CN102600449A - Traditional Chinese medicine damp-clearing and anti-diarrhea decoction for treating child autumn diarrhea - Google Patents
Traditional Chinese medicine damp-clearing and anti-diarrhea decoction for treating child autumn diarrhea Download PDFInfo
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- CN102600449A CN102600449A CN2012101128677A CN201210112867A CN102600449A CN 102600449 A CN102600449 A CN 102600449A CN 2012101128677 A CN2012101128677 A CN 2012101128677A CN 201210112867 A CN201210112867 A CN 201210112867A CN 102600449 A CN102600449 A CN 102600449A
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- 206010012735 Diarrhoea Diseases 0.000 title claims abstract description 30
- 239000003814 drug Substances 0.000 title claims abstract description 22
- 230000001142 anti-diarrhea Effects 0.000 title abstract 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 10
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 10
- 235000008434 ginseng Nutrition 0.000 claims abstract description 10
- 239000009636 Huang Qi Substances 0.000 claims abstract description 8
- 241001346334 Amomum tsao-ko Species 0.000 claims abstract description 3
- 210000000582 semen Anatomy 0.000 claims description 18
- 235000014347 soups Nutrition 0.000 claims description 11
- 241000208340 Araliaceae Species 0.000 claims description 9
- 240000008669 Hedera helix Species 0.000 claims description 9
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 9
- 241000545442 Radix Species 0.000 claims description 2
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 210000000952 spleen Anatomy 0.000 abstract description 6
- 238000010792 warming Methods 0.000 abstract description 5
- 210000004072 lung Anatomy 0.000 abstract description 3
- 240000000724 Berberis vulgaris Species 0.000 abstract 1
- 235000016068 Berberis vulgaris Nutrition 0.000 abstract 1
- 244000270834 Myristica fragrans Species 0.000 abstract 1
- 235000009421 Myristica fragrans Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 235000010580 Psophocarpus tetragonolobus Nutrition 0.000 abstract 1
- 240000003152 Rhus chinensis Species 0.000 abstract 1
- 235000014220 Rhus chinensis Nutrition 0.000 abstract 1
- 241000205578 Thalictrum Species 0.000 abstract 1
- 241000046198 Triteleia hyacinthina Species 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 7
- 230000013872 defecation Effects 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 5
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 208000010444 Acidosis Diseases 0.000 description 2
- 241000702670 Rotavirus Species 0.000 description 2
- 230000007950 acidosis Effects 0.000 description 2
- 208000026545 acidosis disease Diseases 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000001889 Acid-Base Imbalance Diseases 0.000 description 1
- 206010014418 Electrolyte imbalance Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 240000004859 Gamochaeta purpurea Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010020741 Hyperpyrexia Diseases 0.000 description 1
- 206010025476 Malabsorption Diseases 0.000 description 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 description 1
- 206010067470 Rotavirus infection Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 201000009840 acute diarrhea Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012109 statistical procedure Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 229940100050 virazole Drugs 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine damp-clearing and anti-diarrhea decoction for treating child autumn diarrhea which belongs to the field of diarrhoea in traditional Chinese medical science. The traditional Chinese medical science believes that insufficiency of the spleen with overabundance of dampness and deficiency-cold of middle burner are basic pathological characteristics of the disease. Thus, traditional Chinese medicines such as barberry, meadowrue root and rhizome, radix astragali, rhizoma atractylodis, poria cocos, white hyacinth bean, amomum tsao-ko, ginseng, Chinese gall, myristica fragrans and roasted ginger which have the functions of tonifying spleen and benefiting lung, clearing heat and expelling damp, and warming middle burner and stopping diarrhoea are selected to prepare the decoction. According to clinical tests in the hospital, the total effective rate achieves 96.5% and the time of stopping diarrhoea is obviously shorter than that of a control group, thus the decoction is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine eliminating dampness to stop diarrhea soup of treating infantile autumn diarrhea.
Background technology
Infantile autumn diarrhea is generally seen with rotavirus infection more, claims rotavirus enteritis again, and pilosity is born in autumn and winter season, good sending out in 6 months～2 years old infant; Being everlasting, it is bigger popular to cause annual autumn and winter, is that the common acute diarrhea of department of pediatrics is sick, and it is mainly through digestive tract or respiratory tract infection, and its pathology is that rotavirus is invaded small intestinal; Destroy intestinal mucosa fine hair, cause the hyperfunction and malabsorption of small intestinal peristalsis, this sick morbidity is anxious, progress is fast, and hyperpyrexia, vomiting are generally arranged; Thereafter diarrhoea occurs, stool is water sample or egg style, every day 5～10 times, even tens of times; Though this disease is a self-limited disease, if untimely treatment is prone to cause water, electrolyte and acid base imbalance; Dehydration and acidosis occur, influence children's upgrowth and development, even threat to life; Doctor trained in Western medicine lacks specific treatment clinically, and adopt suited the medicine to the illness and supporting treatment poor effect more.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine eliminating dampness to stop diarrhea soup of treating infantile autumn diarrhea.This disease belongs to the traditional Chinese medical science category of " having loose bowels ".The traditional Chinese medical science thinks that insufficiency of the spleen leading to overabundance of dampness, deficiency-cold in middle-JIAO are the basic pathology characteristics of primary disease, and for this reason, the traditional Chinese medical science is the rule of treatment with invigorating the spleen to benefit the lung, clearing heat and expelling damp, warming middle-JIAO to stop diarrhea.
The objective of the invention is to realize that through following technical scheme the Chinese medicine eliminating dampness to stop diarrhea soup of this treatment infantile autumn diarrhea is processed by following parts by weight of Chinese traditional medicine: Radix Berberidis Amurensis 10-15 part, Radix et Rhizoma Thalictri 10-15 part, Radix Astragali 9-11 part, Rhizoma Atractylodis 9-11 part, Poria 9-11 part, Semen Lablab Album 9-11 part, Fructus Tsaoko 9-11 part, Radix Ginseng 9-11 part, Galla Chinensis 8-10 part, Semen Myristicae 8-10 part, Rhizoma Zingiberis Preparatum 5-7 part.
Preferably, the Chinese medicine eliminating dampness to stop diarrhea soup of this treatment infantile autumn diarrhea is processed by following parts by weight of Chinese traditional medicine: 13 parts of Radix Berberidis Amurensis, 13 parts of Radix et Rhizoma Thalictri, 10 parts of the Radixs Astragali, 10 parts of Semen Lablab Albums, 10 parts in Poria, 10 parts of Fructus Tsaokos, 10 parts of Rhizoma Atractylodis, 10 parts of Radix Ginsengs, 9 parts of Galla Chinensiss, Semen Myristicae 9 minutes, 6 parts of Rhizoma Zingiberis Preparatums.
In the side: the Radix Astragali, Radix et Rhizoma Thalictri, Semen Lablab Album air making-up and spleen enlivening, dampness diuretic; Radix Berberidis Amurensis, Poria, Fructus Tsaoko, Rhizoma Atractylodis clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, spleen-benefiting mind-tranquilizing; The Radix Ginseng strongly invigorating primordial QI, invigorating the spleen to benefit the lung; Galla Chinensis, Semen Myristicae relieving diarrhea with astringents, warming middle-JIAO to promote flow of QI; The Rhizoma Zingiberis Preparatum warming the meridian for stopping bleeding, warming middle-JIAO to relieve pain.
Clinical data
1. 86 examples are organized in the physical data treatment, male 45 examples, women 41 examples, 10 months 6 months ages-2 years old.Hot person's 26 examples that occur together, vomiter's 32 examples, dehydrator 33 examples; Matched group 82 examples, male 42 examples, women 40 examples, 1 month 6 months age-2 years old, hot person's 22 examples that occur together, vomiter's 34 examples, dehydrator person 31 examples.Two groups of infant ages, sex, the course of disease, state of an illness do not have significant difference (P＜0.05) through statistical procedures, have comparability.
2. the standard formulated with reference to Chinese diarrhoeal diseases meeting of diagnostic criteria, produce effects: to take medicine 24-48 hour, times of defecation is reduced to≤and 2 times/day or return to normal number of times, the stool character recovers normal, the clinical symptoms complete obiteration; Effectively: to take medicine 48-72 hour, times of defecation just reduces to≤and 2 times/day, the stool character takes a turn for the better, and moisture obviously reduces, and clinical symptoms disappears basically; Invalid: took medicine back 72 hours, times of defecation still＞2 time/day or character do not have and be clearly better, even the state of an illness increases the weight of.
3. Therapeutic Method treatment group adopts the Chinese medicine eliminating dampness to stop diarrhea soup of treatment infantile autumn diarrhea of the present invention, Radix Berberidis Amurensis 13g, Radix et Rhizoma Thalictri 13g, Radix Astragali 10g, Semen Lablab Album 10g, Poria 10g, Fructus Tsaoko 10g, Rhizoma Atractylodis 10g, Radix Ginseng 10g, Galla Chinensis 9g, Semen Myristicae 9g, Rhizoma Zingiberis Preparatum 6g in the soup.Use water decoction, dosage:＜June, each 5m, June-1 years old, each 5-8ml; 1-3 year, each 8-10ml takes every day 3 times before the meal, and 7 days is a course of treatment.Matched group: virazole, dosage 10-15mg/kg/ day, divide 2 intramuscular injection or add in 10% glucose solution quiet, 7 days is a course of treatment.
4. criterion of therapeutical effect (1) produce effects: treated 3 days, times of defecation reduces one day 2 times or recovers normal number of times, and the stool character recovers normal, clinical symptom disappearance.(2) effective: treated 3 days, times of defecation is reduced to one day 3 times, and the stool character takes a turn for the better, and moisture obviously reduces, remission.(3) invalid: treat after 3 days times of defecation and still surpass 1 day 3 times, symptom does not have and is clearly better, even diarrhoea increases the weight of.
5. therapeutic outcome
Add up curative effect after treating two courses of treatment.Two groups of curative effects are relatively seen table 1
Table 1 liang group curative effect is [example (%)] relatively
Can find out that from table 1 treatment group total effective rate is 96.5%.The matched group total effective rate is 85.4%.Two groups of total effective rate comparing differences have remarkable statistical significance (p＜0.05), and the treatment group obviously is superior to matched group.
The infant clinical symptoms is improved situation (stool is normal, dehydration, acidosis are corrected, and spirit and appetite take a turn for the better) observe the curative effect, and is as shown in table 2.
P＜0.05。
The specific embodiment
Embodiment one: take by weighing Radix Berberidis Amurensis 13g, Radix et Rhizoma Thalictri 13g, Radix Astragali 10g, Semen Lablab Album 10g, Poria 10g, Fructus Tsaoko 10g, Rhizoma Atractylodis 10g, Radix Ginseng 10g, Galla Chinensis 9g, Semen Myristicae 9g, Rhizoma Zingiberis Preparatum 6g; Water decocts extracting juice after half an hour, and early, respectively obey 1 time evening, 7 days is 1 course of treatment.
Embodiment two: take by weighing Radix Berberidis Amurensis 15g, Radix et Rhizoma Thalictri 10g, Radix Astragali 9g, Semen Lablab Album 9g, Poria 9g, Fructus Tsaoko 9g, Rhizoma Atractylodis 9g, Radix Ginseng 9g, Galla Chinensis 8g, Semen Myristicae 8g, Rhizoma Zingiberis Preparatum 5g; Water decocts extracting juice after half an hour, and early, respectively obey 1 time evening, 7 days is 1 course of treatment.
Embodiment three: take by weighing Radix Berberidis Amurensis 10g, Radix et Rhizoma Thalictri 15g, Radix Astragali 11g, Semen Lablab Album 11g, Poria 11g, Fructus Tsaoko 11g, Rhizoma Atractylodis 11g, Radix Ginseng 11g, Galla Chinensis 10g, Semen Myristicae 10g, Rhizoma Zingiberis Preparatum 7g; Water decocts extracting juice after half an hour, and early, respectively obey 1 time evening, 7 days is 1 course of treatment.
Claims (2)
1. Chinese medicine eliminating dampness to stop diarrhea soup of treating infantile autumn diarrhea is characterized in that this Chinese medicine eliminating dampness to stop diarrhea soup processed by following parts by weight of Chinese traditional medicine: Radix Berberidis Amurensis 10-15 part, Radix et Rhizoma Thalictri 10-15 part, Radix Astragali 9--11 part, Rhizoma Atractylodis 9-11 part, Poria 9-11 part, Semen Lablab Album 9-11 part, Fructus Tsaoko 9-11 part, Radix Ginseng 9-11 part, Galla Chinensis 8-10 part, Semen Myristicae 8-10 part, Rhizoma Zingiberis Preparatum 5-7 part.
2. a kind of Chinese medicine eliminating dampness to stop diarrhea soup of treating infantile autumn diarrhea according to claim 1 is characterized in that this Chinese medicine eliminating dampness to stop diarrhea soup processed by following parts by weight of Chinese traditional medicine: 13 parts of Radix Berberidis Amurensis, 13 parts of Radix et Rhizoma Thalictri, 10 parts of the Radixs Astragali, 10 parts of Semen Lablab Albums, 10 parts in Poria, 10 parts of Fructus Tsaokos, 10 parts of Rhizoma Atractylodis, 10 parts of Radix Ginsengs, 9 parts of Galla Chinensiss, Semen Myristicae 9 minutes, 6 parts of Rhizoma Zingiberis Preparatums.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232694A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Traditional Chinese medicine for treating diarrhea, preparing method of traditional Chinese medicine for treating diarrhea and medicine product of traditional Chinese medicine for treating diarrhea |
| CN105232826A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Traditional Chinese medicinal composition for treating diarrhea, preparation method and medicine of traditional Chinese medicinal composition |
| CN105232689A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Antidiarrheal traditional Chinese medicine decoction for children and preparing method of antidiarrheal traditional Chinese medicine decoction |
| CN105267454A (en) * | 2015-10-29 | 2016-01-27 | 赵卫国 | Anti-diarrhea and spleen-tonifying decoction and preparation method thereof |
| CN105267492A (en) * | 2015-10-29 | 2016-01-27 | 赵卫国 | Anti-diarrhea traditional Chinese medicine decoction and preparation method thereof |
| CN106135582A (en) * | 2016-07-10 | 2016-11-23 | 杨在侠 | A kind of children's only diarrhoea Fructus Tsaoko tea |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102327590A (en) * | 2011-09-30 | 2012-01-25 | 荣成市崖头美全口腔诊所 | Traditional Chinese medicine composition for treating diarrhea |
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2012
- 2012-04-09 CN CN2012101128677A patent/CN102600449B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102327590A (en) * | 2011-09-30 | 2012-01-25 | 荣成市崖头美全口腔诊所 | Traditional Chinese medicine composition for treating diarrhea |
Non-Patent Citations (4)
| Title |
|---|
| 《中国中西医结合消化杂志》 20110430 张瑞清等 杨赶梅治疗小儿秋季泄泻临证经验 113-114 1-2 第19卷, 第2期 * |
| 《北京中医药大学学报》 19940131 田海河 董建华教授辨治泻痢五论 45-47 1-2 第17卷, 第1期 * |
| 张瑞清等: "杨赶梅治疗小儿秋季泄泻临证经验", 《中国中西医结合消化杂志》 * |
| 田海河: "董建华教授辨治泻痢五论", 《北京中医药大学学报》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232694A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Traditional Chinese medicine for treating diarrhea, preparing method of traditional Chinese medicine for treating diarrhea and medicine product of traditional Chinese medicine for treating diarrhea |
| CN105232826A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Traditional Chinese medicinal composition for treating diarrhea, preparation method and medicine of traditional Chinese medicinal composition |
| CN105232689A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Antidiarrheal traditional Chinese medicine decoction for children and preparing method of antidiarrheal traditional Chinese medicine decoction |
| CN105267454A (en) * | 2015-10-29 | 2016-01-27 | 赵卫国 | Anti-diarrhea and spleen-tonifying decoction and preparation method thereof |
| CN105267492A (en) * | 2015-10-29 | 2016-01-27 | 赵卫国 | Anti-diarrhea traditional Chinese medicine decoction and preparation method thereof |
| CN106135582A (en) * | 2016-07-10 | 2016-11-23 | 杨在侠 | A kind of children's only diarrhoea Fructus Tsaoko tea |
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| CN102600449B (en) | 2013-08-14 |
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