CN103656579A - Traditional Chinese medicine composition for relieving cough - Google Patents

Traditional Chinese medicine composition for relieving cough Download PDF

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Publication number
CN103656579A
CN103656579A CN201310669735.9A CN201310669735A CN103656579A CN 103656579 A CN103656579 A CN 103656579A CN 201310669735 A CN201310669735 A CN 201310669735A CN 103656579 A CN103656579 A CN 103656579A
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parts
radix
chinese medicine
rhizoma
traditional chinese
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CN201310669735.9A
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CN103656579B (en
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权威宇
李加美
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Shandong Zhongda Pharmaceutical Co Ltd
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Shandong Zhongda Pharmaceutical Co Ltd
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Abstract

The invention relates to the field of a traditional Chinese medicine composition, particularly a traditional Chinese medicine composition for relieving cough, which is composed of the following components in parts by weight: 20-30 parts of red tangerine peel, 8-15 parts of dried orange peel, 10-20 parts of tuber pinellia, 8-12 parts of tuckahoe, 6-8 parts of balloonflower, 15-25 parts of almond, 15-25 parts of perilla-seed, 6-8 parts of aster, 3-4 parts of coltsfoot flower, 15-25 parts of trichosanthes kirilowii Maxim peel, 20-30 parts of fritillaria cirrhosa, 15-25 parts of radix rehmanniae, 10-15 parts of ophiopogon root, 13-18 parts of ginger, 10-15 parts of stemona, 6-10 parts of Charred Triplet, 8-10 parts of radix scutellariae, 3-5 parts of rhizoma anemarrhenae and 3-8 parts of rhubarb. The traditional Chinese medicine composition has favorable cough relieving effect; the total effective rate is 100%, and the cure rate is higher than 87.5%; and the traditional Chinese medicine composition is also effective for dry mouth, chest distress, lung-heat and other symptoms.

Description

A kind of cough relief traditional Chinese medicine compositions
Technical field
The present invention relates to Chinese medicine composition field, more specifically a kind of cough relief traditional Chinese medicine compositions.
Background technology
Cough is the common disease of autumn and winter season, is also the protective response of the person, as careless while having a meal, and when the grain of rice is choked into trunnion, can foreign body be discharged by violent cough; While having again the tracheitis of generation, pneumonia, by coughing, coughing up phlegm, the antibacterial in lung and disorganization product can be excreted.And if for the treatment inappropriate medication of cough, not only can not cough-relieving, can increase the weight of the state of an illness on the contrary.
A lot of people think that cough need not treat, and shoulder once having shouldered over.In fact, if initial can not get occurring in cough treated timely and effectively, being easy to make to cough frequent outbreak, causing having sore throat, hoarseness, chest pain etc.For cold cough, need to cause enough attention, adopt in time rational Drug therapy.Although central antitussive is as better in codeine antitussive effect, the easy addiction of life-time service, produce to rely on medicine, there will be psychology and the physiological signs such as dysphoria, nausea and vomiting after drug withdrawal, so its application is strictly controlled, and need to buy with prescription.Applying clinically cough medicine is more widely dextromethorphan preparation, antitussive effect is similar to codeine, quick acting in 15~30 minutes, and in effective dose without addiction, a kind of cough medicine that is alternative codeine by world health organisation recommendations, and cough easily follows the symptoms such as lung-heat, uncomfortable in chest and xerostomia, general medicine can only be treated one, can not treat comprehensively.
Summary of the invention
Goal of the invention of the present invention is for above deficiency, and a kind of Chinese medicine composition for the treatment of lung-heat, uncomfortable in chest and cough-relieving is provided.
The present invention is achieved by the following technical solutions:
A cough relief traditional Chinese medicine compositions, it is comprised of following component by weight: Exocarpium Citri Rubrum 20-30 part, Pericarpium Citri Reticulatae 8-15 part, Rhizoma Pinelliae 10-20 part, Poria 8-12 part, Radix Platycodonis 6-8 part, Semen Armeniacae Amarum 15-25 part, Fructus Perillae 15-25 part, Radix Asteris 6-8 part, Flos Farfarae 3-4 part, Pericarpium Trichosanthis 15-25 part, Bulbus Fritillariae Cirrhosae 20-30 part, Radix Rehmanniae 15-25 part, Radix Ophiopogonis 10-15 part, Rhizoma Zingiberis Recens 13-18 part, Radix Stemonae 10-15 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 6-10 part, Radix Scutellariae 8-10 part, Rhizoma Anemarrhenae 3-5 part, Radix Et Rhizoma Rhei 3-8 part.
Optimize, above-mentioned a kind of cough relief traditional Chinese medicine compositions, it is comprised of following component by weight: Exocarpium Citri Rubrum 25-30 part, Pericarpium Citri Reticulatae 10-15 part, Rhizoma Pinelliae 15-20 part, Poria 8-10 part, Radix Platycodonis 6-8 part, Semen Armeniacae Amarum 15-20 part, Fructus Perillae 15-20 part, Radix Asteris 6-8 part, Flos Farfarae 3-4 part, Pericarpium Trichosanthis 15-20 part, Bulbus Fritillariae Cirrhosae 25-30 part, Radix Rehmanniae 20-25 part, Radix Ophiopogonis 10-15 part, Rhizoma Zingiberis Recens 13-15 part, Radix Stemonae 10-13 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 6-8 part, Radix Scutellariae 8-10 part, Rhizoma Anemarrhenae 3-5 part, Radix Et Rhizoma Rhei 5-8 part.
Optimize, above-mentioned Chinese medicine composition is comprised of following component by weight: 26 parts of Exocarpium Citri Rubrums, 15 parts of Pericarpium Citri Reticulataes, 18 parts of the Rhizoma Pinelliaes, 10 parts, Poria, 8 parts of Radix Platycodoniss, 20 parts, Semen Armeniacae Amarum, 20 parts of Fructus Perillaes, 8 parts of Radix Asteriss, 3 parts of Flos Farfaraees, 20 parts of Pericarpium Trichosanthiss, 25 parts of Bulbus Fritillariae Cirrhosaes, 20 parts, the Radix Rehmanniae, 12 parts of Radix Ophiopogonis, 15 parts, Rhizoma Zingiberis Recens. 12 parts of the Radixs Stemonae, 7 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10 parts of Radix Scutellariaes, 4 parts of the Rhizoma Anemarrhenaes, 5 parts of Radix Et Rhizoma Rhei.
The preparation method of above-mentioned a kind of cough relief traditional Chinese medicine compositions, the steps include: to get Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae decocts with water 1-3 time, each 1-2 hour, it is 1.08 extractum a that collecting decoction is concentrated into the density that compares, by the medical material vapor extraction except Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae, in extracting solution, add ethanol to reaching 60% containing alcohol amount, stir evenly, at 8 ℃ standing 24 hours, get supernatant, reclaiming ethanol, to be concentrated into relative density be 1.08 extractum b, merges extractum a, b, is drying to obtain.
The invention has the beneficial effects as follows: cough relief traditional Chinese medicine compositions cough suppressing effect of the present invention is good, its total effective rate 100%, cure rate is higher than 87.5%, and effective equally for symptoms such as xerostomia, uncomfortable in chest, lung-heat.
The specific embodiment
Below in conjunction with specific embodiment, the present invention will be further described, so that those skilled in the art can better understand the present invention, but therefore do not limit the present invention.
Embodiment 1
25 parts of Exocarpium Citri Rubrums, 10 parts of Pericarpium Citri Reticulataes, 15 parts of the Rhizoma Pinelliaes, 8 parts, Poria, 6 parts of Radix Platycodoniss, 15 parts, Semen Armeniacae Amarum, 15 parts of Fructus Perillaes, 6 parts of Radix Asteriss, 3 parts of Flos Farfaraees, 15 parts of Pericarpium Trichosanthiss, 25 parts of Bulbus Fritillariae Cirrhosaes, 20 parts, the Radix Rehmanniae, 10 parts of Radix Ophiopogonis, 13 parts, Rhizoma Zingiberis Recens, 10 parts of the Radixs Stemonae, 6 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 8 parts of Radix Scutellariaes, 3 parts of the Rhizoma Anemarrhenaes, 5 parts of Radix Et Rhizoma Rhei.
Embodiment 2
30 parts of Exocarpium Citri Rubrums, 15 parts of Pericarpium Citri Reticulataes, 20 parts of the Rhizoma Pinelliaes, 10 parts, Poria, 8 parts of Radix Platycodoniss, 20 parts, Semen Armeniacae Amarum, 20 parts of Fructus Perillaes, 8 parts of Radix Asteriss, 4 parts of Flos Farfaraees, 20 parts of Pericarpium Trichosanthiss, 30 parts of Bulbus Fritillariae Cirrhosaes, 25 parts, the Radix Rehmanniae, 15 parts of Radix Ophiopogonis, 15 parts, Rhizoma Zingiberis Recens, 13 parts of the Radixs Stemonae, 8 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10 parts of Radix Scutellariaes, 5 parts of the Rhizoma Anemarrhenaes, 8 parts of Radix Et Rhizoma Rhei
Embodiment 3
26 parts of Exocarpium Citri Rubrums, 15 parts of Pericarpium Citri Reticulataes, 18 parts of the Rhizoma Pinelliaes, 10 parts, Poria, 8 parts of Radix Platycodoniss, 20 parts, Semen Armeniacae Amarum, 20 parts of Fructus Perillaes, 8 parts of Radix Asteriss, 3 parts of Flos Farfaraees, 20 parts of Pericarpium Trichosanthiss, 25 parts of Bulbus Fritillariae Cirrhosaes, 20 parts, the Radix Rehmanniae, 12 parts of Radix Ophiopogonis, 15 parts, Rhizoma Zingiberis Recens. 12 parts of the Radixs Stemonae, 7 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10 parts of Radix Scutellariaes, 4 parts of the Rhizoma Anemarrhenaes, 5 parts of Radix Et Rhizoma Rhei.
Above-described embodiment all adopts that the method for being prepared as follows is got Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae decocts with water 1-3 time, each 1-2 hour, it is 1.08 extractum a that collecting decoction is concentrated into the density that compares, and by the medical material vapor extraction except Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae, adds ethanol to reaching 60% containing alcohol amount in extracting solution, stir evenly, at 8 ℃ standing 24 hours, get supernatant, reclaiming ethanol, to be concentrated into relative density be 1.08 extractum b, merge extractum a, b, be drying to obtain.
Clinical trial:
Test 1 group (control Example 1), case 120 people, age 15-45 year, medical history 1 day-30 days, the state of an illness: cough, and follow lung-heat, xerostomia and the symptom such as uncomfortable in chest; Every day three times, one after each meal,, 7 days courses for the treatment of, takes two courses for the treatment of by each 6 grams;
Test 2 groups (control Example 2), experiment 3 groups (control Example 3) and test 1 group of indices and all have comparability (P>0.05), three groups all basically identical in sex, age, the course of disease, symptom and sign, has comparability.
Cure: cough lung-heat, xerostomia and the transference cure such as uncomfortable in chest, and without recurrence;
Effective: cough lung-heat, xerostomia and the symptom such as uncomfortable in chest are obviously improved;
Effectively; Cough lung-heat, xerostomia and the symptom such as uncomfortable in chest are improved;
Invalid: cough lung-heat, xerostomia and the symptom such as uncomfortable in chest are substantially unchanged.
The results are shown in Table l.
Table 1
? Cure Effective Effectively Invalid Cure rate Total effective rate
Experimental group 1 106 8 6 0 88.33 100%
Experimental group 2 112 4 2 0 93.33 100%
Experimental group 3 105 8 7 0 87.50 100%
From table l, cough relief traditional Chinese medicine compositions cough suppressing effect of the present invention is good, its total effective rate 100%, and cure rate is higher than 87.5%, and effective equally for symptoms such as xerostomia, uncomfortable in chest, lung-heat.

Claims (4)

1. a cough relief traditional Chinese medicine compositions, it is comprised of following component by weight: Exocarpium Citri Rubrum 20-30 part, Pericarpium Citri Reticulatae 8-15 part, Rhizoma Pinelliae 10-20 part, Poria 8-12 part, Radix Platycodonis 6-8 part, Semen Armeniacae Amarum 15-25 part, Fructus Perillae 15-25 part, Radix Asteris 6-8 part, Flos Farfarae 3-4 part, Pericarpium Trichosanthis 15-25 part, Bulbus Fritillariae Cirrhosae 20-30 part, Radix Rehmanniae 15-25 part, Radix Ophiopogonis 10-15 part, Rhizoma Zingiberis Recens 13-18 part, Radix Stemonae 10-15 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 6-10 part, Radix Scutellariae 8-10 part, Rhizoma Anemarrhenae 3-5 part, Radix Et Rhizoma Rhei 3-8 part.
2. a kind of cough relief traditional Chinese medicine compositions according to claim 1, it is comprised of following component by weight: Exocarpium Citri Rubrum 25-30 part, Pericarpium Citri Reticulatae 10-15 part, Rhizoma Pinelliae 15-20 part, Poria 8-10 part, Radix Platycodonis 6-8 part, Semen Armeniacae Amarum 15-20 part, Fructus Perillae 15-20 part, Radix Asteris 6-8 part, Flos Farfarae 3-4 part, Pericarpium Trichosanthis 15-20 part, Bulbus Fritillariae Cirrhosae 25-30 part, Radix Rehmanniae 20-25 part, Radix Ophiopogonis 10-15 part, Rhizoma Zingiberis Recens 13-15 part, Radix Stemonae 10-13 part, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 6-8 part, Radix Scutellariae 8-10 part, Rhizoma Anemarrhenae 3-5 part, Radix Et Rhizoma Rhei 5-8 part.
3. a kind of cough relief traditional Chinese medicine compositions according to claim 2, is characterized in that: described Chinese medicine composition is comprised of following component by weight: 26 parts of Exocarpium Citri Rubrums, 15 parts of Pericarpium Citri Reticulataes, 18 parts of the Rhizoma Pinelliaes, 10 parts, Poria, 8 parts of Radix Platycodoniss, 20 parts, Semen Armeniacae Amarum, 20 parts of Fructus Perillaes, 8 parts of Radix Asteriss, 3 parts of Flos Farfaraees, 20 parts of Pericarpium Trichosanthiss, 25 parts of Bulbus Fritillariae Cirrhosaes, 20 parts, the Radix Rehmanniae, 12 parts of Radix Ophiopogonis, 15 parts, Rhizoma Zingiberis Recens. 12 parts of the Radixs Stemonae, 7 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 10 parts of Radix Scutellariaes, 4 parts of the Rhizoma Anemarrhenaes, 5 parts of Radix Et Rhizoma Rhei.
4. the preparation method of a kind of cough relief traditional Chinese medicine compositions according to claim 1, the steps include: to get Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae decocts with water 1-3 time, each 1-2 hour, it is 1.08 extractum a that collecting decoction is concentrated into the density that compares, by the medical material vapor extraction except Exocarpium Citri Rubrum, Pericarpium Citri Reticulatae, in extracting solution, add ethanol to reaching 60% containing alcohol amount, stir evenly, at 8 ℃ standing 24 hours, get supernatant, reclaiming ethanol, to be concentrated into relative density be 1.08 extractum b, merges extractum a, b, is drying to obtain.
CN201310669735.9A 2013-12-11 2013-12-11 A kind of cough relief traditional Chinese medicine compositions Expired - Fee Related CN103656579B (en)

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Cited By (4)

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Publication number Priority date Publication date Assignee Title
CN104127738A (en) * 2014-08-18 2014-11-05 青岛百慧智业生物科技有限公司 Traditional Chinese medicine for treating bronchiectasia caused by phlegm-heat obstructing lung and a preparation method thereof
CN104771658A (en) * 2015-04-26 2015-07-15 张昌莲 Traditional Chinese medicine composition for treating cough
WO2020042194A1 (en) * 2018-09-02 2020-03-05 王芹 Fabric for preventing and treating pharyngolaryngitis
CN113952429A (en) * 2021-12-01 2022-01-21 塔里木大学 Traditional Chinese medicine composition for preventing and treating endotoxin-mediated acute lung injury and preparation method thereof

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CN1840119A (en) * 2006-01-23 2006-10-04 北京因科瑞斯生物制品研究所 Antibacterial anti-inflammation capsule and preparation method thereof
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104127738A (en) * 2014-08-18 2014-11-05 青岛百慧智业生物科技有限公司 Traditional Chinese medicine for treating bronchiectasia caused by phlegm-heat obstructing lung and a preparation method thereof
CN104771658A (en) * 2015-04-26 2015-07-15 张昌莲 Traditional Chinese medicine composition for treating cough
WO2020042194A1 (en) * 2018-09-02 2020-03-05 王芹 Fabric for preventing and treating pharyngolaryngitis
CN113952429A (en) * 2021-12-01 2022-01-21 塔里木大学 Traditional Chinese medicine composition for preventing and treating endotoxin-mediated acute lung injury and preparation method thereof

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