CN102614232A - Acer truncatum health-care lozenge and preparation method thereof - Google Patents
Acer truncatum health-care lozenge and preparation method thereof Download PDFInfo
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- CN102614232A CN102614232A CN201210121141XA CN201210121141A CN102614232A CN 102614232 A CN102614232 A CN 102614232A CN 201210121141X A CN201210121141X A CN 201210121141XA CN 201210121141 A CN201210121141 A CN 201210121141A CN 102614232 A CN102614232 A CN 102614232A
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- acer truncatum
- truncatum buge
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Abstract
The invention discloses a health-care lozenge prepared by taking an acer truncatum extract as a major raw material and a preparation method thereof. The health-care lozenge is prepared from the following raw materials in percentage by weight: 20-40 percent of an acer truncatum extract, 15-25 percent of an acer truncatum seed extract, 30-64 percent of a seasoning agent and 1-5 percent of a nutrition fortifier. A tablet is prepared by performing deep processing on terrestrial plant acer truncatum seeds which are rich in nervonic acid and terrestrial plant acer truncatum leaves which are rich in flavone, and has the effects of preventing nerve fiber atrophy, promoting brain development, delaying ageing and enhancing the immunity and digestive function of a human body; and over-high blood fat concentration in blood can be lowered remarkably, and the occurrence probability of diseases such as certain hypertension and cardiovascular and cerebrovascular diseases, blood circulation disorder, and the like is lowered.
Description
Technical field
The present invention relates to field of health care products, be specifically related to a kind of Acer Truncatum Buge extract that utilizes and be health care buccal tablets of primary raw material preparation and preparation method thereof.
Background technology
Acer Truncatum Buge (Acer Truncatum Buge) is Aceraceae Acer (Acer) deciduous tree; Because of exactly liking Ancient Chinese generation " ingot ", the Myriopteron extensum (Wight) K. Schum shape gains the name; Distribute wider in China; After carrying out systematic study through chemical constituent, medical value, find that Acer Truncatum Buge has bigger value of exploiting and utilizing as food, medicine and industrial chemicals to Acer Truncatum Buge.
Be rich in flavone, chlorogenic acid, cardiotonic glycoside, tannin, vitamin, trace element, aminoacid etc. in the leaf of Acer Truncatum Buge; Have prevention and control coronary heart disease; Angina pectoris, disturbance of blood circulation property disease and antiviral; Anti-inflammatory and choleretic is eliminated effects such as human free radical, is a kind of good raw material of preparation health product.
Acer Truncatum Buge seed oil content is higher, can reach 45%-48%, is rich in nervonic acid (Nervonic Acid) in the Acer Truncatum Buge oil, and its chemical name is suitable-15-tetracosenoic acid (cis-15-Tera cosenic Acid), molecular formula C
24H
46O
2, white powdery solid under the room temperature.Because it is mainly derived from deep-sea shark and shark oil; Have another name called shark acid (Selach oleic Acid); Because of being found in mammiferous nervous tissue the earliest, so the called after nervonic acid is biomembranous important composition composition; Usually as the mark of medullary substance in the brain glycoside, participate in the relevant multiple special physiological function of biomembrane.During forming, the Acer Truncatum Buge oil fatty acid contains the nervonic acid of 5%-6%; The plant that contains nervonic acid is less in distributed in nature; International market epineural acid resource is compared with abyssal fishes mainly from abyssal fishes, and Acer Truncatum Buge is the nervonic acid new resources of sustainable use; Nervonic acid has become consistent generally acknowledge unique in the world of various countries scientist can repair brain impaired " neurotransmission passage ", and impels the magical material of economic benefits and social benefits, high energy of " neuranagenesis ".
Nervonic acid is suitability for industrialized production not as yet so far, and chemosynthesis nervonic acid complex process, productive rate are low, can't realize industrialization; From shark oil and shark brain, extract, receive resource restriction, also can't produce in batches.The research institutions that more than ten country arranged at present in the world are in the research of carrying out nervonic acid; Its nervonic acid is mainly derived from marine animal; China starts late to the research of nervonic acid; Listed in the scientific research project by country, Zhejiang University extracts nervonic acid and processes health food from the marine algae plant, the domestic and international at present report that also from terrestrial plant, extracts nervonic acid and process health food.
Summary of the invention
The present invention provides in a kind of terrestrial plant leaf of Acer Truncatum Buge and the seed through the flavone extract of certain conditions and technology extraction and health care buccal tablets that nervonic acid is mixed and made into and preparation method thereof.
Technical scheme of the present invention: a kind of Acer Truncatum Buge health care buccal tablets, process by following materials by weight percentage:
Leaf of Acer Truncatum Buge extract 20-40%
Acer Truncatum Buge seed extract 15-25%
Flavoring agent 30-64%
Nutrition enhancer 1-5%
Said leaf of Acer Truncatum Buge extract is a flavone.
Said Acer Truncatum Buge seed extract is nervonic acid.
Said flavoring agent is a kind of or its any mixing of glucose, xylitol, Mentholum.
Said nutrition enhancer is calcium lactate or Margarita powder.
The method for preparing of Acer Truncatum Buge health care buccal tablets is prepared by following steps:
(1), the Acer Truncatum Buge seed through shelling handle, crude oil is produced, dewatering and filtering, low temperature are analysed layer, separating saturated fatty acid, Acer Truncatum Buge seed extract: nervonic acid;
(2), leaf of Acer Truncatum Buge is through Screening Treatment, leaf pulverizing, lixiviate, filtration, macroporous resin adsorption separation, concentrating under reduced pressure, abstraction impurity removal, vacuum drying, pulverizing, obtains leaf of Acer Truncatum Buge extract: flavone;
(3), allocate step (1), (2) gained raw material into flavoring agent, nutrition enhancer, compounding is even, granulates, tabletting, makes finished product.
Leaf is pulverized and is the big fractionlet of 1cm in the step (2).
Lixiviating solution is that 5～15 times of distilled water or the concentration expressed in percentage by volume content of raw material consumption are 40～70% ethanol in the step (2), extraction temperature 60-80 ℃, and extraction time 2-4 hour.
Technique effect of the present invention: leaf of Acer Truncatum Buge is rich in flavone up to more than 7%; Adopt lixiviate to separate leaf of Acer Truncatum Buge with macroporous resin adsorption; The gained flavones content can reach 35%, and flavone has prevention and treatment coronary heart disease, angina pectoris, disturbance of blood circulation property disease and antiviral; Anti-inflammatory and choleretic is eliminated multiple efficacies such as human free radical; Content of fatty acid is up to 48% in the Acer Truncatum Buge seed, and what the processing Acer Truncatum Buge oil adopted all is physical method, and production cost is low; After adopting vacuum dehydration filtration and low temperature to analyse layer separating saturated fatty acid; Make edible oil unsaturated fatty acid content up to standard higher, product more has no side effect, and contains nervonic acid 5%-7% in the Acer Truncatum Buge oil; Nervonic acid is brain development and the essential nutrient of keeping, and has the brain development of promotion, improves memory, slow down aging, resisting fatigue, blood fat reducing multiple efficacies; Human body self is difficult to generate nervonic acid; Can only lean on external picked-up to replenish; The terrestrial plant Acer Truncatum Buge seed that nervonic acid is rich in utilization of the present invention is processed tablet with the terrestrial plant leaf of Acer Truncatum Buge that is rich in flavone through deep processing, has the atrophy of prevention nerve fiber, promotes brain development, slow down aging, enhancing human immune and digestive function; Can obviously reduce serum lipid concentrations too high in the blood; The incidence probability of the diseases such as some hypertension, cardiovascular and cerebrovascular disease and disturbance of blood circulation property that alleviation causes because of hyperlipidemia; The crowd who is particularly suitable for person in middle and old age and is engaged in mental work for a long time has the good health care therapeutical effect to coronary heart disease, angina pectoris, disturbance of blood circulation property disease etc.
Buccal tablet survey report of the present invention such as following table:
| Inspection item | Measurement unit | Touchstone | Assay |
| AFB1 | μg/kg | ≤5 | ＜5 |
| Acid value | mgKOH/g | ≤3 | 0.45 |
| Peroxide value | g/100g | ≤0.25 | 0.12 |
| Plumbous (in Pb) | mg/kg | ≤1.5 | ＜0.2 |
| Arsenic (in As) | mg/kg | ≤1.0 | ＜0.1 |
| Hydrargyrum (in Hg) | mg/kg | ≤0.3 | ＜0.02 |
| Benzene hexachloride | mg/kg | ≤0.05 | 0.04 |
| DDT | mg/kg | ≤0.05 | ＜0.01 |
| Flavone | g/100g | ≥15 | 35 |
| Chlorogenic acid | g/100g | ≥20 | 25.3 |
| Linoleic acid | g/100g | ≥50 | 55.7 |
| Oleic acid | g/100g | ≥20 | 22.3 |
| Nervonic acid | g/100g | ≥1.0 | 1.31 |
| Total plate count | cfu/g | ≤1000 | ＜10 |
| Coliform | MPN | ≤40 | ＜30 |
| Mycete | cfu/g | ≤25 | ＜10 |
| Yeast | cfu/g | ≤25 | ＜10 |
| Salmonella | / | Must not detect | Do not detect |
| Shigella | / | Must not detect | Do not detect |
| Staphylococcus aureus | / | Must not detect | Do not detect |
| Hemolytic streptococcus | / | Must not detect | Do not detect |
The usefulness of Acer Truncatum Buge health care buccal tablets sees the following form:
The specific embodiment
Embodiment 1
Get leaf of Acer Truncatum Buge 50kg, be ground into the big fractionlet of 1cm, add the 400kg distilled water 80 ℃ of lixiviates 2 hours, filter, filtering residue adds the 300kg distilled water again, and 80 ℃ of lixiviates 2 hours are filtered.Merging filtrate, adjustment pH value 8～9.5, deposition is removed non-utility, vacuum concentration, spray drying obtains the leaf of Acer Truncatum Buge extract flavone; Get Acer Truncatum Buge seed 30kg, through shelling handle, crude oil is produced, dewatering and filtering, low temperature are analysed layer, separating saturated fatty acid obtains the nervonic acid of Acer Truncatum Buge seed extract; Gained leaf of Acer Truncatum Buge and seed extract add the 10kg glucose powder, the 30g Mentholum, and the 80g Margarita powder, compounding, granulation, tabletting make finished product.
Embodiment 2
Leaf of Acer Truncatum Buge 50kg, being ground into the big fractionlet of 1cm, to add 400kg concentration be 40% ethanol, and 60 ℃ of lixiviates 2 hours are filtered, and adding 300kg concentration again is 70% ethanol, and 60 ℃ of lixiviates 2 hours are filtered.Merging filtrate.Ethanol is reclaimed in distillation, adds in the aqueous solution with volume solvent naphtha extraction secondary, and vacuum concentration, spray drying obtains the leaf of Acer Truncatum Buge extract flavone; Get Acer Truncatum Buge seed 30kg, through shelling handle, crude oil is produced, dewatering and filtering, low temperature are analysed layer, separating saturated fatty acid obtains the nervonic acid of Acer Truncatum Buge seed extract; Gained leaf of Acer Truncatum Buge and seed extract add 15kg xylitol, 15kg glucose, the 25g Mentholum, and the 200g calcium lactate, compounding, granulation, tabletting make finished product.
Claims (8)
1. Acer Truncatum Buge health care buccal tablets is characterized in that: process by following materials by weight percentage:
Leaf of Acer Truncatum Buge extract 20-40%
Acer Truncatum Buge seed extract 15-25%
Flavoring agent 30-64%
Nutrition enhancer 1-5%.
2. Acer Truncatum Buge health care buccal tablets according to claim 1 is characterized in that: said leaf of Acer Truncatum Buge extract is a flavone.
3. Acer Truncatum Buge health care buccal tablets according to claim 1 is characterized in that: said Acer Truncatum Buge seed extract is nervonic acid.
4. Acer Truncatum Buge health care buccal tablets according to claim 1 is characterized in that: said flavoring agent is a kind of or its any mixing of glucose, xylitol, Mentholum.
5. Acer Truncatum Buge health care buccal tablets according to claim 1 is characterized in that: said nutrition enhancer is calcium lactate or Margarita powder.
6. the method for preparing of the described Acer Truncatum Buge health care buccal tablets of claim 1 is characterized in that may further comprise the steps:
(1), the Acer Truncatum Buge seed through shelling handle, crude oil is produced, dewatering and filtering, low temperature are analysed layer, separating saturated fatty acid obtains the Acer Truncatum Buge seed extract: nervonic acid;
(2), leaf of Acer Truncatum Buge is through Screening Treatment, leaf pulverizing, lixiviate, filtration, macroporous resin adsorption separation, concentrating under reduced pressure, abstraction impurity removal, vacuum drying, pulverizing, obtains leaf of Acer Truncatum Buge extract: flavone;
(3), allocate step (1), (2) gained raw material into flavoring agent, nutrition enhancer, compounding is even, granulates, tabletting, makes finished product.
7. the method for preparing of Acer Truncatum Buge health care buccal tablets according to claim 6 is characterized in that: leaf is pulverized and is the big fractionlet of 1cm in the step (2).
8. the method for preparing of Acer Truncatum Buge health care buccal tablets according to claim 6; It is characterized in that: distilled water that the middle lixiviating solution of step (2) is 5～15 times of raw material consumptions or concentration expressed in percentage by volume content are 40～70% ethanol; Extraction temperature 60-80 ℃, extraction time 2-4 hour.
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| CN201210121141XA CN102614232A (en) | 2012-04-23 | 2012-04-23 | Acer truncatum health-care lozenge and preparation method thereof |
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| CN201210121141XA CN102614232A (en) | 2012-04-23 | 2012-04-23 | Acer truncatum health-care lozenge and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102813615A (en) * | 2012-08-25 | 2012-12-12 | 昆明海之灵生物科技开发有限公司 | Acer Trunctum Bunge Chinese medicinal herb lipstick and preparation method thereof |
| CN104587266A (en) * | 2015-02-05 | 2015-05-06 | 福州乾正药业有限公司 | Composition of nervonic acid and bamboo leaf flavonoid as well as preparation method and application thereof |
| CN105918587A (en) * | 2016-04-22 | 2016-09-07 | 江苏丹枫神源生物科技有限公司 | Acer truncatum seed oil tabletting candies and preparation method thereof |
| CN107874259A (en) * | 2017-12-28 | 2018-04-06 | 武汉天天好生物制品有限公司 | More oligopeptide mixtures of acer truncatum seed oil and preparation method thereof |
| CN108967797A (en) * | 2018-07-27 | 2018-12-11 | 张文晋 | A kind of food that demarcating neural acid content, high-content nervonic acid solid beverage and preparation method thereof |
| CN112293710A (en) * | 2020-10-29 | 2021-02-02 | 贾森 | Preparation method of composite micro-powder nutritional chewable tablet |
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| CN1524856A (en) * | 2003-09-15 | 2004-09-01 | 杨凌元宝枫生物制品有限公司 | Technology for extracting flavone from shoe-shaped maple leaves |
| CN1535710A (en) * | 2003-04-07 | 2004-10-13 | 王性炎 | Yuanbaofeng nervonic acid soft capsule and its preparation process |
| CN1537628A (en) * | 2003-10-22 | 2004-10-20 | 云南威达元宝枫产业开发有限公司 | Purpleblow maple lozenge for health-care,and its prepn. method |
| CN1557175A (en) * | 2004-02-12 | 2004-12-29 | 杨凌元宝枫生物制品有限公司 | Nervonic acid milk tablet making method |
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| CN1535710A (en) * | 2003-04-07 | 2004-10-13 | 王性炎 | Yuanbaofeng nervonic acid soft capsule and its preparation process |
| CN1524856A (en) * | 2003-09-15 | 2004-09-01 | 杨凌元宝枫生物制品有限公司 | Technology for extracting flavone from shoe-shaped maple leaves |
| CN1537628A (en) * | 2003-10-22 | 2004-10-20 | 云南威达元宝枫产业开发有限公司 | Purpleblow maple lozenge for health-care,and its prepn. method |
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| CN1557175A (en) * | 2004-02-12 | 2004-12-29 | 杨凌元宝枫生物制品有限公司 | Nervonic acid milk tablet making method |
| JP2010070487A (en) * | 2008-09-18 | 2010-04-02 | Fancl Corp | Mif secretion inhibitor |
| JP2010229062A (en) * | 2009-03-26 | 2010-10-14 | Fancl Corp | Bleaching agent |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102813615A (en) * | 2012-08-25 | 2012-12-12 | 昆明海之灵生物科技开发有限公司 | Acer Trunctum Bunge Chinese medicinal herb lipstick and preparation method thereof |
| CN102813615B (en) * | 2012-08-25 | 2014-04-30 | 昆明海之灵生物科技开发有限公司 | Acer Trunctum Bunge Chinese medicinal herb lipstick and preparation method thereof |
| CN104587266A (en) * | 2015-02-05 | 2015-05-06 | 福州乾正药业有限公司 | Composition of nervonic acid and bamboo leaf flavonoid as well as preparation method and application thereof |
| CN104587266B (en) * | 2015-02-05 | 2018-01-26 | 福州乾正药业有限公司 | The composition of nervonic acid and bamboo-leaves flavones, its preparation method and application |
| CN105918587A (en) * | 2016-04-22 | 2016-09-07 | 江苏丹枫神源生物科技有限公司 | Acer truncatum seed oil tabletting candies and preparation method thereof |
| CN107874259A (en) * | 2017-12-28 | 2018-04-06 | 武汉天天好生物制品有限公司 | More oligopeptide mixtures of acer truncatum seed oil and preparation method thereof |
| CN108967797A (en) * | 2018-07-27 | 2018-12-11 | 张文晋 | A kind of food that demarcating neural acid content, high-content nervonic acid solid beverage and preparation method thereof |
| CN112293710A (en) * | 2020-10-29 | 2021-02-02 | 贾森 | Preparation method of composite micro-powder nutritional chewable tablet |
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Application publication date: 20120801 |