CN102599182B - Insecticidal composition and application thereof - Google Patents
Insecticidal composition and application thereof Download PDFInfo
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- CN102599182B CN102599182B CN201210046705.8A CN201210046705A CN102599182B CN 102599182 B CN102599182 B CN 102599182B CN 201210046705 A CN201210046705 A CN 201210046705A CN 102599182 B CN102599182 B CN 102599182B
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- indoxacarb
- piperazine worm
- pyridine
- worm pyridine
- suspending agent
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- 239000000203 mixture Substances 0.000 title claims abstract description 29
- 230000000749 insecticidal effect Effects 0.000 title abstract description 7
- 239000005907 Indoxacarb Substances 0.000 claims abstract description 112
- VBCVPMMZEGZULK-NRFANRHFSA-N indoxacarb Chemical compound C([C@@]1(OC2)C(=O)OC)C3=CC(Cl)=CC=C3C1=NN2C(=O)N(C(=O)OC)C1=CC=C(OC(F)(F)F)C=C1 VBCVPMMZEGZULK-NRFANRHFSA-N 0.000 claims abstract description 112
- 241001414720 Cicadellidae Species 0.000 claims abstract description 38
- 241001122767 Theaceae Species 0.000 claims abstract description 38
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 claims description 201
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 200
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 100
- 239000000375 suspending agent Substances 0.000 claims description 36
- 230000000361 pesticidal effect Effects 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 7
- 238000009736 wetting Methods 0.000 claims description 7
- 239000000839 emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 238000009472 formulation Methods 0.000 claims description 4
- 239000004615 ingredient Substances 0.000 claims description 4
- XVMSFILGAMDHEY-UHFFFAOYSA-N 6-(4-aminophenyl)sulfonylpyridin-3-amine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=N1 XVMSFILGAMDHEY-UHFFFAOYSA-N 0.000 claims 1
- 125000004193 piperazinyl group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 31
- 230000002195 synergetic effect Effects 0.000 abstract description 20
- 241000607479 Yersinia pestis Species 0.000 abstract description 5
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000000447 pesticide residue Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 description 40
- 239000002131 composite material Substances 0.000 description 17
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- 230000000694 effects Effects 0.000 description 12
- 235000009024 Ceanothus sanguineus Nutrition 0.000 description 10
- 240000003553 Leptospermum scoparium Species 0.000 description 10
- 235000015459 Lycium barbarum Nutrition 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- 230000002045 lasting effect Effects 0.000 description 9
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 8
- 241000238631 Hexapoda Species 0.000 description 8
- 231100000419 toxicity Toxicity 0.000 description 8
- 230000001988 toxicity Effects 0.000 description 8
- 239000002270 dispersing agent Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000000575 pesticide Substances 0.000 description 5
- 239000011734 sodium Substances 0.000 description 5
- 229910052708 sodium Inorganic materials 0.000 description 5
- 239000000080 wetting agent Substances 0.000 description 5
- 229920001285 xanthan gum Polymers 0.000 description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 125000002877 alkyl aryl group Chemical group 0.000 description 4
- 239000000306 component Substances 0.000 description 4
- 238000000227 grinding Methods 0.000 description 4
- 239000002917 insecticide Substances 0.000 description 4
- 150000004002 naphthaldehydes Chemical class 0.000 description 4
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 4
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 4
- 239000003905 agrochemical Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 241000086608 Empoasca vitis Species 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229960001760 dimethyl sulfoxide Drugs 0.000 description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000002569 neuron Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- KXGFMDJXCMQABM-UHFFFAOYSA-N 2-methoxy-6-methylphenol Chemical compound [CH]OC1=CC=CC([CH])=C1O KXGFMDJXCMQABM-UHFFFAOYSA-N 0.000 description 1
- QMEQBOSUJUOXMX-UHFFFAOYSA-N 2h-oxadiazine Chemical compound N1OC=CC=N1 QMEQBOSUJUOXMX-UHFFFAOYSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
- 241001674939 Caulanthus Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000001293 FEMA 3089 Substances 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 241000819999 Nymphes Species 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 108010052164 Sodium Channels Proteins 0.000 description 1
- 102000018674 Sodium Channels Human genes 0.000 description 1
- -1 Sodium alkyl benzene Chemical class 0.000 description 1
- 241000176086 Sogatella furcifera Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 229940077388 benzenesulfonate Drugs 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 230000006727 cell loss Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000007830 nerve conduction Effects 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
Abstract
The invention relates to an insecticidal composition. The effective components of the insecticidal composition are indoxacarb and Paichongding (C17H23ClN4O3), wherein the mass ratio of the indoxacarb to the Paichongding is (40:1)-(1:50). The invention also relates to an application of the insecticidal composition to control of tea lesser leafhoppers. The insecticidal composition has the advantages that after the indoxacarb and the Paichongding are compounded according to the proportion, the obvious synergistic action to pests is achieved, the drug resistance of the pests can be delayed or overcome, the drug amount used in field can be reduced, the environmental pollution and the pesticide residue are effectively reduced, the danger to beneficial organisms is reduced and the single-dose use cost of the indoxacarb can be reduced.
Description
Technical field
The invention belongs to composite pesticide technology, relate to particularly a kind of Pesticidal combination and application thereof with synergistic effect.
Background technology
Indoxacarb (indoxacarb) is a kind of Xin Xing oxadiazine insecticides, and its insecticidal mechanism is by the sodium-ion channel in blocking-up insect nerve cell, makes the nerve cell loss of function of insect and is benumbed, and the coordination ability declines, finally dead.Medicament works by contacting or take food to enter in polypide, does not have cross resistance with other insecticide.Can prevent and treat lepidoptera pest and leafhopper on various crop and ornamental plants, and activity is very high, and each instar larvae is had to good control efficiency.Meanwhile, very safe to natural enemy insect, residual low in crop, be the desirable medicament that can be used for control of insect in Agricultural product without pollution.But, indoxacarb on crop can not in inhale conduction, not ideal enough to the pest controling effect of the hidden harm such as vacuum side of blade, and use cost is high, has therefore limited to a certain extent it and has applied.
The pyridine of piperazine worm is new and effective, wide spectrum, low toxicity nicotinic insecticide, and the mode of action is unique, and the aixs cylinder that acts on insect nerve conduction is touched acceptor, and block nerves conduction, shows as strong feeding deterrent.There is stronger interior suction conduction, can be absorbed rapidly by crop, rice fulgorid is had to good control efficiency.
Summary of the invention
In view of this, provide a kind of synergistic effect remarkable, control efficiency is good, the Pesticidal combination that drug cost is low and application thereof.
A Pesticidal combination, its effective ingredient is indoxacarb and the pyridine of piperazine worm, the mass ratio of described indoxacarb and the pyridine of piperazine worm is 40:1～1:50.
And, the application of above-mentioned Pesticidal combination in control tea lesser leafhopper.
This Pesticidal combination compared with the existing technology, at least can produce following beneficial effect:
1. indoxacarb and the pyridine of piperazine worm are composite according to the above ratio has a notable synergistic effect afterwards to insect;
2. this mechanism of action of killing two kinds of active ingredients in composition is different, and the application of composition can delay or overcome the pesticide resistance of insect;
3. the Pesticidal combination with synergistic effect, can reduce field dosage, effectively reduces environmental pollution and residue of pesticide, reduces the harm to beneficial organism.
4. test shows that this combination can effectively reduce the use cost of indoxacarb single dose.
Embodiment
For making object of the present invention, technical scheme and technological merit clearer, below in conjunction with embodiment, content of the present invention is described further.Specific embodiment only, for explaining the present invention, is not intended to limit the present invention.All any modifications of making within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
The embodiment of the present invention provides a kind of Pesticidal combination, and its effective ingredient is indoxacarb and the pyridine of piperazine worm, and the mass ratio of described indoxacarb and the pyridine of piperazine worm is 40:1～1:50.Preferably, the mass ratio of indoxacarb and the pyridine of piperazine worm is 20:1～1:20.
Inventor, by the result of a large amount of biologicall test experiment sievings, after unexpected discovery indoxacarb and the pyridine of piperazine worm are composite with aforementioned proportion, has significant synergies to tea lesser leafhopper.On the basis of above-mentioned discovery, through composition is carried out to symphyogenetic quantitative analysis, formed the present invention, take indoxacarb as a kind of effective ingredient, take the pyridine of piperazine worm as another active ingredient, two kinds of compositions complement each other, synergy, plays excellent synergistic effect.
The Pesticidal combination of the embodiment of the present invention can be according to the crop of required control, environmental condition of living in, prevent and treat the various factorss such as method, cost accounting, active ingredient is processed into together with carrier (filler) to acceptable any one formulation in pesticides application with auxiliary agent, preferred dosage form is suspending agent, missible oil, aqueous emulsion, wetting powder or water dispersible granules.Adjuvant used, carrier and process technology adopt known component.In above-mentioned various each formulations, the gross mass percentage composition of indoxacarb and the pyridine of piperazine worm is 5%～80%, and for example, when the quality percentage composition of indoxacarb and the pyridine of piperazine worm is respectively 4% and 1%, total content is 5%; When the quality percentage composition of indoxacarb and the pyridine of piperazine worm is respectively 40% and 40%, total content is 80%, shown in the following example of value of concrete gross mass percentage composition.
The combination of active principles of different agricultural chemicals is made to agricultural chemicals, is a kind of effectively and efficiently mode of the upper resistant insect of current development novel pesticide and control agricultural.The agricultural chemicals of different cultivars shows three kinds of type of action: summation action, synergistic effect and antagonism after mixing conventionally.But be specially which kind of effect, unpredictable, only have by lot of experiments and could determine.
Inventor, by a large amount of screening tests, finds that indoxacarb and piperazine worm pyridine combination have obvious synergistic function to tea lesser leafhopper, and thus, the embodiment of the present invention also provides the application of above-mentioned Pesticidal combination in control tea lesser leafhopper.The effect of control tea lesser leafhopper is not only the simple addition of two kinds of medicaments, specifically with following biologicall test example, is illustrated.
Biologicall test example: the composite joint toxicity measuring to tea lesser leafhopper of indoxacarb and the pyridine of piperazine worm
For trying object: tea lesser leafhopper (Empoasca flavescens).Pick up from Nanjing County, Zhangzhou, Fujian city, on tea tree, cultivate, picking consistent 3 age nymph for test.
Test medicine: the former medicine of 95% indoxacarb, the former medicine of 95% piperazine worm pyridine.
Test method: with reference to (banker is auspicious etc., 2009, the drug-fast regional disparity of Fujian Province's tea lesser leafhopper and farm-chemical indoor determination test rule insecticidal n Y/T 1154.11-2008), adopt the tip method of soaking.
Mode of application is judged co-toxicity coefficient (CTC) method that adopts.The computing formula of co-toxicity coefficient is as follows:
Actual measurement toxicity index (ATI)=(standard medicament LC
50/ reagent agent LC
50) * 100
The percentage composition of B in percentage composition+B medicament ATI * mixture of A in theoretical toxicity index (TTI)=A medicament ATI * mixture
Co-toxicity coefficient (CTC)=[the theoretical toxicity index (TTI) of mixture actual measurement toxicity index (ATI)/mixture] * 100
When CTC≤80, composition performance is for antagonism, and as 80 < CTC < 120, composition performance is for summation action, and when CTC >=120, composition performance is synergistic effect.
Result of the test: the composite joint toxicity measuring to tea lesser leafhopper of indoxacarb and the pyridine of piperazine worm the results are shown in Table 1.
Table 1 indoxacarb and piperazine worm pyridine different proportion are composite to tea lesser leafhopper joint toxicity measuring
| Process | LC 50（μg/mL） | ATI | TTI | Co-toxicity coefficient CTC |
| Indoxacarb | 4.76 | 100.0 | ? | ? |
| The pyridine of piperazine worm | 12.57 | 37.9 | ? | ? |
| Indoxacarb 40: piperazine worm pyridine 1 | 3.96 | 120.2 | 98.5 | 122.1 |
| Indoxacarb 20: piperazine worm pyridine 1 | 2.41 | 197.5 | 97.0 | 203.5 |
| Indoxacarb 10: piperazine worm pyridine 1 | 2.56 | 185.9 | 94.4 | 197.1 |
| Indoxacarb 5: piperazine worm pyridine 1 | 2.87 | 165.9 | 89.6 | 185.0 |
| Indoxacarb 1: piperazine worm pyridine 1 | 3.81 | 124.9 | 68.9 | 181.2 |
| Indoxacarb 1: piperazine worm pyridine 5 | 5.36 | 88.8 | 48.2 | 184.2 |
| Indoxacarb 1: piperazine worm pyridine 10 | 6.01 | 79.2 | 43.5 | 182.0 |
| Indoxacarb 1: piperazine worm pyridine 20 | 6.43 | 74.0 | 40.8 | 181.3 |
| Indoxacarb 1: piperazine worm pyridine 50 | 7.58 | 62.8 | 39.4 | 159.5 |
The result of table 1 co-toxicity test shows, indoxacarb and the pyridine of piperazine worm composite in the ratio range of 40:1～1:50 the co-toxicity coefficient CTC to tea lesser leafhopper joint toxicity measuring be all greater than 120, there is synergistic effect.Especially in the ratio range of 20:1～1:20, CTC is all greater than 180, and synergistic effect is remarkable.
In order to make object of the present invention, technical scheme and advantage clearer, the present invention further describes by following specific experiment example, but the present invention is not limited only to these examples.If no special instructions, the ratio of below mentioning (comprising percentage) is all mass ratio.
Embodiment 1:21% indoxacarb piperazine worm pyridine suspending agent (indoxacarb: piperazine worm pyridine=20:1)
Indoxacarb 20%
Piperazine worm pyridine 1%
Alkylaryl polyoxyethylene polyoxypropylene ether 2%
Poly-naphthaldehyde sodium sulfonate 3%
Ethylene glycol 4%
Xanthans 0.8%
Water complements to 100%
Active component, dispersant, wetting agent and water are mixed in the ratio of formula, after grinding and high speed shear, obtain 21% indoxacarb piperazine worm pyridine suspending agent.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 21% indoxacarb piperazine worm pyridine suspending agent are prevented and treated for tea tree tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 78.52%, 71.57% and 82.45%, after dispenser 7 days, the preventive effect of each medicament is respectively 86.93%, 77.42% and 98.27%, after dispenser 15 days, preventive effect is respectively 71.23%, 63.24% and 85.76%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 2 the present embodiment to tea tree tea lesser leafhopper
| Medicament | Using dosage (mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 21% indoxacarb piperazine worm pyridine suspending agent | 10 | 82.45 | 98.27 | 85.76 |
| 15% indoxacarb missible oil | 15 | 78.52 | 86.93 | 71.23 |
| 10% piperazine worm pyridine suspending agent | 30 | 71.57 | 77.42 | 63.24 |
Embodiment 2:20% indoxacarb piperazine worm pyridine missible oil (indoxacarb: piperazine worm pyridine=1:1)
Indoxacarb 10%
Piperazine worm pyridine 10%
Calcium dodecyl benzene sulfonate 3%
OPEO 4%
Methyl-sulfoxide 10%
Turpentine oil complements to 100%
Former medicine, emulsifier and cosolvent etc. by containing active component, add mixing kettle successively by formula rate, stirs, and obtains 20% indoxacarb piperazine worm pyridine missible oil.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 20% indoxacarb piperazine worm pyridine missible oil are prevented and treated for tea tree tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 73.58%, 68.12% and 89.99%, after dispenser 7 days, the preventive effect of each medicament is respectively 85.68%, 75.67% and 97.88%, after dispenser 15 days, preventive effect is respectively 73.52%, 65.41% and 87.36%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 3 the present embodiment to tea lesser leafhopper
| Medicament | Using dosage (mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 20% indoxacarb piperazine worm pyridine missible oil | 10 | 89.99 | 97.88 | 87.36 |
| 15% indoxacarb missible oil | 15 | 73.58 | 85.68 | 73.52 |
| 10% piperazine worm pyridine suspending agent | 30 | 68.12 | 75.67 | 65.41 |
Embodiment 3:30% indoxacarb paichongding water dispersible granule (indoxacarb: piperazine worm pyridine=1:5)
Indoxacarb 5%
Piperazine worm pyridine 25%
Sodium lignin sulfonate 3%
PO-EO block polyether 1%
Sodium alkyl benzene sulfonate 2%
Urea 5%
Attapulgite to 100%
Active ingredient, dispersant, wetting agent, disintegrant and filler are mixed in the ratio of formula, through air-flow crushing, become wetting powder, then add a certain amount of water mixing extruding to make material.After drying screening, obtain 30% indoxacarb paichongding water dispersible granule.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 30% indoxacarb paichongding water dispersible granule are prevented and treated for tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 78.66%, 72.51% and 88.86%, after dispenser 7 days, the preventive effect of each medicament is respectively 82.61%, 78.55% and 92.16%, after dispenser 15 days, preventive effect is respectively 78.34%, 64.19% and 87.65%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 4 the present embodiment to Wild cabbage tea smaller green leaf hopper
| Medicament | Using dosage (g or mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 30% indoxacarb paichongding water dispersible granule | 10 | 88.86 | 92.16 | 87.65 |
| 15% indoxacarb missible oil | 15 | 78.66 | 82.61 | 78.34 |
| 10% piperazine worm pyridine suspending agent | 30 | 72.51 | 78.55 | 64.19 |
Embodiment 4:42% indoxacarb piperazine worm pyridine wetting powder (indoxacarb: piperazine worm pyridine=1:20)
Indoxacarb 2%
Piperazine worm pyridine 40%
Lauryl sodium sulfate 2%
Sodium lignin sulfonate 5%
White carbon 10%
Kaolin complements to 100%
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of formula, after ultra-fine pulverizer disintegrating, obtain 42% indoxacarb piperazine worm pyridine wetting powder.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 42% indoxacarb piperazine worm pyridine wetting powder are prevented and treated for tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 75.66%, 64.31% and 82.47%, after dispenser 7 days, the preventive effect of each medicament is respectively 82.54%, 79.25% and 96.57%, after dispenser 15 days, preventive effect is respectively 76.89%, 65.86% and 88.33%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 5 the present embodiment to tea lesser leafhopper
| Medicament | Using dosage (g or mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 42% indoxacarb piperazine worm pyridine wetting powder | 10 | 82.47 | 96.57 | 88.33 |
| 15% indoxacarb missible oil | 15 | 75.66 | 82.54 | 76.89 |
| 10% piperazine worm pyridine suspending agent | 30 | 64.31 | 79.25 | 65.86 |
Embodiment 5:20% indoxacarb piperazine worm pyridine suspending agent (indoxacarb: piperazine worm pyridine=1:1)
Indoxacarb 10%
Piperazine worm pyridine 10%
Alkylaryl polyoxyethylene polyoxypropylene ether 2%
Poly-naphthaldehyde sodium sulfonate 3%
Ethylene glycol 4%
Xanthans 0.8%
Water complements to 100%
Active component, dispersant, wetting agent and water are mixed in the ratio of formula, after grinding and high speed shear, obtain 20% indoxacarb piperazine worm pyridine suspending agent.
15% indoxacarb suspending agent, 10% piperazine worm pyridine suspending agent, 20% indoxacarb piperazine worm pyridine suspending agent are prevented and treated for tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 69.75%, 62.32% and 87.41%, after dispenser 7 days, the preventive effect of each medicament is respectively 80.22%, 77.84% and 96.48%, after dispenser 15 days, preventive effect is respectively 74.36%, 66.21% and 85.92%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 6 the present embodiment to tea lesser leafhopper
| Medicament | Using dosage (mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 20% indoxacarb piperazine worm pyridine suspending agent | 10 | 87.41 | 96.48 | 85.92 |
| 15% indoxacarb suspending agent | 15 | 69.75 | 80.22 | 74.36 |
| 10% piperazine worm pyridine suspending agent | 30 | 62.32 | 77.84 | 66.21 |
Embodiment 6:20% indoxacarb piperazine worm pyridine aqueous emulsion (indoxacarb: piperazine worm pyridine=1:1)
Indoxacarb 10%
Piperazine worm pyridine 10%
Calcium dodecyl benzene sulfonate 5%
Phenol formaldehyde resin APEO 2%
150# solvent naphtha 15%
Methyl-sulfoxide 12%
Ethylene glycol 5%
Xanthans 1%
Deionized water is mended to 100%
Antifreezing agent, water, thickener are fully stirred into water, by former medicine, solvent, emulsifier etc. in proportion fully mix and blend dissolve and make oil phase, under constantly stirring, water is directly added in oil phase, stir and make 20% indoxacarb piperazine worm pyridine aqueous emulsion.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 20% indoxacarb piperazine worm pyridine aqueous emulsion are prevented and treated for tea tree tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 78.52%, 71.41% and 87.52%, after dispenser 7 days, the preventive effect of each medicament is respectively 82.31%, 78.42% and 94.56%, after dispenser 15 days, preventive effect is respectively 71.63%, 65.36% and 88.41%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 7 the present embodiment to tea lesser leafhopper
| Medicament | Using dosage (mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 20% indoxacarb piperazine worm pyridine aqueous emulsion | 10 | 87.52 | 94.56 | 88.41 |
| 15% indoxacarb missible oil | 15 | 78.52 | 82.31 | 71.63 |
| 10% piperazine worm pyridine suspending agent | 30 | 71.41 | 78.42 | 65.36 |
Embodiment 7:41% indoxacarb piperazine worm pyridine suspending agent (indoxacarb: piperazine worm pyridine=40:1)
Indoxacarb 40%
Piperazine worm pyridine 1%
Alkylaryl polyoxyethylene polyoxypropylene ether 2%
Poly-naphthaldehyde sodium sulfonate 3%
Ethylene glycol 4%
Xanthans 0.8%
Water complements to 100%
Active component, dispersant, wetting agent and water are mixed in the ratio of formula, after grinding and high speed shear, obtain 41% indoxacarb piperazine worm pyridine suspending agent.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 41% indoxacarb piperazine worm pyridine suspending agent are prevented and treated for tea tree tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 72.58%, 68.74% and 86.93%, after dispenser 7 days, the preventive effect of each medicament is respectively 87.15%, 79.42% and 96.85%, after dispenser 15 days, preventive effect is respectively 73.46%, 67.85% and 86.23%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 8 the present embodiment to tea tree tea lesser leafhopper
| Medicament | Using dosage (mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 41% indoxacarb piperazine worm pyridine suspending agent | 10 | 86.93 | 96.85 | 86.23 |
| 15% indoxacarb missible oil | 15 | 72.58 | 87.15 | 73.46 |
| 10% piperazine worm pyridine suspending agent | 30 | 68.74 | 79.42 | 67.85 |
Embodiment 8:25.5% indoxacarb piperazine worm pyridine suspending agent (indoxacarb: piperazine worm pyridine=0.5:25)
Indoxacarb 0.5%
Piperazine worm pyridine 25%
Alkylaryl polyoxyethylene polyoxypropylene ether 2%
Poly-naphthaldehyde sodium sulfonate 3%
Ethylene glycol 4%
Xanthans 0.8%
Water complements to 100%
Active component, dispersant, wetting agent and water are mixed in the ratio of formula, after grinding and high speed shear, obtain 25.5% indoxacarb piperazine worm pyridine suspending agent.
15% indoxacarb missible oil, 10% piperazine worm pyridine suspending agent, 25.5% indoxacarb piperazine worm pyridine suspending agent are prevented and treated for tea tree tea lesser leafhopper.After dispenser, the control efficiency of 1 day is respectively 78.47%, 70.25% and 81.46%, after dispenser 7 days, the preventive effect of each medicament is respectively 82.31%, 76.58% and 94.78%, after dispenser 15 days, preventive effect is respectively 71.66%, 65.41% and 84.22%, the composite rear synergistic effect of indoxacarb and the pyridine of piperazine worm is obvious, to the control efficiency of tea lesser leafhopper, quick-acting and lasting effect all significantly better than single dose.
The field control effect of table 9 the present embodiment to tea tree tea lesser leafhopper
| Medicament | Using dosage (mL/667m 2） | 1d preventive effect % | 7d preventive effect % | 15d preventive effect % |
| 25.5% indoxacarb piperazine worm pyridine suspending agent | 10 | 81.46 | 94.78 | 84.22 |
| 15% indoxacarb missible oil | 15 | 78.47 | 82.31 | 71.66 |
| 10% piperazine worm pyridine suspending agent | 30 | 70.25 | 76.58 | 65.41 |
From indoxacarb and the composite field efficacy to tea tree tea lesser leafhopper of piperazine worm pyridine, composite have a synergistic effect, and single dose control efficiency obviously improves relatively, can reduce the field rotating medicine number of times of dosage simultaneously, delays pest resistance to insecticide and produce.Lasting period extends, and can reduce medication number of times, reduces cost accounting.
These are only preferred embodiment of the present invention, not in order to limit the present invention, all any modifications of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.
Claims (5)
1. a Pesticidal combination, is characterized in that: the effective ingredient of described Pesticidal combination is indoxacarb and the pyridine of piperazine worm, and the mass ratio of described indoxacarb and the pyridine of piperazine worm is 40:1～1:50.
2. Pesticidal combination according to claim 1, is characterized in that, the mass ratio of described indoxacarb and the pyridine of piperazine worm is 20:1～1:20.
3. Pesticidal combination according to claim 1 and 2, is characterized in that, the formulation of described Pesticidal combination is missible oil, aqueous emulsion, suspending agent, wetting powder or water dispersible granules.
4. Pesticidal combination according to claim 3, is characterized in that, described indoxacarb and the gross mass percentage composition of piperazine worm pyridine in each formulation are 5%～80%.
5. the application in control tea lesser leafhopper according to the Pesticidal combination described in claim 1 to 4 any one.
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| CN101779663B (en) * | 2010-01-25 | 2012-07-04 | 陕西上格之路生物科学有限公司 | Disinfestation composition containing paichongding (IPP) and chlorpyrifos |
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| CN101045728A (en) * | 2006-03-28 | 2007-10-03 | 华东理工大学 | Preparation method and use of compound with high insecticidal activity |
| EP1922929A1 (en) * | 2006-08-31 | 2008-05-21 | Syngeta Participations AG | A method of protecting a plant propagation material, a plant, part of a plant and/or plant organ |
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| Medicinal Chemistry Letters》.2008,第18卷第6513-6516页. * |
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| Xusheng Shao 等.cis-Nitromethylene neonicotinoids as new nicotinic family: Synthesis,structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-a]pyridine.《Bioorganic & * |
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