CN106390077A - Pharmaceutical composition for treating stomachache and diarrhea and preparation method and application thereof - Google Patents
Pharmaceutical composition for treating stomachache and diarrhea and preparation method and application thereof Download PDFInfo
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- CN106390077A CN106390077A CN201611044387.6A CN201611044387A CN106390077A CN 106390077 A CN106390077 A CN 106390077A CN 201611044387 A CN201611044387 A CN 201611044387A CN 106390077 A CN106390077 A CN 106390077A
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- Prior art keywords
- pharmaceutical composition
- diarrhoea
- parts
- stomachache
- cold
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 72
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- 239000003814 drug Substances 0.000 claims abstract description 17
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- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/235—Foeniculum (fennel)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a pharmaceutical composition for treating stomachache and diarrhea and a preparation method and application thereof. The pharmaceutical composition comprises, by weight, 3-20 parts of rhizoma zingiberis, 1-10 parts of pepper, 3-20 parts of pericarpium citri reticulatae, 1-10 parts of cortex cinnamomi and 3-20 parts of fennel. The pharmaceutical composition has the advantages that the pharmaceutical composition has effects of regulating qi and invigorating the stomach, warming the stomach to dispel cold and depressing qi, warming middle-jiao and restoring yang and can be used for treating diseases such as woman deficiency-cold dysmenorrhea, menstruation cold and impeded blood flow, amenorrhea, arthritis and lumbago, stomach duct and abdomen cold and pain, spleen-stomach deficiency and cold and qi stagnation, stomachache and diarrhea and loose stool and diarrhea caused by deficiency and cold. A preparation method of the pharmaceutical composition includes: evenly mixing the medicinal materials, crushing, and adding medicine auxiliaries to prepare the pharmaceutical composition. The preparation method is convenient, simple, easy to operate, suitable for batch production and wide application, and the like.
Description
Technical field
The present invention relates to pharmaceutical technology field, in particular to a kind of medicine treating the cold and cool stomachache causing, diarrhoea
Compositionss and preparation method thereof, particularly a kind of treat the cold and cool stomachache causing, the pharmaceutical composition and preparation method thereof of diarrhoea
And application.
Background technology
In daily life, a lot of people can cause stomachache, diarrhoea because of catching cold.For the traditional Chinese medical science, inside there is gastroenteropathy, be subject to outward
Cold stimulation, easily discomfort in many people., after cold stimulation, easily abdominal distention, warm in the people of particularly weakness of the spleen and stomach
The symptom such as gas, loose stool (times of defecation is many, and stool is shapeless), diarrhoea.
In addition, women is during menstrual period, lower abdomen or flank pain, or even the symptom of pain and waist sacrum easily occur.Especially
Be suffer from cold after, symptom aggravate.Severe patient with nausea and vomiting, dripping cold sweat, deadly cold hand and foot, or even can be fainted, to work and life
Bring impact.
For the above-mentioned symptom uncomfortable due to the cold and cool stomachache causing, diarrhoea even menstrual period, be typically only capable to rest, hot compress with
Reach the purpose of alleviation, not a kind of direct, therapy of specially good effect.
In view of this, the special proposition present invention.
Content of the invention
The first object of the present invention be to provide a kind of treat stomachache, the pharmaceutical composition of diarrhoea, with solve existing for
The cold and cool stomachache causing, diarrhoea and dysmenorrhea, described pharmaceutical composition has qi-regulating stomach invigorating, warming stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards warming middle-JIAO return
Positive the advantages of.For treating women's deficiency and coldness dysmenorrhea, through the cold disease such as stasis, amenorrhea, arthralgia due to cold lumbago, coldness and pain in the epigastrium；Can also be used for controlling
The diseases such as the Deficiency and coldness of spleen and stomach stagnation of QI, stomachache are had loose bowels, loose stool cold-dysentery.
The second object of the present invention is to provide a kind of described treatment stomachache, the preparation side of the pharmaceutical composition of diarrhoea
Method, the method will be pulverized after compositionss mix homogeneously, adds medical auxiliary materials to carry out preparation, obtains this treatment stomachache, the medicine of diarrhoea
Compositions, have the advantages that convenience, simple, easily operated, suitable batch production and extensively application.
The third object of the present invention is to provide a kind of described treatment stomachache, the application of the pharmaceutical composition of diarrhoea, should
Treatment stomachache, the pharmaceutical composition of diarrhoea are in preparation treatment people or animal due to the cold and cool stomachache causing, diarrhoea and dysmenorrhea
Application in medicine.
In order to realize the above-mentioned purpose of the present invention, spy employs the following technical solutions：
A kind of pharmaceutical composition treated stomachache, suffer from diarrhoea, including following component in parts by weight：
3～20 parts of Rhizoma Zingiberiss, 1～10 part of Fructus Piperiss, 3～20 parts of Pericarpium Citri Reticulatae, 1～10 part of Cortex Cinnamomi and 3～20 parts of Fructus Foeniculi.
Rhizoma Zingiberiss, are the dry rhizome of zingiber.Acrid in the mouth, property heat.Enter the heart, lung, spleen, stomach.There is warming spleen and stomach for dispelling cold, return
Sun is promoted blood circulation, the effect of warming the lung to resolve fluid-retention.Can be used for treating coldness and pain in the epigastrium, vomiting is had loose bowels, cold weak pulse of limb, cold fluid-retention are breathed with cough.Rhizoma Zingiberiss have
There is warming spleen and stomach for dispelling cold, for taste cold syndrome, symptoms include coldness and pain in the epigastrium, vomiting is had loose bowels etc..Rhizoma Zingiberiss are hot dry strong, and master enters taste and is longer than temperature
Middle cold expelling, strong activating the spleen sun, all taste cold syndrome, the excess syndrome no matter invaded in exogenous cold, or the deficiency syndrome of YANG QI deficiency are all applicable.If stomach vomiting due to pathogenic cold
Tell, coldness and pain in the epigastrium, use cooperatively with Rhizoma Alpiniae Officinarum.
Fructus Piperiss acrid in the mouth, property heat.Return stomach, large intestine channel.There is the effect of warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.Can be used for treating abdomen
Pain have loose bowels, inappetence, the disease of epilepsy abundant expectoration.There are the functions such as calmness, warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, stomach invigorating, pain relieving, antiinflammatory, removing toxic substances.
Modern study, Fructus Piperiss Central nervous system has inhibitory action, and contained piperine can extend pentobarbital rat
The length of one's sleep, and play the role of substantially to resist pentetrazole convulsions and resist electric convulsive effect；Fructus Piperiss and piperine have promotion gallbladder
The effect of juice secretion；Piperine all has inhibitory action to various acute and chronic inflammatory disease；Piperine also has the effect of raising blood pressure.
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Pericarpium Citri tangerinae dispelling the damp pathogen with bitter and warm drugs
And energy spleen invigorating circulation of qi promoting, therefore it is usually used in the diseases such as retention of dampness in middle-JIAO, gastral cavity abdomen feeling of distension and oppression, loose stool greasy fur.
Fructus Foeniculi, the dry mature fruit of samphire Fructus Foeniculi.Acrid in the mouth, warm in nature.Return liver,kidney,spleen, stomach.Fructus Foeniculi
There are dispersing cold for relieving pain, effect of regulating qi-flowing for harmonizing stomach.Fructus Foeniculi all has for cold hernia stomachache, dysmenorrhea, few abdomen crymodynia, abdominal distention very well
Curative effect.
Fructus Foeniculi acrid in the mouth, warm in nature, there is dispersing cold for relieving pain, regulating the stomach to normalize QI.Modern pharmacological research shows, Fructus Foeniculi is also
There are antiulcer, analgesia, gonadotropic Effect etc., Oleum Anisi Stellati has different degrees of antibacterial action.
Cortex Cinnamomi, is the dry bark of canella Cortex Cinnamomi.Acrid in the mouth, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.Benefit fire is had to help
Sun, guiding fire to origin, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian.Can be used for sexual impotence cold womb, chills and pain of the waist and kness, kidney deficiency is breathed heavily, on empty sun
Floating, dizziness conjunctival congestion, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold hernia stomachache, dysmenorrhea amenorrhea.
Treatment stomachache provided herein and the pharmaceutical composition of diarrhoea, can be with effectively treatment women's deficiency and coldness dysmenorrhea, warp
The diseases such as cold stasis, amenorrhea, arthralgia due to cold lumbago, coldness and pain in the epigastrium；Can be also used for controlling the Deficiency and coldness of spleen and stomach stagnation of QI, stomachache is had loose bowels, loose stool cold-dysentery
Deng disease.Qi-regulating stomach invigorating, warming stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards warming middle-JIAO recuperating depleted YANG.Have loose bowels in the especially cold and cool dysmenorrhea causing, stomachache, loose stool.Its
In, in the range of set number, collocation uses above-mentioned Chinese medicine, has the work(of pain more than treatment Deficiency and coldness of spleen and stomach, cold, the umbilicuss abdomen of timid cold fear
Effect.
Preferably, the pharmaceutical composition that described treatment is suffered from abdominal pain, suffered from diarrhoea, including following component in parts by weight：
3～15 parts of Rhizoma Zingiberiss, 1～8 part of Fructus Piperiss, 3～15 parts of Pericarpium Citri Reticulatae, 1～5 part of Cortex Cinnamomi and 3～10 parts of Fructus Foeniculi.
The component of above-mentioned treatment stomachache, the pharmaceutical composition of diarrhoea can be carried out preferably.
Preferably, the pharmaceutical composition that described treatment is suffered from abdominal pain, suffered from diarrhoea, including following component in parts by weight：
5～10 parts of Rhizoma Zingiberiss, 2～6 parts of Fructus Piperiss, 5～10 parts of Pericarpium Citri Reticulatae, 2～4 parts of Cortex Cinnamomi and 5～8 parts of Fructus Foeniculi.
The component of above-mentioned treatment stomachache, the pharmaceutical composition of diarrhoea can be carried out further preferred.
Preferably, described Fructus Piperiss include one of black pepper and Radix orixae japonicae or two kinds of combination, and described Pericarpium Citri Reticulatae includes
One of Pericarpium Citri tangerinae and Pericarpium Citri Reticulatae Viride or two kinds.
The main component of Fructus Piperiss is piperine, also contains a certain amount of aromatic oil, crude protein, crude fat and soluble nitrogen,
Can dispel raw meat, solution greasy, aid digestion；The abnormal smells from the patient energy appetite stimulator of Fructus Piperiss；Fructus Piperiss heat warm in nature, to the stomach abdomen cold type of pain caused by cold syndrome of the stomach, intestinal
Ring diarrhoea has good mitigation, and treats anemofrigid cold；Fructus Piperiss play the role of antiseptic and inhibiting bacteria function；Wherein, the pungent of black pepper
Stronger than Radix orixae japonicae, and the medical value of Radix orixae japonicae is larger, can cold expelling, stomach invigorating etc., antiperspirant can be inspired with appetite stimulator, aid digestion；
Women leucorrhea abnormal and epilepsy can also be improved.
Pericarpium Citri Reticulatae is divided into Pericarpium Citri tangerinae and two kinds of Pericarpium Citri Reticulatae Viride.Wherein, Pericarpium Citri tangerinae is warm in nature, and acrid in the mouth is bitter, enters spleen, lung meridian.According to surveying and determination, containing more
Volatile oil, predominantly limonene, isopropenyl toluene, oxalene etc., separately contain Hesperidin, cis coumarin, Radix Dauci Sativae in peel
The compositions such as element, cryptoxanthine, vitamin B1, vitamin C, have functions that qi-regulating, adjust in, dampness, resolving sputum, be usually used in treat chest and abdomen
The diseases such as distension, anorexia, the dirty inverse, cough with copious phlegm of vomiting.Modern pharmacological research confirms, the Hesperidin contained by Pericarpium Citri Reticulatae can increase blood
Flow, the vasoconstriction that antagonism epinephrine causes, there is dilating effect to coronary vasodilator, and may act on vascular smooth muscle, have
Slow hypotensive effect；The effective ingredient such as contained cis coumarin have antiinflammatory, antiulcer and choleretic effect, are spleen invigorating circulation of qi promoting
Common medicine.
Pericarpium Citri Reticulatae Viride slightly warm in nature, bitter is pungent, enter liver, gallbladder meridian, there is soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant, be usually used in treating breast
The diseases such as side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.
To sum up, Pericarpium Citri Reticulatae and Pericarpium Citri Reticulatae Viride are all QI regulating medicine, but Pericarpium Citri Reticulatae is gentler, partially enters spleen and lung edema caused by disorder of QI, and can drying dampness to eliminate phlegm；Blue or green
Skin is higher strong, inclined enter liver gallbladder meridian, and circulation of qi promoting effect is relatively strong, energy catharsis liver and gall, dispelling the stagnated QI removing food stagnancy.Pericarpium Citri Reticulatae manages QI of the spleen and stomach, dampness
Expectorant；Pericarpium Citri Reticulatae Viride manages irritability, and removing food stagnancyization is stagnant, although both effects are different, may be used to treatment stomachache provided herein,
The pharmaceutical composition of diarrhoea.
Preferably, in terms of mass fraction, also include：Rhizoma Alpiniae Officinarum 1-3 part.
Rhizoma Alpiniae Officinarum, calls little Rhizoma Alpiniae Officinarum, Rhizoma Alpiniae Officinarum, is the ecology of zingiberaceous plant base material, perennial herb.Rhizoma Alpiniae Officinarum has pungent
Dissipate warm logical, effect of dispersing cold for relieving pain.
Preferably, described pharmaceutical composition also includes medical auxiliary materials；
It is furthermore preferred that the dosage form of described pharmaceutical composition is non-intestinal drug delivery agent；It is further preferred that described non-bowel
Drug-delivery preparation includes spray and patch.
Treatment stomachache provided herein, the pharmaceutical composition of diarrhoea, can within use, also can external.The outer used time, preparation
After be affixed at umbilicuss, umbilicuss are the scar tissues being formed after umbilical cord is cut off after fetal birth, by Qizhong (i.e. " SHENQUE acupoint ")
Implement the treatment meanss such as moxa-moxibustion, point-application, cup, to reach promoting flow of QI and blood, to adjust the purpose of negative and positive, treatment disease.Should
Pharmaceutical composition is affixed at umbilicuss, can get twice the result with half the effort with effectively treatment because having loose bowels in the cold and cool dysmenorrhea causing, stomachache, loose stool,
And it is easy to use.
Treatment stomachache as above, the preparation method of the pharmaceutical composition of diarrhoea, comprise the following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are pulverized respectively, grinding and sieving, carry out after sieving mixing, preparation,
Obtain this treatment stomachache, the pharmaceutical composition of diarrhoea.
Treatment provided herein is suffered from abdominal pain, the preparation method of the pharmaceutical composition of diarrhoea, due to the size of various Chinese medicines
Differ, pulverize the granule after contributing to pulverizing respectively uniformly, mix homogeneously, after contributing to preparation, various composition uniformly plays medicine
Effect.The method has the advantages that convenience, simple, easily operated, suitable batch production and extensively application.
Preferably, described pulverizing is carried out using pulverizer.
Pulverizing can improve the efficiency of pulverizing, improves the uniformity coefficient of Chinese medicine after pulverizing.
Preferably, described sieve specially 4～40 mesh sieves.
The purpose sieved be allow pulverize after Chinese medicine particle diameter equal as far as possible.
Treatment stomachache as above, the pharmaceutical composition of diarrhoea are caused due to cold and cool in preparation treatment people or animal
Application in the medicine of stomachache, diarrhoea and dysmenorrhea.
Compared with prior art, beneficial effects of the present invention are：
1), the pharmaceutical composition that treatment provided herein is suffered from abdominal pain, suffered from diarrhoea, has qi-regulating stomach invigorating, warming stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards
The advantages of warming middle-JIAO recuperating depleted YANG.
2), the pharmaceutical composition that treatment provided herein is suffered from abdominal pain, suffered from diarrhoea, for treating women's deficiency and coldness dysmenorrhea, through cold
The diseases such as stasis, amenorrhea, arthralgia due to cold lumbago, coldness and pain in the epigastrium；For controlling the Deficiency and coldness of spleen and stomach stagnation of QI, stomachache is had loose bowels, the disease such as loose stool cold-dysentery.
3), treatment stomachache provided herein, the preparation method of the pharmaceutical composition of diarrhoea, by compositionss mix homogeneously
After pulverize, add medical auxiliary materials to carry out preparation, obtain this treatment stomachache, the pharmaceutical composition of diarrhoea, have conveniently, simple, easily
The advantages of operation, it is suitable for batch production and extensively applies.
4) treatment stomachache, provided herein, the pharmaceutical composition of diarrhoea treat people or animal due to cold in preparation
Application in the medicine of the cool stomachache causing, diarrhoea and dysmenorrhea.
Specific embodiment
Below in conjunction with embodiment, embodiment of the present invention is described in detail, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and be not construed as limiting the scope of the present invention.Unreceipted concrete in embodiment
Condition person, the condition according to normal condition or manufacturer's suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, are
Can be by the commercially available conventional products bought and obtain.
Embodiment 1
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 3g, Fructus Piperiss 1g, Pericarpium Citri Reticulatae 3g, Cortex Cinnamomi 1g, Rhizoma Alpiniae Officinarum and Fructus Foeniculi 3g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are respectively adopted pulverizer pulverized, grinding and sieving, then mix
Close, glue wafer, obtain this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 2
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 20g, Fructus Piperiss 10g, Pericarpium Citri Reticulatae 20g, Cortex Cinnamomi 10g, Rhizoma Alpiniae Officinarum and Fructus Foeniculi 20g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are respectively adopted pulverizer pulverized, after pulverizing, cross the sieve of 4 mesh
Son, then mixes, pill agent, obtains this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 3
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 20g, Fructus Piperiss 10g, Pericarpium Citri Reticulatae 20g, Cortex Cinnamomi 10g and Fructus Foeniculi 20g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are respectively adopted pulverizer pulverized, after pulverizing, cross the sieve of 40 mesh
Son, then mixes, patch processed, obtains this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 4
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 5g, Fructus Piperiss 2g, Pericarpium Citri Reticulatae 5g, Cortex Cinnamomi 2g and Fructus Foeniculi 5g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are respectively adopted pulverizer pulverized, after pulverizing, cross the sieve of 40 mesh
Son, then mixes, patch processed, obtains this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 5
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 10g, Fructus Piperiss 6g, Pericarpium Citri Reticulatae 10g, Cortex Cinnamomi 4g and Fructus Foeniculi 8g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are respectively adopted pulverizer pulverized, after pulverizing, cross the sieve of 20 mesh
Son, then mixes, patch processed, obtains this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 6
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 12g, Fructus Piperiss 5g, Pericarpium Citri Reticulatae 12g, Cortex Cinnamomi 3g and Fructus Foeniculi 12g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are respectively adopted pulverizer pulverized, after pulverizing, cross the sieve of 10 mesh
Son, then mixes, patch processed, obtains this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 7
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 5g, Radix orixae japonicae 1g, Pericarpium Citri Reticulatae 3g, Cortex Cinnamomi 1g, Rhizoma Alpiniae Officinarum 1g and Fructus Foeniculi 3g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Radix orixae japonicae, Pericarpium Citri Reticulatae (Pericarpium Citri tangerinae), Cortex Cinnamomi, Rhizoma Alpiniae Officinarum and Fructus Foeniculi are respectively adopted pulverizer and are pulverized, pulverizes
Cross the sieve of 10 mesh afterwards, then mix, oral liquid processed, obtain this treatment stomachache, the pharmaceutical composition of diarrhoea.
Embodiment 8
The treatment that the present embodiment is provided is suffered from abdominal pain, the pharmaceutical composition of diarrhoea, including following component：
Rhizoma Zingiberiss 18g, black pepper 5g, Pericarpium Citri Reticulatae 5g, Cortex Cinnamomi 5g, Rhizoma Alpiniae Officinarum 3g and Fructus Foeniculi 5g.
The preparation method of this pharmaceutical composition, specifically includes following steps：
Rhizoma Zingiberiss, Radix orixae japonicae, Pericarpium Citri Reticulatae Viride, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum and Fructus Foeniculi are respectively adopted pulverizer pulverized, after pulverizing, cross 20
Purpose sieve, then mixes, patch processed, obtains this treatment stomachache, the pharmaceutical composition of diarrhoea.
Experimental example case
Case 1 admires certain, female, when 15 years old during menarche, dysmenorrhea especially severe, and take five pairs of decoction for warming channelss, there is no effect, adopt
The patch being provided with the embodiment of the present application 3, is affixed at umbilicuss, and reusable heat water bag temperature is applied, and applies every time 20 minutes, treatment in two days
Journey, after a course for the treatment of, menstrual period are painless again.
Case 2 gold medal, female, 18 years old, Korean nationality, due to living habit, often contact cold water and do not wear socks, menstrual period are often felt
Stomachache, the patch being provided using the embodiment of the present application 4, it is affixed at umbilicuss, reusable heat water bag temperature is applied, deposited 20 minutes every time, two
Its course for the treatment of, after a course for the treatment of, menstrual period are painless again.
Case 3 Wang, female, 45 years old, cause diarrhoea due to catching a cold, watery stool, in the case of not taking any medicine,
The patch being provided using the embodiment of the present application 5, is affixed at umbilicuss, and reusable heat water bag temperature is applied, and after 20 minutes, stomachache disappears, abdomen
Rush down healing.
Case 4 Pan, man, 2 years old, diarrhoea, spumescence watery stool, the patch being provided using the embodiment of the present application 6, it is affixed on
At umbilicuss, reusable heat water bag temperature is applied, and after 20 minutes, stomachache disappears, and diarrhoea is cured.
Case 5 Lee, female 23 years old, people from Hubei.Abdominal pain in menstruation, examination in hospital result is normally, and living habit is the winter
It, through conventional cold water laundry clothes, foot bath, is belonged to deficiency and coldness dysmenorrhea, the symptom through cold stasis, is provided using the embodiment of the present application 3
Patch, is affixed at umbilicuss, and reusable heat water bag temperature is applied, and during menstrual period, once a day, 20 minutes every time, continues two menstrual period, after treatment
Menstrual period painless warp again, does not recur.
In sum, the pharmaceutical composition that treatment provided herein is suffered from abdominal pain, suffered from diarrhoea, has qi-regulating stomach invigorating, stomach warming dissipates
Cold, effect of therapeutic method to keep the adverse QI flowing downwards warming middle-JIAO recuperating depleted YANG.Can be used for treating women's deficiency and coldness dysmenorrhea, cold through cold stasis, amenorrhea, arthralgia due to cold lumbago, gastral cavity abdomen
The diseases such as pain；For controlling the Deficiency and coldness of spleen and stomach stagnation of QI, stomachache is had loose bowels, the disease such as loose stool cold-dysentery.But, all overabundance of YANG leading to deficiency of YIN, hyperactivity of fire caused by deficiency of YIN person, pregnant
Woman ought avoid use.While treatment, avoid cold and cool, and eat raw and cold food.Treatment provided herein is suffered from abdominal pain, the drug regimen of diarrhoea
The preparation method of thing, will pulverize after compositionss mix homogeneously, adds medical auxiliary materials to carry out preparation, obtain this treatment stomachache, diarrhoea
Pharmaceutical composition, have the advantages that conveniently, simple, easily operated, be suitable for batch production and extensive apply.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's
Many other changes can be made in the case of spirit and scope and change.It is, therefore, intended that in the following claims
Including all such changes and modifications belonging in the scope of the invention.
Claims (10)
1. a kind of pharmaceutical composition treating stomachache, diarrhoea is it is characterised in that include following component in parts by weight：
3～20 parts of Rhizoma Zingiberiss, 1～10 part of Fructus Piperiss, 3～20 parts of Pericarpium Citri Reticulatae, 1～10 part of Cortex Cinnamomi and 3～20 parts of Fructus Foeniculi.
2. treatment stomachache according to claim 1, the pharmaceutical composition of diarrhoea are it is characterised in that include according to weight portion
The following component of number meter：
3～15 parts of Rhizoma Zingiberiss, 1～8 part of Fructus Piperiss, 3～15 parts of Pericarpium Citri Reticulatae, 1～5 part of Cortex Cinnamomi and 3～10 parts of Fructus Foeniculi.
3. treatment stomachache according to claim 1, the pharmaceutical composition of diarrhoea are it is characterised in that include according to weight portion
The following component of number meter：
5～10 parts of Rhizoma Zingiberiss, 2～6 parts of Fructus Piperiss, 5～10 parts of Pericarpium Citri Reticulatae, 2～4 parts of Cortex Cinnamomi and 5～8 parts of Fructus Foeniculi.
4. the treatment stomachache according to any one of claim 1-3, the pharmaceutical composition of diarrhoea are it is characterised in that described Hu
Green pepper includes one of black pepper and Radix orixae japonicae or two kinds of combination, described Pericarpium Citri Reticulatae include one of Pericarpium Citri tangerinae and Pericarpium Citri Reticulatae Viride or
Two kinds.
5. the pharmaceutical composition for the treatment of stomachache according to claim 4, diarrhoea is it is characterised in that in terms of mass fraction, go back
Including：Rhizoma Alpiniae Officinarum 1-3 part.
6. the treatment stomachache according to any one of claim 1-5, the pharmaceutical composition of diarrhoea are it is characterised in that described medicine
Compositions also include medical auxiliary materials；
Preferably, the dosage form of described pharmaceutical composition is oral Preparation or non-intestinal drug delivery agent；Preferably, described oral
Drug-delivery preparation includes powder, tablet, capsule, granule, pill and oral liquid；Preferably, described non-intestinal drug delivery agent bag
Include spray and patch.
7. the treatment stomachache according to any one of claim 1-5, the preparation method of the pharmaceutical composition of diarrhoea, its feature exists
In comprising the following steps：
Rhizoma Zingiberiss, Fructus Piperiss, Pericarpium Citri Reticulatae, Cortex Cinnamomi and Fructus Foeniculi are pulverized respectively, grinding and sieving, carry out after sieving mixing, preparation, obtain
This treatment stomachache, the pharmaceutical composition of diarrhoea.
8. treatment stomachache according to claim 7, the preparation method of the pharmaceutical composition of diarrhoea are it is characterised in that described
Pulverize and carried out using pulverizer.
9. treatment stomachache according to claim 7, the preparation method of the pharmaceutical composition of diarrhoea are it is characterised in that described
Sieve specially 4～40 mesh sieves.
10. the pharmaceutical composition treating stomachache, diarrhoea according to any one of claim 1-5 is treated people in preparation or is moved
Thing is due to the application in the medicine of the cold and cool stomachache causing, diarrhoea and dysmenorrhea.
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| CN111346202A (en) * | 2018-12-21 | 2020-06-30 | 杭州高德健洲生物科技有限公司 | Traditional Chinese medicine composition and preparation method and application thereof |
| CN112245557A (en) * | 2020-10-23 | 2021-01-22 | 迟金湘 | External ointment for warming and invigorating yang qi, dispelling wind and cold and relieving pain and preparation method thereof |
| CN112675280A (en) * | 2021-01-14 | 2021-04-20 | 韦燕玲 | Composition for preventing and treating carsickness and preparation method thereof |
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