CN102526645B - Medicament for treating dysthymic disorder - Google Patents
Medicament for treating dysthymic disorder Download PDFInfo
- Publication number
- CN102526645B CN102526645B CN 201210078777 CN201210078777A CN102526645B CN 102526645 B CN102526645 B CN 102526645B CN 201210078777 CN201210078777 CN 201210078777 CN 201210078777 A CN201210078777 A CN 201210078777A CN 102526645 B CN102526645 B CN 102526645B
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- China
- Prior art keywords
- parts
- medicament
- treatment
- dysthymic disorder
- dysthymia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000003814 drug Substances 0.000 title claims abstract description 16
- 208000024732 dysthymic disease Diseases 0.000 title claims abstract description 14
- 241000628997 Flos Species 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 240000000559 Albizia odoratissima Species 0.000 claims description 2
- 235000011438 Albizia odoratissima Nutrition 0.000 claims description 2
- 241000605447 Anemarrhena Species 0.000 claims description 2
- 235000014375 Curcuma Nutrition 0.000 claims description 2
- 244000164439 Curcuma angustifolia Species 0.000 claims description 2
- 241000208966 Polygala Species 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 240000007185 Albizia julibrissin Species 0.000 abstract 1
- 235000011468 Albizia julibrissin Nutrition 0.000 abstract 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 abstract 1
- 240000006766 Cornus mas Species 0.000 abstract 1
- 241000893536 Epimedium Species 0.000 abstract 1
- 241001080798 Polygala tenuifolia Species 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000008422 Schisandra chinensis Nutrition 0.000 abstract 1
- 235000017803 cinnamon Nutrition 0.000 abstract 1
- 235000018905 epimedium Nutrition 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000004547 Hallucinations Diseases 0.000 description 1
- 206010027940 Mood altered Diseases 0.000 description 1
- 206010029333 Neurosis Diseases 0.000 description 1
- 208000028017 Psychotic disease Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 230000003001 depressive effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000007919 dispersible tablet Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- -1 instant Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000015238 neurotic disease Diseases 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicament for treating dysthymic disorder, which is prepared by the following raw materials, by mass, 3-10 parts of schisandra chinensis, 10-20 parts of polygala tenuifolia, 10-30 parts of radix curcumae, 10-30 parts of epimedium herb, 5-15 parts of pericarpium citri reticulatae, 5-10 parts of albizia julibrissin, 5-15 parts of cinnamon, 10-20 parts of fructus ligustri lucidi, 10-20 parts of rhizoma anemarrhenae and 10-20 parts of dogwood. By means of clinical application, the medicament for treating dysthymic disorder has the advantages of being rapid in function, obvious in treatment effect, good in tolerance, low in cost and free of any toxic and side effect.
Description
Technical field
The present invention relates to the psychosis prevention field, specifically, relate to a kind of medicament for the treatment of dysthymia.
Background technology
Dysthymia is easily excited and mental easily tired, normal the be in a bad mood neurosis disorder of worry and psychology physiological symptom of class spirit.Have 25% to be the dysthymia patient in the patients with depression that is in hospital undergoing treatment.Except the symptom of general depression, dysthymia also has the characteristics of oneself, such as the hallucination illusion, therefore very thorny in the clinical treatment treatment.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of dysthymia.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of dysthymia, it is to be made by weight by following bulk drugs: Fructus Schisandrae Chinensis 3-10 part, Radix Polygalae 10-20 part, Radix Curcumae 10-30 part, Herba Epimedii 10-30 part, Pericarpium Citri Reticulatae 5-15 part, Flos Albiziae 5-10 part, Cortex Cinnamomi 5-15 part, Fructus Ligustri Lucidi 10-20 part, Rhizoma Anemarrhenae 10-20 part and Fructus Corni 10-20 part.
Preferably, it is to be made by weight by following bulk drugs: 15 parts of 5 parts of Fructus Schisandrae Chinensis, 15 parts of Radix Polygalaes, 20 parts of Radix Curcumaes, 20 parts of Herba Epimedii, 10 parts of Pericarpium Citri Reticulataes, 5 parts of Flos Albiziaes, 10 parts of Cortex Cinnamomis, 15 parts of Fructus Ligustri Lucidi, 15 parts of the Rhizoma Anemarrhenaes and Fructus Corni.
Preferably, described medicament is tablet, dispersible tablet, instant, powder or granule.
Use natural drug in the medicament for the treatment of dysthymia of the present invention, find through clinical practice, have effect rapidly, therapeutic effect obviously, better tolerance, advantage with low cost, without any side effects.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 powder of the present invention
Get Fructus Schisandrae Chinensis 50 grams, Radix Polygalae 150 grams, Radix Curcumae 200 grams, Herba Epimedii 200 grams, Pericarpium Citri Reticulatae 100 grams, Flos Albiziae 50 grams, Cortex Cinnamomi 100 grams, Fructus Ligustri Lucidi 150 grams, the Rhizoma Anemarrhenae 150 grams and Fructus Corni 150 grams, pulverize, cross 100 mesh sieves, then add sucrose 250 grams, mixing is packed in 100 bags and be get final product.
Experimental example
Diagnostic criteria
" International Classification of Diseases-Di ten editions " that announces according to WHO and APA,American Psychiatric Association " mental disorder Diagnostic Statistical Manual-Di four editions " and Chinese Spirit Obstacles classification and the diagnostic criteria third edition (CCMD-3) are diagnosed dysthymia about the diagnostic criteria of depression, and the eliminating organic disease.Degree of Depression wherein＜8 is divided into normally according to Hamilton depressive scale (HAMD) scoring (24) totally, and 8～18 are divided into slight depression, and 18～24 are divided into the moderate depression, and＞24 are divided into severe depression.The HAMD scoring is referring to " psychiatric department evaluation scale " [M]. Changsha: Hunan science and technology publishing house, 1993, the 122～203 pages.
Choose patient's 40 examples that meet above-mentioned standard, male 20 examples wherein, women 20 examples; 25～45 years old age, average 32 years old.
Treat with the powder that makes among the embodiment 1, wherein one day 3 times, each one bag, treating January is a course for the treatment of.
Criterion of therapeutical effect
The respectively HAMD scoring before and after the record treatment.To subtract a minute rate 〉=75% as clinical recovery, to subtract a minute rate 〉=50% as marked improvement, to subtract a minute rate 〉=30% as progressive, take＜30% as invalid.
Through the observation of a course for the treatment of, find that all patients all meets the standard of clinical recovery, and during whole treatment, do not observe obvious untoward reaction.
Claims (2)
1. medicament for the treatment of dysthymia, it is characterized in that, it is to be made by weight by following bulk drugs: 15 parts of 5 parts of Fructus Schisandrae Chinensis, 15 parts of Radix Polygalaes, 20 parts of Radix Curcumaes, 20 parts of Herba Epimedii, 10 parts of Pericarpium Citri Reticulataes, 5 parts of Flos Albiziaes, 10 parts of Cortex Cinnamomis, 15 parts of Fructus Ligustri Lucidi, 15 parts of the Rhizoma Anemarrhenaes and Fructus Corni.
2. the medicament for the treatment of dysthymia according to claim 1 is characterized in that, described medicament is tablet, powder or granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210078777 CN102526645B (en) | 2012-03-23 | 2012-03-23 | Medicament for treating dysthymic disorder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210078777 CN102526645B (en) | 2012-03-23 | 2012-03-23 | Medicament for treating dysthymic disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102526645A CN102526645A (en) | 2012-07-04 |
| CN102526645B true CN102526645B (en) | 2013-05-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210078777 Expired - Fee Related CN102526645B (en) | 2012-03-23 | 2012-03-23 | Medicament for treating dysthymic disorder |
Country Status (1)
| Country | Link |
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| CN (1) | CN102526645B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877376B (en) * | 2014-04-09 | 2016-09-14 | 山东大学齐鲁医院 | A kind of pharmaceutical preparation treating depression |
| CN104983985B (en) * | 2015-08-04 | 2016-03-16 | 山东中医药大学附属医院 | A kind of Chinese medicine preparation of Cure of depression |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101496865A (en) * | 2009-03-19 | 2009-08-05 | 杨颖� | Chinese medicament preparation for treating depression and anxiety as well as preparation method thereof |
| CN101574499A (en) * | 2009-06-05 | 2009-11-11 | 李振爽 | Capsule for calming heart and tranquilizing mind |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101564495B (en) * | 2009-06-04 | 2012-01-11 | 昝圣旭 | Series medicaments for psychosis negative four-step therapy |
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2012
- 2012-03-23 CN CN 201210078777 patent/CN102526645B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101496865A (en) * | 2009-03-19 | 2009-08-05 | 杨颖� | Chinese medicament preparation for treating depression and anxiety as well as preparation method thereof |
| CN101574499A (en) * | 2009-06-05 | 2009-11-11 | 李振爽 | Capsule for calming heart and tranquilizing mind |
Non-Patent Citations (6)
| Title |
|---|
| 孙素明.郁病辨治经验.《湖北中医杂志》.2004,第26卷(第4期),第46页第2栏. |
| 杜恩伟等.抑郁性神经症辨治七法.《山东中医杂志》.2003,第22卷(第11期),第668-670页. * |
| 杨静娟.中医辨证治疗抑郁性神经症43例疗效观察.《河北中医》.2002,第24卷(第11期),第811-813页. * |
| 段浩等.辨证治疗抑郁性神经症40例.《中医研究》.2000,第13卷(第4期),第36-38页·. |
| 辨证治疗抑郁性神经症40例;段浩等;《中医研究》;20000630;第13卷(第4期);第36页2.2 * |
| 郁病辨治经验;孙素明;《湖北中医杂志》;20040410;第26卷(第4期);第46页第2栏 * |
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| Publication number | Publication date |
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| CN102526645A (en) | 2012-07-04 |
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Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG Free format text: FORMER OWNER: WU YUQIU Effective date: 20130806 |
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Free format text: CORRECT: ADDRESS; FROM: 272051 JINING, SHANDONG PROVINCE TO: 214400 WUXI, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20130806 Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin Address before: 272051 Jining psychiatric hospital, 1 Dai Dai Road, Shandong, Jining Patentee before: Wu Yuqiu |
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Effective date of registration: 20170608 Address after: 226500, No. 999, Wanshou South Road, Rugao City, Jiangsu province (room 3A08-26, building 8, hi tech Zone, Nantong) Patentee after: Jiangsu hundred sword Pharmaceutical Technology Co., Ltd. Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin |
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