that drug cost is low.
The specific embodiment
For technological means, creation characteristic that the present invention is realized, reach object and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.
Embodiment 1
By following weight, take each crude drug: 20 grams, Colla Corii Asini, 15 grams of Arillus Longans, 20 grams, Fructus Citri Limoniae, 20 grams of Semen Coicis, 15 grams of Radix Scutellariaes, 15 grams of Fructus Lycii, 20 grams of Fructus Crataegis, 12 grams, Semen Persicae, 15 grams of Rhizoma Dioscoreaes, 15 grams of Fructus Mori, 12 grams of Exocarpium Citri Rubrums, 15 grams of Rhizoma Polygonatis, 20 grams, Fructus Jujubae.By above-mentioned each taste crude drug pulverization, be prepared into according to a conventional method capsule.
Embodiment 2
By following weight, take each crude drug: 21 grams, Colla Corii Asini, 16 grams of Arillus Longans, 21 grams, Fructus Citri Limoniae, 21 grams of Semen Coicis, 16 grams of Radix Scutellariaes, 16 grams of Fructus Lycii, 21 grams of Fructus Crataegis, 13 grams, Semen Persicae, 16 grams of Rhizoma Dioscoreaes, 16 grams of Fructus Mori, 13 grams of Exocarpium Citri Rubrums, 16 grams of Rhizoma Polygonatis, 21 grams, Fructus Jujubae.By above-mentioned each taste crude drug pulverization, be prepared into according to a conventional method capsule.
Embodiment 3
By following weight, take each crude drug: 19 grams, Colla Corii Asini, 14 grams of Arillus Longans, 19 grams, Fructus Citri Limoniae, 19 grams of Semen Coicis, 14 grams of Radix Scutellariaes, 14 grams of Fructus Lycii, 19 grams of Fructus Crataegis, 11 grams, Semen Persicae, 14 grams of Rhizoma Dioscoreaes, 14 grams of Fructus Mori, 11 grams of Exocarpium Citri Rubrums, 14 grams of Rhizoma Polygonatis, 19 grams, Fructus Jujubae.By above-mentioned each taste crude drug pulverization, be prepared into according to a conventional method capsule.
Model case:
Case 1
Scheme certain, female, 28 years old.Because of working principle, be all in the face of computer every day, causes face dry, although all used skin-protection product every day, effect is always not good.After take capsule of the present invention, after 4 courses for the treatment of, effect manifests, it is glossy, pale, flexible that skin becomes.
Case 2
Side so-and-so, female, 40 years old.There is chloasma in face, relevant with face, no conscious sympton.Take 2 months chloasma of capsule of the present invention and disappear, face is lubricated glossy.
Case 3
Thank certain, female, 38 years old.Live in rural area, often need to do farm work, xerosis cutis, pigmentation, easy bursting by freezing in winter.Take capsule of the present invention after 4 courses for the treatment of, xerosis cutis problem is effectively solved, after taken continuously again 8 courses for the treatment of, moisture of skin is better, follows up a case by regular visits to 1 year, does not occur bursting by freezing phenomenon winter.
Case 4
Huang, female, 32 years old.Face is long has freckle for many years, and the black Huang of skin, has used a lot of speckle dispelling product, and effect is undesirable, takes 4 courses for the treatment of of capsule of the present invention, and freckle disappears, and blee bleaches.
More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.