CN104127850A - Traditional Chinese medicine preparation for treating infantile diarrhea - Google Patents
Traditional Chinese medicine preparation for treating infantile diarrhea Download PDFInfo
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- CN104127850A CN104127850A CN201410389742.8A CN201410389742A CN104127850A CN 104127850 A CN104127850 A CN 104127850A CN 201410389742 A CN201410389742 A CN 201410389742A CN 104127850 A CN104127850 A CN 104127850A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating infantile diarrhea. The selected raw material medicines comprise the following components by weight: 20-30g of fried bighead atractylodes rhizome, 10-20g of amomum cardamomum, 10-20g of flos caryophylli, 10-20g of dried tangerine or orange peel, 10-20g of pepper, 10-20g of long pepper, 10-20g of Chinese yam, 10-20g of cinnamon, 8-12g of Radix Aconiti Praeparata, 8-15g of ginseng, 8-12g of baked ginger, 8-12g of fennel, 8-12g of fried medicated leaven and 8-12g of rhizoma corydalis. The medicines are high in compatibility and have the effects of warming kidney and invigorating spleen, regulating vital energy and supporting Yang, helping digestion and checking diarrhea, warming middle Jiao and relieving pain and stabilizing the intestinal tract and checking diarrhea, and the traditional Chinese medicine preparation is used for treating infantile diarrhea, has the advantages of fast effectiveness, short course of treatment, zero side effect and high cure rate and is worthy of clinical popularization and application.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation for the treatment of infantile diarrhea.
Background technology
Infantile diarrhea is by improper diet or the disorderly syndrome of the caused a kind of digestive tract function of the inside and outside infection of intestinal, the baby below 2 years old of mostly occurring.All may occur throughout the year, but maximum with summer and autumn.According to relevant statistics, the annual morbidity of 5 years old following diarrhea disease of inpatient children of China is 20.1%, falls ill each child's year 3.5 times every year on average, and its mortality rate is 0.51%.Therefore, very important to the control of infantile diarrhea disease.
The symptom that infantile diarrhea is lighter mostly is every day times of defecation below 10 times, and feces is yellow green, band mucus and be egg soup sample, and with slight abdominal distention, bowel sound hyperaction; When heavier, show as diarrhoea frequent, every day, tens of times of defecation, was water sample, amount is many, has acid smell, with galactorrhea or vomiting more.Severe patient is told coffee-like thing, with heating, irritated, drowsiness, dispirited, even goes into a coma, convulsions etc.; If the diarrhoea time is longer, the times of defecation of every day is more, and the comparatively serious complication such as dehydration, acidosis, electrolyte disturbance also can appear in some patients were.
Medicine, the method for modern medicine treatment infantile diarrhea have a lot.But the part that all comes with some shortcomings is not ideal enough.Though as conventional galactenzyme raw cook, Medilac-Vita, dioctahedral smectite have certain curative effect, the course for the treatment of is long, cure slowly; Doctor trained in Western medicine mainly adopts some antibiotics and naturopathy, though respite symptom is cured the symptoms, not the disease, and side effect is larger, easily infant health is caused to harmful effect.
Summary of the invention
The present invention has overcome at present in the technical deficiency existing aspect treatment infantile diarrhea, a kind of instant effect, short treating period is provided, has had no side effect and Chinese medicine preparation that cure rate is high.
The technical solution adopted in the present invention is: a kind of Chinese medicine preparation for the treatment of infantile diarrhea, it is characterized in that, and described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Atractylodis Macrocephalae preparata 20-30 gram, Fructus Amomi Rotundus 10-20 gram, Flos Caryophylli 10-20 gram, Pericarpium Citri Reticulatae 10-20 gram, Fructus Piperis 10-20 gram, Fructus Piperis Longi 10-20 gram, Rhizoma Dioscoreae 10-20 gram, Cortex Cinnamomi 10-20 gram, gun additioner 8-12 gram, Radix Ginseng 8-15 gram, Rhizoma Zingiberis Preparatum 8-12 gram, Fructus Foeniculi 8-12 gram, Massa Medicata Fermentata preparata 8-12 gram, Rhizoma Corydalis 8-12 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
20 grams of Rhizoma Atractylodis Macrocephalae preparatas, 10 grams of Fructus Amomi Rotunduss, 10 grams of Flos Caryophyllis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Fructus Piperis, 10 grams of Fructus Piperis Longi, 10 grams of Rhizoma Dioscoreaes, 10 grams of Cortex Cinnamomis, 8 grams of gun additioners, 8 grams of Radix Ginsengs, 8 grams of Rhizoma Zingiberis Preparatums, 8 grams of Fructus Foeniculi, 8 grams of Massa Medicata Fermentata preparatas, 8 grams of Rhizoma Corydalis.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
25 grams of Rhizoma Atractylodis Macrocephalae preparatas, 15 grams of Fructus Amomi Rotunduss, 15 grams of Flos Caryophyllis, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Fructus Piperis, 15 grams of Fructus Piperis Longi, 15 grams of Rhizoma Dioscoreaes, 15 grams of Cortex Cinnamomis, 10 grams of gun additioners, 12 grams of Radix Ginsengs, 10 grams of Rhizoma Zingiberis Preparatums, 10 grams of Fructus Foeniculi, 10 grams of Massa Medicata Fermentata preparatas, 10 grams of Rhizoma Corydalis.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
30 grams of Rhizoma Atractylodis Macrocephalae preparatas, 20 grams of Fructus Amomi Rotunduss, 20 grams of Flos Caryophyllis, 20 grams of Pericarpium Citri Reticulataes, 20 grams, Fructus Piperis, 20 grams of Fructus Piperis Longi, 20 grams of Rhizoma Dioscoreaes, 20 grams of Cortex Cinnamomis, 12 grams of gun additioners, 15 grams of Radix Ginsengs, 12 grams of Rhizoma Zingiberis Preparatums, 12 grams of Fructus Foeniculi, 12 grams of Massa Medicata Fermentata preparatas, 12 grams of Rhizoma Corydalis.
The instructions of taking of above-mentioned Chinese medicine preparation is: after the raw material Chinese medicine of above-mentioned weight proportion is mixed, get its medicine juice, 1 dose of every day, every day 3-4 time according to the method for the fried Chinese medicine of tradition.Consumption is 0-2 year, 10ml/ time; 2-4 year, 30ml/ time; 4-8 year, 50ml/ time; More than 8 years old, 80ml/ time.With disease plus-minus drug dose.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Rhizoma Atractylodis Macrocephalae preparata, bitter in the mouth, sweet, warm in nature; Return spleen, stomach warp.There is invigorating the spleen and benefiting QI, effect of dampness diuretic.
Fructus Amomi Rotundus, acrid in the mouth, warm in nature; Return lung, spleen, stomach warp.There is removing dampness circulation of qi promoting, effect of warming middle-JIAO to arrest vomiting.
Flos Caryophylli, acrid in the mouth, warm in nature; Return spleen, stomach, lung, kidney channel.There is warming middle-JIAO to send down the adverse QI, effect of reinforcing the kidney and supporting YANG.
Pericarpium Citri Reticulatae, acrid in the mouth, hardship, warm in nature; Return spleen, lung meridian.Having and regulating the flow of vital energy in tune, drying dampness to eliminate phlegm, effect of health-care.
Fructus Piperis, acrid in the mouth, warm in nature; Return stomach, large intestine channel.There is warming spleen and stomach for dispelling cold, effect of therapeutic method to keep the adverse QI flowing downwards expectorant.
Fructus Piperis Longi, acrid in the mouth is warm in nature; Return stomach, large intestine channel.There is effect of warming middle-JIAO to relieve pain.
Rhizoma Dioscoreae, sweet in the mouth, property are put down; Return spleen, lung, kidney channel.There is spleen reinforcing nourishing the stomach, effect of the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
Cortex Cinnamomi, acrid in the mouth, sweet, warm in nature; Return kidney, spleen, the heart, Liver Channel.There is the fire of benefit supporing yang, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian.
Gun additioner, acrid in the mouth, warm in nature; GUIXIN, spleen, kidney channel.Have recuperating depleted YANG and rescuing the patient from collapse, warming the interior is by cold, effect of antalgic.
Radix Ginseng, sweet in the mouth, micro-hardship, property is flat; Return spleen, lung, heart channel.Have strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, effect of promoting the production of body fluid and inducing sedation of the mind.
Rhizoma Zingiberis Preparatum, acrid in the mouth, warm in nature; Return spleen, stomach, kidney, the heart, lung meridian.There is warming spleen and stomach for dispelling cold, effect of warming the meridian for stopping bleeding.
Fructus Foeniculi, acrid in the mouth, warm in nature; Return liver,kidney,spleen, stomach warp.There is dispersing cold for relieving pain, effect of regulating qi-flowing for harmonizing stomach.
Massa Medicata Fermentata preparata, sweet in the mouth, pungent, warm in nature; Return spleen, stomach warp.There is invigorating the spleen and regulating the stomach, the effect helping digestion in adjusting.
Rhizoma Corydalis, acrid in the mouth, hardship, warm in nature; Return liver, stomach warp.There is promoting blood circulation to remove blood stasis, effect of promoting the circulation of QI to relieve pain.
Chinese medicine thinks that infant is the body of the young sun of young the moon, the liver being liable to excess, the spleen tending to insufficiency usually, being invaded by exogenous pathogen injures taste, so have loose bowels, thus treatment when taking spleen invigorating, nourishing the stomach, dispel cold, antidiarrheal is as principle.In Chinese medicine preparation of the present invention, Rhizoma Atractylodis Macrocephalae preparata, Massa Medicata Fermentata preparata can invigorating the spleen and regulating the stomach, in helping digestion and adjusting; During Fructus Amomi Rotundus, Pericarpium Citri Reticulatae can be regulated the flow of vital energy and be adjusted, drying dampness to eliminate phlegm; Flos Caryophylli, Fructus Piperis, Fructus Piperis Longi, Rhizoma Zingiberis Preparatum can warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain; Rhizoma Dioscoreae, Radix Ginseng can spleen reinforcing nourishing the stomach, and multiple arteries and veins is admittedly de-, righting primordial QI reinforcing; It is supporing yang that Cortex Cinnamomi, gun additioner can be mended fire, promoting the flow of QI-blood by warming the meridian; Rhizoma Corydalis, Fructus Foeniculi can regulating qi-flowing for harmonizing stomach, dispersing cold for relieving pain; All medicine compatibilities are superior, long memorial liver and qi altogether, and heat clearing awayization is stagnant; rush down clearly the effects such as dampness removing, cholagogic and lithagogue, after drug absorption; can defeated cloth whole body; make whole body meridian dredging, QI and blood smoothness, promote body recovery normal activity, promote digesting and assimilating of gastrointestinal; thereby reach warming spleen and stomach for dispelling cold; the spleen strengthening and damp drying, stomach function regulating helps digestion, the object of intestine-stabling and anti-diarrheal.
For further investigating clinical efficacy and the safety of medicine of the present invention, we select 78 routine Diarrheas to carry out clinical trial, are divided at random two groups, observation group's 39 examples, wherein male 21 examples, female's 18 examples, 6～36 months monthly ages, on average (20 ± 6) month, matched group 39 examples, wherein male 19 examples, female's 20 examples, 6～36 months monthly ages, average (19 ± 7) month.All cases stool outward appearance is all egg flower or rare water sample, and every day 5～16 times, stool microscopy is shown in Oil globule and leukocyte 58 examples, and accidental Oil globule or leukocyte 19 examples, without pus cell and erythrocyte.The aspect comparing difference not statistically significants (P > 0.05) such as two groups of infant body temperature, the course of disease, diarrhoea, degree of dehydration, have comparability.
Criterion of therapeutical effect (curative effect determinate standard of formulating with reference to national infantile diarrhea meeting in 1998):
Recovery from illness: in treatment 72h, every day, times of defecation recovered normal or every day 2 times, and stool character recovers normal, and General Symptoms and sign disappear;
Effective: in treatment 72h, times of defecation is obviously reduced to 1/3 before treatment or following, stool character was than improving in the past and moisture obviously reduces, and clinical symptoms sign disappears substantially;
Effective: in treatment 72h, it is front 1/2 that times of defecation is reduced to treatment, stool character is improved moisture minimizing, and clinical symptoms sign is obviously improved;
Invalid: in treatment 72h, times of defecation and character are without improvement, and clinical symptoms is almost without changing or increasing the weight of.
Therapeutic Method:
Treatment group is taken Chinese medicine preparation of the present invention, gets its medicine juice according to the method for the fried Chinese medicine of tradition, 1 dose of every day, every day 3-4 time.Consumption is 0-2 year, 10ml/ time; 2-4 year, 30ml/ time; 4-8 year, 50ml/ time; More than 8 years old, 80ml/ time.With disease plus-minus drug dose.The oral dioctahedral smectite of matched group, age-based 1/3-1 bag, 1 bu 3 times is taken, the age-based 1/2-1 bag of Medilac-Vita, 1 bu 3 times is taken.Be 3 days two groups of courses for the treatment of.
Symptomatic treatment: if infant body temperature exceedes 39 DEG C, continue the above person of 2h, can use nonsteroidal anti inflammatory antipyretic, can vein liquid make-up when high temperature continues.
Efficacy result:
After treatment, treatment group 13 examples of fully recovering, effective 15 examples, effective 10 examples, invalid 1 example, effective percentage is 97.4%; Matched group 8 examples of fully recovering, effective 10 examples, effective 13 examples, invalid 8 examples, effective percentage is 79.5%.Compared significant difference for two groups, the curative effect for the treatment of group is significantly better than matched group (P < 0.05).Detailed results is in table 1.
Table 1: the curative effect comparision result table after two groups of case treatments
| Group | Number of cases | Recovery from illness n (%) | Effective n (%) | Effectively n (%) | Invalid n (%) | Total effective rate (%) |
| Treatment group | 39 | 13(33.3) | 15(45.5) | 10(25.7) | 1(2.6) | 97.4 |
| Matched group | 39 | 8(20.5) | 10(25.7) | 13(33.3) | 8(20.5) | 79.5 |
Untoward reaction comparison:
During treating, all there is not obvious adverse reaction in two groups of patients.
Result shows, Chinese medicine preparation of the present invention can obviously shorten the infant course of disease, improve cure rate, and the method drug absorption is good, has no side effect, and infant and the head of a family are easy to accept, and is a kind for the treatment of by Chinese herbs method preferably, clinic promotion and application
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of infantile diarrhea, choose 20 grams of Rhizoma Atractylodis Macrocephalae preparatas, 10 grams of Fructus Amomi Rotunduss, 10 grams of Flos Caryophyllis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Fructus Piperis, 10 grams of Fructus Piperis Longi, 10 grams of Rhizoma Dioscoreaes, 10 grams of Cortex Cinnamomis, 8 grams of gun additioners, 8 grams of Radix Ginsengs, 8 grams of Rhizoma Zingiberis Preparatums, 8 grams of Fructus Foeniculi, 8 grams of Massa Medicata Fermentata preparatas, 8 grams of Rhizoma Corydalis.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of infantile diarrhea, choose 25 grams of Rhizoma Atractylodis Macrocephalae preparatas, 15 grams of Fructus Amomi Rotunduss, 15 grams of Flos Caryophyllis, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Fructus Piperis, 15 grams of Fructus Piperis Longi, 15 grams of Rhizoma Dioscoreaes, 15 grams of Cortex Cinnamomis, 10 grams of gun additioners, 12 grams of Radix Ginsengs, 10 grams of Rhizoma Zingiberis Preparatums, 10 grams of Fructus Foeniculi, 10 grams of Massa Medicata Fermentata preparatas, 10 grams of Rhizoma Corydalis.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of infantile diarrhea, choose 30 grams of Rhizoma Atractylodis Macrocephalae preparatas, 20 grams of Fructus Amomi Rotunduss, 20 grams of Flos Caryophyllis, 20 grams of Pericarpium Citri Reticulataes, 20 grams, Fructus Piperis, 20 grams of Fructus Piperis Longi, 20 grams of Rhizoma Dioscoreaes, 20 grams of Cortex Cinnamomis, 12 grams of gun additioners, 15 grams of Radix Ginsengs, 12 grams of Rhizoma Zingiberis Preparatums, 12 grams of Fructus Foeniculi, 12 grams of Massa Medicata Fermentata preparatas, 12 grams of Rhizoma Corydalis.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is further verified:
Case 1
Infant, man, 2 years old.Diarrhoea is for just completely mashed, folder milk lobe and mucus, and without pus and blood, spirit is more irritated, and it is slightly poor to react, and eyelid, anterior fontanelle have slight depression, xerocheilia, while crying, tear is few, and complexion is dark, has thirsty performance, and hospital diagnosis is moderate infantile diarrhea, treats three days effects little.Introduce through friend, take Chinese medicine preparation of the present invention and treat.Two days later, spirit is clearly better, and times of defecation reduces, and a night only 2 times, amount reduces, take to a course for the treatment of, and all transference cures, infant is in high spirits, cures.Follow up a case by regular visits to January without recurrence.
Case 2
Infant, female, 11 months.Because of fever, snivel, the aquiform stool of having loose bowels, 38 DEG C of body temperature, appetite, spiritual poor, accompanies the uneasiness of crying and screaming, and removes examination in hospital, is diagnosed as infantile diarrhea.Take galactenzyme raw cook treatment 2 days, DeGrain, the head of a family is burning with anxiety.Under friend's recommendation, take Chinese medicine preparation of the present invention and treat.Take after 1 dose, the number of times of having loose bowels reduces, and appetite, spirit are improved greatly, and sb.'s illness took a favorable turn, take after three days, and sign, transference cure, infant spirit is good, and examination in hospital is cured.Follow up a case by regular visits to January without recurrence.
Case 3
Infant, man, 1 years old.Generate heat 39 DEG C, approximately vomit 3-5 time every day, is gastric content, non-ejection, and the every day more than 10 of having loose bowels is inferior, is the rare aquiform stool of yellow, and egg soup sample, without mucus and pus and blood, without off-odor, occasionally has and tussiculas, and after morbidity, appetite is poor, and oliguria, is heavy diarrhoeal diseases by hospital diagnosis.Once had no improvement with neomycin treatment.Upon somebody's introduction, taking Chinese medicine preparation of the present invention treats.After the course for the treatment of, vomit the number of times normal that stops, suffers from diarrhoea, other symptom is improved greatly, continue to take after 2 days, and transference cure, examination in hospital indices is normal, rehabilitation.Follow up a case by regular visits to January without recurrence.
Case 4
Infant, man, 18 months.In August last year, diarrhoea companion's vomiting is in hospital 5 days, is diagnosed as infantile autumn diarrhea, and through doctor trained in Western medicine symptomatic treatment, heating is moved back, but infant still gushes water sample, odorless every day just more than ten times, Mental fatigue timidness due to deficiency of QI, and sob is faint, anorexia, father and mother are anxious.Taking upon somebody's introduction Chinese medicine preparation of the present invention treats.After 3 days, symptom is improved greatly, and the state of an illness alleviates; After 1 course for the treatment of, the equal nothing of all diseases, examination in hospital indices is normal, cures.Follow up a case by regular visits to January without recurrence.
Claims (4)
1. a Chinese medicine preparation for the treatment of infantile diarrhea, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Atractylodis Macrocephalae preparata 20-30 gram, Fructus Amomi Rotundus 10-20 gram, Flos Caryophylli 10-20 gram, Pericarpium Citri Reticulatae 10-20 gram, Fructus Piperis 10-20 gram, Fructus Piperis Longi 10-20 gram, Rhizoma Dioscoreae 10-20 gram, Cortex Cinnamomi 10-20 gram, gun additioner 8-12 gram, Radix Ginseng 8-15 gram, Rhizoma Zingiberis Preparatum 8-12 gram, Fructus Foeniculi 8-12 gram, Massa Medicata Fermentata preparata 8-12 gram, Rhizoma Corydalis 8-12 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the raw material of following weight portion:
20 grams of Rhizoma Atractylodis Macrocephalae preparatas, 10 grams of Fructus Amomi Rotunduss, 10 grams of Flos Caryophyllis, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Fructus Piperis, 10 grams of Fructus Piperis Longi, 10 grams of Rhizoma Dioscoreaes, 10 grams of Cortex Cinnamomis, 8 grams of gun additioners, 8 grams of Radix Ginsengs, 8 grams of Rhizoma Zingiberis Preparatums, 8 grams of Fructus Foeniculi, 8 grams of Massa Medicata Fermentata preparatas, 8 grams of Rhizoma Corydalis.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the raw material of following weight portion:
25 grams of Rhizoma Atractylodis Macrocephalae preparatas, 15 grams of Fructus Amomi Rotunduss, 15 grams of Flos Caryophyllis, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Fructus Piperis, 15 grams of Fructus Piperis Longi, 15 grams of Rhizoma Dioscoreaes, 15 grams of Cortex Cinnamomis, 10 grams of gun additioners, 12 grams of Radix Ginsengs, 10 grams of Rhizoma Zingiberis Preparatums, 10 grams of Fructus Foeniculi, 10 grams of Massa Medicata Fermentata preparatas, 10 grams of Rhizoma Corydalis.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the raw material of following weight portion:
30 grams of Rhizoma Atractylodis Macrocephalae preparatas, 20 grams of Fructus Amomi Rotunduss, 20 grams of Flos Caryophyllis, 20 grams of Pericarpium Citri Reticulataes, 20 grams, Fructus Piperis, 20 grams of Fructus Piperis Longi, 20 grams of Rhizoma Dioscoreaes, 20 grams of Cortex Cinnamomis, 12 grams of gun additioners, 15 grams of Radix Ginsengs, 12 grams of Rhizoma Zingiberis Preparatums, 12 grams of Fructus Foeniculi, 12 grams of Massa Medicata Fermentata preparatas, 12 grams of Rhizoma Corydalis.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106390077A (en) * | 2016-11-24 | 2017-02-15 | 慕长虹 | Pharmaceutical composition for treating stomachache and diarrhea and preparation method and application thereof |
-
2014
- 2014-07-31 CN CN201410389742.8A patent/CN104127850A/en active Pending
Non-Patent Citations (2)
| Title |
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| 庞国胜等: "《药到病除小绝招：一贴灵千家妙方》", 30 May 2014 * |
| 陈定忠: "附子理中丸加减治疗慢性腹泻35例", 《河南中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106390077A (en) * | 2016-11-24 | 2017-02-15 | 慕长虹 | Pharmaceutical composition for treating stomachache and diarrhea and preparation method and application thereof |
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