CN103416428A - Fluxapyroxad-containing sterilization composition - Google Patents
Fluxapyroxad-containing sterilization composition Download PDFInfo
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- CN103416428A CN103416428A CN2012101674708A CN201210167470A CN103416428A CN 103416428 A CN103416428 A CN 103416428A CN 2012101674708 A CN2012101674708 A CN 2012101674708A CN 201210167470 A CN201210167470 A CN 201210167470A CN 103416428 A CN103416428 A CN 103416428A
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- Prior art keywords
- acid amides
- azoles bacterium
- bacterium acid
- fluorine
- active component
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- 239000000203 mixture Substances 0.000 title claims abstract description 43
- 239000005788 Fluxapyroxad Substances 0.000 title abstract description 4
- SXSGXWCSHSVPGB-UHFFFAOYSA-N fluxapyroxad Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1=CC(F)=C(F)C(F)=C1 SXSGXWCSHSVPGB-UHFFFAOYSA-N 0.000 title abstract description 4
- 230000001954 sterilising effect Effects 0.000 title abstract 4
- 238000004659 sterilization and disinfection Methods 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 57
- 201000010099 disease Diseases 0.000 claims abstract description 56
- OIPMQULDKWSNGX-UHFFFAOYSA-N bis[[ethoxy(oxo)phosphaniumyl]oxy]alumanyloxy-ethoxy-oxophosphanium Chemical compound [Al+3].CCO[P+]([O-])=O.CCO[P+]([O-])=O.CCO[P+]([O-])=O OIPMQULDKWSNGX-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000005764 Dithianon Substances 0.000 claims abstract description 24
- PYZSVQVRHDXQSL-UHFFFAOYSA-N dithianon Chemical compound S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O PYZSVQVRHDXQSL-UHFFFAOYSA-N 0.000 claims abstract description 24
- LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 claims abstract description 23
- 239000005745 Captan Substances 0.000 claims abstract description 23
- 229940117949 captan Drugs 0.000 claims abstract description 23
- 241000894006 Bacteria Species 0.000 claims description 95
- 150000001408 amides Chemical class 0.000 claims description 95
- WHDHEVMINMZADQ-UHFFFAOYSA-N [F].N1C=CC=C1 Chemical class [F].N1C=CC=C1 WHDHEVMINMZADQ-UHFFFAOYSA-N 0.000 claims description 81
- 239000000843 powder Substances 0.000 claims description 34
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- 239000000375 suspending agent Substances 0.000 claims description 30
- 241000233679 Peronosporaceae Species 0.000 claims description 23
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- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 22
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- 206010039509 Scab Diseases 0.000 claims description 13
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- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 6
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 125000001153 fluoro group Chemical group F* 0.000 claims description 5
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- 238000001228 spectrum Methods 0.000 abstract description 2
- CRQQGFGUEAVUIL-UHFFFAOYSA-N chlorothalonil Chemical compound ClC1=C(Cl)C(C#N)=C(Cl)C(C#N)=C1Cl CRQQGFGUEAVUIL-UHFFFAOYSA-N 0.000 abstract 1
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- 239000000575 pesticide Substances 0.000 description 14
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- 229920002521 macromolecule Polymers 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
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- 235000006008 Brassica napus var napus Nutrition 0.000 description 4
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- 241000198596 Alternaria tomatophila Species 0.000 description 3
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- 230000009471 action Effects 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
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- YBNQFFSHDBUNAA-UHFFFAOYSA-N 2,3,4-trifluoro-1h-pyrrole Chemical class FC1=CNC(F)=C1F YBNQFFSHDBUNAA-UHFFFAOYSA-N 0.000 description 1
- UXPRZZZNGFVXRR-UHFFFAOYSA-N 2,3-difluoro-1h-pyrrole Chemical class FC=1C=CNC=1F UXPRZZZNGFVXRR-UHFFFAOYSA-N 0.000 description 1
- 208000031968 Cadaver Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
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- 241000233654 Oomycetes Species 0.000 description 1
- KWYHKXQDUHJSGC-UHFFFAOYSA-N S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O.S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O Chemical compound S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O.S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O KWYHKXQDUHJSGC-UHFFFAOYSA-N 0.000 description 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a fluxapyroxad-containing sterilization composition. The sterilization composition contains an active component A and an active component B, the active component A is selected from fluxapyroxad, the active component B is selected from anyone of active ester, dithianon, fosetyl-aluminum, chlorothalonil and captan, and the weight ratio of the active component A to the active component B is 1:80-60:1. The composition has a high activity against a plurality of diseases on a plurality of crops, has an obvious synergistic effect, enlarges the sterilization spectrum, and has the characteristics of small drug dose, rain wash resistance and obvious synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on corps diseases of fluorine-containing azoles bacterium acid amides.
Technical background
Fluorine azoles bacterium acid amides (Fluxapyroxad) chemical name: the 3-(difluoro)-1-methyl-N-(3', 4', 5'-trifluoro [1,1'-biphenyl]-2-yl)-1-H-pyrazoles-4-acid amides, belong to the pyrazole amide series bactericidal agent, succinate dehydrogenase inhibitors.Superior lasting effect and lasting transmission characteristic are integrated in one.
Dithianon (dithianon) chemical name: 2,3-dinitrile-Isosorbide-5-Nitrae-anthraquinone dithio, molecular formula: C
14H
4N
2O
2S
2.Dithianon has multiaction mechanism, by reacting with sulfur-containing group with interference cell, breathes and suppresses a series of fungal enzymes, finally causes disease death.When thering is good prolection, certain therapeutic activity is also arranged.
Phosethyl-Al (fosetyl-aluminium) chemical name: three-(ethylphosphonic acid) aluminium, molecular formula: C
6H
18AlO
9P
3.Phosethyl-Al is a kind of systemic fungicide to disease tool special efficacy due to oomycetes.Can absorb backward upper transporting by root and base portion cauline leaf, also can absorb backward radical leaves transporting from upper blade.Medicament is competence exertion prophylaxis effect in the plant body only, and in vitro is very little to the inhibitory action of germ, and its diseases prevention principle thinks that medicament stimulates the system of defense of host plant and diseases prevention.
In the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the generation of disease drug resistance.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery is mutually composite by fluorine azoles bacterium acid amides and Acibenzolar, dithianon, phosethyl-Al, tpn, captan, good synergistic effect is arranged within the specific limits, and relevant composite about fluorine azoles bacterium acid amides and Acibenzolar, dithianon, phosethyl-Al, tpn, captan, there is not yet at present relevant report at home and abroad.
Summary of the invention
The objective of the invention is to propose a kind of bactericidal composition with synergistic function, use cost is low, preventive effect is good fluorine-containing azoles bacterium acid amides.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition of fluorine-containing azoles bacterium acid amides, contain active components A and active component B, active components A and active component B weight ratio are 1: 80～60: 1, described active components A is selected from fluorine azoles bacterium acid amides, and active component B is selected from a kind of in Acibenzolar, dithianon, phosethyl-Al, tpn, captan.The preferred weight ratio of active components A and active component B is 1 ︰ 60 ~ 50 ︰ 1; More preferably the weight ratio of fluorine azoles bacterium acid amides and Acibenzolar is 1: 5～30: 1; The weight ratio of fluorine azoles bacterium acid amides and dithianon is 1: 45～5: 1; The weight ratio of fluorine azoles bacterium acid amides and phosethyl-Al is 1: 40～5: 1; The weight ratio of fluorine azoles bacterium acid amides and tpn is 1: 35～5: 1; The weight ratio of fluorine azoles bacterium acid amides and captan is 1 ︰ 40 ~ 8 ︰ 1.
The bactericidal composition of described fluorine-containing azoles bacterium acid amides, can be made into wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
The disease of the bactericidal composition of described fluorine-containing azoles bacterium acid amides for preventing and treating crop, described crop comprises fruit tree, vegetables, cereal crops, ornamental plants, fiber crop.
Described disease comprises downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, resin disease.
Amount of application when in bactericidal composition of the present invention, the content of active component depends on independent use, also depend on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target disease.Usually in composition, the weight percentage of active component is gross weight 1%～90%, is preferably 5%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～60% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
At least contain a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water while being beneficial to use.Surface-active contents is 2%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, thickener or defoamer.According to different dosage form, in preparation, can also contain stabilizing agent known in those skilled in the art, antifreeze etc.
The bactericidal composition of invention can be by the user before use through dilution or directly use.Its preparation can be by processing method known in those skilled in the art preparation, is about to active component and after liquid flux or solid carrier mix, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
When making wetting powder, composition comprises following component and content: active components A 0.5% ~ 60%, active component B 0.5% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
When making water dispersible granules, composition comprises following component and content: active components A 0.5% ~ 60%, active component B 0.5% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Comprise following component and content when composition is made suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is made aqueous emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Comprise following component and content when composition is made microemulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Comprise following component and content when composition is made suspension emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
When making microcapsule suspending agent, composition comprises following component and content: active components A
0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content while making microcapsule suspension-suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension of the present invention-suspending agent the key technical indexes:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) the agricultural chemicals dosage reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) enlarged fungicidal spectrum, multiple diseases has been had to greater activity as downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, resin disease.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment all is weight percentage, but the present invention is not limited thereto.
Application Example one
Example 1 ~ 14 wetting powder
Fluorine azoles bacterium acid amides, active component B, dispersant, wetting agent, filler are mixed, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, can be made into wetting powder product of the present invention.Specifically in Table 1,2.
Table 1 example 1 ~ 7 component and content
Example 15 ~ 28 water dispersible granules
Fluorine azoles bacterium acid amides, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needed through air-flow crushing together, then add other auxiliary agent such as binding agent (can add and can not add), obtain the materials of granulating.By item quantitatively send in the fluidized bed granulation dryer through granulation and drying after, can make water dispersible granules product of the present invention, specifically in Table 3,4.
Table 3 example 15 ~ 21 each component and content
Table 4 example 22 ~ 28 each component and content
Example 29 ~ 42 suspending agents
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), through high speed shear, mix, add fluorine azoles bacterium acid amides, active component B, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, surplus is supplied by deionized water, can make suspending agent product of the present invention, specifically in Table 5,6.
Table 5 example 29 ~ 35 each component and content
Table 6 example 36 ~ 42 each component and content
Example 43 ~ 49 aqueous emulsions
Fluorine azoles bacterium acid amides, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added to oil phase, make aqueous emulsion product of the present invention.Specifically in Table 7.
Table 7 example 43 ~ 49 each component and content
Example 50 ~ 56 microemulsions
Fluorine azoles bacterium acid amides, active component B are dissolved in the homogenizer that solvent is housed, by emulsifier, antifreeze (can add and can not add), defoamer, join in the homogenizer that above-mentioned solution is housed, surplus gives strong the mixing and homogenize after supplying by deionized water, finally obtain the as clear as crystal microemulsion product of the present invention of outward appearance.Specifically in Table 8.
Table 8 example 50 ~ 56 each component and content
Example 57 ~ 61 suspension emulsions
To in fluorine azoles bacterium acid amides, add dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) to mix through high speed shear, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make fluorine azoles bacterium acid amides suspending agent, then by active component B, emulsifier, solvent and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.Specifically in Table 9.
Table 9 example 57 ~ 61 each component and content
Example 62 ~ 68 microcapsule suspending agents
By fluorine azoles bacterium acid amides, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, defoamer, surplus is supplied by deionized water, bi-material reacts at oil-water interfaces, forms the macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 10.
Table 10 example 62 ~ 68 each component and content
Example 69 ~ 75 microcapsule suspensions-suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine azoles bacterium acid amides, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, makes the finely disseminated microcapsule suspension of the present composition-suspending agent product.Specifically in Table 11.
Table 11 example 69 ~ 75 each component and content
Acibenzolar in 1-11, dithianon, phosethyl-Al, tpn, captan exchange will be shown, novel formulation can be made.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect, on this basis, then carry out field trial.
Test method: after the effective inhibition concentration scope of each medicament is determined in prerun, medicament is established respectively 5 dosage by active constituent content and is processed, and establishes the clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament to the crop germ.Measure colony diameter by the right-angled intersection method after 72h, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into to probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50Value.Calculate the different proportioning synergy ratio (SR) of two medicaments according to the Wadley method, SR<0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is fluorine azoles bacterium acid amides; B is selected from a kind of in Acibenzolar, dithianon, tpn, phosethyl-Al, captan.
Application Example two:
For trying disease: graw mold of tomato; Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd.; Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the two different proportioning mixture of Acibenzolar through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to graw mold of tomato of table 12 fluorine azoles bacterium acid amides and Acibenzolar
As shown in Table 12, the proportioning of fluorine azoles bacterium acid amides and the composite control graw mold of tomato of Acibenzolar is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, the proportioning of fluorine azoles bacterium acid amides and Acibenzolar was at 1: 5～30: 1, and synergistic effect is more outstanding; Synergy ratio maximum when fluorine azoles bacterium acid amides and Acibenzolar weight ratio are 6:1, synergistic effect is the most obvious.Testing through the applicant proportioning of finding fluorine azoles bacterium acid amides and Acibenzolar is 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 11:1, 12:1, 13:1, 14:1, 15:1, 20:1, 25:1, during 30:1 to downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, the control of resin disease has obvious synergistic effect, synergy ratio is all more than 2.10.
Application Example three:
For trying disease: downy mildew of garpe
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of dithianon and the two different proportioning mixture through preliminary experiment
The toxicity test result
The composite analysis of results table of the toxicity test to downy mildew of garpe of table 13 fluorine azoles bacterium acid amides and dithianon
As shown in Table 13, the composite proportioning of downy mildew of garpe of preventing and treating of fluorine azoles bacterium acid amides and dithianon is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, the proportioning of fluorine azoles bacterium acid amides and dithianon is at 1 ︰ 45～5: 1, and synergistic effect is more outstanding; Synergy ratio maximum when fluorine azoles bacterium acid amides and dithianon weight ratio are 1:9, synergistic effect is the most obvious.Testing through the applicant proportioning of finding fluorine azoles bacterium acid amides and dithianon is 1 ︰ 45, 1 ︰ 40, 1 ︰ 35, 1 ︰ 30, 1 ︰ 25, 1 ︰ 20, 1 ︰ 15, 1 ︰ 14, 1 ︰ 13, 1 ︰ 12, 1 ︰ 11, 1 ︰ 10, 1 ︰ 9, 1 ︰ 8, 1 ︰ 7, 1 ︰ 6, 1 ︰ 5, 1 ︰ 4, 1 ︰ 3, 1 ︰ 2, 1 ︰ 1, 2 ︰ 1, 3 ︰ 1, 4 ︰ 1, during 5 ︰ 1 to downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, the control of resin disease has obvious synergistic effect, synergy ratio is all more than 2.00.
Application Example four:
For trying disease: cucumber downy mildew
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of phosethyl-Al and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to cucumber downy mildew of table 14 fluorine azoles bacterium acid amides and phosethyl-Al
As shown in Table 14, the proportioning of fluorine azoles bacterium acid amides and the composite control cucumber downy mildew of phosethyl-Al is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, the proportioning of fluorine azoles bacterium acid amides and phosethyl-Al was at 1: 40～5: 1, and synergistic effect is more outstanding; Synergy ratio maximum when fluorine azoles bacterium acid amides and phosethyl-Al weight ratio are 1:10, synergistic effect is the most obvious.Testing through the applicant proportioning of finding fluorine azoles bacterium acid amides and phosethyl-Al is 1 ︰ 40, 1 ︰ 35, 1 ︰ 30, 1 ︰ 25, 1 ︰ 20, 1 ︰ 15, 1 ︰ 14, 1 ︰ 13, 1 ︰ 12, 1 ︰ 11, 1 ︰ 10, 1 ︰ 9, 1 ︰ 8, 1 ︰ 7, 1 ︰ 6, 1 ︰ 5, 1 ︰ 4, 1 ︰ 3, 1 ︰ 2, 1 ︰ 1, 2 ︰ 1, 3 ︰ 1, 4 ︰ 1, during 5 ︰ 1 to downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, the control of resin disease has obvious synergistic effect, synergy ratio is all more than 2.00.
Application Example five:
For trying disease: early blight of tomato
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of tpn and the two different proportioning mixture through preliminary experiment.
The toxicity test result
Table 15 fluorine azoles bacterium acid amides and the chlorothalonil compound toxicity test analysis of results table to early blight of tomato
As shown in Table 15, fluorine azoles bacterium acid amides and chlorothalonil compound are prevented and treated the proportioning of early blight of tomato when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, the proportioning of fluorine azoles bacterium acid amides and tpn was at 1: 35～5: 1, and synergistic effect is more outstanding; Synergy ratio maximum when fluorine azoles bacterium acid amides and tpn weight ratio are 1:7, synergistic effect is the most obvious.Testing through the applicant proportioning of finding fluorine azoles bacterium acid amides and tpn is 1 ︰ 35, 1 ︰ 30, 1 ︰ 25, 1 ︰ 20, 1 ︰ 15, 1 ︰ 14, 1 ︰ 13, 1 ︰ 12, 1 ︰ 11, 1 ︰ 10, 1 ︰ 9, 1 ︰ 8, 1 ︰ 7, 1 ︰ 6, 1 ︰ 5, 1 ︰ 4, 1 ︰ 3, 1 ︰ 2, 1 ︰ 1, 2 ︰ 1, 3 ︰ 1, 4 ︰ 1, during 5 ︰ 1 to downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, the control of resin disease has obvious synergistic effect, synergy ratio is all more than 2.05.
Application Example six:
For trying disease: grey mould fruit rot of strawberry
Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining fluorine azoles bacterium acid amides and the former medicine of captan and the two different proportioning mixture through preliminary experiment.
The composite analysis of results table of the toxicity test to grey mould fruit rot of strawberry of table 16 fluorine azoles bacterium acid amides and captan
As shown in Table 16, the proportioning of fluorine azoles bacterium acid amides and the composite control grey mould fruit rot of strawberry of captan is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, the proportioning of fluorine azoles bacterium acid amides and captan was at 1: 40～8: 1, and synergistic effect is more outstanding; Synergy ratio maximum when fluorine azoles bacterium acid amides and captan weight ratio are 1:5, synergistic effect is the most obvious.Testing through the applicant proportioning of finding fluorine azoles bacterium acid amides and captan is 1 ︰ 40, 1 ︰ 35, 1 ︰ 30, 1 ︰ 25, 1 ︰ 20, 1 ︰ 15, 1 ︰ 14, 1 ︰ 13, 1 ︰ 12, 1 ︰ 11, 1 ︰ 10, 1 ︰ 9, 1 ︰ 8, 1 ︰ 7, 1 ︰ 6, 1 ︰ 5, 1 ︰ 4, 1 ︰ 3, 1 ︰ 2, 1 ︰ 1, 2 ︰ 1, 3 ︰ 1, 4 ︰ 1, 5 ︰ 1, 6 ︰ 1, 7 ︰ 1, during 8 ︰ 1 to downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, the control of resin disease has obvious synergistic effect, synergy ratio is all more than 2.05.
Application Example seven fluorine azoles bacterium acid amides and active component B and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at Shaanxi Province's Hanzhong City; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrasts 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial).
The investigation rice sheath blight disease state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 17 fluorine azoles bacterium acid amides and active component B and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 17, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat rice sheath blight disease, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example octafluoro azoles bacterium acid amides and active component B and the composite downy mildew of crucifers test of pesticide effectiveness of preventing and treating thereof
This test arrangement is in Weinan City suburb, Shaanxi Province, and contrast 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial) are researched and developed, provided to test medicine by Shaanxi Welch Crop Protection Co., Ltd..
The investigation downy mildew of crucifers state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 3 days, 10 days, 20 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 18 fluorine azoles bacterium acid amides and active component B and the composite downy mildew of crucifers test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 18, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat downy mildew of crucifers, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
The sick test of pesticide effectiveness of Application Example nine fluorine azoles bacterium acid amides and active component B and composite control pear scab thereof
This test arrangement is in the Xianyang, Shanxi province city; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrasts 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial).
The investigation pear scab state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 19 fluorine azoles bacterium acid amides and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 19, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat pear scab, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten fluorine azoles bacterium acid amides and active component B and the test of composite control watermelon powdery mildew effect thereof
This test arrangement is at Shaanxi Province's Weinan City; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrasts 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial).
The investigation watermelon powdery mildew state of an illness, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 20 fluorine azoles bacterium acid amides and active component B and the composite control watermelon powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 20, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat the watermelon powdery mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 11 fluorine azoles bacterium acid amides and active component B and the composite control tea tree anthracnose test of pesticide effectiveness thereof
This experimental establishment is in the Ya'an, Sichuan Province; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrasts 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial).
The investigation tea tree anthracnose state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
The sick test of pesticide effectiveness of table 21 fluorine azoles bacterium acid amides and active component B and composite control tea tree anthracnose thereof
As can be seen from Table 21, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat tea tree anthracnose, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten difluoro azoles bacterium acid amides and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
This test arrangement is at Shaanxi Province's Weinan City; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrasts 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial).
The investigation wheat rust state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 22 fluorine azoles bacterium acid amides and active component B and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 22, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat wheat rust, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten trifluoro azoles bacterium acid amides and active component B and the composite control wild cabbage downy mildew test of pesticide effectiveness thereof
This test arrangement is at the Xi'an City, Shanxi Province Changan District; test medicine is researched and developed, is provided by Shaanxi Welch Crop Protection Co., Ltd., contrasts 24% fluorine azoles bacterium acid amides suspending agent (commercial), 50% Acibenzolar wetting powder (commercial), 80% dithianon water-dispersion granule (commercial), 40% phosethyl-Al wetting powder (commercial), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial).
The investigation wild cabbage downy mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 3 days, 10 days, 20 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 23 fluorine azoles bacterium acid amides and active component B and the composite control wild cabbage downy mildew test of pesticide effectiveness thereof
As can be seen from Table 23, fluorine azoles bacterium acid amides and active component B and composite after can effectively prevent and treat wild cabbage downy mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
After through different local throughout the country tests, draw, fluorine azoles bacterium acid amides and Acibenzolar, dithianon, phosethyl-Al, tpn, captan is composite rear to the downy mildew on various crop, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, the preventive effect that resin is sick waits Common Diseases all 95% with on excellent, in the single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition of a fluorine-containing azoles bacterium acid amides, it is characterized in that: contain active components A and active component B, active components A and active component B weight ratio are 1: 80～60: 1, described active components A is selected from fluorine azoles bacterium acid amides, and active component B is selected from a kind of in Acibenzolar, dithianon, phosethyl-Al, tpn, captan.
2. the bactericidal composition of fluorine-containing azoles bacterium acid amides according to claim 1, it is characterized in that: the weight ratio of active components A and active component B is 1: 60～50: 1.
3. the bactericidal composition of fluorine-containing azoles bacterium acid amides according to claim 2 is characterized in that:
The weight ratio of fluorine azoles bacterium acid amides and Acibenzolar is 1: 5～30: 1;
The weight ratio of fluorine azoles bacterium acid amides and dithianon is 1: 45～5: 1;
The weight ratio of fluorine azoles bacterium acid amides and phosethyl-Al is 1: 40～5: 1;
The weight ratio of fluorine azoles bacterium acid amides and tpn is 1: 35～5: 1;
The weight ratio of fluorine azoles bacterium acid amides and captan is 1 ︰ 40～8 ︰ 1.
4. according to the bactericidal composition of the described fluorine-containing azoles bacterium acid amides of any one in claim 1～3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
5. the bactericidal composition of fluorine-containing azoles bacterium acid amides according to claim 4 is for preventing and treating the purposes of crop pest.
6. purposes according to claim 5, it is characterized in that: described disease comprises downy mildew, gray mold, leaf mold, anthracnose, rust, leaf spot, moire disease, net blotch, banded sclerotial blight, epidemic disease, balck shank, powdery mildew, canker, scab, ring spot, black spot, shot hole, spot defoliation, anthrachose of grape, rice blast, climing rot, rust, resin disease.
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| CN109566637A (en) * | 2017-09-29 | 2019-04-05 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN114304166A (en) * | 2022-02-27 | 2022-04-12 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition for preventing and controlling gummy stem blight |
| CN114304166B (en) * | 2022-02-27 | 2024-04-09 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Sterilization composition for preventing and controlling gummy stem blight of melons |
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