CN102639536B - 吡啶衍生物的无水晶型 - Google Patents
吡啶衍生物的无水晶型 Download PDFInfo
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- CN102639536B CN102639536B CN201080037918.3A CN201080037918A CN102639536B CN 102639536 B CN102639536 B CN 102639536B CN 201080037918 A CN201080037918 A CN 201080037918A CN 102639536 B CN102639536 B CN 102639536B
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
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- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23743509P | 2009-08-27 | 2009-08-27 | |
| US61/237,435 | 2009-08-27 | ||
| PCT/EP2010/062420 WO2011023733A1 (en) | 2009-08-27 | 2010-08-25 | Anhydrate forms of a pyridine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102639536A CN102639536A (zh) | 2012-08-15 |
| CN102639536B true CN102639536B (zh) | 2015-03-18 |
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|---|---|---|---|
| CN201080037918.3A Active CN102639536B (zh) | 2009-08-27 | 2010-08-25 | 吡啶衍生物的无水晶型 |
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Cited By (1)
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| CN112292132A (zh) * | 2018-03-14 | 2021-01-29 | KaNDy治疗有限公司 | 含有双重nk-1/nk-3受体拮抗剂的新颖的药物制剂 |
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| MX2012002369A (es) * | 2009-08-27 | 2012-03-29 | Glaxosmithkline Llc | Formas de anhidrato de un derivado de piridina. |
| ES2879375T3 (es) | 2014-06-25 | 2021-11-22 | Univ Emory | Procedimientos de manejo del miedo condicionado con antagonistas del receptor de neuroquinina |
| MX377052B (es) * | 2015-05-18 | 2025-03-07 | Kandy Therapeutics Ltd | Antagonistas duales de receptores de neurocinina-1 (nk-1) / neurocinina-3 (nk-3) para el tratamiento de enfermedades dependientes de hormonas sexuales. |
| WO2018109646A1 (en) * | 2016-12-15 | 2018-06-21 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 compounds |
| WO2021030335A1 (en) * | 2019-08-12 | 2021-02-18 | Millendo Therapeutics, Inc. | A stereoisomerically pure nk-3 receptor antagonist and crystalline forms thereof |
| AU2020381762A1 (en) * | 2019-11-15 | 2022-06-02 | KaNDy Therapeutics Limited | New chemical process for making 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine a key intermediate of NT-814 |
| EP4431512A1 (en) | 2023-03-16 | 2024-09-18 | Bayer Consumer Care AG | Novel dual nk-1/nk-3 receptor antagonists |
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| ES2359235T3 (es) * | 1999-02-24 | 2011-05-19 | F. Hoffmann-La Roche Ag | Derivados de 4-fenilpiridina y su empleo como antagonistas del receptor nk-1. |
| GB0203022D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| ATE366576T1 (de) * | 2003-01-31 | 2007-08-15 | Hoffmann La Roche | Neue kristallmodifikation von 2-(3,5-bis- trifluormethyl-phenyl)-n-6-(1,1-dioxo-1lamda-6- |
| WO2005002577A1 (en) * | 2003-07-03 | 2005-01-13 | F. Hoffmann-La Roche Ag | Dual nk1/nk3 antagonists for treating schizophrenia |
| MY145713A (en) * | 2005-09-09 | 2012-03-30 | Smithkline Beecham Corp | Hexahydropyrazino [2,1-c][1,4]oxazin-8(1h)-yl pyridine derivatives and their use in the treatment of psychotic disorders |
| AU2008346110A1 (en) * | 2007-12-11 | 2009-07-16 | Cipla Ltd. | Crystalline polymorphic forms of zopiclone, processes for their preparation and their pharmaceutical compositions |
| GB0814340D0 (en) * | 2008-08-05 | 2008-09-10 | Smithkline Beecham Corp | Anhydrous crystol form fo a pyridine derivative |
| MX2012002369A (es) * | 2009-08-27 | 2012-03-29 | Glaxosmithkline Llc | Formas de anhidrato de un derivado de piridina. |
| JP6342662B2 (ja) * | 2014-01-29 | 2018-06-13 | 京セラ株式会社 | ドリルおよびそれを用いた切削加工物の製造方法 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112292132A (zh) * | 2018-03-14 | 2021-01-29 | KaNDy治疗有限公司 | 含有双重nk-1/nk-3受体拮抗剂的新颖的药物制剂 |
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| AU2010288502B2 (en) | 2013-12-12 |
| BR112012003435A2 (pt) | 2016-02-23 |
| JP2017193564A (ja) | 2017-10-26 |
| MX2012002369A (es) | 2012-03-29 |
| JP2013503134A (ja) | 2013-01-31 |
| JP6404186B2 (ja) | 2018-10-10 |
| EA201270302A1 (ru) | 2012-07-30 |
| ES2440938T3 (es) | 2014-01-31 |
| JP2016000739A (ja) | 2016-01-07 |
| CA2772168A1 (en) | 2011-03-03 |
| US8796269B2 (en) | 2014-08-05 |
| IL217922A0 (en) | 2012-03-29 |
| WO2011023733A1 (en) | 2011-03-03 |
| CA2772168C (en) | 2019-01-08 |
| EP2470545B1 (en) | 2013-10-09 |
| PL2470545T3 (pl) | 2014-03-31 |
| IL217922A (en) | 2016-06-30 |
| EA021411B1 (ru) | 2015-06-30 |
| AU2010288502A1 (en) | 2012-02-23 |
| ZA201200812B (en) | 2013-03-27 |
| IN2012DN01292A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-06-05 |
| CN102639536A (zh) | 2012-08-15 |
| DK2470545T3 (da) | 2014-01-13 |
| EP2470545A1 (en) | 2012-07-04 |
| KR20120056258A (ko) | 2012-06-01 |
| SG178231A1 (en) | 2012-03-29 |
| US20120157450A1 (en) | 2012-06-21 |
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