CN102204546A - Bactericidal composition containing thifluzamide and triazole compounds - Google Patents
Bactericidal composition containing thifluzamide and triazole compounds Download PDFInfo
- Publication number
- CN102204546A CN102204546A CN2011100957141A CN201110095714A CN102204546A CN 102204546 A CN102204546 A CN 102204546A CN 2011100957141 A CN2011100957141 A CN 2011100957141A CN 201110095714 A CN201110095714 A CN 201110095714A CN 102204546 A CN102204546 A CN 102204546A
- Authority
- CN
- China
- Prior art keywords
- thifluzamide
- bactericidal composition
- disease
- active component
- metconazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a bactericidal composition containing thifluzamide and triazole compounds. The bactericidal composition comprises an active component A and an active component B, wherein the active component A is selected from thifluzamide, and the active component B is selected from one of metconazole, triticonazole, imibenconazole or fenbuconazole; the weight proportion of the effective active component A to the effective active component B is (1-80 percent): (1-80 percent); and an accessory ingredient and an excipient are added into the effective active components to prepare wettable powder, water dispersible granules, a suspending agent, suspended emulsion or a suspension seed coating agent. The bactericidal composition provided by the invention is used for preventing and curing rice blast, banded sclerotial blight, septoria nodorum, a rust disease, powdery mildew, anthracnose, botrytis, downy mildew, alternaria mali Roberts, a rot disease, a tan disease, cladosporium cucumerinum, leaf spot, an epidemic disease, a black rot disease, a brown spot disease, a scab disease and leaf blight and has the effects of less dosage, rain washing resistance and obvious synergia.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest that contains thifluzamide and triazole class compounds.
Technical background
Thifluzamide, English name: thifluzamide, molecular formula: C
13H
6Br
2F
6N
2O
2S, chemical name: 2,6-two bromo-2-methyl-4-trifluoromethoxy-4-Trifluoromethyl-1,3-thiazole-5-carbonyl acyl are for aniline, structural formula:
Thifluzamide belongs to the thiazole amide bactericide, has strong interior conductivity and the long lasting effect of inhaling.Thifluzamide is the succinate dehydrogenase inhibitor, and main effect is the acidohydrogenase that suppresses in the disease fungus tricarbonic acid cycle, causes thalline death.Because fluorine-containing, its its competitiveness in biochemical pathway is very strong, in case combine with regard to difficult recovery with substrate or enzyme.Thifluzamide all has activity to pathomycetes such as Rhizoctonia, Puccinia, Ustilago, Tilletia, corticium, nuclear cavity Pseudomonas, especially the fungus-caused disease of Basidiomycetes such as banded sclerotial blight, damping off etc. is had special efficacy.
Metconazole (metconazole), molecular formula: C
17H
22ClN
3O, chemical name: (1RS, 5RS; 1RS, 5SR)-5-(4-chlorphenyl)-2,2-dimethyl-1-(1-hydrogen-1,2,4-triazole-1-methyl) cyclopentanol, C-14 demethylation enzyme inhibitor in the ergosterol biosynthesis.Though the mechanism of action is the same with other triazole bactericidal agents, activity profile then difference is bigger.Two kinds of isomer all have bactericidal activity, but that the cis activity is higher than is trans.The antifungal spectrum of metconazole is very extensive, and active splendid.The metconazole field is used and cereal septoria musiva, fusarium and handle rest fungus is planted disease remarkable effect is arranged.Metconazole is compared with traditional biocide agent, and dosage is extremely low and prevent and treat cereal to plant the disease scope very wide.
Triticonazole (triticonazole), molecular formula: C
17H
20ClN
3O, chemical name: (±)-(E)-5-(4-benzyl chloride thiazolinyl)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-yl methyl) cyclopentanol, C-14 demethylation enzyme inhibitor in the sterol biosynthesis.Main as seed treatment.
Glyoxalin (imibenconazole), molecular formula: C
17H
13Cl
3N
4S, chemical name: 4-benzyl chloride base N-(2,4 dichloro benzene base)-2 (1H-1,2,4-triazol-1-yl) thioacetamide ester, glyoxalin belongs to the broad spectrum activity triazole bactericidal agent.Mainly be the biosynthesis that destroys and stop the cell membrane important component part ergosterol of germ, thereby destroyed the formation of cell membrane, cause germ death.
RH-7592 (fenbuconazole), molecular formula: C
19H
17ClN
4, chemical name: 4-(4-chlorphenyl)-2-phenyl-2 (1H-1,2,4-triazol-1-yl methyl) butyronitrile belongs to ergosterol biosynthesis inhibitor (EBI).Have protection concurrently, cure the disease and the interior absorption spectrum bactericide of killing action.
In the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the drug-fast generation of germ.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery is composite mutually with thifluzamide and effective active composition B, good synergistic effect is arranged within the specific limits, and relevant composite about thifluzamide and metconazole, triticonazole, glyoxalin, RH-7592, do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains thifluzamide and triazole class compounds.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition that contains thifluzamide is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～80%: 1～80%, and described A component is a thifluzamide, and the B component is selected from a kind of in metconazole, triticonazole, glyoxalin or the RH-7592.
The described bactericidal composition that contains thifluzamide is characterized in that: wherein the percentage by weight of thifluzamide and effective active composition B is 2～60%: 2～60%.
The described bactericidal composition that contains thifluzamide is characterized in that: the percentage by weight of thifluzamide and metconazole is 5～40%: 5～40%.
The described bactericidal composition that contains thifluzamide is characterized in that: the percentage by weight of thifluzamide and triticonazole is 5～40%: 5～40%.
The described bactericidal composition that contains thifluzamide is characterized in that: the percentage by weight of thifluzamide and glyoxalin is 5～40%: 5～50%.
The described bactericidal composition that contains thifluzamide is characterized in that: the percentage by weight of thifluzamide and RH-7592 is 5～40%: 5～40%.
The described bactericidal composition that contains thifluzamide, wherein the effective active component content accounts for 1～90% of gross weight, is preferably 5～80%.
The described bactericidal composition that contains thifluzamide is made wetting powder, water dispersible granules, suspending agent, suspension emulsion or suspension seed-coating agent.
Described bactericidal composition is mainly used in plant diseases such as control rice blast, banded sclerotial blight, glume blight, rust, powdery mildew, anthracnose, spot defoliation, rot, brown spot, scab, leaf spot, leaf blight, gray mold, downy mildew, eqpidemic disease, black spot, brown spot, shot hole.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 1～90% of a gross weight in the composition, and preferable is 5%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～60% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, thickener or the defoamer one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, suspension seed-coating agent.
When making wetting powder, composition comprises following constituent content: thifluzamide 1～80%, active component B1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～91%.
The former medicine of thifluzamide, the former medicine of active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: thifluzamide 1～80%, active component B1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～92%.
The former medicine of thifluzamide, the former medicine of active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the preparation materials.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
When making suspending agent, composition comprises following constituent content: thifluzamide 1～50%, active component B1～50%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, deionized water adds to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned prescription are mixed through high speed shear, add the former medicine of thifluzamide, the former medicine of active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise following constituent content when composition is made suspension emulsion: thifluzamide 1～50%, active component B1～50%, emulsifier 2～10%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned prescription are mixed through high speed shear, add the former medicine of active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make active component B suspending agent, then with the former medicine of thifluzamide, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
When making suspension seed-coating agent, composition comprises following constituent content: thifluzamide 1～40%, active component B1～40%, film forming agent 3～6%, binding agent 2～5%, dispersant 2～10%, wetting agent 2～5%, antifreeze 0.1～8%, defoamer 0.1～2%, thickener 0.1～2%, filler 10～92%.
The former medicine of thifluzamide, active ingredient B in the above-mentioned prescription are mixed, carry out high-speed wet type pulverizing, frosted, add dispersant, binding agent, film forming agent, wetting agent, antifreeze, filler etc. then, mix, make present composition suspension seed-coating agent product through modulation kettle.
Beneficial effect of the present invention: (1) present composition effective active composition thifluzamide and effective active composition B belong to the bactericide of two kinds of different mechanisms of action, and both are mixed mutually and can produce conflict; (2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage; (4) present composition has enlarged fungicidal spectrum, and crop rice blast, banded sclerotial blight, glume blight, rust, powdery mildew, anthracnose, spot defoliation, rot, brown spot, scab, leaf spot, leaf blight, gray mold, downy mildew, eqpidemic disease, black spot, brown spot, shot hole are all had special efficacy.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 1 80% thifluzamide metconazole wetting powder
Thifluzamide 78%, metconazole 2%, aryl phenol polyoxyethylene succinate sulfonate 6%, silkworm excrement 5%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 80% thifluzamide metconazole wetting powder.
Example 2 65% thifluzamide metconazole wetting powders
Thifluzamide 60%, metconazole 5%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 5%, spaonin powder 3%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 65% thifluzamide metconazole wetting powder.
Example 3 64% thifluzamide metconazole water dispersible granules
Thifluzamide 60%, metconazole 4%, polycarboxylate 8%, lauryl sodium sulfate 5%, ammonium sulfate 2%, diatomite add to 100%, the mixed 64% thifluzamide metconazole water dispersible granules that gets.
Example 4 70% thifluzamide metconazole water dispersible granules
Thifluzamide 40%, metconazole 30%, lignosulfonates 7%, neopelex 5%, bentonite add to 100%, the mixed 70% thifluzamide metconazole water dispersible granules that gets.
Example 5 35% thifluzamide metconazole suspending agents
Thifluzamide 15%, metconazole 20%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, silkworm excrement 5%, C10～20 saturated fat acids 1.2%, xanthans 1.5%, propane diols 3%, deionized water add to 100%, the mixed 35% thifluzamide metconazole suspending agent that gets.
Example 6 40% thifluzamide metconazole suspending agents
Thifluzamide 30%, metconazole 10%, the phonetic formaldehyde condensation products sulphate 8% of alkylphenol-polyethenoxy, lauryl sodium sulfate 4%, silicone compound 1.5%, gum Arabic 2.5%, ethylene glycol 3%, deionized water add to 100%, the mixed 40% thifluzamide metconazole suspending agent that gets.
Example 7 45% thifluzamide metconazole suspension emulsions
Thifluzamide 40%, metconazole 5%, naphthalene sulfonic acid-formaldehyde condensation product 6.5%, Nekal BX 6%, silicone compound 1.8%, triphenyl phosphite 2%, polyvinylpyrrolidone 2.2%, Nongru-700 #7%, ethylene glycol 1.5%, water add to 100%, the aforementioned formula material is mixed, promptly make 45% thifluzamide metconazole suspension emulsion.
Example 8 38% thifluzamide metconazole suspension emulsions
Thifluzamide 18%, metconazole 20%, alkylphenol-polyethenoxy are phonetic 4.5%, neopelex 3.5%, silicone oil 0.8%, polyvinylpyrrolidone 1.3%, tween 6%, polyethylene glycol 3%, water add to 100%, the aforementioned formula material is mixed, promptly make 38% thifluzamide metconazole suspension emulsion.
Example 9 25% thifluzamide metconazole suspension seed-coating agents
Thifluzamide 20%, metconazole 5%, fatty alcohol-polyoxyethylene ether 5%, naphthalenesulfonateformaldehyde formaldehyde carboxylic compound 3.5%, polyvinyl acetate 2%, ethylene glycol 5%, dextrin 1.3%, C10～20 saturated fat acids 0.7%, naphthenate 16%, bentonite add to 100%, through the mixed 25% thifluzamide metconazole suspension seed-coating agent that gets.
Example 10 15% thifluzamide metconazole suspension seed-coating agents
Thifluzamide 5%, metconazole 10%, Sodium Polyacrylate 3%, sodium alginate 4.5%, calcium chloride 2%, humus 15%, glycerine 2%, silicone 1.2%, polyvinyl acetate 1.3%, white carbon 10%, kaolin adds to 100%, through the mixed 15% thifluzamide metconazole suspension seed-coating agent that gets.
Example 11 56% thifluzamide triticonazole wetting powders
Thifluzamide 6%, triticonazole 50%, naphthalene sulfonic acid-formaldehyde condensation product 6%, silkworm excrement 5%, starch add to 100%, and mixture carries out comminution by gas stream, make 56% thifluzamide triticonazole wetting powder.
Example 12 78% thifluzamide triticonazole wetting powders
Thifluzamide 70%, triticonazole 8%, polycarboxylate 7%, soapberry powder 4%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 78% thifluzamide triticonazole wetting powder.
Example 13 48% thifluzamide triticonazole water dispersible granules
Thifluzamide 40%, triticonazole 8%, lignosulfonates 7%, lauryl sodium sulfate 6%, sodium bicarbonate 1.5%, kaolin add to 100%, the mixed 48% thifluzamide triticonazole water dispersible granules that gets.
Example 14 65% thifluzamide triticonazole water dispersible granules
Thifluzamide 55%, triticonazole 10%, polyoxyethylene carboxylate 8%, neopelex 5%, bentonite add to 100%, the mixed 65% thifluzamide triticonazole water dispersible granules that gets.
Example 15 25% thifluzamide triticonazole suspending agents
Thifluzamide 15%, triticonazole 10%, aryl phenol polyoxyethylene succinate sulfonate 7%, lauryl sodium sulfate 6%, silicone compound 0.6%, polyvinylpyrrolidone 1.5%, polyethylene glycol 1.2%, deionized water adds to 100%, the mixed 25% thifluzamide triticonazole suspending agent that gets.
Example 16 40% thifluzamide triticonazole suspending agents
Thifluzamide 10%, triticonazole 30%, polycarboxylate 6%, lauryl sodium sulfate 5%, silicone oil 0.4%, gum Arabic 1%, glycerine 1.6%, deionized water adds to 100%, the mixed 40% thifluzamide triticonazole suspending agent that gets.
Example 17 30% thifluzamide triticonazole suspension emulsions
Thifluzamide 20%, triticonazole 10%, polyoxyethylene carboxylate 6%, lauryl sodium sulfate 5%, polyvinylpyrrolidone 1.4%, polyethylene glycol 2%, C10～20 saturated fat acids 0.3%, agricultural newborn 600#7%, water add to 100%, the mixed 30% thifluzamide triticonazole suspension emulsion that gets.
Example 18 20% thifluzamide triticonazole suspension emulsions
Thifluzamide 15%, triticonazole 5%, aryl phenol polyoxyethylene succinate sulfonate 7%, soapberry powder 5%, sodium phosphate trimer 1.2%, ethylene glycol 1.3%, C
10～20Saturated fat acids 0.6%, OP series 6%, water add to 100%, the mixed 20% thifluzamide triticonazole suspension emulsion that gets.
Example 19 10% thifluzamide triticonazole suspension seed-coating agents
Thifluzamide 8%, triticonazole 2%, fatty alcohol-polyoxyethylene ether 5%, naphthalenesulfonateformaldehyde formaldehyde carboxylic compound 3%, polyvinyl acetate 2%, ethylene glycol 5%, dextrin 2.4%, C10～20 saturated fat acids 1.6%, naphthenate 18%, bentonite add to 100%, through the mixed 10% thifluzamide triticonazole suspension seed-coating agent that gets.
Example 20 30% thifluzamide triticonazole suspension seed-coating agents
Thifluzamide 25%, triticonazole 5%, Sodium Polyacrylate 3%, sodium alginate 4.4%, calcium chloride 2%, humus 15%, glycerine 2%, silicone 1.2%, polyvinyl acetate 2.6%, white carbon 10%, kaolin adds to 100%, through the mixed 30% thifluzamide triticonazole suspension seed-coating agent that gets.
Example 21 58% thifluzamide glyoxalin wetting powders
Thifluzamide 26%, glyoxalin 32%, aryl phenol polyoxyethylene succinate sulfonate 6%, Nekal BX 6%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 58% thifluzamide glyoxalin wetting powder.
Example 22 70% thifluzamide glyoxalin wetting powders
Thifluzamide 60%, glyoxalin 10%, naphthalene sulfonic acid-formaldehyde condensation product 8%, lauryl sodium sulfate 6%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 70% thifluzamide glyoxalin wetting powder.
Example 23 56% thifluzamide Imibenconazole water dispersible granules
Thifluzamide 50%, glyoxalin 6%, lignosulfonates 7%, neopelex 6%, urea 1%, attapulgite add to 100%, the mixed 56% thifluzamide Imibenconazole water dispersible granule that gets.
Example 24 72% thifluzamide Imibenconazole water dispersible granules
Thifluzamide 22%, glyoxalin 50%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, lauryl sodium sulfate 5%, bentonite add to 100%, the mixed 72% thifluzamide Imibenconazole water dispersible granule that gets.
Example 25 25% thifluzamide glyoxalin suspending agents
Thifluzamide 20%, glyoxalin 5%, the phonetic formaldehyde condensation products sulphate 7% of alkylphenol-polyethenoxy, lauryl sodium sulfate 4%, silicone compound 0.4%, polyvinylpyrrolidone 1.6%, ethylene glycol 1.5%, deionized water add to 100%, the mixed 25% thifluzamide glyoxalin suspending agent that gets.
Example 26 36% thifluzamide glyoxalin suspending agents
Thifluzamide 6%, glyoxalin 30%, polycarboxylate 6%, soapberry powder 5%, silicone oil 0.3%, gum Arabic 1.2%, glycerine 1.8%, deionized water add to 100%, the mixed 36% thifluzamide glyoxalin suspending agent that gets.
Example 27 24% thifluzamide glyoxalin suspension emulsions
Thifluzamide 18%, glyoxalin 6%, lignosulfonates 6%, lauryl sodium sulfate 5%, C
10～20Saturated fat acids 0.6%, gum Arabic 1.2%, agricultural newborn 600#5%, polyethylene glycol 3%, water add to 100%, and the aforementioned formula material is mixed, and promptly make 24% thifluzamide glyoxalin suspension emulsion.
Example 28 38% thifluzamide glyoxalin suspension emulsions
Thifluzamide 30%, glyoxalin 8%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, soapberry powder 4%, silicone compound 0.5%, sodium phosphate trimer 1.5%, 600# phosphate 6%, propane diols 2%, water add to 100%, the aforementioned formula material is mixed, promptly make 38% thifluzamide glyoxalin suspension emulsion.
Example 29 20% thifluzamide glyoxalin suspension seed-coating agents
Thifluzamide 18%, metconazole 2%, fatty alcohol-polyoxyethylene ether 5%, naphthalenesulfonateformaldehyde formaldehyde carboxylic compound 4%, polyvinyl acetate 2%, ethylene glycol 3%, dextrin 1.2%, C10～20 saturated fat acids 0.8%, naphthenate 22%, bentonite add to 100%, through the mixed 20% thifluzamide glyoxalin suspension seed-coating agent that gets.
Example 30 10% thifluzamide glyoxalin suspension seed-coating agents
Thifluzamide 5%, glyoxalin 5%, Sodium Polyacrylate 3%, sodium alginate 4.2%, calcium chloride 2%, humus 20%, glycerine 2%, silicone 2.2%, polyvinyl acetate 3.6%, white carbon 10%, kaolin adds to 100%, through the mixed 10% thifluzamide glyoxalin suspension seed-coating agent that gets.
Example 31 50% thifluzamide RH-7592 wetting powders
Thifluzamide 5%, RH-7592 45%, naphthalene sulfonic acid-formaldehyde condensation product 6%, soapberry powder 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 50% thifluzamide RH-7592 wetting powder.
Example 32 70% thifluzamide RH-7592 wetting powders
Thifluzamide 10%, RH-7592 60%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, Nekal BX 4%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 70% thifluzamide RH-7592 wetting powder.
Example 33 56% thifluzamide RH-7592 water dispersible granules
Thifluzamide 50%, RH-7592 6%, lauryl sodium sulfate 5%, lignosulfonates 5%, ammonium sulfate 1.5%, kaolin add to 100%, the mixed 56% thifluzamide RH-7592 water dispersible granules that gets.
Example 34 67% thifluzamide RH-7592 water dispersible granules
Thifluzamide 45%, RH-7592 22%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, soapberry powder 6%, bentonite add to 100%, the mixed 67% thifluzamide RH-7592 water dispersible granules that gets.
Example 35 27% thifluzamide RH-7592 suspending agents
Thifluzamide 18%, RH-7592 9%, polycarboxylate 6%, spaonin powder 4%, silicone oil 0.2%, xanthans 1.2%, ethylene glycol 1.8%, deionized water add to 100%, the mixed 27% thifluzamide RH-7592 suspending agent that gets.
Example 36 45% thifluzamide RH-7592 suspending agents
Thifluzamide 30%, RH-7592 15%, naphthalene sulfonic acid-formaldehyde condensation product 6%, lauryl sodium sulfate 5%, C
10～20Saturated fat acids 0.2%, sodium phosphate trimer 1.4%, glycerine 2%, deionized water add to 100%, the mixed 45% thifluzamide RH-7592 suspending agent that gets.
Example 37 30% thifluzamide RH-7592 suspension emulsions
Thifluzamide 20%, RH-7592 10%, lignosulfonates 5%, lauryl sodium sulfate 5%, silicone compound 0.4%, polyvinylpyrrolidone 1.6%, 600# phosphate 6%, polyethylene glycol 3%, water add to 100%, the aforementioned formula material is mixed, promptly make 30% thifluzamide RH-7592 suspension emulsion.
Example 38 48% thifluzamide RH-7592 suspension emulsions
Thifluzamide 40%, RH-7592 8%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, soapberry powder 6%, silicone compound 0.2%, gum Arabic 1.5%, OP series 6%, ethylene glycol 2%, water add to 100%, the aforementioned formula material is mixed, promptly make 48% thifluzamide RH-7592 suspension emulsion.
Example 39 20% thifluzamide RH-7592 suspension seed-coating agents
Thifluzamide 10%, RH-7592 10%, fatty alcohol-polyoxyethylene ether 5%, naphthalenesulfonateformaldehyde formaldehyde carboxylic compound 4.4%, polyvinyl acetate 2%, ethylene glycol 3%, dextrin 2.6%, C10～20 saturated fat acids 1.5%, naphthenate 27%, bentonite add to 100%, through the mixed 20% thifluzamide RH-7592 suspension seed-coating agent that gets.
Example 40 10% thifluzamide RH-7592 suspension seed-coating agents
Thifluzamide 5%, RH-7592 5%, Sodium Polyacrylate 3%, sodium alginate 3.2%, calcium chloride 2.2%, humus 12%, glycerine 2%, silicone 1.6%, polyvinyl acetate 3.6%, white carbon 10%, kaolin adds to 100%, through the mixed 10% thifluzamide RH-7592 suspension seed-coating agent that gets.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Suspension seed-coating agent the key technical indexes of the present invention:
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Thifluzamide and active component B (B be selected from metconazole, triticonazole, glyoxalin, the RH-7592 a kind of) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component thifluzamide and active component B (metconazole, triticonazole, glyoxalin, RH-7592) shared ratio in combination;
A is a thifluzamide;
B is a kind of in metconazole, triticonazole, glyoxalin, the RH-7592.
Implementation of an application example two:
Thifluzamide and metconazole are composite to the wheat powdery mildew Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining thifluzamide, the former medicine of metconazole and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 thifluzamide, metconazole and composite toxicity test analysis of results table thereof to wheat powdery mildew
As shown in Table 1, thifluzamide, metconazole are to the EC of wheat powdery mildew
50Be respectively 0.88mg/L and 0.75mg/L.Thifluzamide and metconazole proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that thifluzamide and metconazole were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, wherein synergistic effect is the most remarkable when thifluzamide and metconazole proportioning are 20: 1 to 1: 20, especially when the proportioning of thifluzamide and metconazole during at 4: 1 to 1: 4, synergy ratio SR maximum, synergistic effect is the most obvious.
Implementation of an application example three
Thifluzamide and triticonazole are composite to the cucumber anthracnose Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining thifluzamide, the former medicine of triticonazole and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 thifluzamide, triticonazole and composite toxicity test analysis of results table thereof to bitter rot or anthracnose of grape
As shown in Table 2, thifluzamide, triticonazole are to the EC of cucumber anthracnose
50Be respectively 0.89mg/L and 0.76mg/L.Thifluzamide and triticonazole proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that thifluzamide and triticonazole were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, wherein synergistic effect is the most remarkable when thifluzamide and triticonazole proportioning are 20: 1 to 1: 20, especially when the proportioning of thifluzamide and triticonazole during at 4: 1 to 1: 4, synergy ratio SR maximum, synergistic effect is the most obvious.
Implementation of an application example four
Thifluzamide and glyoxalin are composite to the rice sheath blight disease Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining thifluzamide, the former medicine of glyoxalin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 thifluzamide, glyoxalin and composite toxicity test analysis of results table thereof to pear scab
As shown in Table 3, thifluzamide, glyoxalin are to the EC of pear scab
50Be respectively 0.66mg/L and 0.85mg/L.Thifluzamide and glyoxalin proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that thifluzamide and glyoxalin were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, wherein synergistic effect is the most remarkable when thifluzamide and glyoxalin proportioning are 20: 1 to 1: 20, especially when the proportioning of thifluzamide and glyoxalin during at 4: 1 to 1: 4, synergy ratio SR maximum, synergistic effect is the most obvious.
Implementation of an application example five
Thifluzamide and RH-7592 are composite to the rice sheath blight disease Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining thifluzamide, the former medicine of RH-7592 and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 4 thifluzamide, RH-7592 and composite toxicity test analysis of results table thereof to rice sheath blight disease
As shown in Table 4, thifluzamide, RH-7592 are to the EC of rice sheath blight disease
50Be respectively 0.69mg/L and 0.76mg/L.Thifluzamide and RH-7592 proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that thifluzamide and RH-7592 were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, wherein synergistic effect is the most remarkable when thifluzamide and RH-7592 proportioning are 20: 1 to 1: 20, especially when the proportioning of thifluzamide and RH-7592 during at 4: 1 to 1: 4, synergy ratio SR maximum, synergistic effect is the most obvious.
The composite seed dressing control of Application Example six thifluzamides and the triazole class compounds wheat diseases test of pesticide effectiveness
This experimental establishment is in suburb, Xinxiang City, Henan Province, test medicine is researched and developed, is provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 240g/L thifluzamide suspending agent (commercial), 5% metconazole seed treatment emulsion (commercial), 25 grams per liter triticonazole suspension seed-coating agents (commercial), 25 grams per liter glyoxalin suspension seed-coating agents (commercial), 5% RH-7592 seed dressing (commercial).
The local wheat state of an illness of investigation is mixed seed dressing 1 minute with the seed jolting in closed container before the sowing before the medicine, again with planting seed to the experimental field, and laggard pedestrian worker's irrigation in one day.Investigate disease index respectively in 30 days, 50 days after the dispenser and calculate preventive effect.
Experimental result is as follows:
The composite seed dressing control of table 5 thifluzamide and the triazole class compounds wheat diseases test of pesticide effectiveness
As can be seen from Table 5, can effectively prevent and treat wheat diseases after thifluzamide and triazole class compounds are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase reached more than 50 days.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven thifluzamides and metconazole and the composite control wheat powdery mildew test of pesticide effectiveness thereof
This experimental establishment is in Deyang City suburb, Sichuan Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 240g/L thifluzamide suspending agent (commercial), 60 grams per liter metconazole aqueous emulsions (commercial).
The investigation wheat powdery mildew state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 6 thifluzamide, metconazole and the composite control wheat powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 6, can effectively prevent and treat wheat powdery mildew after thifluzamide and metconazole are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
The sick test of pesticide effectiveness of Application Example eight thifluzamides and triticonazole and composite control alternaria leaf spot of apple thereof
This experimental establishment is in suburb, Liquan County, Shaanxi Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 240g/L thifluzamide suspending agent (commercial), 25 grams per liter triticonazole suspending agents (commercial).
The sick disease index of the preceding investigation of medicine alternaria leaf spot of apple, in the their early stage dispenser, every dispenser on the 7th once, dispenser is 3 times altogether, investigates disease indexs in 3 days, 14 days, 30 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 7 thifluzamide, the sick test of pesticide effectiveness of the composite control alternaria leaf spot of apple of triticonazole
As can be seen from Table 7, can effectively prevent and treat the alternaria leaf spot of apple disease after thifluzamide and triticonazole are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine thifluzamides and glyoxalin and the composite rice sheath blight disease of preventing and treating thereof are imitated test
This experimental establishment is in suburb, Guangxi province Liuzhou City, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 240g/L thifluzamide suspending agent (commercial), 10% glyoxalin suspending agent (commercial).
The preceding investigation of medicine rice sheath blight disease disease index, in the their early stage dispenser, dispenser for the second time after 7 days, dispenser is 2 times altogether, investigates disease indexs in 3 days, 14 days, 30 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 8 thifluzamide, glyoxalin and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 8, can effectively prevent and treat rice sheath blight disease after thifluzamide and glyoxalin are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten thifluzamides and RH-7592 and the composite sigatoka test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in river mouth, Yunnan Province county, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 240g/L thifluzamide suspending agent (commercial), 24% RH-7592 missible oil (commercial).
The investigation sigatoka state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 3 times.Investigated disease index respectively and calculated preventive effect in 3 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 9 thifluzamide, RH-7592 and the composite sigatoka test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 9, can effectively prevent and treat sigatoka after thifluzamide and RH-7592 are composite, control efficiency all is better than the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Claims (9)
1. bactericidal composition that contains thifluzamide and triazole class compounds, it is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～80%: 1～80%, described active component A is a thifluzamide, and active component B is selected from a kind of in metconazole, triticonazole, glyoxalin or the RH-7592.
2. bactericidal composition according to claim 1 is characterized in that: wherein the percentage by weight of A, two kinds of active components of B is 2～60%: 2～60%.
3. bactericidal composition according to claim 2 is characterized in that: the percentage by weight of thifluzamide and metconazole is 5～40%: 5～40%.
4. bactericidal composition according to claim 2 is characterized in that: the percentage by weight of thifluzamide and triticonazole is 5～40%: 5～40%.
5. bactericidal composition according to claim 2 is characterized in that: the percentage by weight of thifluzamide and glyoxalin is 5～40%: 5～50%.
6. bactericidal composition according to claim 2 is characterized in that: the percentage by weight of thifluzamide and RH-7592 is 5～40%: 5～40%.
7. bactericidal composition according to claim 1 is characterized in that: microbicide compositions is made wetting powder, water dispersible granules, suspending agent, suspension emulsion or suspension seed-coating agent.
8. bactericidal composition according to claim 1 is used to prevent and treat the disease on grass family class crop, vegetables, ornamental flower and the fruit tree.
9. bactericidal composition according to claim 8 is used to prevent and treat the application of rice blast, banded sclerotial blight, glume blight, rust, powdery mildew, anthracnose, spot defoliation, rot, brown spot, scab, leaf spot, leaf blight, gray mold, downy mildew, eqpidemic disease, black spot, brown spot, shot hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110095714.1A CN102204546B (en) | 2011-04-16 | 2011-04-16 | Bactericidal composition containing thifluzamide and triazole compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110095714.1A CN102204546B (en) | 2011-04-16 | 2011-04-16 | Bactericidal composition containing thifluzamide and triazole compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102204546A true CN102204546A (en) | 2011-10-05 |
| CN102204546B CN102204546B (en) | 2014-02-05 |
Family
ID=44693822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110095714.1A Expired - Fee Related CN102204546B (en) | 2011-04-16 | 2011-04-16 | Bactericidal composition containing thifluzamide and triazole compounds |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102204546B (en) |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379293A (en) * | 2011-10-26 | 2012-03-21 | 广东中迅农科股份有限公司 | Bactericidal composition |
| CN102405915A (en) * | 2011-11-17 | 2012-04-11 | 湖南农大海特农化有限公司 | Bactericidal composition containing thifluzamide and myclobutanil and application thereof |
| CN102613206A (en) * | 2012-03-19 | 2012-08-01 | 王春水 | Agricultural bactericide containing thifluzamide and application of agricultural bactericide |
| CN102626089A (en) * | 2012-03-19 | 2012-08-08 | 王春水 | Agricultural sterilization composition containing thifluzamide and use thereof |
| CN102657185A (en) * | 2012-04-20 | 2012-09-12 | 杭州宇龙化工有限公司 | Sterilization combination containing thifluzamide and tetraconazole |
| CN102657183A (en) * | 2012-04-12 | 2012-09-12 | 广西田园生化股份有限公司 | Thifluzamide-containing ultra low volume liquid formulation |
| CN102657186A (en) * | 2012-04-24 | 2012-09-12 | 杭州宇龙化工有限公司 | Bactericidal composition containing thifluzamide and prothioconazole |
| CN103004806A (en) * | 2012-12-11 | 2013-04-03 | 青岛东生药业有限公司 | Seed treating agent and preparing method thereof |
| CN103004810A (en) * | 2012-12-11 | 2013-04-03 | 青岛东生药业有限公司 | Seed treatment dispersible powder and preparing method thereof |
| CN103392711A (en) * | 2013-08-21 | 2013-11-20 | 陕西康禾立丰生物科技药业有限公司 | Thifluzamide composition for preventing and treating rice diseases, and preparation of thifluzamide composition |
| CN103563919A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and triadimefon and application thereof |
| CN103563913A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and prothioconazole and application thereof |
| CN103563921A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and flutriafol and application thereof |
| CN103563915A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and metconazole and application thereof |
| CN104206394A (en) * | 2012-07-12 | 2014-12-17 | 陕西美邦农药有限公司 | Bactericidal composition containing triadimefon |
| CN114391547A (en) * | 2022-01-19 | 2022-04-26 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Seed coating formula for preventing and controlling soybean southern blight and verticillium wilt |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000608A2 (en) * | 2000-06-12 | 2002-01-03 | Basf Aktiengesellschaft | A process for the preparation of 2,2-dimethyl-5-(4-chlorobenzyl) cyclopentanone and an intermediate useful therefor |
| CN101828559A (en) * | 2010-06-02 | 2010-09-15 | 陕西上格之路生物科学有限公司 | Agricultural sterilizing composite containing thifluzamide |
| CN101878765A (en) * | 2010-07-02 | 2010-11-10 | 惠州市中迅化工有限公司 | Pesticide composition containing thifluzamide and difenoconazole and application thereof |
-
2011
- 2011-04-16 CN CN201110095714.1A patent/CN102204546B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000608A2 (en) * | 2000-06-12 | 2002-01-03 | Basf Aktiengesellschaft | A process for the preparation of 2,2-dimethyl-5-(4-chlorobenzyl) cyclopentanone and an intermediate useful therefor |
| CN101828559A (en) * | 2010-06-02 | 2010-09-15 | 陕西上格之路生物科学有限公司 | Agricultural sterilizing composite containing thifluzamide |
| CN101878765A (en) * | 2010-07-02 | 2010-11-10 | 惠州市中迅化工有限公司 | Pesticide composition containing thifluzamide and difenoconazole and application thereof |
Non-Patent Citations (4)
| Title |
|---|
| 《大麦与谷类科学》 20090625 陈明亮 "24%噻呋酰胺悬浮剂（满穗）防治水稻纹枯病的田间效果" 第52-53页 1-9 , 第2期 * |
| 《现代农业科技》 20071210 汤峰 "24%满穗等几种新型杀菌剂防治水稻纹枯病对比试验" 第85页 1-9 , 第23期 * |
| 汤峰: ""24%满穗等几种新型杀菌剂防治水稻纹枯病对比试验"", 《现代农业科技》, no. 23, 10 December 2007 (2007-12-10), pages 85 * |
| 陈明亮: ""24%噻呋酰胺悬浮剂（满穗）防治水稻纹枯病的田间效果"", 《大麦与谷类科学》, no. 2, 25 June 2009 (2009-06-25), pages 52 - 53 * |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379293B (en) * | 2011-10-26 | 2013-05-08 | 广东中迅农科股份有限公司 | Bactericidal composition |
| CN102379293A (en) * | 2011-10-26 | 2012-03-21 | 广东中迅农科股份有限公司 | Bactericidal composition |
| CN102405915A (en) * | 2011-11-17 | 2012-04-11 | 湖南农大海特农化有限公司 | Bactericidal composition containing thifluzamide and myclobutanil and application thereof |
| CN102405915B (en) * | 2011-11-17 | 2015-10-21 | 湖南农大海特农化有限公司 | A kind of bactericidal composition and application thereof containing thifluzamide and nitrile bacterium azoles |
| CN102613206A (en) * | 2012-03-19 | 2012-08-01 | 王春水 | Agricultural bactericide containing thifluzamide and application of agricultural bactericide |
| CN102626089A (en) * | 2012-03-19 | 2012-08-08 | 王春水 | Agricultural sterilization composition containing thifluzamide and use thereof |
| CN102657183A (en) * | 2012-04-12 | 2012-09-12 | 广西田园生化股份有限公司 | Thifluzamide-containing ultra low volume liquid formulation |
| CN102657185A (en) * | 2012-04-20 | 2012-09-12 | 杭州宇龙化工有限公司 | Sterilization combination containing thifluzamide and tetraconazole |
| CN102657186A (en) * | 2012-04-24 | 2012-09-12 | 杭州宇龙化工有限公司 | Bactericidal composition containing thifluzamide and prothioconazole |
| CN104206394A (en) * | 2012-07-12 | 2014-12-17 | 陕西美邦农药有限公司 | Bactericidal composition containing triadimefon |
| CN103563919A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and triadimefon and application thereof |
| CN103563913A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and prothioconazole and application thereof |
| CN103563921A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and flutriafol and application thereof |
| CN103563915A (en) * | 2012-08-04 | 2014-02-12 | 南京华洲药业有限公司 | Bactericidal composition containing thifluzamide and metconazole and application thereof |
| CN103563913B (en) * | 2012-08-04 | 2015-11-04 | 南京华洲药业有限公司 | A kind of bactericidal composition and application thereof containing thifluzamide and prothioconazoles |
| CN103563921B (en) * | 2012-08-04 | 2015-11-18 | 南京华洲药业有限公司 | A kind of bactericidal composition and application thereof containing thifluzamide and Flutriafol |
| CN103004810A (en) * | 2012-12-11 | 2013-04-03 | 青岛东生药业有限公司 | Seed treatment dispersible powder and preparing method thereof |
| CN103004806A (en) * | 2012-12-11 | 2013-04-03 | 青岛东生药业有限公司 | Seed treating agent and preparing method thereof |
| CN103392711A (en) * | 2013-08-21 | 2013-11-20 | 陕西康禾立丰生物科技药业有限公司 | Thifluzamide composition for preventing and treating rice diseases, and preparation of thifluzamide composition |
| CN114391547A (en) * | 2022-01-19 | 2022-04-26 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Seed coating formula for preventing and controlling soybean southern blight and verticillium wilt |
| CN114391547B (en) * | 2022-01-19 | 2024-04-09 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Seed coating formulation for preventing and controlling soybean southern blight and bacterial wilt |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102204546B (en) | 2014-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102204546B (en) | Bactericidal composition containing thifluzamide and triazole compounds | |
| CN102258043A (en) | Germicide composition containing protioconazole | |
| CN102217604B (en) | Bactericidal composition containing boscalid and triazole compounds | |
| CN103250717A (en) | Bactericidal composition containing procymidone | |
| CN103416428A (en) | Fluxapyroxad-containing sterilization composition | |
| CN102239855A (en) | Bactericidal composition containing trifloxystrobin and triazole | |
| CN102210310B (en) | Sterilizing composite containing famoxadone and triazole compound | |
| CN104336048A (en) | Bactericidal composition containing fluorothiazolepyrithylone and triazoles | |
| CN102273462A (en) | Novel pesticide composition containing prothioconazole and triazoles | |
| CN102217605A (en) | Sterilizing composition containing flutolanil and triazole compound | |
| CN102204542A (en) | Bactericidal composition containing enostroburin and triazole compound | |
| CN103053538A (en) | Fungicide composition | |
| CN102113489B (en) | Bactericidal composition containing metconazole | |
| CN102415389A (en) | Bactericidal composition containing chlorothalonil and triazole compound | |
| CN103749499A (en) | Prothioconazole-containing sterilization composition | |
| CN104285954A (en) | Efficient fungicidal composition | |
| CN102204540B (en) | Sterilization composite containing ethirimol and triazole compound | |
| CN103518741A (en) | Fluopyram-containing high-efficiency bactericidal composition | |
| CN103947650A (en) | Bactericidal composition containing trifloxystrobin and difenoconazole and application of bactericidal composition | |
| CN102090411A (en) | Sterilization composition containing iprodione and triazole compound | |
| CN104012536B (en) | A kind of bactericidal composition of fluorine-containing mepanipyrim and methoxy acrylic | |
| CN102342287A (en) | Sterilization composition containing fluopicolide and polyoxin | |
| CN102302031A (en) | Bactericidal composition containing spiroxamine | |
| CN103535362A (en) | Efficient bactericidal composition | |
| CN102177895B (en) | Antibacterial composition containing cyprodinil |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 715500 middle section of North Ring Road, Pucheng County, Shaanxi Applicant after: Shanxi Thompson Biological Technology Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Applicant before: Shanxi Thompson Biological Technology Co., Ltd. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140205 Termination date: 20160416 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |