CN101700034B - Pesticide composition - Google Patents
Pesticide composition Download PDFInfo
- Publication number
- CN101700034B CN101700034B CN 200910164496 CN200910164496A CN101700034B CN 101700034 B CN101700034 B CN 101700034B CN 200910164496 CN200910164496 CN 200910164496 CN 200910164496 A CN200910164496 A CN 200910164496A CN 101700034 B CN101700034 B CN 101700034B
- Authority
- CN
- China
- Prior art keywords
- buprofezin
- mti
- behind
- composition
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 40
- 239000000575 pesticide Substances 0.000 title abstract description 6
- 239000005885 Buprofezin Substances 0.000 claims abstract description 104
- PRLVTUNWOQKEAI-VKAVYKQESA-N buprofezin Chemical compound O=C1N(C(C)C)\C(=N\C(C)(C)C)SCN1C1=CC=CC=C1 PRLVTUNWOQKEAI-VKAVYKQESA-N 0.000 claims abstract description 93
- 229920000742 Cotton Polymers 0.000 claims abstract description 13
- 241000258937 Hemiptera Species 0.000 claims abstract description 13
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 12
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 11
- 235000009566 rice Nutrition 0.000 claims abstract description 11
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 6
- 235000013311 vegetables Nutrition 0.000 claims abstract description 6
- 240000007594 Oryza sativa Species 0.000 claims abstract 2
- 239000000843 powder Substances 0.000 claims description 14
- 239000000375 suspending agent Substances 0.000 claims description 14
- 238000009736 wetting Methods 0.000 claims description 14
- 239000000839 emulsion Substances 0.000 claims description 11
- 230000000361 pesticidal effect Effects 0.000 claims description 11
- 239000004562 water dispersible granule Substances 0.000 claims description 11
- 239000004480 active ingredient Substances 0.000 claims description 9
- 238000009472 formulation Methods 0.000 claims description 4
- 239000004530 micro-emulsion Substances 0.000 claims description 3
- -1 leyrodid Species 0.000 abstract description 19
- YKBZOVFACRVRJN-UHFFFAOYSA-N dinotefuran Chemical compound [O-][N+](=O)\N=C(/NC)NCC1CCOC1 YKBZOVFACRVRJN-UHFFFAOYSA-N 0.000 abstract description 7
- 230000009471 action Effects 0.000 abstract description 6
- 241001414720 Cicadellidae Species 0.000 abstract description 3
- 239000004615 ingredient Substances 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 241001466042 Fulgoromorpha Species 0.000 abstract 1
- 238000003912 environmental pollution Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 42
- 230000003449 preventive effect Effects 0.000 description 28
- 230000002195 synergetic effect Effects 0.000 description 18
- 239000002270 dispersing agent Substances 0.000 description 17
- 239000003995 emulsifying agent Substances 0.000 description 17
- 238000000034 method Methods 0.000 description 17
- 239000003921 oil Substances 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 12
- 239000002904 solvent Substances 0.000 description 11
- 239000000080 wetting agent Substances 0.000 description 10
- 241000209094 Oryza Species 0.000 description 9
- 238000005507 spraying Methods 0.000 description 9
- 231100000419 toxicity Toxicity 0.000 description 9
- 230000001988 toxicity Effects 0.000 description 9
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 8
- 239000003381 stabilizer Substances 0.000 description 8
- 241000254127 Bemisia tabaci Species 0.000 description 7
- 239000000306 component Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 6
- YSUQLAYJZDEMOT-UHFFFAOYSA-N 2-(butoxymethyl)oxirane Chemical compound CCCCOCC1CO1 YSUQLAYJZDEMOT-UHFFFAOYSA-N 0.000 description 5
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 5
- 239000000945 filler Substances 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 4
- 241000675108 Citrus tangerina Species 0.000 description 4
- 241001498622 Cixius wagneri Species 0.000 description 4
- 241001556089 Nilaparvata lugens Species 0.000 description 4
- 241000819999 Nymphes Species 0.000 description 4
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 4
- 241000176086 Sogatella furcifera Species 0.000 description 4
- 239000003905 agrochemical Substances 0.000 description 4
- 239000011230 binding agent Substances 0.000 description 4
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 206010059866 Drug resistance Diseases 0.000 description 3
- 241000238631 Hexapoda Species 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 239000006184 cosolvent Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000002917 insecticide Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000010452 phosphate Substances 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 2
- 241001600407 Aphis <genus> Species 0.000 description 2
- 241001182720 Cacopsylla pyrisuga Species 0.000 description 2
- 235000009024 Ceanothus sanguineus Nutrition 0.000 description 2
- 241001465977 Coccoidea Species 0.000 description 2
- 241000086608 Empoasca vitis Species 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 2
- 240000003553 Leptospermum scoparium Species 0.000 description 2
- 235000015459 Lycium barbarum Nutrition 0.000 description 2
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 240000003768 Solanum lycopersicum Species 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 235000012211 aluminium silicate Nutrition 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- 235000021329 brown rice Nutrition 0.000 description 2
- 239000007957 coemulsifier Substances 0.000 description 2
- 239000007859 condensation product Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 230000000749 insecticidal effect Effects 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 229950011293 parathiazine Drugs 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920005646 polycarboxylate Polymers 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 229920000151 polyglycol Polymers 0.000 description 2
- 239000010695 polyglycol Substances 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000001294 propane Substances 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- WCXDHFDTOYPNIE-RIYZIHGNSA-N (E)-acetamiprid Chemical compound N#C/N=C(\C)N(C)CC1=CC=C(Cl)N=C1 WCXDHFDTOYPNIE-RIYZIHGNSA-N 0.000 description 1
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 1
- 239000005875 Acetamiprid Substances 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000005906 Imidacloprid Substances 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 229920001732 Lignosulfonate Polymers 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 description 1
- 239000005925 Pymetrozine Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000002528 anti-freeze Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- DIRFUJHNVNOBMY-UHFFFAOYSA-N fenobucarb Chemical compound CCC(C)C1=CC=CC=C1OC(=O)NC DIRFUJHNVNOBMY-UHFFFAOYSA-N 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003165 hydrotropic effect Effects 0.000 description 1
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 description 1
- 229940056881 imidacloprid Drugs 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- PSZYNBSKGUBXEH-UHFFFAOYSA-M naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-M 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- QHMTXANCGGJZRX-WUXMJOGZSA-N pymetrozine Chemical compound C1C(C)=NNC(=O)N1\N=C\C1=CC=CN=C1 QHMTXANCGGJZRX-WUXMJOGZSA-N 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Abstract
The invention discloses a synergia pesticide composition which takes buprofezin and dinotefuran as effective ingredients and the mass ratio of the buprofezin and dinotefuran is 50:1-1:50. The pesticide composition is suitable for rice, cotton, fruit tree, vegetables for preventing various homoptera insect pests such as plant hoppers, leaf hoppers and aleyrodid; the synergia pesticide composition has the advantages that: the control effect including quick action and sustaining action is high, low dose administration and less environmental pollution.
Description
Technical field
The present invention relates to a kind of Pesticidal combination, be specifically related to the composite Pesticidal combination of a kind of Buprofezin and MTI-446, be used for the insect of control harm plant.
Background technology
Buprofezin (Buprofezin), chemical name is 2-tertiary butyl imino group-3-isopropyl-5-phenyl-1,3,5-thiadiazine-4-ketone, mechanism of action is for suppressing the synthetic and interference metabolism of insect chitin, cause cast off a skin deformity or wing deformity and slowly dead of nymph, the homoptera pest nymphs such as plant hopper, leafhopper are had good preventive and therapeutic effect.The Buprofezin action of contace poison is strong, stomach poison function is also arranged, shortcoming is not obvious to homoptera pest adult control efficiency, in addition, resistance (monitoring for resistance of brown planthopper parathiazine ketone, rice in China science, 2008 that the insect parathiazine ketone such as rice fulgorid has produced low-medium level have been found at present, increased more than one times when 22 (2)), the dosage of field control is than initial the application.
MTI-446 (Dinot efuran), chemical name are (RS) 1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine, are to be developed the earliest by Mitsui chemical company, at the third generation nicotinic insecticide of listing in 2002.This medicament insecticidal spectrum is wide, has remarkable interior sorptivety and thoroughly acts on, and namely shown very high insecticidal activity at very low dosage.This medicament is fool proof to mammal, birds and aquatile, and crop without poisoning, is had efficiently Homoptera, Lepidoptera, Diptera pest on numerous crops such as paddy rice, fruit tree, vegetables.
Mainly contain the Pesticidal combinations such as Buprofezin and chlopyrifos, Acetamiprid, Imidacloprid, pymetrozine, Bassa about the composition patent that is mixed of Buprofezin is existing published.To at present, there is not yet the bibliographical information of relevant Buprofezin and MTI-446 complex preparation.
Summary of the invention
The present invention aims to provide the safe and efficient insecticides that uses on a kind of suitable agricultural, homoptera pest all had outstanding control efficiency from the nymph to the adult.
For solving the problems of the technologies described above, the inventor finds that by lot of experiments Buprofezin and MTI-446 are composite in certain proportion, is having significant synergies aspect the control homoptera pest.
On the basis of above-mentioned discovery, through composition is carried out symphyogenetic quantitative analysis, formed technical scheme of the present invention, namely take Buprofezin and MTI-446 as active ingredient, the mass ratio of Buprofezin and MTI-446 is 50: 1-1: 50, and ratio is 10 preferably: 1-1: 10.
The present composition can be prepared into known method any one formulation that is fit to agricultural use, reasonable formulation is microemulsion, suspending agent, aqueous emulsion, water dispersible granules, missible oil and wetting powder etc., and the total content of active ingredient is 1-80% in the preparation.
The adjuvant that uses in the composition of the present invention comprises that solvent, emulsifier, dispersant, wetting agent, stabilizing agent, antifreezing agent, thickener, pH adjusting agent, bleeding agent etc. and other are of value to the known substance that active ingredient is stablized and drug effect is brought into play in storing and using, all be various compositions commonly used in the pesticidal preparations or that permission is used, be not particularly limited, concrete composition and consumption require to determine by simple experiment according to prescription.
Product described in the invention can the finished product preparation form provide, and namely each material mixes in the composition, and the composition of composition also can provide with the single dose form, directly directly mixes in bucket or tank before the use, then is diluted to required concentration.
Pesticidal combination of the present invention is mainly used in the homoptera pest on paddy rice, cotton, fruit tree, the vegetables.
The invention has the beneficial effects as follows:
1, compare with single dose, the present composition has obvious synergistic effect to homoptera pest, is particularly useful for the multiple homoptera pests such as paddy rice, cotton, fruit tree, vegetables control plant hopper, leafhopper, aleyrodid.
2, compare with single dose, the present composition has quick-acting and lasting effect.
2, present composition prevention and treatment range has covered all worm age grade sections of pest control.
3, the present composition is conducive to the generation that overcomes disease drug resistance and delay disease drug resistance.
4, the alternative high-toxic pesticide of the present composition, and significantly reduce the field dosage, reduce harm and residue of pesticide to environment.
Embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer, the present invention describes with following specific embodiment, but the present invention is limited to absolutely not these examples.
The combination of active principles of different agricultural chemicals being carried out composite, is a kind of effectively and efficiently mode that solves at present some problems in the agricultural chemicals single dose application process.The agricultural chemicals of different cultivars shows three kinds of type of action after mixing usually, and namely summation action, synergistic effect and antagonism act on but which kind of is specially, and be unpredictable, only has by lot of experiments and just can know.Compound synergic is well filled a prescription, and can improve actual control efficiency, reduces the usage amount of agricultural chemicals, also helps the generation of delaying drug resistance, is the important means of integrated control.
The present composition is take Buprofezin as a kind of active ingredient, take MTI-446 as another kind of active ingredient, combination has obvious synergistic function to the homoptera pest on paddy rice, cotton, fruit tree, the vegetables between them, and be not only the simple addition of two kinds of pharmacy effects, specifically be illustrated with following biologicall test example.Biologicall test example 1: cotton Bemisia tabaci indoor virulence test
Experimental pharmacy: 95% MTI-446 (Nanjing chemical industry Co., Ltd of rich nation), 95% Buprofezin (Feng Huagong Co., Ltd is expected in Nanjing) (together lower).
Test method is with reference to " the agricultural industry criteria NY/T1154.14-2008 of the People's Republic of China (PRC) ", adopt leaf dipping method: win the fresh tomato blade and be placed on to dilute and take out, be placed on indoor drying after soaking 10s in the good liquid, then be placed in the culture dish of diameter 9cm, each culture dish is put 1 tomato leaf.Cotton Bemisia tabaci nymph in 2 age is chosen in the culture dish gently, and every ware has 30 of nymphs, is the culture dish sealing with preservative film, pricks several apertures at preservative film and is beneficial to breathe freely.Then put temperature and be 21 ℃, photoperiod and be 16h: 8h (L: raise in incubator D), the clear water contrast, each concentration repeats 3 times.After 48 hours, under binocular microscope, check death condition (touch gently the cotton Bemisia tabaci adults with dissecting needle, the motionless person of health is dead).General each processing arranges 6 concentration gradients.
Calculate virulence equation and lethal concentration of 50 LC with method of least squares
50, according to the toxicity index of the abundant calculating medicament of Sun Yun and the co-toxicity coefficient of using with (CTC value).
Actual measurement toxicity index (ATI)=(standard medicament LC
50/ reagent agent LC
50) * 100
The percentage composition of B in the percentage composition of A+B medicament toxicity index * mixture in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
When CTC≤80, then the composition performance is for antagonism, and when 80<CTC<120, then the composition performance is for summation action, and when CTC 〉=120, then the composition performance is synergistic effect.
The serial proportioning of table 1 composition is to the Toxicity Determination result of cotton Bemisia tabaci
Process | LC 50(mg/kg) | ATI | TTI | Co-toxicity coefficient CTC |
Buprofezin | 0.73 | 100 | / | / |
MTI-446 | 0.29 | 252 | / | / |
Buprofezin 50: MTI-446 1 | 0.27 | 270 | 102.97 | 263 |
Buprofezin 20: MTI-446 1 | 0.25 | 292 | 107.22 | 272 |
Buprofezin 10: MTI-446 1 | 0.17 | 429 | 113.79 | 377 |
Buprofezin 5: MTI-446 1 | 0.13 | 562 | 125.29 | 448 |
Buprofezin 1: MTI-446 1 | 0.09 | 811 | 175.86 | 461 |
Buprofezin 1: MTI-446 5 | 0.08 | 913 | 226.44 | 403 |
Buprofezin 1: MTI-446 10 | 0.1 | 730 | 237.93 | 307 |
Buprofezin 1: MTI-446 20 | 0.14 | 521 | 244.50 | 213 |
Buprofezin 1: MTI-446 50 | 0.22 | 332 | 248.75 | 133 |
Result of the test shows, MTI-446 and buprofezin compound control cotton Bemisia tabaci, proportioning are between 50: 1~1: 50 the time, co-toxicity coefficient has synergistic effect more than 130, and proportioning is between 10: 1~1: 10 the time, co-toxicity coefficient all is higher than 300, and synergistic effect is more obvious.
Biologicall test example 2: rice fulgorid (brown planthopper) indoor virulence test
Test method is with reference to " the agricultural industry criteria NY/T1154.11-2008 of the People's Republic of China (PRC) " and " the agricultural industry criteria NY/T1154.7-2006 of the People's Republic of China (PRC) ".Adopt rice stem infusion process: extract with root the rice strain at healthy and strong tillering stage to booting initial stage, clean, be cut into the long band root rice stem of 15cm, one group of 3 strain, dry in the air to the surface without washmarking in the place in the cool place.The rice stem was soaked 30 seconds in the good medicament of dilution respectively, after taking-up is dried, encase root with the absorbent cotton that soaks and put into and cultivate cup, draw 3 mid-term in age nymph put into and cultivate cup, 20 every glass, putting temperature and be 27 ℃, photoperiod is 16h: 8h (L: raise in incubator D).The clear water contrast, each concentration repeats 3 times.Check death toll after 4 days.
The serial proportioning of table 2 composition is to the Toxicity Determination result of rice fulgorid
Process | LC50(mg/kg) | ATI | TTI | Co-toxicity coefficient CTC |
Buprofezin | 0.62 | 100 | / | / |
MTI-446 | 0.37 | 168 | / | / |
Buprofezin 50: MTI-446 1 | 0.36 | 172 | 101.32 | 170 |
Buprofezin 20: MTI-446 1 | 0.34 | 182 | 103.22 | 177 |
Buprofezin 10: MTI-446 1 | 0.25 | 248 | 106.14 | 234 |
Buprofezin 5: MTI-446 1 | 0.19 | 326 | 111.26 | 293 |
Buprofezin 1: MTI-446 1 | 0.13 | 477 | 133.78 | 356 |
Buprofezin 1: MTI-446 5 | 0.11 | 564 | 156.31 | 361 |
Buprofezin 1: MTI-446 10 | 0.14 | 443 | 161.43 | 274 |
Buprofezin 1: MTI-446 20 | 0.21 | 295 | 164.35 | 180 |
Buprofezin 1: MTI-446 50 | 0.29 | 214 | 166.24 | 129 |
Result of the test shows, MTI-446 and buprofezin compound control rice fulgorid, and proportioning is between 50: 1~1: 50 the time, co-toxicity coefficient is more than 120, the synergistic effect that has, and proportioning is between 10: 1~1: 10 the time, listed proportioning co-toxicity coefficient all is higher than 230, and synergistic effect is more obvious.
Pesticidal combination of the present invention can be prepared into known method the formulations such as microemulsion, suspending agent, aqueous emulsion, water dispersible granules, missible oil and wetting powder that are fit to agricultural use.Below describe with specific embodiment, percentage is mass percent in the prescription.Active component refers to Buprofezin and MTI-446 in the present specification.
Below in conjunction with embodiment further instruction of the present invention, but the present invention is not limited thereto.
Embodiment 1:70% Buprofezin MTI-446 water dispersible granules (50: 1)
Buprofezin (95%) 72.2g
MTI-446 (95%) 1.4g
Negel formaldehyde condensation products (dispersant) 4g
Polycarboxylate (dispersant) 3g
Lauryl sodium sulfate (wetting agent) 1g
Polyethylene glycol (binding agent) 3g
White carbon (carrier) 10.4g
Kaolin (filler) 5g
Active component, dispersant, wetting agent, binding agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder through air-flow crushing, add again a certain amount of water mixing extruding and make material.Obtain 70% Buprofezin MTI-446 water dispersible granules after the drying screening.
This embodiment is applied to prevent and treat the oranges and tangerines aleyrodid.With 3500 times of 70% Buprofezin MTI-446 water dispersible granules thin ups (Buprofezin valid density is 196 μ g/ml, the valid density 4 μ g/ml of MTI-446) sprayings, the control efficiency of 3 days and 7 days is respectively 89.9%, 96.8% behind the medicine.Contrast medicament 25% Buprofezin wetting powder (commercially available) by 1000 times (valid density is 250 μ g/ml) and 25% MTI-446 water dispersible granules by 2500 times (valid density is 100 μ g/ml), use with same method, 3 days preventive effect is respectively 82.1% and 65.7% behind the medicine, and 7 days preventive effect is 84.4% and 82.4% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and significantly better than single dose, 3 days show behind the medicine, and quick-acting obviously to be better than Buprofezin alone to the preventive effect of oranges and tangerines aleyrodid.
Embodiment 2:20% Buprofezin MTI-446 suspending agent (20: 1)
Buprofezin (95%) 20.1g
MTI-446 (95%) 1.01g
Butyl glycidyl ether (stabilizing agent) 5g
Lauryl sodium sulfate (wetting agent) 7g
Xanthans (thickener) 0.2g
Ethylene glycol (antifreezing agent) 5g
Sorbitan monooleate (wetting agent) 3g
Alkyl polyglycol ether phosphate (dispersant) 1.5g
Expoxy propane/epoxyethane block copolymer (dispersant) 1.5g
Deionized water 45.8g
The former medicine of active ingredient, dispersant and other auxiliary agent and water are mixed in the ratio of filling a prescription, after grinding and/or high speed shear, obtain 20% Buprofezin MTI-446 suspending agent.
This exemplary application is in control cane suger mealybug.With 1000 times of 20% Buprofezin MTI-446 suspending agents (MTI-446 valid density is 190.5 μ g/ml, the valid density 9.5 μ g/ml of Buprofezin) thin up spraying, the control efficiency of 3 days and 7 days is respectively 92.3%, 94.1% behind the medicine.25% Buprofezin wetting powder by 1000 times (valid density is 250 μ g/ml) and 25% MTI-446 wetting powder by 1000 times (valid density is 250 μ g/ml), use with same method, 3 days preventive effect is respectively 78.6% and 82.3% behind the medicine, and 7 days preventive effect is 80.1% and 84.6% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect cane suger mealybug is significantly better than single dose.
Embodiment 3:1% Buprofezin dinotefuran micron-emulsion (10: 1)
Buprofezin (95%) 0.96g
MTI-446 (95%) 0.09g
Butyl glycidyl ether (stabilizing agent) 2g
DMF (solvent) 2g
Isobutanol (cosolvent) 2g
Dimethylbenzene (solvent) 3g
Alkylphenol polyoxyethylene (emulsifier) 2g
Phenethyl phenol polyethenoxy ether (emulsifier) 4g
Calcium dodecyl benzene sulfonate (emulsifier) 2g
Deionized water 81.95g
The former medicine of effective ingredient, organic solvent, stabilizing agent, emulsifier are added together, form even oil phase, hydrotropic solvent mixes the even water of formation with water, and oil phase is mixed with water, and high-speed stirred forms 1% Buprofezin dinotefuran micron-emulsion.
This exemplary application is in control wheat small brown rice planthopper.With 100 times of 1% Buprofezin dinotefuran micron-emulsions (Buprofezin valid density is 91 μ g/ml, the valid density 9 μ g/ml of MTI-446) thin up spraying, the control efficiency of 3 days and 7 days is respectively 88.9%, 90.3% behind the medicine.25% Buprofezin wetting powder by 1000 times (valid density is 250 μ g/ml) and 10% dinotefuran micron-emulsion by 1000 times (valid density is 100 μ g/ml), use with same method, 3 days preventive effect is respectively 74.13% and 76.3% behind the medicine, and 7 days preventive effect is 83.7% and 80.2% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect wheat small brown rice planthopper is significantly better than single dose.
Embodiment 4:15% Buprofezin MTI-446 aqueous emulsion (3: 1)
Buprofezin (95%) 11.8g
MTI-446 (95%) 3.9g
Butyl glycidyl ether (stabilizing agent) 5g
DMF (solvent) 3g
Dimethylbenzene (solvent) 5g
Polyvinyl alcohol (dispersant) 1.5g
Isobutanol (co-emulsifier) 3g
Fatty alcohol glyceride-polysorbate ester admixture (emulsifier) 2.5g
Ethoxylated alkyl phosphate ester (emulsifier) 2g
Calcium dodecyl benzene sulfonate (emulsifier) 2g
Deionized water 60.3g
The former medicine of effective ingredient, stabilizing agent, solvent, emulsifier, co-emulsifier are added together, mix the formation oil phase, polyvinyl alcohol is water-soluble, under agitation mix with oil phase, even through high-speed stirred again, form 15% Buprofezin MTI-446 aqueous emulsion.
This exemplary application is in the control Brown Planthopper.With 1000 times of 15% Buprofezin MTI-446 aqueous emulsions (Buprofezin valid density is 112.5 μ g/ml, the valid density 37.5 μ g/ml of MTI-446) thin up spraying, the control efficiency of 3 days and 7 days is respectively 91.2%, 93.7% behind the medicine.25% Buprofezin wetting powder by 1000 times (valid density is 250 μ g/ml) and 10% MTI-446 aqueous emulsion by 1000 times (valid density is 100 μ g/ml), use with same method, 3 days preventive effect is respectively 71.1% and 82.3% behind the medicine, and 7 days preventive effect is 83.3% and 75.7% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect Brown Planthopper is significantly better than single dose.
Embodiment 5:10% Buprofezin MTI-446 missible oil (1: 1)
Buprofezin (95%) 5.3g
MTI-446 (95%) 5.3g
Butyl glycidyl ether (stabilizing agent) 2g
DMF (cosolvent) 4g
Alkylphenol polyoxyethylene (emulsifier) 2g
Phenethyl phenol polyethenoxy ether (emulsifier) 4g
Calcium dodecyl benzene sulfonate (emulsifier) 4g
Dimethylbenzene (solvent) 69.4g
The former medicine of active component, emulsifier and the cosolvent ratio in prescription is added in the mixing kettle successively, stir, make 10% Buprofezin MTI-446 missible oil.
This exemplary application is in control oranges and tangerines scale insect.With 500 times of 10% Buprofezin MTI-446 missible oil (Buprofezin valid density is 100 μ g/ml, the valid density 100 μ g/ml of MTI-446) thin up spraying, the control efficiency of 3 days and 7 days is respectively 85.9%, 93.3% behind the medicine.20% Buprofezin missible oil by 1000 times (valid density is 200 μ g/ml) and 5% MTI-446 missible oil by 250 times (valid density is 200 μ g/ml), use with same method, 3 days preventive effect is respectively 48.3% and 79.1% behind the medicine, and 7 days preventive effect is 81.6% and 62.4% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect oranges and tangerines scale insect is significantly better than single dose.
Embodiment 6:20% Buprofezin MTI-446 wetting powder (1: 3)
Buprofezin (95%) 5.2g
MTI-446 (95%) 15.6g
Lauryl sodium sulfate (wetting agent) 2g
Lignosulfonates (dispersant) 4g
Naphthalene sulfonate (dispersant) 3g
Kaolin (filler) 60.2g
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, behind ultra-fine pulverizer disintegrating, namely get 20% MTI-446 Buprofezin wetting powder.
This exemplary application is in the control wooly aphis.With 2000 times of 20% Buprofezin MTI-446 wetting powders (Buprofezin valid density is 25 μ g/ml, the valid density 75 μ g/ml of MTI-446) thin up spraying, the control efficiency of 3 days and 7 days is respectively 81.2%, 88.9% behind the medicine.25% Buprofezin wetting powder by 1000 times (valid density is 250 μ g/ml) and 25% MTI-446 suspending agent by 2500 times (valid density is 100 μ g/ml), use with same method, 3 days preventive effect is respectively 33.8% and 72.5% behind the medicine, and 7 days preventive effect is 51.3% and 70.3% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect wooly aphis is significantly better than single dose.
Embodiment 7:40% Buprofezin MTI-446 missible oil (1: 10)
Buprofezin (95%) 3.8g
MTI-446 (95%) 38g
Butyl glycidyl ether (stabilizing agent) 4g
DMF (solvent) 5g
Alkylphenol polyoxyethylene (emulsifier) 5g
Phenethyl phenol polyethenoxy ether (emulsifier) 6g
Calcium dodecyl benzene sulfonate (emulsifier) 4g
Dimethylbenzene (solvent) 34.2g
The ratio in prescription such as the former medicine of active component, emulsifier and solvent is added in the mixing kettle successively, stir, make 40% Buprofezin MTI-446 missible oil.
This exemplary application is in control cotton Bemisia tabaci.With 4000 times of 40% Buprofezin MTI-446 missible oil (Buprofezin valid density is 9 μ g/ml, the valid density 91 μ g/ml of MTI-446) thin up spraying, the control efficiency of 3 days and 7 days is respectively 82.3%, 89.7% behind the medicine.25% buprofezin suspension agent (commercially available) by 1000 times (valid density is 250 μ g/ml) and 5% MTI-446 missible oil by 500 times (valid density is 100 μ g/ml), use with same method, 3 days preventive effect is respectively 46.1% and 70.4% behind the medicine, and 7 days preventive effect is 73.2% and 80.4% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect cotton Bemisia tabaci is significantly better than single dose.
Embodiment 8:30% Buprofezin MTI-446 suspending agent (1: 20)
Buprofezin (95%) 1.5g
MTI-446 (95%) 30.1g
Lauryl sodium sulfate (wetting agent) 5g
Xanthans (thickener) 0.2g
Ethylene glycol (antifreeze) 2g
Phenethyl phenol polyethenoxy ether (dispersant) 3g
Alkyl polyglycol ether phosphate (dispersant) 3.5g
Expoxy propane/epoxyethane block copolymer (dispersant) 1.5g
Deionized water 53.2g
The ratio of each component such as the former medicine of active ingredient, dispersant, wetting agent and water in prescription mixed, after grinding and/or high speed shear, obtain 30% Buprofezin MTI-446 suspending agent.
This exemplary application is in the control pear sucker.With 2000 times of 30% Buprofezin MTI-446 suspending agents (Buprofezin valid density is 7 μ g/ml, the valid density 143 μ g/ml of MTI-446) thin up spraying, the control efficiency of 3 days and 7 days is respectively 82.2%, 86.9% behind the medicine.25% buprofezin suspension agent by 1000 times (valid density is 250 μ g/ml) and 25% MTI-446 suspending agent by 1000 times (valid density is 250 μ g/ml), use with same method, 3 days preventive effect is respectively 37.8% and 52.5% behind the medicine, and 7 days preventive effect is 73.3% and 80.3% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect pear sucker is significantly better than single dose.Embodiment 9:80% Buprofezin MTI-446 water dispersible granules (1: 50)
Buprofezin (95%) 1.7g
MTI-446 (95%) 82.6g
Negel formaldehyde condensation products (dispersant) 3g
Polycarboxylate (dispersant) 2g
Lauryl sodium sulfate (wetting agent) 3g
Polyethylene glycol (binding agent) 2g
White carbon (carrier) 5.7g
Active component, dispersant, wetting agent, binding agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder through air-flow crushing, add again a certain amount of water mixing extruding and make material.Obtain 80% Buprofezin MTI-446 water dispersible granules after the drying screening.
This embodiment is applied to prevent and treat the tea tree smaller green leaf hopper.With 5000 times of 80% Buprofezin MTI-446 water dispersible granules (Buprofezin valid density is 3 μ g/ml, MTI-446 valid density 157 μ g/ml) thin up spraying, the control efficiency of 3 days and 7 days is respectively 78.3%, 96.2% behind the medicine.25% buprofezin suspension agent by 1000 times (valid density is 250 μ g/ml) and 25% MTI-446 water dispersible granules by 1000 times (valid density is 250 μ g/ml), use with same method, use with same method, 3 days preventive effect is respectively 68.1% and 75.7% behind the medicine, and 7 days preventive effect is 80.2% and 82.4% behind the medicine.Synergistic effect is obvious behind MTI-446 and the buprofezin compound, and right preventive effect tea tree smaller green leaf hopper is significantly better than single dose.
Claims (5)
1. Pesticidal combination, it is characterized in that: the active component of said composition is comprised of Buprofezin and MTI-446, and the mass ratio of Buprofezin and MTI-446 is 50: 1~1: 50.
2. Pesticidal combination according to claim 1, it is characterized in that: the mass ratio of active ingredient Buprofezin and MTI-446 is 10: 1~1: 10.
3. Pesticidal combination according to claim 1 and 2 is characterized in that active ingredient gross mass percentage composition in composition is 1%~80%.
4. Pesticidal combination according to claim 3, the formulation that it is characterized in that composition is microemulsion, suspending agent, aqueous emulsion, water dispersible granules, missible oil and wetting powder.
5. Pesticidal combination claimed in claim 1 is used for the homoptera pest on control paddy rice, cotton, fruit tree, the vegetables.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200910164496 CN101700034B (en) | 2009-08-01 | 2009-08-01 | Pesticide composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200910164496 CN101700034B (en) | 2009-08-01 | 2009-08-01 | Pesticide composition |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101700034A CN101700034A (en) | 2010-05-05 |
CN101700034B true CN101700034B (en) | 2013-02-13 |
Family
ID=42154975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200910164496 Active CN101700034B (en) | 2009-08-01 | 2009-08-01 | Pesticide composition |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101700034B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102823618A (en) * | 2012-09-13 | 2012-12-19 | 王学权 | Insecticide containing dinotefuran |
CN104336041A (en) * | 2013-07-23 | 2015-02-11 | 张长平 | Composite pesticide and applications thereof |
CN103960277A (en) * | 2014-04-08 | 2014-08-06 | 广东中迅农科股份有限公司 | Pesticide composition containingtolfenpyrad and dinotefuran |
CN113229290A (en) * | 2021-06-17 | 2021-08-10 | 山东潍坊润丰化工股份有限公司 | Insecticidal composition containing buprofezin, chlorfenapyr and dinotefuran and application thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1411724A (en) * | 2002-10-09 | 2003-04-23 | 华南农业大学 | Nimbin and thiazinedone mixed pesticide preparation |
WO2006106798A1 (en) * | 2005-03-30 | 2006-10-12 | Nihon Nohyaku Co., Ltd. | Pest control agent and method of using the same |
CN1951193A (en) * | 2006-11-14 | 2007-04-25 | 华南理工大学 | Rotenone and dinotefuran mixed microemulsion and preparation method thereof |
CN1969626A (en) * | 2005-11-21 | 2007-05-30 | 徐学春 | Thiazine mixed pesticide |
CN101485309A (en) * | 2008-01-15 | 2009-07-22 | 连云港立本农药化工有限公司 | Environment friendly novel dosage form of nitenpyram composition |
-
2009
- 2009-08-01 CN CN 200910164496 patent/CN101700034B/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1411724A (en) * | 2002-10-09 | 2003-04-23 | 华南农业大学 | Nimbin and thiazinedone mixed pesticide preparation |
WO2006106798A1 (en) * | 2005-03-30 | 2006-10-12 | Nihon Nohyaku Co., Ltd. | Pest control agent and method of using the same |
CN1969626A (en) * | 2005-11-21 | 2007-05-30 | 徐学春 | Thiazine mixed pesticide |
CN1951193A (en) * | 2006-11-14 | 2007-04-25 | 华南理工大学 | Rotenone and dinotefuran mixed microemulsion and preparation method thereof |
CN101485309A (en) * | 2008-01-15 | 2009-07-22 | 连云港立本农药化工有限公司 | Environment friendly novel dosage form of nitenpyram composition |
Non-Patent Citations (1)
Title |
---|
王彦华等.防治褐飞虱的高毒农药替代药剂的室内筛选及交互抗性研究.《中国水稻科学》.2008,第22卷(第5期),519-526. * |
Also Published As
Publication number | Publication date |
---|---|
CN101700034A (en) | 2010-05-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101658178A (en) | Synergistic insecticidal composition | |
CN101380008A (en) | Disinsection composition with synergistic action | |
CN101755847A (en) | Metarhiziumanisopliae compound insecticide composition and use thereof | |
CN104322558A (en) | Sterilization composition and applications thereof | |
CN103271041A (en) | Complex acaricide for farmland and fruiters | |
CN105145663B (en) | A kind of plant pesticide composition containing nimbin and eucalyptus oil | |
CN101669492A (en) | Synergic agricultural pesticide composition | |
CN101700034B (en) | Pesticide composition | |
CN101669514A (en) | Synergistic pesticide composition | |
CN101406192A (en) | Compositional acaricide and uses thereof | |
CN104522054A (en) | Biological source synergistic compound insecticide, preparation method and application thereof | |
CN104604945A (en) | Insecticidal composition containing metarrhizium anisopliae and veratrine and application of insecticidal composition in rice disease prevention and control | |
CN101485329B (en) | Agricultural chemical composition for disinsection and use thereof | |
CN101843268A (en) | Botanical synergistic compound aphicide and preparation method thereof | |
CN101617676B (en) | Pesticide compound | |
CN101589720A (en) | A kind of insecticides that contains indenes worm prestige | |
CN101755813A (en) | Thiamethoxam-containing pesticidal composition and application thereof | |
CN104381294A (en) | Insect and mite killing composition containing xiaochongliulin and spirodiclofen | |
CN101444215A (en) | Desinsection composite and application thereof | |
CN106561699A (en) | Composite containing Afidopyropen and SYP-9080 | |
CN102283230B (en) | Synergistic insecticide composition taking novaluron and diafenthiuron as main active ingredients and application thereof | |
CN101622998A (en) | Pesticide composition with synergistic effect | |
CN101874498A (en) | Insect and acarid killing composition | |
CN109984142A (en) | A kind of Pesticidal combination containing double third ring worm esters and shuangweiwei | |
CN104115833A (en) | Insect and mite killing composition containing pyriproxyfen and cyflumetofen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CP03 | Change of name, title or address | ||
CP03 | Change of name, title or address |
Address after: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang Patentee after: Shenzhen Novozon Crop Science Co.,Ltd. Country or region after: China Address before: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang Patentee before: SHENZHEN NOPOSION AGROCHEMICALS Co.,Ltd. Country or region before: China |