CN102626471A - Traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration - Google Patents
Traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration Download PDFInfo
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- CN102626471A CN102626471A CN2012100807257A CN201210080725A CN102626471A CN 102626471 A CN102626471 A CN 102626471A CN 2012100807257 A CN2012100807257 A CN 2012100807257A CN 201210080725 A CN201210080725 A CN 201210080725A CN 102626471 A CN102626471 A CN 102626471A
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Abstract
The invention belongs to the field of medicine technology, and in particular relates to a traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration. The traditional Chinese medicine composition of the invention selects four medicinal materials of wild grapevine, Chinese actinidia root, almond and Ganoderma lucidum. Modern pharmacology research and clinical trials have shown that the traditional Chinese medicine composition of the invention has functions of antibiosis, reducing inflammation, relieving, promoting epidermal regeneration and enhancing the vitality thereof, can be effectively resist anaphylaxis and help the skin repair and reconstruction, so as to achieve effects of anti-anaphylaxis, desensitization, repair, regeneration, whitening wrinkle proof, beautifying. Meanwhile, the medicinal materials have no toxicity and little drug dependence for long-term use, and are at low prices; therefore, the traditional Chinese medicine composition is suitable for ordinary consumers to use, and has wide market prospect.
Description
Technical field
The invention belongs to medical technical field, relate in particular to a kind of Chinese medicine composition with anti-anaphylaxis desensitization, reparative regeneration effect.
Background technology
The quickening work of Along with people's rhythm of life; Work and life stress increase day by day; Add environmental pollution and diet problem, people's skin problem is highlighted gradually, dim complexion, pachylosis sensitivity, pore expansion, brown patch, acne, tiny wrinkle etc. are perplexing the vast women who likes to be beautiful.How Along with people's growth in the living standard and to the attention of health keeps the pale delicacy of skin, soft smooth high resilience, improves skin sensitivity, avoids generation hypersensitive, and the state of maintaining the beautiful youth is the problem that people extremely are concerned about.
Summary of the invention
In view of this; The object of the present invention is to provide a kind of Chinese medicine composition with anti-anaphylaxis desensitization, reparative regeneration effect; The damaged skin that said Chinese medicine composition can be repaired a variety of causes makes skin regeneration; Improve the skin allergic symptom, improve the toleration of skin, have the effect wrinkle resistant, cleaning and nourishing of whitening simultaneously concurrently anaphylactogen.
For realizing the object of the invention, the present invention adopts following technical scheme:
A kind of Chinese medicine composition with anti-anaphylaxis desensitization, reparative regeneration effect is by waiting following raw material of weight portion to process: Herba Anemones vitifoliae extract, Radix Actinidiae Chinensis Chinensis extrat, Semen Armeniacae Amarum extract, Ganoderma extract.
Chinese medicine composition according to the invention is selected for use the extract of four flavors such as Herba Anemones vitifoliae, Radix Actinidiae Chinensis, Semen Armeniacae Amarum and Ganoderma Chinese crude drug to mix and is processed.
Wherein, Herba Anemones vitifoliae, the another name Herba Anemones vitifoliae is the Herb and the leaf of vitaceae downy grape, sweet in the mouth, property are flat, have the effect of hemostasis, clearing away heat-damp and promoting diuresis, antiabortive, analgesic, subduing swelling and detoxicating, cure mainly diseases such as measles, dysentery, sore swollen toxin.
Radix Actinidiae Chinensis is the root of Actinidiaceae plant Actinidia arguta Sieb.et Zucc; Sour in the mouth, puckery, cool in nature; Effect with heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, expelling wind and removing dampness, diuresis hemostasis, removing toxic substances and promoting subsidence of swelling, hemostasis cures mainly diseases such as jaundice, dyspepsia, vomiting, rheumatic arthralgia, digestive tract cancerous protuberance, carbuncle and ulcer furuncle, traumatic injury, traumatic hemorrhage, agalactia, rheumatic ostalgia and jaundice.
Semen Armeniacae Amarum is the seed of rosaceous plant peach, Amygdaluscommunis L., Fructus Pruni, Lee, prunus mume (sieb.) sieb.et zucc., whitethorn, Folium Eriobotryae etc.; Warm in nature, bitter in the mouth; Slightly poisonous, have the effect of sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation, be used for the treatment of diseases such as cough and asthma, fullness in the chest abundant expectoration, blood deficiency Tianjin are withered, hot dry constipation.
Ganoderma is claimed Ganoderma lucidum seu Japonicum, Ganoderma, ZHICAO, Herba mesonae chinensis, Ganoderma again, is the Herb of Polyporaceae plant Ganoderma lucidum (Leyss. Ex Fr.) Karst. or Ganoderma, and sweet in the mouth, property are put down, and cure mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.
The said Herba Anemones vitifoliae extract of Chinese medicine composition according to the invention, Radix Actinidiae Chinensis Chinensis extrat, Semen Armeniacae Amarum extract and Ganoderma extract are commercial product, can buy through the commercial channel to obtain, and also can prepare.
Preferably, said Herba Anemones vitifoliae preparation method of extract is: get the decocting that Herba Anemones vitifoliae adds 6-8 times of weight and boil 2-4 time, and each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
Preferably, the method for preparing of said Radix Actinidiae Chinensis Chinensis extrat is: get the decocting that Radix Actinidiae Chinensis adds 6-8 times of weight and boil 2-4 time, and each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
Preferably, said Semen Armeniacae Amarum preparation method of extract is: get the decocting that Semen Armeniacae Amarum adds 6-8 times of weight and boil 2-4 time, and each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
Preferably, the method for preparing of said Ganoderma extract is: get the decocting that Ganoderma adds 6-8 times of weight and boil 2-4 time, and each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
The present invention also provides the clinical preparation of said Chinese medicine composition.It is required various pharmaceutically conventional adjuvants that those skilled in the art can add the preparation different dosage form with Chinese medicine composition according to the invention according to requirement of different patients; Like disintegrating agent, lubricant, emulsifying agent, binding agent etc.; With conventional method of Chinese medicinal, process common dosage forms such as tablet, capsule, oral liquid, pill, granule, powder, drop pill, spray, emulsifiable paste etc. through the direct or indirect adding acceptable auxiliary pharmaceutically of conventional processing.
Preferably, the clinical preparation of Chinese medicine composition according to the invention is an emulsifiable paste, can directly act on the affected part, and with strong points, curative effect is obvious.
The invention provides a kind of emulsifiable paste, process by following weight portion raw material with anti-anaphylaxis desensitization, reparative regeneration effect:
Said Chinese medicine composition 20g, glyceryl monostearate 35g, stearic acid 130g, liquid Paraffin 50mL, azone 20mL, simethicone 20g, Borax 4g, allantoin 3g, glycerol 50mL, propylene glycol 50mL, ethyl hydroxybenzoate 1.5g, dodecylphosphoric acid sodium 4g, triethanolamine 10mL and purified water 653mL with anti-anaphylaxis desensitization, reparative regeneration effect.
The invention provides said method for preparing, may further comprise the steps with emulsifiable paste of anti-anaphylaxis desensitization, reparative regeneration effect
Step 1: get glyceryl monostearate, stearic acid, liquid Paraffin, azone and simethicone be mixed and heated to 85 ℃ subsequent use;
Step 2: get have anti-anaphylaxis desensitization, the Chinese medicine composition of reparative regeneration effect, glycerol, Borax, sodium lauryl sulphate, allantoin, purified water, ethyl hydroxybenzoate, mixed with propylene glycol according to the invention; Be heated to 85 ℃; Add triethanolamine then and continue to be heated to 85 ℃; Mix to emulsifying with step 1 mixture, cooling promptly gets.
The using dosage of pharmaceutical composition of the present invention and method for using depend on many factors, comprise activity intensity, Time of Administration, metabolic rate, the degree that is in a bad way and the diagnosis and treatment doctor's of patient's age, body weight, sex, natural health situation, nutriture, chemical compound subjective judgment.Those skilled in the art can easily determine the using dosage and the method for using of pharmaceutical composition according to above-mentioned factor.
Preferably, its effective dose of pharmaceutical composition of the present invention is calculated with contained crude drug amount in the Chinese medicine composition of the present invention, is each 2g, 2 times on the one.
The present invention in 60 routine patients with allergic dermatosis, uses traditional Chinese medicine composition for treating according to the invention through clinical observation on the therapeutic effect, cures 54 examples, and cure rate accounts for 90%, produce effects 5 examples, and total effective rate is 98.3%, invalid 1 example, inefficiency accounts for 1.7%.In 60 routine acne scars patients, use traditional Chinese medicine composition for treating according to the invention, cure 12 examples, cure rate accounts for 20%, produce effects 43 examples, total effective rate is 91.7%, invalid 5 examples, inefficiency accounts for 8.3%.Continue to use emulsifiable paste according to the invention more than half a year, cure rate obviously increases.60 routine patients with allergic dermatosis of being treated and 60 routine acne scars patients do not have an example untoward reaction to occur, show that Chinese medicine composition according to the invention is to the human body safety non-toxic.
The invention provides a kind of Chinese medicine composition of determined curative effect with anti-anaphylaxis desensitization, reparative regeneration effect; Modern pharmacology research and clinical trial show, that Chinese medicine composition according to the invention has is antibiotic, antiinflammatory, the effect of releiving and promoting promoting epidermization and improving its vitality, effectively antiallergic, help skin repair to rebuild; Reach anti-anaphylaxis desensitization, reparative regeneration, the effect of wrinkle resistant, the cleaning and nourishing of whitening, looks improving and the skin nourishing; Used medical material is all nontoxic simultaneously, and the life-time service drug dependence is little, and cheap; Be fit to ordinary consumer and use, have vast market prospect.
The specific embodiment
The embodiment of the invention discloses a kind of anti-anaphylaxis desensitization, reparative regeneration drug composition on that has.Those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are regarded as and are included in the present invention.Chinese medicine composition of the present invention is described through preferred embodiment; The related personnel obviously can change or suitably change and combination Chinese medicine composition as herein described in not breaking away from content of the present invention, spirit and scope, realizes and use technology of the present invention.
In order further to understand the present invention, below in conjunction with embodiment the present invention is provided to be elaborated.
Embodiment 1: the Chinese medicine composition of anti-anaphylaxis desensitization according to the invention, reparative regeneration effect
Said Chinese medicine composition is to be processed by following bulk drugs:
Herba Anemones vitifoliae extract 5g, Radix Actinidiae Chinensis Chinensis extrat 5g, Semen Armeniacae Amarum extract 5g, Ganoderma extract 5g.
The Herba Anemones vitifoliae preparation method of extract is: gets the decocting that Herba Anemones vitifoliae adds 6 times of weight and boils 3 times, and each 2 hours, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get; The method for preparing of Radix Actinidiae Chinensis Chinensis extrat is: gets the decocting that Radix Actinidiae Chinensis adds 8 times of weight and boils 3 times, and each 2 hours, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get; The Semen Armeniacae Amarum preparation method of extract is: gets the decocting that Semen Armeniacae Amarum adds 6 times of weight and boils 4 times, and each 2 hours, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get; Ganoderma extract: get the decocting that Ganoderma adds 6 times of weight and boil 3 times, each 2 hours, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
Embodiment 2: the emulsifiable paste of anti-anaphylaxis desensitization according to the invention, reparative regeneration effect
Get 20g Chinese medicine composition according to the invention, 35g glyceryl monostearate, 130g stearic acid, 50mL liquid Paraffin, 20mL azone and 20g simethicone be mixed and heated to 85 ℃ subsequent use;
Getting 50mL glycerol, 4g Borax, 4g sodium lauryl sulphate, 3g allantoin, 1.5g ethyl hydroxybenzoate, 50mL propylene glycol and 653mL purified water mixes; Be heated to 85 ℃, add the 10mL triethanolamine then and continue to be heated to 85 ℃, mix to emulsifying with the mixture of gained; Cooling promptly gets.
Embodiment 3: anti-anaphylaxis desensitization clinical observation on the therapeutic effect:
Select skin of face that 110 of the women of 20～50 rubescent, as allergic symptom such as to itch one full year of life are arranged, carry out routine examination before on probation: electrocardiogram, hematuria are just conventional, the equal no abnormality seen of hepatic and renal function.110 people are divided into two groups at random.Receive examination to organize 60 examples; Matched group 50 examples.Organized by examination: the emulsifiable paste according to the invention that behind the clean skin embodiment 2 is prepared sooner or later evenly is applied in the rubescent place of itching, and massages gently 1～3 minute, uses continuously 7 days, and the trial employment period is avoided irritable food on probation, the careful zest cosmetics of using.Matched group: smear a little PIYANPING in the rubescent place of itching behind the clean skin sooner or later, and massaged gently 1～3 minute, used continuously 7 days, the trial employment period is avoided irritable food on probation, the careful zest cosmetics of using.Table 1 is seen in statistical result
Curative effect determinate standard:
Cure: the inspection skin rubefaction symptom complete obiteration of itching after the medication, observe not recurrence in 7 days continuously.
Produce effects: symptom obviously alleviates after the medication.
Invalid: symptom does not have and alleviates after the medication, or has and increase the weight of.
Table 1 clinical observation on the therapeutic effect
According to the inventionly receive examination to organize 60 philtrums 54 people's allergic symptom complete obiterations are arranged by table 1 observed result is visible; 5 people's allergic symptoms are clearly better, and it is little that it remains the variation of 1 people's allergic symptom, and total effective rate reaches 98.3%; Do not have an example untoward reaction to occur, the matched group total effective rate is merely 12%.The result shows, Chinese medicine composition according to the invention has the effect of anti-anaphylaxis desensitization, and is to the human body safety non-toxic, remarkable for skin rubefaction, the irritated therapeutic effect of itching.
Embodiment 4: reparative regeneration effect clinical observation on the therapeutic effect:
Select the skin of face acne scars obviously, 110 of 15～35 patients of unsystematic disease, carry out routine examination before on probation: electrocardiogram, hematuria are just conventional, the equal no abnormality seen of hepatic and renal function.110 people are divided into two groups at random.Receive examination to organize 60 examples; Matched group 50 examples, every group of M-F is similar.Organized by examination: the emulsifiable paste according to the invention that behind the clean skin embodiment 2 is prepared sooner or later evenly is applied in face, and massages gently 1～3 minute, uses continuously 30 days.Matched group: smear a little dimension E WEIFU GAO sooner or later behind the clean skin in face, and massaged gently 1～3 minute, used continuously 30 days.Table 1 is seen in statistical result
Curative effect determinate standard:
Cure: the skin acne scars is obviously desalinated after the medication, and shrink in acne depression hole.
Produce effects: skin acne scars desalination after the medication.
Invalid: the skin acne scars does not have and alleviates after the medication.
Table 1 clinical observation on the therapeutic effect
According to the inventionly receive examination to organize 60 philtrums to have 12 people's acne scars obviously to desalinate by table 1 observed result is visible, shrink in acne depression hole, the desalination of 43 people's acne scars; It is little that it remains 5 people's symptom variation; Total effective rate reaches 91.7%, does not have an example untoward reaction to occur, and the matched group total effective rate is merely 16%.And continuing to use emulsifiable paste according to the invention more than half a year, cure rate obviously increases.The result shows that Chinese medicine composition according to the invention has the effect of reparative regeneration, and is to the human body safety non-toxic, remarkable for skin acne scars therapeutic effect.
The explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof.Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of claim of the present invention.
Claims (9)
1. the Chinese medicine composition with anti-anaphylaxis desensitization, reparative regeneration effect is characterized in that, by waiting following raw material of weight portion to process: Herba Anemones vitifoliae extract, Radix Actinidiae Chinensis Chinensis extrat, Semen Armeniacae Amarum extract, Ganoderma extract.
2. according to the said cosmetic cream of claim 1, it is characterized in that said Herba Anemones vitifoliae preparation method of extract is: get the decocting that Herba Anemones vitifoliae adds 6-8 times of weight and boil 2-4 time, each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
3. according to the said cosmetic cream of claim 1, it is characterized in that the method for preparing of said Radix Actinidiae Chinensis Chinensis extrat is: get the decocting that Radix Actinidiae Chinensis adds 6-8 times of weight and boil 2-4 time, each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
4. according to the said cosmetic cream of claim 1, it is characterized in that said Semen Armeniacae Amarum preparation method of extract is: get the decocting that Semen Armeniacae Amarum adds 6-8 times of weight and boil 2-4 time, each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
5. according to the said cosmetic cream of claim 1, it is characterized in that the method for preparing of said Ganoderma extract is: get the decocting that Ganoderma adds 6-8 times of weight and boil 2-4 time, each 1-3 hour, merge extractive liquid,, the dry powder of beating, mistake 100 mesh sieves promptly get.
6. the clinical preparation that comprises any said Chinese medicine composition of claim 1～5.
7. according to the said clinical preparation of claim 6, it is characterized in that it is an emulsifiable paste.
8. the emulsifiable paste with anti-anaphylaxis desensitization, reparative regeneration effect is characterized in that, is processed by following weight portion raw material:
Said Chinese medicine composition 20g, glyceryl monostearate 35g, stearic acid 130g, liquid Paraffin 50mL, azone 20mL, simethicone 20g, Borax 4g, allantoin 3g, glycerol 50mL, propylene glycol 50mL, ethyl hydroxybenzoate 1.5g, dodecylphosphoric acid sodium 4g, triethanolamine 10mL and the purified water 653mL of claim 1 with anti-anaphylaxis desensitization, reparative regeneration effect.
9. the said method for preparing with emulsifiable paste of anti-anaphylaxis desensitization, reparative regeneration effect of claim 8 is characterized in that, may further comprise the steps
Step 1: get glyceryl monostearate, stearic acid, liquid Paraffin, azone and simethicone be mixed and heated to 85 ℃ subsequent use;
Step 2: the weighting profit requires 1 saidly to have anti-anaphylaxis desensitization, the Chinese medicine composition of reparative regeneration effect, glycerol, Borax, sodium lauryl sulphate, allantoin, purified water, ethyl hydroxybenzoate, a mixed with propylene glycol; Be heated to 85 ℃; Add triethanolamine then and continue to be heated to 85 ℃; Mix to emulsifying with step 1 mixture, cooling promptly gets.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210080725 CN102626471B (en) | 2012-03-23 | 2012-03-23 | Traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201210080725 CN102626471B (en) | 2012-03-23 | 2012-03-23 | Traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration |
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| CN102626471A true CN102626471A (en) | 2012-08-08 |
| CN102626471B CN102626471B (en) | 2013-12-25 |
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| CN 201210080725 Expired - Fee Related CN102626471B (en) | 2012-03-23 | 2012-03-23 | Traditional Chinese medicine composition with effects of anti-anaphylaxis, desensitization, repair and regeneration |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190041691A (en) * | 2017-10-13 | 2019-04-23 | 주식회사 코리아나화장품 | Cosmetic composition for anti-allergy and for improving atopic dermatitis comprising extract of anemone reflexa stephan as active ingredient |
| CN113940914A (en) * | 2021-10-15 | 2022-01-18 | 江苏集萃新型药物制剂技术研究所有限公司 | Transdermal ointment, drug-loaded composition and drug-loaded preparation thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1139566A (en) * | 1995-06-30 | 1997-01-08 | 刘会霖 | Medicine for acne and production technology |
| CN1307898A (en) * | 2000-12-13 | 2001-08-15 | 王清纯 | Chinese medicine liniment for treating acne fast |
| CN101757056A (en) * | 2008-12-23 | 2010-06-30 | 首都医科大学 | Extract of yangtao actinidia root and preparation method and applications thereof |
-
2012
- 2012-03-23 CN CN 201210080725 patent/CN102626471B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1139566A (en) * | 1995-06-30 | 1997-01-08 | 刘会霖 | Medicine for acne and production technology |
| CN1307898A (en) * | 2000-12-13 | 2001-08-15 | 王清纯 | Chinese medicine liniment for treating acne fast |
| CN101757056A (en) * | 2008-12-23 | 2010-06-30 | 首都医科大学 | Extract of yangtao actinidia root and preparation method and applications thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190041691A (en) * | 2017-10-13 | 2019-04-23 | 주식회사 코리아나화장품 | Cosmetic composition for anti-allergy and for improving atopic dermatitis comprising extract of anemone reflexa stephan as active ingredient |
| KR101974502B1 (en) | 2017-10-13 | 2019-05-03 | 주식회사 코리아나화장품 | Cosmetic composition for anti-allergy and for improving atopic dermatitis comprising extract of anemone reflexa stephan as active ingredient |
| CN113940914A (en) * | 2021-10-15 | 2022-01-18 | 江苏集萃新型药物制剂技术研究所有限公司 | Transdermal ointment, drug-loaded composition and drug-loaded preparation thereof |
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