Summary of the invention
The objective of the invention is to overcome problems such as single bactericide is single to the agricultural disease preventive and therapeutic effect, lasting period weak point, virulence deficiency, provide a kind of bactericidal effect good, delay pesticide resistance and the low bactericidal composition of drug cost.
Another object of the present invention provides said bactericidal composition is used for the banded sclerotial blight of paddy rice and the purposes of false smut.
The present invention provides a kind of bactericidal composition, and said bactericidal composition contains thifluzamide and tetraconazole, and wherein, the weight ratio of thifluzamide and tetraconazole is 100: 1~1: 100.
Preferably, the weight ratio of thifluzamide and tetraconazole is 15: 1~1: 10.
Bactericidal composition of the present invention also comprises one or more the mixture in weed killer herbicide, insecticide, protective agent, growth regulator, nutrient for plants or the soil conditioner.
The present invention also provides a kind of bactericide, and wherein said bactericide contains the above-mentioned bactericidal composition of 0.1~90 weight %, and surplus is acceptable carrier and an auxiliary agent on the agricultural chemicals.
Preferably, said bactericide contains the above-mentioned bactericidal composition of 5~80 weight %, and surplus is acceptable carrier and an auxiliary agent on the agricultural chemicals.
According to the preferred implementation of bactericide according to the invention, its formulation is suspended emulsion, aqueous emulsion, microemulsion, wetting powder or water dispersible granules.
The present invention also provides above-mentioned bactericidal composition in the application that prevents and treats rice sheath blight disease and false smut.
The present invention also provides a kind of method of preventing and treating crop pest, before or after crops and/or fruit introduced disease, uses above-mentioned bactericidal composition or above-mentioned bactericide to the place of crops and/or fruit and growth or storage.
Below technical scheme of the present invention will be described in more detail:
The present invention provides a kind of bactericidal composition, and said bactericidal composition contains thifluzamide and tetraconazole, and wherein, the weight ratio of thifluzamide and tetraconazole is 100: 1~1: 100, particularly preferably 15: 1~1: 10.
The present invention also provides the bactericide that contains above-mentioned bactericidal composition, and said bactericide contains the above-mentioned bactericidal composition of 0.1~90 weight %, and surplus is acceptable carrier and an auxiliary agent on the agricultural chemicals.Particularly preferably, the content of above-mentioned bactericidal composition is 5~80 weight %.
Bactericidal composition of the present invention can also comprise one or more the mixture in weed killer herbicide, insecticide, protective agent, growth regulator, nutrient for plants or the soil conditioner.Said weed killer herbicide, insecticide, protective agent, growth regulator, nutrient for plants or soil conditioner can be the products of buying acquisition on the market.
Except as otherwise noted, " % " involved in the present invention is " percentage by weight ".
According to method known in those skilled in the art, bactericidal composition of the present invention can be mixed with the formulation that allows on the agricultural when practical application, and formulation is suspending agent, suspension emulsion, aqueous emulsion, microemulsion, wetting powder or water dispersible granules preferably.
To suspension emulsion, spendable auxiliary agent has: dispersant is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, TERSPERSE 2425; Wetting agent is selected from alkylphenol-polyethenoxy and gathers basic ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500; Emulsifier is selected from Nonyl pheno (EO=10) ether phosphate, triphen ethyl-phenol polyoxyethylene ether phosphate (agricultural newborn 600# phosphate), Nongru-700 #, agricultural newborn 2201#, Span-60#, emulsifier T-60, TX-10, agricultural newborn 1601#, agricultural newborn 600#, agricultural newborn 400#; Solvent is selected from xylol, toluene, cyclohexanone, solvent naphtha (trade mark: S-150, S-180, S-200); Thickener is selected from xanthans, aluminium-magnesium silicate, bentonite; Preservative is selected from benzoic acid, Sodium Benzoate, BIT (1, the 2-benzisothiazole-3-ketone); Antifoaming agent is silicone based antifoaming agent; Antifreezing agent is selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride.
To aqueous emulsion, spendable auxiliary agent has: emulsifier is selected from Nonyl pheno (EO=10) ether phosphate, triphen ethyl-phenol polyoxyethylene ether phosphate (agricultural newborn 600# phosphate), Nongru-700 #, agricultural newborn 2201#, Span-60#, emulsifier T-60, TX-10, agricultural newborn 1601#, agricultural newborn 600#, agricultural newborn 400#; Solvent is selected from xylol, toluene, cyclohexanone, solvent naphtha (trade mark: S-150, S-180, S-200); Stabilizing agent is selected from triphenyl phosphite, epoxychloropropane; Antifreezing agent is selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride; Thickener is selected from xanthans, bentonite, aluminium-magnesium silicate; Preservative is selected from BIT (1, the 2-benzisothiazole-3-ketone), benzoic acid, Sodium Benzoate.
To microemulsion, spendable auxiliary agent has: emulsifier is selected from calcium dodecyl benzene sulfonate (agricultural newborn 500#), Nongru-700 #, agricultural newborn 2201#, this dish-60#, Tween-80, TX-10, farming breast 1601, agricultural newborn 600#, agricultural newborn 400#; Cosolvent is selected from methyl alcohol, isopropyl alcohol, n-butanol, ethanol; Solvent is selected from cyclohexanone, N-Methyl pyrrolidone, xylol, toluene, solvent naphtha (trade mark: S-150, S-180, S-200); Stabilizing agent is selected from triphenyl phosphite, epoxychloropropane.
To wetting powder, spendable auxiliary agent has: dispersant is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate; Wetting agent is selected from alkyl sulfate, alkylsulfonate, naphthalene sulfonate; Filler is selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay etc.
For water dispersible granules, those skilled in the art are familiar with the use corresponding adjuvants and accomplish the present invention very much.Dispersant is selected for use from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate; Wetting agent is selected from polyoxyethylene alcohol, alkyl sulfate, alkylsulfonate, naphthalene sulfonate; Disintegrant is selected from ammonium sulfate, urea, sucrose, glucose, citric acid, succinic acid, sodium bicarbonate; Binding agent is selected from diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family and microcrystalline cellulose class; Filler is selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, sepiolite, talcum powder, attapulgite, potter's clay etc.
Bactericidal composition of the present invention can provide with the finished product preparation form, and promptly each material mixes in the composition; Also can provide, in bucket (jar), directly mix before using with single agent formulation.Concentrate of the present invention mixes the concentration that obtains required active substance usually with water.
The present invention also provides above-mentioned bactericidal composition in the application that prevents and treats rice sheath blight disease and false smut.
The present invention also provides a kind of method of preventing and treating crop pest, before or after crops and/or fruit introduced disease, uses above-mentioned bactericidal composition or above-mentioned bactericide to the place of crops and/or fruit and growth or storage.
Compared with prior art, the present invention is through the use of uniting of thifluzamide and tetraconazole, and its beneficial effect is:
(1) compare with single agent, bactericidal composition according to the invention has significant synergistic effect to disease, has improved bactericidal effect;
(2) reduce the medication number of times, reduce drug cost, reduce environmental pollution and residue of pesticide;
(3) composition is made up of the active ingredient of different effects mechanism, and the action site increase helps overcoming and delays the drug-fast generation of germ.
Embodiment
Come the present invention is further specified below in conjunction with specific embodiment, but do not limit the invention to these embodiments.One skilled in the art would recognize that the present invention contained in claims scope all alternatives, improvement project and the equivalents that possibly comprise.
One, preparation embodiment
Related " % " all is weight percentage in following all preparation proportionings.
1, preparation suspended emulsion
Press formula rate, former medicine and dispersant, wetting agent, antifoaming agent, water etc. are mixed, obtain the suspension mother liquor through the sand mill sand milling; Again another former medicine, solvent, emulsifier etc. are mixed, obtain the homogeneous oil phase, according to metering proportion, under high shear conditions, with oil phase and excess water join mix in the suspension mother liquor shear even.Adding thickener and preservative again stirs and obtains required product.
Embodiment 1:40% thifluzamide tetraconazole suspended emulsion (active ingredient was than 1: 1)
Take by weighing the former medicine of 20% thifluzamide, the former medicine of 20% tetraconazole, 4%FS3000 (phosphate type anion surfactant), 1%SXC (sulfonic acid type anion surfactant), 30% solvent naphtha S150,5% farming breast 500,1%NS-500LQ, 0.1% xanthans, 5% ethylene glycol, 0.03%BIT (1; The 2-benzisothiazole-3-ketone), 0.3% organically-modified silicone antifoam agent, deionized water adds to 100%.
Earlier the former medicine of thifluzamide, FS3000, SXC, ethylene glycol, antifoaming agent, part deionized water are mixed, obtain thifluzamide suspension mother liquor in the sand mill sand milling.Again the former medicine of tetraconazole, solvent naphtha, emulsifiers dissolve are mixed and obtain the homogeneous oil phase, according to metering proportion, under high shear conditions (rotating speed 3000r/min for example, 10min), with oil phase and excess water join mix in the suspension mother liquor shear even.Adding thickener xanthans and preservative BIT again mixes and obtains required product.
Embodiment 2:24% thifluzamide tetraconazole suspended emulsion (active ingredient was than 5: 1)
Take by weighing the former medicine of 20% thifluzamide, the former medicine of 4% tetraconazole, 3%FS3000,1%JFC (AEO), 20% solvent naphtha S150,3% farming breast 500,1%NS-500LQ, 0.2% xanthans, 5% ethylene glycol, 0.3% benzoic acid, 0.4% organically-modified silicone antifoam agent, deionized water adds to 100%.
Earlier the former medicine of thifluzamide, FS3000, JFC, ethylene glycol, antifoaming agent, part deionized water are mixed, obtain thifluzamide suspension mother liquor in the sand mill sand milling.Again the former medicine of tetraconazole, solvent naphtha, emulsifiers dissolve are mixed and obtain the homogeneous oil phase, according to metering proportion, under high shear conditions, with oil phase and excess water join mix in the suspension mother liquor shear even.Adding thickener xanthans and preservative BIT again mixes and obtains required product.
2, water dispersible granules
Embodiment 3:30% thifluzamide tetraconazole water dispersible granules (active ingredient was than 5: 1)
Take by weighing the former medicine of 25% thifluzamide, the former medicine of 5% tetraconazole, 3.5%NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 2.5% Nekal BX (nekal), 3%K-12 (lauryl sodium sulfate), 5% carboxymethyl (ethyl) cellulose, 3% diatomite, 5% glucose, kaolin and add to 100%.
Press formula rate, former medicine and dispersant, wetting agent, binding agent, filler etc. are mixed, behind comminution by gas stream, obtain pulvis, add a certain amount of water and mix, in comminutor, carry out granulation, dry then, screening promptly gets granular product.
Embodiment 4:33% thifluzamide tetraconazole water dispersible granules (active ingredient was than 1: 10)
Take by weighing the former medicine of 3% thifluzamide, the former medicine of 30% tetraconazole, 3.5%NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 2.5% Nekal BX (nekal), 3%K-12 (lauryl sodium sulfate), 5% carboxymethyl (ethyl) cellulose, 20% diatomite, 5% glucose, kaolin and add to 100%.
The preparation process is with embodiment 3.
3, wetting powder
By the prescription requirement, various auxiliary agents, filler, former medicine are mixed after after the Roughpulverizer pulverizing, get into airslide disintegrating mill and fully pulverize the mixed wetting powder that gets.
Embodiment 5:60% thifluzamide tetraconazole wetting powder (active ingredient was than 5: 1)
Take by weighing the former medicine of 50% thifluzamide, the former medicine of 10% tetraconazole, 4%NNO, 2% Nekal BX, 5% white carbon, fine particle calcium carbonate and add to 100%.Mix, obtain product after the pulverizing.
Embodiment 6:80% thifluzamide tetraconazole wetting powder (active ingredient was than 3: 1)
Take by weighing the former medicine of 60% thifluzamide, the former medicine of 20% tetraconazole, 5% calcium lignosulfonate, 4%NNO, 2%K-12,4% white carbon, kaolin and add to 100%.Mix, obtain product after the pulverizing.
4, microemulsion
Embodiment 7:16% thifluzamide tetraconazole microemulsion (active ingredient was than 15: 1)
Take by weighing the former medicine of 15% thifluzamide, the former medicine of 1% tetraconazole, 5% Nongru-700 #, 5% agricultural newborn 500#, 6% agricultural newborn 1601#, 15% cyclohexanone, 5%N-methyl pyrrolidone, 5% n-butanol; Through dissolving fully and mixing, deionized water adds to 100%.After stirring, obtain product.
Embodiment 8:22% thifluzamide tetraconazole microemulsion (active ingredient was than 10: 1)
Take by weighing the former medicine of 20% thifluzamide, the former medicine of 2% tetraconazole, 5% agricultural newborn 2201#, 5% agricultural newborn 500#, 6% agricultural newborn 1601#, 15% cyclohexanone, 5%N-methyl pyrrolidone, 5% isopropyl alcohol; Through dissolving fully and mixing, deionized water adds to 100%.After stirring, obtain product.
Embodiment 9:36% thifluzamide tetraconazole microemulsion (active ingredient was than 1: 5)
Take by weighing the former medicine of 6% thifluzamide, the former medicine of 30% tetraconazole, 5% agricultural newborn 2201#, 5% agricultural newborn 500#, 6% agricultural newborn 1601#, 15% cyclohexanone, 5%N-methyl pyrrolidone, 5% isopropyl alcohol; Through dissolving fully and mixing, deionized water adds to 100%.After stirring, obtain product.
5, aqueous emulsion
Embodiment 10:5% thifluzamide tetraconazole aqueous emulsion (active ingredient was than 4: 1)
Take by weighing the former medicine of 4% thifluzamide, the former medicine of 1% tetraconazole, 3% agricultural newborn 2201#, 2% Nonyl pheno (EO=10) ether phosphate, 2% agricultural newborn 600# acid phosphatide, 15% cyclohexanone, 10% solvent naphtha S150, mixed dissolution obtains oil phase.With 5% ethylene glycol, 0.3% xanthans, 0.03%BIT (1, the 2-benzisothiazole-3-ketone), deionized water adds to 100%, is made into water.Oil phase adds aqueous phase and fully mixes, and behind high-shear emulsifying, obtains product.
Embodiment 11:11% thifluzamide tetraconazole aqueous emulsion (active ingredient was than 1: 10)
Take by weighing the former medicine of 1% thifluzamide, the former medicine of 10% tetraconazole, 3% agricultural newborn 2201#, 2% Nonyl pheno (EO=10) ether phosphate, 2% agricultural newborn 600# acid phosphatide, 15% cyclohexanone, 10% solvent naphtha S150, mixed dissolution obtains oil phase.With 5% ethylene glycol, 0.3% xanthans, 0.03%BIT (1, the 2-benzisothiazole-3-ketone), deionized water adds to 100%, is made into water.Oil phase adds aqueous phase and fully mixes, and behind high-shear emulsifying, obtains product.
Two, biologically active embodiment
Biologically active embodiment is divided into indoor biologically active embodiment and land for growing field crops biologically active embodiment.
Active instance 1: the composite Toxicity Determination of thifluzamide and tetraconazole to rice sheath blight disease
Experiment target is designated as rice sheath blight disease (Rhizoctonia solani), and test adopts the co-toxicity coefficient method to estimate the co-toxicity effect of complex preparation, clearly than reasonable proportioning.
Thifluzamide and tetraconazole are dissolved with DMF respectively; Be mixed with the soup of series concentration again with 0.1% Tween-80 aqueous solution dilution; In superclean bench, draw the conical flask of 6mL respectively to sterilization; The PDA+100mg/LSHAM medium 54mL that adds about 50 ℃ pours the plate of 4 diameter 9cm into after shaking up, process the toxic medium of 4 respective concentration; Use the same method the thifluzamide and the tetraconazole series concentration compound solution of different proportionings are processed toxic medium.With the rice sheath blight disease pathogen of cultivating 2 days, break into the bacterium piece with the card punch of diameter 5mm at colony edge, with transfer needle the bacterium piece is moved to the toxic PDA medium central authorities that are mixed with in advance, place cultivation in 25 ℃ of incubators then, every processing repetition 4 times.After 3 days, adopt the right-angled intersection method to measure and respectively handle colony diameter cm, obtain to proofread and correct and suppress percentage with slide calliper rule.Two diameters are surveyed in each bacterium colony right-angled intersection, represent the bacterium colony size with its mean.Obtain the colony growth inhibiting rate by following formula: colony growth inhibiting rate %=(the blank bacterium colony increases diameter-chemicals treatment bacterium colony and increases diameter) * 100/ blank bacterium colony increases diameter
On the basis of medicament bacteriostasis rate, carry out the data analysis statistics with " DPS data handling system " 3.11 professional versions, obtain regression line, EC
50, correlation coefficient.EC that each that will measure according to Sun Yunpei (Y-P Sun) method handled
50Be converted into actual poison exponent (ATI); According to the proportioning of mixture, calculate theoretical poison exponent (TTI), calculate the co-toxicity coefficient (CTC) of mixture by following formula.
Theory is used the content (%) of toxicity index * B in using with of content (the %)+B of toxicity index * A in using with of toxicity index (TTI)=A with
If co-toxicity coefficient is greater than 120, showing has synergistic effect; If be starkly lower than 100, be indicated as antagonism; Between 100~120, be indicated as summation action.
The composite Toxicity Determination result of table 1 thifluzamide and tetraconazole to rice sheath blight disease
Medicament |
EC
50(mg/L)
|
ATI |
TTI |
Co-toxicity coefficient CTC |
Conclusion |
Thifluzamide (A) |
7.33 |
70.53 |
|
|
|
Tetraconazole (B) |
5.17 |
100.00 |
|
|
|
A∶B(20∶1) |
6.88 |
75.15 |
71.94 |
104.46 |
Addition |
A∶B(15∶1) |
5.56 |
92.99 |
72.37 |
128.48 |
Synergy |
A∶B(10∶1) |
5.03 |
102.78 |
73.21 |
140.39 |
Synergy |
A∶B(5∶1) |
5.18 |
99.81 |
75.44 |
132.29 |
Synergy |
A∶B(1∶1) |
4.79 |
107.93 |
85.27 |
126.58 |
Synergy |
A∶B(1∶5) |
3.19 |
162.07 |
95.09 |
170.44 |
Synergy |
A∶B(1∶10) |
3.54 |
146.05 |
97.32 |
150.07 |
Synergy |
A∶B(1∶15) |
4.64 |
111.42 |
98.16 |
113.51 |
Addition |
A∶B(1∶20) |
5.13 |
100.78 |
98.60 |
102.21 |
Addition |
Active instance 2: the composite Toxicity Determination of thifluzamide and tetraconazole to rice green smut
Experiment target is designated as rice green smut (Ustilaginoidea virens), and test adopts the co-toxicity coefficient method to estimate the co-toxicity effect of complex preparation, clearly than reasonable proportioning.
Thifluzamide and tetraconazole are dissolved with DMF respectively, be mixed with the soup of series concentration again with 0.1% Tween-80 aqueous solution dilution, again thifluzamide is processed preset series concentration compound solution with tetraconazole respectively by different proportionings.On the PDA medium, cultivated 3 of the mycelia pieces (diameter 5mm) of 14d at 100mL PSB inoculation of medium, 26 ℃ of constant temperature shake the spore mycelia suspension of training 14d, cross the elimination mycelia with the individual layer medical husky cloth of sterilizing, and spore suspension supplies test to use.Preliminary experiment design of series concentration liquid is pressed in each single agent and compound drug respectively, joined and process the pastille liquid nutrient medium in the PSB liquid nutrient medium.Dress dilution 20mL in the triangular flask of every 50mL, 4 bottles of every concentration.Establish blank simultaneously.This process is in strict accordance with sterile working.Every triangular flask adds cultivates subsequent use spore suspension bacterial classification 2mL, and 26 ℃ of constant temperature shake training 12d (rotating speed 120r/min), static cultivation 2d.Pour out mycelia, the mycelia dry weight is claimed in 60 ℃ of oven dry.Calculate the fungistatic effect of each chemicals treatment, bacteriostasis rate (%)=(blank mycelia dry weight-chemicals treatment mycelia dry weight) * 100/ blank mycelia dry weight.
On the basis of medicament bacteriostasis rate, carry out the data analysis statistics with " DPS data handling system " 3.11 professional versions, obtain regression line, EC
50, correlation coefficient.EC that each that will measure according to Sun Yunpei (Y-P Sun) method handled
50Be converted into actual poison exponent (ATI); According to the proportioning of mixture, calculate theoretical poison exponent (TTI), calculate the co-toxicity coefficient (CTC) of mixture by following formula.
Theory is used the content (%) of toxicity index * B in using with of content (the %)+B of toxicity index * A in using with of toxicity index (TTI)=A with
If co-toxicity coefficient is greater than 120, showing has synergistic effect; If be starkly lower than 100, be indicated as antagonism; Between 100~120, be indicated as summation action.
The composite Toxicity Determination result of table 2 thifluzamide and tetraconazole to rice green smut
Can find out that from table 1 and table 2 result thifluzamide and tetraconazole are mixed, in weight ratio is 15: 1~1: 10 scope, banded sclerotial blight and false smut all shown as obvious synergistic effect.The result shows that thifluzamide and tetraconazole are mixed and have reasonability and feasibility.
Field application test 1: prevent and treat the rice sheath blight disease field control effectiveness test
According to the regulation of medicine inspecting institute of the Ministry of Agriculture " GB/T 17980.20-2000 pesticide field efficacy medicine test criterion ()---bactericidal agent for preventing and treating rice sheath blight disease ", the sub-district of test medicine, contrast medicament and blank is handled and is adopted district's group arrangement at random, sub-district area 15m
2, 4 repetitions, this test amounts to twice of dispenser.Be in their early stage during dispenser for the first time, execute medicine for the second time after two weeks.This test is investigated 2 times altogether, and 5 samplings of diagonal are adopted in every experimental plot, and every some investigation links to each other 5 clumps, and totally 25 clumps, record disease grade.
The disease grade scale is following:
0 grade: complete stool is anosis;
1 grade: quaterfoil and following each leaf sheath thereof, blade morbidity (is first leaf with sword-like leave);
3 grades: the 3rd leaf and following each leaf sheath thereof, blade morbidity;
5 grades: second leaf and following each leaf sheath thereof, blade morbidity;
7 grades: sword-like leave blade and following each leaf sheath thereof, blade morbidity;
9 grades: the complete stool morbidity, withered ahead of time.
The drug effect computational methods:
According to investigation result, calculate disease index and preventive effect according to following (1), (2) formula.
In the formula: CK
0, CK
1Be respectively the forward and backward disease index of blank district dispenser; PT
0, PT
1Be respectively the forward and backward disease index of chemicals treatment district medicine.
Table 3 is prevented and treated rice sheath blight disease field control effectiveness test result
Field application test 2: control rice green smut field control effectiveness test
The sub-district of test medicine, contrast medicament and blank is handled and is adopted district's group arrangement at random, sub-district area 20m
2, 4 repetitions, this test amounts to twice of dispenser.Be in their early stage during dispenser for the first time, execute medicine for the second time after 1 week.5 samplings of diagonal are adopted in every experimental plot, and every some investigation links to each other 5 clumps, totally 25 clumps, investigate the infected seed number of each sub-district, record disease grade.
The disease grade scale is following:
0 grade: anosis;
1 grade: 1 granulosis grain;
2 grades: 2~5 granulosis grains;
3 grades: 6~10 granulosis grains;
4 grades: 11~15 granulosis grains;
5 grades: 16 above infected seeds.
The drug effect computational methods:
According to investigation result, calculate disease index and preventive effect according to following (1), (2) formula.
In the formula: CK
0, CK
1Be respectively the forward and backward disease index of blank district dispenser; PT
0, PT
1Be respectively the forward and backward disease index of chemicals treatment district medicine.
Table 4 control rice green smut field control effectiveness test result
Above-mentioned indoor biometrics and field control effectiveness test result show that the beneficial effect that bactericidal composition according to the invention produces is:
(1) compare with single agent, this bactericidal composition has remarkable role in synergy to rice sheath blight disease and false smut, has improved bactericidal effect, and effect is apparently higher than the single bactericide of independent use;
(2) lower drug cost, reduce environmental pollution and residue of pesticide;
(3) composition is made up of the active ingredient of different effects mechanism, and the action site increase helps overcoming and delays the drug-fast generation of germ.The present composition does not all have obvious harmful effect to trial crops, and leaf look, growing way etc. are all normal, and safety is good, meets the security requirement of pesticidal preparations.
Bactericidal composition according to the invention has good preventive effect to rice sheath blight disease and false smut.